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Mapping the human genetic architecture of COVID-19.

Nature 600 (7889): 472-477. December 2021

COVID-19 highlights the model dilemma in biomedical research.
Adhikary, P.P. and Ul Ain, Q. and Hocke, A.C. and Hedtrich, S.
Nature Reviews Materials 6 (5): 374-376. 2021

A role for STOML3 in olfactory sensory transduction.
Agostinelli, E. and Gonzalez-Velandia, K.Y. and Hernandez-Clavijo, A. and Maurya, D.K. and Xerxa, E. and Lewin, G.R. and Dibattista, M. and Menini, A. and Pifferi, S.
eNeuro 8 (2): ENEURO.0565-20.2021. 26 March 2021

Serum glial fibrillary acidic protein: a neuromyelitis optica spectrum disorder biomarker.
Aktas, O. and Smith, M.A. and Rees, W.A. and Bennett, J.L. and She, D. and Katz, E. and Cree, B.A.C.
Annals of Neurology 89 (5): 895-910. May 2021

Measuring myocardial extracellular volume of the right ventricle in patients with congenital heart disease.
Al-Wakeel-Marquard, N. and Ferreira da Silva, T. and Jeuthe, S. and Rastin, S. and Muench, F. and O H-Ici, D. and Yilmaz, S. and Berger, F. and Kuehne, T. and Messroghli, D.R.
Scientific Reports 11 (1): 2679. 29 January 2021

Diffuse myocardial fibrosis by T1 mapping is associated with heart failure in pediatric primary dilated cardiomyopathy.
Al-Wakeel-Marquard, N. and Seidel, F. and Herbst, C. and Kühnisch, J. and Kuehne, T. and Berger, F. and Klaassen, S. and Messroghli, D.R.
International Journal of Cardiology 333 : 219-225. 15 June 2021

Angiotensin 1-7 prevents the excessive force loss resulting from 14- and 28-day denervation in mouse EDL and soleus muscle.
Albadrani, H. and Ammar, T. and Bader, M. and Renaud, J.M.
Journal of General Physiology 153 (12): e201912556. 6 December 2021

From operating table to laboratory bench: the path toward metastasis research from the clinical setting.
Alberto Vilchez, M. and Rau, B.
Methods in Molecular Biology 2294 : 325-333. 2021

Spontaneous non-sustained ventricular tachycardia and premature ventricular contractions and their prognostic relevance in patients with cancer in routine care.
Albrecht, A. and Porthun, J. and Eucker, J. and Coats, A.J.S. and von Haehling, S. and Pezzutto, A. and Karakas, M. and Riess, H. and Keller, U. and Landmesser, U. and Haverkamp, W. and Anker, S.D. and Anker, M.S.
Cancers 13 (10): 2303. 12 May 2021

Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington's disease mice.
Alcalá-Vida, R. and Seguin, J. and Lotz, C. and Molitor, A.M. and Irastorza-Azcarate, I. and Awada, A. and Karasu, N. and Bombardier, A. and Cosquer, B. and Skarmeta, J.L.G. and Cassel, J.C. and Boutillier, A.L. and Sexton, T. and Merienne, K.
Nature Communications 12 (1): 364. 13 January 2021

Identification of the gliogenic state of human neural stem cells to optimize in vitro astrocyte differentiation.
Alisch, M. and Kerkering, J. and Crowley, T. and Rosiewicz, K. and Paul, F. and Siffrin, V.
Journal of Neuroscience Methods 361 : 109284. 1 September 2021

Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator.
Allou, L. and Balzano, S. and Magg, A. and Quinodoz, M. and Royer-Bertrand, B. and Schöpflin, R. and Chan, W.L. and Speck-Martins, C.E. and Carvalho, D.R. and Farage, L. and Lourenço, C.M. and Albuquerque, R. and Rajagopal, S. and Nampoothiri, S. and Campos-Xavier, B. and Chiesa, C. and Niel-Bütschi, F. and Wittler, L. and Timmermann, B. and Spielmann, M. and Robson, M.I. and Ringel, A. and Heinrich, V. and Cova, G. and Andrey, G. and Prada-Medina, C.A. and Pescini-Gobert, R. and Unger, S. and Bonafé, L. and Grote, P. and Rivolta, C. and Mundlos, S. and Superti-Furga, A.
Nature 592 (7852): 93-98. 1 April 2021

A novel investigation method for axonal damage in neuromyelitis optica spectrum disorder: In vivo corneal confocal microscopy.
Altıntaş, A. and Yildiz-Tas, A. and Yilmaz, S. and Bayraktutar, B.N. and Comert, M.C. and Zimmermann, H. and Brandt, A.U. and Paul, F. and Sahin, A.
Multiple Sclerosis Journal Experimental Translational and Clinical 7 (1): 2055217321998060. 1 January 2021

Hemodynamic phenotyping of transgenic rats with ubiquitous expression of an angiotensin-(1-7)-producing fusion protein.
Alves, D.T. and Mendes, L.F. and Sampaio, W.O. and Coimbra-Campos, L.M.C. and Vieira, M.A.R. and Ferreira, A.J. and Martins, A.S. and Popova, E. and Todiras, M. and Qadri, F. and Alenina, N. and Bader, M. and Santos, R.A.S. and Campagnole-Santos, M.J.
Clinical Science 135 (18): 2197-2216. 8 September 2021

Feasibility of a culturally adapted dietary weight-loss intervention among Ghanaian migrants in Berlin, Germany: the ADAPT study.
Amoah, S. and Ennin, R. and Sagoe, K. and Steinbrecher, A. and Pischon, T. and Mockenhaupt, F.P. and Danquah, I.
International Journal of Environmental Research and Public Health 18 (2): 510. 9 January 2021

Putative mobilized colistin resistance genes in the human gut microbiome.
Andrade, B.G.N. and Goris, T. and Afli, H. and Coutinho, F.H. and Dávila, A.M.R. and Cuadrat, R.R.C.
BMC Microbiology 21 : 220. 22 July 2021

Control of endothelial quiescence by FOXO-regulated metabolites.
Andrade, J. and Shi, C. and Costa, A.S.H. and Choi, J. and Kim, J. and Doddaballapur, A. and Sugino, T. and Ong, Y.T. and Castro, M. and Zimmermann, B. and Kaulich, M. and Guenther, S. and Wilhelm, K. and Kubota, Y. and Braun, T. and Koh, G.Y. and Grosso, A.R. and Frezza, C. and Potente, M.
Nature Cell Biology 23 : 413-423. April 2021

PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.
Appel, L.M. and Franke, V. and Bruno, M. and Grishkovskaya, I. and Kasiliauskaite, A. and Kaufmann, T. and Schoeberl, U.E. and Puchinger, M.G. and Kostrhon, S. and Ebenwaldner, C. and Sebesta, M. and Beltzung, E. and Mechtler, K. and Lin, G. and Vlasova, A. and Leeb, M. and Pavri, R. and Stark, A. and Akalin, A. and Stefl, R. and Bernecky, C. and Djinovic-Carugo, K. and Slade, D.
Nature Communications 12 (1): 6078. 19 October 2021

Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect.
Arlt, B. and Mastrobuoni, G. and Wuenschel, J. and Astrahantseff, K. and Eggert, A. and Kempa, S. and Deubzer, H.E.
Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1): 1282-1289. 30 June 2021

Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma.
Arlt, B. and Zasada, C. and Baum, K. and Wuenschel, J. and Mastrobuoni, G. and Lodrini, M. and Astrahantseff, K. and Winkler, A. and Schulte, J.H. and Finkler, S. and Forbes, M. and Hundsdoerfer, P. and Guergen, D. and Hoffmann, J. and Wolf, J. and Eggert, A. and Kempa, S. and Deubzer, H.E.
International Journal of Cancer 148 (5): 1219-1232. 1 March 2021

SNT: a unifying toolbox for quantification of neuronal anatomy.
Arshadi, C. and Günther, U. and Eddison, M. and Harrington, K.I.S. and Ferreira, T.A.
Nature Methods 18 : 374-377. April 2021

ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling.
Asaro, A. and Sinha, R. and Bakun, M. and Kalnytska, O. and Carlo-Spiewok, A.S. and Rubel, T. and Rozeboom, A. and Dadlez, M. and Kaminska, B. and Aronica, E. and Malik, A.R. and Willnow, T.E.
Journal of Cell Science 134 (20): jcs258894. 15 October 2021

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Aschenbrenner, A.C. and Mouktaroudi, M. and Krämer, B. and Oestreich, M. and Antonakos, N. and Nuesch-Germano, M. and Gkizeli, K. and Bonaguro, L. and Reusch, N. and Baßler, K. and Saridaki, M. and Knoll, R. and Pecht, T. and Kapellos, T.S. and Doulou, S. and Kröger, C. and Herbert, M. and Holsten, L. and Horne, A. and Gemünd, I.D. and Rovina, N. and Agrawal, S. and Dahm, K. and van Uelft, M. and Drews, A. and Lenkeit, L. and Bruse, N. and Gerretsen, J. and Gierlich, J. and Becker, M. and Händler, K. and Kraut, M. and Theis, H. and Mengiste, S. and Domenico, E. and Schulte-Schrepping, J. and Seep, L. and Raabe, J. and Hoffmeister, C. and ToVinh, M. and Keitel, V. and Rieke, G. and Talevi, V. and Skowasch, D. and Aziz, N.A. and Pickkers, P. and van de Veerdonk, F.L. and Netea, M.G. and Schultze, J.L. and Kox, M. and Breteler, M.M.B. and Nattermann, J. and Koutsoukou, A. and Giamarellos-Bourboulis, E.J. and Ulas, T.
Genome Medicine 13 (1): 7. 13 January 2021

Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation.
Aslam, M.A. and Alemdehy, M.F. and Kwesi-Maliepaard, E.M. and Muhaimin, F.I. and Caganova, M. and Pardieck, I.N. and van den Brand, T. and van Welsem, T. and de Rink, I. and Song, J.Y. and de Wit, E. and Arens, R. and Jacobs, H. and van Leeuwen, F.
EMBO Reports 22 (2): e51184. 3 February 2021

Pain, depression and quality of life in adults with MOG-antibody associated disease.
Asseyer, S. and Henke, E. and Trebst, C. and Hümmert, M.W. and Wildemann, B. and Jarius, S. and Ringelstein, M. and Aktas, O. and Pawlitzki, M. and Korsen, M. and Klotz, L. and Siebert, N. and Ruprecht, K. and Bellmann-Strobl, J. and Wernecke, K.D. and Häußler, V. and Havla, J. and Gahlen, A. and Gold, R. and Paul, F. and Kleiter, I. and Ayzenberg, I.
European Journal of Neurology 28 (5): 1645-1658. May 2021

AQP4-IgG autoimmunity in Japan and Germany: differences in clinical profiles and prognosis in seropositive neuromyelitis optica spectrum disorders.
Asseyer, S. and Masuda, H. and Mori, M. and Bellmann-Strobl, J. and Ruprecht, K. and Siebert, N. and Cooper, G. and Chien, C. and Duchow, A. and Schließeit, J. and Liu, J. and Sugimoto, K. and Uzawa, A. and Ohtani, R. and Paul, F. and Brandt, A.U. and Kuwabara, S. and Zimmermann, H.G.
Multiple Sclerosis Journal Experimental Translational and Clinical 7 (2): 205521732110068. 1 April 2021

Acceleration of TAA-induced liver fibrosis by stress exposure is associated with upregulation of nerve growth factor and glycopattern deviations.
Atorrasagasti, C. and Piccioni, F. and Borowski, S. and Tirado-González, I. and Freitag, N. and Cantero, M.J. and Bayo, J. and Mazzolini, G. and Alaniz, L.D. and Blois, S.M. and Garcia, M.G.
International Journal of Molecular Sciences 22 (10): 5055. 11 May 2021

Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease.
Audain, E. and Wilsdon, A. and Breckpot, J. and Izarzugaza, J.M. and Fitzgerald, T.W. and Kahlert, A.K. and Sifrim, A. and Wünnemann, F. and Perez-Riverol, Y. and Abdul-Khaliq, H. and Bak, M. and Bassett, A.S. and Benson, W.D. and Berger, F. and Daehnert, I. and Devriendt, K. and Dittrich, S. and Daubeney, P.E. and Garg, V. and Hackmann, K. and Hoff, K. and Hofmann, P. and Dombrowsky, G. and Pickardt, T. and Bauer, U. and Keavney, B.D. and Klaassen, S. and Kramer, H.H. and Marshall, C.R. and Milewicz, D.M. and Lemaire, S. and Coselli, J.S. and Mitchell, M.E. and Tomita-Mitchell, A. and Prakash, S.K. and Stamm, K. and Stewart, A.F.R. and Silversides, C.K. and Siebert, R. and Stiller, B. and Rosenfeld, J.A. and Vater, I. and Postma, A.V. and Caliebe, A. and Brook, J.D. and Andelfinger, G. and Hurles, M.E. and Thienpont, B. and Larsen, L.A. and Hitz, M.P.
PLoS Genetics 17 (7): e1009679. 29 July 2021

Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study.
Augustin, M. and Schommers, P. and Stecher, M. and Dewald, F. and Gieselmann, L. and Gruell, H. and Horn, C. and Vanshylla, K. and Cristanziano, V.D. and Osebold, L. and Roventa, M. and Riaz, T. and Tschernoster, N. and Altmueller, J. and Rose, L. and Salomon, S. and Priesner, V. and Luers, J.C. and Albus, C. and Rosenkranz, S. and Gathof, B. and Fätkenheuer, G. and Hallek, M. and Klein, F. and Suárez, I. and Lehmann, C.
The Lancet Regional Health - Europe 6 : 100122. July 2021

The magnitude of germinal center reactions is restricted by a fixed number of preexisting niches.
Avancena, P. and Song, T. and Yao, Y. and Fehlner-Peach, H. and Diamond, B. and Gu, H. and Rajewsky, K. and Zou, Y.R.
Proceedings of the National Academy of Sciences of the United States of America 118 (30): e2100576118. 27 July 2021

APOSTEL 2.0 recommendations for reporting quantitative optical coherence tomography studies.
Aytulun, A. and Cruz-Herranz, A. and Aktas, O. and Balcer, L.J. and Balk, L. and Barboni, P. and Blanco, A.A. and Calabresi, P.A. and Costello, F. and Sanchez-Dalmau, B. and DeBuc, D.C. and Feltgen, N. and Finger, R.P. and Frederiksen, J.L. and Frohman, E. and Frohman, T. and Garway-Heath, D. and Gabilondo, I. and Graves, J.S. and Green, A.J. and Hartung, H.P. and Havla, J. and Holz, F.G. and Imitola, J. and Kenney, R. and Klistorner, A. and Knier, B. and Korn, T. and Kolbe, S. and Krämer, J. and Lagrèze, W.A. and Leocani, L. and Maier, O. and Martínez-Lapiscina, E.H. and Meuth, S. and Outteryck, O. and Paul, F. and Petzold, A. and Pihl-Jensen, G. and Preiningerova, J.L. and Rebolleda, G. and Ringelstein, M. and Saidha, S. and Schippling, S. and Schuman, J.S. and Sergott, R.C. and Toosy, A. and Villoslada, P. and Wolf, S. and Yeh, E.A. and Yu-Wai-Man, P. and Zimmermann, H.G. and Brandt, A.U. and Albrecht, P.
Neurology 97 (2): 68-79. 13 July 2021

