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The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases.
Nucleic Acids Research 44
(D1): D27-D37.
4 January 2016
Von Willebrand factor gene variants associate with herpes simplex encephalitis.
Abdelmagid, N., Bereczky-Veress, B., Atanur, S., Musilová, A., Zidek, V., Saba, L., Warnecke, A., Khademi, M., Studahl, M., Aurelius, E., Hjalmarsson, A., Garcia-Diaz, A., Denis, C.V., Bergström, T., Sköldenberg, B., Kockum, I., Aitman, T., Hübner, N., Olsson, T., Pravenec, M. and Diez, M.
PLoS ONE 11
(5): e0155832.
25 May 2016
Structural determinants of sleeping beauty transposase activity.
Abrusán, G., Yant, S.R., Szilágyi, A., Marsh, J.A., Mátés, L., Izsvák, Z., Barabás, O. and Ivics, Z.
Molecular Therapy 24
(8): 1369-1377.
August 2016
Exome sequencing identifies biallelic MSH3 germline mutations as a recessive subtype of colorectal adenomatous polyposis.
Adam, R., Spier, I., Zhao, B., Kloth, M., Marquez, J., Hinrichsen, I., Kirfel, J., Tafazzoli, A., Horpaopan, S., Uhlhaas, S., Stienen, D., Friedrichs, N., Altmüller, J., Laner, A., Holzapfel, S., Peters, S., Kayser, K., Thiele, H., Holinski-Feder, E., Marra, G., Kristiansen, G., Nöthen, M.M., Büttner, R., Möslein, G., Betz, R.C., Brieger, A., Lifton, R.P. and Aretz, S.
American Journal of Human Genetics 99
(2): 337-51.
4 August 2016
The metabolic background is a global player in Saccharomyces gene expression epistasis.
Alam, M.T., Zelezniak, A., Mülleder, M., Shliaha, P., Schwarz, R., Capuano, F., Vowinckel, J., Radmaneshfar, E., Krüger, A., Calvani, E., Michel, S., Börno, S., Christen, S., Patil, K.R., Timmermann, B., Lilley, K.S. and Ralser, M.
Nature Microbiology 1
: 15030.
1 February 2016
Circulating omentin as a novel biomarker for colorectal cancer risk: Data from the EPIC - Potsdam cohort study.
Aleksandrova, K., di Giuseppe, R., Isermann, B., Biemann, R., Schulze, M.B., Wittenbecher, C., Fritsche, A., Lehmann, R., Menzel, J., Weikert, C., Pischon, T. and Boeing, H.
Cancer Research 76
(13): 3862-3871.
1 July 2016
Endogenous gibbon ape leukemia virus identified in a rodent (Melomys burtoni subsp.) from Wallacea (Indonesia).
Alfano, N., Michaux, J., Morand, S., Aplin, K., Tsangaras, K., Löber, U., Fabre, P.H., Fitriana, Y., Semiadi, G., Ishida, Y., Helgen, K.M., Roca, A.L., Eiden, M.V. and Greenwood, A.D.
Journal of Virology 90
(18): 8169-8180.
15 September 2016
Standardized benchmarking in the quest for orthologs.
Altenhoff, A.M., Boeckmann, B., Capella-Gutierrez, S., Dalquen, D.A., DeLuca, T., Forslund, K., Huerta-Cepas, J., Linard, B., Pereira, C., Pryszcz, L.P., Schreiber, F., da Silva, A.S., Szklarczyk, D., Train, C.M., Bork, P., Lecompte, O., von Mering, C., Xenarios, I., Sjölander, K., Jensen, L.J., Martin, M.J., Muffato, M., Gabaldón, T., Lewis, S.E., Thomas, P.D., Sonnhammer, E. and Dessimoz, C.
Nature Methods 13
(5): 425-430.
May 2016
A systematic comparison of two new releases of exome sequencing products: the aim of use determines the choice of product.
Altmüller, J., Motameny, S., Becker, C., Thiele, H., Chatterjee, S., Wollnik, B. and Nürnberg, P.
Biological Chemistry 397
(8): 791-801.
1 August 2016
Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome.
Ammann, S., Schulz, A., Krägeloh-Mann, I., Dieckmann, N.M.G., Niethammer, K., Fuchs, S., Eckl, K.M., Plank, R., Werner, R., Altmüller, J., Thiele, H., Nürnberg, P., Bank, J., Strauss, A., von Bernuth, H., Zur Stadt, U., Grieve, S., Griffiths, G.M., Lehmberg, K., Hennies, H.C. and Ehl, S.
Blood 127
(8): 997-1006.
25 February 2016
ISN Nexus 2016 Symposia: translational immunology in kidney disease -- the Berlin roadmap.
Anders, H.J., Rovin, B., Jayne, D., Brunetta, P., Coppo, R., Davidson, A., Devarapu, S.K., de Zeeuw, D., Duffield, J., Eulberg, D., Fierro, A., Floege, J., Frese, S., Guillevin, L., Holdsworth, S., Hughes, J., Kettritz, R., Kluger, M., Krebs, C., Lapteva, L., Levin, A., Li, J., Lightstone, L., Mack, M., Mansouri, L., McAdoo, S., McKinney, E., Panzer, U., Parikh, S., Pusey, C., Putterman, C., Rabelink, T., Radbruch, A., Rees, A., Reilly, M., Reinders, M., Remuzzi, G., Ruggenenti, P., Sacks, S., Schall, T.J., Meyer-Schwesinger, C., Sharma, K., Suzuki, Y., Tomas, N.M. and Zhao, M.H.
Kidney International Reports 1
(4): 327-339.
November 2016
Early pregnancy angiogenic markers and spontaneous abortion: an Odense Child Cohort study.
Andersen, L.B., Dechend, R., Karumanchi, S.A., Nielsen, J., Joergensen, J.S., Jensen, T.K. and Christesen, H.T.
American Journal of Obstetrics and Gynecology 215
(5): 594.e1-594.e11.
November 2016
Prediction of preeclampsia with angiogenic biomarkers. Results from the prospective Odense Child Cohort.
Andersen, L.B., Dechend, R., Jørgensen, J.S., Luef, B.M., Nielsen, J., Barington, T. and Christesen, H.T.
Hypertension in Pregnancy 35
(3): 405-419.
August 2016
Vitamin D depletion does not affect key aspects of the preeclamptic phenotype in a transgenic rodent model for preeclampsia.
Andersen, L.B., Golic, M., Przybyl, L., Sorensen, G.L., Jørgensen, J.S., Fruekilde, P., von Versen-Höynck, F., Herse, F., Højskov, C.S., Dechend, R., Christesen, H.T. and Haase, N.
Journal of the American Society of Hypertension 10
(7): 597-607.e1.
July 2016
The association between angiogenic markers and fetal sex: implications for preeclampsia research.
Andersen, L.B., Jørgensen, J.S., Herse, F., Andersen, M.S., Christesen, H.T. and Dechend, R.
Journal of Reproductive Immunology 117
: 24-29.
September 2016
Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation.
Andlauer, T.F.M., Buck, D., Antony, G., Bayas, A., Bechmann, L., Berthele, A., Chan, A., Gasperi, C., Gold, R., Graetz, C., Haas, J., Hecker, M., Infante-Duarte, C., Knop, M., Kümpfel, T., Limmroth, V., Linker, R.A., Loleit, V., Luessi, F., Meuth, S.G., Muehlau, M., Nischwitz, S., Paul, F., Pütz, M., Ruck, T., Salmen, A., Stangel, M., Stellmann, J.P., Stuerner, K.H., Tackenberg, B., Then Bergh, F., Tumani, H., Warnke, C., Weber, F., Wiendl, H., Wildemann, B., Zettl, U.K., Ziemann, U., Zipp, F., Arloth, J., Weber, P., Radivojkov-Blagojevic, M., Scheinhardt, M.O., Dankowski, T., Bettecken, T., Lichtner, P., Czamara, D., Carrillo-Roa, T., Binder, E.B., Berger, K., Bertram, L., Franke, A., Gieger, C., Herms, S., Homuth, G., Ising, M., Jöckel, K.H., Kacprowski, T., Kloiber, S., Laudes, M., Lieb, W., Lill, C.M., Lucae, S., Meitinger, T., Moebus, S., Mueller-Nurasyid, M., Nöthen, M.M., Petersmann, A., Rawal, R., Schminke, U., Strauch, K., Völzke, H., Waldenberger, M., Wellmann, J., Porcu, E., Mulas, A., Pitzalis, M., Sidore, C., Zara, I., Cucca, F., Zoledziewska, M., Ziegler, A., Hemmer, B. and Müller-Myhsok, B.
Science Advances 2
(6): e1501678.
17 June 2016
destiny: diffusion maps for large-scale single-cell data in R.
Angerer, P., Haghverdi, L., Büttner, M., Theis, F.J., Marr, C. and Buettner, F.
Bioinformatics 32
(8): 1241-1243.
15 April 2016
Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A., Roske, Y., Barth, C., Lleras Forero, L., Bravo-Rodriguez, K., Redel, Al., Kostova, S., McShane, E., Opitz, R., Faelber, K., Rau, K., Mielke, T., Daumke, O., Selbach, M., Sanchez-Garcia, E., Rocks, O., Panáková, D., Heinemann, U. and Wanker, E.E.
Nature Communications 7
: 13047.
20 October 2016
Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk.
Ashktorab, H., Hermann, P., Nouraie, M., Shokrani, B., Lee, E., Haidary, T., Brim, H. and Stein, U.
Journal of Translational Medicine 14
(1): 215.
20 July 2016
Efficacy of glatiramer acetate in neuromyelitis optica spectrum disorder: a multicenter retrospective study.
Ayzenberg, I., Schöllhammer, J., Hoepner, R., Hellwig, K., Ringelstein, M., Aktas, O., Kümpfel, T., Krumbholz, M., Trebst, C., Paul, F., Pache, F., Obermann, M., Zeltner, L., Schwab, M., Berthele, A., Jarius, S. and Kleiter, I.
Journal of Neurology 263
(3): 575-582.
March 2016
Associations of anthropometric markers with serum metabolites using a targeted metabolomics approach: results of the EPIC-potsdam study.
Bachlechner, U., Floegel, A., Steffen, A., Prehn, C., Adamski, J., Pischon, T. and Boeing, H.
Nutrition & Diabetes 6
: e215.
27 June 2016
Inhibition of DNA-topoisomerase I by acylated triterpene saponins from pittosporum angustifolium Lodd.
Baecker, C., Drwal, M.N., Preissner, R. and Lindequist, U.
Natural Products and Bioprospecting 6
(2): 141-147.
April 2016
Computational methods for prediction of in vitro effects of new chemical structures.
Banerjee, P., Siramshetty, V.B., Drwal, M.N. and Preissner, R.
Journal of Cheminformatics 8
(1): 51.
29 September 2016
Dynamics of the ligand binding domain layer during AMPA receptor activation.
Baranovic, J., Chebli, M., Salazar, H., Carbone, A.L., Faelber, K., Lau, A.Y., Daumke, O. and Plested, A.J.R.
Biophysical Journal 110
(4): 896-911.
23 February 2016
OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation.
Barrera, M., Koob, S., Dikov, D., Vogel, F. and Reichert, A.S.
FEBS Letters 590
(19): 3309-3322.
October 2016
Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration.
Barrionuevo, F.J., Hurtado, A., Kim, G.J., Real, F.M., Bakkali, M., Kopp, J.L., Sander, M., Scherer, G., Burgos, M. and Jiménez, R.
eLife 5
: e15635.
21 June 2016
Three-layered proteomic characterization of a novel ACTN4 mutation unravels its pathogenic potential in FSGS.
Bartram, M.P., Habbig, S., Pahmeyer, C., Höhne, M., Weber, L.T., Thiele, H., Altmüller, J., Kottoor, N., Wenzel, A., Krueger, M., Schermer, B., Benzing, T., Rinschen, M.M. and Beck, B.B.
Human Molecular Genetics 25
(6): 1152-1164.
15 March 2016
Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury.
Bartus, K., Galino, J., James, N.D., Hernandez-Miranda, L.R., Dawes, J.M., Fricker, F.R., Garratt, A.N., McMahon, S.B., Ramer, M.S., Birchmeier, C., Bennett, D.L.H. and Bradbury, E.J.
Brain 139
(Pt 5): 1394-1416.
May 2016
The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.
Batalha, V.L., Ferreira, D.G., Coelho, J.E., Valadas, J.S., Gomes, R., Temido-Ferreira, M., Shmidt, T., Baqi, Y., Buée, L., Müller, C.E., Hamdane, M., Outeiro, T.F., Bader, M., Meijsing, S.H., Sadri-Vakili, G., Blum, D. and Lopes, L.V.
Scientific Reports 6
: 31493.
11 August 2016
Feedback, mass conservation and reaction kinetics impact the robustness of cellular oscillations.
Baum, K., Politi, A.Z., Kofahl, B., Steuer, R. and Wolf, J.
PLoS Computational Biology 12
(12): e1005298.
27 December 2016
Maximizing information from routine staging computed tomography in functional neuroendocrine neoplasms: are there findings indicating the presence of carcinoid heart disease?
Baur, A.D.J., Kunz, F., Schwenke, C., Pschowski, R., Roepke, T.K., Pavel, M. and Denecke, T.
Journal of Computer Assisted Tomography 40
(2): 277-282.
March 2016
Gene activation by metazoan enhancers: diverse mechanisms stimulate distinct steps of transcription.
Beagrie, R.A. and Pombo, A.
BioEssays 38
(9): 881-893.
September 2016
Uwe Heinemann (17.2.1944-8.9.2016).
Beck, H., Draguhn, A., Luhmann, H. and Schmitz, D.
Neuroforum 22
(4): 137-138.
December 2016
Poly(ADP-ribosyl)ation of Methyl CpG binding domain protein 2 regulates chromatin structure.
Becker, A., Zhang, P., Allmann, L., Meilinger, D., Bertulat, B., Eck, D., Hofstaetter, M., Bartolomei, G., Hottiger, M.O., Schreiber, V., Leonhardt, H. and Cardoso, M.C.
Journal of Biological Chemistry 291
(10): 4873-4881.
4 March 2016
The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration.
Becker, M.S., Müller, P.M., Bajorat, J., Schroeder, A., Giaisi, M., Amin, E., Ahmadian, M.R., Rocks, O., Köhler, R., Krammer, P.H. and Li-Weber, M.
Oncotarget 7
(32): 51908-51921.
9 August 2016
Metabolomics enables precision medicine: "A White Paper, Community Perspective".
Beger, R.D., Dunn, W., Schmidt, M.A., Gross, S.S., Kirwan, J.A., Cascante, M., Brennan, L., Wishart, D.S., Oresic, M., Hankemeier, T., Broadhurst, D.I., Lane, A.N., Suhre, K., Kastenmüller, G., Sumner, S.J., Thiele, I., Fiehn, O. and Kaddurah-Daouk, R.
Metabolomics 12
(9): 149.
September 2016
Low 25-hydroxyvitamin D, but not the bioavailable fraction of 25-hydroxyvitamin D, is a risk factor for multiple sclerosis.
Behrens, J.R., Rasche, L., Giess, R.M., Pfuhl, C., Wakonig, K., Freitag, E., Deuschle, K., Bellmann-Strobl, J., Paul, F., Ruprecht, K. and Doerr, J.
European Journal of Neurology 23
(1): 62-67.
January 2016
Validity of visual perceptive computing for static posturography in patients with multiple sclerosis.
Behrens, J.R., Mertens, S., Krüger, T., Grobelny, A., Otte, K., Mansow-Model, S., Gusho, E., Paul, F., Brandt, A.U. and Schmitz-Hübsch, T.
Multiple Sclerosis Journal 22
(12): 1596-1606.
October 2016
Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles.
Bel Abed, H., Schoene, J., Christmann, M. and Nazare, M.
Organic & Biomolecular Chemistry 14
(36): 8520-8528.
28 September 2016
A c-Myc/miR17-92/Pten axis controls PI3K-mediated positive and negative selection in B cell development and reconstitutes CD19 deficiency.
Benhamou, D., Labi, V., Novak, R., Dai, I., Shafir-Alon, S., Weiss, A., Gaujoux, R., Arnold, R., Shen-Orr, S.S., Rajewsky, K. and Melamed, D.
Cell Reports 16
(2): 419-431.
12 July 2016
Advances in β cell replacement and regeneration strategies for treating diabetes.
Benthuysen, J.R., Carrano, A.C. and Sander, M.
Journal of Clinical Investigation 126
(10): 3651-3660.
3 October 2016
A mutation in the glutamate-rich region of RBM20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank-Starling mechanism.
Beqqali, A., Bollen, I.A.E., Rasmussen, T.B., van den Hoogenhof, M.M., van Deutekom, H.W.M., Schafer, S., Haas, J., Meder, B., Sorensen, K.E., van Oort, R.J., Mogensen, J., Hubner, N., Creemers, E.E., van der Velden, J. and Pinto, Y.M.
Cardiovascular Research 112
(1): 452-463.
1 October 2016
Isolation of eosinophils from the lamina propria of the murine small intestine.
Berek, C., Beller, A. and Chu, V.T.
Methods in Molecular Biology 1422
: 213-221.
2016
Multiple myeloma cells modify VEGF/IL-6 levels and osteogenic potential of bone marrow stromal cells via Notch/miR-223.
Berenstein, R., Nogai, A., Waechter, M., Blau, O., Kuehnel, A., Schmidt-Hieber, M., Kunitz, A., Pezzutto, A., Dörken, B. and Blau, I.W.
Molecular Carcinogenesis 55
(12): 1927-1939.
December 2016
A germline chromothripsis event stably segregating in 11 individuals through three generations.
Bertelsen, B., Nazaryan-Petersen, L., Sun, W., Mehrjouy, M.M., Xie, G., Chen, W., Hjermind, L.E., Taschner, P.E.M. and Tuemer, Z.
Genetics in Medicine 18
(5): 494-500.
May 2016
Domain-swapped T cell receptors improve the safety of TCR gene therapy.
Bethune, M.T., Gee, M.H., Bunse, M., Lee, M.S., Gschweng, E.H., Pagadala, M.S., Zhou, J., Cheng, D., Heath, J.R., Kohn, D.B., Kuhns, M.S., Uckert, W. and Baltimore, D.
eLife 5
: e19095.
8 November 2016
Replication of the association between CHRNA4 rs1044396 and harm avoidance in a large population-based sample.
Bey, K., Lennertz, L., Markett, S., Petrovsky, N., Gallinat, J., Gruender, G., Spreckelmeyer, K.N., Wienker, T.F., Mobascher, A., Dahmen, N., Thuerauf, N., Kornhuber, J., Kiefer, F., Toliat, M.R., Nuernberg, P., Winterer, G. and Wagner, M.
European Neuropsychopharmacology 26
(1): 150-155.
January 2016
Proteomics quality control : a quality control software for MaxQuant results.
Bielow, C., Mastrobuoni, G. and Kempa, S.
Journal of Proteome Research 15
(3): 777-787.
4 March 2016
Ultra-Long-term human salt balance studies reveal interrelations between sodium, potassium, and chloride intake and excretion.
Birukov, A., Rakova, N., Lerchl, K., Olde Engberink, R.H.G., Johannes, B., Wabel, P., Moissl, U., Rauh, M., Luft, F.C. and Titze, J.
American Journal of Clinical Nutrition 104
(1): 49-57.
July 2016
Angiotensin II type 1 receptor antibodies in childhood kidney transplantation.
Bjerre, A., Tangeraas, T., Heidecke, H., Dragun, D., Dechend, R. and Staff, A.C.
Pediatric Transplantation 20
(5): 627-632.
August 2016
Widespread inflammation in CLIPPERS syndrome indicated by autopsy and ultra-high-field 7T MRI.
Blaabjerg, M., Ruprecht, K., Sinnecker, T., Kondziella, D., Niendorf, T., Kerrn-Jespersen, B.M., Lindelof, M., Lassmann, H., Kristensen, B.W., Paul, F. and Illes, Z.
Neurology Neuroimmunology & Neuroinflammation 3
(3): e226.
June 2016
Systematic errors in peptide and protein identification and quantification by modified peptides.
Bogdanow, B., Zauber, H. and Selbach, M.
Molecular & Cellular Proteomics 15
(8): 2791-2801.
1 August 2016
Vasopressin lowers renal epoxyeicosatrienoic acid levels by activating soluble epoxide hydrolase.
Boldt, C., Roeschel, T., Himmerkus, N., Plain, A., Bleich, M., Labes, R., Blum, M., Krause, H., Magheli, A., Giesecke, T., Mutig, K., Rothe, M., Weldon, S.M., Dragun, D., Schunck, W.H., Bachmann, S. and Paliege, A.
American Journal of Physiology Renal Physiology 311
(6): F1198-F1210.
1 December 2016
Calcineurin and sorting-related receptor with A-type repeats interact to regulate the renal Na(+)-K(+)-2Cl(-) cotransporter.
Borschewski, A., Himmerkus, N., Boldt, C., Blankenstein, K.I., McCormick, J.A., Lazelle, R., Willnow, T.E., Jankowski, V., Plain, A., Bleich, M., Ellison, D.H., Bachmann, S. and Mutig, K.
Journal of the American Society of Nephrology 27
(1): 107-119.
January 2016
ANP system activity predicts variability of fat mass reduction and insulin sensitivity during weight loss.
Brachs, M., Wiegand, S., Leupelt, V., Ernert, A., Kintscher, U., Jumpertz von Schwarzenberg, R., Decker, A.M., Bobbert, T., Hübner, N., Chen, W., Krude, H., Spranger, J. and Mai, K.
Metabolism 65
(6): 935-943.
June 2016
Axial tubule junctions control rapid calcium signaling in atria.
Brandenburg, S., Kohl, T., Williams, G.S.B., Gusev, K., Wagner, E., Rog-Zielinska, E.A., Hebisch, E., Dura, M., Didié, M., Gotthardt, M., Nikolaev, V.O., Hasenfuss, G., Kohl, P., Ward, C.W., Lederer, W.J. and Lehnart, S.E.
Journal of Clinical Investigation 126
(10): 3999-4015.
3 October 2016
Retinal lesion evolution in susac syndrome.
Brandt, A.U., Oberwahrenbrock, T., Costello, F., Fielden, M., Gertz, K., Kleffner, I., Paul, F., Bergholz, R. and Doerr, J.
Retina 36
(2): 366-374.
February 2016
Afferent visual pathway affection in patients with PMP22 deletion-related hereditary neuropathy with liability to pressure palsies.
Brandt, A.U., Meinert-Bohn, E., Rinnenthal, J., Zimmermann, H., Mikolajczak, J., Oberwahrenbrock, T., Papazoglou, S., Pfüller, C.F., Schinzel, J., Tackenberg, B., Paul, F., Hahn, K. and Bellmann-Strobl, J.
PLoS ONE 11
(10): e0164617.
17 October 2016
Visual dysfunction, but not retinal thinning, following anti-NMDA receptor encephalitis.
Brandt, A.U., Oberwahrenbrock, T., Mikolajczak, J., Zimmermann, H., Prüss, H., Paul, F. and Finke, C.
Neurology Neuroimmunology & Neuroinflammation 3
(2): e198.
April 2016
Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination.
Braten, O., Livneh, I., Ziv, T., Admon, A., Kehat, I., Caspi, L.H., Gonen, H., Bercovich, B., Godzik, A., Jahandideh, S., Jaroszewski, L., Sommer, T., Kwon, Y.T., Guharoy, M., Tompa, P. and Ciechanover, A.
Proceedings of the National Academy of Sciences of the United States of America 113
(32): E4639-E4647.
9 August 2016
Longitudinal intravital imaging of the retina reveals long-term dynamics of immune infiltration and its effects on the glial network in experimental autoimmune uveoretinitis, without evident signs of neuronal dysfunction in the ganglion cell layer.
Bremer, D., Pache, F., Guenther, R., Hornow, J., Andresen, V., Leben, R., Mothes, R., Zimmermann, H., Brandt, A.U., Paul, F., Hauser, A.E., Radbruch, H. and Niesner, R.
Frontiers in Immunology 7
: 642.
23 December 2016
Modeling cardiovascular diseases with patient-specific human pluripotent stem cell-derived cardiomyocytes.
Burridge, P.W., Diecke, S., Matsa, E., Sharma, A., Wu, H. and Wu, J.C.
Methods in Molecular Biology 1353
: 119-130.
2016
Adaptation of external counterpulsation based on individual shear rate therapy improves endothelial function and claudication distance in peripheral artery disease.
Buschmann, E.E., Brix, M., Li, L., Doreen, J., Zietzer, A., Li, M., Buschmann, I. and Hillmeister, P.
Vasa - Zeitschrift fuer Gefaesskrankheiten 45
(4): 317-324.
18 July 2016
C-type natriuretic peptide and NPR-B signalling inhibits cardiac sympathetic neurotransmission and autonomic function.
Buttgereit, J., Shanks, J., Li, D., Hao, G., Athwal, A., Langenickel, T.H., Wright, H., da Costa Goncalves, A.C., Monti, J., Plehm, R., Popova, E., Qadri, F., Lapidus, I., Ryan, B., Özcelik, C., Paterson, D.J., Bader, M. and Herring, N.
Cardiovascular Research 112
(3): 637-644.
December 2016
Identification of parvalbumin interneurons as cellular substrate of fear memory persistence.
Caliskan, G., Mueller, I., Semtner, M., Winkelmann, A., Raza, A.S., Hollnagel, J.O., Roesler, A., Heinemann, U., Stork, O. and Meier, J.C.
Cerebral Cortex 26
(5): 2325-2340.
May 2016
Detecting actively translated open reading frames in ribosome profiling data.
Calviello, L., Mukherjee, N., Wyler, E., Zauber, H., Hirsekorn, A., Selbach, M., Landthaler, M., Obermayer, B. and Ohler, U.
Nature Methods 13
(2): 165-170.
February 2016
Sortilin regulates sorting and secretion of Sonic hedgehog.
Campbell, C., Beug, S., Nickerson, P.E.B., Peng, J., Mazerolle, C., Bassett, E., Ringuette, R., Jama, F.A., Morales, C., Christ, A. and Wallace, V.A.
Journal of Cell Science 129
(20): 3832-3844.
15 October 2016
Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections.
Cano, E., Carmona, R., Ruiz-Villalba, A., Rojas, A., Chau, Y.Y., Wagner, K.D., Wagner, N., Hastie, N.D., Munoz-Chapuli, R. and Perez-Pomares, J.M.
Proceedings of the National Academy of Sciences of the United States of America 113
(3): 656-661.
19 January 2016
Acute effects of ferumoxytol on regulation of renal hemodynamics and oxygenation.
Cantow, K., Pohlmann, A., Flemming, B., Ferrara, F., Waiczies, S., Grosenick, D., Niendorf, T. and Seeliger, E.
Scientific Reports 6
: 29965.
20 July 2016
A medical device-grade T1 and ECV phantom for global T1 mapping quality assurance - the T1 Mapping and ECV Standardization in cardiovascular magnetic resonance (T1MES) program.
Captur, G., Gatehouse, P., Keenan, K.E., Heslinga, F.G., Bruehl, R., Prothmann, M., Graves, M.J., Eames, R.J., Torlasco, C., Benedetti, G., Donovan, J., Ittermann, B., Boubertakh, R., Bathgate, A., Royet, C., Pang, W., Nezafat, Reza, Salerno, M., Kellman, P. and Moon, J.C.
Journal of Cardiovascular Magnetic Resonance 18
(1): 58.
22 September 2016
Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice.
Carmona, R., Canete, A., Cano, E., Ariza, L., Rojas, A. and Munoz-Chapuli, R.
eLife 5
: e16009.
19 September 2016
A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression.
Casado-Medrano, V., Barrio-Real, L., García-Rostán, G., Baumann, M., Rocks, O. and Caloca, M.J.
Oncotarget 7
(19): 28301-28319.
10 May 2016
4D visualization of replication foci in mammalian cells corresponding to individual replicons.
Chagin, V.O., Casas-Delucchi, C.S., Reinhart, M., Schermelleh, L., Markaki, Y., Maiser, A., Bolius, J.J., Bensimon, A., Fillies, M., Domaing, P., Rozanov, Y.M., Leonhardt, H. and Cardoso, M.C.
Nature Communications 7
: 11231.
7 April 2016
Insufficient treatment of severe depression in neuromyelitis optica spectrum disorder.
Chavarro, V.S., Mealy, M.A., Simpson, A., Lacheta, A., Pache, F., Ruprecht, K., Gold, S.M., Paul, F., Brandt, A.U. and Levy, M.
Neurology Neuroimmunology & Neuroinflammation 3
(6): e286.
December 2016
Iron and non-iron-related characteristics of multiple sclerosis and neuromyelitis optica lesions at 7T MRI.
Chawla, S., Kister, I., Wuerfel, J., Brisset, J.C., Liu, S., Sinnecker, T., Dusek, P., Haacke, E.M., Paul, F. and Ge, Y.
American Journal of Neuroradiology 37
(7): 1223-1230.
July 2016
Energy efficiency trade-offs drive nucleotide usage in transcribed regions.
Chen, W.H., Lu, G., Bork, P., Hu, S. and Lercher, M.J.
Nature Communications 7
: 11334.
21 April 2016
Integration of multi-omics data of a genome-reduced bacterium: prevalence of post-transcriptional regulation and its correlation with protein abundances.
Chen, W.H., van Noort, V., Lluch-Senar, M., Hennrich, M.L., Wodke, J.A.H., Yus, E., Alibes, A., Roma, G., Mende, D.R., Pesavento, C., Typas, A., Gavin, A.C., Serrano, L. and Bork, P.
Nucleic Acids Research 44
(3): 1192-1202.
18 February 2016
In vivo interaction proteomics in Caenorhabditis elegans embryos provides new insights into P granule dynamics.
Chen, J.X., Cipriani, P.G., Mecenas, D., Polanowska, J., Piano, F., Gunsalus, K.C. and Selbach, M.
Molecular & Cellular Proteomics 15
(5): 1642-1657.
1 May 2016
Differential dynamics of the mammalian mRNA and protein expression response to misfolding stress.
Cheng, Z., Teo, G., Krueger, S., Rock, T.M., Koh, H.W.L., Choi, H. and Vogel, C.
Molecular Systems Biology 12
(1): 855.
20 January 2016
Striatal adenosine-cannabinoid receptor interactions in rats overexpressing adenosine A2A receptors.
Chiodi, V., Ferrante, A., Ferraro, L., Potenza, R.L., Armida, M., Beggiato, S., Pezzola, A., Bader, M., Fuxe, K., Popoli, P. and Domenici, M.R.
Journal of Neurochemistry 136
(5): 907-917.
March 2016
miR-23~27~24 clusters control effector T cell differentiation and function.
Cho, S., Wu, C.J., Yasuda, T., Cruz, L.O., Khan, A.A., Lin, L.L., Nguyen, D.T., Miller, M., Lee, H.M., Kuo, M.L., Broide, D.H., Rajewsky, K., Rudensky, A.Y. and Lu, L.F.
Journal of Experimental Medicine 213
(2): 235-249.
8 February 2016
A diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms.
Choi, I.Y., Piccio, L., Childress, P., Bollman, B., Ghosh, A., Brandhorst, S., Suarez, J., Michalsen, A., Cross, A.H., Morgan, T.E., Wei, M., Paul, F., Bock, M. and Longo, V.D.
Cell Reports 15
(10): 2136-2146.
7 June 2016
Karyopherin alpha 1 regulates satellite cell proliferation and survival by modulating nuclear import.
Choo, H.J., Cutler, A., Rother, F., Bader, M. and Pavlath, G.K.
Stem Cells 34
(11): 2784-2797.
November 2016
Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.
Chu, V.T., Graf, R., Wirtz, T., Weber, T., Favret, J., Li, X., Petsch, K., Tran, N.T., Sieweke, M.H., Berek, C., Kühn, R. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113
(44): 12514-12519.
1 November 2016
Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes.
Chu, V.T., Weber, T., Graf, R., Sommermann, T., Petsch, K., Sack, U., Volchkov, P., Rajewsky, K. and Kühn, R.
BMC Biotechnology 16
(1): 4.
16 January 2016
Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study.
Chuang, S.C., Boeing, H., Vollset, S.E., Midttun, Ø., Ueland, P.M., Bueno-de-Mesquita, B., Lajous, M., Fagherazzi, G., Boutron-Ruault, M.C., Kaaks, R., Kühn, T., Pischon, T., Drogan, D., Tjønneland, A., Overvad, K., Quirós, J.R., Agudo, A., Molina-Montes, E., Dorronsoro, M., Huerta, J.M., Barricarte, A., Khaw, K.T., Wareham, N.J., Travis, R.C., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Masala, G., Agnoli, C., Tumino, R., Mattiello, A., Peeters, P.H., Weiderpass, E., Palmqvist, R., Ljuslinder, I., Gunter, M., Lu, Y., Cross, A.J., Riboli, E., Vineis, P. and Aleksandrova, K.
Immunity & Ageing 13
: 5.
25 February 2016
Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers.
Claes, G.R.F., van Tienen, F.H.J., Lindsey, P., Krapels, I.P.C., Helderman-van den Enden, A.T.J.M., Hoos, M.B., Barrois, Y.E.G., Janssen, J.W.H., Paulussen, A.D.C., Sels, J.W.E.M., Kuijpers, S.H.H., van Tintelen, J.P., van den Berg, M.P., Heesen, W.F., Garcia-Pavia, P., Perrot, A., Christiaans, I., Salemink, S., Marcelis, C.L.M., Smeets, H.J.M., Brunner, H.G., Volders, P.G.A. and van den Wijngaard, A.
European Heart Journal 37
(23): 1815-1822.
14 June 2016
Autophagy in T and B lymphocytes.
Clarke, A.J. and Simon, A.K.
Autophagy Networks in Inflammation
: 171-184.
25 August 2016
Low-grade glioma surgery in intraoperative magnetic resonance imaging: Results of a multicenter retrospective assessment of the German Study Group for Intraoperative Magnetic Resonance Imaging.
Coburger, J., Merkel, A., Scherer, M., Schwartz, F., Gessler, F., Roder, C., Pala, A., König, R., Bullinger, L., Nagel, G., Jungk, C., Bisdas, S., Nabavi, A., Ganslandt, O., Seifert, V., Tatagiba, M., Senft, C., Mehdorn, M., Unterberg, A.W., Rössler, K. and Wirtz, C.R.
Neurosurgery 78
(6): 775-86.
June 2016
miRNAs are essential for the regulation of the PI3K/AKT/FOXO pathway and receptor editing during B cell maturation.
Coffre, M., Benhamou, D., Riess, D., Blumenberg, L., Snetkova, V., Hines, M.J., Chakraborty, T., Bajwa, S., Jensen, K., Chong, M.M.W., Getu, L., Silverman, G.J., Blelloch, R., Littman, D.R., Calado, D., Melamed, D., Skok, J.A., Rajewsky, K. and Koralov, S.B.
Cell Reports 17
(9): 2271-2285.
22 November 2016
Using concept mapping in the development of the EU-PAD framework (EUropean-Physical Activity Determinants across the life course): a DEDIPAC-study.
