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2018

Influence of estrogen on individual exercise motivation and bone protection in ovariectomized rats.
Müller, S.T. and Keiler, A.M. and Kräker, K. and Zierau, O. and Bernhardt, R.
Laboratory Animals 52 (5): 479-489. October 2018

High-salt diet causes expansion of the lymphatic network and increased lymph flow in skin and muscle of rats.
Karlsen, T.V. and Nikpey, E. and Han, J. and Reikvam, T. and Rakova, N. and Castorena-Gonzalez, J.A. and Davis, M.J. and Titze, J.M. and Tenstad, O. and Wiig, H.
Arteriosclerosis Thrombosis and Vascular Biology 38 (9): 2054-2064. September 2018

Soluble B7-H4 blood serum levels are elevated in women at high risk for preeclampsia in the first trimester, as well as in patients with confirmed preeclampsia.
Mach, P. and Nolte-Boenigk, L. and Droste, L. and Fox, L. and Frank, M. and Schmidt, B. and Herse, F. and Verlohren, S. and Wicherek, L. and Iannaccone, A. and Birdir, C. and Andrikos, D. and Kimmig, R. and Gellhaus, A. and Köninger, A.
American Journal of Reproductive Immunology 80 (3): e12988. September 2018

Scientists on the Spot: Salt, the microbiome, and cardiovascular diseases.
Czesnikiewicz-Guzik, M. and Mueller, D.N.
Cardiovascular Research 114 (10): e72-e73. 1 August 2018

Duration of storage influences the hemoglobin rising effect of red blood cells in patients undergoing major abdominal surgery.
Hunsicker, O. and Hessler, K. and Krannich, A. and Boemke, W. and Braicu, I. and Sehouli, J. and Meyer, O. and Pruß, A. and Spies, C. and Feldheiser, A.
Transfusion 58 (8): 1870-1880. August 2018

SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling.
Voelkl, J. and Luong, T.T. and Tuffaha, R. and Musculus, K. and Auer, T. and Lian, X. and Daniel, C. and Zickler, D. and Boehme, B. and Sacherer, M. and Metzler, B. and Kuhl, D. and Gollasch, M. and Amann, K. and Müller, D.N. and Pieske, B. and Lang, F. and Alesutan, I.
Journal of Clinical Investigation 128 (7): 3024-3040. 2 July 2018

Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats.
Morgan, H.L. and Butler, E. and Ritchie, S. and Herse, F. and Dechend, R. and Beattie, E. and McBride, M.W. and Graham, D.
Hypertension 72 (1): 208-2018. July 2018

Sodium chloride triggers Th17 mediated autoimmunity.
Haase, S. and Wilck, N. and Kleinewietfeld, M. and Müller, D.N. and Linker, R.A.
Journal of Neuroimmunology 30 June 2018 (In Press)

Cystathionine γ-lyase-produced hydrogen sulfide controls endothelial NO bioavailability and blood pressure.
Szijártó, I.A. and Markó, L. and Filipovic, M.R. and Miljkovic, J.L. and Tabeling, C. and Tsvetkov, D. and Wang, N. and Rabelo, L.A. and Witzenrath, M. and Diedrich, A. and Tank, J. and Akahoshi, N. and Kamata, S. and Ishii, I. and Gollasch, M.
Hypertension 71 (6): 1210-1217. June 2018

Impacts of microbiome metabolites on immune regulation and autoimmunity.
Haase, S. and Haghikia, A. and Wilck, N. and Müller, D.N. and Linker, R.A.
Immunology 154 (2): 230-238. June 2018

The role of PAR1 autoantibodies in patients with primary epithelial ovarian cancer.
Kreienbring, K. and Franz, A. and Richter, R. and Dragun, D. and Heidecke, H. and Müller, D. and Mentze, M. and Dechend, R. and Sehouli, J. and Braicu, E.I.
Anticancer Research 38 (6): 3619-3625. June 2018

Continuous blood glucose monitoring reveals enormous circadian variations in pregnant diabetic rats.
Golic, M. and Kräker, K. and Fischer, C. and Alenina, N. and Haase, N. and Herse, F. and Schütte, T. and Henrich, W. and Müller, D.N. and Busjahn, A. and Bader, M. and Dechend, R.
Frontiers in Endocrinology 9 : 271. 29 May 2018

Diabetes mellitus in pregnancy leads to growth restriction and epigenetic modification of the Srebf2 gene in rat fetuses.
Golic, M. and Stojanovska, V. and Bendix, I. and Wehner, A. and Herse, F. and Haase, N. and Kräker, K. and Fischer, C. and Alenina, N. and Bader, M. and Schütte, T. and Schuchardt, M. and van der Giet, M. and Henrich, W. and Muller, D.N. and Felderhoff-Müser, U. and Scherjon, S. and Plösch, T. and Dechend, R.
Hypertension 71 (5): 911-920. May 2018

Downregulation of p53 drives autophagy during human trophoblast differentiation.
Gauster, M. and Maninger, S. and Siwetz, M. and Deutsch, A. and El-Heliebi, A. and Kolb-Lenz, D. and Hiden, U. and Desoye, G. and Herse, F. and Prokesch, A.
Cellular and Molecular Life Sciences 75 (10): 1839-1855. May 2018

Transient receptor potential vanilloid 4 channel deficiency aggravates tubular damage after acute renal ischaemia reperfusion.
Mannaa, M. and Markó, L. and Balogh, A. and Vigolo, E. and N'diaye, G. and Kaßmann, M. and Michalick, L. and Weichelt, U. and Schmidt-Ott, K.M. and Liedtke, W.B. and Huang, Y. and Müller, D.N. and Kuebler, W.M. and Gollasch, M.
Scientific Reports 8 (1): 4878. 20 March 2018

Nitric oxide-sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction.
Wilck, N. and Markó, L. and Balogh, A. and Kräker, K. and Herse, F. and Bartolomaeus, H. and Szijártó, I.A. and Gollasch, M. and Reichhart, N. and Strauss, O. and Heuser, A. and Brockschnieder, D. and Kretschmer, A. and Lesche, R. and Sohler, F. and Stasch, J.P. and Sandner, P. and Luft, F. and Müller, D.N. and Dechend, R. and Haase, N.
JCI Insight 3 (4): e96006. 22 February 2018

Dieter Klaus und die Bluthochdruckforschung.
Gollasch, M. and Tsvetkov, D. and Müller, D.
Nieren- und Hochdruckkrankheiten 47 (1): 40-46. January 2018

2017

Salt-responsive gut commensal modulates T(H)17 axis and disease.
Wilck, N. and Matus, M.G. and Kearney, S.M. and Olesen, S.W. and Forslund, K. and Bartolomaeus, H. and Haase, S. and Mähler, A. and Balogh, A. and Markó, L. and Vvedenskaya, O. and Kleiner, F.H. and Tsvetkov, D. and Klug, L. and Costea, P.I. and Sunagawa, S. and Maier, L. and Rakova, N. and Schatz, V. and Neubert, P. and Frätzer, C. and Krannich, A. and Gollasch, M. and Grohme, D.A. and Côrte-Real, B.F. and Gerlach, R.G. and Basic, M. and Typas, A. and Wu, C. and Titze, J.M. and Jantsch, J. and Boschmann, M. and Dechend, R. and Kleinewietfeld, M. and Kempa, S. and Bork, P. and Linker, R.A. and Alm, E.J. and Müller, D.N.
Nature 551 (7682): 585-589. 30 November 2017

Disturbed placental imprinting in preeclampsia leads to altered expression of DLX5, a human-specific early trophoblast marker.
Zadora, J. and Singh, M. and Herse, F. and Przybyl, L. and Haase, N. and Golic, M. and Yung, H.W. and Huppertz, B. and Cartwright, J.E. and Whitley, G.S. and Johnsen, G.M. and Levi, G. and Isbruch, A. and Schulz, H. and Luft, F.C. and Müller, D.N. and Staff, A.C. and Hurst, L.D. and Dechend, R. and Izsvák, Z.
Circulation 136 (19): 1824-1839. 7 November 2017

Proliferation of endogenous regulatory T cells improve the pathophysiology associated with placental ischaemia of pregnancy.
Ibrahim, T. and Przybyl, L. and Harmon, A.C. and Amaral, L.M. and Faulkner, J.L. and Cornelius, D. and Cunningham, M.W. and Hünig, T. and Herse, F. and Wallukat, G. and Dechend, R. and LaMarca, B.
American Journal of Reproductive Immunology 78 (5): e12724. November 2017

Immunoproteasome subunit β5i/LMP7-deficiency in atherosclerosis.
Hewing, B. and Ludwig, A. and Dan, C. and Poetzsch, M. and Hannemann, C. and Petry, A. and Lauer, D. and Görlach, A. and Kaschina, E. and Müller, D.N. and Baumann, G. and Stangl, V. and Stangl, K. and Wilck, N.
Scientific Reports 7 (1): 13342. 17 October 2017

Soluble (pro)renin receptor in preeclampsia and diabetic pregnancies.
Sugulle, M. and Heidecke, H. and Maschke, U. and Herse, F. and Danser, A.H.J. and Mueller, D.N. and Staff, A.C. and Dechend, R.
Journal of the American Society of Hypertension 11 (10): 644-652. October 2017

Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation.
Hammer, A. and Schliep, A. and Jörg, S. and Haghikia, A. and Gold, R. and Kleinewietfeld, M. and Müller, D.N. and Linker, R.A.
Journal of Neuroinflammation 14 (1): 184. 12 September 2017

Antibodies to signaling molecules and receptors in Alzheimer's disease are associated with psychomotor slowing, depression, and poor visuospatial function.
Giil, L.M. and Vedeler, C.A. and Kristoffersen, E.K. and Nordrehaug, J.E. and Heidecke, H. and Dechend, R. and Schulze-Forster, K. and Muller, D.N. and von Goetze, V.S. and Cabral-Marques, O. and Riemekasten, G. and Vogelsang, P. and Nygaard, S. and Lund, A. and Aarsland, D.
Journal of Alzheimer's Disease 59 (3): 929-939. 29 July 2017

Placental DAPK1 and autophagy marker LC3B-II are dysregulated by TNF-α in a gestational age-dependent manner.
Prokesch, A. and Blaschitz, A. and Bauer, T. and Moser, G. and Hiden, U. and Zadora, J. and Dechend, R. and Herse, F. and Gauster, M.
Histochemistry and Cell Biology 147 (6): 695-705. June 2017

Placental-specific overexpression of sFlt-1 alters trophoblast differentiation and nutrient transporter expression in an IUGR mouse model.
Kuehnel, E. and Kleff, V. and Stojanovska, V. and Kaiser, S. and Waldschuetz, R. and Herse, F. and Ploesch, T. and Winterhager, E. and Gellhaus, A.
Journal of Cellular Biochemistry 118 (6): 1316-1329. June 2017

High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.
Kitada, K. and Daub, S. and Zhang, Y. and Klein, J. D. and Nakano, D. and Pedchenko, T. and Lantier, L. and LaRocque, L.M. and Marton, A. and Neubert, P. and Schröder, A. and Rakova, N. and Jantsch, J. and Dikalova, A.E. and Dikalov, S.I. and Harrison, D.G. and Müller, D.N. and Nishiyama, A. and Rauh, M. and Harris, R. C. and Luft, F.C. and Wassermann, D.H. and Sands, J.M. and Titze, J.
Journal of Clinical Investigation 127 (5): 1944-1959. 1 May 2017