Pain, depression, and quality of life in neuromyelitis optica spectrum disorder: a cross-sectional study of 166 AQP4 antibody-seropositive patients.
Ayzenberg, I. and Richter, D. and Henke, E. and Asseyer, S. and Paul, F. and Trebst, C. and Hümmert, M.W. and Havla, J. and Kümpfel, T. and Ringelstein, M. and Aktas, O. and Wildemann, B. and Jarius, S. and Häußler, V. and Stellmann, J.P. and Senel, M. and Klotz, L. and Pellkofer, H.L. and Weber, M.S. and Pawlitzki, M. and Rommer, P.S. and Berthele, A. and Wernecke, K.D. and Hellwig, K. and Gold, R. and Kleiter, I.
Neurology Neuroimmunology & Neuroinflammation 8 (3): e985. May 2021

Metagenomic assessment of the global diversity and distribution of bacteria and fungi.
Bahram, M. and Netherway, T. and Frioux, C. and Ferretti, P. and Coelho, L.P. and Geisen, S. and Bork, P. and Hildebrand, F.
Environmental Microbiology 23 (1): 316-326. January 2021

Ultra-rapid emergency genomic diagnosis of Donahue syndrome in a preterm infant within 17 hours.
Bamborschke, D. and Özdemir, Ö. and Kreutzer, M. and Motameny, S. and Thiele, H. and Kribs, A. and Dötsch, J. and Altmüller, J. and Nürnberg, P. and Cirak, S.
American Journal of Medical Genetics A 185 (1): 90-96. January 2021

Extracellular matrix in heart Failure: role of ADAMTS5 in proteoglycan remodeling.
Barallobre-Barreiro, J. and Radovits, T. and Fava, M. and Mayr, U. and Lin, W.Y. and Ermolaeva, E. and Martínez-López, D. and Lindberg, E.L. and Duregotti, E. and Daróczi, L. and Hasman, M. and Schmidt, L.E. and Singh, B. and Lu, R. and Baig, F. and Siedlar, A.M. and Cuello, F. and Catibog, N. and Theofilatos, K. and Shah, A.M. and Crespo-Leiro, M.G. and Doménech, N. and Hübner, N. and Merkely, B. and Mayr, M.
Circulation 144 (25): 2021-2034. 21 December 2021

Hearing and vocalizations in the naked mole-rat.
Barker, A.J. and Koch, U. and Lewin, G.R. and Pyott, S.J.
Advances in Experimental Medicine and Biology 1319 (1319): 157-195. 24 August 2021

Cultural transmission of vocal dialect in the naked mole-rat.
Barker, A.J. and Veviurko, G. and Bennett, N.C. and Hart, D.W. and Mograby, L. and Lewin, G.R.
Science 371 (6528): 503-507. 29 January 2021

Quantifying technical confounders in microbiome studies.
Bartolomaeus, T.U.P. and Birkner, T. and Bartolomaeus, H. and Löber, U. and Avery, E.G. and Mähler, A. and Weber, D. and Kochlik, B. and Balogh, A. and Wilck, N. and Boschmann, M. and Müller, D.N. and Markó, L. and Forslund, S.K.
Cardiovascular Research 117 (3): 863-875. 1 March 2021

Isolation, culture, and genetic engineering of mammalian primary pigment epithelial cells for non-viral gene therapy.
Bascuas, T. and Kropp, M. and Harmening, N. and Wong, B.M. and Johnen, S. and Izsvák, Z. and Thumann, G.
Journal of Visualized Experiments (168): e62145. 26 February 2021

CD40 activity on mesenchymal cells negatively regulates OX40L to maintain bone marrow immune homeostasis under stress conditions.
Bassani, B. and Tripodo, C. and Portararo, P. and Gulino, A. and Botti, L. and Chiodoni, C. and Jachetti, E. and Bolli, N. and Ciciarello, M. and Joehrens, K. and Anagnostopoulos, I. and Na, I.K. and Curti, A. and Colombo, M.P. and Sangaletti, S.
Frontiers in Immunology 12 : 662048. 18 May 2021

Diurnal variations in the expression of core-clock genes correlate with resting muscle properties and predict fluctuations in exercise performance across the day.
Basti, A. and Yalçin, M. and Herms, D. and Hesse, J. and Aboumanify, O. and Li, Y. and Aretz, Z. and Garmshausen, J. and El-Athman, R. and Hastermann, M. and Blottner, D. and Relógio, A.
BMJ Open Sport & Exercise Medicine 7 (1): e000876. 10 February 2021

Vasohibin-1 selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk.
Bastos de Oliveira, M. and Meier, K. and Jung, S. and Bartels-Klein, E. and Coxam, B. and Geudens, I. and Szymborska, A. and Skoczylas, R. and Fechner, I. and Koltowska, K. and Gerhardt, H.
Development 148 (4): dev194993. 19 February 2021

Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes.
Bathe-Peters, M. and Gmach, P. and Boltz, H.H. and Einsiedel, J. and Gotthardt, M. and Hübner, H. and Gmeiner, P. and Lohse, M.J. and Annibale, P.
Proceedings of the National Academy of Sciences of the United States of America 118 (23): e2101119118. 8 June 2021

A backward-mode optical-resolution photoacoustic microscope for 3D imaging using a planar Fabry-Pérot sensor.
Baumann, E. and Pohle, U. and Zhang, E. and Allen, T. and Villringer, C. and Pulwer, S. and Gerhardt, H. and Laufer, J.
Photoacoustics 24 : 100293. December 2021

Protein intake, metabolic status and the gut microbiota in different ethnicities: results from two independent cohorts.
Bel Lassen, P. and Attaye, I. and Adriouch, S. and Nicolaou, M. and Aron-Wisnewsky, J. and Nielsen, T. and Chakaroun, R. and Le Chatelier, E. and Forslund, S. and Belda, E. and Bork, P. and Bäckhed, F. and Stumvoll, M. and Pedersen, O. and Herrema, H. and Groen, A. and Pinto-Sietsma, S.J. and Zwinderman, A. and Nieuwdorp, M. and Clement, K.
Nutrients 13 (9): 3159. September 2021

Epigallocatechin gallate in relapsing-remitting multiple sclerosis: a randomized, placebo-controlled trial.
Bellmann-Strobl, J. and Paul, F. and Wuerfel, J. and Dörr, J. and Infante-Duarte, C. and Heidrich, E. and Körtgen, B. and Brandt, A. and Pfüller, C. and Radbruch, H. and Rust, R. and Siffrin, V. and Aktas, O. and Heesen, C. and Faiss, J. and Hoffmann, F. and Lorenz, M. and Zimmermann, B. and Groppa, S. and Wernecke, K.D. and Zipp, F.
Neurology Neuroimmunology & Neuroinflammation 8 (3): e981. May 2021

Using DNA sequencing data to quantify T cell fraction and therapy response.
Bentham, R. and Litchfield, K. and Watkins, T.B.K. and Lim, E.L. and Rosenthal, R. and Martínez-Ruiz, C. and Hiley, C.T. and Bakir, M.A. and Salgado, R. and Moore, D.A. and Jamal-Hanjani, M. and Swanton, C. and McGranahan, N.
Nature 597 (7877): 555-560. 23 September 2021