Condello, G., Ling, F.C.M., Bianco, A., Chastin, S., Cardon, G., Ciarapica, D., Conte, D., Cortis, C., De Craemer, M., Di Blasio, A., Gjaka, M., Hansen, S., Holdsworth, M., Iacoviello, L., Izzicupo, P., Jaeschke, L., Leone, L., Manoni, L., Menescardi, C., Migliaccio, S., Nazare, J.A., Perchoux, C., Pesce, C., Pierik, F., Pischon, T., Polito, A., Puggina, A., Sannella, A., Schlicht, W., Schulz, H., Simon, C., Steinbrecher, A., MacDonncha, C. and Capranica, L.
BMC Public Health 16
(1): 1145.
9 November 2016
Serial interactome capture of the human cell nucleus.
Conrad, T., Albrecht, A.-S., Rodrigues de Melo Costa, V., Sauer, S., Meierhofer, D. and Ørom, U.A.
Nature Communications 7
: 11212.
4 April 2016
Tracking transient conformational states of T4 lysozyme at room temperature combining X-ray crystallography and site-directed spin labeling.
Consentius, P., Gohlke, U., Loll, B., Alings, C., Mueller, R., Heinemann, U., Kaupp, M., Wahl, M. and Risse, T.
Journal of the American Chemical Society 138
(39): 12868-12875.
5 October 2016
Cyanobacterial symbionts diverged in the late Cretaceous towards lineage-specific nitrogen fixation factories in single-celled phytoplankton.
Cornejo-Castillo, F.M., Cabello, A.M., Salazar, G., Sanchez-Baracaldo, P., Lima-Mendez, G., Hingamp, P., Alberti, A., Sunagawa, S., Bork, P., de Vargas, C., Raes, J., Bowler, C., Wincker, P., Zehr, J.P., Gasol, J.M., Massana, R. and Acinas, S.G.
Nature Communications 7
: 11071.
22 March 2016
Reduced uterine perfusion pressure T-helper 17 cells cause pathophysiology associated with preeclampsia during pregnancy.
Cornelius, D.C., Amaral, L.M., Wallace, K., Campbell, N., Thomas, A.J., Scott, J., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 311
(6): R1192-R1199.
1 December 2016
Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Coscia, F., Watters, K.M., Curtis, M., Eckert, M.A., Chiang, C.Y., Tyanova, S., Montag, A., Lastra, R.R., Lengyel, E. and Mann, M.
Nature Communications 7
: 12645.
26 August 2016
Asymmetric division coordinates collective cell migration in angiogenesis.
Costa, G., Harrington, K.I., Lovegrove, H.E., Page, D.J., Chakravartula, S., Bentley, K. and Herbert, S.P.
Nature Cell Biology 18
(12): 1292-1301.
December 2016
Placebo-controlled study in neuromyelitis optica : ethical and design considerations.
Cree, B.A.C., Bennett, J.L., Sheehan, M., Cohen, J., Hartung, H.P., Aktas, O., Kim, H.J., Paul, F., Pittock, S., Weinshenker, B., Wingerchuk, D., Fujihara, K., Cutter, G., Patra, K., Flor, A., Barron, G., Madani, S., Ratchford, J.N. and Katz, E.
Multiple Sclerosis Journal 22
(7): 862-872.
June 2016
Genome-wide polyadenylation maps reveal dynamic mRNA 3'-end formation in the failing human heart.
Creemers, E.E., Bawazeer, A., Ugalde, A.P., van Deutekom, H.W.M., van der Made, I., de Groot, N.E., Adriaens, M.E., Cook, S.A., Bezzina, C.R., Hubner, N., van der Velden, J., Elkon, R., Agami, R. and Pinto, Y.M.
Circulation Research 118
(3): 433-438.
5 February 2016
Glycolytic regulation of cell rearrangement in angiogenesis.
Cruys, B., Wong, B.W., Kuchnio, A., Verdegem, D., Cantelmo, A. R., Conradi, L.C., Vandekeere, S., Bouché, A., Cornelissen, I., Vinckier, S., Merks, R.M.H., Dejana, E., Gerhardt, H., Dewerchin, M., Bentley, K. and Carmeliet, P.
Nature Communications 7
: 12240.
20 July 2016
SignaFish: A zebrafish-specific signaling pathway resource.
Csalyi, K., Fazekas, D., Kadlecsik, T., Tuerei, D., Gul, L., Horvath, B., Modos, D., Demeter, A., Papai, N., Lenti, K., Csermely, P., Vellai, T., Korcsmaros, T. and Varga, M.
Zebrafish 13
(6): 541-544.
1 December 2016
Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA.
Cui, H., Schlesinger, J., Schoenhals, S., Toenjes, M., Dunkel, I., Meierhofer, D., Cano, E., Schulz, K., Berger, M.F., Haack, T., Abdelilah-Seyfried, S., Bulyk, M.L., Sauer, S. and Sperling, S.R.
Nucleic Acids Research 44
(6): 2538-2553.
7 April 2016
Comprehensive profiling of retroviral integration sites using target enrichment methods from historical koala samples without an assembled reference genome.
Cui, P., Löber, U., Alquezar-Planas, D.E., Ishida, Y., Courtiol, A., Timms, P., Johnson, R.N., Lenz, D., Helgen, K.M., Roca, A.L., Hartman, S. and Greenwood, A.D.
PeerJ 4
: e1847.
28 March 2016
Agonistic autoantibodies to the angiotensin II type 1 receptor enhance angiotensin II-induced renal vascular sensitivity and reduce renal function during pregnancy.
Cunningham, M.W., Williams, J.M., Amaral, L., Usry, N., Wallukat, G., Dechend, R. and LaMarca, B.
Hypertension 68
(5): 1308-1313.
November 2016
The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p.
Czimmerer, Z., Varga, T., Kiss, M., Vazquez, C.O., Doan-Xuan, Q.M., Rueckerl, D., Tattikota, S.G., Yan, X., Nagy, Z.S., Daniel, B., Poliska, S., Horvath, A., Nagy, G., Varallyay, E., Poy, M.N., Allen, J.E., Bacso, Z., Abreu-Goodger, C. and Nagy, L.
Genome Medicine 8
(1): 63.
31 May 2016
Quantitative assessment of muscle injury by (23)Na magnetic resonance imaging.
Dahlmann, A., Kopp, C., Linz, P., Cavallaro, A., Seuss, H., Eckardt, K.U., Luft, F.C., Titze, J., Uder, M. and Hammon, M.
SpringerPlus 5
(1): 661.
23 May 2016
GPR56 contributes to the development of acute myeloid leukemia in mice.
Daria, D., Kirsten, N., Muranyi, A., Mulaw, M., Ihme, S., Kechter, A., Hollnagel, M., Bullinger, L., Döhner, K., Döhner, H., Feuring-Buske, M. and Buske, C.
Leukemia 30
(8): 1734-1741.
August 2016
CART - a chemical annotation retrieval toolkit.
Deghou, S., Zeller, G., Iskar, M., Driessen, M., Castillo, M., van Noort, V. and Bork, P.
Bioinformatics 32
(18): 2869-2871.
15 September 2016
Self-organization of human embryonic stem cells on micropatterns.
Deglincerti, A., Etoc, F., Guerra, M.C., Martyn, I., Metzger, J., Ruzo, A., Simunovic, M., Yoney, A., Brivanlou, A.H., Siggia, E. and Warmflash, A.
Nature Protocols 11
(11): 2223-2232.
November 2016
Random focusing of tsunami waves.
Degueldre, H., Metzger, J.J., Geisel, T. and Fleischmann, R.
Nature Physics 12
(3): 259-262.
March 2016
Interleukin-7 modulates anti-tumor CD8+ T cell responses via its action on host cells.
Deiser, K., Stoycheva, D., Bank, U., Blankenstein, T. and Schüler, T.
PLoS ONE 11
(7): e0159690.
22 July 2016
The A-kinase anchoring protein (AKAP) glycogen synthase kinase 3β interaction protein (GSKIP) regulates β-catenin through its interactions with both protein kinase A (PKA) and GSK3β.
Dema, A., Schröter, M.F., Perets, E., Skroblin, P., Moutty, M.C., Deàk, V.A., Birchmeier, W. and Klussmann, E.
Journal of Biological Chemistry 291
(37): 19618-19630.
9 September 2016
Moyamoya vessel pathology imaged by ultra-high-field magnetic resonance imaging at 7.0 T.
Dengler, N.F., Madai, V.I., Wuerfel, J., von Samson-Himmelstjerna, F.C., Dusek, P., Niendorf, T., Sobesky, J. and Vajkoczy, P.
Journal of Stroke and Cerebrovascular Diseases 25
(6): 1544-1551.
June 2016
Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E., Herzog, S., Labi, V., Yasuda, T., Köchert, K., Janz, M., Villunger, A., Schmidt-Supprian, M. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113
(18): 5065-5070.
3 May 2016
Pharmacological interference with protein-protein interactions of A-kinase anchoring proteins as a strategy for the treatment of disease.
Deák, V.A. and Klussmann, E.
Current Drug Targets 17
(10): 1147-1171.
1 August 2016
The A-kinase anchoring protein GSKIP regulates GSK3β activity and controls palatal shelf fusion in mice.
Deák, V.A., Skroblin, P., Dittmayer, C., Knobeloch, K.P., Bachmann, S. and Klussmann, E.
Journal of Biological Chemistry 291
(2): 681-690.
8 January 2016
Update on the ACTG1-associated Baraitser–Winter cerebrofrontofacial syndrome.
Di Donato, N., Kuechler, A., Vergano, S., Heinritz, W., Bodurtha, J., Merchant, S.R., Breningstall, G., Ladda, R., Sell, S., Altmüller, J., Bögershausen, N., Timms, A.E., Hackmann, K., Schrock, E., Collins, S., Olds, C., Rump, A. and Dobyns, W.B.
American Journal of Medical Genetics Part A 170
(10): 2644-2651.
October 2016
Mutations in EXOSC2 are associated with a novel syndrome characterised by retinitis pigmentosa, progressive hearing loss, premature ageing, short stature, mild intellectual disability and distinctive gestalt.
Di Donato, N., Neuhann, T., Kahlert, A.K., Klink, B., Hackmann, K., Neuhann, I., Novotna, B., Schallner, J., Krause, C., Glass, I.A., Parnell, S.E., Benet-Pages, A., Nissen, A.M., Berger, W., Altmüller, J., Thiele, H., Weber, B.H.F., Schrock, E., Dobyns, W.B., Bier, A. and Rump, A.
Journal of Medical Genetics 53
(6): 419-425.
June 2016
Identification of serum metabolites associated with incident hypertension in the European Prospective Investigation into Cancer and Nutrition-Potsdam Study.
Dietrich, S., Floegel, A., Weikert, C., Pischon, T., Boeing, H. and Drogan, D.
Hypertension 68
(2): 471-477.
August 2016
Random survival forest in practice: a method for modelling complex metabolomics data in time to event analysis.
Dietrich, S., Floegel, A., Troll, M., Kühn, T., Rathmann, W., Peters, A., Sookthai, D., von Bergen, M., Kaaks, R., Adamski, J., Prehn, C., Boeing, H., Schulze, M.B., Illig, T., Pischon, T., Knueppel, S., Wang-Sattler, R. and Drogan, D.
International Journal of Epidemiology 45
(5): 1406-1420.
October 2016
Neprilysin is a mediator of alternative renin-angiotensin-system activation in the murine and human kidney.
Domenig, O., Manzel, A., Grobe, N., Königshausen, E., Kaltenecker, C.C., Kovarik, J.J., Stegbauer, J., Gurley, S.B., van Oyen, D., Antlanger, M., Bader, M., Motta-Santos, D., Santos, R.A., Elased, K.M., Säemann, M.D., Linker, R.A. and Poglitsch, M.
Scientific Reports 6
: 33678.
21 September 2016
Interaction of ARC and Daxx: a novel endogenous target to preserve motor function and cell loss after focal brain ischemia in mice.
Donath, S., An, J., Lee, S.L.L., Gertz, K., Datwyler, A.L., Harms, U., Mueller, S., Farr, T.D., Fuechtemeier, M., Lättig-Tünnemann, G., Lips, J., Foddis, M., Mosch, L., Bernard, R., Grittner, U., Balkaya, M., Kronenberg, G., Dirnagl, U., Endres, M. and Harms, C.
Journal of Neuroscience 36
(31): 8132-8148.
3 August 2016
CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells.
Drachsler, M., Kleber, S., Mateos, A., Volk, K., Mohr, N., Chen, S., Cirovic, B., Tuettenberg, J., Gieffers, C., Sykora, J., Wirtz, C.R., Mueller, W., Synowitz, M. and Martin-Villalba, A.
Cell Death & Disease 7
: e2209.
28 April 2016
Insulin-like growth factor 1 and insulin-like growth factor-binding protein 3 in relation to the risk of type 2 diabetes mellitus: Results from the EPIC-Potsdam Study.
Drogan, D., Schulze, M.B., Boeing, H. and Pischon, T.
American Journal of Epidemiology 183
(6): 553-560.
15 March 2016
Does cortisol modulate emotion recognition and empathy?
Duesenberg, M., Weber, J., Schulze, L., Schaeuffele, C., Roepke, S., Hellmann-Regen, J., Otte, C. and Wingenfeld, K.
Psychoneuroendocrinology 66
: 221-227.
April 2016
Epigenomic profiling of human CD4(+) T cells supports a linear differentiation model and highlights molecular regulators of memory development.
Durek, P., Nordström, K., Gasparoni, G., Salhab, A., Kressler, C., de Almeida, M., Bassler, K., Ulas, T., Schmidt, F., Xiong, J., Glažar, P., Klironomos, F., Sinha, A., Kinkley, S., Yang, X., Arrigoni, L., Amirabad, A.., Ardakani, F.B., Feuerbach, L., Gorka, O., Ebert, P., Müller, F., Li, N., Frischbutter, S., Schlickeiser, S., Cendon, C., Fröhler, S., Felder, B., Gasparoni, N., Imbusch, C.D., Hutter, B., Zipprich, G., Tauchmann, Y., Reinke, S., Wassilew, G., Hoffmann, U., Richter, A.S., Sieverling, L., Chang, H.D., Syrbe, U., Kalus, U., Eils, J., Brors, B., Manke, T., Ruland, J., Lengauer, T., Rajewsky, N., Chen, W., Dong, J., Sawitzki, B., Chung, H.R., Rosenstiel, P., Schulz, M.H., Schultze, J.L., Radbruch, A., Walter, J., Hamann, A. and Polansky, J.K.
Immunity 45
(5): 1148-1161.
15 November 2016
CD20-targeting immunotherapy promotes cellular senescence in B-cell lymphoma.
Däbritz, J.H.M., Yu, Y., Milanovic, M., Schönlein, M., Rosenfeldt, M.T., Dörr, J.R., Kaufmann, A.M., Dörken, B. and Schmitt, C.A.
Molecular Cancer Therapeutics 15
(5): 1074-1081.
May 2016
Ethyl cellulose nanocarriers and nanocrystals differentially deliver dexamethasone into intact, tape-stripped or sodium lauryl sulfate-exposed ex vivo human skin - assessment by intradermal microdialysis and extraction from the different skin layers.
Döge, N., Hönzke, S., Schumacher, F., Balzus, B., Colombo, M., Hadam, S., Rancan, F., Blume-Peytavi, U., Schäfer-Korting, M., Schindler, A., Rühl, E., Skov, P.S., Church, M.K., Hedtrich, S., Kleuser, B., Bodmeier, R. and Vogt, A.
Journal of Controlled Release 242
: 25-34.
28 November 2016
Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes.
Ebstein, F., Textoris-Taube, K., Keller, C., Golnik, R., Vigneron, N., Van den Eynde, B.J., Schuler-Thurner, B., Schadendorf, D., Lorenz, F.K.M., Uckert, W., Urban, S., Lehmann, A., Albrecht-Koepke, N., Janek, K., Henklein, P., Niewienda, A., Kloetzel, P.M. and Mishto, M.
Scientific Reports 6
: 24032.
6 April 2016
Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L., Czajkowski, M.T., Barth, C., Müller, P.M., McShane, E., Grunwald, S., Beaudette, P., Mecklenburg, N., Volkmer, R., Zühlke, K., Dittmar, G., Selbach, M., Hammes, A., Daumke, O., Klussmann, E., Urbé, S. and Rocks, O.
Nature Communications 7
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7 October 2016
Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak and augments drug response.
Einsele-Scholz, S., Malmsheimer, S., Bertram, K., Stehle, D., Johaenning, J., Manz, M., Daniel, P.T., Gillissen, B.F., Schulze-Osthoff, K. and Essmann, F.
Journal of Cell Science 129
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1 June 2016
Subunit-selective NMDA receptor signaling through BRAG1 and BRAG2 during synapse maturation.
Elagabani, M.N., Briševac, D., Kintscher, M., Pohle, J., Köhr, G., Schmitz, D. and Kornau, H.C.
Journal of Biological Chemistry 291
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22 April 2016
Integrin signalling regulates YAP and TAZ to control skin homeostasis.
Elbediwy, A., Vincent-Mistiaen, Z.I., Spencer-Dene, B., Stone, R.K., Boeing, S., Wculek, S.K., Cordero, J., Tan, E.H., Ridgway, R., Brunton, V.G., Sahai, E., Gerhardt, H., Behrens, A., Malanchi, I., Sansom, O.J. and Thompson, B.J.
Development 143
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15 May 2016
Evaluation of a portable armband device to assess resting energy expenditure in patients with anorexia nervosa.
Elbelt, U., Haas, V., Hofmann, T., Stengel, A., Berger, H., Jeran, S. and Klapp, B.F.
Nutrition in Clinical Practice 31
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June 2016
Ranking of dystonia severity by pairwise video comparison.
Ellermeyer, T., Otte, K., Heinrich, F., Mansow-Model, S., Kayser, B., Lipp, A., Seidel, A., Krause, P., Lauritsch, K., Gusho, E., Paul, F., Kühn, A.A., Brandt, A.U. and Schmitz-Hübsch, T.
Movement Disorders Clinical Practice 3
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November 2016
The European Hematology Association Roadmap for European Hematology Research: a consensus document.
Engert, A., Balduini, C., Brand, A., Coiffier, B., Cordonnier, C., Doehner, H., Duyvene' de Wit, T., Eichinger, S., Fibbe, W., Green, T., de Haas, F., Iolascon, A., Jaffredo, T., Rodeghiero, F., Salles, G. and Schuringa, J.J.
Haematologica 101
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February 2016
Full-length dysferlin transfer by the hyperactive Sleeping Beauty transposase restores dysferlin-deficient muscle.
Escobar, H., Schöwel, V., Spuler, S., Marg, A. and Izsvák, Z.
Molecular Therapy - Nucleic Acids 5
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19 January 2016
Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis.
Esteves de Lima, J., Bonnin, M.A., Birchmeier, C. and Duprez, D.
eLife 5
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24 August 2016
Characterization of a single genomic locus encoding the clustered protocadherin receptor diversity in Xenopus tropicalis.
Etlioglu, H.E., Sun, W., Huang, Z., Chen, W. and Schmucker, D.
G3 : Genes Genomes Genetics 6
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1 August 2016
A balance between secreted inhibitors and edge sensing controls gastruloid self-organization.
Etoc, F., Metzger, J., Ruzo, A., Kirst, C., Yoney, A., Ozair, M.Z., Brivanlou, A.H. and Siggia, E.D.
Developmental Cell 39
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7 November 2016
Non-equilibrium steady states of stochastic processes with intermittent resetting.
Eule, S. and Metzger, J.J.
New Journal of Physics 18
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March 2016
The genomic landscape of core-binding factor acute myeloid leukemias.
Faber, Z.J., Chen, X., Gedman, A.L., Boggs, K., Cheng, J., Ma, J., Radtke, I., Chao, J.R., Walsh, M.P., Song, G., Andersson, A.K., Dang, J., Dong, L., Liu, Y., Huether, R., Cai, Z., Mulder, H., Wu, G., Edmonson, M., Rusch, M., Qu, C., Li, Y., Vadodaria, B., Wang, J., Hedlund, E., Cao, X., Yergeau, D., Nakitandwe, J., Pounds, S.B., Shurtleff, S., Fulton, R.S., Fulton, L.L., Easton, J., Parganas, E., Pui, C.H., Rubnitz, J.E., Ding, L., Mardis, E.R., Wilson, R.K., Gruber, T.A., Mullighan, C.G., Schlenk, R.F., Paschka, P., Döhner, K., Döhner, H., Bullinger, L., Zhang, J., Klco, J.M. and Downing, J.R.
Nature Genetics 48
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December 2016
MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma.
Fabian, J., Opitz, D., Althoff, K., Lodrini, M., Hero, B., Volland, R., Beckers, A., de Preter, K., Decock, A., Patil, N., Abba, M., Kopp-Schneider, A., Astrahantseff, K., Wünschel, J., Pfeil, S., Ercu, M., Künkele, A., Hu, J., Thole, T., Schweizer, L., Mechtersheimer, G., Carter, D., Cheung, B.B., Popanda, O., von Deimling, A., Koster, J., Versteeg, R., Schwab, M., Marshall, G.M., Speleman, F., Erb, U., Zoeller, M., Allgayer, H., Simon, T., Fischer, M., Kulozik, A.E., Eggert, A., Witt, O., Schulte, J.H. and Deubzer, H.E.
Oncotarget 7
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11 October 2016
Concentration profiles of actin-binding molecules in lamellipodia.
Falcke, M.
Physica D: Nonlinear Phenomena 318-319
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1 April 2016
A small-molecule antagonist of the β-catenin/TCF4 interaction blocks the self-renewal of cancer stem cells and suppresses tumorigenesis.
Fang, L., Zhu, Q., Neuenschwander, M., Specker, E., Wulf-Goldenberg, A., Weis, W.I., von Kries, J.P. and Birchmeier, W.
Cancer Research 76
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15 February 2016
Immunological memory: lessons from the past and a look to the future.
Farber, D.L., Netea, M.G., Radbruch, A., Rajewsky, K. and Zinkernagel, R.M.
Nature Reviews Immunology 16
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February 2016
Single-vesicle imaging reveals different transport mechanisms between glutamatergic and GABAergic vesicles.
Farsi, Z., Preobraschenski, J., van den Bogaart, G., Riedel, D., Jahn, R. and Woehler, A.
Science 351
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26 February 2016
Generation of human induced pluripotent stem cell line from a patient with a long QT syndrome type 2.
Fatima, A., Ivanyuk, D., Herms, S., Heilmann-Heimbach, S., O'Shea, O., Chapman, C., Izsvák, Z., Farr, M., Hescheler, J. and Šarić, T.
Stem Cell Research 16
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March 2016
Vitamin D supplementation improves pathophysiology in a rat model of preeclampsia.
Faulkner, J.L., Cornelius, D.C., Amaral, L.M., Harmon, A.C., Cunningham, M.W., Darby, M.M., Ibrahim, T., Thomas, D.S., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 310
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15 February 2016
Higher-resolution MR elastography reveals early mechanical signatures of neuroinflammation in patients with clinically isolated syndrome.
Fehlner, A., Behrens, J.R., Streitberger, K.J., Papazoglou, S., Braun, J., Bellmann-Strobl, J., Ruprecht, K., Paul, F., Würfel, J. and Sack, I.
Journal of Magnetic Resonance Imaging 44
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July 2016
Reheating breakfast: Age and multitasking on a computer-based and a non-computer-based task.
Feinkohl, I., Cress, U. and Kimmerle, J.
Computers in Human Behavior 55
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February 2016
Obesity and post-operative cognitive dysfunction: a systematic review and meta-analysis.
Feinkohl, I., Winterer, G. and Pischon, T.
Diabetes/Metabolism Research and Reviews 32
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September 2016
SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin.
Ferone, G., Song, J.Y., Sutherland, K.D., Bhaskaran, R., Monkhorst, K., Lambooij, J.P., Proost, N., Gargiulo, G. and Berns, A.
Cancer Cell 30
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10 October 2016
Cardiac angiotensin-(1-12) expression and systemic hypertension in rats expressing the human angiotensinogen gene.
Ferrario, C.M., VonCannon, J.L., Jiao, Y., Ahmad, S., Bader, M., Dell'Italia, L.J., Groban, L. and Varagic, J.
American Journal of Physiology Heart and Circulatory Physiology 310
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15 April 2016
Normal volumes and microstructural integrity of deep gray matter structures in AQP4+ NMOSD.
Finke, C., Heine, J., Pache, F., Lacheta, A., Borisow, N., Kuchling, J., Bellmann-Strobl, J., Ruprecht, K., Brandt, A.U. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 3
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June 2016
Structural hippocampal damage following anti-N-methyl-D-aspartate receptor encephalitis.
Finke, C., Kopp, U.A., Pajkert, A., Behrens, J.R., Leypoldt, F., Wuerfel, J.T., Ploner, C.J., Prüss, H. and Paul, F.
Biological Psychiatry 79
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1 May 2016
Hyper-activation of ATM upon DNA-PKcs inhibition modulates p53 dynamics and cell fate in response to DNA damage.
Finzel, A., Grybowski, A., Strasen, J., Cristiano, E. and Loewer, A.
Molecular Biology of the Cell 27
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1 August 2016
Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18.
Flegel, C., Vogel, F., Hofreuter, A., Wojcik, S., Schoeder, C., Kieć-Kononowicz, K., Brockmeyer, N.H., Müller, C.E., Becker, C., Altmüller, J., Hatt, H. and Gisselmann, G.
Scientific Reports 6
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30 August 2016
DC generation from peripheral blood mononuclear cells in patients with chronic myeloid leukemia: Influence of interferons on DC yield and functional properties.
Floercken, A., Kopp, J., Kölsch, U., Meisel, C., Dörken, B., Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 12
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3 May 2016
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.
Fox, R.G., Lytle, N.K., Jaquish, D.V., Park, F.D., Ito, T., Bajaj, J., Koechlein, C.S., Zimdahl, B., Yano, M., Kopp, J., Kritzik, M., Sicklick, J., Sander, M., Grandgenett, P.M., Hollingsworth, M.A., Shibata, S., Pizzo, D., Valasek, M., Sasik, R., Scadeng, M., Okano, H., Kim, Y., MacLeod, A.R., Lowy, A.M. and Reya, T.
Nature 534
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16 June 2016
Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling.
Franco, C.A., Jones, M.L., Bernabeu, M.O., Vion, A.C., Barbacena, P., Fan, J., Mathivet, T., Fonseca, C.G., Ragab, A., Yamaguchi, T.P., Coveney, P.V., Lang, R.A. and Gerhardt, H.
eLife 5
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4 February 2016
Formation of new chromatin domains determines pathogenicity of genomic duplications.
Franke, M., Ibrahim, D.M., Andrey, G., Schwarzer, W., Heinrich, V., Schoepflin, R., Kraft, K., Kempfer, R., Jerkovic, I., Chan, W.L., Spielmann, M., Timmermann, B., Wittler, L., Kurth, I., Cambiaso, P., Zuffardi, O., Houge, G., Lambie, L., Brancati, F., Pombo, A., Vingron, M., Spitz, F. and Mundlos, S.
Nature 538
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13 October 2016
Effects of RAF inhibitors on PI3K/AKT signalling depend on mutational status of the RAS/RAF signalling axis.
Fritsche-Guenther, R., Witzel, F., Kempa, S., Brummer, T., Sers, C. and Blüthgen, N.
Oncotarget 7
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20 January 2016
RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features.
Gaidzik, V.I., Teleanu, V., Papaemmanuil, E., Weber, D., Paschka, P., Hahn, J., Wallrabenstein, T., Kolbinger, B., Köhne, C.H., Horst, H.A., Brossart, P., Held, G., Kündgen, A., Ringhoffer, M., Götze, K., Rummel, M., Gerstung, M., Campbell, P., Kraus, J.M., Kestler, H.A., Thol, F., Heuser, M., Schlegelberger, B., Ganser, A., Bullinger, L., Schlenk, R.F., Döhner, K. and Döhner, H.
Leukemia 30
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November 2016
Benign infantile seizures and paroxysmal dyskinesia caused by an SCN8A mutation.
Gardella, E., Becker, F., Møller, R.S., Schubert, J., Lemke, J.R., Larsen, L.H.G., Eiberg, H., Nothnagel, M., Thiele, H., Altmüller, J., Syrbe, S., Merkenschlager, A., Bast, T., Steinhoff, B., Nürnberg, P., Mang, Y., Bakke Møller, L., Gellert, P., Heron, S.E., Dibbens, L.M., Weckhuysen, S., Dahl, H.A., Biskup, S., Tommerup, N., Hjalgrim, H., Lerche, H., Beniczky, S. and Weber, Y.G.
Annals of Neurology 79
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March 2016
Polycomb and lung cancer: when the dosage makes the (kind of) poison.
Gargiulo, G., Citterio, E. and Serresi, M.
Molecular & Cellular Oncology 3
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May 2016
Identification and re-addressing of a transcriptionally permissive locus in the porcine genome.
Garrels, W., Mukherjee, A., Holler, S., Cleve, N., Talluri, T.R., Barg-Kues, B., Diederich, M., Köhler, P., Petersen, B., Lucas-Hahn, A., Niemann, H., Izsvák, Z., Ivics, Z. and Kues, W.A.
Transgenic Research 25
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February 2016
Sterile inflammation induced by Carbopol elicits robust adaptive immune responses in the absence of pathogen-associated molecular patterns.
Gartlan, K.H., Krashias, G., Wegmann, F., Hillson, W.R., Scherer, E.M., Greenberg, P.D., Eisenbarth, S.C., Moghaddam, A.E. and Sattentau, Q.J.
Vaccine 34
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27 April 2016
Blood flow drives lumen formation by inverse membrane blebbing during angiogenesis in vivo.
Gebala, V., Collins, R., Geudens, I., Phng, L.K. and Gerhardt, H.
Nature Cell Biology 18
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April 2016
Mapping the landscape of a eukaryotic degronome.
Geffen, Y., Appleboim, A., Gardner, R.G., Friedman, N., Sadeh, R. and Ravid, T.
Molecular Cell 63
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15 September 2016
Structural changes and lack of HCN1 channels in the binaural auditory brainstem of the naked mole-rat (Heterocephalus glaber).
Gessele, N., Garcia-Pino, E., Omerbasic, D., Park, T.J. and Koch, U.
PLoS ONE 11
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13 January 2016
Targeted application of human genetic variation can improve red blood cell production from stem cells.
Giani, F.C., Fiorini, C., Wakabayashi, A., Ludwig, L.S., Salem, R.M., Jobaliya, C.D., Regan, S.N., Ulirsch, J.C., Liang, G., Steinberg-Shemer, O., Guo, M.H., Esko, T., Tong, W., Brugnara, C., Hirschhorn, J.N., Weiss, M.J., Zon, L.I., Chou, S.T., French, D.L., Musunuru, K. and Sankaran, V.G.
Cell Stem Cell 18
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7 January 2016
TERT core promotor mutations in early-onset bladder cancer.
Giedl, J., Rogler, A., Wild, A., Riener, M.O., Filbeck, T., Burger, M., Ruemmele, P., Hurst, C., Knowles, M., Hartmann, A., Zinnall, U. and Stoehr, R.
Journal of Cancer 7
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7 May 2016
SorCS2 is required for BDNF-dependent plasticity in the hippocampus.
Glerup, S., Bolcho, U., Molgaard, S., Bøggild, S., Vaegter, C.B., Smith, A.H., Nieto-Gonzalez, J.L., Ovesen, P.L., Pedersen, L.F., Fjorback, A.N., Kjolby, M., Login, H., Holm, M.M., Andersen, O.M., Nyengaard, J.R., Willnow, T.E., Jensen, K. and Nykjaer, A.
Molecular Psychiatry 21
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December 2016
Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4(+) T cells.
Gogol-Döring, A., Ammar, I., Gupta, S., Bunse, M., Miskey, C., Chen, W., Uckert, W., Schulz, T.F., Izsvák, Z. and Ivics, Z.
Molecular Therapy 24
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March 2016
CancerResource - updated database of cancer-relevant proteins, mutations and interacting drugs.
Gohlke, B.O., Nickel, J., Otto, R., Dunkel, M. and Preissner, R.
Nucleic Acids Research 44
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4 January 2016
Recent progress in structure and dynamics of dual-membrane-spanning bacterial nanomachines.
Gold, V. and Kudryashev, M.
Current Opinion in Structural Biology 39
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August 2016
Natural killer cell reduction and uteroplacental vasculopathy.
Golic, M., Haase, N., Herse, F., Wehner, A., Vercruysse, L., Pijnenborg, R., Balogh, A., Saether, P.C., Dissen, E., Luft, F.C., Przybyl, L., Park, J.K., Alnaes-Katjavivi, P., Staff, A.C., Verlohren, S., Henrich, W., Muller, D.N. and Dechend, R.
Hypertension 68
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October 2016
A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes.
Grabundzija, I., Messing, S.A., Thomas, J., Cosby, R.L., Bilic, I., Miskey, C., Gogol-Döring, A., Kapitonov, V., Diem, T., Dalda, A., Jurka, J., Pritham, E.J., Dyda, F., Izsvák, Z. and Ivics, Z.
Nature Communications 7
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2 March 2016
Structural decoding of the netrin-1/UNC5 interaction and its therapeutical implications in cancers.
Grandin, M., Meier, M., Delcros, J.G., Nikodemus, D., Reuten, R., Patel, T.R., Goldschneider, D., Orriss, G., Krahn, N., Boussouar, A., Abes, R., Dean, Y., Neves, D., Bernet, A., Depil, S., Schneiders, F., Poole, K., Dante, R., Koch, M., Mehlen, P. and Stetefeld, J.
Cancer Cell 29
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8 February 2016
RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.
Grauel, M.K., Maglione, M., Reddy-Alla, S., Willmes, C.G., Brockmann, M.M., Trimbuch, T., Rosenmund, T., Pangalos, M., Vardar, G., Stumpf, A., Walter, A.M., Rost, B.R., Eickholt, B.J., Haucke, V., Schmitz, D., Sigrist, S.J. and Rosenmund, C.
Proceedings of the National Academy of Sciences of the United States of America 113
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11 October 2016
Comparative DNA methylation and gene expression analysis identifies novel genes for structural congenital heart diseases.
Grunert, M., Dorn, C., Cui, H., Dunkel, I., Schulz, K., Schoenhals, S., Sun, W., Berger, F., Chen, W. and Sperling, S.R.
Cardiovascular Research 112
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1 October 2016
Plankton networks driving carbon export in the oligotrophic ocean.
Guidi, L., Chaffron, S., Bittner, L., Eveillard, D., Larhlimi, A., Roux, S., Darzi, Y., Audic, S., Berline, L., Brum, J., Coelho, L.P., Espinoza, J.C.I., Malviya, S., Sunagawa, S., Dimier, C., Kandels-Lewis, S., Picheral, M., Poulain, J., Searson, S., Stemmann, L., Not, F., Hingamp, P., Speich, S., Follows, M., Karp-Boss, L., Boss, E., Ogata, H., Pesant, S., Weissenbach, J., Wincker, P., Acinas, S.G., Bork, P., de Vargas, C., Iudicone, D., Sullivan, M.B., Raes, J., Karsenti, E., Bowler, C. and Gorsky, G.
Nature 532
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28 April 2016
Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA): a 2 x 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol.