Increased salt consumption induces body water conservation and decreases fluid intake.
Rakova, N. and Kitada, K. and Lerchl, K. and Dahlmann, A. and Birukov, A. and Daub, S. and Kopp, C. and Pedchenko, T. and Zhang, Y. and Beck, L. and Johannes, B. and Marton, A. and Müller, D.N. and Rauh, M. and Luft, F.C. and Titze, J.
Journal of Clinical Investigation 127 (5): 1932-1943. 1 May 2017

Increased placental sFlt-1 but unchanged PlGF expression in late-onset preeclampsia.
Ehrlich, L. and Hoeller, A. and Golic, M. and Herse, F. and Perschel, F.H. and Henrich, W. and Dechend, R. and Huppertz, B. and Verlohren, S.
Hypertension in Pregnancy 36 (2): 175-185. May 2017

Placental expression of sFlt-1 and PlGF in early preeclampsia vs. early IUGR vs. age-matched healthy pregnancies.
Hoeller, A. and Ehrlich, L. and Golic, M. and Herse, F. and Perschel, F.H. and Siwetz, M. and Henrich, W. and Dechend, R. and Huppertz, B. and Verlohren, S.
Hypertension in Pregnancy 36 (2): 151-160. May 2017

Protective function of ahnak1 in vascular healing after wire injury.
Haase, N. and Rüder, C. and Haase, H. and Kamann, S. and Kouno, M. and Morano, I. and Dechend, R. and Zohlnhöfer, D. and Haase, T.
Journal of Vascular Research 54 (3): 131-142. May 2017

Salt sensitivity of angiogenesis inhibition-induced blood pressure rise: role of interstitial sodium accumulation?
Lankhorst, S. and Severs, D. and Markó, L. and Rakova, N. and Titze, J. and Müller, D.N. and Danser, A.H.J. and van den Meiracker, A.H.
Hypertension 69 (5): 919-926. May 2017

The effect of low-dose proteasome inhibition on pre-existing atherosclerosis in LDL receptor-deficient mice.
Wilck, N. and Fechner, M. and Dan, C. and Stangl, V. and Stangl, K. and Ludwig, A.
International Journal of Molecular Sciences 18 (4): 781. 7 April 2017

Na(+) deposition in the fibrotic skin of systemic sclerosis patients detected by (23)Na-magnetic resonance imaging.
Kopp, C. and Beyer, C. and Linz, P. and Dahlmann, A. and Hammon, M. and Jantsch, J. and Neubert, P. and Rosenhauer, D. and Müller, D.N. and Cavallaro, A. and Eckardt, K.U. and Schett, G. and Luft, F.C. and Uder, M. and Distler, J.H.W. and Titze, J.
Rheumatology 56 (4): 556-560. 1 April 2017

High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph.
Nikpey, E. and Karlsen, T.V. and Rakova, N. and Titze, J.M. and Tenstad, O. and Wiig, H.
Hypertension 69 (4): 660-668. April 2017

Elementary immunology: Na(+) as a regulator of immunity.
Schatz, V. and Neubert, P. and Schröder, A. and Binger, K. and Gebhard, M. and Müller, D.N. and Luft, F.C. and Titze, J. and Jantsch, J.
Pediatric Nephrology 32 (2): 201-210. February 2017

The TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knockdown.
Reichhart, N. and Crespo-Garcia, S. and Haase, N. and Golic, M. and Skosyrski, S. and Rübsam, A. and Herrspiegel, C. and Kociok, N. and Alenina, N. and Bader, M. and Dechend, R. and Strauss, O. and Joussen, A.M.
Diabetologia 60 (1): 202-211. January 2017

2016

Role of the receptor Mas in macrophage-mediated inflammation in vivo.
Hammer, A. and Yang, G. and Friedrich, J. and Kovacs, A. and Lee, D.H. and Grave, K. and Jörg, S. and Alenina, N. and Grosch, J. and Winkler, J. and Gold, R. and Bader, M. and Manzel, A. and Rump, L.C. and Müller, D.N. and Linker, R.A. and Stegbauer, J.
Proceedings of the National Academy of Sciences of the United States of America 113 (49): 14109-14114. 6 December 2016

Reduced uterine perfusion pressure T-helper 17 cells cause pathophysiology associated with preeclampsia during pregnancy.
Cornelius, D.C. and Amaral, L.M. and Wallace, K. and Campbell, N. and Thomas, A.J. and Scott, J. and Herse, F. and Wallukat, G. and Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 311 (6): R1192-R1199. 1 December 2016

Environmental factors in autoimmune diseases and their role in multiple sclerosis.
Jörg, S. and Grohme, D.A. and Erzler, M. and Binsfeld, M. and Haghikia, A. and Müller, D.N. and Linker, R.A. and Kleinewietfeld, M.
Cellular and Molecular Life Sciences 73 (24): 4611-4622. December 2016

Tumor necrosis factor-α, uterine natural killer cells, and pregnancy.
Golic, M. and Luft, F.C. and Dechend, R.
Hypertension 68 (5): 1108-1109. November 2016

Aptamer BC 007 - a broad spectrum neutralizer of pathogenic autoantibodies against G-protein-coupled receptors.
Haberland, A. and Holtzhauer, M. and Schlichtiger, A. and Bartel, S. and Schimke, I. and Mueller, J. and Dandel, M. and Luppa, P.B. and Wallukat, G.
European Journal of Pharmacology 789 : 37-45. 15 October 2016

Natural killer cell reduction and uteroplacental vasculopathy.
Golic, M. and Haase, N. and Herse, F. and Wehner, A. and Vercruysse, L. and Pijnenborg, R. and Balogh, A. and Saether, P.C. and Dissen, E. and Luft, F.C. and Przybyl, L. and Park, J.K. and Alnaes-Katjavivi, P. and Staff, A.C. and Verlohren, S. and Henrich, W. and Muller, D.N. and Dechend, R.
Hypertension 68 (4): 964-973. October 2016

The association between angiogenic markers and fetal sex: implications for preeclampsia research.
Andersen, L.B. and Jørgensen, J.S. and Herse, F. and Andersen, M.S. and Christesen, H.T. and Dechend, R.
Journal of Reproductive Immunology 117 : 24-29. September 2016

Tubular epithelial NF-κB activity regulates ischemic AKI.
Markó, L. and Vigolo, E. and Hinze, C. and Park, J.K. and Roël, G. and Balogh, A. and Choi, M. and Wübken, A. and Cording, J. and Blasig, I.E. and Luft, F.C. and Scheidereit, C. and Schmidt-Ott, K.M. and Schmidt-Ullrich, R. and Müller, D.N.
Journal of the American Society of Nephrology 27 (9): 2658-2669. September 2016

Activation of peroxisome proliferator-activated receptor-δ as novel therapeutic strategy to prevent in-stent restenosis and stent thrombosis.
Hytönen, J. and Leppänen, O. and Braesen, J.H. and Schunck, W.H. and Mueller, D. and Jung, F. and Mrowietz, C. and Jastroch, M. and von Bergwelt-Baildon, M. and Kappert, K. and Heuser, A. and Drenckhahn, J.D. and Pieske, B. and Thierfelder, L. and Ylä-Herttuala, S. and Blaschke, F.
Arteriosclerosis Thrombosis and Vascular Biology 36 (8): 1534-1548. August 2016

Hypertensive retinopathy in a transgenic angiotensin-based model.
Reichhart, N. and Haase, N. and Crespo-Garcia, S. and Skosyrski, S. and Herrspiegel, C. and Kociok, N. and Fuchshofer, R. and Dillinger, A. and Poglitsch, M. and Müller, D.N. and Joussen, A.M. and Luft, F.C. and Dechend, R. and Strauß, O.
Clinical Science 130 (13): 1075-1088. 1 July 2016

Ultra-Long-term human salt balance studies reveal interrelations between sodium, potassium, and chloride intake and excretion.
Birukov, A. and Rakova, N. and Lerchl, K. and Olde Engberink, R.H.G. and Johannes, B. and Wabel, P. and Moissl, U. and Rauh, M. and Luft, F.C. and Titze, J.
American Journal of Clinical Nutrition 104 (1): 49-57. July 2016

Vitamin D depletion does not affect key aspects of the preeclamptic phenotype in a transgenic rodent model for preeclampsia.
Andersen, L.B. and Golic, M. and Przybyl, L. and Sorensen, G.L. and Jørgensen, J.S. and Fruekilde, P. and von Versen-Höynck, F. and Herse, F. and Højskov, C.S. and Dechend, R. and Christesen, H.T. and Haase, N.
Journal of the American Society of Hypertension 10 (7): 597-607.e1. July 2016

CD74-downregulation of placental macrophage-trophoblastic interactions in preeclampsia.
Przybyl, L. and Haase, N. and Golic, M. and Rugor, J. and Solano, M.E. and Arck, P.C. and Gauster, M. and Huppertz, B. and Emontzpohl, C. and Stoppe, C. and Bernhagen, J. and Leng, L. and Bucala, R. and Schulz, H. and Heuser, A. and Weedon-Fekjær, S. and Johnsen, G.M. and Peetz, D. and Luft, F.C. and Staff, A.C. and Müller, D.N. and Dechend, R. and Herse, F.
Circulation Research 119 (1): 55-68. 24 June 2016

Role of cystathionine gamma-lyase in immediate renal impairment and inflammatory response in acute ischemic kidney injury.
Markó, L. and Szijártó, I.A. and Filipovic, M.R. and Kaßmann, M. and Balogh, A. and Park, J.K. and Przybyl, L. and N'diaye, G. and Krämer, S. and Anders, J. and Ishii, I. and Müller, D.N. and Gollasch, M.
Scientific Reports 6 : 27517. 8 June 2016

High salt drives Th17 responses in experimental autoimmune encephalomyelitis without impacting myeloid dendritic cells.
Jörg, S. and Kissel, J. and Manzel, A. and Kleinewietfeld, M. and Haghikia, A. and Gold, R. and Müller, D.N. and Linker, R.A.
Experimental Neurology 279 : 212-222. May 2016

Relaxin treatment in an Ang-II-based transgenic reeclamptic-rat model.
Haase, N. and Golic, M. and Herse, F. and Rugor, J. and Linz, D. and Solano, M.E. and Müller, D.N. and Dechend, R.
PLoS ONE 11 (3): e0150743. 10 March 2016

Vitamin D supplementation improves pathophysiology in a rat model of preeclampsia.
Faulkner, J.L. and Cornelius, D.C. and Amaral, L.M. and Harmon, A.C. and Cunningham, M.W. and Darby, M.M. and Ibrahim, T. and Thomas, D.S. and Herse, F. and Wallukat, G. and Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 310 (4): R346-R354. 15 February 2016

Convergent evolution within CEA gene families in mammals: hints for species-specific selection pressures.
Kammerer, R. and Herse, F. and Zimmermann, W.
In: Evolutionary Biology : Convergent Evolution, Evolution of Complex Traits, Concepts and Methods. Springer International Publishing, Switzerland, 37-53. ISBN 978-3-319-41323-5 2016

Predictive and prognostic value of sPRR in patients with primary epithelial ovarian cancer.
Kreienbring, K. and Franz, A. and Richter, R. and Dragun, D. and Heidecke, H. and Dechend, R. and Mueller, D.N. and Sehouli, J. and Braicu, E.I.
Analytical Cellular Pathology 2016 : 6845213. 2016