Structure of the Yersinia injectisome in intracellular host cell phagosomes revealed by cryo FIB electron tomography.
Berger, C. and Ravelli, R.B.G. and López-Iglesias, C. and Kudryashev, M. and Diepold, A. and Peters, P.J.
Journal of Structural Biology 213 (1): 107701. March 2021

Deep tissue scattering compensation with three-photon F-SHARP.
Berlage, C. and Tantirigama, M.L.S. and Babot, M. and Di Battista, D. and Whitmire, C. and Papadopoulos, I.N. and Poulet, J.F.A. and Larkum, M. and Judkewitz, B.
Optica 8 (12): 1613-1619. 20 December 2021

Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis.
Bernardo-Faura, M. and Rinas, M. and Wirbel, J. and Pertsovskaya, I. and Pliaka, V. and Messinis, D.E. and Vila, G. and Sakellaropoulos, T. and Faigle, W. and Stridh, P. and Behrens, J.R. and Olsson, T. and Martin, R. and Paul, F. and Alexopoulos, L.G. and Villoslada, P. and Saez-Rodriguez, J.
Genome Medicine 13 (1): 117. 16 July 2021

CARDIOKIN1: computational assessment of myocardial metabolic capability in healthy controls and patients with valve diseases.
Berndt, N. and Eckstein, J. and Wallach, I. and Nordmeyer, S. and Kelm, M. and Kirchner, M. and Goubergrits, L. and Schafstedde, M. and Hennemuth, A. and Kraus, M. and Grune, T. and Mertins, P. and Kuehne, T. and Holzhütter, H.G.
Circulation 144 (24): 1926-1939. 14 December 2021

Immunological and pathological outcomes of SARS-CoV-2 challenge following formalin-inactivated vaccine in ferrets and rhesus macaques.
Bewley, K.R. and Gooch, K. and Thomas, K.M. and Longet, S. and Wiblin, N. and Hunter, L. and Chan, K. and Brown, P. and Russell, R. A. and Ho, C. and Slack, G. and Humphries, H.E. and Alden, L. and Allen, L. and Aram, M. and Baker, N. and Brunt, E. and Cobb, R. and Fotheringham, S. and Harris, D. and Kennard, C. and Leung, S. and Ryan, K. and Tolley, H. and Wand, N. and White, A. and Sibley, L. and Sarfas, C. and Pearson, G. and Rayner, E. and Xue, X. and Lambe, T. and Charlton, S. and Gilbert, S. and Sattentau, Q.J. and Gleeson, F. and Hall, Y. and Funnell, S. and Sharpe, S. and Salguero, F.J. and Gorringe, A. and Carroll, M.
Science Advances 7 (37): eabg7996. 10 September 2021

Skin-resident innate lymphoid cells converge on a pathogenic effector state.
Bielecki, P. and Riesenfeld, S.J. and Hütter, J.C. and Torlai Triglia, E. and Kowalczyk, M.S. and Ricardo-Gonzalez, R.R. and Lian, M. and Amezcua Vesely, M.C. and Kroehling, L. and Xu, H. and Slyper, M. and Muus, C. and Ludwig, L.S. and Christian, E. and Tao, L. and Kedaigle, A.J. and Steach, H.R. and York, A.G. and Skadow, M.H. and Yaghoubi, P. and Dionne, D. and Jarret, A. and McGee, H.M. and Porter, C.B.M. and Licona-Limón, P. and Bailis, W. and Jackson, R. and Gagliani, N. and Gasteiger, G. and Locksley, R.M. and Regev, A. and Flavell, R.A.
Nature 592 (7852): 128-132. 1 April 2021

Exposure to perfluoroalkyl substances and blood pressure in pregnancy among 1436 women from the Odense Child Cohort.
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Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma.
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Time to diagnosis in multiple sclerosis: epidemiological data from the German Multiple Sclerosis Registry.
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Progressive myocardial injury in myotonic dystrophy type II and facioscapulohumeral muscular dystrophy 1: a cardiovascular magnetic resonance follow-up study.
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Uncovering de novo gene birth in yeast using deep transcriptomics.
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Nature Communications 12 (1): 604. 27 January 2021

Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.
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Nature Communications 12 (1): 5395. 13 September 2021

Placental glycoredox dysregulation associated with disease progression in an animal model of superimposed preeclampsia.
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Cells 10 (4): 800. April 2021

Transverse aortic constriction induces gut barrier alterations, microbiota remodeling and systemic inflammation.
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Scientific Reports 11 (1): 7404. 1 April 2021

SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity.
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Nature Communications 12 (1): 3965. 25 June 2021

Phenotyping placental oxygenation in Lgals1 deficient mice using (19)F MRI.
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Scientific Reports 11 (1): 2126. 22 January 2021

Comprehensive CRISPR-Cas9 screens identify genetic determinants of drug responsiveness in multiple myeloma.
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Blood Advances 5 (9): 2391-2402. 11 May 2021

Quantitative spectroscopy of single molecule interaction times.
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Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis.
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Clinical and Translational Allergy 11 (5): e12045. July 2021

PET-guided omission of radiotherapy in early-stage unfavourable Hodgkin lymphoma (GHSG HD17): a multicentre, open-label, randomised, phase 3 trial.
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Asymmetric cell division shapes naive and virtual memory T-cell immunity during ageing.
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Nature Communications 12 (1): 2715. 11 May 2021

Impact of a specialised palliative care intervention in patients with advanced soft tissue sarcoma - a single-centre retrospective analysis.
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BMC Palliative Care 20 (1): 16. 14 January 2021

Association of a marker of N-acetylglucosamine with progressive multiple sclerosis and neurodegeneration.
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JAMA Neurology 78 (7): 842-852. July 2021

M01 as a novel drug enhancer for specifically targeting the blood-brain barrier.
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Journal of Controlled Release 330 : 137-148. 10 August 2021

DOTAM-based, targeted, activatable fluorescent probes for the highly sensitive and selective detection of cancer cells.
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Bioconjugate Chemistry 32 (4): 702-712. 21 April 2021

Human and preclinical studies of the host-gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health.
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Does the proteasome inhibitor bortezomib sensitize to DNA-damaging therapy in gastroenteropancreatic neuroendocrine neoplasms? - A preclinical assessment in vitro and in vivo.
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Neoplasia 23 (1): 80-98. January 2021

NF-κB determines Paneth versus goblet cell fate decision in the small intestine.
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Development 148 (21): dev199683. November 2021

An integrated host-microbiome response to atrazine exposure mediates toxicity in Drosophila.
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Mitochondria in neurogenesis: implications for mitochondrial diseases.
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Stem Cells 39 (10): 1289-1297. October 2021

Radiation driven chemistry in biomolecules -- is (V)UV involved in the bioactivity of argon jet plasmas?
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Frontiers in Physics 9 : 759005. 14 December 2021

Coregulation of gene expression by White collar 1 and phytochrome in Ustilago maydis.
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Fungal Genetics and Biology 152 : 103570. July 2021

MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
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Nature Communications 12 (1): 5505. 17 September 2021

Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage.
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Journal of Biological Chemistry 297 (4): 101224. October 2021

DenoiSeg: joint denoising and segmentation.
Buchholz, T.O. and Prakash, M. and Schmidt, D. and Krull, A. and Jug, F.
Lecture Notes in Computer Science 12535 : 324-337. 10 January 2021