Gulati, G., Heck, S.L., Ree, A.H., Hoffmann, P., Schulz-Menger, J., Fagerland, M.W., Gravdehaug, B., von Knobelsdorff-Brenkenhoff, F., Bratland, Å., Storås, T.H., Hagve, T.A., Røsjø, H., Steine, K., Geisler, J. and Omland, T.
European Heart Journal 37
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June 2016
Splenic marginal zone granulocytes acquire an accentuated neutrophil B cell-helper phenotype in chronic lymphocytic leukemia.
Gätjen, M., Brand, F., Grau, M., Gerlach, K., Kettritz, R., Westermann, J., Anagnostopoulos, I., Lenz, P., Lenz, G., Höpken, U.E. and Rehm, A.
Cancer Research 76
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15 September 2016
Disruption of Kcc2-dependent inhibition of olfactory bulb output neurons suggests its importance in odour discrimination.
Gödde, K., Gschwend, O., Puchkov, D., Pfeffer, C.K., Carleton, A. and Jentsch, T.J.
Nature Communications 7
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8 July 2016
AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Götz, F., Roske, Y., Schulz, M.S., Autenrieth, K., Bertinetti, D., Faelber, K., Zühlke, K., Kreuchwig, A., Kennedy, E., Krause, G., Daumke, O., Herberg, F.W., Heinemann, U. and Klussmann, E.
Biochemical Journal 473
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28 June 2016
Relaxin treatment in an Ang-II-based transgenic reeclamptic-rat model.
Haase, N., Golic, M., Herse, F., Rugor, J., Linz, D., Solano, M.E., Müller, D.N. and Dechend, R.
PLoS ONE 11
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10 March 2016
Aptamer BC 007 - a broad spectrum neutralizer of pathogenic autoantibodies against G-protein-coupled receptors.
Haberland, A., Holtzhauer, M., Schlichtiger, A., Bartel, S., Schimke, I., Mueller, J., Dandel, M., Luppa, P.B. and Wallukat, G.
European Journal of Pharmacology 789
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15 October 2016
Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders.
Hadar, R., Edemann-Callesen, H., Reinel, C., Wieske, F., Voget, M., Popova, E., Sohr, R., Avchalumov, Y., Priller, J., van Riesen, C., Puls, I., Bader, M. and Winter, C.
Scientific Reports 6
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15 December 2016
Characterization, treatment patterns, and patient-related outcomes of patients with Fragile X syndrome in Germany: final results of the observational EXPLAIN-FXS study.
Haessler, F., Gaese, F., Huss, M., Kretschmar, C., Brinkman, M., Peters, H., Elstner, S., Colla, M. and Pittrow, D.
BMC Psychiatry 16
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10 September 2016
Diffusion pseudotime robustly reconstructs lineage branching.
Haghverdi, L., Büttner, M., Wolf, F.A., Buettner, F. and Theis, F.J.
Nature Methods 13
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October 2016
Role of the receptor Mas in macrophage-mediated inflammation in vivo.
Hammer, A., Yang, G., Friedrich, J., Kovacs, A., Lee, D.H., Grave, K., Jörg, S., Alenina, N., Grosch, J., Winkler, J., Gold, R., Bader, M., Manzel, A., Rump, L.C., Müller, D.N., Linker, R.A. and Stegbauer, J.
Proceedings of the National Academy of Sciences of the United States of America 113
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6 December 2016
Genomic resources for wild populations of the house mouse, Mus musculus and its close relative Mus spretus.
Harr, B., Karakoc, E., Neme, R., Teschke, M., Pfeifle, C., Pezer, Ž., Babiker, H., Linnenbrink, M., Montero, I., Scavetta, R., Abai, M.R., Molins, M.P., Schlegel, M., Ulrich, R.G., Altmüller, J., Franitza, M., Büntge, A., Künzel, S. and Tautz, D.
Scientific Data 3
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13 September 2016
A circuit basis for morphogenesis.
Harrington, K.I.S.
Theoretical Computer Science 633
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20 June 2016
The clinical outcome study for dysferlinopathy: an international multicenter study.
Harris, E., Bladen, C.L., Mayhew, A., James, M., Bettinson, K., Moore, U., Smith, F.E., Rufibach, L., Cnaan, A., Bharucha-Goebel, D.X., Blamire, A.M., Bravver, E., Carlier, P.G., Day, J.W., Díaz-Manera, J., Eagle, M., Grieben, U., Harms, M., Jones, K.J., Lochmüller, H., Mendell, J.R., Mori-Yoshimura, M., Paradas, C., Pegoraro, E., Pestronk, A., Salort-Campana, E., Schreiber-Katz, O., Semplicini, C., Spuler, S., Stojkovic, T., Straub, V., Takeda, S., Rocha, C.T., Walter, M.C. and Bushby, K.
Neurology Genetics 2
(4): e89.
4 August 2016
SORLA regulates calpain-dependent degradation of synapsin.
Hartl, D., Nebrich, G., Klein, O., Stephanowitz, H., Krause, E. and Rohe, M.
Alzheimer's & Dementia 12
(9): 952-963.
September 2016
Alternative splicing substantially diversifies the transcriptome during early photomorphogenesis and correlates with the energy availability in arabidopsis.
Hartmann, L., Drewe-Boss, P., Wiessner, T., Wagner, G., Geue, S., Lee, H.C., Obermueller, D.M., Kahles, A., Behr, J., Sinz, F.H., Raetsch, G. and Wachter, A.
Plant Cell 28
(11): 2715-2734.
November 2016
The Lupus autoantigen La prevents Mis-channeling of tRNA fragments into the human microRNA pathway.
Hasler, D., Lehmann, G., Murakawa, Y., Klironomos, F., Jakob, L., Grässer, F.A., Rajewsky, N., Landthaler, M. and Meister, G.
Molecular Cell 63
(1): 110-124.
7 July 2016
Characterizing the phenotype of multiple sclerosis-associated depression in comparison with idiopathic major depression.
Hasselmann, H., Bellmann-Strobl, J., Ricken, R., Oberwahrenbrock, T., Rose, M., Otte, C., Adli, M., Paul, F., Brandt, A.U., Finke, C. and Gold, S.M.
Multiple Sclerosis Journal 22
(11): 1476-1484.
October 2016
Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit.
Hatzold, J., Beleggia, F., Herzig, H., Altmüller, J., Nürnberg, P., Bloch, W., Wollnik, B. and Hammerschmidt, M.
eLife 5
: e14277.
15 July 2016
Branched-chain and aromatic amino acids, insulin resistance and liver specific ectopic fat storage in overweight to obese subjects.
Haufe, S., Witt, H., Engeli, S., Kaminski, J., Utz, W., Fuhrmann, J.C., Rein, D., Schulz-Menger, J., Luft, F.C., Boschmann, M. and Jordan, J.
Nutrition Metabolism and Cardiovascular Diseases 26
(7): 637-642.
July 2016
Intrinsic deregulation of vascular smooth muscle and myofibroblast differentiation in mesenchymal stromal cells from patients with systemic sclerosis.
Hegner, B., Schaub, T., Catar, R., Kusch, A., Wagner, P., Essin, K., Lange, C., Riemekasten, G. and Dragun, D.
PLoS ONE 11
(4): e0153101.
7 April 2016
Immunoadsorption of agonistic autoantibodies against α1-adrenergic receptors in patients with mild to moderate dementia.
Hempel, P., Heinig, B., Jerosch, C., Decius, I., Karczewski, P., Kassner, U., Kunze, R., Steinhagen-Thiessen, E. and Bimmler, M.
Therapeutic Apheresis and Dialysis 20
(5): 523-529.
October 2016
Complex regional pain syndrome and dysautonomia in a 14-year-old girl responsive to therapeutic plasma exchange.
Hendrickson, J.E., Hendrickson, E.T., Gehrie, E.A., Sidhu, D., Wallukat, G., Schimke, I. and Tormey, C.A.
Journal of Clinical Apheresis 31
(4): 368-374.
August 2016
Targeting MYCN-driven transcription by BET-bromodomain inhibition.
Henssen, A., Althoff, K., Odersky, A., Beckers, A., Koche, R., Speleman, F., Schäfers, S., Bell, E., Nortmeyer, M., Westermann, F., De Preter, K., Florin, A., Heukamp, L., Spruessel, A., Astrahanseff, K., Lindner, S., Sadowski, N., Schramm, A., Astorgues-Xerri, L., Riveiro, M.E., Eggert, A., Cvitkovic, E. and Schulte, J.H.
Clinical Cancer Research 22
(10): 2470-2481.
May 2016
Cytoarchitecture and probability maps of the human medial orbitofrontal cortex.
Henssen, A., Zilles, K., Palomero-Gallagher, N., Schleicher, A., Mohlberg, H., Gerboga, F., Eickhoff, S.B., Bludau, S. and Amunts, K.
Cortex 75
: 87-112.
February 2016
Forward genetic screen of human transposase genomic rearrangements.
Henssen, A.G., Jiang, E., Zhuang, J., Pinello, L., Socci, N.D., Koche, R., Gonen, M., Villasante, C.M., Armstrong, S.A., Bauer, D.E., Weng, Z. and Kentsis, A.
BMC Genomics 17
: 548.
4 August 2016
Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy.
Herling, C.D., Klaumünzer, M., Rocha, C.K., Altmüller, J., Thiele, H., Bahlo, J., Kluth, S., Crispatzu, G., Herling, M., Schiller, J., Engelke, A., Tausch, E., Döhner, H., Fischer, K., Goede, V., Nürnberg, P., Reinhardt, H.C., Stilgenbauer, S., Hallek, M. and Kreuzer, K.A.
Blood 128
(3): 395-404.
21 July 2016
DNA damage signaling instructs polyploid macrophage fate in granulomas.
Herrtwich, L., Nanda, I., Evangelou, K., Nikolova, T., Horn, V., Sagar, Erny, D., Stefanowski, J., Rogell, L., Klein, C., Gharun, K., Follo, M., Seidl, M., Kremer, B., Münke, N., Senges, J., Fliegauf, M., Aschman, T., Pfeifer, D., Sarrazin, S., Sieweke, M.H., Wagner, D., Dierks, C., Haaf, T., Ness, T., Zaiss, M.M., Voll, R.E., Deshmukh, S.D., Prinz, M., Goldmann, T., Hölscher, C., Hauser, A.E., Lopez-Contreras, A.J., Grün, D., Gorgoulis, V., Diefenbach, A., Henneke, P. and Triantafyllopoulou, A.
Cell 167
(5): 1264-1280.
17 November 2016
Identification of signature volatiles to discriminate Candida albicans, glabrata, krusei and tropicalis using gas chromatography and mass spectrometry.
Hertel, M., Hartwig, S., Schuette, E., Gillissen, B., Preissner, R., Schmidt-Westhausen, A.M., Paris, S., Kastner, I. and Preissner, S.
Mycoses 59
(2): 117-126.
February 2016
Detection of signature volatiles for cariogenic microorganisms.
Hertel, M., Preissner, R., Gillissen, B., Schmidt-Westhausen, A.M., Paris, S. and Preissner, S.
European Journal of Clinical Microbiology & Infectious Diseases 35
(2): 235-244.
February 2016
CX3CR1-dependent recruitment of mature NK cells into the central nervous system contributes to control autoimmune neuroinflammation.
Hertwig, L., Hamann, I., Romero-Suarez, S., Millward, J.M., Pietrek, R., Chanvillard, C., Stuis, H., Pollok, K., Ransohoff, R.M., Cardona, A.E. and Infante-Duarte, C.
European Journal of Immunology 46
(8): 1984-1996.
August 2016
Distinct functionality of neutrophils in multiple sclerosis and neuromyelitis optica.
Hertwig, L., Pache, F., Romero-Suarez, S., Stuerner, K.H., Borisow, N., Behrens, J., Bellmann-Strobl, J., Seeger, B., Asselborn, N., Ruprecht, K., Millward, J.M., Infante-Duarte, C. and Paul, F.
Multiple Sclerosis Journal 22
(2): 160-173.
February 2016
Physiology unmasks hypertension.
Heusser, K., Brinkmann, J., Topalidis, W., Menne, J., Haller, H., Berliner, D.., Luft, F.C., Tank, J. and Jordan, J.
Hypertension 68
(2): 252-256.
August 2016
Preserved autonomic cardiovascular regulation with cardiac pacemaker inhibition: a crossover trial using high-fidelity cardiovascular phenotyping.
Heusser, K., Tank, J., Brinkmann, J., Schroeder, C., May, M., Grosshennig, A., Wenzel, D., Diedrich, A., Sweep, F.C.G.J., Mehling, H., Luft, F.C. and Jordan, J.
Journal of the American Heart Association 5
(1): e002674.
13 January 2016
Identifying prognostic SNPs in clinical cohorts: complementing univariate ynalyses by resampling and multivariable modeling.
Hieke, S., Benner, A., Schlenk, R.F., Schumacher, M., Bullinger, L. and Binder, H.
PLoS ONE 11
(5): e0155226.
May 2016
Integrating multiple molecular sources into a clinical risk prediction signature by extracting complementary information.
Hieke, S., Benner, A., Schlenl, R.F., Schumacher, M., Bullinger, L. and Binder, H.
BMC Bioinformatics 17
(1): 327.
30 August 2016
Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy.
Hinze, F., Dieterich, C., Radke, M.H., Granzier, H. and Gotthardt, M.
Journal of Molecular Medicine 94
(12): 1349-1358.
December 2016
Early developmental stress negatively affects neuronal recruitment to avian song system nucleus HVC.
Honarmand, M., Thompson, C.K., Schatton, A., Kipper, S. and Scharff, C.
Developmental Neurobiology 76
(1): 107-118.
January 2016
Mass spectrometry based metabolomics comparison of liver grafts from donors after circulatory death (DCD) and donors after brain death (DBD) used in human orthotopic liver transplantation.
Hrydziuszko, O., Perera, M.T.P.R., Laing, R., Kirwan, J., Silva, M.A., Richards, D.A., Murphy, N., Mirza, D.F. and Viant, M.R.
PLoS ONE 11
(11): e0165884.
11 November 2016
Super-resolution ribosome profiling reveals unannotated translation events in Arabidopsis.
Hsu, P.Y., Calviello, L., Wu, H.Y.L., Li, F.W., Rothfels, C.J., Ohler, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 113
(45): E7126-E7135.
8 November 2016
X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes.
Hu, H., Haas, S.A., Chelly, J., Van Esch, H., Raynaud, M., de Brouwer, A.P.M., Weinert, S., Froyen, G., Frints, S.G.M., Laumonnier, F., Zemojtel, T., Love, M.I., Richard, H., Emde, A.K., Bienek, M., Jensen, C., Hambrock, M., Fischer, U., Langnick, C., Feldkamp, M., Wissink-Lindhout, W., Lebrun, N., Castelnau, L., Rucci, J., Montjean, R., Dorseuil, O., Billuart, P., Stuhlmann, T., Shaw, M., Corbett, M.A., Gardner, A., Willis-Owen, S., Tan, C., Friend, K.L., Belet, S., van Roozendaal, K.E.P., Jimenez-Pocquet, M., Moizard, M.P., Ronce, N., Sun, R., O'Keeffe, S., Chenna, R., van Bömmel, A., Goeke, J., Hackett, A., Field, M., Christie, L., Boyle, J., Haan, E., Nelson, J., Turner, G., Baynam, G., Gillessen-Kaesbach, G., Mueller, U., Steinberger, D., Budny, B., Badura-Stronka, M., Latos-Bieleńska, A., Ousager, L.B., Wieacker, P., Rodríguez Criado, G., Bondeson, M.L., Annerén, G., Dufke, A., Cohen, M., Van Maldergem, L., Vincent-Delorme, C., Echenne, B., Simon-Bouy, B., Kleefstra, T., Willemsen, M., Fryns, J.P., Devriendt, K., Ullmann, R., Vingron, M., Wrogemann, K., Wienker, T.F., Tzschach, A., van Bokhoven, H., Gecz, J., Jentsch, T.J., Chen, W., Ropers, H.H. and Kalscheuer, V.M.
Molecular Psychiatry 21
(1): 133-148.
January 2016
Delivery of therapeutics targeting the mRNA-binding protein HuR using 3DNA nanocarriers suppresses ovarian tumor growth.
Huang, Y.H., Peng, W., Furuuchi, N., Gerhart, J., Rhodes, K., Mukherjee, N., Jimbo, M., Gonye, G.E., Brody, J.R., Getts, R.C. and Sawicki, J.A.
Cancer Research 76
(6): 1549-1559.
15 March 2016
SNX27 and SORLA interact to reduce amyloidogenic subcellular distribution and processing of amyloid precursor protein.
Huang, T.Y., Zhao, Y., Li, X., Wang, X., Tseng, I.C., Thompson, R., Tu, S., Willnow, T.E., Zhang, Y.W. and Xu, H.
Journal of Neuroscience 36
(30): 7996-8011.
27 July 2016
Protein abundance control by non-coding antisense transcription.
Huber, F., Bunina, D., Gupta, I., Khmelinskii, A., Meurer, M., Theer, P., Steinmetz, L.M. and Knop, M.
Cell Reports 15
(12): 2625-2636.
21 June 2016
ETE 3: reconstruction, analysis and visualization of phylogenomic data.
Huerta-Cepas, J., Serra, F. and Bork, P.
Molecular Biology and Evolution 33
(6): 1635-1638.
June 2016
eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences.
Huerta-Cepas, J., Szklarczyk, D., Forslund, K., Cook, H., Heller, D., Walter, M.C., Rattei, T., Mende, D.R., Sunagawa, S., Kuhn, M., Jensen, L.J., von Mering, C. and Bork, P.
Nucleic Acids Research 44
(D1): D286-D293.
4 January 2016
Retinal imaging and axonal degeneration in later onset multiple sclerosis.
Huhn, K., Laemmer, R., Zimmermann, H., Lämmer, A., Waschbisch, A., Utz, K., Gieß, R.M., Paul, F., Linker, R.A. and Lee, D.H.
Journal of the Neurological Sciences 370
: 1-6.
15 November 2016
Importance of cerebrospinal fluid analysis in the era of McDonald 2010 criteria: a German-Austrian retrospective multicenter study in patients with a clinically isolated syndrome.
Huss, A.M., Halbgebauer, S., Öckl, P., Trebst, C., Spreer, A., Borisow, N., Harrer, A., Brecht, I., Balint, B., Stich, O., Schlegel, S., Retzlaff, N., Winkelmann, A., Roesler, R., Lauda, F., Yildiz, O., Voss, E., Muche, R., Rauer, S., Bergh, F.T., Otto, M., Paul, F., Wildemann, B., Kraus, J., Ruprecht, K., Stangel, M., Buttmann, M., Zettl, U.K. and Tumani, H.
Journal of Neurology 263
(12): 2499-2504.
December 2016
Activation of peroxisome proliferator-activated receptor-δ as novel therapeutic strategy to prevent in-stent restenosis and stent thrombosis.
Hytönen, J., Leppänen, O., Braesen, J.H., Schunck, W.H., Mueller, D., Jung, F., Mrowietz, C., Jastroch, M., von Bergwelt-Baildon, M., Kappert, K., Heuser, A., Drenckhahn, J.D., Pieske, B., Thierfelder, L., Ylä-Herttuala, S. and Blaschke, F.
Arteriosclerosis Thrombosis and Vascular Biology 36
(8): 1534-1548.
August 2016
Influence of Th2 cytokines on the cornified envelope, tight junction proteins, and ß-defensins in filaggrin-deficient skin equivalents.
Hönzke, S., Wallmeyer, L., Ostrowski, A., Radbruch, M., Mundhenk, L., Schäfer-Korting, M. and Hedtrich, S.
Journal of Investigative Dermatology 136
(3): 631-639.
March 2016
Hermes regulates axon sorting in the optic tract by post-trancriptional regulation of Neuropilin 1.
Hörnberg, H., Cioni, J.M., Harris, W.A. and Holt, C.E.
Journal of Neuroscience 36
(50): 12697-12706.
14 December 2016
Using light sheet fluorescence microscopy to image zebrafish eye development.
Icha, J., Schmied, C., Sidhaye, J., Tomancak, P., Preibisch, S. and Norden, C.
Journal of Visualized Experiments 2016
(110): e53966.
10 April 2016
TLR2 controls random motility, while TLR7 regulates chemotaxis of microglial cells via distinct pathways.
Ifuku, M., Buonfiglioli, A., Jordan, P., Lehnardt, S. and Kettenmann, H.
Brain Behavior and Immunity 58
: 338-347.
November 2016
MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer.
Ilm, K., Fuchs, S., Mudduluru, G. and Stein, U.
Oncotarget 7
(33): 53443-53458.
16 August 2016
SL2: an interactive webtool for modeling of missing segments in proteins.
Ismer, J., Rose, A.S., Tiemann, J.K.S., Goede, A., Preissner, R. and Hildebrand, P.W.
Nucleic Acids Research 44
(W1): W390-W394.
8 July 2016
Pluripotency and the endogenous retrovirus HERVH: Conflict or serendipity?
Izsvák, Z., Wang, J., Singh, M., Mager, D.L. and Hurst, L.D.
BioEssays 38
(1): 109-117.
January 2016
Automated annotation and evaluation of in-source mass spectra in GC/atmospheric pressure chemical ionization-MS-based metabolomics.
Jaeger, C., Hoffmann, F., Schmitt, C.A. and Lisec, J.
Analytical Chemistry 88
(19): 9386-9390.
4 October 2016
Data integration for identification of important transcription factors of STAT6-mediated cell fate decisions.
Jargosch, M., Kroeger, S., Gralinska, E., Klotz, U., Fang, Z., Chen, W., Leser, U., Selbig, J., Groth, D. and Baumgrass, R.
Genetics and Molecular Research 15
(2): gmr.15028493.
24 June 2016
MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome.
Jarius, S., Kleiter, I., Ruprecht, K., Asgari, N., Pitarokoili, K., Borisow, N., Hümmert, M.W., Trebst, C., Pache, F., Winkelmann, A., Beume, L.A., Ringelstein, M., Stich, O., Aktas, O., Korporal-Kuhnke, M., Schwarz, A., Lukas, C., Haas, J., Fechner, K., Buttmann, M., Bellmann-Strobl, J., Zimmermann, H., Brandt, A.U., Franciotta, D., Schanda, K., Paul, F., Reindl, M. and Wildemann, B.
Journal of Neuroinflammation 13
(1): 281.
1 November 2016
Screening for MOG-IgG and 27 other anti-glial and anti-neuronal autoantibodies in 'pattern II multiple sclerosis' and brain biopsy findings in a MOG-IgG-positive case.
Jarius, S., Metz, I., König, F.B., Ruprecht, K., Reindl, M., Paul, F., Brück, W. and Wildemann, B.
Multiple Sclerosis Journal 22
(12): 1541-1549.
October 2016
MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome.
Jarius, S., Ruprecht, K., Kleiter, I., Borisow, N., Asgari, N., Pitarokoili, K., Pache, F., Stich, O., Beume, L.A., Hümmert, M.W., Ringelstein, M., Trebst, C., Winkelmann, A., Schwarz, A., Buttmann, M., Zimmermann, H., Kuchling, J., Franciotta, D., Capobianco, M., Siebert, E., Lukas, C., Korporal-Kuhnke, M., Haas, J., Fechner, K., Brandt, A.U., Schanda, K., Aktas, O., Paul, F., Reindl, M. and Wildemann, B.
Journal of Neuroinflammation 13
(1): 280.
28 October 2016
MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin.
Jarius, S., Ruprecht, K., Kleiter, I., Borisow, N., Asgari, N., Pitarokoili, K., Pache, F., Stich, O., Beume, L.A., Hümmert, M.W., Trebst, C., Ringelstein, M., Aktas, O., Winkelmann, A., Buttmann, M., Schwarz, A., Zimmermann, H., Brandt, A.U., Franciotta, D., Capobianco, M., Kuchling, J., Haas, J., Korporal-Kuhnke, M., Lillevang, S.T., Fechner, K., Schanda, K., Paul, F., Wildemann, B. and Reindl, M.
Journal of Neuroinflammation 13
(1): 279.
26 September 2016
A pipeline for PAR-CLIP data analysis.
Jens, M.
Methods in Molecular Biology 1358
: 197-207.
2016
Amyloid-β(1-42) aggregation initiates its cellular uptake and cytotoxicity.
Jin, S., Kedia, N., Illes-Toth, E., Haralampiev, I., Prisner, S., Herrmann, A., Wanker, E.E. and Bieschke, J.
Journal of Biological Chemistry 291
(37): 19590-19606.
9 September 2016
Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.
Jung, B., Messias, A.C., Schorpp, K., Geerlof, A., Schneider, G., Saur, D., Hadian, K., Sattler, M., Wanker, E.E., Hasenöder, S. and Lickert, H.
Scientific Reports 6
: 22540.
2 March 2016
Status of diagnostic approaches to AQP4-IgG seronegative NMO and NMO/MS overlap syndromes.
Juryńczyk, M., Weinshenker, B., Akman-Demir, G., Asgari, N., Barnes, D., Boggild, M., Chaudhuri, A., D'hooghe, M., Evangelou, N., Geraldes, R., Illes, Z., Jacob, A., Kim, H.J., Kleiter, I., Levy, M., Marignier, R., McGuigan, C., Murray, K., Nakashima, I., Pandit, L., Paul, F., Pittock, S., Selmaj, K., de Sèze, J., Siva, A., Tanasescu, R., Vukusic, S., Wingerchuk, D., Wren, D., Leite, I. and Palace, J.
Journal of Neurology 263
(1): 140-149.
January 2016
Assessment of costimulation and coinhibition in a triple parameter T cell reporter line: Simultaneous measurement of NF-κB, NFAT and AP-1.
Jutz, S., Leitner, J., Schmetterer, K., Doel-Perez, I., Majdic, O., Grabmeier-Pfistershammer, K., Paster, W., Huppa, J.B. and Steinberger, P.
Journal of Immunological Methods 430
: 10-20.
March 2016
High salt drives Th17 responses in experimental autoimmune encephalomyelitis without impacting myeloid dendritic cells.
Jörg, S., Kissel, J., Manzel, A., Kleinewietfeld, M., Haghikia, A., Gold, R., Müller, D.N. and Linker, R.A.
Experimental Neurology 279
: 212-222.
May 2016
The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.
Kabat, A.M., Harrison, O.J., Riffelmacher, T., Moghaddam, A.E., Pearson, C.F., Laing, A., Abeler-Dörner, L., Forman, S.P., Grencis, R.K., Sattentau, Q., Simon, A.K., Pott, J. and Maloy, K.J.
eLife 5
: e12444.
11 March 2016
Longitudinal study to assess the clinical significance of MSI2 expression in chronic myeloid keukemia patients.
Kaeda, J., Ringel, F., Oberender, C., Gresse, M., Amini, L., Schwarz, M., Doerken, B. and le Coutre, P.
Acta Haematologica 136
(1): 62-64.
June 2016
Pericardial tamponade in an adult suffering from acute mumps infection.
Kahlfuss, S., Flieger, R.R., Mankertz, A., Yilmaz, K. and Roepke, T.K.
Case Reports in Medicine 2016
: 7980936.
12 October 2016
Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.
Kaminski, M.M., Tosic, J., Kresbach, C., Engel, H., Klockenbusch, J., Müller, A.L., Pichler, R., Grahammer, F., Kretz, O., Huber, T.B., Walz, G., Arnold, S.J. and Lienkamp, S.S.
Nature Cell Biology 18
(12): 1269-1280.
December 2016
M-CSF improves protection against bacterial and fungal infections after hematopoietic stem/progenitor cell transplantation.
Kandalla, P.K., Sarrazin, S., Molawi, K., Berruyer, C., Redelberger, D., Favel, A., Bordi, C., de Bentzmann, S. and Sieweke, M.H.
Journal of Experimental Medicine 213
(11): 2269-2279.
10 October 2016
Bacteriophage tailspikes and bacterial O-antigens as a model system to study weak-affinity protein-polysaccharide interactions.
Kang, Y., Gohlke, U., Engström, O., Hamark, C., Scheidt, T., Kunstmann, S., Heinemann, U., Widmalm, G., Santer, M. and Barbirz, S.
Journal of the American Chemical Society 138
(29): 9109-9118.
27 July 2016
Systems genetics analysis of a recombinant inbred mouse cell culture panel reveals Wnt pathway member Lrp6 as a regulator of adult hippocampal precursor cell proliferation.
Kannan, S., Nicola, Z., Overall, R.W., Ichwan, M., Ramírez-Rodríguez, G., Grzyb, A., Patone, G., Saar, K., Hübner, N. and Kempermann, G.
Stem Cells 34
(3): 674-684.
March 2016
G-quadruplex prediction in E. coli genome reveals a conserved putative G-quadruplex-hairpin-duplex switch.
Kaplan, O.I., Berber, B., Hekim, N. and Doluca, O.
Nucleic Acids Research 44
(19): 9083-9095.
2 November 2016
Autoionization in time-dependent density-functional theory.
Kapoor, V.
Physical Review A 93
(6): 063408.
8 June 2016
Regional regulation of filiform tongue papillae development by Ikkα/Irf6.
Kawasaki, M., Kawasaki, K., Oommen, S., Blackburn, J., Watanabe, M., Nagai, T., Kitamura, A., Maeda, T., Liu, B., Schmidt-Ullrich, R., Akiyama, T., Inoue, J.I., Hammond, N.L., Sharpe, P.T. and Ohazama, A.
Developmental Dynamics 245
(9): 937-946.
September 2016
SPIRE, a modular pipeline for eQTL analysis of RNA-Seq data, reveals a regulatory hotspot controlling miRNA expression in C. elegans.
Kel, I., Chang, Z., Galluccio, N., Romeo, M., Beretta, S., Diomede, L., Mezzelani, A., Milanesi, L., Dieterich, C. and Merelli, I.
Molecular BioSystems 12
(11): 3447-3458.
1 November 2016
Power estimation for non-standardized multisite studies.
Keshavan, A., Paul, F., Beyer, M.K., Zhu, A.H., Papinutto, N., Shinohara, R.T., Stern, W., Amann, M., Bakshi, R., Bischof, A., Carriero, A., Comabella, M., Crane, J.C., D'Alfonso, S., Demaerel, P., Dubois, B., Filippi, M., Fleischer, V., Fontaine, B., Gaetano, L., Goris, A., Graetz, C., Gröger, A., Groppa, S., Hafler, D.A., Harbo, H.F., Hemmer, B., Jordan, K., Kappos, L., Kirkish, G., Llufriu, S., Magon, S., Martinelli-Boneschi, F., McCauley, J., Montalban, X., Muhlau, M., Pelletier, D., Pattany, P.M., Pericak-Vance, M., Rebeix, I., Rocca, M., Rovira, A., Schlaeger, R., Saiz, A., Sprenger, T., Stecco, A., Uitdehaag, B.M.J., Villoslada, P., Wattjes, M.P., Weiner, H., Wuerfel, J., Zimmer, C., Zipp, F., Hauser, S., Oksenberg, J.R. and Henry, R.G.
NeuroImage 134
: 281-294.
1 July 2016
Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity.
Kieback, E., Hilgenberg, E., Stervbo, U., Lampropoulou, V., Shen, P., Bunse, M., Jaimes, Y., Boudinot, P., Radbruch, A., Klemm, U., Kühl, A.A., Liblau, R., Hoevelmeyer, N., Anderton, S.M., Uckert, W. and Fillatreau, S.
Immunity 44
(5): 1114-1126.
17 May 2016
reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in CD4(+) memory T cells.
Kinkley, S., Helmuth, J., Polansky, J.K., Dunkel, I., Gasparoni, G., Froehler, S., Chen, W., Walter, J., Hamann, A. and Chung, H.R.
Nature Communications 7
: 12514.
17 August 2016
Benefits and risks of aliskiren treatment in patients with type 2 diabetes: analyses of the 3A registry.
Kistner, I., Zeymer, U., Dechend, R., Hagedorn, I., Riemer, T., Bramlage, P., Pittrow, D., Senges, J. and Schmieder, R.E.
Journal of Clinical Hypertension 18
(10): 1045-1053.
October 2016
Chemical proteomics reveals ferrochelatase as a common off-target of kinase inhibitors.
Klaeger, S., Gohlke, B., Perrin, J., Gupta, V., Heinzlmeir, S., Helm, D., Qiao, H., Bergamini, G., Handa, H., Savitski, M.M., Bantscheff, M., Medard, G., Preissner, R. and Kuster, B.
ACS Chemical Biology 11
(5): 1245-1254.
20 May 2016
Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells.
Klawitter, S., Fuchs, N.V., Upton, K.R., Muñoz-Lopez, M., Shukla, R., Wang, J., Garcia-Cañadas, M., Lopez-Ruiz, C., Gerhardt, D.J., Sebe, A., Grabundzija, I., Merkert, S., Gerdes, P., Pulgarin, J.A., Bock, A., Held, U., Witthuhn, A., Haase, A., Sarkadi, B., Löwer, J., Wolvetang, E.J., Martin, U., Ivics, Z., Izsvák, Z., Garcia-Perez, J.L., Faulkner, G.J. and Schumann, G.G.
Nature Communications 7
: 10286.
8 January 2016
Diagnostic criteria for Susac syndrome.
Kleffner, I., Dörr, J., Ringelstein, M., Gross, C.C., Böckenfeld, Y., Schwindt, W., Sundermann, B., Lohmann, H., Wersching, H., Promesberger, J., von Königsmarck, N., Alex, A., Guthoff, R., Frijns, C.J.M., Kappelle, L.J., Jarius, S., Wildemann, B., Aktas, O., Paul, F., Wiendl, H. and Duning, T.
Journal of Neurology Neurosurgery and Psychiatry 87
(12): 1287-1295.
25 December 2016
Optimization of the All-D peptide D3 for Aβ oligomer elimination.
Klein, A.N., Ziehm, T., Tusche, M., Buitenhuis, J., Bartnik, D., Boeddrich, A., Wiglenda, T., Wanker, E., Funke, S.A., Brener, O., Gremer, L., Kutzsche, J. and Willbold, D.
PLoS ONE 11
(4): e0153035.
22 April 2016
Early cortical changes in gamma oscillations in Alzheimer's disease.
Klein, A.S., Donoso, J.R., Kempter, R., Schmitz, D. and Beed, P.
Frontiers in Systems Neuroscience 10
: 83.
26 October 2016
Neuromyelitis optica: evaluation of 871 attacks and 1153 treatment courses.
Kleiter, I., Gahlen, A., Borisow, N., Fischer, K., Wernecke, K.D., Wegner, B., Hellwig, K., Pache, F., Ruprecht, K., Havla, J., Krumbholz, M., Kümpfel, T., Aktas, O., Hartung, H.P., Ringelstein, M., Geis, C., Kleinschnitz, C., Berthele, A., Hemmer, B., Angstwurm, K., Stellmann, J.P., Schuster, S., Stangel, M., Lauda, F., Tumani, H., Mayer, C., Zeltner, L., Ziemann, U., Linker, R., Schwab, M., Marziniak, M., Bergh, F.T., Hofstadt-van Oy, U., Neuhaus, O., Winkelmann, A., Marouf, W., Faiss, J., Wildemann, B., Paul, F., Jarius, S. and Trebst, C.
Annals of Neurology 79
(2): 206-216.