2015

Blockade of CD40 ligand for intercellular communication reduces hypertension, placental oxidative stress, and AT1-AA in response to adoptive transfer of CD4(+) T lymphocytes from RUPP rats.
Cornelius, D.C. and Castillo, J. and Porter, J. and Amaral, L.M. and Campbell, N. and Paige, A. and Thomas, A.J. and Harmon, A. and Cunningham, M.W. and Wallace, K. and Herse, F. and Wallukat, G. and Dechend, R. and LaMarca, B.D.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 309 (10): R1243-R1250. 15 November 2015

High salt reduces the activation of IL-4- and IL-13-stimulated macrophages.
Binger, K.J. and Gebhardt, M. and Heinig, M. and Rintisch, C. and Schroeder, A. and Neuhofer, W. and Hilgers, K. and Manzel, A. and Schwartz, C. and Kleinewietfeld, M. and Voelkl, J. and Schatz, V. and Linker, R.A. and Lang, F. and Voehringer, D. and Wright, M.D. and Hubner, N. and Dechend, R. and Jantsch, J. and Titze, J. and Müller, D.N.
Journal of Clinical Investigation 125 (11): 4223-4238. 2 November 2015

Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine.
Haghikia, A. and Jörg, S. and Duscha, A. and Berg, J. and Manzel, A. and Waschbisch, A. and Hammer, A. and Lee, D.H. and May, C. and Wilck, N. and Balogh, A. and Ostermann, A.I. and Schebb, N.H. and Akkad, D.A. and Grohme, D.A. and Kleinewietfeld, M. and Kempa, S. and Thöne, J. and Demir, S. and Müller, D.N. and Gold, R. and Linker, R.A.
Immunity 43 (4): 817-829. 20 October 2015

An increased population of regulatory T cells improves the pathophysiology of placental ischemia in a rat model of preeclampsia.
Cornelius, D.C. and Amaral, L.M. and Harmon, A. and Wallace, K. and Thomas, A.J. and Campbell, N. and Scott, J. and Herse, F. and Haase, N. and Moseley, J. and Wallukat, G. and Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 309 (8): R884-R891. 15 October 2015

Increased apoptosis, altered oxygen signaling, and antioxidant defenses in first-trimester pregnancies with high-resistance uterine artery blood flow.
Leslie, K. and Whitley, G.S.J. and Herse, F. and Dechend, R. and Ashton, S.V. and Laing, K. and Thilaganathan, B. and Cartwright, J.E.
American Journal of Pathology 185 (10): 2731-2741. October 2015

IL-10 supplementation increases Tregs and decreases hypertension in the RUPP rat model of preeclampsia.
Harmon, A. and Cornelius, D. and Amaral, L. and Paige, A. and Herse, F. and Ibrahim, T. and Wallukat, G. and Faulkner, J. and Moseley, J. and Dechend, R. and LaMarca, B.
Hypertension in Pregnancy 34 (3): 291-306. August 2015

New role for the (pro)renin receptor in T cell development.
Geisberger, S. and Maschke, U. and Gebhardt, M. and Kleinewietfeld, M. and Manzel, A. and Linker, R.A. and Chidgey, A. and Dechend, R. and Nguyen, G. and Daumke, O. and Muller, D.N. and Wright, M.D. and Binger, K.J.
Blood 126 (4): 504-507. 23 July 2015

Exacerbation of acute kidney injury by bone marrow stromal cells from rats with persistent renin-angiotensin system activation.
Kankuri, E. and Mervaala, E.E. and Storvik, M. and Ahola, A.M.J. and Levijoki, J. and Müller, D.N. and Finckenberg, P. and Mervaala, E.M.
Clinical Science 128 (11): 735-747. 1 June 2015

Placental fractalkine mediates adhesion of THP-1 monocytes to villous trophoblast.
Siwetz, M. and Sundl, M. and Kolb, D. and Hiden, U. and Herse, F. and Huppertz, B. and Gauster, M.
Histochemistry and Cell Biology 143 (6): 565-574. June 2015

Regulatory T cells ameliorate intrauterine growth retardation in a transgenic rat model for preeclampsia.
Przybyl, L. and Ibrahim, T. and Haase, N. and Golic, M. and Rugor, J. and Luft, F.C. and Bendix, I. and Serdar, M. and Wallukat, G. and Staff, A.C. and Müller, D.N. and Hünig, T. and Felderhoff-Müser, U. and Herse, F. and LaMarca, B. and Dechend, R.
Hypertension 65 (6): 1298-1306. June 2015

Placental fractalkine is up-regulated in severe early-onset preeclampsia.
Siwetz, M. and Dieber-Rotheneder, M. and Cervar-Zivkovic, M. and Kummer, D. and Kremshofer, J. and Weiss, G. and Herse, F. and Huppertz, B. and Gauster, M.
American Journal of Pathology 185 (5): 1334-1343. May 2015

Cutaneous Na(+) storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense.
Jantsch, J. and Schatz, V. and Friedrich, D. and Schröder, A. and Kopp, C. and Siegert, I. and Maronna, A. and Wendelborn, D. and Linz, P. and Binger, K.J. and Gebhardt, M. and Heinig, M. and Neubert, P. and Fischer, F. and Teufel, S. and David, J.P. and Neufert, C. and Cavallaro, A. and Rakova, N. and Küper, C. and Beck, F.X. and Neuhofer, W. and Muller, D.N. and Schuler, G. and Uder, M. and Bogdan, C. and Luft, F.C. and Titze, J.
Cell Metabolism 21 (3): 493-501. 3 March 2015

Sodium chloride, SGK1, and Th17 activation.
Binger, K.J. and Linker, R.A. and Muller, D.N. and Kleinewietfeld, M.
Pfluegers Archiv European Journal of Physiology 467 (3): 543-550. March 2015

Magnetic resonance-determined sodium removal from tissue stores in hemodialysis patients.
Dahlmann, A. and Dörfelt, K. and Eicher, F. and Linz, P. and Kopp, C. and Mössinger, I. and Horn, S. and Büschges-Seraphin, B. and Wabel, P. and Hammon, M. and Cavallaro, A. and Eckardt, K.U. and Kotanko, P. and Levin, N.W. and Johannes, B. and Uder, M. and Luft, F.C. and Müller, D.N. and Titze, J.M.
Kidney International 87 (2): 434-441. February 2015

Vitamin D depletion aggravates hypertension and target-organ damage.
Andersen, L.B. and Przybyl, L. and Haase, N. and von Versen-Höynck, F. and Qadri, F. and Jørgensen, J.S. and Sorensen, G.L. and Fruekilde, P. and Poglitsch, M. and Szijarto, I. and Gollasch, M. and Peters, J. and Muller, D.N. and Christesen, H.T. and Dechend, R.
Journal of the American Heart Association 4 (2): e001417. February 2015

Skin sodium measured with (23)Na MRI at 7.0 T.
Linz, P. and Santoro, D. and Renz, W. and Rieger, J. and Ruehle, A. and Ruff, J. and Deimling, M. and Rakova, N. and Muller, D.N. and Luft, F.C. and Titze, J. and Niendorf, T.
NMR in Biomedicine 28 (1): 54-62. January 2015

2014

Targeting the ubiquitin-proteasome system in atherosclerosis: status quo, challenges, and perspectives.
Wilck, N. and Ludwig, A.
Antioxidants & Redox Signaling 21 (17): 2344-2363. 24 November 2014

Increase of angiotensin II type 1 receptor auto-antibodies in Huntington's disease.
Lee, D.H. and Heidecke, H. and Schröder, A. and Paul, F. and Wachter, R. and Hoffmann, R. and Ellrichmann, G. and Dragun, D. and Waschbisch, A. and Stegbauer, J. and Klotz, P. and Gold, R. and Dechend, R. and Müller, D.N. and Saft, C. and Linker, R.A.
Molecular Neurodegeneration 9 (1): 49. 15 November 2014

Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling.
Markó, L. and Henke, N. and Park, J.K. and Spallek, B. and Qadri, F. and Balogh, A. and Apel, I.J. and Oravecz-Wilson, K.I. and Choi, M. and Przybyl, L. and Binger, K.J. and Haase, N. and Wilck, N. and Heuser, A. and Fokuhl, V. and Ruland, J. and Lucas, P.C. and McAllister-Lucas, L.M. and Luft, F.C. and Dechend, R. and Müller, D.N.
Hypertension 64 (5): 1032-1039. November 2014

Angiotensin IV is induced in experimental autoimmune encephalomyelitis but fails to influence the disease.
Manzel, A. and Domenig, O. and Ambrosius, B. and Kovacs, A. and Stegbauer, J. and Poglitsch, M. and Mueller, D.N. and Gold, R. and Linker, R.A.
Journal of Neuroimmune Pharmacology 9 (4): 533-543. September 2014

Placental miR-1301 is dysregulated in early-onset preeclampsia and inversely correlated with maternal circulating leptin.
Weedon-Fekjaer, M.S. and Sheng, Y. and Sugulle, M. and Johnsen, G.M. and Herse, F. and Redman, C.W. and Lyle, R. and Dechend, R. and Staff, A.C.
Placenta 35 (9): 709-717. September 2014

Overexpression of CREB protein protects from tunicamycin-induced apoptosis in various rat cell types.
Balogh, A. and Németh, M. and Koloszár, I. and Markó, L. and Przybyl, L. and Jinno, K. and Szigeti, C. and Heffer, M. and Gebhardt, M. and Szeberényi, J. and Müller, D.N. and Sétáló, G. and Pap, M.
Apoptosis 19 (7): 1080-1098. 1 July 2014

Gene expression profiling in PC12 cells infected with an oncolytic Newcastle disease virus strain.
Balogh, A. and Bátor, J. and Markó, L. and Németh, M. and Pap, M. and Sétáló, G. and Müller, D.N. and Csatary, L.K. and Szeberényi, J.
Virus Research 185 : 10-22. 24 June 2014

Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway.
Fischer, R. and Konkel, A. and Mehling, H. and Blossey, K. and Gapelyuk, A. and Wessel, N. and von Schacky, C. and Dechend, R. and Muller, D.N. and Rothe, M. and Luft, F.C. and Weylandt, K. and Schunck, W.H.
Journal of Lipid Research 55 (6): 1150-1164. June 2014

Macrophages in homeostatic immune function.
Jantsch, J. and Binger, K.J. and Müller, D.N. and Titze, J.
Frontiers in Physiology 5 : 146. May 2014

Taking another "look" at sodium.
Titze, J. and Müller, D.N. and Luft, F.C.
Canadian Journal of Cardiology 30 (5): 473-475. May 2014

Relaxin does not improve angiotensin II-induced target-organ damage.
Haase, N. and Rugor, J. and Przybyl, L. and Qadri, F. and Müller, D.N. and Dechend, R.
PLoS ONE 9 (4): e93743. 7 April 2014

Novel ideas about salt, blood pressure, and pregnancy.
Rakova, N. and Muller, D.N. and Staff, A.C. and Luft, F.C. and Dechend, R.
Journal of Reproductive Immunology 101-102 : 135-139. March 2014

Role of "western diet" in inflammatory autoimmune diseases.
Manzel, A. and Muller, D.N. and Hafler, D.A. and Erdman, S.E. and Linker, R.A. and Kleinewietfeld, M.
Current Allergy and Asthma Reports 14 (1): 404. January 2014