Systematic identification of A-to-I RNA editing in zebrafish development and adult organs.
Buchumenski, I. and Holler, K. and Appelbaum, L. and Eisenberg, E. and Junker, J.P. and Levanon, E.Y.
Nucleic Acids Research 49 (8): 4325-4337. 7 May 2021

Structural evidence of active site adaptability towards different sized substrates of aromatic amino acid aminotransferase from Psychrobacter sp. B6.
Bujacz, A. and Rum, J. and Rutkiewicz, M. and Pietrzyk-Brzezinska, A.J. and Bujacz, G.
Materials 14 (12): 3351. 2 June 2021

CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin's lymphoma and tumor-supportive follicular T helper cells.
Bunse, M. and Pfeilschifter, J. and Bluhm, J. and Zschummel, M. and Joedicke, J.J. and Wirges, A. and Stark, H. and Kretschmer, V. and Chmielewski, M. and Uckert, W. and Abken, H. and Westermann, J. and Rehm, A. and Höpken, U.E.
Nature Communications 12 (1): 240. 11 January 2021

Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K. and Kny, M. and Huang, N. and Klassert, T.E. and Stock, M. and Hahn, A. and Graeger, S. and Todiras, M. and Schmidt, S. and Chamling, B. and Willenbrock, M. and Groß, S. and Biedenweg, D. and Heuser, A. and Scheidereit, C. and Butter, C. and Felix, S.B. and Otto, O. and Luft, F.C. and Slevogt, H. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 12 (6): 1653-1668. December 2021

Gene therapy "Made in Germany": a historical perspective, analysis of the status quo, and recommendations for action by the German Society for Gene Therapy.
Büning, H. and Fehse, B. and Ivics, Z. and Kochanek, S. and Koehl, U. and Kupatt, C. and Mussolino, C. and Nettelbeck, D.M. and Schambach, A. and Uckert, W. and Wagner, E. and Cathomen, T.
Human Gene Therapy 32 (19-20): 987-996. 18 October 2021

Single cell biology - a Keystone Symposia report.
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Annals of the New York Academy of Sciences 1506 (1): 74-97. December 2021

Cancer stem cells: advances in biology and clinical translation -- a Keystone Symposia report.
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Annals of the New York Academy of Sciences 1506 (1): 142–163. December 2021

The delivery challenge of genome editing in human epithelia.
Calderón, M. and Hedtrich, S.
Advanced Healthcare Materials 10 (19): e2100847. October 2021

DDX3 depletion represses translation of mRNAs with complex 5' UTRs.
Calviello, L. and Venkataramanan, S. and Rogowski, K.J. and Wyler, E. and Wilkins, K. and Tejura, M. and Thai, B. and Krol, J. and Filipowicz, W. and Landthaler, M. and Floor, S.N.
Nucleic Acids Research 49 (9): 5336-5350. May 2021

Transcriptional signatures regulated by TRPC1/C4-mediated Background Ca(2+) entry after pressure-overload induced cardiac remodelling.
Camacho Londoño, J.E. and Kuryshev, V. and Zorn, M. and Saar, K. and Tian, Q. and Hübner, N. and Nawroth, P. and Dietrich, A. and Birnbaumer, L. and Lipp, P. and Dieterich, C. and Freichel, M.
Progress in Biophysics and Molecular Biology 159 : 86-104. January 2021

Hydrogels containing budesonide-loaded nanoparticles to facilitate percutaneous absorption for atopic dermatitis treatment applications.
Campos, E.V.R. and Proença, P.L.F. and Costa, T.G.d. and de Lima, R. and Hedtrich, S. and Fraceto, L.F. and de Araujo, D.R.
ACS Applied Polymer Materials 3 (9): 4436-4449. 10 September 2021

Quantitative assessment of renal perfusion and oxygenation by invasive probes: basic concepts.
Cantow, K. and Evans, R.G. and Grosenick, D. and Gladytz, T. and Niendorf, T. and Flemming, B. and Seeliger, E.
Methods in Molecular Biology 2216 : 89-107. 2021

Monitoring renal hemodynamics and oxygenation by invasive probes: experimental protocol.
Cantow, K. and Ladwig-Wiegard, M. and Flemming, B. and Pohlmann, A. and Niendorf, T. and Seeliger, E.
Methods in Molecular Biology 2216 : 327-347. 2021

Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ.
Cappelletti, V. and Hauser, T. and Piazza, I. and Pepelnjak, M. and Malinovska, L. and Fuhrer, T. and Li, Y. and Dörig, C. and Boersema, P. and Gillet, L. and Grossbach, J. and Dugourd, A. and Saez-Rodriguez, J. and Beyer, A. and Zamboni, N. and Caflisch, A. and de Souza, N. and Picotti, P.
Cell 184 (2): 545-559. 21 January 2021

Ecological factors influence balancing selection on leaf chemical profiles of a wildflower.
Carley, L.N. and Mojica, J.P. and Wang, B. and Chen, C.Y. and Lin, Y.P. and Prasad, K.V.S.K and Chan, E. and Hsu, C.W. and Keith, R. and Nuñez, C.L. and Olson-Manning, C.F. and Rushworth, C.A. and Wagner, M.R. and Wang, J. and Yeh, P.M. and Reichelt, M. and Ghattas, K. and Gershenzon, J. and Lee, C.R. and Mitchell-Olds, T.
Nature Ecology & Evolution 5 : 1135–1144. August 2021

Regulating T-cell differentiation through the polyamine spermidine.
Carriche, G.M. and Almeida, L. and Stüve, P. and Velasquez, L. and Dhillon-LaBrooy, A. and Roy, U. and Lindenberg, M. and Strowig, T. and Plaza-Sirvent, C. and Schmitz, I. and Lochner, M. and Simon, A.K. and Sparwasser, T.
Journal of Allergy and Clinical Immunology 147 (1): 335-348. January 2021

Enhanced properties of a benzimidazole benzylpyrazole lysine demethylase inhibitor: mechanism-of-action, binding site analysis, and activity in cellular models of prostate cancer.
Carter, D.M. and Specker, E. and Malecki, P.H. and Przygodda, J. and Dudaniec, K. and Weiss, M.S. and Heinemann, U. and Nazaré, M. and Gohlke, U.
Journal of Medicinal Chemistry 64 (19): 14266-14282. 14 October 2021

Heterogeneity of diabetes: β-cells, phenotypes, and precision medicine: proceedings of an international symposium of the canadian institutes of Health Research’s Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases.
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Canadian Journal of Diabetes 45 (8): 697-713. December 2021

Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly.
Cereghetti, G. and Wilson-Zbinden, C. and Kissling, V.M. and Diether, M. and Arm, A. and Yoo, H. and Piazza, I. and Saad, S. and Picotti, P. and Drummond, D.A. and Sauer, U. and Dechant, R. and Peter, M.
Nature Cell Biology 23 (10): 1085-1094. October 2021

Functional characterization of ovine dorsal root ganglion neurons reveal peripheral sensitization after osteochondral defect.
Chakrabarti, S. and Ai, M. and Wong, K. and Newell, K. and Henson, F.M.D. and Smith, E.S.J.
eNeuro 8 (5): ENEURO.0237-21.2021. September 2021

Design and testing of efficient mucus-penetrating nanogels-pitfalls of preclinical testing and lessons learned.
Charbaji, R. and Kar, M. and Theune, L.E. and Bergueiro, J. and Eichhorst, A. and Navarro, L. and Graff, P. and Stumpff, F. and Calderón, M. and Hedtrich, S.
Small 17 (23): e2007963. 10 June 2021