February 2016
Monitoring von Blutparametern unter verlaufsmodifizierender MS-Therapie : Substanzspezifische Relevanz und aktuelle Handlungsempfehlungen [Monitoring of blood parameters under course-modified MS therapy : substance-specific relevance and current recommendations for action].
Klotz, L., Berthele, A., Brück, W., Chan, A., Flachenecker, P., Gold, R., Haghikia, A., Hellwig, K., Hemmer, B., Hohlfeld, R., Korn, T., Kümpfel, T., Lang, M., Limmroth, V., Linker, R.A., Meier, U., Meuth, S.G., Paul, F., Salmen, A., Stangel, M., Tackenberg, B., Tumani, H., Warnke, C., Weber, M.S., Ziemssen, T., Zipp, F. and Wiendl, H.
Nervenarzt 87
(6): 645-659.
June 2016
B cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B cell lymphoma in mice.
Knittel, G., Liedgens, P., Korovkina, D., Seeger, J.M., Al-Baldawi, Y., Al-Maarri, M., Fritz, C., Vlantis, K., Bezhanova, S., Scheel, A.H., Wolz, O.O., Reimann, M., Möller, P., López, C., Schlesner, M., Lohneis, P., Weber, A.N.R., Trümper, L., Staudt, L.M., Ortmann, M., Pasparakis, M., Siebert, R., Schmitt, C.A., Klatt, A.R., Wunderlich, F.T., Schäfer, S.C., Persigehl, T., Montesinos-Rongen, M., Odenthal, M., Büttner, R., Frenzel, L.P., Kashkar, H. and Reinhardt, H.C.
Blood 127
(22): 2732-2741.
2 June 2016
Critical illness polyneuropathy in ICU patients is related to reduced motor nerve excitability caused by reduced sodium permeability.
Koch, S., Bierbrauer, J., Haas, K., Wolter, S., Grosskreutz, J., Luft, F.C., Spies, C.D., Fielitz, J. and Weber-Carstens, S.
Intensive Care Medicine Experimental 4
(1): 10.
20 May 2016
The histone methyltransferase Setd7 promotes pancreatic progenitor identity.
Kofent, J., Zhang, J. and Spagnoli, F.M.
Development 143
(19): 3573-3581.
1 October 2016
Genetic association analysis based on a joint model of gene expression and blood pressure.
Konigorski, S., Yilmaz, Y.E. and Pischon, T.
BMC Proceedings 10
(Suppl 7): 289-294.
18 October 2016
Deletion of polycomb repressive complex 2 from mouse intestine causes loss of stem cells.
Koppens, M.A.J., Bounova, G., Gargiulo, G., Tanger, E., Janssen, H., Cornelissen-Steijger, P., Blom, M., Song, J.Y., Wessels, L.F.A. and van Lohuizen, M.
Gastroenterology 151
(4): 684-697.
October 2016
Phase II trial of temsirolimus for relapsed/refractory primary CNS lymphoma.
Korfel, A., Schlegel, U., Herrlinger, U., Dreyling, M., Schmidt, C., von Baumgarten, L., Pezzutto, A., Grobosch, T., Kebir, S., Thiel, E., Martus, P. and Kiewe, P.
Journal of Clinical Oncology 34
(15): 1757-1763.
20 May 2016
Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children.
Korpela, K., Salonen, A., Virta, L.J., Kekkonen, R.A., Forslund, K., Bork, P. and de Vos, W.M.
Nature Communications 7
: 10410.
26 January 2016
Spontaneous Ca(2+) transients in mouse microglia.
Korvers, L., de Andrade Costa, A., Mersch, M., Matyash, V., Kettenmann, H. and Semtner, M.
Cell Calcium 60
(6): 396-406.
December 2016
Functional interaction of CCAAT/enhancer-binding-protein-α basic region mutants with E2F transcription factors and DNA.
Kowenz-Leutz, E., Schuetz, A., Liu, Q., Knoblich, M., Heinemann, U. and Leutz, A.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1859
(7): 841-847.
July 2016
MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR.
Krause, C.J., Popp, O., Thirunarayanan, N., Dittmar, G., Lipp, M. and Mueller, G.
Oncotarget 7
(9): 10414-10432.
1 March 2016
Predictive and prognostic value of sPRR in patients with primary epithelial ovarian cancer.
Kreienbring, K., Franz, A., Richter, R., Dragun, D., Heidecke, H., Dechend, R., Mueller, D.N., Sehouli, J. and Braicu, E.I.
Analytical Cellular Pathology 2016
: 6845213.
2016
Bi-allelic truncating mutations in TANGO2 cause infancy-onset recurrent metabolic crises with encephalocardiomyopathy.
Kremer, L.S., Distelmaier, F., Alhaddad, B., Hempel, M., Iuso, A., Küpper, C., Mühlhausen, C., Kovacs-Nagy, R., Satanovskij, R., Graf, E., Berutti, R., Eckstein, G., Durbin, R., Sauer, S., Hoffmann, G.F., Strom, T.M., Santer, R., Meitinger, T., Klopstock, T., Prokisch, H. and Haack, T.B.
American Journal of Human Genetics 98
(2): 358-362.
4 February 2016
Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis.
Kreye, J., Wenke, N.K., Chayka, M., Leubner, J., Murugan, R., Maier, N., Jurek, B., Ly, L.T., Brandl, D., Rost, B.R., Stumpf, A., Schulz, P., Radbruch, H., Hauser, A.E., Pache, F., Meisel, A., Harms, L., Paul, F., Dirnagl, U., Garner, C., Schmitz, D., Wardemann, H. and Prüss, H.
Brain 139
(10): 2641-2652.
1 October 2016
Increased brain-derived neurotrophic factor (BDNF) protein concentrations in mice lacking brain serotonin.
Kronenberg, G., Mosienko, V., Gertz, K., Alenina, N., Hellweg, R. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 266
(3): 281-284.
April 2016
A large deletion in RPGR causes XLPRA in Weimaraner dogs.
Kropatsch, R., Akkad, D.A., Frank, M., Rosenhagen, C., Altmüller, J., Nürnberg, P., Epplen, J.T. and Dekomien, G.
Canine Genetics and Epidemiology 3
: 7.
8 July 2016
Neutropenic sepsis in the ICU: Outcome predictors in a two-phase model and microbiology findings.
Kruse, J.M., Jenning, T., Rademacher, S., Arnold, R., Schmitt, C.A., Jörres, A., Enghard, P. and Oppert, M.
Critical Care Research and Practice 2016
: 8137850.
2016
ERK1 as a therapeutic target for dendritic cell vaccination against high-grade gliomas.
Ku, M.C., Edes, I., Bendix, I., Pohlmann, A., Waiczies, H., Prozorovski, T., Günther, M., Martin, C., Pagès, G., Wolf, S.A., Kettenmann, H., Uckert, W., Niendorf, T. and Waiczies, S.
Molecular Cancer Therapeutics 15
(8): 1975-1987.
August 2016
Untersuchung des Farbsehens bei akuter einseitiger Neuritis nervi optici mittels eines webbasierten Farbsehtests [Investigation of color vision in acute unilateral optic neuritis using a web-based color vision test].
Kuchenbecker, J., Blum, M. and Paul, F.
Ophthalmologe 113
(3): 223-229.
March 2016
The structure of the mouse serotonin 5-HT3 receptor in lipid vesicles.
Kudryashev, M., Castaño-Díez, D., Deluz, C., Hassaine, G., Grasso, L., Graf-Meyer, A., Vogel, H. and Stahlberg, H.
Structure 24
(1): 165-170.
5 January 2016
Interindividual variation in DNA methylation at a putative POMC metastable epiallele is associated with obesity.
Kuehnen, P., Handke, D., Waterland, R.A., Hennig, B.J., Silver, M., Fulford, A.J., Dominguez-Salas, P., Moore, S.E., Prentice, A.M., Spranger, J., Hinney, A., Hebebrand, J., Heppner, F.L., Walzer, L., Groetzinger, C., Gromoll, J., Wiegand, S., Grueters, A. and Krude, H.
Cell Metabolism 24
(3): 502-509.
13 September 2016
The SIDER database of drugs and side effects.
Kuhn, M., Letunic, I., Jensen, L.J. and Bork, P.
Nucleic Acids Research 44
(D1): D1075-D1079.
4 January 2016
MOCAT2: a metagenomic assembly, annotation and profiling framework.
Kultima, J.R., Coelho, L.P., Forslund, K., Huerta-Cepas, J., Li, S.S., Driessen, M., Voigt, A.Y., Zeller, G., Sunagawa, S. and Bork, P.
Bioinformatics 32
(16): 2520-2523.
15 August 2016
Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin.
Kumar, S., Birol, M. and Miranker, A.D.
Chemical Communications 52
(38): 6391-6394.
11 May 2016
Foldamer-mediated manipulation of a pre-amyloid toxin.
Kumar, S., Birol, M., Schlamadinger, D.E., Wojcik, S.P., Rhoades, E. and Miranker, A.D.
Nature Communications 7
: 11412.
25 April 2016
Temporal modulation of collective cell behavior controls vascular network topology.
Kur, E., Kim, J., Tata, A., Comin, C.H., Harrington, K.I., Costa, L.d.F., Bentley, K. and Gu, C.
eLife 5
: e13212.
24 February 2016
Neural progenitors adopt specific identities by directly repressing all alternative progenitor transcriptional programs.
Kutejova, E., Sasai, N., Shah, A., Gouti, M. and Briscoe, J.
Developmental Cell 36
(6): 639-653.
21 March 2016
Novel ICD programming and inappropriate ICD therapy in CRT-D versus ICD patients: a MADIT-RIT sub-study.
Kutyifa, V., Daubert, J.P., Schuger, C., Goldenberg, I., Klein, H., Aktas, M.K., McNitt, S., Stockburger, M., Merkely, B., Zareba, W. and Moss, A.J.
Circulation Arrhythmia and Electrophysiology 9
(1): e001965.
January 2016
Hemodynamics and salt-and-water balance link sodium storage and vascular dysfunction in salt-sensitive subjects.
Laffer, C.L., Scott, R.C., Titze, J.M., Luft, F.C. and Elijovich, F.
Hypertension 68
(1): 195-203.
July 2016
Polyhydramnios, transient antenatal Bartter's syndrome, and MAGED2 mutations.
Laghmani, K., Beck, B.B., Yang, S.S., Seaayfan, E., Wenzel, A., Reusch, B., Vitzthum, H., Priem, D., Demaretz, S., Bergmann, K., Duin, L.K., Göbel, H., Mache, C., Thiele, H., Bartram, M.P., Dombret, C., Altmüller, J., Nürnberg, P., Benzing, T., Levtchenko, E., Seyberth, H.W., Klaus, G., Yigit, G., Lin, S.H., Timmer, A., de Koning, T.J., Scherjon, S.A., Schlingmann, K.P., Bertrand, M.J.M., Rinschen, M.M., de Backer, O., Konrad, M. and Kömhoff, M.
New England Journal of Medicine 374
(19): 1853-1863.
12 May 2016
A comprehensive comparison of general RNA-RNA interaction prediction methods.
Lai, D. and Meyer, I.M.
Nucleic Acids Research 44
(7): e61.
20 April 2016
Increased probability of co-occurrence of two rare diseases in consanguineous families and resolution of a complex phenotype by next generation sequencing.
Lal, D., Neubauer, B.A., Toliat, M.R., Altmüller, J., Thiele, H., Nürnberg, P., Kamrath, C., Schänzer, A., Sander, T., Hahn, A. and Nothnagel, M.
PLoS ONE 11
(1): e0146040.
January 2016
Evaluation of presumably disease causing SCN1A variants in a cohort of common epilepsy syndromes.
Lal, D., Reinthaler, E.M., Dejanovic, B., May, P., Thiele, H., Lehesjoki, A.E., Schwarz, G., Riesch, E., Ikram, M.A., van Duijn, C.M., Uitterlinden, A.G., Hofman, A., Steinböck, H., Gruber-Sedlmayr, U., Neophytou, B., Zara, F., Hahn, A., Gormley, P., Becker, F., Weber, Y.G., Cilio, M.R., Kunz, W.S., Krause, R., Zimprich, F., Lemke, J.R., Nürnberg, P., Sander, T., Lerche, H. and Neubauer, B.A.
PLoS ONE 11
(3): e0150426.
18 March 2016
GPU-accelerated level-set segmentation.
Lamas-Rodríguez, J., Heras, D.B., Argüello, F., Kainmueller, D., Zachow, S. and Bóo, M.
Journal of Real-Time Image Processing 12
(1): 15-29.
June 2016
Effects of Ncl. Basalis Meynert volume on the Trail-Making-Test are restricted to the left hemisphere.
Lammers, F., Mobascher, A., Musso, F., Shah, N.J., Warbrick, T., Zaborszky, L. and Winterer, G.
Brain and Behavior 6
(1): e00421.
January 2016
Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis.
Lange, C., Turrero Garcia, M., Decimo, I., Bifari, F., Eelen, G., Quaegebeur, A., Boon, R., Zhao, H., Boeckx, B., Chang, J., Wu, C., le Noble, F., Lambrechts, D., Dewerchin, M., Kuo, C.J., Huttner, W.B. and Carmeliet, P.
EMBO Journal 35
(9): 924-941.
2 May 2016
Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream.
Langenfurth, A., Gu, S., Bautze, V., Zhang, C., Neumann, J.E., Schüller, U., Stock, K., Wolf, S.A., Maier, A.M., Mastrella, G., Pak, A., Cheng, H., Kälin, R.E., Holmbeck, K., Strotmann, J., Kettenmann, H. and Glass, R.
Scientific Reports 6
: 32203.
30 August 2016
Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment.
Le, H.Q., Ghatak, S., Yeung, C.Y.C., Tellkamp, F., Günschmann, C., Dieterich, C., Yeroslaviz, A., Habermann, B., Pombo, A., Niessen, C.M. and Wickström, S.A.
Nature Cell Biology 18
(8): 864-875.
August 2016
Kcne2 deletion causes early-onset nonalcoholic fatty liver disease via iron deficiency anemia.
Lee, S.M., Nguyen, D., Anand, M., Kant, R., Koehncke, C., Lisewski, U., Roepke, T.K., Hu, Z. and Abbott, G.W.
Scientific Reports 6
: 23118.
17 March 2016
Generation of functional cardiomyocytes from the synoviocytes of patients with rheumatoid arthritis via induced pluripotent stem cells.
Lee, J., Jung, S.M., Ebert, A.D., Wu, H., Diecke, S., Kim, Y., Yi, H., Park, S.H. and Ju, J.H.
Scientific Reports 6
: 32669.
9 September 2016
Eradication of large solid tumors by gene therapy with a T cell receptor targeting a single cancer-specific point mutation.
Leisegang, M., Engels, B., Schreiber, K., Yew, P.Y., Kiyotani, K., Idel, C., Arina, A., Duraiswamy, J., Weichselbaum, R.R., Uckert, W., Nakamura, Y. and Schreiber, H.
Clinical Cancer Research 22
(11): 2734-2743.
1 June 2016
Targeting human melanoma neoantigens by T cell receptor gene therapy.
Leisegang, M., Kammertoens, T., Uckert, W. and Blankenstein, T.
Journal of Clinical Investigation 126
(3): 854-858.
1 March 2016
MACC1 induces tumor progression in transgenic mice and colorectal cancer patients via increased pluripotency markers Nanog and Oct4.
Lemos, C., Hardt, M.S., Juneja, M., Voss, C., Foerster, S., Jerchow, B., Haider, W., Blaker, H. and Stein, U.
Clinical Cancer Research 22
(11): 2812-2824.
1 June 2016
Age-dependent differential expression of death-associated protein 6 (Daxx) in various peripheral tissues and different brain regions of C57BL/6 male mice.
Lessard-Beaudoin, M., Laroche, M., Demers, M.J., Duclos, C., Denault, J.B., Grenier, G., Riechers, S.P., Wanker, E.E. and Graham, R.K.
Biogerontology 17
(5): 817-828.
November 2016
Organ-specific alteration in caspase expression and STK3 proteolysis during the aging process.
Lessard-Beaudoin, M., Laroche, M., Loudghi, A., Demers, M.J., Denault, J.B., Grenier, G., Riechers, S.P., Wanker, E.E. and Graham, R.K.
Neurobiology of Aging 47
: 50-62.
November 2016
Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees.
Letunic, I. and Bork, P.
Nucleic Acids Research 44
(W1): W242-W245.
8 July 2016
The PROMESA-protocol: progression rate of multiple system atrophy under EGCG supplementation as anti-aggregation-approach.
Levin, J., Maaß, S., Schuberth, M., Respondek, G., Paul, F., Mansmann, U., Oertel, W.H., Lorenzl, S., Krismer, F., Seppi, K., Poewe, W., Wenning, G., Giese, A., Boetzel, K. and Hoeglinger, G.
Journal of Neural Transmission 123
(4): 439-445.
April 2016
Survival of Igα-deficient mature B cells requires BAFF-R function.
Levit-Zerdoun, E., Becker, M., Pohlmeyer, R., Wilhelm, I., Maity, P.C., Rajewsky, K., Reth, M. and Hobeika, E.
Journal of Immunology 196
(5): 2348-2360.
1 March 2016
Durable coexistence of donor and recipient strains after fecal microbiota transplantation.
Li, S.S., Zhu, A., Benes, V., Costea, P.I., Hercog, R., Hildebrand, F., Huerta-Cepas, J., Nieuwdorp, M., Salojaervi, J., Voigt, A.Y., Zeller, G., Sunagawa, S., de Vos, W.M. and Bork, P.
Science 352
(6285): 586-589.
29 April 2016
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Li, S., Garrett-Bakelman, F.E., Chung, S.S., Sanders, M.A., Hricik, T., Rapaport, F., Patel, J., Dillon, R., Vijay, P., Brown, A.L., Perl, A.E., Cannon, J., Bullinger, L., Luger, S., Becker, M., Lewis, I.D., To, L.B., Delwel, R., Löwenberg, B., Döhner, H., Döhner, K., Guzman, M.L., Hassane, D.C., Roboz, G.J., Grimwade, D., Valk, P.J.M., D'Andrea, R.J., Carroll, M., Park, C.Y., Neuberg, D., Levine, R., Melnick, A.M. and Mason, C.E.
Nature Medicine 22
(7): 792-9.
July 2016
High-resolution expression map of the arabidopsis root reveals alternative splicing and lincRNA regulation.
Li, S., Yamada, M., Han, X., Ohler, U. and Benfey, P.N.
Developmental Cell 39
(4): 508-522.
21 November 2016
Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease patients reveals changes in genes associated with T cell receptor signaling.
Limbach, M., Saare, M., Tserel, L., Kisand, K., Eglit, T., Sauer, S., Axelsson, T., Syvänen, A.C., Metspalu, A., Milani, L. and Peterson, P.
Journal of Autoimmunity 67
: 46-56.
February 2016
Lowered pH leads to fusion peptide release and a highly dynamic intermediate of influenza hemagglutinin.
Lin, X.C., Noel, J.K., Wang, Q.H., Ma, J.P. and Onuchic, J.N.
Journal of Physical Chemistry B 120
(36): 9654-9660.
15 September 2016
Extending the dynamic range in metabolomics experiments by automatic correction of peaks exceeding the detection limit.
Lisec, J., Hoffmann, F., Schmitt, C. and Jaeger, C.
Analytical Chemistry 88
(15): 7487-7492.
2 August 2016
Increased aldosterone-dependent Kv1.5 recycling predisposes to pacing-induced atrial fibrillation in Kcne3-/- mice.
Lisewski, U., Koehncke, C., Wilck, N., Buschmeyer, B., Pieske, B. and Roepke, T.K.
FASEB Journal 30
(7): 2476-2489.
July 2016
Targeting of the Plzf gene in the rat by transcription activator-like effector nuclease results in caudal regression syndrome in spontaneously hypertensive rats.
Liška, F., Peterková, R., Peterka, M., Landa, V., Zidek, V., Mlejnek, P., Šilhavý, J., Šimáková, M., Křen, V., Starker, C.G., Voytas, D.F., Izsvák, Z. and Pravenec, M.
PLoS ONE 11
(10): e0164206.
11 October 2016
Bacterial antisense RNAs are mainly the product of transcriptional noise.
Llorens-Rico, V., Cano, J., Kamminga, T., Gil, R., Latorre, A., Chen, W.H., Bork, P., Glass, J.I., Serrano, L. and Lluch-Senar, M.
Science Advances 2
(3): e1501363.
4 March 2016
Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.
Lodka, D., Pahuja, A., Geers-Knörr, C., Scheibe, R., Nowak, M., Hamati, J., Köhncke, C., Purfürst, B., Kanashova, T., Schmidt, S., Glass, D.J., Morano, I., Heuser, A., Kraft, T., Bassel-Duby, R., Olson, E.N., Dittmar, G., Sommer, T. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7
(2): 165-180.
May 2016
Minichromosome maintenance complex is a critical node in the miR-183 signaling network of MYCN-amplified neuroblastoma cells.
Lodrini, M., Poschmann, G., Schmidt, V., Wünschel, J., Dreidax, D., Witt, O., Höfer, T., Meyer, H.E., Stühler, K., Eggert, A. and Deubzer, H.E.
Journal of Proteome Research 15
(7): 2178-2186.
1 July 2016
Identification of novel genetic causes of Rett syndrome-like phenotypes.
Lopes, F., Barbosa, M., Ameur, A., Soares, G., de Sá, J., Dias, A.I., Oliveira, G., Cabral, P., Temudo, T., Calado, E., Cruz, I.F., Vieira, J.P., Oliveira, R., Esteves, S., Sauer, S., Jonasson, I., Syvänen, A.C., Gyllensten, U., Pinto, D. and Maciel, P.
Journal of Medical Genetics 53
(3): 190-199.
March 2016
Different promoter affinities account for specificity in MYC-dependent gene regulation.
Lorenzin, F., Benary, U., Baluapuri, A., Walz, S., Jung, L.A., von Eyss, B., Kisker, C., Wolf, J., Eilers, M. and Wolf, E.
eLife 5
: e15161.
27 July 2016
Diagnostic and prognostic potential of circulating cell-free genomic and mitochondrial DNA fragments in clear cell renal cell carcinoma patients.
Lu, H., Busch, J., Jung, M., Rabenhorst, S., Ralla, B., Kilic, E., Mergemeier, S., Budach, N., Fendler, A. and Jung, K.
Clinica Chimica Acta 452
: 109-119.
15 January 2016
In vivo and in vitro effects of multiple sclerosis immunomodulatory therapeutics on glutamatergic excitotoxicity.
Luchtman, D., Gollan, R., Ellwardt, E., Birkenstock, J., Robohm, K., Siffrin, V. and Zipp, F.
Journal of Neurochemistry 136
(5): 971-980.
March 2016
Einfluss genetischer Varianten auf die humane Erythropoese [Influence of genetic variants on human erythropoiesis].
Ludwig, L.S.
BIOspektrum 22
(7): 768-769.
November 2016
Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers.
Lueck, S.C., Russ, A.C., Botzenhardt, U., Schlenk, R.F., Zobel, K., Deshayes, K., Vucic, D., Döhner, H., Döhner, K., Fulda, S. and Bullinger, L.
Oncotarget 7
(31): 49539-49551.
2 August 2016
Efficient application of de novo RNA assemblers for proteomics informed by transcriptomics.
Luge, T., Fischer, C. and Sauer, S.
Journal of Proteome Research 15
(10): 3938-3943.
7 October 2016
Generating sample-specific databases for mass spectrometry-based proteomic analysis by using RNA sequencing.
Luge, T. and Sauer, S.
Methods in Molecular Biology 1394
: 219-232.
2016
A novel splicing mutation in the IQSEC2 gene that modulates the phenotype severity in a family with intellectual disability.
Madrigal, I., Alvarez-Mora, M.I., Rosell, J., Rodríguez-Revenga, L., Karlberg, O., Sauer, S., Syvänen, A.C. and Mila, M.
European Journal of Human Genetics 24
(8): 1117-1123.
August 2016
Chronic allergic pulmonary inflammation is aggravated in angiotensin-(1-7) Mas receptor knockout mice.
Magalhaes, G.S., Rodrigues-Machado, M.G., Motta-Santos, D., Alenina, N., Bader, M., Santos, R.A.S., Barcelos, L.S. and Campagnole-Santos, M.J.
American Journal of Physiology Lung Cellular and Molecular Physiology 311
(6): L1141-L1148.
12 December 2016
Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.
Magarin, M., Pohl, T., Lill, A., Schulz, H., Blaschke, F., Heuser, A., Thierfelder, L., Donath, S. and Drenckhahn, J.D.
Journal of Molecular and Cellular Cardiology 97
: 1-14.
August 2016
Transcriptional profiling of regenerating embryonic mouse hearts.
Magarin, M., Schulz, H., Thierfelder, L. and Drenckhahn, J.D.
Genomics Data 9
: 145-147.
September 2016
Nuclear translocation of the cardiac L-type calcium channel C-terminus is regulated by sex and 17β-estradiol.
Mahmoodzadeh, S., Haase, H., Sporbert, A., Rharass, T., Panáková, D. and Morano, I.
Journal of Molecular and Cellular Cardiology 97
: 226-234.
August 2016
Effects of the lercanidipine-enalapril combination vs. the corresponding monotherapies on home blood pressure in hypertension: evidence from a large database.
Mancia, G., Omboni, S., Chazova, I., Coca, A., Girerd, X., Haller, H., Parati, G., Pauletto, P., Pupek-Musialik, D. and Svyshchenko, Y.
Journal of Hypertension 34
(1): 139-148.
January 2016
Human engineered heart tissue: analysis of contractile force.
Mannhardt, I., Breckwoldt, K., Letuffe-Brenière, D., Schaaf, S., Schulz, H., Neuber, C., Benzin, A., Werner, T., Eder, A., Schulze, T., Klampe, B., Christ, T., Hirt, M.N., Huebner, N., Moretti, A., Eschenhagen, T. and Hansen, A.
Stem Cell Reports 7
(1): 29-42.
12 July 2016
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri, L., Noerenberg, D., Young, E., Mylonas, E., Abdulla, M., Frick, M., Asmar, F., Ljungstroem, V., Schneider, M., Yoshida, K., Skaftason, A., Pandzic, T., Gonzalez, B., Tasidou, A., Waldhueter, N., Rivas-Delgado, A., Angelopoulou, M., Ziepert, M., Arends, C.M., Couronne, L., Lenze, D., Baldus, C.D., Bastard, C., Okosun, J., Fitzgibbon, J., Doerken, B., Drexler, H.G., Roos-Weil, D., Schmitt, C.A., Munch-Petersen, H.D., Zenz, T., Hansmann, M.L., Strefford, J.C., Enblad, G., Bernard, O.A., Ralfkiaer, E., Erlanson, M., Korkolopoulou, P., Hultdin, M., Papadaki, T., Gronbaek, K., Lopez-Guillermo, A., Ogawa, S., Kueppers, R., Stamatopoulos, K., Stavroyianni, N., Kanellis, G., Rosenwald, A., Campo, E., Amini, R.M., Ott, G., Vassilakopoulos, T.P., Hummel, M., Rosenquist, R. and Damm, F.
Blood 128
(23): 2666-2670.
15 December 2016
A complex water network contributes to high-affinity binding in an antibody-antigen interface.
Marino, S.F., Olal, D. and Daumke, O.
Data in Brief 6
: 394-397.
March 2016
Role of cystathionine gamma-lyase in immediate renal impairment and inflammatory response in acute ischemic kidney injury.
Markó, L., Szijártó, I.A., Filipovic, M.R., Kaßmann, M., Balogh, A., Park, J.K., Przybyl, L., N'diaye, G., Krämer, S., Anders, J., Ishii, I., Müller, D.N. and Gollasch, M.
Scientific Reports 6
: 27517.
8 June 2016
Tubular epithelial NF-κB activity regulates ischemic AKI.
Markó, L., Vigolo, E., Hinze, C., Park, J.K., Roël, G., Balogh, A., Choi, M., Wübken, A., Cording, J., Blasig, I.E., Luft, F.C., Scheidereit, C., Schmidt-Ott, K.M., Schmidt-Ullrich, R. and Müller, D.N.
Journal of the American Society of Nephrology 27
(9): 2658-2669.
September 2016
Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study.
Martinez-Lapiscina, E.H., Arnow, S., Wilson, J.A., Saidha, S., Preiningerova, J.L., Oberwahrenbrock, T., Brandt, A.U., Pablo, L.E., Guerrieri, S., Gonzalez, I., Outteryck, O., Mueller, A.K., Albrecht, P., Chan, W., Lukas, S., Balk, L.J., Fraser, C., Frederiksen, J.L., Resto, J., Frohman, T., Cordano, C., Zubizarreta, I., Andorra, M., Sanchez-Dalmau, B., Saiz, A., Bermel, R., Klistorner, A., Petzold, A., Schippling, S., Costello, F., Aktas, O., Vermersch, P., Oreja-Guevara, C., Comi, G., Leocani, L., Garcia-Martin, E., Paul, F., Havrdova, E., Frohman, E., Balcer, L.J., Green, A.J., Calabresi, P.A. and Villoslada, P.
Lancet Neurology 15
(6): 574-584.
May 2016
Microglia development follows a stepwise program to regulate brain homeostasis.
Matcovitch-Natan, O., Winter, D.R., Giladi, A., Vargas Aguilar, S., Spinrad, A., Sarrazin, S., Ben-Yehuda, H., David, E., Zelada González, F., Perrin, P., Keren-Shaul, H., Gury, M., Lara-Astaiso, D., Thaiss, C.A., Cohen, M., Bahar Halpern, K., Baruch, K., Deczkowska, A., Lorenzo-Vivas, E., Itzkovitz, S., Elinav, E., Sieweke, M.H., Schwartz, M. and Amit, I.
Science 353
(6301): aad8670.
19 August 2016
Hodgkin lymphoma: pathology and biology.
Mathas, S., Hartmann, S. and Küppers, R.
Seminars in Hematology 53
(3): 139-147.
July 2016
Weight loss partially restores glucose-driven betatrophin response in humans.
Maurer, L., Brachs, S., Decker, A.M., Brachs, M., Leupelt, V., Jumpertz von Schwartzenberg, R., Ernert, A., Bobbert, T., Krude, H., Spranger, J. and Mai, K.
Journal of Clinical Endocrinology and Metabolism 101
(11): 4014-4020.
November 2016
An integer programming framework for inferring disease complexes from network data.
Mazza, A., Klockmeier, K., Wanker, E. and Sharan, R.
Bioinformatics 32
(12): i271-i277.
15 June 2016
The activation of OR51E1 causes growth suppression of human prostate cancer cells.
Maßberg, D., Jovancevic, N., Offermann, A., Simon, A., Baniahmad, A., Perner, S., Pungsrinont, T., Luko, K., Philippou, S., Ubrig, B., Heiland, M., Weber, L., Altmüller, J., Becker, C., Gisselmann, G., Gelis, L. and Hatt, H.
Oncotarget 7
(30): 48231-48249.
26 July 2016
Kinetic analysis of protein stability reveals age-dependent degradation.
McShane, E., Sin, C., Zauber, H., Wells, J.N., Donnelly, N., Wang, X., Hou, J., Chen, W., Storchova, Z., Marsh, J.A., Valleriani, A. and Selbach, M.
Cell 167
(3): 803-815.
20 October 2016
Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism.
Meiser, J., Delcambre, S., Wegner, A., Jaeger, C., Ghelfi, J., D'Herouel, A.F., Dong, X., Weindl, D., Stautner, C., Nonnenmacher, Y., Michelucci, A., Popp, O., Giesert, F., Schildknecht, S., Kraemer, L., Schneider, J.G., Woitalla, D., Wurst, W., Skupin, A., Weisenhorn, D.M.V., Krueger, R., Leist, M. and Hiller, K.
Neurobiology of Disease 89
: 112-125.
May 2016
Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA.
Mensali, N., Ying, F., Sheng, V.O.Y., Yang, W., Walseng, E., Kumari, S., Fallang, L.E., Kolstad, A., Uckert, W., Malmberg, K.J., Waelchli, S. and Olweus, J.
OncoImmunology 5
(5): e1138199.
18 February 2016
Omentin-1 and risk of myocardial infarction and stroke: results from the EPIC-Potsdam cohort study.
Menzel, J., di Giuseppe, R., Biemann, R., Wittenbecher, C., Aleksandrova, K., Pischon, T., Fritsche, A., Schulze, M.B., Boeing, H., Isermann, B. and Weikert, C.
Atherosclerosis 251
: 415-421.
August 2016
Proteogenomics connects somatic mutations to signalling in breast cancer.
Mertins, P., Mani, D.R., Ruggles, K.V., Gillette, M.A., Clauser, K.R., Wang, P., Wang, X., Qiao, J.W., Cao, S., Petralia, F., Kawaler, E., Mundt, F., Krug, K., Tu, Z., Lei, J.T., Gatza, M.L., Wilkerson, M., Perou, C.M., Yellapantula, V., Huang, K.L., Lin, C., McLellan, M.D., Yan, P., Davies, S.R., Townsend, R.R., Skates, S.J., Wang, J., Zhang, B., Kinsinger, C.R., Mesri, M., Rodriguez, H., Ding, L., Paulovich, A.G., Fenyoe, D., Ellis, M.J. and Carr, S.A.
Nature 534
(7605): 55-62.
2 June 2016
Specific metabolic markers are associated with future waist-gaining phenotype in women.
Merz, B., Nöthlings, U., Wahl, S., Haftenberger, M., Schienkiewitz, A., Adamski, J., Suhre, K., Wang-Sattler, R., Grallert, H., Thorand, B., Pischon, T., Bachlechner, U., Floegel, A., Peters, A. and Boeing, H.
PLoS ONE 11
(6): e0157733.
20 June 2016
Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis.
Metz, I., Beißbarth, T., Ellenberger, D., Pache, F., Stork, L., Ringelstein, M., Aktas, O., Jarius, S., Wildemann, B., Dihazi, H., Friede, T., Brück, W., Ruprecht, K. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 3
(2): e204.
April 2016
Autoantibodies to tetraspanins (CD9, CD81 and CD82) in demyelinating diseases.
Miyaji, K., Paul, F., Shahrizaila, N., Umapathi, T. and Yuki, N.
Journal of Neuroimmunology 291
: 78-81.
15 February 2016
Association of common polymorphisms in the nicotinic acetylcholine receptor alpha4 subunit gene with an electrophysiological endophenotype in a large population-based sample.
Mobascher, A., Diaz-Lacava, A., Wagner, M., Gallinat, J., Wienker, T.F., Drichel, D., Becker, T., Steffens, M., Dahmen, N., Gruender, G., Thuerauf, N., Kiefer, F., Kornhuber, J., Toliat, M.R., Thiele, H., Nuernberg, P., Steinlein, O. and Winterer, G.
PLoS ONE 11
(4): e0152984.
7 April 2016
Ly6C(hi) monocytes provide a link between antibiotic-induced changes in gut microbiota and adult hippocampal neurogenesis.
Moehle, L., Mattei, D., Heimesaat, M.M., Bereswill, S., Fischer, A., Alutis, M., French, T., Hambardzumyan, D., Matzinger, P., Dunay, I.R. and Wolf, S.A.
Cell Reports 15
(9): 1945-1956.