2013

Administration of interleukin-17 soluble receptor C suppresses T(H)17 cells, oxidative stress, and hypertension in response to placental ischemia during pregnancy.
Cornelius, D.C. and Hogg, J.P. and Scott, J. and Wallace, K. and Herse, F. and Moseley, J. and Wallukat, G. and Dechend, R. and Lamarca, B.
Hypertension 62 (6): 1068-1073. December 2013

The direct renin inhibitor aliskiren localizes and persists in rat kidneys.
Feldman, D.L. and Jin, L. and Xuan, H. and Persohn, E. and Zhou, W. and Schuetz, H. and Park, J.K. and Mueller, D.N. and Luft, F.C.
American Journal of Physiology Renal Physiology 305 (11): F1593-F1602. December 2013

Amyloid-β peptides activate α1-adrenergic cardiovascular receptors.
Haase, N. and Herse, F. and Spallek, B. and Haase, H. and Morano, I. and Qadri, F. and Szijártó, I.A. and Rohm, I. and Yilmaz, A. and Warrington, J.P. and Ryan, M.J. and Gollasch, M. and Müller, D.N. and Dechend, R. and Wallukat, G.
Hypertension 62 (5): 966-972. November 2013

Endothelin-1, oxidative stress, and endogenous angiotensin II: mechanisms of angiotensin II type I receptor autoantibody-enhanced renal and blood pressure response during pregnancy.
Brewer, J. and Liu, R. and Lu, Y. and Scott, J. and Wallace, K. and Wallukat, G. and Moseley, J. and Herse, F. and Dechend, R. and Martin, J.N. and Lamarca, B.
Hypertension 62 (5): 886-892. November 2013

Autophagy and the (pro)renin receptor.
Binger, K.J. and Muller, D.N.
Frontiers in Endocrinology 4 : 155. 21 October 2013

CYP2J2 overexpression protects against arrhythmia susceptibility in cardiac hypertrophy.
Westphal, C. and Spallek, B. and Konkel, A. and Marko, L. and Qadri, F. and Degraff, L.M. and Schubert, C. and Bradbury, J.A. and Regitz-Zagrosek, V. and Falck, J.R. and Zeldin, D.C. and Müller, D.N. and Schunck, W.H. and Fischer, R.
PLoS ONE 8 (8): e73490. 30 August 2013

The direct renin inhibitor aliskiren improves vascular remodelling in transgenic rats harbouring human renin and angiotensinogen genes.
Savoia, C. and Arrabito, E. and Parente, R. and Sada, L. and Madaro, L. and Nicoletti, C. and Zezza, L. and Alonzo, A. and Rubattu, S. and Michelini, S. and Muller, D.N. and Volpe, M.
Clinical Science 125 (4): 183-189. 1 August 2013

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure.
Wiig, H and Schröder, A and Neuhofer, W and Jantsch, J and Kopp, C and Karlsen, T.V. and Boschmann, M and Goss, J and Bry, M and Rakova, N and Dahlmann, A and Brenner, S and Tenstad, O and Nurmi, H and Mervaala, E and Wagner, H and Beck, FX and Müller, D.N. and Kerjaschki, D and Luft, F.C. and Harrison, D.G. and Alitalo, K and Titze, J
Journal of Clinical Investigation 123 (7): 2803-2815. 1 July 2013

CD4(+) T cells play a critical role in mediating hypertension in response to placental ischemia.
Novotny, S. and Wallace, K. and Herse, F. and Moseley, J. and Darby, M. and Heath, J. and Gill, J. and Wallukat, G. and Martin, J.N. and Dechend, R. and LaMarca, B.
Journal of Hypertension : Open Access 2 : 116. 17 June 2013

Novel signalling mechanisms and targets in renal ischaemia and reperfusion injury.
Kusch, A. and Hoff, U. and Bubalo, G. and Zhu, Y. and Fechner, M. and Schmidt-Ullrich, R. and Marko, L. and Müller, D.N. and Schmidt-Ott, K.M. and Guergen, D. and Blum, M. and Schunck, W.H. and Dragun, D.
Acta Physiologica 208 (1): 25-40. May 2013

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.
Kleinewietfeld, M. and Manzel, A. and Titze, J. and Kvakan, H. and Yosef, N. and Linker, R.A. and Muller, D.N. and Hafler, D.A.
Nature 496 (7446): 518-522. 25 April 2013

Angiotensin II type 1 receptor autoantibody (AT1-AA)-mediated pregnancy hypertension.
Herse, F. and Lamarca, B.
American Journal of Reproductive Immunology 69 (4): 413-418. April 2013

Neutrophil gelatinase-associated lipocalin: pathophysiology and clinical applications.
Singer, E. and Markó, L. and Paragas, N. and Barasch, J. and Dragun, D. and Müller, D.N. and Budde, K. and Schmidt-Ott, K.M.
Acta Physiologica 207 (4): 663-672. April 2013

(23)Na magnetic resonance imaging-determined tissue sodium in healthy subjects and hypertensive patients.
Kopp, C. and Linz, P. and Dahlmann, A. and Hammon, M. and Jantsch, J. and Müller, D.N. and Schmieder, R.E. and Cavallaro, A. and Eckardt, K.U. and Uder, M. and Luft, F.C. and Titze, J.
Hypertension 61 (3): 635-640. March 2013

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways.
Kierdorf, K. and Erny, D. and Goldmann, T. and Sander, V. and Schulz, C. and Perdiguero, E.G. and Wieghofer, P. and Heinrich, A. and Riemke, P. and Hoelscher, C. and Müller, D.N. and Luckow, B. and Brocker, T. and Debowski, K. and Fritz, G. and Opdenakker, G. and Diefenbach, A. and Biber, K. and Heikenwalder, M. and Geissmann, F. and Rosenbauer, F. and Prinz, M.
Nature Neuroscience 16 (3): 273-280. March 2013

Long-term space flight simulation reveals infradian rhythmicity in human Na(+) balance.
Rakova, N. and Jüttner, K. and Dahlmann, A. and Schröder, A. and Linz, P. and Kopp, C. and Rauh, M. and Goller, U. and Beck, L. and Agureev, A. and Vassilieva, G. and Lenkova, L. and Johannes, B. and Wabel, P. and Moissl, U. and Vienken, J. and Gerzer, R. and Eckardt, K.U. and Müller, D.N. and Kirsch, K. and Morukov, B. and Luft, F.C. and Titze, J.
Cell Metabolism 17 (1): 125-131. 8 January 2013

Long-term follow-up of patients with atherosclerotic renal artery disease.
Safak, E. and Wilke, C. and Derer, W. and Busjahn, A. and Gross, M. and Moeckel, M. and Mueller, D.N. and Luft, F.C. and Dechend, R.
Journal of the American Society of Hypertension 7 (1): 24-31. January 2013

2012

Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia.
Herse, F. and LaMarca, B. and Hubel, C.A. and Kaartokallio, T. and Lokki, A.I. and Ekholm, E. and Laivuori, H. and Gauster, M. and Huppertz, B. and Sugulle, M. and Ryan, M.J. and Novotny, S. and Brewer, J. and Park, J.K. and Kacik, M. and Hoyer, J. and Verlohren, S. and Wallukat, G. and Rothe, M. and Luft, F.C. and Muller, D.N. and Schunck, W.H. and Staff, A.C. and Dechend, R.
Circulation 126 (25): 2990-2999. 18 December 2012

Interferon-gamma signaling inhibition ameliorates angiotensin II-induced cardiac damage.
Marko, L. and Kvakan, H. and Park, J.K. and Qadri, F. and Spallek, B. and Binger, K.J. and Bowman, E.P. and Kleinewietfeld, M. and Fokuhl, V. and Dechend, R. and Mueller, D.N.
Hypertension 60 (6): 1430-1436. December 2012

IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy.
Dhillion, P. and Wallace, K. and Herse, F. and Scott, J. and Wallukat, G. and Heath, J. and Mosely, J. and Martin, J.N. and Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 303 (4): R353-R358. 15 August 2012

Immune mechanisms in angiotensin II-induced target-organ damage.
Luft, F.C. and Dechend, R. and Mueller, D.N.
Annals of Medicine 44 (Suppl 1): S49-S54. June 2012

Prorenin receptor regulates more than the renin-angiotensin system.
Mueller, D.N. and Binger, K.J. and Riediger, F.
Annals of Medicine 44 (Suppl 1): S43-S48. June 2012

CD19+CD5+ cells as indicators of preeclampsia.
Jensen, F. and Wallukat, G. and Herse, F. and Budner, O. and El-Mousleh, T. and Costa, S.D. and Dechend, R. and Zenclussen, A.C.
Hypertension 59 (4): 861-868. April 2012

Inhibition of the renin-angiotensin-aldosterone system: is there room for dual blockade in the cardiorenal continuum?
Volpe, M. and Danser, A.H. and Menard, J. and Waeber, B. and Mueller, D.N. and Maggioni, A.P. and Ruilope, L.M.
Journal of Hypertension 30 (4): 647-654. April 2012

Neue Antihypertensiva in Sicht [New antihypertensive drugs].
Derer, W. and Mueller, D.N. and Dechend, R.
In: UNSPECIFIED. 8 March 2012

23Na magnetic resonance imaging of tissue sodium.
Kopp, C. and Linz, P. and Wachsmuth, L. and Dahlmann, A. and Horbach, T. and Schoefl, C. and Renz, W. and Santoro, D. and Niendorf, T. and Mueller, D.N. and Neininger, M. and Cavallaro, A. and Eckardt, K.U. and Schmieder, R.E. and Luft, F.C. and Uder, M. and Titze, J.
Hypertension 59 (1): 167-172. January 2012

Activating autoantibodies against the AT1-receptor in vascular disease.
Dechend, R. and Dragun, D. and Herse, F. and Riemekasten, G. and Schulze-Forster, K. and Mueller, D.N. and Heidecke, H.
Transplantationsmedizin 24 (1): 20-26. 2012

Caloric restriction ameliorates angiotensin II-induced mitochondrial remodeling and cardiac hypertrophy.
Finckenberg, P. and Eriksson, O. and Baumann, M. and Merasto, S. and Lalowski, M.M. and Levijoki, J. and Haasio, K. and Kytoe, V. and Mueller, D.N. and Luft, F.C. and Oresic, M. and Mervaala, E.
Hypertension 59 (1): 76-84. 2012

Effect of cytochrome P450-dependent epoxyeicosanoids on Ristocetin-induced thrombocyte aggregation.
Jung, F. and Schulz, C. and Blaschke, F. and Muller, D.N. and Mrowietz, C. and Franke, R.P. and Lendlein, A. and Schunck, W.H.
Clinical Hemorheology and Microcirculation 52 (2-4): 403-416. 2012

2011

Heparin strongly induces soluble fms-like tyrosine kinase 1 release in vivo and in vitro.
Searle, J. and Mockel, M. and Gwosc, S. and Datwyler, S.A. and Qadri, F. and Albert, G.I. and Holert, F. and Isbruch, A. and Klug, L. and Mueller, D.N. and Dechend, R. and Muller, R. and Vollert, J.O. and Slagman, A. and Mueller, C. and Herse, F.
Arteriosclerosis Thrombosis and Vascular Biology 31 (12): 2972-2974. December 2011