R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage.
Chatzidoukaki, O. and Stratigi, K. and Goulielmaki, E. and Niotis, G. and Akalestou-Clocher, A. and Gkirtzimanaki, K. and Zafeiropoulos, A. and Altmüller, J. and Topalis, P. and Garinis, G.A.
Science Advances 7 (47): eabj5769. 19 November 2021

Transformation of SOX9(+) cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma.
Chen, J. and Debebe, A. and Zeng, N. and Kopp, J. and He, L. and Sander, M. and Stiles, B.L.
Scientific Reports 11 (1): 11823. 3 June 2021

Interpreting type 1 diabetes risk with genetics and single-cell epigenomics.
Chiou, J. and Geusz, R.J. and Okino, M.L. and Han, J.Y. and Miller, M. and Melton, R. and Beebe, E. and Benaglio, P. and Huang, S. and Korgaonkar, K. and Heller, S. and Kleger, A. and Preissl, S. and Gorkin, D.U. and Sander, M. and Gaulton, K.J.
Nature 594 (7863): 398-402. 17 June 2021

Single-cell chromatin accessibility identifies pancreatic islet cell type- and state-specific regulatory programs of diabetes risk.
Chiou, J. and Zeng, C. and Cheng, Z. and Han, J.Y. and Schlichting, M. and Miller, M. and Mendez, R. and Huang, S. and Wang, J. and Sui, Y. and Deogaygay, A. and Okino, M.L. and Qiu, Y. and Sun, Y. and Kudtarkar, P. and Fang, R. and Preissl, S. and Sander, M. and Gorkin, D.U. and Gaulton, K.J.
Nature Genetics 53 (4): 455-466. April 2021

FEZ1 forms complexes with CRMP1 and DCC to regulate axon and dendrite development.
Chua, J.Y. and Ng, S.J. and Yagensky, O. and Wanker, E.E. and Chua, J.J.E.
eNeuro 8 (2): ENEURO.0193-20.2021. 26 March 2021

Quantitative analysis of renal perfusion by arterial spin labeling.
Chuang, K.H. and Kober, F. and Ku, M.C.
Methods in Molecular Biology 2216 : 655-666. 2021

Renal blood flow using arterial spin labeling (ASL) MRI: experimental protocol and principles.
Chuang, K.H. and Meier, M. and Fernández-Seara, M.A. and Kober, F. and Ku, M.C.
Methods in Molecular Biology 2216 : 443-453. 2021

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules.
Cipriani, P.G. and Bay, O. and Zinno, J. and Gutwein, M. and Gan, H.H. and Mayya, V.K. and Chung, G. and Chen, J.X. and Fahs, H. and Guan, Y. and Duchaine, T.F. and Selbach, M. and Piano, F. and Gunsalus, K.C.
eLife 10 : e60833. 3 August 2021

Dynamic and equilibrium properties of finite-size polymer models of chromosome folding.
Conte, M. and Fiorillo, L. and Annunziatella, C. and Esposito, A. and Musella, F. and Abraham, A. and Bianco, S. and Chiariello, A.M.
Physical Review E 104 (5): 054402. 10 November 2021

Assessing attacks and treatment response rates among adult patients with NMOSD and MOGAD: data from a nationwide registry in Argentina.
Contentti, E.C. and Lopez, P.A. and Pettinicchi, J.P. and Criniti, J. and Pappolla, A. and Miguez, J. and Patrucco, L. and Carnero Contentti, E. and Liwacki, S. and Tkachuk, V. and Balbuena, M.E. and Vrech, C. and Deri, N. and Correale, J. and Marrodan, M. and Ysrraelit, M.C. and Leguizamon, F. and Luetic, G. and Menichini, M.L. and Tavolini, D. and Mainella, C. and Zanga, G. and Burgos, M. and Hryb, J. and Barboza, A. and Lazaro, L. and Alonso, R. and Liguori, N.F. and Nadur, D. and Chercoff, A. and Alonso Serena, M. and Caride, A. and Paul, F. and Rojas, J.I.
Multiple Sclerosis Journal Experimental Translational and Clinical 7 (3): 20552173211032334. 1 July 2021

Longitudinal analysis of T1w/T2w ratio in patients with multiple sclerosis from first clinical presentation.
Cooper, G. and Chien, C. and Zimmermann, H. and Bellmann-Strobl, J. and Ruprecht, K. and Kuchling, J. and Asseyer, S. and Brandt, A.U. and Scheel, M. and Finke, C. and Paul, F.
Multiple Sclerosis Journal 27 (14): 2180-2190. December 2021

From forensics to clinical research: expanding the variant calling pipeline for the precision ID mtDNA whole genome panel.
Cortes-Figueiredo, F. and Carvalho, F.S. and Fonseca, A.C. and Paul, F. and Ferro, J.M. and Schönherr, S. and Weissensteiner, H. and Morais, V.A.
International Journal of Molecular Sciences 22 (21): 12031. 6 November 2021

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition).
Cossarizza, A. and Chang, H.D. and Radbruch, A. and Abrignani, S. and Addo, R. and Akdis, M. and Andrä, I. and Andreata, F. and Annunziato, F. and Arranz, E. and Bacher, P. and Bari, S. and Barnaba, V. and Barros-Martins, J. and Baumjohann, D. and Beccaria, C.G. and Bernardo, D. and Boardman, D.A. and Borger, J. and Böttcher, C. and Brockmann, L. and Burns, M. and Busch, D.H. and Cameron, G. and Cammarata, I. and Cassotta, A. and Chang, Y. and Chirdo, F.G. and Christakou, E. and Čičin-Šain, L. and Cook, L. and Corbett, A.J. and Cornelis, R. and Cosmi, L. and Davey, M.S. and De Biasi, S. and De Simone, G. and Del Zotto, G. and Delacher, M. and Di Rosa, F. and Santo, J.D. and Diefenbach, A. and Dong, J. and Dörner, T. and Dress, R.J. and Dutertre, C.A. and Eckle, S.B.G. and Eede, P. and Evrard, M. and Falk, C.S. and Feuerer, M. and Fillatreau, S. and Fiz-Lopez, A. and Follo, M. and Foulds, G.A. and Fröbel, J. and Gagliani, N. and Galletti, G. and Gangaev, A. and Garbi, N. and Garrote, J.A. and Geginat, J. and Gherardin, N.A. and Gibellini, L. and Ginhoux, F. and Godfrey, D.I. and Gruarin, P. and Haftmann, C. and Hansmann, L. and Harpur, C.M. and Hayday, A.C. and Heine, G. and Hernández, D.C. and Herrmann, M. and Hoelsken, O. and Huang, Q. and Huber, S. and Huber, J.E. and Huehn, J. and Hundemer, M. and Hwang, W.Y.K. and Iannacone, M. and Ivison, S.M. and Jäck, H.M. and Jani, P.K. and Keller, B. and Kessler, N. and Ketelaars, S. and Knop, L. and Knopf, J. and Koay, H.F. and Kobow, K. and Kriegsmann, K. and Kristyanto, H. and Krueger, A. and Kuehne, J.F. and Kunze-Schumacher, H. and Kvistborg, P. and Kwok, I. and Latorre, D. and Lenz, D. and Levings, M.K. and Lino, A.C. and Liotta, F. and Long, H.M. and Lugli, E. and MacDonald, K.N. and Maggi, L. and Maini, M.K. and Mair, F. and Manta, C. and Manz, R.S. and Mashreghi, M.F. and Mazzoni, A. and McCluskey, J. and Mei, H.E. and Melchers, F. and Melzer, S. and Mielenz, D. and Monin, L. and Moretta, L. and Multhoff, G. and Muñoz, L.E. and Muñoz-Ruiz, M. and Muscate, F. and Natalini, A. and Neumann, K. and Ng, L.G. and Niedobitek, A. and Niemz, J. and Almeida, L.N. and Notarbartolo, S. and Ostendorf, L. and Pallett, L.J. and Patel, A.A. and Percin, G.I. and Peruzzi, G. and Pinti, M. and Pockley, A.G. and Pracht, K. and Prinz, I. and Pujol-Autonell, I. and Pulvirenti, N. and Quatrini, L. and Quinn, K.M. and Radbruch, H. and Rhys, H. and Rodrigo, M.B. and Romagnani, C. and Saggau, C. and Sakaguchi, S. and Sallusto, F. and Sanderink, L. and Sandrock, I. and Schauer, C. and Scheffold, A. and Scherer, H.U. and Schiemann, M. and Schildberg, F.A. and Schober, K. and Schoen, J. and Schuh, W. and Schüler, T. and Schulz, A.R. and Schulz, S. and Schulze, J. and Simonetti, S. and Singh, J. and Sitnik, K.M. and Stark, R. and Starossom, S. and Stehle, C. and Szelinski, F. and Tan, L. and Tarnok, A. and Tornack, J. and Tree, T.I.M. and van Beek, J.J.P. and van de Veen, W. and van Gisbergen, K. and Vasco, C. and Verheyden, N.A. and von Borstel, A. and Ward-Hartstonge, K.A. and Warnatz, K. and Waskow, C. and Wiedemann, A. and Wilharm, A. and Wing, J. and Wirz, O. and Wittner, J. and Yang, J.H.M. and Yang, J.
European Journal of Immunology 51 (12): 2708-3145. December 2021