31 May 2016
Effects of silibinin on growth and invasive properties of human ovarian carcinoma cells through suppression of heregulin/HER3 pathway.
Momeny, M., Ghasemi, R., Valenti, G., Miranda, M., Zekri, A., Zarrinrad, G., Javadikooshesh, S., Yaghmaie, M., Alimoghaddam, K., Ghavamzadeh, A. and Ghaffari, S.H.
Tumor Biology 37
(3): 3913-3923.
March 2016
Novel IFT122 mutations in three Argentinian patients with cranioectodermal dysplasia: expanding the mutational spectrum.
Moosa, S., Obregon, M.G., Altmüller, J., Thiele, H., Nürnberg, P., Fano, V. and Wollnik, B.
American Journal of Medical Genetics Part A 170
(5): 1295-1301.
May 2016
Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas.
Morales, M.G., Abrigo, J., Acuna, M.J., Santos, R.A., Bader, M., Brandan, E., Simonetta, F., Olguin, H., Cabrera, D. and Cabello-Verrugio, C.
Disease Models & Mechanisms 9
(4): 441-449.
1 April 2016
A molecular signature of myalgia in myotonic dystrophy 2.
Moshourab, R., Palada, V., Grunwald, S., Grieben, U., Lewin, G.R. and Spuler, S.
EBioMedicine 7
: 205-211.
May 2016
Measurement of vibration detection threshold and tactile spatial acuity in human subjects.
Moshourab, R., Frenzel, H., Lechner, S., Haseleu, J., Bégay, V., Omerbašić, D. and Lewin, G.R.
Journal of Visualized Experiments
(115): e52966.
1 September 2016
Effects of ACE2 deficiency on physical performance and physiological adaptations of cardiac and skeletal muscle to exercise.
Motta-Santos, D., Dos Santos, R.A.S., Oliveira, M., Qadri, F., Poglitsch, M., Mosienko, V., Kappes Becker, L., Campagnole-Santos, M.J., Penninger, J.M., Alenina, N. and Bader, M.
Hypertension Research 39
(7): 506-512.
July 2016
ANGIOGENES: knowledge database for protein-coding and noncoding RNA genes in endothelial cells.
Mueller, R., Weirick, T., John, D., Militello, G., Chen, W., Dimmeler, S. and Uchida, S.
Scientific Reports 6
: 32475.
1 September 2016
Demonstration of the functional impact of vasopressin signaling in the thick ascending limb by a targeted transgenic rat approach.
Mutig, K., Borowski, T., Boldt, C., Borschewski, A., Paliege, A., Popova, E., Bader, M. and Bachmann, S.
American Journal of Physiology Renal Physiology 311
(2): F411-F423.
1 August 2016
Cardiomyocyte-derived CXCL12 is not involved in cardiogenesis but plays a crucial role in myocardial infarction.
Mühlstedt, S., Ghadge, S.K., Duchene, J., Qadri, F., Järve, A., Vilianovich, L., Popova, E., Pohlmann, A., Niendorf, T., Boyé, P., Özcelik, C. and Bader, M.
Journal of Molecular Medicine 94
(9): 1005-1014.
September 2016
Dissecting the effect of genetic variation on the hepatic expression of drug disposition genes across the collaborative cross mouse strains.
Nachshon, A., Abu-Toamih Atamni, H.J., Steuerman, Y., Sheikh-Hamed, R., Dorman, A., Mott, R., Dohm, J.C., Lehrach, H., Sultan, M., Shamir, R., Sauer, S., Himmelbauer, H., Iraqi, F.A. and Gat-Viks, I.
Frontiers in Genetics 7
: 172.
5 October 2016
Zerebrale Gadoliniumablagerungen bei der Magnetresonanztomographie des Herzens: Stellungnahme der Deutschen Gesellschaft für Kardiologie - Herz- und Kreislaufforschung [Cerebral gadolinium deposits in magnetic resonance imaging of the heart: statement of the German Cardiac Society].
Nagel, E., Lotz, J., Schulz-Menger, J., Bruder, O., Muellerleile, K., Schwaiger, M., Bengel, F., Kelle, S., Steen, H. and Vogl, T.J.
Kardiologe 10
(6): 371-373.
December 2016
Identification of novel regulators of developmental hematopoiesis using endoglin regulatory elements as molecular probes.
Nasrallah, R., Fast, E.M., Solaimani, P., Knezevic, K., Eliades, A., Patel, R., Thambyrajah, R., Unnikrishnan, A., Thoms, J., Beck, D., Vink, C.S., Smith, A., Wong, J., Shepherd, M., Kent, D., Roychoudhuri, R., Paul, F., Klippert, J., Hammes, A., Willnow, T., Göttgens, B., Dzierzak, E., Zon, L.I., Lacaud, G., Kouskoff, V. and Pimanda, J.E.
Blood 128
(15): 1928-1939.
13 October 2016
IFNs modify the proteome of Legionella-containing vacuoles and restrict infection via IRG1-derived itaconic acid.
Naujoks, J., Tabeling, C., Dill, B.D., Hoffmann, C., Brown, A.S., Kunze, M., Kempa, S., Peter, A., Mollenkopf, H.J., Dorhoi, A., Kershaw, O., Gruber, A.D., Sander, L.E., Witzenrath, M., Herold, S., Nerlich, A., Hocke, A.C., van Driel, I., Suttorp, N., Bedoui, S., Hilbi, H., Trost, M. and Opitz, B.
PLoS Pathogens 12
(2): e1005408.
1 February 2016
cAMP-dependent protein kinase A (PKA) regulates angiogenesis by modulating tip cell behavior in a Notch-independent manner.
Nedvetsky, P.I., Zhao, X., Mathivet, T., Aspalter, I.M., Stanchi, F., Metzger, R.J., Mostov, K.E. and Gerhardt, H.
Development 143
(19): 3582-3590.
4 October 2016
Flow cytometric analysis of T cell/monocyte ratio in clinically isolated syndrome identifies patients at risk of rapid disease progression.
Nemecek, A., Zimmermann, H., Rübenthaler, J., Fleischer, V., Paterka, M., Luessi, F., Müller-Forell, W., Zipp, F. and Siffrin, V.
Multiple Sclerosis Journal 22
(4): 483-493.
April 2016
Diagnostik, Therapie und Verlaufskontrolle des Diabetes mellitus im Kindes- und Jugendalter - AWMF-Registernummer 057-016 [Diagnosis, therapy and follow-up of diabetes mellitus in children and adolescents - AWMF-Registry-Number 057-016].
Neu, A., Buerger-Buesing, J., Danne, T., Dost, A., Holder, M., Holl, R.W., Holterhus, P.M., Kapellen, T., Karges, B., Kordonouri, O., Mueller, S., Raile, K., Schweizer, R., von Sengbusch, S., Stachow, R., Wagner, V., Wiegand, S. and Ziegler, R.
Diabetologie und Stoffwechsel 11
(1): 35-94.
25 February 2016
BCR-ABL-positive acute myeloid leukemia: a new entity? Analysis of clinical and molecular features.
Neuendorff, N.R., Burmeister, T., Doerken, B. and Westermann, J.
Annals of Hematology 95
(8): 1211-1221.
August 2016
Health-related quality of life in children and adolescents with hereditary bleeding disorders and in children and adolescents with stroke: cross-sectional comparison to siblings and peers.
Neuner, B., von Mackensen, S., Holzhauer, S., Funk, S., Klamroth, R., Kurnik, K., Kruempel, A., Halimeh, S., Reinke, S., Fruehwald, M. and Nowak-Goettl, U.
BioMed Research International 2016
: 1579428.
15 May 2016
CCL4 as an adjuvant for DNA vaccination in a Her2/neu mouse tumor model.
Nguyen-Hoai, T., Pham-Duc, M., Gries, M., Dörken, B., Pezzutto, A. and Westermann, J.
Cancer Gene Therapy 23
(6): 162-167.
June 2016
Obesity biomarkers, metabolism and risk of cancer: an epidemiological perspective.
Nimptsch, K. and Pischon, T.
Recent Results in Cancer Research 208
(208): 199-217.
2 December 2016
Obesity and oesophageal cancer.
Nimptsch, K., Steffen, A. and Pischon, T.
Recent Results in Cancer Research 208
(208): 67-80.
2 December 2016
Habitual intake of flavonoid subclasses and risk of colorectal cancer in 2 large prospective cohorts.
Nimptsch, K., Zhang, X., Cassidy, A., Song, M., O'Reilly, É.J., Lin, J.H., Pischon, T., Rimm, E.B., Willett, W.C., Fuchs, C.S., Ogino, S., Chan, A.T., Giovannucci, E.L. and Wu, K.
American Journal of Clinical Nutrition 103
(1): 184-191.
January 2016
SMOG 2: A versatile software package for generating structure-based models.
Noel, J.K., Levi, M., Raghunathan, M., Lammert, H., Hayes, R.L., Onuchic, J.N. and Whitford, P.C.
PLoS Computational Biology 12
(3): e1004794.
10 March 2016
How EF-Tu can contribute to efficient proofreading of aa-tRNA by the ribosome.
Noel, J.K. and Whitford, P.C.
Nature Communications 7
: 13314.
31 October 2016
Gut microbiota linked to sexual preference and HIV infection.
Noguera-Julian, M., Rocafort, M., Guillen, Y., Rivera, J., Casadella, M., Nowak, P., Hildebrand, F., Zeller, G., Parera, M., Bellido, R., Rodriguez, C., Carrillo, J., Mothe, B., Coll, J., Bravo, I., Estany, C., Herrero, C., Saz, J., Sirera, G., Torrela, A., Navarro, J., Crespo, M., Brander, C., Negredo, E., Blanco, J., Guarner, F., Calle, M.L., Bork, P., Soennerborg, A., Clotet, B. and Paredes, R.
EBioMedicine 5
: 135-146.
March 2016
Increased adult neurogenesis in mice with a permanent overexpression of the postsynaptic 5-HT1A receptor.
Noto, B., Klempin, F., Alenina, N., Bader, M., Fink, H. and Sander, S.E.
Neuroscience Letters 633
: 246-251.
28 October 2016
Aberrant expression of miR-9/9* in myeloid progenitors inhibits neutrophil differentiation by post-transcriptional regulation of ERG.
Nowek, K., Sun, S.M., Bullinger, L., Bindels, E.M.J., Exalto, C., Dijkstra, M.K., van Lom, K., Döhner, H., Erkeland, S.J., Löwenberg, B. and Jongen-Lavrencic, M.
Leukemia 30
(1): 229-37.
January 2016
Expression of a passenger miR-9* predicts favorable outcome in adults with acute myeloid leukemia less than 60 years of age.
Nowek, K., Sun, S.M., Dijkstra, M.K., Bullinger, L., Döhner, H., Erkeland, S.J., Löwenberg, B. and Jongen-Lavrencic, M.
Leukemia 30
(2): 303-9.
February 2016
Aging increases susceptibility to high fat diet-induced metabolic syndrome in C57BL/6 mice: Improvement in glycemic and lipid profile after antioxidant therapy.
Nunes-Souza, V., Cesar-Gomes, C.J., da Fonseca, L.J.S., da Silva Guedes, G., Smaniotto, S. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2016
: 1987960.
2016
CD36/sirtuin 1 axis impairment contributes to hepatic steatosis in ACE2-deficient mice.
Nunes-Souza, V., Alenina, N., Qadri, F., Penninger, J.M., Santos, R.A.S., Bader, M. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2016
: 6487509.
2016
16-channel bow tie antenna transceiver array for cardiac MR at 7.0 Tesla.
Oezerdem, C., Winter, L., Graessl, A., Paul, K., Els, A., Weinberger, O., Rieger, J., Kuehne, A., Dieringer, M., Hezel, F., Voit, D., Frahm, J. and Niendorf, T.
Magnetic Resonance in Medicine 75
(6): 2553-2565.
June 2016
Locus coeruleus dysfunction in transgenic rats with low brain angiotensinogen.
Ogier, M., Bricca, G., Bader, M. and Bezin, L.
CNS Neuroscience & Therapeutics 22
(3): 230-237.
March 2016
Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation.
Olal, D. and Daumke, O.
Cell Reports 14
(9): 2092-2099.
8 March 2016
Hypofunctional TrkA accounts for the absence of pain sensitization in the African naked mole-rat.
Omerbašić, D., Smith, E.S.J., Moroni, M., Homfeld, J., Eigenbrod, O., Bennett, N.C., Reznick, J., Faulkes, C.G., Selbach, M. and Lewin, G.R.
Cell Reports 17
(3): 748-758.
11 October 2016
Spatiotemporal variation of mammalian protein complex stoichiometries.
Ori, A., Iskar, M., Buczak, K., Kastritis, P., Parca, L., Andres-Pons, A., Singer, S., Bork, P. and Beck, M.
Genome Biology 17
(1): 47.
14 March 2016
Tissue-specific DNA demethylation is required for proper B-cell differentiation and function.
Orlanski, S., Labi, V., Reizel, Y., Spiro, A., Lichtenstein, M., Levin-Klein, R., Koralov, S.B., Skversky, Y., Rajewsky, K., Cedar, H. and Bergman, Y.
Proceedings of the National Academy of Sciences of the United States of America 113
(18): 5018-5023.
3 May 2016
Improved treatment of MT-3 breast cancer and brain metastases in a mouse xenograft by LRP-targeted oxaliplatin liposomes.
Orthmann, A., Peiker, L., Fichtner, I., Hoffmann, A., Hilger, R.A. and Zeisig, R.
Journal of Biomedical Nanotechnology 12
(1): 56-68.
January 2016
Heterogeneous mechanisms of primary and acquired resistance to third-generation EGFR inhibitors.
Ortiz-Cuaran, S., Scheffler, M., Plenker, D., Dahmen, L., Scheel, A.H., Fernandez-Cuesta, L., Meder, L., Lovly, C.M., Persigehl, T., Merkelbach-Bruse, S., Bos, M., Michels, S., Fischer, R., Albus, K., König, K., Schildhaus, H.U., Fassunke, Jana, Ihle, M.A., Pasternack, H., Heydt, C., Becker, C., Altmüller, J., Ji, H., Müller, C., Florin, A., Heuckmann, J.M., Nuernberg, P., Ansén, S., Heukamp, L.C., Berg, J., Pao, W., Peifer, M., Buettner, R., Wolf, J., Thomas, R.K. and Sos, M.L.
Clinical Cancer Research 22
(19): 4837-4847.
2 October 2016
Accuracy and reliability of the kinect version 2 for clinical measurement of motor function.
Otte, K., Kayser, B., Mansow-Model, S., Verrel, J., Paul, F., Brandt, A.U. and Schmitz-Hübsch, T.
PLoS ONE 11
(11): e0166532.
18 November 2016
Brain parenchymal damage in neuromyelitis optica spectrum disorder - a multimodal MRI study.
Pache, F., Zimmermann, H., Finke, C., Lacheta, A., Papazoglou, S., Kuchling, J., Wuerfel, J., Hamm, B., Ruprecht, K., Paul, F., Brandt, A.U. and Scheel, M.
European Radiology 26
(12): 4413-4422.
December 2016
MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients.
Pache, F., Zimmermann, H., Mikolajczak, J., Schumacher, S., Lacheta, A., Oertel, F.C., Bellmann-Strobl, J., Jarius, S., Wildemann, B., Reindl, M., Waldman, A., Soelberg, K., Asgari, N., Ringelstein, M., Aktas, O., Gross, N., Buttmann, Ma., Ach, T., Ruprecht, K., Paul, F. and Brandt, A.U.
Journal of Neuroinflammation 13
(1): 282.
1 November 2016
Bacterial toxins for oncoleaking suicidal cancer gene therapy.
Pahle, J. and Walther, W.
Recent Results in Cancer Research 209
: 95-110.
2016
The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in stroke and Alzheimer's disease.
Pannell, M., Meier, M.A., Szulzewsky, F., Matyash, V., Endres, M., Kronenberg, G., Prinz, V., Waiczies, S., Wolf, S.A. and Kettenmann, H.
Brain Structure & Function 221
(2): 1157-1172.
March 2016
Genomic classification and prognosis in acute myeloid leukemia.
Papaemmanuil, E., Gerstung, M., Bullinger, L., Gaidzik, V.I., Paschka, P., Roberts, N.D., Potter, N.E., Heuser, M., Thol, F., Bolli, N., Gundem, G., Van Loo, P., Martincorena, I., Ganly, P., Mudie, L., McLaren, S., O'Meara, S., Raine, K., Jones, D.R., Teague, J.W., Butler, A.P., Greaves, M.F., Ganser, A., Döhner, K., Schlenk, R.F., Döhner, H. and Campbell, P.J.
New England Journal of Medicine 374
(23): 2209-2221.
12 July 2016
Gatekeeper role of brain antigen-presenting CD11c(+) cells in neuroinflammation.
Paterka, M., Siffrin, V., Voss, J.O., Werr, J., Hoppmann, N., Gollan, R., Belikan, P., Bruttger, J., Birkenstock, J., Jung, S., Esplugues, E., Yogev, N., Flavell, R.A., Bopp, T. and Zipp, F.
EMBO Journal 35
(1): 89-101.
4 January 2016
Human gut microbes impact host serum metabolome and insulin sensitivity.
Pedersen, H.K., Gudmundsdottir, V., Nielsen, H.B., Hyotylainen, T., Nielsen, T., Jensen, B.A.H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., Le Chatelier, E., Levenez, F., Doré, J., Mattila, I., Plichta, D.R., Pöhö, P., Hellgren, L.I., Arumugam, M., Sunagawa, S., Vieira-Silva, S., Jørgensen, T., Holm, J.B., Trošt, K., Kristiansen, K., Brix, S., Raes, J., Wang, J., Hansen, T., Bork, P., Brunak, S., Oresic, M., Ehrlich, S.D. and Pedersen, O.
Nature 535
(7612): 376-381.
21 July 2016
Mutations in NEBL encoding the cardiac Z-disk protein nebulette are associated with various cardiomyopathies.
Perrot, A., Tomasov, P., Villard, E., Faludi, R., Melacini, P., Lossie, J., Lohmann, N., Richard, P., De Bortoli, M., Angelini, A., Varga-Szemes, A., Sperling, S.R., Simor, T., Veselka, J., Oezcelik, C. and Charron, P.
Archives of Medical Science 12
(2): 263-278.
April 2016
A complex of Htm1 and the oxidoreductase Pdi1 accelerates degradation of misfolded glycoproteins.
Pfeiffer, A., Stephanowitz, H., Krause, E., Volkwein, C., Hirsch, C., Jarosch, E. and Sommer, T.
Journal of Biological Chemistry 291
(23): 12195-12207.
3 June 2016
Imprinting of skin/inflammation homing in CD4+ T cells is controlled by DNA methylation within the fucosyltransferase 7 gene.
Pink, M., Ratsch, B.A., Mardahl, M., Durek, P., Polansky, J.K., Karl, M., Baumgrass, R., Wallner, S., Cadenas, C., Gianmoena, K., Floess, S., Chen, W., Nordstroem, K., Tierling, S., Olek, S., Walter, J., Hamann, A. and Syrbe, U.
Journal of Immunology 197
(8): 3406-3414.
15 October 2016
Increased periodontal attachment loss in patients with systemic sclerosis.
Pischon, N., Hoedke, D., Kurth, S., Lee, P., Dommisch, H., Steinbrecher, A., Pischon, T., Burmester, G.R., Buttgereit, F., Detert, J. and Riemekasten, G.
Journal of Periodontology 87
(7): 763-771.
July 2016
Obesity and risk of cancer: an introductory overview.
Pischon, T. and Nimptsch, K.
Recent Results in Cancer Research 208
(208): 1-15.
2 December 2016
Psychiatrische und soziale Aspekte bei Patienten mit fragilem X-Syndrom (FRX) [Psychiatric and social aspects of patients with fragile X Syndrome].
Pittrow, D., Gaese, F., Colla, M., Huss, M., Kretschmar, C., Brinkman, M., Peters, H., Elstner, S., Weirich, S. and Haessler, F.
Psychiatrische Praxis 43
(3): 160-164.
April 2016
Data of oxygen- and pH-dependent oxidation of resveratrol.
Plauth, A., Geikowski, A., Cichon, S., Wowro, S.J., Liedgens, L., Rousseau, M., Weidner, C., Fuhr, L., Kliem, M., Jenkins, G., Lotito, S., Wainwright, L.J. and Sauer, S.
Data in Brief 9
: 433-437.
December 2016
Hormetic shifting of redox environment by pro-oxidative resveratrol protects cells against stress.
Plauth, A., Geikowski, A., Cichon, S., Wowro, S.J., Liedgens, L., Rousseau, M., Weidner, C., Fuhr, L., Kliem, M., Jenkins, G., Lotito, S., Wainwright, L.J. and Sauer, S.
Free Radical Biology and Medicine 99
: 608-622.
October 2016
Impact of anti-PEG IgM antibodies on the pharmacokinetics of pegylated asparaginase preparations in mice.
Poppenborg, S.M., Wittmann, J., Walther, W., Brandenburg, G., Kraehmer, R., Baumgart, J. and Leenders, F.
European Journal of Pharmaceutical Sciences 91
: 122-130.
25 August 2016
Direct chromosome-length haplotyping by single-cell sequencing.
Porubský, D., Sanders, A.D., van Wietmarschen, N., Falconer, E., Hills, M., Spierings, D.C.J., Bevova, M.R., Guryev, V. and Lansdorp, P.M.
Genome Research 26
(11): 1565-1574.
November 2016
MicroRNAs: an adaptive mechanism in the pancreatic β-cell…and beyond?
Poy, M.N.
Best Practice & Research Clinical Endocrinology & Metabolism 30
(5): 621-628.
October 2016
Comparisons of chromosome Y-substituted mouse strains reveal that the male-specific chromosome modulates the effects of androgens on cardiac functions.
Praktiknjo, S.D., Picard, S. and Deschepper, C.F.
Biology of Sex Differences 7
: 61.
23 November 2016
High spatial resolution cardiovascular magnetic resonance at 7.0 Tesla in patients with hypertrophic cardiomyopathy - first experiences: lesson learned from 7.0 Tesla.
Prothmann, M., von Knobelsdorff-Brenkenhoff, F., Töpper, A., Dieringer, M.A., Shahid, E., Graessl, A., Rieger, J., Lysiak, D., Thalhammer, C., Huelnhagen, T., Kellman, P., Niendorf, T. and Schulz-Menger, J.
PLoS ONE 11
(2): e0148066.
10 February 2016
CD74-downregulation of placental macrophage-trophoblastic interactions in preeclampsia.
Przybyl, L., Haase, N., Golic, M., Rugor, J., Solano, M.E., Arck, P.C., Gauster, M., Huppertz, B., Emontzpohl, C., Stoppe, C., Bernhagen, J., Leng, L., Bucala, R., Schulz, H., Heuser, A., Weedon-Fekjær, S., Johnsen, G.M., Peetz, D., Luft, F.C., Staff, A.C., Müller, D.N., Dechend, R. and Herse, F.
Circulation Research 119
(1): 55-68.
24 June 2016
Increased activity of the immunoregulatory enzyme indoleamine-2,3-dioxygenase (IDO) with consecutive tryptophan depletion predicts death in patients with neuroendocrine neoplasia.
Pschowski, R., Pape, U.F., Fusch, G., Fischer, C., Jann, H., Baur, A., Arsenic, R., Wiedenmann, B., von Haehling, S., Pavel, M. and Schefold, J.C.
Neuroendocrinology 104
(2): 135-144.
December 2016
Immune modulation and prevention of autoimmune disease by repeated sequences from parasites linked to self antigens.
Puentes, F., Dickhaut, K., Hofstätter, M., Pfeil, J., Lauer, U., Hamann, A., Hoffmann, U., Falk, K. and Roetzschke, O.
Journal of Neuroimmune Pharmacology 11
(4): 749-762.
December 2016
Acute hypothalamo-pituitary-adrenal axis response to LPS-induced endotoxemia: expression pattern of kinin type B1 and B2 receptors.
Qadri, F., Rimmele, F., Mallis, L., Häuser, W., Dendorfer, A., Jöhren, O., Dominiak, P., Leeb-Lundberg, L.M.F. and Bader, M.
Biological Chemistry 397
(2): 97-109.
January 2016
New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Qi, J., Yu, Y., Akilli Öztürk, Ö., Holland, J.D., Besser, D., Fritzmann, J., Wulf-Goldenberg, A., Eckert, K., Fichtner, I. and Birchmeier, W.
Gut 65
(10): 1690-1701.
October 2016
Knockout of the PKN family of Rho effector kinases reveals a non-redundant role for PKN2 in developmental mesoderm expansion.
Quétier, I., Marshall, J.J.T., Spencer-Dene, B., Lachmann, S., Casamassima, A., Franco, C., Escuin, S., Worrall, J.T., Baskaran, P., Rajeeve, V., Howell, M., Copp, A.J., Stamp, G., Rosewell, I., Cutillas, P., Gerhardt, H., Parker, P.J. and Cameron, A.J.M.
Cell Reports 14
(3): 440-448.
26 January 2016
Increased vascular sympathetic modulation in mice with Mas receptor deficiency.
Rabello Casali, K., Ravizzoni Dartora, D., Moura, M., Bertagnolli, M., Bader, M., Haibara, A., Alenina, N., Irigoyen, M.C. and Santos, R.A.
Journal of the Renin-Angiotensin-Aldosterone System 17
(2): 1470320316643643.
13 April 2016
Genetic deletion of ACE2 induces vascular dysfunction in C57BL/6 mice: role of nitric oxide imbalance and oxidative stress.
Rabelo, L.A., Todiras, M., Nunes-Souza, V., Qadri, F., Szijártó, I.A., Gollasch, M., Penninger, J.M., Bader, M., Santos, R.A. and Alenina, N.
PLoS ONE 11
(4): e0150255.
12 April 2016
Electrophysiological signature of homomeric and heteromeric glycine receptor channels.
Raltschev, C., Hetsch, F., Winkelmann, A., Meier, J.C. and Semtner, M.
Journal of Biological Chemistry 291
(34): 18030-18040.
19 August 2016
Analysis of lymphocytic DNA damage in early multiple sclerosis by automated γ-H2AX and 53BP1 foci detection: A case control study.
Rasche, L., Heiserich, L., Behrens, J.R., Lenz, K., Pfuhl, C., Wakonig, K., Gieß, R.M., Freitag, E., Eberle, C., Wuerfel, J., Doerr, J., Bauer, P., Bellmann-Strobl, J., Paul, F., Roggenbuck, D. and Ruprecht, K.
PLoS ONE 11
(1): e0147968.
28 January 2016
C/EBPβ regulates homeostatic and oncogenic gastric cell proliferation.
Regalo, G., Förster, S., Resende, C., Bauer, B., Fleige, B., Kemmner, W., Schlag, P.M., Meyer, T.F., Machado, J.C. and Leutz, A.
Journal of Molecular Medicine 94
(12): 1385-1395.
December 2016
Hypertensive retinopathy in a transgenic angiotensin-based model.
Reichhart, N., Haase, N., Crespo-Garcia, S., Skosyrski, S., Herrspiegel, C., Kociok, N., Fuchshofer, R., Dillinger, A., Poglitsch, M., Müller, D.N., Joussen, A.M., Luft, F.C., Dechend, R. and Strauß, O.
Clinical Science 130
(13): 1075-1088.
1 July 2016
The mutation p.E113K in the Schiff base counterion of rhodopsin is associated with two distinct retinal phenotypes within the same family.
Reiff, C., Owczarek-Lipska, M., Spital, G., Röger, C., Hinz, H., Jüschke, C., Thiele, H., Altmüller, J., Nürnberg, P., Da Costa, R. and Neidhardt, J.
Scientific Reports 6
: 36208.
4 November 2016
Normothermic mouse functional MRI of acute focal thermostimulation for probing nociception.
Reimann, H.M., Hentschel, J., Marek, J., Huelnhagen, T., Todiras, M., Kox, S., Waiczies, S., Hodge, R., Bader, M., Pohlmann, A. and Niendorf, T.
Scientific Reports 6
: 17230.
29 January 2016
Oxidative stress does not play a primary role in the toxicity induced with clinical doses of doxorubicin in myocardial H9c2 cells.
Rharass, T., Gbankoto, A., Canal, C., Kurşunluoğlu, G., Bijoux, A., Panáková, D. and Ribou, A.C.
Molecular and Cellular Biochemistry 413
(1): 199-215.
February 2016
In memoriam Prof. Dr. Hans-Juergen Eichhorn: Ehrenmitglied der DEGRO.
Richter, J. and Welker, K.
Strahlentherapie und Onkologie 192
(1): 63-64.
January 2016
In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors.
Richter, M., Saydaminova, K., Yumul, R., Krishnan, R., Liu, J., Nagy, E.E., Singh, M., Izsvák, Z., Cattaneo, R., Uckert, W., Palmer, D., Ng, P., Haworth, K.G., Kiem, H.P., Ehrhardt, A., Papayannopoulou, T. and Lieber, A.
Blood 128
(18): 2206-2217.
3 November 2016
Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD.
Riechers, S.P., Butland, S., Deng, Y., Skotte, N., Ehrnhoefer, D.E., Russ, J., Laine, J., Laroche, M., Pouladi, M.A., Wanker, E.E., Hayden, M.R. and Graham, R.K.
Human Molecular Genetics 25
(8): 1600-1618.
May 2016
TRPC6 G757D loss-of-function mutation associates with FSGS.
Riehle, M., Büscher, A.K., Gohlke, B.O., Kaßmann, M., Kolatsi-Joannou, M., Bräsen, J.H., Nagel, M., Becker, J.U., Winyard, P., Hoyer, P.F., Preissner, R., Krautwurst, D., Gollasch, M., Weber, S. and Harteneck, C.
Journal of the American Society of Nephrology 27
(9): 2771-2783.
September 2016
Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors.
Riemke, P., Czeh, M., Fischer, J., Walter, C., Ghani, S., Zepper, M., Agelopoulos, K., Lettermann, S., Gebhardt, M.L., Mah, N., Weilemann, A., Grau, M., Groening, V., Haferlach, T., Lenze, D., Delwel, R., Prinz, M., Andrade-Navarro, M.A., Lenz, G., Dugas, M., Mueller-Tidow, C. and Rosenbauer, F.
EMBO Journal 35
(22): 2399-2416.
15 November 2016
The application of DamID to identify peripheral gene sequences in differentiated and primary cells.
Robson, M.I. and Schirmer, E.C.
Methods in molecular biology (Clifton, N.J.) 1411
(1411): 359-86.
2016
Tissue-specific gene repositioning by muscle nuclear membrane proteins enhances repression of critical developmental genes during myogenesis.
Robson, M.I., de Las Heras, J.I., Czapiewski, R., Lê Thành, P., Booth, D.G., Kelly, D.A., Webb, S., Kerr, A.R.W. and Schirmer, E.C.
Molecular Cell 62
(6): 834-847.
16 June 2016
OpenMS: a flexible open-source software platform for mass spectrometry data analysis.
Roest, H.L., Sachsenberg, T., Aiche, S., Bielow, C., Weisser, H., Aicheler, F., Andreotti, S., Ehrlich, H.C., Gutenbrunner, P., Kenar, E., Liang, X., Nahnsen, S., Nilse, L., Pfeuffer, J., Rosenberger, G., Rurik, M., Schmitt, U., Veit, J., Walzer, M., Wojnar, D., Wolski, W.E., Schilling, O., Choudhary, J.S., Malmstroem, L., Aebersold, R., Reinert, K. and Kohlbacher, O.
Nature Methods 13
(9): 741-748.
September 2016
Y-box protein-1/p18 as novel serum marker for ovarian cancer diagnosis: a study by the Tumor Bank Ovarian Cancer (TOC).
Rohr, I., Braicu, E.I., En-Nia, A., Heinrich, M., Richter, R., Chekerov, R., Dechend, R., Heidecke, H., Dragun, D., Schäfer, R., Gorny, X., Lindquist, J., Brandt, S., Sehouli, J. and Mertens, P.R.
Cytokine 85
: 157-164.
September 2016
Safety and clinical outcomes of rituximab treatment in patients with multiple sclerosis and neuromyelitis optica: experience from a national online registry (GRAID).
Rommer, P.S., Dörner, T., Freivogel, K., Haas, J., Kieseier, B.C., Kümpfel, T., Paul, F., Proft, F., Schulze-Koops, H., Schmidt, E., Wiendl, H., Ziemann, U. and Zettl, U.K.
Journal of Neuroimmune Pharmacology 11
(1): 1-8.
March 2016
Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses.
Roux, S., Brum, J.R., Dutilh, B.E., Sunagawa, S., Duhaime, M.B., Loy, A., Poulos, B.T., Solonenko, N., Lara, E., Poulain, J., Pesant, S., Kandels-Lewis, S., Dimier, C., Picheral, M., Searson, S., Cruaud, C., Alberti, A., Duarte, C.M., Gasol, J.M., Vaque, D., Bork, P., Acinas, S.G., Wincker, P. and Sullivan, M.B.
Nature 537
(7622): 689-693.
29 September 2016
Ndufc2 gene inhibition is associated with mitochondrial dysfunction and increased stroke susceptibility in an animal model of complex human disease.
Rubattu, S., Di Castro, S., Schulz, H., Geurts, A.M., Cotugno, M., Bianchi, F., Maatz, H., Hummel, O., Falak, S., Stanzione, R., Marchitti, S., Scarpino, S., Giusti, B., Kura, A., Gensini, G.F., Peyvandi, F., Mannucci, P.M., Rasura, M., Sciarretta, S., Dwinell, M.R., Hubner, N. and Volpe, M.
Journal of the American Heart Association 5
(2): e00270.
17 February 2016
An analysis of the sensitivity of proteogenomic mapping of somatic mutations and novel splicing events in cancer.
Ruggles, K.V., Tang, Z., Wang, X., Grover, H., Askenazi, M., Teubl, J., Cao, S., McLellan, M.D., Clauser, K.R., Tabb, D.L., Mertins, P., Slebos, R., Erdmann-Gilmore, P., Li, S., Gunawardena, H.P., Xie, L., Liu, T., Zhou, J.Y., Sun, S., Hoadley, K.A., Perou, C.M., Chen, X., Davies, S.R., Maher, C.A., Kinsinger, C.R., Rodland, K.D., Zhang, H., Zhang, Z., Ding, L., Townsend, R.R., Rodriguez, H., Chan, D., Smith, R.D., Liebler, D.C., Carr, S.A., Payne, S., Ellis, M.J. and Fenyö, D.
Molecular & Cellular Proteomics 15
(3): 1060-1071.
1 March 2016
Association of TMTC2 with human nonsyndromic sensorineural hearing loss.
Runge, C.L., Indap, A., Zhou, Y., Kent, J.W., King, E., Erbe, C.B., Cole, R., Littrell, J., Merath, K., James, R., Rüschendorf, F., Kerschner, J.E., Marth, G., Hübner, N., Göring, H.H.H., Friedland, D.R., Kwok, W.M. and Olivier, M.
JAMA Otolaryngology Head & Neck Surgery 142
(9): 866-872.
1 September 2016
Molecular dissection of valproic acid effects in acute myeloid leukemia identifies predictive networks.