Prorenin receptor is essential for podocyte autophagy and survival.
Riediger, F. and Quack, I. and Qadri, F. and Hartleben, B. and Park, J.K. and Potthoff, S.A. and Sohn, D. and Sihn, G. and Rousselle, A. and Fokuhl, V. and Maschke, U. and Purfuerst, B. and Schneider, W. and Rump, L.C. and Luft, F.C. and Dechend, R. and Bader, M. and Huber, T.B. and Nguyen, G. and Mueller, D.N.
Journal of the American Society of Nephrology 22 (12): 2193-2202. December 2011

Renin- and prorenin-induced effects in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor: does (pro)renin-(pro)renin receptor interaction actually occur?
Batenburg, W.W. and Lu, X. and Leijten, F. and Maschke, U. and Mueller, D.N. and Danser, A.H.J.
Hypertension 58 (6): 1111-1119. December 2011

Spinophilin regulates central angiotensin II-mediated effect on blood pressure.
da Costa Goncalves, A.C. and Fontes, M.A. and Klussmann, E. and Qadri, F. and Janke, J. and Gollasch, M. and Schleifenbaum, J. and Mueller, D. and Jordan, J. and Tank, J. and Luft, F.C. and Gross, V.
Journal of Molecular Medicine 89 (12): 1219-1229. December 2011

Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with Paclitaxel infusion.
Park, J.B. and Kim, B.K. and Kwon, Y.W. and Muller, D.N. and Lee, H.C. and Youn, S.W. and Choi, Y.E. and Lee, S.W. and Yang, H.M. and Cho, H.J. and Park, K.W. and Kim, H.S.
PLoS ONE 6 (11): e28327. 29 November 2011

Stellenwert der fixen Dreierkombination [The role of triple-drug, fixed-dose combinations for the treatment of hypertension].
Derer, W. and Mueller, D.N. and Dechend, R.
In: UNSPECIFIED. 17 November 2011

Adipose tissue-derived soluble fms-like tyrosine kinase 1 is an obesity-relevant endogenous paracrine adipokine.
Herse, F. and Fain, J.N. and Janke, J. and Engeli, S. and Kuhn, C. and Frey, N. and Weich, H.A. and Bergmann, A. and Kappert, K. and Karumanchi, S.A. and Luft, F.C. and Mueller, D.N. and Staff, A.C. and Dechend, R.
Hypertension 58 (1): 37-42. July 2011

Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant rats.
Wenzel, K. and Rajakumar, A. and Haase, H. and Geusens, N. and Hubner, N. and Schulz, H. and Brewer, J. and Roberts, L. and Hubel, C.A. and Herse, F. and Hering, L. and Qadri, F. and Lindschau, C. and Wallukat, G. and Pijnenborg, R. and Heidecke, H. and Riemekasten, G. and Luft, F.C. and Muller, D.N. and Lamarca, B. and Dechend, R.
Hypertension 58 (1): 77-84. July 2011

17(R),18(S)-epoxyeicosatetraenoic acid, a potent eicosapentaenoic acid (EPA) derived regulator of cardiomyocyte contraction: structure-activity relationships and stable analogues.
Falck, J.R. and Wallukat, G. and Puli, N. and Goli, M. and Arnold, C. and Konkel, A. and Rothe, M. and Fischer, R. and Mueller, D.N. and Schunck, W.H.
Journal of Medicinal Chemistry 54 (12): 4109-4118. 23 June 2011

Vitamin D review.
Mueller, D.N. and Kleinewietfeld, M. and Kvakan, H.
Journal of the Renin Angiotensin Aldosterone System 12 (2): 125-128. June 2011

Immune-related effects in hypertension and target-organ damage.
Mueller, D.N. and Kvakan, H. and Luft, F.C.
Current Opinion in Nephrology and Hypertension 20 (2): 113-117. March 2011

Involvement of functional autoantibodies against vascular receptors in systemic sclerosis.
Riemekasten, G. and Philippe, A. and Naether, M. and Slowinski, T. and Mueller, D.N. and Heidecke, H. and Matucci-Cerinic, M. and Czirjak, L. and Lukitsch, I. and Becker, M. and Kill, A. and van Laar, J.M. and Catar, R. and Luft, F.C. and Burmester, G.R. and Hegner, B. and Dragun, D.
Annals of the Rheumatic Diseases 70 (3): 530-536. March 2011

Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury.
Hoff, U. and Lukitsch, I. and Chaykovska, L. and Ladwig, M. and Arnold, C. and Manthati, V.L. and Fuller, T.F. and Schneider, W. and Gollasch, M. and Mueller, D.N. and Flemming, B. and Seeliger, E. and Luft, F.C. and Falck, J.R. and Dragun, D. and Schunck, W.H.
Kidney International 79 (1): 57-65. January 2011

2010

Effects of aliskiren on stroke in rats expressing human renin and angiotensinogen genes.
Schmerbach, K. and Pfab, T. and Zhao, Y. and Culman, J. and Mueller, S. and Villringer, A. and Mueller, D.N. and Hocher, B. and Unger, T. and Thoene-Reineke, C.
PLoS ONE 5 (11): e15052. 29 November 2010

Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of omega-3 fatty acids.
Arnold, C. and Markovic, M. and Blossey, K. and Wallukat, G. and Fischer, R. and Dechend, R. and Konkel, A. and von Schacky, C. and Luft, F.C. and Mueller, D.N. and Rothe, M. and Schunck, W.H.
Journal of Biological Chemistry 285 (43): 32720-32733. 22 October 2010

Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure.
Biala, A. and Martonen, E. and Kaheinen, P. and Levijoki, J. and Finckenberg, P. and Merasto, S. and Louhelainen, M. and Mueller, D.N. and Luft, F.C. and Mervaala, E.
Hypertension Research 33 (10): 1004-1011. October 2010

Effects of circulating and local uteroplacental angiotensin II in rat pregnancy.
Hering, L. and Herse, F. and Geusens, N. and Verlohren, S. and Wenzel, K. and Staff, A.C. and Brosnihan, K.B. and Huppertz, B. and Luft, F.C. and Mueller, D.N. and Pijnenborg, R. and Cartwright, J.E. and Dechend, R.
Hypertension 56 (2): 311-318. August 2010

Inhibition of trophoblast-induced spiral artery remodeling reduces placental perfusion in rat pregnancy.
Verlohren, S. and Geusens, N. and Morton, J. and Verhaegen, I. and Hering, L. and Herse, F. and Dudenhausen, J.W. and Mueller, D.N. and Luft, F.C. and Cartwright, J.E. and Davidge, S.T. and Pijnenborg, R. and Dechend, R.
Hypertension 56 (2): 304-310. August 2010

Response to Blood pressure control: a facelift for macrophages?
Titze, J. and Mueller, D.N. and Luft, F.C.
Hypertension 56 (2): E24. August 2010

Spotlight: Dominik N. Mueller, PhD.
Taylor, J. and Mueller, D.N.
Circulation 121 (24): F139-F141. 22 June 2010

The (pro)renin receptor and the mystic HRP -Is there a role in cardiovascular disease?
Maschke, U. and Mueller, D.N.
Frontiers in Bioscience 2 : 1250-1253. 1 June 2010

Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes.
Biala, A. and Tauriainen, E. and Siltanen, A. and Shi, J. and Merasto, S. and Louhelainen, M. and Martonen, E. and Finckenberg, P. and Mueller, D.N. and Mervaala, E.
Blood Pressure 19 (3): 196-205. June 2010

Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats.
Machnik, A. and Dahlmann, A. and Kopp, C. and Goss, J. and Wagner, H. and van Rooijen, N. and Eckardt, K.U. and Mueller, D.N. and Park, J.K. and Luft, F.C. and Kerjaschki, D. and Titze, J.
Hypertension 55 (3): 755-761. March 2010

alpha(1A)-adrenergic receptor-directed autoimmunity induces left ventricular damage and diastolic dysfunction in rats.
Wenzel, K. and Wallukat, G. and Qadri, F. and Huebner, N. and Schulz, H. and Hummel, O. and Herse, F. and Heuser, A. and Fischer, R. and Heidecke, H. and Luft, F.C. and Mueller, D.N. and Dietz, R. and Dechend, R.
PLoS ONE 5 (2): e9409. 24 February 2010

Aldosteronantagonisten: Welchen Stellenwert haben sie in der antihypertensien Therapie? [Mineralocorticoid receptor antagonists: inhibition of the renin angiotensin system].
Derer, W. and Dechend, R. and Mueller, D.N.
MMW: Fortschritte der Medizin 152 (6): 48-49. 11 February 2010

Increased angiotensin II in the mesometrial triangle of a transgenic rat model of preeclampsia.
Brosnihan, K.B. and Hering, L. and Dechend, R. and Chappell, M.C. and Herse, F.
Hypertension 55 (2): 562-566. February 2010

Metabolomics in angiotensin II-induced cardiac hypertrophy.
Mervaala, E. and Biala, A. and Merasto, S. and Lempiaeinen, J. and Mattila, I. and Martonen, E. and Eriksson, O. and Louhelainen, M. and Finckenberg, P. and Kaheinen, P. and Mueller, D.N. and Luft, F.C. and Lapatto, R. and Oresic, M.
Hypertension 55 (2): 508-515. February 2010

The biology of the (pro)renin receptor.
Nguyen, G. and Mueller, D.N.
Journal of the American Society of Nephrology 21 (1): 18-23. January 2010

Milk products containing bioactive tripeptides have an antihypertensive effect in double transgenic rats (dTGR) harbouring human renin and human angiotensinogen genes.
Jauhiainen, T. and Pilvi, T. and Cheng, Z.J. and Kautiainen, H. and Mueller, D.N. and Vapaatalo, H. and Korpela, R. and Mervaala, E.
Journal of Nutrition and Metabolism 2010 : 287030. 2010

2009

New approaches to pathogenesis and management of hypertension.
Ritz, E. and Krum, H. and Schlaich, M. and Whitbourn, R. and Sobotka, P.A. and Sadowski, J. and Bartus, K. and Kapelak, B. and Walton, A. and Sievert, H. and Thambar, S. and Abraham, W.T. and Esler, M. and Wang, Y. and Tsun, Z. and Machnik, A. and Neuhofer, W. and Jantsch, J. and Dahlmann, A. and Tammela, T. and Machura, K. and Park, J.K. and Beck, F.X. and Mueller, D.N. and Derer, W. and Goss, J. and Ziomber, A. and Dietsch, P. and Wagner, H. and van Rooijen, N. and Kurtz, A. and Hilgers, K.F. and Alitalo, K. and Eckardt, K.U. and Luft, F.C. and Kerjaschki, D. and Titze, J.
Clinical Journal of the American Society of Nephrology 4 (12): 1886-1891. December 2009

Antihypertensive Behandlung. Bei Risikopatienten von Anfang an fix kombinieren [Fixed-dose combinations in antihypertensive treatment: is it necessary to examine the effectiveness of each component?].
Dechend, R. and Derer, W. and Mueller, D.N.
MMW: Fortschritte der Medizin 151 (45): 46-47. 5 November 2009

Role of the immune system in hypertensive target organ damage.
Kvakan, H. and Luft, F.C. and Mueller, D.N.
Trends in Cardiovascular Medicine 19 (7): 242-246. October 2009

Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system.
Stegbauer, J. and Lee, D.H. and Seubert, S. and Ellrichmann, G. and Manzel, A. and Kvakan, H. and Mueller, D.N. and Gaupp, S. and Rump, L.C. and Gold, R. and Linker, R.A.
Proceedings of the National Academy of Sciences of the United States of America 106 (35): 14942-14947. 1 September 2009