Deletion of muscarinic acetylcholine receptor 3 in microglia impacts brain ischemic injury.
Costa, A. and Haage, V. and Yang, S. and Wegner, S. and Ersoy, B. and Ugursu, B. and Rex, A. and Kronenberg, G. and Gertz, K. and Endres, M. and Wolf, S.A. and Kettenmann, H.
Brain Behavior and Immunity 91 : 89-104. January 2021

Sensitivity analysis of the primary endpoint from the N-MOmentum study of inebilizumab in NMOSD.
Cree, B.A.C. and Bennett, J.L. and Kim, H.J. and Weinshenker, B.G. and Pittock, S.J. and Wingerchuk, D. and Fujihara, K. and Paul, F. and Cutter, G.R. and Marignier, R. and Green, A.J. and Aktas, O. and Hartung, H.P. and Williams, I.M. and Drappa, J. and She, D. and Cimbora, D. and Rees, W. and Ratchford, J.N. and Katz, E.
Multiple Sclerosis Journal 27 (13): 2052-2061. 1 November 2021

Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis.
Cruz-Herranz, A. and Oertel, F.C. and Kim, K. and Cantó, E. and Timmons, G. and Sin, J.H. and Devereux, M. and Baker, N. and Michel, B. and Schubert, R.D. and Rani, L. and Cordano, C. and Baranzini, S.E. and Green, A.J.
JCI Insight 6 (11): e149228. 8 June 2021

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation.
Cuello, F. and Knaust, A.E. and Saleem, U. and Loos, M. and Raabe, J. and Mosqueira, D. and Laufer, S. and Schweizer, M. and Kraak, P. and Flenner, F. and Ulmer, B.M and Braren, I. and Yin, X. and Theofilatos, K. and Ruiz-Orera, J. and Patone, G. and Klampe, B. and Schulze, T. and Piasecki, A. and Pinto, Y. and Vink, A. and Hübner, N. and Harding, S. and Mayr, M. and Denning, C. and Eschenhagen, T. and Hansen, A.
EMBO Molecular Medicine 13 (6): e13074. 7 June 2021

Reduction of tissue Na(+) accumulation after renal transplantation.
Dahlmann, A. and Linz, P. and Zucker, I. and Haag, V. and Jantsch, J. and Dienemann, T. and Nagel, A.M. and Neubert, P. and Rosenhauer, D. and Rauh, M. and Horn, S. and Müller, D.N. and Schiffer, M. and Luft, F.C. and Uder, M. and Kopp, C.
Kidney International Reports 6 (9): 2338-2347. September 2021

Combination of Wnt/β-catenin targets S100A4 and DKK1 improves prognosis of human colorectal cancer.
Dahlmann, M. and Monks, A. and Harris, E.D. and Kobelt, D. and Osterland, M. and Khaireddine, F. and Herrmann, P. and Kemmner, W. and Burock, S. and Walther, W. and Shoemaker, R.H. and Stein, U.
Cancers 14 (1): 37. 22 December 2021

A bioinformatic pipeline to identify biomarkers for metastasis formation from RNA sequencing data.
Dahlmann, M. and Stein, U.S.
Methods in Molecular Biology 2294 : 221-238. 2021

Early bilirubinemia after allogeneic stem cell transplantation - an endothelial complication.
Dai, H. and Penack, O. and Radujkovic, A. and Schult, D. and Majer-Lauterbach, J. and Blau, I.W. and Bullinger, L. and Jiang, S. and Müller-Tidow, C. and Dreger, P. and Luft, T.
Bone Marrow Transplantation 56 (7): 1573-1583. July 2021

Clinical and genetic characterization of PYROXD1-related myopathy patients from Turkey.
Daimagüler, H.S. and Akpulat, U. and Özdemir, Ö. and Yis, U. and Güngör, S. and Talim, B. and Diniz, G. and Baydan, F. and Thiele, H. and Altmüller, J. and Nürnberg, P. and Cirak, S.
American Journal of Medical Genetics A 185 (6): 1678-1690. 14 May 2021

A homology independent sequence replacement strategy in human cells using a CRISPR nuclease.
Danner, E. and Lebedin, M. and de la Rosa, K. and Kühn, R.
Open Biology 11 (1): 200283. January 2021

Thyrotropin receptor-specific lymphocytes in adenovirus-TSHR-immunized native and human leukocyte antigen-DR3-transgenic mice and in Graves' disease patient blood.
Degen, H. and Gavvovidis, I. and Blankenstein, T. and Uhland, K. and Ungerer, M.
Thyroid 31 (6): 950-963. June 2021

Hardware considerations for preclinical magnetic resonance of the kidney.
Delgado, P.R. and Küstermann, E. and Kühne, A. and Millward, J.M. and Niendorf, T. and Pohlmann, A. and Meier, M.
Methods in Molecular Biology 2216 : 131-155. 2021

A medullary centre for lapping in mice.
Dempsey, B. and Sungeelee, S. and Bokiniec, P. and Chettouh, Z. and Diem, S. and Autran, S. and Harrell, E.R. and Poulet, J.F.A. and Birchmeier, C. and Carey, H. and Genovesio, A. and McMullan, S. and Goridis, C. and Fortin, G. and Brunet, J.F.
Nature Communications 12 : 6307. 2 November 2021

Elevated Flt3L predicts long-term survival in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms.
Detjen, K.M. and Otto, R. and Giesecke, Y. and Geisler, L. and Riemer, P. and Jann, H. and Grötzinger, C. and Sers, C. and Pascher, A. and Lüdde, T. and Leser, U. and Wiedenmann, B. and Sigal, M. and Tacke, F. and Roderburg, C. and Hammerich, L.
Cancers 13 (17): 4463. 1 September 2021