Rücker, F.G., Lang, K.M., Fütterer, M., Komarica, V., Schmid, M., Döhner, H., Schlenk, R.F., Döhner, K., Knudsen, S. and Bullinger, L.
Epigenetics 11
(7): 517-525.
2 July 2016
RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics.
Salzer, E., Cagdas, D., Hons, M., Mace, E.M., Garncarz, W., Petronczki, Ö.Y., Platzer, R., Pfajfer, L., Bilic, I., Ban, S.A., Willmann, K.L., Mukherjee, M., Supper, V., Hsu, H.T., Banerjee, P.P., Sinha, P., McClanahan, F., Zlabinger, G.J., Pickl, W.F., Gribben, J.G., Stockinger, H., Bennett, K.L., Huppa, J.B., Dupré, L., Sanal, Ö., Jäger, U., Sixt, M., Tezcan, I., Orange, J.S. and Boztug, K.
Nature Immunology 17
(12): 1352-1360.
December 2016
Loss of MeCP2 disrupts cell autonomous and autocrine BDNF signaling in mouse glutamatergic neurons.
Sampathkumar, C., Wu, Y.J., Vadhvani, M., Trimbuch, T., Eickholt, B. and Rosenmund, C.
eLife 5
: e19374.
26 October 2016
Characterizing polymorphic inversions in human genomes by single-cell sequencing.
Sanders, A.D., Hills, M., Porubský, D., Guryev, V., Falconer, E. and Lansdorp, P.M.
Genome Research 26
(11): 1575-1587.
November 2016
A meta-analysis of the impact of pre-existing and new-onset atrial fibrillation on clinical outcomes in patients undergoing transcatheter aortic valve implantation.
Sannino, A., Gargiulo, G., Schiattarella, G.G., Perrino, C., Stabile, E., Losi, M.A., Galderisi, M., Izzo, R., de Simone, G., Trimarco, B. and Esposito, G.
EuroIntervention 12
(8): e1047-e1056.
10 October 2016
Metabolic profiling as well as stable isotope assisted metabolic and proteomic analysis of RAW 264.7 macrophages exposed to ship engine aerosol emissions: different effects of heavy fuel Oil and refined diesel fuel.
Sapcariu, S.C., Kanashova, T., Dilger, M., Diabate, S., Oeder, S., Passig, J., Radischat, C., Buters, J., Sippula, O., Streibel, T., Paur, H.R., Schlager, C., Muelhopt, S., Stengel, B., Rabe, R., Harndorf, H., Krebs, T., Karg, E., Groeger, T., Weiss, C., Dittmar, G., Hiller, K. and Zimmermann, R.
PLoS ONE 11
(6): e0157964.
27 June 2016
Rewinding the process of mammalian extinction.
Saragusty, J., Diecke, S., Drukker, M., Durrant, B., Friedrich Ben-Nun, I., Galli, C., Goeritz, F., Hayashi, K., Hermes, R., Holtze, S., Johnson, S., Lazzari, G., Loi, P., Loring, J.F., Okita, K., Renfree, M.B., Seet, S., Voracek, T., Stejskal, J., Ryder, O.A. and Hildebrandt, T.B.
Zoo Biology 35
(4): 280-292.
July 2016
Benchmarking the next generation of homology inference tools.
Saripella, G.V., Sonnhammer, E.L.L. and Forslund, K.
Bioinformatics 32
(17): 2636-2641.
1 September 2016
DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis.
Sarnowski, C., Laprise, C., Malerba, G., Moffatt, M.F., Dizier, M.H., Morin, A., Vincent, Q.B., Rohde, K., Esparza-Gordillo, J., Margaritte-Jeannin, P., Liang, L., Lee, Y.A., Bousquet, J., Siroux, V., Pignatti, P.F., Cookson, W.O., Lathrop, M., Pastinen, T., Demenais, F. and Bouzigon, E.
Journal of Allergy and Clinical Immunology 138
(3): 748-753.
September 2016
Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia.
Schaefer, M., Oeing, C.U., Rohm, M., Baysal-Temel, E., Lehmann, L.H., Bauer, R., Volz, H.C., Boutros, M., Sohn, D., Sticht, C., Gretz, N., Eichelbaum, K., Werner, T., Hirt, M.N., Eschenhagen, T., Mueller-Decker, K., Strobel, O., Hackert, T., Krijgsveld, J., Katus, H.A., Berriel Diaz, M., Backs, J. and Herzig, S.
Molecular Metabolism 5
(2): 67-78.
February 2016
The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.
Scharaw, S., Iskar, M., Ori, A., Boncompain, G., Laketa, V., Poser, I., Lundberg, E., Perez, F., Beck, M., Bork, P. and Pepperkok, R.
Journal of Cell Biology 215
(4): 543-558.
21 November 2016
Akap1 deficiency promotes mitochondrial aberrations and exacerbates cardiac injury following permanent coronary ligation via enhanced mitophagy and apoptosis.
Schiattarella, G.G., Cattaneo, F., Pironti, G., Magliulo, F., Carotenuto, G., Pirozzi, M., Polishchuk, R., Borzacchiello, D., Paolillo, R., Oliveti, M., Boccella, N., Avvedimento, M., Sepe, M., Lombardi, A., Busiello, R.A., Trimarco, B., Esposito, G., Feliciello, A. and Perrino, C.
PLoS ONE 11
(5): e0154076.
2 May 2016
Therapeutic targeting of autophagy in cardiovascular disease.
Schiattarella, G.G. and Hill, J.A.
Journal of Molecular and Cellular Cardiology 95
: 86-93.
June 2016
Chemical cross-linking stabilizes native-like HIV-1 envelope glycoprotein trimer antigens.
Schiffner, T., de Val, N., Russell, R.A., de Taeye, S.W., de la Peña, A.T., Ozorowski, G., Kim, H.J., Nieusma, T., Brod, F., Cupo, A., Sanders, R.W., Moore, J.P., Ward, A.B. and Sattentau, Q.J.
Journal of Virology 90
(2): 813-828.
15 January 2016
Joint analysis of multiple phenotypes: summary of results and discussions from the Genetic Analysis Workshop 19.
Schillert, A. and Konigorski, S.
BMC Genetics 17
(Suppl 2): 7.
3 February 2016
Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity.
Schirmer, D., Grünewald, T.G.P., Klar, R., Schmidt, O., Wohlleber, D., Rubio, R.A., Uckert, W., Thiel, U., Bohne, F., Busch, D.H., Krackhardt, A.M., Burdach, S. and Richter, G.H.S.
OncoImmunology 5
(6): e1175795.
25 April 2016
Fine specificity of the antibody response to Epstein-Barr nuclear antigen-2 and other Epstein-Barr virus proteins in patients with clinically isolated syndrome: a peptide microarray-based case-control study.
Schlemm, L., Giess, R.M., Rasche, L., Pfuhl, C., Wakonig, K., Behrens, J.R., Scheibenbogen, C., Bellmann-Strobl, J., Paul, F., Reimer, U. and Ruprecht, K.
Journal of Neuroimmunology 297
: 56-62.
15 August 2016
Quantitative, organ-specific interscanner and intrascanner variability for 3 T whole-body magnetic resonance imaging in a multicenter, multivendor study.
Schlett, C.L., Hendel, T., Hirsch, J., Weckbach, S., Caspers, S., Schulz-Menger, J., Ittermann, T., von Knobelsdorff-Brenkenhoff, F., Ladd, S.C., Moebus, S., Stroszczynski, C., Fischer, B., Leitzmann, M., Kuhl, C., Pessler, F., Hartung, D., Kemmling, Y., Hetterich, H., Amunts, K., Guenther, M., Wacker, F., Rummeny, E., Kauczor, H.U., Forsting, M., Völzke, H., Hosten, N., Reiser, M.F. and Bamberg, F.
Investigative Radiology 51
(4): 255-265.
April 2016
The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment.
Schloss, M.J., Horckmans, M., Nitz, K., Duchene, J., Drechsler, M., Bidzhekov, K., Scheiermann, C., Weber, C., Soehnlein, O. and Steffens, S.
EMBO Molecular Medicine 8
(8): 937-948.
1 August 2016
Cardiac involvement in myotonic dystrophy type 2 patients with preserved ejection fraction: Detection by cardiovascular magnetic resonance.
Schmacht, L., Traber, J., Grieben, U., Utz, W., Dieringer, M.A., Kellman, P., Blaszczyk, E., von Knobelsdorff-Brenkenhoff, F., Spuler, S. and Schulz-Menger, J.
Circulation Cardiovascular Imaging 9
(7): e004615.
July 2016
SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival.
Schmid, F., Wang, Q., Huska, M.R., Andrade-Navarro, M.A., Lemm, M., Fichtner, I., Dahlmann, M., Kobelt, D., Walther, W., Smith, J., Schlag, P.M. and Stein, U.
Oncogene 35
(46): 5942-5952.
17 November 2016
GiANT: gene set uncertainty in enrichment analysis.
Schmid, F., Schmid, M., Müssel, C., Sträng, J.E., Buske, C., Bullinger, L., Kraus, J.M. and Kestler, H.A.
Bioinformatics 32
(12): 1891-1894.
15 June 2016
Dorsal root ganglion axon bifurcation tolerates increased cyclic GMP levels: the role of phosphodiesterase 2A and scavenger receptor Npr3.
Schmidt, H., Peters, S., Frank, K., Wen, L., Feil, R. and Rathjen, F.G.
European Journal of Neuroscience 44
(12): 2991-3000.
December 2016
SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity.
Schmidt, V., Schulz, N., Yan, X., Schürmann, A., Kempa, S., Kern, M., Blüher, M., Poy, M.N., Olivecrona, G. and Willnow, T.E.
Journal of Clinical Investigation 126
(7): 2706-2720.
1 July 2016
An automated workflow for parallel processing of large multiview SPIM recordings.
Schmied, C., Steinbach, P., Pietzsch, T., Preibisch, S. and Tomancak, P.
Bioinformatics 32
(7): 1112-1114.
1 April 2016
Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes.
Schmitt, J., Schwarz, K., Baurecht, H., Hotze, M., Fölster-Holst, R., Rodríguez, E., Lee, Y.A.E., Franke, A., Degenhardt, F., Lieb, W., Gieger, C., Kabesch, M., Nöthen, M.M., Irvine, A.D., McLean, W.H.I., Deckert, S., Stephan, V., Schwarz, P., Aringer, M., Novak, N. and Weidinger, S.
Journal of Allergy and Clinical Immunology 137
(1): 130-136.
January 2016
Accuracy and repeatability of two methods of gait analysis - GaitRite(TM) und Mobility Lab(TM) - in subjects with cerebellar ataxia.
Schmitz-Hübsch, T., Brandt, A.U., Pfueller, C., Zange, L., Seidel, A., Kühn, A.A., Paul, F., Minnerop, M. and Doss, S.
Gait & Posture 48
: 194-201.
July 2016
A lipidomic analysis approach in patients undergoing lipoprotein apheresis.
Schmoecker, C., Kassner, U., Kiesler, S., Bismarck, M., Rothe, M., Steinhagen-Thiessen, E. and Weylandt, K.H.
Atherosclerosis 249
: 30-35.
June 2016
Transcriptome analysis of murine olfactory sensory neurons during development using single cell RNA-Seq.
Scholz, P., Kalbe, B., Jansen, F., Altmüller, J., Becker, C., Mohrhardt, J., Schreiner, B., Gisselmann, G., Hatt, H. and Osterloh, S.
Chemical Senses 41
(4): 313-323.
May 2016
A movement disorder with dystonia and ataxia caused by a mutation in the HIBCH gene.
Schottmann, G., Sarpong, A., Lorenz, C., Weinhold, N., Gill, E., Teschner, L., Ferdinandusse, S., Wanders, R.J.A., Prigione, A. and Schuelke, M.
Movement Disorders 31
(11): 1733-1739.
November 2016
Lessons from a double-transgenic neutrophil approach to induce antiproteinase 3 antibody-mediated vasculitis in mice.
Schreiber, A., Eulenberg-Gustavus, C., Bergmann, A., Jerke, U. and Kettritz, R.
Journal of Leukocyte Biology 100
(6): 1443-1452.
December 2016
Reduction of apoptosis and preservation of mitochondrial integrity under ischemia/reperfusion injury is mediated by estrogen receptor β.
Schubert, C., Raparelli, V., Westphal, C., Dworatzek, E., Petrov, G., Kararigas, G. and Regitz-Zagrosek, V.
Biology of Sex Differences 7
: 53.
23 September 2016
Lysosomal dysfunction caused by cellular accumulation of silica nanoparticles.
Schuetz, I., Lopez-Hernandez, T., Gao, Q., Puchkov, D., Jabs, S., Nordmeyer, D., Schmudde, M., Ruehl, E., Graf, C.M. and Haucke, V.
Journal of Biological Chemistry 291
(27): 14170-14184.
1 July 2016
The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion.
Schulte, K., Pawlowski, N., Faelber, K., Fröhlich, C., Howard, J. and Daumke, O.
BMC Biology 14
(1): 14.
2 March 2016
The role of fludrocortisone in cognition and mood in patients with primary adrenal insufficiency (Addison's disease).
Schultebraucks, K., Wingenfeld, K., Otte, C. and Quinkler, M.
Neuroendocrinology 103
(3-4): 315-320.
May 2016
Neuromyelitis optica does not impact periventricular venous density versus healthy controls: a 7.0 Tesla MRI clinical study.
Schumacher, S., Pache, F., Bellmann-Strobl, J., Behrens, J., Dusek, P., Harms, L., Ruprecht, K., Nytrova, P., Chawla, S., Niendorf, T., Kister, I., Paul, F., Ge, Y., Wuerfel, J. and Sinnecker, T.
Magnetic Resonance Materials in Physics Biology and Medicine 29
(3): 535-541.
June 2016
Cardiomyocyte-specific overexpression of estrogen receptor beta improves survival and cardiac function after myocardial infarction in female and male mice.
Schuster, I., Mahmoodzadeh, S., Dworatzek, E., Jaisser, F., Messaoudi, S., Morano, I. and Regitz-Zagrosek, V.
Clinical Science 130
(5): 365-376.
26 January 2016
PML risk stratification using anti-JCV antibody index and L-selectin.
Schwab, N., Schneider-Hohendorf, T., Pignolet, B., Spadaro, M., Görlich, D., Meinl, I., Windhagen, S., Tackenberg, B., Breuer, J., Cantó, E., Kümpfel, T., Hohlfeld, R., Siffrin, V., Luessi, F., Posevitz-Fejfár, A., Montalban, X., Meuth, S.G., Zipp, F., Gold, R., Du Pasquier, R.A., Kleinschnitz, C., Jacobi, A., Comabella, M., Bertolotto, A., Brassat, D. and Wiendl, H.
Multiple Sclerosis Journal 22
(8): 1048-1060.
July 2016
ALVIS: interactive non-aggregative visualization and explorative analysis of multiple sequence alignments.
Schwarz, R.F., Tamuri, A.U., Kultys, M., King, J., Godwin, J., Florescu, A.M., Schultz, J. and Goldman, N.
Nucleic Acids Research 44
(8): e77.
5 May 2016
Association between alcohol consumption and serum paraoxonase and arylesterase activities: a cross-sectional study within the Bavarian population.
Schwedhelm, C., Nimptsch, K., Bub, A., Pischon, T. and Linseisen, J.
British Journal of Nutrition 115
(4): 730-736.
February 2016
KCNQ potassium channels modulate sensitivity of skin D-hair mechanoreceptors.
Schütze, S., Orozco, I.J. and Jentsch, T.J.
Journal of Biological Chemistry 291
(11): 5566-5575.
11 March 2016
Myc depletion induces a pluripotent dormant state mimicking diapause.
Scognamiglio, R., Cabezas-Wallscheid, N., Thier, M.C., Altamura, S., Reyes, A., Prendergast, Á.M., Baumgärtner, D., Carnevalli, L.S., Atzberger, Ann, Haas, S., von Paleske, L., Boroviak, T., Wörsdörfer, P., Essers, M.A.G., Kloz, U., Eisenman, R.N., Edenhofer, F., Bertone, P., Huber, W., van der Hoeven, F., Smith, A. and Trumpp, A.
Cell 164
(4): 668-680.
11 February 2016
Increasing Notch signaling antagonizes PRC2-mediated silencing to promote reprograming of germ cells into neurons.
Seelk, S., Adrian-Kalchhauser, I., Hargitai, B., Hajduskova, M., Gutnik, S., Tursun, B. and Ciosk, R.
eLife 5
: e15477.
7 September 2016
The Slavic NBN founder mutation: a role for reproductive fitness?
Seemanova, E., Varon, R., Vejvalka, J., Jarolim, P., Seeman, P., Chrzanowska, K.H., Digweed, M., Resnick, I., Kremensky, I., Saar, K., Hoffmann, K., Dutrannoy, V., Karbasiyan, M., Ghani, M., Baric, I., Tekin, M., Kovacs, P., Krawczak, M., Reis, A., Sperling, K. and Nothnagel, M.
PLoS ONE 11
(12): e0167984.
9 December 2016
The progressive ankyloses protein ANK facilitates clathrin- and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosome interface.
Seifert, W., Posor, Y., Schu, P., Stenbeck, G., Mundlos, S., Klaassen, S., Nürnberg, P., Haucke, V., Kornak, U. and Kühnisch, J.
Human Molecular Genetics 25
(17): 3836-3848.
1 September 2016
Vasodilator effect of glucagon: receptorial crosstalk among glucagon, GLP-1, and receptor for glucagon and GLP-1.
Selley, E., Kun, S., Szijártó, I.A., Kertesz, M., Wittmann, I. and Molnar, G.A.
Hormone and Metabolic Research 48
(7): 476-483.
July 2016
Drug-induced myocarditis after nivolumab treatment in a patient with PDL1- negative squamous cell carcinoma of the lung.
Semper, H., Muehlberg, F., Schulz-Menger, J., Allewelt, M. and Grohe, C.
Lung Cancer 99
: 117-119.
September 2016
Polycomb repressive complex 2 is a barrier to KRAS-driven inflammation and epithelial-mesenchymal transition in non-small-cell lung cancer.
Serresi, M., Gargiulo, G., Proost, N., Siteur, B., Cesaroni, M., Koppens, M., Xie, H., Sutherland, K.D., Hulsman, D., Citterio, E., Orkin, S., Berns, A. and van Lohuizen, M.
Cancer Cell 29
(1): 17-31.
11 January 2016
Combined fluorescence and phosphorescence lifetime imaging.
Shcheslavskiy, V.I., Neubauer, A., Bukowiecki, R., Dinter, F. and Becker, W.
Applied Physics Letters 108
(9): 091111.
3 March 2016
ECM signaling regulates collective cellular dynamics to control pancreas branching morphogenesis.
Shih, H.P., Panlasigui, D., Cirulli, V. and Sander, M.
Cell Reports 14
(2): 169-79.
12 January 2016
TAK1 adaptor proteins TAB2 and TAB3 link the signalosome to B cell receptor-induced IKK activation.
Shinohara, H., Yasuda, T. and Kurosaki, T.
FEBS Letters 590
(18): 3264-3269.
September 2016
Structure of AP205 coat protein reveals circular permutation in ssRNA bacteriophages.
Shishovs, M., Rumnieks, J., Diebolder, C., Jaudzems, K., Andreas, L.B., Stanek, J., Kazaks, A., Kotelovica, S., Akopjana, I., Pintacuda, G., Koning, R.I. and Tars, K.
Journal of Molecular Biology 428
(21): 4267-4279.
23 October 2016
The "Big-Bang" for modern glial biology: translation and comments on Pio del Rio-Hortega 1919 series of papers on microglia.
Sierra, A., de Castro, F., Del Rio-Hortega, J., Iglesias-Rozas, J.R., Garrosa, M. and Kettenmann, H.
Glia 64
(11): 1801-1840.
November 2016
Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing.
Sifrim, A., Hitz, M.P., Wilsdon, A., Breckpot, J., Turki, S.H.A., Thienpont, B., McRae, J., Fitzgerald, T.W., Singh, T., Swaminathan, G.J., Prigmore, E., Rajan, D., Abdul-Khaliq, H., Banka, S., Bauer, U.M.M., Bentham, J., Berger, F., Bhattacharya, S., Bu'Lock, F., Canham, N., Colgiu, I.G., Cosgrove, C., Cox, H., Daehnert, I., Daly, A., Danesh, J., Fryer, A., Gewillig, M., Hobson, E., Hoff, K., Homfray, T., Kahlert, A.K., Ketley, A., Kramer, H.H., Lachlan, K., Lampe, A.K., Louw, J.J., Manickara, A.K., Manase, D., McCarthy, K.P., Metcalfe, K., Moore, C., Newbury-Ecob, R., Omer, S.O., Ouwehand, W.H., Park, S.M., Parker, M.J., Pickardt, T., Pollard, M.O., Robert, L., Roberts, D.J., Sambrook, J., Setchfield, K., Stiller, B., Thornborough, C., Toka, O., Watkins, H., Williams, D., Wright, M., Mital, S., Daubeney, P.E.F., Keavney, B., Goodship, J., Abu-Sulaiman, R.M., Klaassen, S., Wright, C.F., Firth, H.V., Barrett, J.C., Devriendt, K., FitzPatrick, D.R., Brook, J.D. and Hurles, M.E.
Nature Genetics 48
(9): 1060-1065.
1 August 2016
The role of kinin B1 receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents.
Silva, C.R., Oliveira, S.M., Hoffmeister, C., Funck, V., Guerra, G.P., Trevisan, G., Tonello, R., Rossato, M.F., Pesquero, J.B., Bader, M., Oliveira, M.S., McDougall, J.J. and Ferreira, J.
Annals of the Rheumatic Diseases 75
(1): 260-268.
January 2016
OCT4 acts as an integrator of pluripotency and signal-induced differentiation.
Simandi, Z., Horvath, A., Wright, L.C., Cuaranta-Monroy, I., De Luca, I., Karolyi, K., Sauer, S., Deleuze, J.F., Gudas, L.J., Cowley, S.M. and Nagy, L.
Molecular Cell 63
(4): 647-661.
18 August 2016
Non-canonical autophagy LAPs lupus.
Simon, A.K. and Clarke, A.J.
Cell Death and Differentiation 23
(8): 1267-8.
August 2016
Urinary NGAL-positive acute kidney injury and poor long-term Ootcomes in hospitalized patients.
Singer, E., Schrezenmeier, E.V., Elger, A., Seelow, E.R., Krannich, A., Luft, F.C. and Schmidt-Ott, K.M.
Kidney International Reports 1
(3): 114-124.
September 2016
Second-line treatment in pancreatic cancer patients: Who profits? Results from the CONKO study group.
Sinn, M., Daelken, L., Striefler, J.K., Bischoff, S., Schweitzer, N., Pelzer, U., Doerken, B., Riess, H. and Stieler, J.M.
Pancreas 45
(4): 601-605.
April 2016
Progressive multifocal leukoencephalopathy in a multiple Sclerosis patient diagnosed after switching from natalizumab to fingolimod.
Sinnecker, T., Othman, J., Kühl, M., Metz, I., Niendorf, T., Kunkel, A., Paul, F., Wuerfel, J. and Faiss, Juergen
Case Reports in Neurological Medicine 2016
: 5876798.
22 November 2016
MRI phase changes in multiple sclerosis vs neuromyelitis optica lesions at 7T.
Sinnecker, T., Schumacher, S., Mueller, K., Pache, F., Dusek, P., Harms, L., Ruprecht, K., Nytrova, P., Chawla, S., Niendorf, T., Kister, I., Paul, F., Ge, Y. and Wuerfel, J.
Neurology Neuroimmunology & Neuroinflammation 3
(4): e259.
August 2016
WITHDRAWN-a resource for withdrawn and discontinued drugs.
Siramshetty, V.B., Nickel, J., Omieczynski, C., Gohlke, B.O., Drwal, M.N. and Preissner, R.
Nucleic Acids Research 44
(D1): D1080-D1086.
4 January 2016
Regulation of G0/G1 switch gene 2 (G0S2) expression in human adipose tissue.
Skopp, A., May, M., Janke, J., Kielstein, H., Wunder, R., Flade-Kuthe, R., Kuthe, A., Jordan, J. and Engeli, S.
Archives of Physiology and Biochemistry 122
(2): 47-53.
14 March 2016
Conserved functional antagonism of CELF 1 and MBNL proteins controls stem cell-specific alternative splicing in planarians.
Solana, J., Irimia, M., Ayoub, S., Orejuela, M.R., Zywitza, V., Jens, M., Tapial, J., Ray, D., Morris, Q.D., Hughes, T.R., Blencowe, B.J. and Rajewsky, N.
eLife 5
: e16797.
9 August 2016
Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells.
Soucie, E.L., Weng, Z., Geirsdóttir, L., Molawi, K., Maurizio, J., Fenouil, R., Mossadegh-Keller, N., Gimenez, G., VanHille, L., Beniazza, M., Favret, J., Berruyer, C., Perrin, P., Hacohen, N., Andrau, J.C., Ferrier, P., Dubreuil, P., Sidow, A. and Sieweke, M.H.
Science 351
(6274): aad5510.
12 February 2016
Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice.
Spielmann, M., Kakar, N., Tayebi, N., Leettola, C., Nürnberg, G., Sowada, N., Lupiáñez, D.G., Harabula, I., Flöttmann, R., Horn, D., Chan, W.L., Wittler, L., Yilmaz, R., Altmüller, J., Thiele, H., van Bokhoven, H., Schwartz, C.E., Nürnberg, P., Bowie, J.U., Ahmad, J., Kubisch, C., Mundlos, S. and Borck, G.
Genome Research 26
(2): 183-191.
February 2016
Exome sequencing identifies potential novel candidate genes in patients with unexplained colorectal adenomatous polyposis.
Spier, I., Kerick, M., Drichel, D., Horpaopan, S., Altmüller, J., Laner, A., Holzapfel, S., Peters, S., Adam, R., Zhao, B., Becker, T., Lifton, R.P., Holinski-Feder, E., Perner, S., Thiele, H., Nöthen, M.M., Hoffmann, P., Timmermann, B., Schweiger, M.R. and Aretz, S.
Familial Cancer 15
(2): 281-288.
April 2016
Inhibition of chymotryptic-like standard proteasome activity exacerbates doxorubicin-induced cytotoxicity in primary cardiomyocytes.
Spur, E.M., Althof, N., Respondek, D., Klingel, K., Heuser, A., Overkleeft, H.S. and Voigt, A.
Toxicology 353-354
: 34-47.
15 April 2016
Automated detection and quantification of single RNAs at cellular resolution in zebrafish embryos.
Stapel, L.C., Lombardot, B., Broaddus, C., Kainmueller, D., Jug, F., Myers, E.W. and Vastenhouw, N.L.
Development 143
(3): 540-546.
1 February 2016
The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6.
Stauss, D., Brunner, C., Berberich-Siebelt, F., Höpken, U.E., Lipp, M. and Müller, G.
EMBO Journal 35
(8): 881-898.
15 April 2016
Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.
Stellos, K., Gatsiou, A., Stamatelopoulos, K., Perisic Matic, L., John, D., Lunella, F.F., Jae, N., Rossbach, O., Amrhein, C., Sigala, F., Boon, R.A., Fuertig, B., Manavski, Y., You, X., Uchida, S., Keller, T., Boeckel, J.N., Franco-Cereceda, A., Maegdefessel, L., Chen, W., Schwalbe, H., Bindereif, A., Eriksson, P., Hedin, U., Zeiher, A.M. and Dimmeler, S.
Nature Medicine 22
(10): 1140-1150.
October 2016
Cannabinoid type 2 receptors mediate a cell type-specific plasticity in the hippocampus.
Stempel, A.V., Stumpf, A., Zhang, H.Y., Özdoğan, T., Pannasch, U., Theis, A.K., Otte, D.M., Wojtalla, A., Racz, I., Ponomarenko, A., Xi, Z.X., Zimmer, A. and Schmitz, D.
Neuron 90
(4): 795-809.
18 May 2016
DNA methylation in an engineered heart tissue model of cardiac hypertrophy: common signatures and effects of DNA methylation inhibitors.
Stenzig, J., Hirt, M.N., Löser, A., Bartholdt, L.M., Hensel, J.T., Werner, T.R., Riemenschneider, M., Indenbirken, D., Guenther, T., Müller, C., Hübner, N., Stoll, M. and Eschenhagen, T.
Basic Research in Cardiology 111
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January 2016
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery.
Stunnenberg, H.G. and Hirst, M.
Cell 167
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17 November 2016
A comprehensive RNA sequencing analysis of the adeno-associated virus (AAV) type 2 transcriptome reveals novel AAV transcripts, splice variants, and derived proteins.
Stutika, C., Gogol-Doering, A., Botschen, L., Mietzsch, M., Weger, S., Feldkamp, M., Chen, W. and Heilbronn, R.
Journal of Virology 90
(3): 1278-1289.
February 2016
Comprehensive small RNA-Seq of adeno-associated virus (AAV)-infected human cells detects patterns of novel, non-coding AAV RNAs in the absence of cellular miRNA regulation.
Stutika, C., Mietzsch, M., Gogol-Doering, A., Weger, S., Sohn, M., Chen, W. and Heilbronn, R.
PLoS ONE 11
(9): e0161454.
9 September 2016
Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients.
Szasz, A.M., Lanczky, A., Nagy, A., Foerster, S., Hark, K., Green, J.E., Boussioutas, A., Busuttil, R., Szabo, A. and Gyorffy, B.
Oncotarget 7
(31): 49322-49333.
2 August 2016
A novel homozygous splicing mutation of CASC5 causes primary microcephaly in a large Pakistani family.
Szczepanski, S., Hussain, M.S., Sur, I., Altmüller, J., Thiele, H., Abdullah, U., Waseem, S.S., Moawia, A., Nürnberg, G., Noegel, A.A., Baig, S.M. and Nürnberg, P.
Human Genetics 135
(2): 157-170.
February 2016
STITCH 5: augmenting protein-chemical interaction networks with tissue and affinity data.
Szklarczyk, D., Santos, A., von Mering, C., Jensen, L.J., Bork, P. and Kuhn, M.
Nucleic Acids Research 44
(D1): D380-D384.
4 January 2016
Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples.
Szulzewsky, F., Arora, S., de Witte, L., Ulas, T., Markovic, D., Schultze, J.L., Holland, E.C., Synowitz, M., Wolf, S.A. and Kettenmann, H.
Glia 64
(8): 1416-1436.
August 2016
Omega-3 and alpha-tocopherol provide more protection against contaminants in novel feeds for Atlantic salmon (Salmo salar L.) than omega-6 and gamma tocopherol.
Søfteland, L., Berntssen, M.H.G., Kirwan, J.A., Størseth, T.R., Viant, M.R., Torstensen, B.E., Waagbø, R. and Olsvik, P.A.
Toxicology Reports 3
: 211-224.
14 January 2016
Reproducibility of differential proteomic technologies in CPTAC fractionated xenografts.
Tabb, D.L., Wang, X., Carr, S.A., Clauser, K.R., Mertins, P., Chambers, M.C., Holman, J.D., Wang, J., Zhang, B., Zimmerman, L.J., Chen, X., Gunawardena, H.P., Davies, S.R., Ellis, M.J.C., Li, S., Townsend, R.R., Boja, E.S., Ketchum, K.A., Kinsinger, C.R., Mesri, M., Rodriguez, H., Liu, T., Kim, S., McDermott, J.E., Payne, S.H., Petyuk, V.A., Rodland, K.D., Smith, R.D., Yang, F., Chan, D.W., Zhang, B., Zhang, H., Zhang, Z., Zhou, J.Y. and Liebler, D.C.
Journal of Proteome Research 15
(3): 691-706.
4 March 2016
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.
Tan, J., Pieper, K., Piccoli, L., Abdi, A., Foglierini, M., Geiger, R., Tully, C.M., Jarrossay, D., Ndungu, F.M., Wambua, J., Bejon, P., Silacci Fregni, C., Fernandez-Rodriguez, B., Barbieri, S., Bianchi, S., Marsh, K., Thathy, V., Corti, D., Sallusto, F., Bull, P. and Lanzavecchia, A.
Nature 529
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7 January 2016
Functional architecture of the rat parasubiculum.
Tang, Q., Burgalossi, A., Ebbesen, C.L., Sanguinetti-Scheck, J.I., Schmidt, H., Tukker, J.J., Naumann, R., Ray, S., Preston-Ferrer, P., Schmitz, D. and Brecht, M.
Journal of Neuroscience 36
(7): 2289-2301.
17 February 2016
Superpriming of synaptic vesicles as a common basis for intersynapse variability and modulation of synaptic strength.
Taschenberger, H., Woehler, A. and Neher, E.
Proceedings of the National Academy of Sciences of the United States of America 113
(31): E4548-E4557.
2 August 2016
Predicting chronic copper and nickel reproductive toxicity to Daphnia pulex-pulicaria from whole-animal metabolic profiles.
Taylor, N.S., Kirwan, J.A., Johnson, C., Yan, N.D., Viant, M.R., Gunn, J.M. and McGeer, J.C.
Environmental Pollution 212
: 325-329.
May 2016
Metabolomics confirms that dissolved organic carbon mitigates copper toxicity.
Taylor, N.S., Kirwan, J.A., Yan, N.D., Viant, M.R., Gunn, J.M. and McGeer, J.C.
Environmental Toxicology and Chemistry 35
(3): 635-644.
March 2016
Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements.
Telorac, J., Prykhozhij, S.V., Schöne, S., Meierhofer, D., Sauer, S., Thomas-Chollier, M. and Meijsing, S.H.
Nucleic Acids Research 44
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27 July 2016
Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.
Textor, A., Schmidt, K., Kloetzel, P.M., Weißbrich, B., Perez, C., Charo, J., Anders, K., Sidney, J., Sette, A., Schumacher, T.N.M., Keller, C., Busch, D.H., Seifert, U. and Blankenstein, T.
Journal of Experimental Medicine 213
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17 October 2016
The German Hypertension League (Deutsche Hochdruckliga) Quality Seal Protocol for blood pressure-measuring devices: 15-year experience and results from 105 devices for home blood pressure control.
Tholl, U., Lüders, S., Bramlage, P., Dechend, R., Eckert, S., Mengden, T., Nürnberger, J., Sanner, B. and Anlauf, M.
Blood Pressure Monitoring 21
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August 2016
RNF4-dependent oncogene activation by protein stabilization.
Thomas, J.J., Abed, M., Heuberger, J., Novak, R., Zohar, Y., Beltra-Lopez, A.P., Trausch-Azar, J.S., Ilagan, M.X.G., Benhamou, D., Dittmar, G., Kopan, R., Birchmeier, W., Schwartz, A.L. and Orian, A.
Cell Reports 16
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20 September 2016
Identification of novel and recurrent disease-causing mutations in retinal dystrophies using whole exome sequencing (WES): Benefits and limitations.
Tiwari, A., Lemke, J., Altmüller, J., Thiele, H., Glaus, E., Fleischhauer, J., Nürnberg, P., Neidhardt, J. and Berger, W.
PLoS ONE 11
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8 July 2016
The WOPR protein Ros1 is a master regulator of sporogenesis and late effector gene expression in the maize pathogen Ustilago maydis.
Tollot, M., Assmann, D., Becker, C., Altmüller, J., Dutheil, J.Y., Wegner, C.E. and Kahmann, R.