Immunology in hypertension, preeclampsia, and target-organ damage.
Verlohren, S. and Mueller, D.N. and Luft, F.C. and Dechend, R.
Hypertension 54 (3): 439-443. September 2009

Growth arrest specific protein 6 participates in DOCA-induced target-organ damage.
Park, J.K. and Theuer, S. and Kirsch, T. and Lindschau, C. and Klinge, U. and Heuser, A. and Plehm, R. and Todiras, M. and Carmeliet, P. and Haller, H. and Luft, F.C. and Mueller, D.N. and Fiebeler, A.
Hypertension 54 (2): 359-364. August 2009

A recently evolved novel trophoblast-enriched secreted form of fms-like tyrosine kinase-1 variant is up-regulated in hypoxia and preeclampsia.
Thomas, C.P. and Andrews, J.I. and Raikwar, N.S. and Kelley, E.A. and Herse, F. and Dechend, R. and Golos, T.G. and Liu, K.Z.
Journal of Clinical Endocrinology and Metabolism 94 (7): 2524-2530. July 2009

Regulatory T cells ameliorate angiotensin II-induced cardiac damage.
Kvakan, H. and Kleinewietfeld, M. and Qadri, F. and Park, J.K. and Fischer, R. and Schwarz, I. and Rahn, H.P. and Plehm, R. and Wellner, M. and Elitok, S. and Gratze, P. and Dechend, R. and Luft, F.C. and Mueller, D.N.
Circulation 119 (22): 2904-2912. 9 June 2009

Circulating and uteroplacental adipocytokine concentrations in preeclampsia.
Herse, F. and Bai, Y. and Staff, A.C. and Jiang, Y.M. and Dechend, R. and Zhou, R.
Reproductive Sciences 16 (6): 584-590. June 2009

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism.
Machnik, A. and Neuhofer, W. and Jantsch, J. and Dahlmann, A. and Tammela, T. and Machura, K. and Park, J.K. and Beck, F.X. and Mueller, D.N. and Derer, W. and Goss, J. and Ziomber, A. and Dietsch, P. and Wagner, H. and van Rooijen, N. and Kurtz, A. and Hilgers, K.F. and Alitalo, K. and Eckardt, K.U. and Luft, F.C. and Kerjaschki, D. and Titze, J.
Nature Medicine 15 (5): 545-552. May 2009

Endogenous angiotensinergic system in neurons of rat and human trigeminal ganglia.
Imboden, H. and Patil, J. and Nussberger, J. and Nicoud, F. and Hess, B. and Ahmed, N. and Schaffner, T. and Wellner, M. and Mueller, D. and Inagami, T. and Senbonmatsu, T. and Pavel, J. and Saavedra, J.M.
Regulatory Peptides 154 (1-3): 23-31. 10 April 2009

Battle against the renin-angiotensin system: help from an unexpected party.
Mueller, D. and Mueller, D.N.
Nephrology Dialysis Transplantation 24 (4): 1110-1112. April 2009

Energy metabolism in human renin-gene transgenic rats. Does renin contribute to obesity?
Gratze, P. and Boschmann, M. and Dechend, R. and Qadri, F. and Malchow, J. and Graeske, S. and Engeli, S. and Janke, J. and Springer, J. and Contrepas, A. and Plehm, R. and Klaus, S. and Nguyen, G. and Luft, F.C. and Mueller, D.N.
Hypertension 53 (3): 516-523. March 2009

Rosuvastatin protects against angiotensin II-induced renal injury in a dose-dependent fashion.
Park, J.K. and Mervaala, E.M. and Mueller, D.N. and Menne, J. and Fiebeler, A. and Luft, F.C. and Haller, H.
Journal of Hypertension 27 (3): 599-605. March 2009

Prevalence of agonistic autoantibodies against the angiotensin II type 1 receptor and soluble fms-like tyrosine kinase 1 in a gestational age-matched case study.
Herse, F. and Verlohren, S. and Wenzel, K. and Pape, J. and Mueller, D.N. and Modrow, S. and Wallukat, G. and Luft, F.C. and Redman, C.W. and Dechend, R.
Hypertension 53 (2): 393-398. February 2009

2008

Complement activation in vascular remodeling and organ damage.
Shagdarsuren, E. and Mueller, D.N. and Weber, C. and Zernecke, A.
Drug Discovery Today: Disease Mechanisms 5 (3-4): e299-e306. December 2008

Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertension.
Wenzel, K. and Haase, H. and Wallukat, G. and Derer, W. and Bartel, S. and Homuth, V. and Herse, F. and Huebner, N. and Schulz, H. and Janczikowski, M. and Lindschau, C. and Schroeder, C. and Verlohren, S. and Morano, I. and Mueller, D.N. and Luft, F.C. and Dietz, R. and Dechend, R. and Karczewski, P.
PLoS ONE 3 (11): e3742. 17 November 2008

Renin receptor blockade: a better strategy for renal protection than Renin-Angiotensin system inhibition?
Mueller, D.N. and Luft, F.C.
Current Hypertension Reports 10 (5): 405-409. October 2008

Effect of (pro)renin receptor inhibition by a decoy peptide on renal damage in the clipped kidney of Goldblatt rats.
Krebs, C. and Weber, M. and Steinmetz, O. and Meyer-Schwesinger, C. and Stahl, R. and Danser, A.H. and Garrelds, I. and van Goor, H. and Nguyen, G. and Mueller, D.N. and Wenzel, U.
Kidney International 74 (6): 823-824. 2 September 2008

Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mREN-2)27 rats.
Feldman, D.L. and Jin, L. and Xuan, H. and Contrepas, A. and Zhou, Y. and Webb, R.L. and Mueller, D.N. and Feldt, S. and Cumin, F. and Maniara, W. and Persohn, E. and Schuetz, H. and Jan Danser, A.H. and Nguyen, G.
Hypertension 52 (1): 130-136. July 2008

AT1-receptor autoantibodies and uteroplacental RAS in pregnancy and pre-eclampsia.
Herse, F. and Staff, A.C. and Hering, L. and Mueller, D.N. and Luft, F.C. and Dechend, R.
Journal of Molecular Medicine 86 (6): 697-703. June 2008

Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells.
Batenburg, W.W. and de Bruin, R.J. and van Gool, J.M. and Mueller, D.N. and Bader, M. and Nguyen, G. and Danser, A.H.
Arteriosclerosis Thrombosis and Vascular Biology 28 (6): 1151-1157. June 2008

Aliskiren-mode of action and preclinical data.
Mueller, D.N. and Derer, W. and Dechend, R.
Journal of Molecular Medicine 86 (6): 659-662. June 2008

Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension.
Gratze, P. and Dechend, R. and Stocker, C. and Park, J.K. and Feldt, S. and Shagdarsuren, E. and Wellner, M. and Gueler, F. and Rong, S. and Gross, V. and Obst, M. and Plehm, R. and Alenina, N. and Zenclussen, A. and Titze, J. and Small, K. and Yokota, Y. and Zenke, M. and Luft, F.C. and Mueller, D.N.
Circulation 117 (20): 2645-2656. 20 May 2008

Glucocorticoid-related signaling effects in vascular smooth muscle cells.
Molnar, G.A. and Lindschau, C. and Dubrovska, G. and Mertens, P.R. and Kirsch, T. and Quinkler, M. and Gollasch, M. and Wresche, S. and Luft, F.C. and Mueller, D.N. and Fiebeler, A.
Hypertension 51 (5): 1372-1378. May 2008

The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling.
Feldt, S. and Maschke, U. and Dechend, R. and Luft, F.C. and Mueller, D.N.
Journal of the American Society of Nephrology 19 (4): 743-748. April 2008

(Pro)renin receptor peptide inhibitor "handle-region" peptide does not affect hypertensive nephrosclerosis in goldblatt rats.
Mueller, D.N. and Klanke, B. and Feldt, S. and Cordasic, N. and Hartner, A. and Schmieder, R.E. and Luft, F.C. and Hilgers, K.F.
Hypertension 51 (3): 676-681. March 2008

Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide.
Feldt, S. and Batenburg, W.W. and Mazak, I. and Maschke, U. and Wellner, M. and Kvakan, H. and Dechend, R. and Fiebeler, A. and Burckle, C. and Contrepas, A. and Danser, A.H. and Bader, M. and Nguyen, G. and Luft, F.C. and Mueller, D.N.
Hypertension 51 (3): 682-688. March 2008

Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension.
Fischer, R. and Dechend, R. and Qadri, F. and Markovic, M. and Feldt, S. and Herse, F. and Park, J.K. and Gapelyuk, A. and Schwarz, I. and Zacharzowsky, U.B. and Plehm, R. and Safak, E. and Heuser, A. and Schirdewan, A. and Luft, F.C. and Schunck, W.H. and Mueller, D.N.
Hypertension 51 (2): 540-546. February 2008

Trophoblasts reduce the vascular smooth muscle cell proatherogenic response.
Hering, L. and Herse, F. and Verlohren, S. and Park, J.K. and Wellner, M. and Qadri, F. and Pijnenborg, R. and Staff, A.C. and Huppertz, B. and Mueller, D.N. and Luft, F.C. and Dechend, R.
Hypertension 51 (2): 554-559. February 2008

Uterine vascular function in a transgenic preeclampsia rat model.
Verlohren, S. and Niehoff, M. and Hering, L. and Geusens, N. and Herse, F. and Tintu, A.N. and Plagemann, A. and Le Noble, F. and Pijnenborg, R. and Mueller, D.N. and Luft, F.C. and Dudenhausen, J.W. and Gollasch, M. and Dechend, R.
Hypertension 51 (2): 547-553. February 2008

Agonistic antibodies directed at cell surface receptors and cardiovascular disease.
Luft, F.C. and Dechend, R. and Dragun, D. and Mueller, D.N. and Wallukat, G.
Journal of the American Society of Hypertension 2 (1): 8-14. January 2008

2007

Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor.
Batenburg, W.W. and Krop, M. and Garrelds, I.M. and de Vries, R. and de Bruin, R.J.A. and Burckle, C.A. and Mueller, D.N. and Bader, M. and Nguyen, G. and Danser, A.H.J.
Journal of Hypertension 25 (12): 2441-2453. December 2007

Die direkte Renin-Inhibition - ein neuer Ansatz in der therapeutischen Blockade des Renin-Angiotensin-Systems [Direct renin inhibition - a new approach in the therapeutic blockade of the renin-angiotensin system].
Derer, W. and Mueller, D.N.
Nieren- und Hochdruckkrankheiten 36 (11): 549-550. November 2007

Spotlight on renin. Mechanisms of hypertension-induced target organ damage.
Mueller, D.N.
Journal of the Renin Angiotensin Aldosterone System 8 (3): 148-150. September 2007

Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage.
Henke, N. and Schmidt-Ullrich, R. and Dechend, R. and Park, J.K. and Qadri, F. and Wellner, M. and Obst, M. and Gross, V. and Dietz, R. and Luft, F.C. and Scheidereit, C. and Mueller, D.N.
Circulation Research 101 (3): 268-276. 3 August 2007

Angiotensin II-induced sudden arrhythmic death and electrical remodeling.
Fischer, R. and Dechend, R. and Gapelyuk, A. and Shagdarsuren, E. and Gruner, K. and Gruner, A. and Gratze, P. and Qadri, F. and Wellner, M. and Fiebeler, A. and Dietz, R. and Luft, F.C. and Mueller, D.N. and Schirdewan, A.
American Journal of Physiology Heart and Circulatory Physiology 293 (2): H1242-H1253. 1 August 2007

Murine pre-eclampsia induced by unspecific activation of the immune system correlates with alterations in the eNOS and AT1 receptor expression in the kidneys and placenta.
Schmid, M. and Sollwedel, A. and Thuere, C. and Wafula, P.O. and Zenclussen, M.L. and Mueller, D.N. and Gratze, P. and Woiciechowsky, C. and Volk, H.D. and Zenclussen, A.C.
Placenta 28 (7): 688-700. August 2007

Low-dose renin inhibitor and low-dose AT(1)-receptor blocker therapy ameliorate target-organ damage in rats harbouring human renin and angiotensinogen genes.
Dechend, R. and Shagdarsuren, E. and Gratze, P. and Fiebeler, A. and Pilz, B. and Meiners, S. and Derer, W. and Feldman, D.L. and Webb, R. and Mueller, D.N.
Journal of the Renin Angiotensin Aldosterone System 8 (2): 81-84. June 2007

Time course of changes in cardiac magnetic field mapping after myocardial infarction in rats.
Fischer, R. and Gapelyuk, A. and Wessel, N. and Gruner, K. and Gruner, A. and Mueller, D. and Dietz, R. and Schirdewan, A.
International Congress Series 1300 (1300): 484-487. June 2007

Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.
Mueller, D.N. and Schmidt, C. and Barbosa-Sicard, E. and Wellner, M. and Gross, V. and Hercule, H. and Markovic, M. and Honeck, H. and Luft, F.C. and Schunck, W.H.
Biochemical Journal 403 (1): 109-118. April 2007

Aldosterone, mineralocorticoid receptors, and vascular inflammation.
Fiebeler, A. and Mueller, D.N. and Shagdarsuren, E. and Luft, F.C.
Current Opinion in Nephrology and Hypertension 16 (2): 134-142. March 2007

Dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia.
Herse, F. and Dechend, R. and Harsem, N.K. and Wallukat, G. and Janke, J. and Qadri, F. and Hering, L. and Mueller, D.N. and Luft, F.C. and Staff, A.C.
Hypertension 49 (3): 604-611. March 2007

p38 mitogen-activated protein kinase inhibition ameliorates angiotensin II-induced target organ damage.
Park, J.K. and Fischer, R. and Dechend, R. and Shagdarsuren, E. and Gapeljuk, A. and Wellner, M. and Meiners, S. and Gratze, P. and Al-Saadi, N. and Feldt, S. and Fiebeler, A. and Madwed, J.B. and Schirdewan, A. and Haller, H. and Luft, F.C. and Mueller, D.N.
Hypertension 49 (3): 481-489. March 2007

2006

Direct renin inhibition with aliskiren in hypertension and target organ damage.
Mueller, D.N. and Luft, F.C.
Clinical Journal of the American Society of Nephrology 1 (2): 221-228. March 2006

Elevated blood pressure and heart rate in human renin receptor transgenic rats.
Burckle, C.A. and Danser, A.H.J. and Mueller, D.N. and Garrelds, I.M. and Gasc, J.M. and Popova, E. and Plehm, R. and Peters, J. and Bader, M. and Nguyen, G.
Hypertension 47 (3): 552-556. March 2006

Agonistic antibodies directed at the angiotensin II, AT1 receptor in preeclampsia.
Dechend, R. and Homuth, V. and Wallukat, G. and Mueller, D.N. and Krause, M. and Dudenhausen, J. and Haller, H. and Luft, F.C.
Journal of the Society for Gynecologic Investigation 13 : 79-86. February 2006

2005

Complement activation in angiotensin II-induced organ damage.
Shagdarsuren, E. and Wellner, M. and Braesen, J.H. and Park, J.K. and Fiebeler, A. and Henke, N. and Dechend, R. and Gratze, P. and Luft, F.C. and Mueller, D.N.
Circulation Research 97 (7): 716-724. 18 August 2005

Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats.
Pilz, B. and Shagdarsuren, E. and Wellner, M. and Fiebeler, A. and Dechend, R. and Gratze, P. and Meiners, S. and Feldman, D.L. and Webb, R.L. and Garrelds, I.M. and Danser, A.H.J. and Luft, F.C. and Mueller, D.N.
Hypertension 46 (3): 569-576. 15 August 2005

Eicosapentaenoic acid metabolism by cytochrome P450 enzymes of the CYP2C subfamily.
Barbosa-Sicard, E. and Markovic, M. and Honeck, H. and Christ, B. and Muller, D.N. and Schunck, W.H.
Biochemical and Biophysical Research Communications 329 (4): 1275-1281. 22 April 2005

Activating auto-antibodies against the AT1 receptor in preeclampsia.
Dechend, R. and Mueller, D.N. and Wallukat, G. and Homuth, V. and Krause, M. and Dudenhausen, J. and Luft, F.C.
Autoimmunity Reviews 4 (1): 61-65. 1 January 2005

Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia.
Dechend, R. and Gratze, P. and Wallukat, G. and Shagdarsuren, E. and Plehm, R. and Braesen, J.H. and Fiebeler, A. and Schneider, W. and Caluwaerts, S. and Vercruysse, L. and Pijnenborg, R. and Luft, F.C. and Mueller, D.N.
Hypertension 45 (4): 742-746. 1 January 2005

Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage.
Fiebeler, A. and Nussberger, J. and Shagdarsuren, E. and Rong, S. and Hilfenhaus, G. and Al-Saadi, N. and Dechend, R. and Wellner, M. and Meiners, S. and Maser-Gluth, C. and Jeng, A.Y. and Webb, R.L. and Luft, F.C. and Mueller, D.N.
Circulation 111 (23): 3087-3094. 1 January 2005

Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection (authors reply inN Engl J Med. 2005 May 12;352(19):2027-8).
Dragun, D. and Mueller, D.N. and Braesen, J.H. and Fritsche, L. and Nieminen-Kelhae, M. and Dechend, R. and Kintscher, U. and Rudolph, B. and Hoebeke, J. and Eckert, D. and Mazak, I. and Plehm, R. and Schoenemann, C. and Unger, T. and Budde, K. and Neumayer, H.H. and Luft, F.C. and Wallukat, G.
New England Journal of Medicine 352 (6): 558-569. 1 January 2005

Cardiac gene expression profile in rats with terminal heart failure and cachexia.
Wellner, M. and Dechend, R. and Park, J.K. and Shagdasuren, E. and Al-Saadi, N. and Kirsch, T. and Gratze, P. and Schneider, W. and Meiners, S. and Fiebeler, A. and Haller, H. and Luft, F.C. and Mueller, D.N.
Physiological Genomics 20 : 256-267. 1 January 2005

Inducible NOS inhibition, eicosapentaenoic acid supplementation, and angiotensin II-induced renal damage.
Theuer, J. and Shagdarsuren, E. and Muller, D.N. and Kaergel, E. and Honeck, H. and Park, J.K. and Fiebeler, A. and Dechend, R. and Haller, H. and Luft, F.C. and Schunck, W.H.
Kidney International 67 : 248-258. 1 January 2005

Magnesium supplementation prevents angiotensin II-induced myocardial damage and CTGF overexpression.
Finckenberg, P. and Merasto, S. and Louhelainen, M. and Lindgren, L. and Vapaatalo, H. and Mueller, D.N. and Luft, F.C. and Mervaala, E.M.
Journal of Hypertension 23 : 375-380. 1 January 2005

2004

AT1 receptor agonistic antibodies, hypertension, and preeclampsia.
Dechend, R. and Mueller, D.N. and Wallukat, G. and Homuth, V. and Krause, M. and Dudenhausen, J. and Luft, F.C.
Seminars in Nephrology 24 : 571-579. 1 December 2004

Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells.
Mazak, I. and Fiebeler, A. and Muller, D.N. and Park, J.K. and Shagdarsuren, E. and Lindschau, C. and Dechend, R. and Viedt, C. and Pilz, B. and Haller, H. and Luft, F.C.
Circulation 109 (22): 2792-2800. 8 June 2004

Nitric oxide synthase expression in AT receptor-deficient mice after DOCA-salt.
Obst, M. and Gross, V. and Bonartsev, A. and Janke, J. and Mueller, D.N. and Park, J.K. and Kaergel, E. and Luft, F.C.
Kidney International 65 (6): 2268-2278. June 2004

Cardiac hypertrophy and fibrosis in chronic L-NAME-treated AT2 receptor-deficient mice.
Gross, V. and Obst, M. and Kiss, E. and Janke, J. and Mazak, I. and Shagdarsuren, E. and Mueller, D.N. and Langenickel, T.H. and Groene, H.J. and Luft, F.C.
Journal of Hypertension 22 (5): 997-1005. May 2004

A peroxisome proliferator-activated receptor-alpha activator induces renal CYP2C23 activity and protects from angiotensin II-induced renal injury.
Muller, D.N. and Theuer, J. and Shagdarsuren, E. and Kaergel, E. and Honeck, H. and Park, J.K. and Markovic, M. and Barbosa-Sicard, E. and Dechend, R. and Wellner, M. and Kirsch, T. and Fiebeler, A. and Rothe, M. and Haller, H. and Luft, F.C. and Schunck, W.H.
American Journal of Pathology 164 (2): 521-532. 1 January 2004

Growth arrest specific protein 6/Axl signaling in human inflammatory renal diseases.
Fiebeler, A. and Park, J.K. and Muller, D.N. and Lindschau, C. and Mengel, M. and Merkel, S. and Banas, B. and Luft, F.C. and Haller, H.
American Journal of Kidney Diseases 43 (2): 286-295. 1 January 2004

2003

Lipoic acid supplementation prevents angiotensin II-induced renal injury.
Mervaala, E. and Finckenberg, P. and Lapatto, R. and Mueller, D.N. and Park, J.K. and Dechend, R. and Ganten, D. and Vapaatalo, H. and Luft, F.C.
Kidney International 64 (2): 501-508. August 2003

Angiotensin II and endothelin induce inflammation and thereby promote hypertension-induced end-organ damage.
Mueller, D.N. and Fiebeler, A. and Park, J.K. and Dechend, R. and Luft, F.C.
Clinical Nephrology 60 (Suppl.1): S2-S12. July 2003

Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways.
Finckenberg, P. and Inkinen, K. and Ahonen, J. and Merasto, S. and Louhelainen, M. and Vapaatalo, H. and Mueller, D. and Ganten, D. and Luft, F.C. and Mervaala, E.
American Journal of Pathology 163 (1): 355-366. July 2003

AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase.
Dechend, R. and Viedt, C. and Mueller, D.N. and Ugele, B. and Brandes, R.P. and Wallukat, G. and Park, J.K. and Janke, J. and Barta, P. and Theuer, J. and Fiebeler, A. and Homuth, V. and Dietz, R. and Haller, H. and Kreuzer, J. and Luft, F.C.
Circulation 107 (12): 1632-1639. 1 April 2003

Entacapone protects from angiotensin II-induced inflammation and renal injury.
Helkamaa, T. and Finckenberg, P. and Louhelainen, M. and Merasto, S. and Rauhala, P. and Lapatto, R. and Cheng, Z.J. and Reenilae, I. and Maennistoe, P. and Mueller, D.N. and Luft, F.C. and Mervaala, E.M.
Journal of Hypertension 21 : 2353-2363. 1 January 2003