PLoS Pathogens 12
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June 2016
LHX2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.
Tomann, P., Paus, R., Millar, S.E., Scheidereit, C. and Schmidt-Ullrich, R.
Development 143
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1 May 2016
Real-time phase contrast magnetic resonance imaging for assessment of haemodynamics: from phantom to patients.
Traber, J., Wurche, L., Dieringer, M.A., Utz, W., von Knobelsdorff-Brenkenhoff, F., Greiser, A., Jin, N. and Schulz-Menger, J.
European Radiology 26
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April 2016
Blood flow characteristics in the ascending aorta after TAVI compared to surgical aortic valve replacement.
Trauzeddel, R.F., Löbe, U., Barker, A.J., Gelsinger, C., Butter, C., Markl, M., Schulz-Menger, J. and von Knobelsdorff-Brenkenhoff, F.
International Journal of Cardiovascular Imaging 32
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March 2016
Cellular localization and adaptive changes of the cardiac delta opioid receptor system in an experimental model of heart failure in rats.
Treskatsch, S., Feldheiser, A., Shaqura, M., Dehe, L., Habazettl, H., Roepke, T.K., Shakibaei, M., Schaefer, M., Spies, C.D. and Mousa, S.A.
Heart and Vessels 31
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February 2016
Evidence for MOR on cell membrane, sarcoplasmatic reticulum and mitochondria in left ventricular myocardium in rats.
Treskatsch, S., Shaqura, M., Dehe, L., Roepke, T.K., Shakibaei, M., Schaefer, M. and Mousa, S.A.
Heart and Vessels 31
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August 2016
A CD2AP mutation associated with focal segmental glomerulosclerosis in young adulthood.
Tsvetkov, D., Hohmann, M., Anistan, Y.M., Mannaa, M., Harteneck, C., Rudolph, B. and Gollasch, M.
Clinical Medicine Insights: Case Reports 9
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14 March 2016
Better understanding of phosphoinositide 3-Kinase (PI3K) pathways in vasculature: towards precision therapy targeting angiogenesis and tumor blood supply.
Tsvetkov, D., Shymanets, A., Huang, Y., Bucher, K., Piekorz, R., Hirsch, E., Beer-Hammer, S., Harteneck, C., Gollasch, M. and Nürnberg, B.
Biochemistry 81
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July 2016
The role of DPO-1 and XE991-sensitive potassium channels in perivascular adipose tissue-mediated regulation of vascular tone.
Tsvetkov, D., Tano, J.Y., Kassmann, M., Wang, N., Schubert, R. and Gollasch, M.
Frontiers in Physiology 7
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4 August 2016
Sleeping Beauty transposon vectors in liver directed gene delivery of LDLR and VLDLR for gene therapy of familial hypercholesterolemia.
Turunen, T.A.K., Kurkipuro, J., Heikura, T., Vuorio, T., Hytönen, E., Izsvák, Z. and Ylä-Herttuala, S.
Molecular Therapy 24
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March 2016
Impact of surgical correction of pectus excavatum on cardiac function: insights on the right ventricle. A cardiovascular magnetic resonance study.
Töpper, A., Polleichtner, S., Zagrosek, A., Prothmann, M., Traber, J., Schwenke, C., von Knobelsdorff-Brenkenhoff, F., Schaarschmidt, K. and Schulz-Menger, J.
Interactive Cardiovascular and Thoracic Surgery 22
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January 2016
Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion.
Ubezio, B., Blanco, R.A., Geudens, I., Stanchi, F., Mathivet, T., Jones, M.L., Ragab, A., Bentley, K. and Gerhardt, H.
eLife 5
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13 April 2016
Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4.
Uckelmann, H., Blaszkiewicz, S., Nicolae, C., Haas, S., Schnell, A., Wurzer, S., Wagener, R., Aszodi, A. and Essers, M.A.G.
Journal of Experimental Medicine 213
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19 September 2016
Actin dynamics shape microglia effector functions.
Uhlemann, R., Gertz, K., Boehmerle, W., Schwarz, T., Nolte, C., Freyer, D., Kettenmann, H., Endres, M. and Kronenberg, G.
Brain Structure & Function 221
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June 2016
Inactivation and anion selectivity of volume-regulated VRAC channels depend on carboxy-terminal residues of the first extracellular loop.
Ullrich, F., Reincke, S.M., Voss, F.K., Stauber, T. and Jentsch, T.J.
Journal of Biological Chemistry 291
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12 August 2016
Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3.
Van Haute, L., Dietmann, S., Kremer, L., Hussain, S., Pearce, S.F., Powell, C.A., Rorbach, J., Lantaff, R., Blanco, S., Sauer, S., Kotzaeridou, U., Hoffmann, G.F., Memari, Y., Kolb-Kokocinski, A., Durbin, R., Mayr, J.A., Frye, M., Prokisch, H. and Minczuk, M.
Nature Communications 7
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30 June 2016
Development of siRNA-loaded chitosan nanoparticles targeting Galectin-1 for the treatment of glioblastoma multiforme via intranasal administration.
Van Woensel, M., Wauthoz, N., Rosière, R., Mathieu, V., Kiss, R., Lefranc, F., Steelant, B., Dilissen, E., Van Gool, S.W., Mathivet, T., Gerhardt, H., Amighi, K. and De Vleeschouwer, S.
Journal of Controlled Release 227
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10 April 2016
Poor sleep in multiple sclerosis correlates with Beck Depression Inventory values, but not with polysomnographic data.
Veauthier, C., Gaede, G., Radbruch, H., Wernecke, K.D. and Paul, F.
Sleep Disorders 2016
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2016
Identification of a novel agonist-like autoantibody in preeclamptic patients.
Velloso, E.P., Pimentel, R.L., Braga, J.F., Cabral, A.C.V., Reis, Z.S.N., Bader, M., Santos, R.A.S. and Wallukat, G.
American Journal of Hypertension 29
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March 2016
Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain.
Ventéo, S., Laffray, S., Wetzel, C., Rivat, C., Scamps, F., Méchaly, I., Bauchet, L., Raoul, C., Bourinet, E., Lewin, G.R., Carroll, P. and Pattyn, A.
Scientific Reports 6
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2 November 2016
Resolving lipid mediators maresin 1 and resolvin D2 prevent atheroprogression in mice.
Viola, J.R., Lemnitzer, P., Jansen, Y., Csaba, G., Winter, C., Neideck, C., Silvestre-Roig, C., Dittmar, G., Doering, Y., Drechsler, M., Weber, C., Zimmer, R., Cenac, N. and Soehnlein, O.
Circulation Research 119
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14 October 2016
The traveling heads: multicenter brain imaging at 7 Tesla.
Voelker, M.N., Kraff, O., Brenner, D., Wollrab, A., Weinberger, O., Berger, M.C., Robinson, S., Bogner, W., Wiggins, C., Trampel, R., Stoecker, T., Niendorf, T., Quick, H.H., Norris, D.G., Ladd, M.E. and Speck, O.
Magnetic Resonance Materials in Physics Biology and Medicine 29
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June 2016
Colorectal cancer and the human gut microbiome: reproducibility with whole-genome shotgun sequencing.
Vogtmann, E., Hua, X., Zeller, G., Sunagawa, S., Voigt, A.Y., Hercog, R., Goedert, J.J., Shi, J., Bork, P. and Sinha, R.
PLoS ONE 11
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12 May 2016
Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering.
Voigt, F., Wiedemann, L., Zuliani, C., Querques, I., Sebe, A., Mátés, L., Izsvák, Z., Ivics, Z. and Barabas, O.
Nature Communications 7
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30 March 2016
Analysis of genes involved in body weight regulation by targeted re-sequencing.
Volckmar, A.L., Han, C.T., Pütter, C., Haas, S., Vogel, C.I.G., Knoll, N., Struve, C., Göbel, M., Haas, K., Herrfurth, N., Jarick, I., Grallert, H., Schürmann, A., Al-Hasani, H., Hebebrand, J., Sauer, S. and Hinney, A.
PLoS ONE 11
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1 February 2016
Neuropathological signs of inflammation correlate with mitochondrial DNA deletions in mesial temporal lobe epilepsy.
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Acta Neuropathologica 132
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August 2016
Altered paired associative stimulation-induced plasticity in NMDAR encephalitis.
Volz, M.S., Finke, C., Harms, L., Jurek, B., Paul, F., Flöel, A. and Prüss, H.
Annals of Clinical and Translational Neurology 3
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February 2016
The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation.
Vučićević, D., Gehre, M., Dhamija, S., Friis-Hansen, L., Meierhofer, D., Sauer, S. and Ørom, U.A.
Oncotarget 7
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7 June 2016
A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large.
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BMC Biology 14
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9 August 2016
Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders.
Wakabayashi, A., Ulirsch, J.C., Ludwig, L.S., Fiorini, C., Yasuda, M., Choudhuri, A., McDonel, P., Zon, L.I. and Sankaran, V.G.
Proceedings of the National Academy of Sciences of the United States of America 113
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19 April 2016
Exposure to zidovudine adversely affects mitochondrial turnover in primary T cells.
Wallace, Z.R., Sanderson, S., Simon, A.K. and Dorrell, L.
Antiviral Research 133
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September 2016
TTC25 deficiency results in defects of the outer dynein arm docking machinery and primary ciliary dyskinesia with left-right body asymmetry randomization.
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American Journal of Human Genetics 99
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4 August 2016
Epigenetic dynamics of monocyte-to-macrophage differentiation.
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29 July 2016
Configurable NOR gate arrays from Belousov-Zhabotinsky micro-droplets.
Wang, A.L., Gold, J.M., Tompkins, N., Heymann, M., Harrington, K.I. and Fraden, S.
European Physical Journal Special Topics 225
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February 2016
Isolation and cultivation of naive-like human pluripotent stem cells based on HERVH expression.
Wang, J., Singh, M., Sun, C., Besser, D., Prigione, A., Ivics, Z., Hurst, L.D. and Izsvák, Z.
Nature Protocols 11
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February 2016
Wars2 is a determinant of angiogenesis.
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Nature Communications 7
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8 July 2016
Pervasive isoform-specific translational regulation via alternative transcription start sites in mammals.
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Molecular Systems Biology 12
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18 July 2016
Maternal forced swimming reduces cell proliferation in the postnatal dentate gyrus of mouse offspring.
Wasinski, F., Estrela, G.R., Arakaki, A.M., Bader, M., Alenina, N., Klempin, F. and Araújo, R.C.
Frontiers in Neuroscience 10
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29 August 2016
Multicentre comparison of a diagnostic assay: aquaporin-4 antibodies in neuromyelitis optica.
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Journal of Neurology Neurosurgery and Psychiatry 87
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September 2016
Sequential poly-ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase.
Weber, A., Cohen, I., Popp, O., Dittmar, G., Reiss, Y., Sommer, T., Ravid, T. and Jarosch, E.
Molecular Cell 63
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1 September 2016
Expression and functionality of TRPV1 in breast cancer cells.
Weber, L.V., Al-Refae, K., Wölk, G., Bonatz, G., Altmüller, J., Becker, C., Gisselmann, G. and Hatt, H.
Breast Cancer: Targets and Therapy 8
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13 December 2016
Caspase-mediated apoptosis induction in zebrafish cerebellar Purkinje neurons.
Weber, T., Namikawa, K., Winter, B., Müller-Brown, K., Kühn, R., Wurst, W. and Köster, R.W.
Development 143
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15 November 2016
Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation.
Wedmann, R., Onderka, C., Wei, S., Szijártó, I.A., Miljkovic, J.L., Mitrovic, A., Lange, M., Savitsky, S., Yadav, P.K., Torregrossa, R., Harrer, E.G., Harrer, T., Ishii, I., Gollasch, M., Wood, M.E., Galardon, E., Xian, M., Whiteman, M., Banerjee, R. and Filipovic, M.R.
Chemical Science 7
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25 May 2016
Genome editing in mice using TALE nucleases.
Wefers, B., Brandl, C., Ortiz, O., Wurst, W. and Kühn, R.
Methods in Molecular Biology 1338
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2016
Amorfrutin C induces apoptosis and inhibits proliferation in colon cancer cells through targeting mitochondria.
Weidner, C., Rousseau, M., Micikas, R.J., Fischer, C., Plauth, A., Wowro, S.J., Siems, K., Hetterling, G., Kliem, M., Schroeder, F.C. and Sauer, S.
Journal of Natural Products 79
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22 January 2016
Iberis amara extract induces intracellular formation of reactive oxygen species and inhibits colon cancer.
Weidner, C., Rousseau, M., Plauth, A., Wowro, S.J., Fischer, C., Abdel-Aziz, H. and Sauer, S.
PLoS ONE 11
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6 April 2016
Local multi-channel RF surface coil versus body RF coil transmission for cardiac magnetic resonance at 3 Tesla: which configuration is winning the game?
Weinberger, O., Winter, L., Dieringer, M.A., Els, A., Oezerdem, C., Rieger, J., Kuehne, A., Cassara, A.M., Pfeiffer, H., Wetterling, F. and Niendorf, T.
PLoS ONE 11
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6 September 2016
Experimental cortical spreading depression induces NMDA receptor dependent potassium currents in microglia.
Wendt, S., Wogram, E., Korvers, L. and Kettenmann, H.
Journal of Neuroscience 36
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8 June 2016
Identifying RBP targets with RIP-seq.
Wessels, H.H., Hirsekorn, A., Ohler, U. and Mukherjee, N.
Methods in Molecular Biology 1358
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2016
The mRNA-bound proteome of the early fly embryo.
Wessels, H.H., Imami, K., Baltz, A.G., Kolinski, M., Beldovskaya, A., Selbach, M., Small, S., Ohler, U. and Landthaler, M.
Genome Research 26
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July 2016
Comprehensive translational control of tyrosine kinase expression by upstream open reading frames.
Wethmar, K., Schulz, J., Muro, E.M., Talyan, S., Andrade-Navarro, M.A. and Leutz, A.
Oncogene 35
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31 March 2016
Stress-induced brain activity, brain atrophy, and clinical disability in multiple sclerosis.
Weygandt, M., Meyer-Arndt, L., Behrens, J.R., Wakonig, K., Bellmann-Strobl, J., Ritter, K., Scheel, M., Brandt, A.U., Labadie, C., Hetzer, S., Gold, S.M., Paul, F. and Haynes, J.D.
Proceedings of the National Academy of Sciences of the United States of America 113
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22 November 2016
Docosapentaenoic acid derived metabolites and mediators-the new world of lipid mediator medicine in a nutshell.
Weylandt, K.H.
European Journal of Pharmacology 785
: 108-115.
15 August 2016
Dysregulated development of IL-17-and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORγt.
Wichner, K., Stauss, D., Kampfrath, B., Krüger, K., Müller, G., Rehm, A., Lipp, M. and Höpken, U.E.
FASEB Journal 30
(2): 761-774.
February 2016
Dietary omega-3 polyunsaturated fatty acids prevent vascular dysfunction and attenuate cytochrome P4501A1 expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Wiest, E.F., Walsh-Wilcox, M.T., Rothe, M., Schunck, W.H. and Walker, M.K.
Toxicological Sciences 154
(1): 43-54.
November 2016
FOXO1 couples metabolic activity and growth state in the vascular endothelium.
Wilhelm, K., Happel, K., Eelen, G., Schoors, S., Oellerich, M.F., Lim, R., Zimmermann, B., Aspalter, I.M., Franco, C.A., Boettger, T., Braun, T., Fruttiger, M., Rajewsky, K., Keller, C., Brüning, J.C., Gerhardt, H., Carmeliet, P. and Potente, M.
Nature 529
(7585): 216-220.
14 January 2016
Metabolische Regulation des Blutgefäßwachstums [Metabolic regulation of blood vessel growth].
Wilhelm, K. and Potente, M.
BIOspektrum 22
(6): 597-599.
2 October 2016
The brain renin-angiotensin system plays a crucial role in regulating body weight in diet-induced rat obesity.
Winkler, M., Schuchard, J., Stölting, I., Vogt, F.M., Barkhausen, J., Thorns, C., Bader, M. and Raasch, W.
British Journal of Pharmacology 173
(10): 1602-1617.
May 2016
Developing antagonists for the Met-HGF/SF protein-protein interaction using a fragment-based approach.
Winter, A., Sigurdardottir, A.G., DiCara, D., Valenti, G., Blundell, T.L. and Gherardi, E.
Molecular Cancer Therapeutics 15
(1): 3-14.
January 2016
Electrodynamics and radiofrequency antenna concepts for human magnetic resonance at 23.5 T (1 GHz) and beyond.
Winter, L. and Niendorf, T.
Magnetic Resonance Materials in Physics Biology and Medicine 29
(3): 641-656.
June 2016
Mouse model for acute Epstein-Barr virus infection.
Wirtz, T., Weber, T., Kracker, S., Sommermann, T., Rajewsky, K. and Yasuda, T.
Proceedings of the National Academy of Sciences of the United States of America 113
(48): 13821-13826.
29 November 2016
Satellite microglia display spontaneous electrical activity uncorrelated with activity of the attached neuron.
Wogram, E., Wendt, S., Matyash, M., Pivneva, T., Draguhn, A. and Kettenmann, H.
European Journal of Neuroscience 43
(11): 1523-1534.
June 2016
Spatially resolved genome-wide transcriptional profiling identifies BMP signaling as essential regulator of zebrafish cardiomyocyte regeneration.
Wu, C.C., Kruse, F., Vasudevarao, M.D., Junker, J.P., Zebrowski, D.C., Fischer, K., Noel, E.S., Gruen, D., Berezikov, E., Engel, F.B., van Oudenaarden, A., Weidinger, G. and Bakkers, J.
Developmental Cell 36
(1): 36-49.
11 January 2016
Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation.
Xiao, M.S., Zhang, B., Li, Y.S., Gao, Q., Sun, W. and Chen, W.
Molecular Systems Biology 12
(12): 890.
8 December 2016
Core-multishell nanocarriers: transport and release of dexamethasone probed by soft x-ray spectromicroscopy.
Yamamoto, K., Klossek, A., Flesch, R., Ohigashi, T., Fleige, E., Rancan, F., Frombach, J., Vogt, A., Blume-Peytavi, U., Schrade, P., Bachmann, S., Haag, R., Hedtrich, S., Schäfer-Korting, M., Kosugi, N. and Rühl, E.
Journal of Controlled Release 242
: 64-70.
28 November 2016
A syndrome of microcephaly, short stature, polysyndactyly, and dental anomalies caused by a homozygous KATNB1 mutation.
Yigit, G., Wieczorek, D., Bögershausen, N., Beleggia, F., Möller-Hartmann, C., Altmüller, J., Thiele, H., Nürnberg, P. and Wollnik, B.
American Journal of Medical Genetics Part A 170
(3): 728-733.
March 2016
Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants.
Yung, H.W., Alaes-Katjavivi, P., Jones, C.J.P., El-Bacha, T., Golic, M., Staff, A.C. and Burton, G.J.
Diabetologia 59
(10): 2240-2250.
October 2016
2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines: The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC).
Zamorano, J.L., Lancellotti, P., Rodriguez Munoz, D., Aboyans, V., Asteggiano, R., Galderisi, M., Habib, G., Lenihan, D.J., Lip, G.Y.H., Lyon, A.R., Lopez Fernandez, T., Mohty, D., Piepoli, M.F., Tamargo, J., Torbicki, A. and Suter, T.M.
European Heart Journal 37
(36): 2768-2801.
21 September 2016
Cell-specific synaptic plasticity induced by network oscillations.
Zarnadze, S., Bäuerle, P., Santos-Torres, J., Böhm, C., Schmitz, D., Geiger, J.R.P., Dugladze, T. and Gloveli, T.
eLife 5
: e14912.
24 May 2016
Quantitative analysis of cancer metabolism: From pSIRM to MFA.
Zasada, C. and Kempa, S.
Recent Results in Cancer Research 207
(207): 207-220.
25 August 2016
PCNA appears in two populations of slow and fast diffusion with a constant ratio throughout S-phase in replicating mammalian cells.
Zessin, P.J.M., Sporbert, A. and Heilemann, M.
Scientific Reports 6
: 18779.
13 January 2016
Two-year outcomes of patients treated with aliskiren under clinical practice conditions: non-interventional prospective study.
Zeymer, U., Dechend, R., Riemer, T., Deeg, E., Senges, J., Pittrow, D. and Schmieder, R.
Journal of Clinical Hypertension 18
(7): 647-654.
July 2016
Integrated proteogenomic characterization of human high-grade serous ovarian cancer.
Zhang, H., Liu, T., Zhang, Z., Payne, S.H., Zhang, B., McDermott, J.E., Zhou, J.Y., Petyuk, V.A., Chen, L., Ray, D., Sun, S., Yang, F., Chen, L., Wang, J., Shah, P., Cha, S.W., Aiyetan, P., Woo, S., Tian, Y., Gritsenko, M.A., Clauss, T.R., Choi, C., Monroe, M.E., Thomas, S., Nie, S., Wu, C., Moore, R.J., Yu, K.H., Tabb, D.L., Fenyö, D., Bafna, V., Wang, Y., Rodriguez, H., Boja, E.S., Hiltke, T., Rivers, R.C., Sokoll, L., Zhu, H., Shih, I.M., Cope, L., Pandey, A., Zhang, B., Snyder, M.P., Levine, D.A., Smith, R.D., Chan, D.W. and Rodland, K.D.
Cell 166
(3): 755-765.
28 July 2016
Translaminar cortical membrane potential synchrony in behaving mice.
Zhao, W.J., Kremkow, J. and Poulet, J.F.A.
Cell Reports 15
(11): 2387-2399.
14 June 2016
Renal ischemia/reperfusion injury in soluble epoxide hydrolase-deficient mice.
Zhu, Y., Blum, M., Hoff, U., Wesser, T., Fechner, M., Westphal, C., Gürgen, D., Catar, R.A., Philippe, A., Wu, K., Bubalo, G., Rothe, M., Weldon, S.M., Dragun, D. and Schunck, W.H.
PLoS ONE 11
(1): e0145645.
4 January 2016
FHL1B Interacts with lamin A/C and emerin at the nuclear lamina and is misregulated in Emery-Dreifuss Muscular Dystrophy.
Ziat, E., Mamchaoui, K., Beuvin, M., Nelson, I., Azibani, F., Spuler, S., Bonne, G. and Bertrand, A.T.
Journal of Neuromuscular Diseases 3
(4): 497-510.
29 November 2016
High-resolution in situ hybridization analysis on the chromosomal interval 61C7-61C8 of Drosophila melanogaster reveals interbands as open chromatin domains.
Zielke, T., Glotov, A. and Saumweber, H.
Chromosoma 125
(3): 423-435.
June 2016
Functional characterisation of human synaptic genes expressed in the Drosophila brain.
Zografos, L., Tang, J., Hesse, F., Wanker, E.E., Li, K.W., Smit, A.B., Davies, R.W. and Armstrong, J.D.
Biology Open 5
(5): 662-667.
15 May 2016
Glioma stem cells but not bulk glioma cells upregulate IL-6 secretion in microglia/brain macrophages via toll-like receptor 4 signaling.
a Dzaye, O.D., Hu, F., Derkow, K., Haage, V., Euskirchen, P., Harms, C., Lehnardt, S., Synowitz, M., Wolf, S.A. and Kettenmann, H.
Journal of Neuropathology and Experimental Neurology 75
(5): 429-440.
1 May 2016
Kinin receptors in skin wound healing.
da Soley, B., Morais, R.L.T., Pesquero, J.B., Bader, M., Otuki, M.F. and Cabrini, D.A.
Journal of Dermatological Science 82
(2): 95-105.
May 2016
A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P., Kaergel, E., Heinig, M., Fontaine, J.F., Patone, G., Muro, E.M., Mathas, S., Hummel, M., Andrade-Navarro, M.A., Hübner, N. and Scheidereit, C.
Genome Medicine 8
(1): 28.
17 March 2016
52 genetic loci influencing myocardial mass.
van der Harst, P., van Setten, J., Verweij, N., Vogler, G., Franke, L., Maurano, M.T., Wang, X., Mateo Leach, I., Eijgelsheim, M., Sotoodehnia, N., Hayward, C., Sorice, R., Meirelles, O., Lyytikaeinen, L.P., Polašek, O., Tanaka, T., Arking, D.E., Ulivi, S., Trompet, S., Mueller-Nurasyid, M., Smith, A.V., Dörr, M., Kerr, K.F., Magnani, J.W., Del Greco, M.F., Zhang, W., Nolte, I.M., Silva, C.T., Padmanabhan, S., Tragante, V., Esko, T., Abecasis, G.R., Adriaens, M.E., Andersen, K., Barnett, P., Bis, J.C., Bodmer, R., Buckley, B.M., Campbell, H., Cannon, M.V., Chakravarti, A., Chen, L.Y., Delitala, A., Devereux, R.B., Doevendans, P.A., Dominiczak, A.F., Ferrucci, L., Ford, I., Gieger, C., Harris, T.B., Haugen, E., Heinig, M., Hernandez, D.G., Hillege, H.L., Hirschhorn, J.N., Hofman, A., Hubner, N., Hwang, S.J., Iorio, A., Kaehoenen, M., Kellis, M., Kolcic, I., Kooner, Is.K., Kooner, J.S., Kors, J.A., Lakatta, E.G., Lage, K., Launer, L.J., Levy, D., Lundby, A., Macfarlane, P.W., May, D., Meitinger, T., Metspalu, A., Nappo, S., Naitza, S., Neph, S., Nord, A.S., Nutile, T., Okin, P.M., Olsen, J.V., Oostra, B.A., Penninger, J.M., Pennacchio, L.A., Pers, T.H., Perz, S., Peters, A., Pinto, Y.M., Pfeufer, A., Pilia, M.G., Pramstaller, P.P., Prins, B.P., Raitakari, O.T., Raychaudhuri, S., Rice, K.M., Rossin, E.J., Rotter, J.I., Schaefer, S., Schlessinger, D., Schmidt, C.O., Sehmi, J., Sillje, H.H.W., Sinagra, G., Sinner, M.F., Slowikowski, K., Soliman, E.Z., Spector, T.D., Spiering, W., Stamatoyannopoulos, J.A., Stolk, R.P., Strauch, K., Tan, S.T., Tarasov, K.V., Trinh, B., Uitterlinden, A.G., van den Boogaard, M., van Duijn, C.M., van Gilst, W.H., Viikari, J.S., Visscher, P.M., Vitart, V., Völker, U., Waldenberger, M., Weichenberger, C.X., Westra, H.J., Wijmenga, C., Wolffenbuttel, B.H., Yang, J., Bezzina, C.R., Munroe, P.B., Snieder, H., Wright, A.F., Rudan, I., Boyer, L.A., Asselbergs, F.W., van Veldhuisen, D.J., Stricker, B.H., Psaty, B.M., Ciullo, M., Sanna, S., Lehtimäki, T., Wilson, J.F., Bandinelli, S., Alonso, A., Gasparini, P., Jukema, J.W., Kääb, S., Gudnason, V., Felix, S.B., Heckbert, S.R., de Boer, R.A., Newton-Cheh, C., Hicks, A.A., Chambers, J.C., Jamshidi, Y., Visel, A., Christoffels, V.M., Isaacs, A., Samani, N.J. and de Bakker, P.I.W.
Journal of the American College of Cardiology 68
(13): 1435-1448.
27 September 2016
The CUE domain of Cue1 aligns growing ubiquitin chains with Ubc7 for rapid elongation.
von Delbrück, M., Kniss, A., Rogov, V.V., Pluska, L., Bagola, K., Löhr, F., Güntert, P., Sommer, T. and Dötsch, V.
Molecular Cell 62
(6): 918-928.
16 June 2016
Myocardial dysfunction in patients with aortic stenosis and hypertensive heart disease assessed by MR tissue phase mapping.
von Knobelsdorff-Brenkenhoff, F., Hennig, P., Menza, M., Dieringer, M.A., Foell, D., Jung, B. and Schulz-Menger, J.
Journal of Magnetic Resonance Imaging 44
(1): 168-177.
July 2016
Evaluation of aortic blood flow and wall shear stress in aortic stenosis and its association with left ventricular remodeling.
von Knobelsdorff-Brenkenhoff, F., Karunaharamoorthy, A., Trauzeddel, R.F., Barker, A.J., Blaszczyk, E., Markl, M. and Schulz-Menger, J.
Circulation Cardiovascular Imaging 9
(3): e004038.
March 2016
Current T(1) and T(2) mapping techniques applied with simple thresholds cannot discriminate acute from chronic myocadial infarction on an individual patient basis: a pilot study.
von Knobelsdorff-Brenkenhoff, F., Prothmann, M., Dieringer, M.A., Wassmuth, R., Rudolph, A., Utz, W., Traber, J., Greiser, A., Niendorf, T. and Schulz-Menger, J.
BMC Medical Imaging 16
(1): 35.
29 April 2016
Role of cardiovascular magnetic resonance in the guidelines of the European Society of Cardiology.
von Knobelsdorff-Brenkenhoff, F. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 18
(1): 6.
22 January 2016
Cardiac fibrosis in aortic stenosis and hypertensive heart disease assessed by magnetic resonance T1 mapping.
von Knobelsdorff-Brenkenhoff, F., Mueller, A.K., Prothmann, M., Hennig, P., Dieringer, M.A., Schmacht, L., Greiser, A. and Schulz-Menger, J.
Journal of Heart Valve Disease 25
(5): 527-533.
September 2016
Book Section
Personal recollections about N.W. Timoféeff-Ressovsky and his action for radiation biophysics in Berlin-Buch and Dubna.
Abel, H. and Erzgräber, G.
In:
Genetics, Evolution and Radiation.
Springer, Cham, 33-37.
ISBN 978-3-319-48837-0
2016
Radiation risks and confusions.
Abel, H. and Erzgräber, G.
In:
Genetics, Evolution and Radiation.
Springer, Cham, 187-191.
ISBN 978-3-319-48837-0
2016
Human genetics of ventricular septal defect.
Bellmann, K., Perrot, A. and Rickert-Sperling, S.
In:
Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways.
Springer, Vienna, 307-328.
ISBN 978-3-7091-1882-5
2016
Technologies to study genetics and molecular pathways.
Dorn, C., Grunert, M., Dopazo, A., Sanchez-Cabo, F., Gatto, A., Vazquez, J., Rickert-Sperling, S. and Lara-Pezzi, E.
In:
Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways.
Springer, Vienna, 251-269.
ISBN 978-3-7091-1882-5
2016
Human genetics of tetralogy of fallot and double outlet right ventricle.
Dorn, C., Perrot, A. and Rickert-Sperling, S.
In:
Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways.
Springer, Vienna, 403-416.
ISBN 978-3-7091-1882-5
2016
Basic modelling principles: deterministic models.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In:
Models of calcium signalling.
Interdisciplinary Applied Mathematics, 43
.
Springer, Cham, Switzerland, 97-161.
ISBN 978-3-319-29645-6
2016
Hierarchical and stochastic modelling.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In:
Models of calcium signalling.
Interdisciplinary Applied Mathematics, 43
.
Springer, Cham, Switzerland, 163-205.
ISBN 978-3-319-29645-6
2016
Muscle.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In:
Models of Calcium Signalling.
Interdisciplinary Applied Mathematics, 43
.
Springer, Cham, Switzerland, 295-336.
ISBN 978-3-319-29645-6
2016
Neurons and other excitable cells.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In:
Models of Calcium Signalling.
Interdisciplinary Applied Mathematics, 43
.
Springer, Cham, Switzerland, 337-385.
ISBN 978-3-319-29645-6
2016
Nonexcitable cells.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In:
Models of Calcium Signalling.
Interdisciplinary Applied Mathematics, 43
.
Springer, Cham, Switzerland, 245-294.
ISBN 978-3-319-29645-6
2016
Nonlinear dynamics of calcium.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In:
Models of calcium signalling.
Interdisciplinary Applied Mathematics, 43
.
Springer, Cham, Switzerland, 207-242.
ISBN 978-3-319-29645-6
2016
Some background physiology.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In:
Models of calcium signalling.
Interdisciplinary Applied Mathematics, 43
.
Springer, Cham, Switzerland, 3-27.
ISBN 978-3-319-29645-6
2016
The calcium toolbox.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In:
Models of calcium signalling.
Interdisciplinary Applied Mathematics, 43
.
Springer, Cham, Switzerland, 29-96.
ISBN 978-3-319-29645-6
2016
Cardiac transcription factors and regulatory networks.
Grunert, M., Dorn, C. and Rickert-Sperling, S.
In:
Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways.
Springer, Vienna, 139-152.
ISBN 978-3-7091-1882-5
2016
Left ventricular noncompaction.
Hoedemaekers, Y.M. and Klaassen, S.
In:
Clinical Cardiogenetics.
Springer, Cham, 113-135.
ISBN 978-3-319-44202-0
2 December 2016
Single molecule methods to measure receptor–ligand interaction in immunological synapses.
Huppa, J.B. and Schütz, G.J.
In:
Encyclopedia of Cell Biology.
Reference Module in Biomedical Sciences, 3
.
Elsevier, 660-666.
ISBN 978-0-12-394796-3
2016
Convergent evolution within CEA gene families in mammals: hints for species-specific selection pressures.
Kammerer, R., Herse, F. and Zimmermann, W.
In:
Evolutionary Biology : Convergent Evolution, Evolution of Complex Traits, Concepts and Methods.
Springer International Publishing, Switzerland, 37-53.
ISBN 978-3-319-41323-5
2016
Glial cells: neuroglia.
Kettenmann, H. and Verkhratsky, A.
In:
Neuroscience in the 21st Century: From Basic to Clinical.
UNSPECIFIED, 547-578.
ISBN 978-1-4939-3473-7
27 October 2016
Essential myosin light chains regulate myosin function and muscle contraction.
Morano, I.
In:
Muscle Contraction and Cell Motility.
Pan Stanford Publishing, Singapore, 273-288.
ISBN 9789814745161
1 November 2016
The contractile apparatus of the heart.
Morano, I.
In:
Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways.
Springer, Vienna, 237-250.
ISBN 978-3-7091-1882-5
2016
Fluorinated natural compounds and synthetic drugs.
Niendorf, T., Ji, Y. and Waiczies, S.
In:
Fluorine Magnetic Resonance Imaging.
Pan Stanford Publishing, Singapore, 311-342.
ISBN 9781315364605
2016
Human genetics of defects of situs.
Perrot, A. and Rickert-Sperling, S.
In:
Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways.
Springer, Vienna, 463-472.
ISBN 978-3-7091-1882-5
2016
Nikolai V. Timoféeff-Ressovsky in Berlin-Buch (1925–1945).
Rajewsky, M., Lafuente, D. and Bader, M.
In:
Genetics, Evolution and Radiation.
Springer, 13-28.
ISBN 978-3-319-48837-0
2016
ANCA-associated vasculitis and the mechanisms of tissue injury.
Schreiber, A. and Choi, M.
In:
Systemic Vasculitides: Current Status and Perspectives.
Springer, Cham, 141-158.
ISBN 978-3-319-40134-8
14 October 2016
Pancreatic differentiation from human pluripotent stem cells.
Vinckier, N., Wang, J. and Sander, M.
In:
Working with stem cells.
Springer, Cham, 257-275.