2002

Endothelin-converting enzyme inhibition ameliorates angiotensin II-induced cardiac damage.
Muller, D.N. and Mullally, A. and Dechend, R. and Park, J.K. and Fiebeler, A. and Pilz, B. and Loeffler, B.M. and Blum-Kaelin, D. and Masur, S. and Dehmlow, H. and Aebi, J.D. and Haller, H. and Luft, F.C.
Hypertension 40 (6): 840-846. December 2002

Immunosuppressive treatment protects against angiotensin II-induced renal damage.
Muller, D.N. and Shagdarsuren, E. and Park, J.K. and Dechend, R. and Mervaala, E. and Hampich, F. and Fiebeler, A. and Ju, X. and Finckenberg, P. and Theuer, J. and Viedt, C. and Kreuzer, J. and Heidecke, H. and Haller, H. and Zenke, M. and Luft, F.C.
American Journal of Pathology 161 (5): 1679-1693. November 2002

P450-dependent arachidonic acid metabolism and angiotensin II-induced renal damage.
Kaergel, E. and Mueller, D.N. and Honeck, H. and Theuer, J. and Shagdarsuren, E. and Mullally, A. and Luft, F.C. and Schunck, W.H.
Hypertension 40 (3): 273-279. 1 September 2002

Postischemic acute renal failure is reduced by short-term statin treatment in a rat model.
Gueler, F. and Rong, S. and Park, J.K. and Fiebeler, A. and Menne, J. and Elger, M. and Mueller, D.N. and Hampich, F. and Dechend, R. and Kunter, U. and Luft, F.C. and Haller, H.
Journal of the American Society of Nephrology 13 (9): 2288-2298. 1 September 2002

Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats.
Theuer, J. and Dechend, R. and Muller, D.N. and Park, J.K. and Fiebeler, A. and Barta, P. and Ganten, D. and Haller, H. and Dietz, R. and Luft, F.C.
BMC Cardiovascular Disorders 2 : 3. 18 January 2002

A gene expression analysis in rat kidney following high and low salt intake.
Barta, P. and Monti, J. and Maass, P.G. and Gorzelniak, K. and Mueller, D.N. and Dechend, R. and Luft, F.C. and Huebner, N. and Sharma, A.M.
Journal of Hypertension 20 : 1115-1120. 1 January 2002

Lacidipine inhibits adhesion molecule and oxidase expression independent of blood pressure reduction in angiotensin-induced vascular injury.
Park, J.K. and Fiebeler, A. and Muller, D.N. and Mervaala, E.M.A. and Dechend, R. and Abou-Rebyeh, F. and Luft, F.C. and Haller, H.
Hypertension 39 : 685-689. 1 January 2002

2001

Renin uptake by the endothelium mediates vascular angiotensin formation.
Hilgers, K.F. and Veelken, R. and Mueller, D.N. and Kohler, H. and Hartner, A. and Botkin, S.R. and Stumpf, C. and Schmieder, R.E. and Gomez, R.A.
Hypertension 38 : 243-248. August 2001

Angiotensin-induced inflammation and vascular injury.
Mueller, D.N. and Dechend, R. and Fiebeler, A. and Park, J.K. and Haller, H. and Luft, F.C.
Contributions to Nephrology 135 : 138-152. April 2001

Piperidine renin inhibitors: from leads to drug candidates.
Maerki, H.P. and Binggeli, A. and Bittner, B. and Bohner-Lang, V. and Breu, V. and Bur, D. and Coassolo, P.H. and Clozel, J.P. and D'Arcy, A. and Doebeli, H. and Fischli, W. and Funk, C.H. and Foricher, J. and Giller, T. and Grueninger, F. and Guenzi, A. and Gueller, R. and Hartung, T. and Hirth, G. and Jenny, C.H. and Kansy, M. and Klinkhammer, U. and Lave, T. and Lohri, B. and Luft, F.C. and Mervaala, E.M. and Mueller, D.N. and Mueller, M. and Montavon, F. and Oefner, C.H. and Qiu, C. and Reichel, A. and Sanwald-Ducray, P. and Scalone, M. and Schleimer, M. and Schmid, R. and Treiber, H. and Treiber, A. and Valdenaire, O. and Vieira, E. and Waldmeier, P. and Wiegand-Chou, R. and Wilhelm, M. and Wostl, W. and Zell, M. and Zell, R.
Farmaco 56 (1-2): 21-27. 1 March 2001

Amelioration of angiotensin II-induced cardiac injury by a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
Dechend, R. and Fiebeler, A. and Park, J.K. and Muller, D.N. and Theuer, J. and Mervaala, E. and Bieringer, M. and Gulba, D. and Dietz, R. and Luft, F.C. and Haller, H.
Circulation 104 : 576-581. 1 January 2001

Aspirin inhibits NF-kappa B and protects from angiotensin II-induced organ damage.
Mueller, D.N. and Heissmeyer, V. and Dechend, R. and Hampich, F. and Park, J.K. and Fiebeler, A. and Shagdarsuren, E. and Theuer, J. and Elger, M. and Pilz, B. and Breu, V. and Schroer, K. and Ganten, D. and Dietz, R. and Haller, H. and Scheidereit, C. and Luft, F.C.
FASEB Journal 15 : 1822-1824. 1 January 2001

Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes.
Mervaala, E.M.A. and Cheng, Z.J. and Tikkanen, I. and Lapatto, R. and Nurminen, K. and Vapaatalo, H. and Mueller, D.N. and Fiebeler, A. and Ganten, U. and Ganten, D. and Luft, F.C.
Hypertension 37 (2): 414-418. 1 January 2001

Mineralocorticoid receptor affects AP-1 and nuclear factor-kappa B activation in angiotensin II-induced cardiac injury.
Fiebeler, A. and Schmidt, F. and Mueller, D.N. and Park, J.K. and Dechend, R. and Bieringer, M. and Shagdarsuren, E. and Breu, V. and Haller, H. and Luft, F.C.
Hypertension 37 : 787-793. 1 January 2001

Modulating angiotensin II-induced inflammation by HMG Co-A reductase inhibition.
Dechend, R. and Fiebler, A. and Lindschau, C. and Bischoff, H. and Mueller, D.N. and Park, J.K. and Dietz, R. and Haller, H. and Luft, F.C.
American Journal of Hypertension 14 : 55S-61S. 1 January 2001

Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research.
Bader, M. and Peters, J. and Baltatu, O. and Mueller, D.N. and Luft, F.C. and Ganten, D.
Journal of Molecular Medicine 79 (2): 76-102. 1 January 2001

Angiotensin-induced inflammation and novel approaches to treatment.
Mueller, D.N. and Dechend, R. and Fiebeler, A. and Park, J.K. and Haller, H. and Luft, F.C.
Advances in Nephrology from the Necker Hospital 31 : 89-103. 2001

2000

Cerivastatin prevents angiotensin II-induced renal injury independent of blood pressure- and cholesterol-lowering effects.
Park, J.K. and Mueller, D.N. and Mervaala, E.M.A. and Dechend, R. and Fiebeler, A. and Schmidt, F. and Bieringer, M. and Schaefer, O. and Lindschau, C. and Schneider, W. and Ganten, D. and Luft, F.C. and Haller, H.
Kidney International 58 (4): 1420-1430. 1 October 2000

Effect of Bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage.
Muller, D.N. and Mervaala, E.M.A. and Schmidt, F. and Park, J.K. and Dechend, R. and Genersch, E. and Breu, V. and Loeffler, B.M. and Ganten, D. and Schneider, W. and Haller, H. and Luft, F.C.
Hypertension 36 (2): 282-290. 1 August 2000

Angiotensin II (AT1) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy.
Mueller, D.N. and Mervaala, E.M.A. and Dechend, R. and Fiebeler, A. and Park, J.K. and Schmidt, F. and Theuer, J. and Breu, V. and Mackman, N. and Luther, T. and Schneider, W. and Gulba, D. and Ganten, D. and Haller, H. and Luft, F.C.
American Journal of Pathology 157 : 111-122. 1 July 2000

Blood pressure-independent effects in rats with human renin and angiotensinogen genes.
Mervaala, E. and Mueller, D.N. and Schmidt, F. and Park, J.K. and Gross, V. and Bader, M. and Breu, V. and Ganten, D. and Haller, H. and Luft, F.C.
Hypertension 35 (2): 587-594. 1 February 2000

Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes.
Mervaala, E. and Mueller, D.N. and Park, J.K. and Dechend, R. and Schmidt, F. and Fiebeler, A. and Bieringer, M. and Breu, V. and Ganten, D. and Haller, H. and Luft, F.C.
Hypertension 35 (1): 360-366. 1 January 2000

NF-kappaB Inhibition Ameliorates Angiotensin II-Induced Inflammatory Damage in Rats.
Muller, D.N. and Dechend, R. and Mervaala, E.M.A. and Park, J.K. and Schmidt, F. and Fiebeler, A. and Theuer, J. and Breu, V. and Ganten, D. and Haller, H. and Luft, F.C.
Hypertension 35 (1): 193-201. 1 January 2000

1999

Effects of human prorenin in rats transgenic for human angiotensinogen.
Mueller, D.N. and Hilgers, K.F. and Mathews, S. and Breu, V. and Fischli, W. and Uhlmann, R. and Luft, F.C.
Hypertension 33 : 312-317. 1 January 1999

Hypertension-induced end-organ damage - A new transgenic approach to an old problem.
Luft, F.C. and Mervaala, E. and Mueller, D.N. and Gross, V. and Schmidt, F. and Park, J.K. and Schmitz, C. and Lippoldt, A. and Breu, V. and Dechend, R. and Dragun, D. and Schneider, W. and Ganten, D. and Haller, H.
Hypertension 33 : 212-218. 1 January 1999

Monocyte infiltration and adhesion molecules in a rat model of high human renin hypertension.
Mervaala, E.M.A. and Mueller, D.N. and Park, J.K. and Schmidt, F. and Loehn, M. and Breu, V. and Dragun, D. and Ganten, D. and Haller, H. and Luft, F.C.
Hypertension 33 : 389-395. 1 January 1999

1998

Local angiotensin II generation in the rat heart: role of renin uptake.
Mueller, D.N. and Fischli, W. and Clozel, J.P. and Hilgers, K.F. and Bohlender, J. and Menard, J. and Busjahn, A. and Ganten, D. and Luft, F.C.
Circulation Research 82 (1): 13-20. 9 January 1998

Angiotensinases restrict locally generated angiotensin II to the blood vessel wall.
Hilgers, K.F. and Bingener, E. and Stumpf, C. and Muller, D.N. and Schmieder, R.E. and Veelken, R.
Hypertension 31 : 368-372. 1 January 1998

The renin-angiotensin system in the vessel wall.
Mueller, D.N. and Luft, F.C.
Basic Research in Cardiology 93 (Suppl 2): 7-14. 1 January 1998

1997

Vascular angiotensin converting enzyme expression regulates local angiotensin II.
Mueller, D.N. and Bohlender, J. and Hilgers, K.F. and Dragun, D. and Costerousse, O. and Menard, J. and Luft, F.C.
Hypertension 29 (1 Pt 1): 98-104. 1 January 1997

1995

Effects of human renin in the vasculature of rats transgenic for human angiotensinogen.
Mueller, D.N. and Hilgers, K.F. and Bohlender, J. and Lippoldt, A. and Wagner, J. and Fischli, W. and Ganten, D. and Mann, J.F.E. and Luft, F.C.
Hypertension 26 : 272-278. 1 January 1995

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