ISBN 978-3-319-30580-6
5 August 2016
Tracking of dendritic cells.
Waiczies, S., Ku, M.C. and Niendorf, T.
In:
Fluorine Magnetic Resonance Imaging.
Pan Stanford Publishing, Singapore, 243-281.
ISBN 9781315364605
2016
Conference or Workshop Item
On fine stochastic simulations of liposome-encapsulated PUREsystem(TM).
Calviello, L., Lazzerini-Ospri, L. and Marangoni, R.
In: 10th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2015, 22-25 Sept 2015, Bari, Italy.
2016
Cseq-simulator: a data simulator for CLIP-Seq experiments.
Kassuhn, W., Ohler, U. and Drewe, P.
In: Pacific Symposium on Biocomputing (PSB) 2016, 4-8 Jan 2016, The Big Island of Hawaii, USA.
January 2016
Separating sparse signals from correlated noise in binary classification.
Mandt, S., Wenzel, F., Nakajima, S., Lippert, C. and Kloft, M.
In: 2016 UAI Workshop on Causation: Foundation to Application, UAI-CFA, 29 June 2016, Jersey City, United States.
2016
Mapping auto-context decision forests to deep ConvNets for semantic segmentation.
Richmond, D., Kainmueller, D., Yang, M., Myers, E. and Rother, C.
In: 27th British Machine Vision Conference, BMVC 2016, 19-22 Sep 2016, York, United Kingdom.
September 2016
Convexity shape constraints for image segmentation.
Royer, L.A., Richmond, D.L., Rother, C., Andres, B. and Kainmueller, D.
In: IEEE Conference on Computer Vision and Pattern Recognition, 27-30 Jun 2016, Las Vegas, USA.
2016
Book
Current strategies in cancer gene therapy.
Walther, W., ed.
Recent Results in Cancer Research, 209
.
Springer.
ISBN 978-3-319-42932-8
2016
Fluorine magnetic resonance imaging.
Flogel, U. and Ahrens, E., eds.
Jenny Stanford Publishing, New York, NY, USA.
ISBN 9781315364605
2016
Metabolism in cancer.
Cramer, T. and Schmitt, C., eds.
Recent Results in Cancer Research, 207
.
Springer.
ISBN 978-3-319-42118-6
2016
Models of calcium signalling.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
Interdisciplinary Applied Mathematics, 43
.
Springer, Cham, Switzerland.
ISBN 978-3-319-29645-6
2016
Genetics, evolution and radiation: Crossing borders, the interdisciplinary legacy of Nikolay W. Timofeeff-Ressovsky.
Korogodina, V.L., Mothersill, C.E., Inge-Vechtomov, S.G. and Seymour, C.B.
Springer, Cham, Switzerland.
ISBN 978-3-319-48837-0
2016
TALENs : Methods and Protocols.
Kuehn, R., Wurst, W. and Wefers, B.
Methods in Molecular Biology, 1338
.
Springer, New York.
ISBN 978-1-4939-2931-3
2016
Congenital heart diseases: the broken heart : clinical features, human genetics and molecular pathways.
Rickert-Sperling, S., Kelly, R.G. and Driscoll, D.J.
Springer, Vienna.
ISBN 978-3-7091-1882-5
2016
Patent
Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same.
Max-Delbrück-Centrum für Molekulare Medizin.
WO/2016/135199.
1 September 2016
Review
Risk factor SORL1: from genetic association to functional validation in Alzheimer's disease.
Andersen, O.M., Rudolph, I.M. and Willnow, T.E.
Acta Neuropathologica 132
(5): 653-665.
November 2016
Membrane fission by dynamin: what we know and what we need to know.
Antonny, B., Burd, C., De Camilli, P., Chen, E., Daumke, O., Faelber, K., Ford, M., Frolov, V.A., Frost, A., Hinshaw, J.E., Kirchhausen, T., Kozlov, M.M., Lenz, M., Low, H.H., McMahon, H., Merrifield, C., Pollard, T.D., Robinson, P.J., Roux, A. and Schmid, S.
EMBO Journal 35
(21): 2270-2284.
2 November 2016
Coelomic epithelium-derived cells in visceral morphogenesis.
Ariza, L., Carmona, R., Canete, A., Cano, E. and Munoz-Chapuli, R.
Developmental Dynamics 245
(3): 307-322.
March 2016
Proteomic techniques to probe the ubiquitin landscape.
Beaudette, P., Popp, O. and Dittmar, G.
Proteomics 16
(2): 273-287.
January 2016
The immunoproteasomes are key to regulate myokines and MHC class I expression in idiopathic inflammatory myopathies.
Bhattarai, S., Ghannam, K., Krause, S., Benveniste, O., Marg, A., de Bruin, G., Xin, B.T., Overkleeft, H.S., Spuler, S., Stenzel, W. and Feist, E.
Journal of Autoimmunity 75
: 118-129.
December 2016
Neuregulin/ErbB signaling in developmental myelin formation and nerve repair.
Birchmeier, C. and Bennett, D.L.H.
Current Topics in Developmental Biology 116
: 45-64.
2016
Current approaches toward quantitative mapping of the interactome.
Buntru, A., Trepte, P., Klockmeier, K., Schnoegl, S. and Wanker, E.E.
Frontiers in Genetics 7
: 74.
4 May 2016
Eyes on translation.
Chekulaeva, M. and Landthaler, M.
Molecular Cell 63
(6): 918-925.
15 September 2016
Circular RNAs in brain and other tissues: a functional enigma.
Chen, W. and Schuman, E.
Trends in Neurosciences 39
(9): 597-604.
September 2016
LRP2, an auxiliary receptor that controls sonic hedgehog signaling in development and disease.
Christ, A., Herzog, K. and Willnow, T.E.
Developmental Dynamics 245
(5): 569-579.
May 2016
The APOSTEL recommendations for reporting quantitative optical coherence tomography studies.
Cruz-Herranz, A., Balk, L.J., Oberwahrenbrock, T., Saidha, S., Martinez-Lapiscina, E.H., Lagreze, W.A., Schuman, J.S., Villoslada, P., Calabresi, P., Balcer, L., Petzold, A., Green, A.J., Paul, F., Brandt, A.U. and Albrecht, P.
Neurology 86
(24): 2303-2309.
14 June 2016
Anchoring a leviathan: how the nuclear membrane tethers the genome.
Czapiewski, R., Robson, M.I. and Schirmer, E.C.
Frontiers in Genetics 7
: 82.
6 May 2016
S100A4 in cancer metastasis: Wnt signaling-driven interventions for metastasis restriction.
Dahlmann, M., Kobelt, D., Walther, W., Mudduluru, G. and Stein, U.
Cancers 8
(6): 59.
20 June 2016
Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily.
Daumke, O. and Praefcke, G.J.
Biopolymers 105
(8): 580-593.
August 2016
Kaliopenic nephropathy revisited.
Elitok, S., Bieringer, M., Schneider, W. and Luft, F.C.
Clinical Kidney Journal 9
(4): 543-546.
August 2016
The translational potential of microRNAs as biofluid markers of urological tumours.
Fendler, A., Stephan, C., Yousef, G.M., Kristiansen, G. and Jung, K.
Nature Reviews Urology 13
(12): 734-752.
December 2016
Advanced light microscopy core facilities: Balancing service, science and career.
Ferrando-May, E., Hartmann, H., Reymann, J., Ansari, N., Utz, N., Fried, H.U., Kukat, C., Peychl, J., Liebig, C., Terjung, S., Laketa, V., Sporbert, A., Weidtkamp-Peters, S., Schauss, A., Zuschratter, W. and Avilov, S.
Microscopy Research and Technique 79
(6): 463-479.
June 2016
Contemporary use and results of intra-aortic balloon pump counterpulsation.
Gargiulo, G., Stabile, E., Perrino, C., Scudiero, F., Scudiero, L., Schiattarella, G.G., Franzone, A., Sannino, A., Giugliano, G., Trimarco, B. and Esposito, G.
Minerva Cardioangiologica 64
(1): 84-91.
February 2016
The role of microglia and macrophages in glioma maintenance and progression.
Hambardzumyan, D., Gutmann, D.H. and Kettenmann, H.
Nature Neuroscience 19
(1): 20-27.
January 2016
CMR first-pass perfusion for suspected inducible myocardial ischemia.
Hendel, R.C., Friedrich, M.G., Schulz-Menger, J., Zemmrich, C., Bengel, F., Berman, D.S., Camici, P.G., Flamm, S.D., Le Guludec, D., Kim, R., Lombardi, M., Mahmarian, J., Sechtem, U. and Nagel, E.
JACC: Cardiovascular Imaging 9
(11): 1338-1348.
7 November 2016
VRACs and other ion channels and transporters in the regulation of cell volume and beyond.
Jentsch, T.J.
Nature Reviews Molecular Cell Biology 17
(5): 293-307.
May 2016
VRAC: molecular identification as LRRC8 heteromers with differential functions.
Jentsch, T.J., Lutter, D., Planells-Cases, R., Ullrich, F. and Voss, F.K.
Pflugers Archiv 468
(3): 385-393.
March 2016
Prediction of activity related energy expenditure using accelerometer derived physical activity under free-living conditions-a systematic review.
Jeran, S., Steinbrecher, A. and Pischon, T.
International Journal of Obesity 40
(8): 1187-1197.
August 2016
Environmental factors in autoimmune diseases and their role in multiple sclerosis.
Jörg, S., Grohme, D.A., Erzler, M., Binsfeld, M., Haghikia, A., Müller, D.N., Linker, R.A. and Kleinewietfeld, M.
Cellular and Molecular Life Sciences 73
(24): 4611-4622.
December 2016
Diagnosis and treatment of cardiac echinococcosis.
Kahlfuss, S., Flieger, R.R., Roepke, T.K. and Yilmaz, K.
Heart 102
(17): 1348-1353.
September 2016
Genome wide conditional mouse knockout resources.
Kaloff, C., Anastassiadis, K., Ayadi, A., Baldock, R., Beig, J., Birling, M.C., Bradley, A., Brown, S.D.M., Buerger, A., Bushell, W., Chiani, F., Collins, F.S., Doe, B., Eppig, J.T., Finnell, R.H., Fletcher, C., Flicek, P., Fray, M., Friedel, R.H., Gambadoro, A., Gates, H., Hansen, J., Herault, Y., Hicks, G.G., Hoerlein, A., Hrabe de Angelis, M., Iyer, V., de Jong, P.J., Koscielny, G., Kuehn, R., Liu, P., Lloyd, K.C.K, Lopez, R.G., Marschall, S., Martinez, S., McKerlie, C., Meehan, T., von Melchner, H., Moore, M., Murray, S.A., Nagy, A., Nutter, L.M.J., Pavlovic, G., Pombero, A., Prosser, H., Ramirez-Solis, R., Ringwald, M., Rosen, B., Rosenthal, N., Rossant, J., Ruiz Noppinger, P., Ryder, E., Skarnes, W.C., Schick, J., Schnuetgen, F., Schofield, P., Seisenberger, C., Selloum, M., Smedley, D., Simpson, E.M., Stewart, A.F., Teboul, L., Tocchini Valentini, G.P., Valenzuela, D., West, A.P. and Wurst, W.
Drug Discovery Today: Disease Models 20
: 3-12.
2016
Neutral serine proteases of neutrophils.
Kettritz, R.
Immunological Reviews 273
(1): 232-248.
September 2016
Protein-protein interactions of PDE4 family members - Functions, interactions and therapeutic value.
Klussmann, E.
Cellular Signalling 28
(7): 713-718.
July 2016
Xenopus as a model system for studying pancreatic development and diabetes.
Kofent, J. and Spagnoli, F.M.
Seminars in Cell & Developmental Biology 51
: 106-116.
March 2016
Stem cells versus plasticity in liver and pancreas regeneration.
Kopp, J.L., Grompe, M. and Sander, M.
Nature Cell Biology 18
(3): 238-45.
March 2016
Cellular and system biology of memory: Timing, molecules, and beyond.
Korte, M. and Schmitz, D.
Physiological Reviews 96
(2): 647-693.
April 2016
Tomo-seq: A method to obtain genome-wide expression data with spatial resolution.
Kruse, F., Junker, J.P., van Oudenaarden, A. and Bakkers, J.
Methods in Cell Biology 135
: 299-307.
2016
Divergent transcription and epigenetic directionality of human promoters.
Lacadie, S.A., Ibrahim, M.M., Gokhale, S.A. and Ohler, U.
FEBS Journal 283
(23): 4214-4222.
December 2016
A clinical perspective: contribution of dysfunctional perivascular adipose tissue (PVAT) to cardiovascular risk.
Lian, X. and Gollasch, M.
Current Hypertension Reports 18
(11): 82.
November 2016
Emerging cellular and gene therapies for congenital anemias.
Ludwig, L.S., Khajuria, R.K. and Sankaran, V.G.
American Journal of Medical Genetics C 172C
(4): 332-348.
12 December 2016
Breaking TADs: how alterations of chromatin domains result in disease.
Lupiáñez, D.G., Spielmann, M. and Mundlos, S.
Trends in Genetics 32
(4): 225-237.
April 2016
Medical treatment of stable angina: a tailored therapeutic approach.
Manolis, A.J., Poulimenos, L.E., Ambrosio, G., Kallistratos, M.S., Lopez-Sendon, J., Dechend, R., Mancia, G. and Camm, A.J.
International Journal of Cardiology 220
: 445-453.
1 October 2016
New technologies for DNA analysis - a review of the READNA project.
McGinn, S., Bauer, D., Brefort, T., Dong, L., El-Sagheer, A., Elsharawy, A., Evans, G., Falk-Sörqvist, E., Forster, M., Fredriksson, S., Freeman, P., Freitag, C., Fritzsche, J., Gibson, S., Gullberg, M., Gut, M., Heath, S., Heath-Brun, I., Heron, A.J., Hohlbein, J., Ke, R., Lancaster, O., Le Reste, L., Maglia, G., Marie, R., Mauger, F., Mertes, F., Mignardi, M., Moens, L., Oostmeijer, J., Out, R., Pedersen, J.N., Persson, F., Picaud, V., Rotem, D., Schracke, N., Sengenes, J., Stähler, P.F., Stade, B., Stoddart, D., Teng, X., Veal, C.D., Zahra, N., Bayley, H., Beier, M., Brown, T., Dekker, C., Ekström, B., Flyvbjerg, H., Franke, A., Guenther, S., Kapanidis, A.N., Kaye, J., Kristensen, A., Lehrach, H., Mangion, J., Sauer, S., Schyns, E., Tost, J., van Helvoort, J.M.L.M., van der Zaag, P.J., Tegenfeldt, J.O., Brookes, A.J., Mir, K., Nilsson, M., Willcocks, J.P. and Gut, I.G.
New Biotechnology 33
(3): 311-330.
25 May 2016
Energy metabolism in neuronal/glial induction and iPSC-based modeling of brain disorders.
Mlody, B., Lorenz, C., Inak, G. and Prigione, A.
Seminars in Cell & Developmental Biology 52
: 102-109.
April 2016
Repositioning of drugs for intervention in tumor progression and metastasis: Old drugs for new targets.
Mudduluru, G., Walther, W., Kobelt, D., Dahlmann, M., Treese, C., Assaraf, Y.G. and Stein, U.
Drug Resistance Updates 26
: 10-27.
May 2016
Magnetic resonance imaging applications on infiltrative cardiomyopathies.
Muehlberg, F., Toepper, A., Fritschi, S., Prothmann, M. and Schulz-Menger, J.
Journal of Thoracic Imaging 31
(6): 336-347.
November 2016
W(h)ither human cardiac and body magnetic resonance at ultrahigh fields? technical advances, practical considerations, applications, and clinical opportunities.
Niendorf, T., Paul, K., Oezerdem, C., Graessl, A., Klix, S., Huelnhagen, T., Hezel, F., Rieger, J., Waiczies, H., Frahm, J., Nagel, A.M., Oberacker, E. and Winter, L.
NMR in Biomedicine 29
(9): 1173-1197.
September 2016
Sequence co-evolutionary information is a natural partner to minimally-frustrated models of biomolecular dynamics.
Noel, J.K., Morcos, F. and Onuchic, J.N.
F1000 Research 5
(F1000 Faculty Rev): 106.
26 January 2016
Therapeutic complement targeting in ANCA-associated vasculitides and thrombotic microangiopathy.
Novikov, P., Kozlovskaya, N., Moiseev, S., Shilov, E., Bobkova, I., Schreiber, A., Tsvetkov, D., Gollasch, M., Mah, N., El Amrani, K. and Kurtz, A.
Biomedicine Hub 1
(3): 453106.
13 December 2016
Vectors and strategies for nonviral cancer gene therapy.
Pahle, J. and Walther, W.
Expert Opinion on Biological Therapy 16
(4): 443-461.
April 2016
Pathology and MRI: exploring cognitive impairment in MS.
Paul, F.
Acta Neurologica Scandinavica 134
(Suppl 200): 24-33.
September 2016
IL-33 in T cell differentiation, function, and immune homeostasis.
Peine, M., Marek, R.M. and Loehning, M.
Trends in Immunology 37
(5): 321-333.
May 2016
Congenital coronary artery anomalies: a bridge from embryology to anatomy and pathophysiology-a position statement of the development, anatomy, and pathology ESC Working Group.
Perez-Pomares, J.M., de la Pompa, J.L., Franco, D., Henderson, D., Ho, S.Y., Houyel, L., Kelly, R.G., Sedmera, D., Sheppard, M., Sperling, S., Thiene, G., van den Hoff, M. and Basso, C.
Cardiovascular Research 109
(2): 204-216.
1 February 2016
How to manage the obese patient with cancer.
Renehan, A.G., Harvie, M., Cutress, R.I., Leitzmann, M., Pischon, T., Howell, S. and Howell, A.
Journal of Clinical Oncology 34
(35): 4284-4294.
10 December 2016
Macrophages and HIV-1: an unhealthy constellation.
Sattentau, Q.J. and Stevenson, M.
Cell Host & Microbe 19
(3): 304-310.
9 March 2016
Cardiovascular effects of histone deacetylase inhibitors epigenetic therapies: systematic review of 62 studies and new hypotheses for future research.
Schiattarella, G.G., Sannino, A., Toscano, E., Cattaneo, F., Trimarco, B., Esposito, G. and Perrino, C.
International Journal of Cardiology 219
: 396-403.
15 September 2016
Protein sorting gone wrong - VPS10P domain receptors in cardiovascular and metabolic diseases.
Schmidt, V. and Willnow, T.E.
Atherosclerosis 245
: 194-199.
February 2016
Recent advances in understanding apicomplexan parasites.
Seeber, F. and Steinfelder, S.
F1000Research 5
(F1000 Faculty Rev): 1369.
14 June 2016
Coevolution between the human microbiota and the epithelial immune system.
Sigal, M. and Meyer, T.F.
Digestive Diseases 34
(3): 190-193.
March 2016
Septins as modulators of endo-lysosomal membrane traffic.
Song, K., Russo, G. and Krauss, M.
Frontiers in Cell and Developmental Biology 4
: 124.
3 November 2016
XDSAPP2.0.
Sparta, K.M., Krug, M., Heinemann, U., Mueller, U. and Weiss, M.S.
Journal of Applied Crystallography 49
(3): 1085-1092.
June 2016
Actionable molecular biomarkers in primary brain tumors.
Staedtke, V., a Dzaye, O.D. and Holdhoff, M.
Trends in Cancer 2
(7): 338-349.
July 2016
Diplomatic assistance: can helminth-modulated macrophages act as treatment for inflammatory disease?
Steinfelder, S., O'Regan, N.L. and Hartmann, S.
PLoS Pathogens 12
(4): e1005480.
21 April 2016
Seasonality of food groups and total energy intake: a systematic review and meta-analysis.
Stelmach-Mardas, M., Kleiser, C., Uzhova, I., Penalvo, J.L., La Torre, G., Palys, W., Lojko, D., Nimptsch, K., Suwalska, A., Linseisen, J., Saulle, R., Colamesta, V. and Boeing, H.
European Journal of Clinical Nutrition 70
(6): 700-708.
June 2016
Bone marrow GvHD after allogeneic hematopoietic stem cell transplantation.
Szyska, M. and Na, I.K.
Frontiers in Immunology 7
: 118.
30 March 2016
Balancing wobbles in the body sodium.
Titze, J., Rakova, N., Kopp, C., Dahlmann, A., Jantsch, J. and Luft, F.C.
Nephrology Dialysis Transplantation 31
(7): 1078-1081.
July 2016
The Berlin Treatment Algorithm: recommendations for tailored innovative therapeutic strategies for multiple sclerosis-related fatigue.
Veauthier, C., Hasselmann, H., Gold, S.M. and Paul, F.
EPMA Journal 7
: 25.
24 November 2016
Therapie der Fatigue bei Multipler Sklerose: Ein Behandlungsalgorithmus [Therapy of fatigue in multiple sclerosis : a treatment algorithm].
Veauthier, C. and Paul, F.
Nervenarzt 87
(12): 1310-1321.
December 2016
The trafficking of the water channel aquaporin-2 in renal principal cells-a potential target for pharmacological intervention in cardiovascular diseases.
Vukićević, T., Schulz, M., Faust, D. and Klussmann, E.
Frontiers in Pharmacology 7
: 23.
11 February 2016
The basal chorionic trophoblast cell layer: an emerging coordinator of placenta development.
Walentin, K., Hinze, C. and Schmidt-Ott, K.M.
BioEssays 38
(3): 254-265.
March 2016
Magnetic resonance thermometry: methodology, pitfalls and practical solutions.
Winter, L., Oberacker, E., Paul, K., Ji, Y., Oezerdem, C., Ghadjar, P., Thieme, A., Budach, V., Wust, P. and Niendorf, T.
International Journal of Hyperthermia 32
(1): 63-75.
February 2016
Mechanisms of β-cell functional adaptation to changes in workload.
Wortham, M. and Sander, M.
Diabetes Obesity & Metabolism 18
(Suppl 1): 78-86.
September 2016
MAP kinase cascades in antigen receptor signaling and physiology.
Yasuda, T.
Current Topics in Microbiology and Immunology 393
: 211-231.
2016
Neurodermitis-Gene beeinflussen auch andere Allergien.
Zens, J.
Haut 27
(1): 16.
February 2016
Autophagy and immune senescence.
Zhang, H., Puleston, D.J. and Simon, A.K.
Trends in Molecular Medicine 22
(8): 671-686.
August 2016
Letter
Impact of FLT3-ITD location on sensitivity to TKI-therapy in vitro and in vivo.
Arreba-Tutusaus, P., Mack, T.S., Bullinger, L., Schnöder, T.M., Polanetzki, A., Weinert, S., Ballaschk, A., Wang, Z., Deshpande, A.J., Armstrong, S.A., Döhner, K., Fischer, T. and Heidel, F.H.
Leukemia 30
(5): 1220-1225.
May 2016
Strong impact of extramedullary involvement in high-risk AML patients with active disease receiving the FLAMSA conditioning regimen for HSCT.
Bohl, S., von Harsdorf, S., Mulaw, M., Hofmann, S., Babiak, A., Maier, C.P., Schnell, J., Hütter-Krönke, L.M., Scholl, K., Wais, V., Schlenk, R.F., Bullinger, L., Ringhoffer, M., Döhner, H., Bunjes, D., Bommer, M. and Kuchenbauer, F.
Bone Marrow Transplantation 51
(7): 994-996.
July 2016
T cell PTLD successfully treated with single-agent brentuximab vedotin first-line therapy.
Choi, M., Fink, S., Prasad, V., Anagnostopoulos, I., Reinke, P. and Schmitt, C.A.
Transplantation 100
(3): e8-e10.
March 2016
The impact of epistemological beliefs and cognitive ability on recall and critical evaluation of scientific information.
Feinkohl, I., Flemming, D., Cress, U. and Kimmerle, J.
Cognitive Processing 17
(2): 213-223.
May 2016
Radioimmunotherapy in relapsed/refractory mantle cell lymphoma patients: final results of a European MCL network phase II trial.
Ferrero, S., Pastore, A., Scholz, C.W., Forstpointner, R., Pezzutto, A., Bergmann, L., Truemper, L., Finke, J., Keller, U., Ghione, P., Passera, R., Hiddemann, W., Weigert, O., Unterhalt, M. and Dreyling, M.
Leukemia 30
(4): 984-987.
April 2016
Re: Sun-Kui Ke et al. TRiPping over vasotonus regulation in the lung.
Gollasch, M. and Kuebler, W.M.
Respiratory Physiology & Neurobiology 227
: 71-72.
15 June 2016
Crimea report leaves readers in the cold.
Goushcha, A., Goloverda, G.Z., Kotsyuba, O., Perepichka, D.F., Seumenicht, O. and Ladokhin, A.S.
Science 352
(6287): 780-781.
13 May 2016
Genetic causes of MCPH in consanguineous Pakistani families.
Kraemer, N., Picker-Minh, S., Abbasi, A.A., Froehler, S., Ninnemann, O., Khan, M.N., Ali, G., Chen, W. and Kaindl, A.M.
Clinical Genetics 89
(6): 744-745.
June 2016
MiR-139-5p is a potent tumor suppressor in adult acute myeloid leukemia.
Krowiorz, K., Ruschmann, J., Lai, C., Ngom, M., Maetzig, T., Martins, V., Scheffold, A., Schneider, E., Pochert, N., Miller, C., Palmqvist, L., Staffas, A., Mulaw, M., Bohl, S.R., Buske, C., Heuser, M., Kraus, J., O'Neill, K., Hansen, C.L., Petriv, O.I., Kestler, H., Döhner, H., Bullinger, L., Döhner, K., Humphries, R.K., Rouhi, A. and Kuchenbauer, F.
Blood Cancer Journal 6
(12): e508.
December 2016
Mutations in SEC24D cause autosomal recessive osteogenesis imperfecta.
Moosa, S., Chung, B.H.Y., Tung, J.Y.L., Altmüller, J., Thiele, H., Nürnberg, P., Netzer, C., Nishimura, G. and Wollnik, B.
Clinical Genetics 89
(4): 517-519.
April 2016
A novel homozygous PAM16 mutation in a patient with a milder phenotype and longer survival.
Moosa, S., Fano, V., Obregon, M.G., Altmüller, J., Thiele, H., Nürnberg, P., Nishimura, G. and Wollnik, B.
American Journal of Medical Genetics Part A 170
(9): 2436-2439.
September 2016
What do BOLD MR imaging changes in donors' remaining kidneys tell us?
Niendorf, T., Flemming, B., Evans, R.G. and Seeliger, E.
Radiology 281
(2): 653-655.
November 2016
Organ siderosis and hemophagocytosis during acute graft-versus-host disease.
Nogai, A., Shi, Y., Perez-Hernandez, D., Cordes, S., Mengwasser, J., Mertlitz, S., Riesner, K., Kalupa, M., Erdmann, J.H., Ziebig, R., Dittmar, G. and Penack, O.
Haematologica 101
(8): e344-e346.
August 2016
MicroRNA expression-based outcome prediction in acute myeloid leukemia: novel insights through cross-platform integrative analyses.
Shivarov, V., Dolnik, A., Lang, K.M., Krönke, J., Kuchenbauer, F., Paschka, P., Gaidzik, V.I., Döhner, H., Schlenk, R.F., Döhner, K. and Bullinger, L.
Haematologica 101
(11): e454-e456.
November 2016
Clinical impact of GATA2 mutations in acute myeloid leukemia patients harboring CEBPA mutations: a study of the AML study group.
Theis, F., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Weber, D., Bullinger, L., Heuser, M., Ganser, A., Thol, F., Schlegelberger, B., Göhring, G., Köhne, C.H., Germing, U., Brossart, P., Horst, H.A., Haase, D., Götze, K., Ringhoffer, M., Fiedler, W., Nachbaur, D., Kindler, T., Held, G., Lübbert, M., Wattad, M., Salih, H.R., Krauter, J., Döhner, H., Schlenk, R.F. and Döhner, K.
Leukemia 30
(11): 2248-2250.
November 2016
Editorial
KCNE2 and gastric cancer: bench to bedside.
Abbott, G.W. and Roepke, T.K.
Oncotarget 7
(14): 17286-17287.
5 April 2016
Examining topological domain influence on enhancer function.
Beagrie, R.A. and Pombo, A.
Developmental Cell 39
(5): 523-524.
5 December 2016
Orchestrating Wnt signalling for metabolic liver zonation.
Birchmeier, W.
Nature Cell Biology 18
(5): 463-465.
May 2016
Receptor combinations hone T-cell therapy.
Blankenstein, T.
Nature Biotechnology 34
(4): 389-391.
7 April 2016
Welcome to Biomedicine Hub.
Chan, J.Y.H., Chan, S.H.H., Cosci, F., Gardiner, D.M., Gollasch, M., Gwinn, M., Isgaard, J., Kalantar-Zadeh, K., Patrinos, G.P., Rubinstein, I., Schmid, M., Sherman, M., Simon, H.U., Stratakis, C.A., Tanner, M. and Zaenker, K.S.
Biomedicine Hub 1
(1): 1-2.
2016
Protein-mediated membrane remodeling.
Daumke, O. and Unger, V.M.
Journal of Structural Biology 196
(1): 1-2.
October 2016
Cancer cachexia-when proteasomal inhibition is not enough.
Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7
(3): 239-245.
June 2016
Blood flow boosts BMP signaling to keep vessels in shape.
Franco, C.A. and Gerhardt, H.
Journal of Cell Biology 214
(7): 793-795.
26 September 2016
Putting chromatin in its place: the pioneer factor NeuroD1 modulates chromatin state to drive cell fate decisions.
Glahs, A. and Zinzen, R.P.
EMBO Journal 35
(1): 1-3.
4 January 2016
Tumor necrosis factor-α, uterine natural killer cells, and pregnancy.
Golic, M., Luft, F.C. and Dechend, R.
Hypertension 68
(5): 1108-1109.
November 2016
FENS Forum 2018 in Berlin.
Kettenmann, H. and Pflueger, H.J.
Neuroforum 22
(4): 109-109.
December 2016
The case: nonneurological tetraplegia.
Kettritz, R., Gollasch, B., Zaks, M. and Luft, F.C.
Kidney International 89
(3): 727-728.
March 2016
An osteoarthritis triple play.
Luft, F.C.
Journal of Molecular Medicine 94
(7): 735-737.
July 2016
ATP-ADP translocase and effects on ischemic heart.
Luft, F.C.
Journal of Molecular Medicine 94
(6): 609-611.
June 2016
A visionary scientist selects clinicians for clinical research.
Luft, F.C.
Journal of Molecular Medicine 94
(4): 371-372.
April 2016
Hypoxemia as a model for high altitude and cardiovascular risk reduction.
Luft, F.C.
Journal of Molecular Medicine 94
(3): 247-249.
March 2016
Coming of age with maintained cardiovascular health.
Luft, F.C.
Journal of the American Society of Hypertension 10
(1): 16-21.
January 2016
High-mobility group box 1 protein, angiotensins, ACE2, and target organ damage.
Luft, F.C.
Journal of Molecular Medicine 94
(1): 1-3.
January 2016
Could licorice lick inflammasomes?
Luft, F.C.
Journal of Molecular Medicine 94
(12): 1309-1311.
December 2016
Asian flushing presents opportunities for disease prevention.
Luft, F.C.
Journal of Molecular Medicine 94
(11): 1195-1197.
November 2016
NFAT5 moves to Fat City.
Luft, F.C.
Journal of Molecular Medicine 94
(9): 967-969.
September 2016
Risk factors: evolving epidemiology of sodium intake and CVD.
Luft, F.C.
Nature Reviews Cardiology 13
(8): 445-446.
August 2016
11-β hydroxysteroid dehydrogenase-2 and salt-sensitive hypertension.
Luft, F.C.
Circulation 133
(14): 1335-1337.
5 April 2016
A glycolytic solution for pluripotent stem cells.
Mlody, B. and Prigione, A.
Cell Stem Cell 19
(4): 419-420.
6 October 2016
From ultrahigh to extreme field magnetic resonance: where physics, biology and medicine meet.
Niendorf, T., Barth, M., Kober, F. and Trattnig, S.
Magnetic Resonance Materials in Physics Biology and Medicine 29
(3): 309-311.
June 2016
What is the future of proof of concept studies in multiple sclerosis?
Paul, F.
Lancet Neurology 15
(11): 1107-1109.
October 2016
A mitochondrial view of cell fate.
Prigione, A.
Seminars in Cell & Developmental Biology 52
: 66-67.
April 2016
Preface.
Rickert-Sperling, S., Kelly, R.G. and Driscoll, D.J.
Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways
: ix-x.
2016
Eosinophils and mast cells: a lineage apart.
Sarrazin, S. and Sieweke, M.H.
Nature Immunology 17
(6): 609-611.
19 May 2016
The persistent dynamic secrets of senescence.
Schmitt, C.A.
Nature Cell Biology 18
(9): 913-915.
September 2016
Koronare Herzkrankheit (KHK): Kardiale MRT hilft, unnoetige Herzkatheter zu vermeiden [Cardiovascular magnetic resonance helps to prevent unnecessary angiographies].
Schulz-Menger, J.
Deutsche Medizinische Wochenschrift 141
(23): 1666.
November 2016
EPA and/or DHA? A test question on the principles and opportunities in utilizing the therapeutic potential of omega-3 fatty acids.
Schunck, W.H.
Journal of Lipid Research 57
(9): 1608-1611.
September 2016
Aquaporin-4 IgG autoimmune syndrome and immunoreactivity associated with thyroid cancer.
Soelberg, K., Larsen, S.R., Moerch, M.T., Thomassen, M., Brusgaard, K., Paul, F., Smith, T.J., Godballe, C., Grauslund, J., Lillevang, S.T. and Asgari, N.
Neurology Neuroimmunology & Neuroinflammation 3
(4): e252.
August 2016
Nikolai V. Timofeeff-Ressovsky and the Campus Berlin-Buch.
Sommer, T.
Genetics, Evolution and Radiation
: ix-xi.
2016
TT2016 meeting report on the 13th Transgenic Technology meeting in Prague, Czech Republic.
Tamowski, S., Luo, J., Kanzler, B., Whitelaw, B., Crispo, M., Doglio, L., Jerchow, B. and Parker-Thornburg, J.
Transgenic Research 25
(4): 553-559.
August 2016
High T gives β cells a boost.
Wortham, M. and Sander, M.
Cell Metabolism 23
(5): 761-3.
10 May 2016
The Case : a handful of hypertension.
van den Born, B.J.H., Oskam, L.C., Zidane, M., Schaechterle, C., Klussmann, E., Bähring, S. and Luft, F.C.
Kidney International 90
(4): 911-913.
October 2016
Comment
Aging vs. rejuvenation: reprogramming to iPSCs does not turn back the clock for somatic mitochondrial DNA mutations.
Lorenz, C. and Prigione, A.
Stem Cell Investigation 3
: 43.
September 2016
Other
Stefan Jentsch (1955-2016) Obituary.
Sommer, T., Hoppe, T. and Rape, M.
Cell Press.
15 December 2016
Stefan Jentsch (1955-2016) Obituary.
Sommer, T., Hoppe, T. and Rape, M.
Cell Press.
15 December 2016
This list was generated on Sat Dec 21 06:37:50 2024 UTC.