„Liquid biopsies“ als neue Diagnostikplattform in der pädiatrischen Onkologie [Liquid biopsies as a new diagnostic platform in pediatric oncology].
Deubzer, H.E. and Eggert, A. and Pajtler, K. W.
Onkologe 27 (5): 458-463. May 2021

An agenda-setting paper on data sharing platforms: euCanSHare workshop.
Devriendt, T. and Ammann, C. and Asselbergs, F.W. and Bernier, A. and Costas, R. and Friedrich, M.G. and Gelpi, J.L. and Jarvelin, M.R. and Kuulasmaa, K. and Lekadir, K. and Mayrhofer, M.T. and Papez, V. and Pasterkamp, G. and Petersen, S.E. and Schmidt, C.O. and Schulz-Menger, J. and Söderberg, S. and Shabani, M. and Veronesi, G. and Viezzer, D.S. and Borry, P.
Open Research Europe 1 : 80. 23 November 2021

From tube to structure: SPA Cryo-EM workflow using apoferritin as an example.
Diebolder, C.A. and Dillard, R.S. and Renault, L.
Methods in Molecular Biology 2305 (2305): 229-256. 6 May 2021

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4.
Diener, J. and Baggiolini, A. and Pernebrink, M. and Dalcher, D. and Lerra, L. and Cheng, P.F. and Varum, S. and Häusel, J. and Stierli, S. and Treier, M. and Studer, L. and Basler, K. and Levesque, M.P. and Dummer, R. and Santoro, R. and Cantù, C. and Sommer, L.
Nature Communications 12 (1): 5056. 20 August 2021

Structure of the merozoite surface protein 1 from Plasmodium falciparum.
Dijkman, P.M. and Marzluf, T. and Zhang, Y. and Chang, S.Y.S. and Helm, D. and Lanzer, M. and Bujard, H. and Kudryashev, M.
Science Advances 7 (23): eabg0465. June 2021

COVID19-associated cardiomyocyte dysfunction, arrhythmias and the effect of Canakinumab.
Dimai, S. and Semmler, L. and Prabhu, A. and Stachelscheid, H. and Huettemeister, J. and Klaucke, S.C. and Lacour, P. and Blaschke, F. and Kruse, J. and Parwani, A. and Boldt, L.H. and Bullinger, L. and Pieske, B.M. and Heinzel, F.R. and Hohendanner, F.
PLoS ONE 16 (8): e0255976. 19 August 2021

Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data.
Dimchev, G. and Amiri, B. and Fäßler, F. and Falcke, M. and Schur, F.K.M.
Journal of Structural Biology 213 (4): 107808. December 2021

Characterization of an ester-based core-multishell (CMS) nanocarrier for the topical application at the oral mucosa.
Dommisch, H. and Stolte, K.N. and Jager, J. and Vogel, K. and Müller, R. and Hedtrich, S. and Unbehauen, M. and Haag, R. and Danker, K.
Clinical Oral Investigations 25 (10): 5795-5805. October 2021

Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.
Dorel, M. and Klinger, B. and Mari, T. and Toedling, J. and Blanc, E. and Messerschmidt, C. and Nadler-Holly, M. and Ziehm, M. and Sieber, A. and Hertwig, F. and Beule, D. and Eggert, A. and Schulte, J.H. and Selbach, M. and Blüthgen, N.
PLoS Computational Biology 17 (11): e1009515. 4 November 2021

Modeling Structure-Activity Relationship of AMPK Activation.
Drewe, J. and Küsters, E. and Hammann, F. and Kreuter, M. and Boss, P. and Schöning, V.
Molecules 26 (21): 6508. 1 November 2021

Satralizumab in the treatment of neuromyelitis optica spectrum disorder.
Duchow, A. and Bellmann-Strobl, J.
Neurodegenerative Disease Management 11 (1): 49-59. February 2021

Generation of Epstein-Barr virus antigen-specific T cell receptors recognizing immunodominant epitopes of LMP1, LMP2A, and EBNA3C for immunotherapy.
Dudaniec, K. and Westendorf, K. and Nössner, E. and Uckert, W.
Human Gene Therapy 32 (17-18): 919-935. 21 September 2021

Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders.
Duncan, A.R. and Polovitskaya, M.M. and Gaitán-Peñas, H. and Bertelli, S. and VanNoy, G.E. and Grant, P.E. and O'Donnell-Luria, A. and Valivullah, Z. and Lovgren, A.K. and England, E.M. and Agolini, E. and Madden, J.A. and Schmitz-Abe, K. and Kritzer, A. and Hawley, P. and Novelli, A. and Alfieri, P. and Colafati, G.S. and Wieczorek, D. and Platzer, K. and Luppe, J. and Koch-Hogrebe, M. and Abou Jamra, R. and Neira-Fresneda, J. and Lehman, A. and Boerkoel, C.F. and Seath, K. and Clarke, L. and van Ierland, Y. and Argilli, E. and Sherr, E.H. and Maiorana, A. and Diel, T. and Hempel, M. and Bierhals, T. and Estévez, R. and Jentsch, T.J. and Pusch, M. and Agrawal, P.B.
American Journal of Human Genetics 108 (8): 1450-1465. 5 August 2021

Evaluation of aggression and fearfulness in domestic dog (Canis familiaris).
Dyjak, M. and Boruta, A. and Adamkiewicz, E. and Walasek, A. and Bury-Burzymski, P. and Lisowski, P.
Animal Science Papers and Reports 39 (4): 407-418. 2021

Long-term follow-up after the application of mesenchymal stromal cells in children and adolescents with steroid-refractory graft-versus-host disease.
Döring, M. and Cabanillas Stanchi, K.M. and Lenglinger, K. and Treuner, C. and Gieseke, F. and Erbacher, A. and Mezger, M. and Vaegler, M. and Schlegel, P.G. and Greil, J. and Bettoni da Cunha Riehm, C. and Faul, C. and Schumm, M. and Lang, P. and Handgretinger, R. and Müller, I.
Stem Cells and Development 30 (5): 234-246. 19 February 2021

Germline mutations including the rare pathogenic variant c.3206delC in the ATM gene cause ataxia teleangiectasia-associated primary central nervous system lymphoma.
Dörr, J.R. and Thorwarth, A. and Mizia-Malarz, A. and Radke, J. and Tietze, A. and Hernáiz-Driever, P. and Horn, D. and Gratopp, A. and Eggert, A. and Deubzer, H.E.
Children 8 (6): 469. June 2021

Haplotype-resolved diverse human genomes and integrated analysis of structural variation.
Ebert, P. and Audano, P. A. and Zhu, Q. and Rodriguez-Martin, B. and Porubsky, D. and Bonder, M.J. and Sulovari, A. and Ebler, J. and Zhou, W. and Serra Mari, R. and Yilmaz, F. and Zhao, X. and Hsieh, P.H. and Lee, J. and Kumar, S. and Lin, J. and Rausch, T. and Chen, Y. and Ren, J. and Santamarina, M. and Höps, W. and Ashraf, H. and Chuang, N.T. and Yang, X. and Munson, K.M. and Lewis, A.P. and Fairley, S. and Tallon, L.J. and Clarke, W.E. and Basile, A.O. and Byrska-Bishop, M. and Corvelo, A. and Evani, U.S. and Lu, T.Y. and Chaisson, M.J.P. and Chen, J. and Li, C. and Brand, H. and Wenger, A.M. and Ghareghani, M. and Harvey, W.T. and Raeder, B. and Hasenfeld, P. and Regier, A.A. and Abel, H.J. and Hall, I.M. and Flicek, P. and Stegle, O. and Gerstein, M.B and Tubio, J.M.C. and Mu, Z. and Li, Y.I. and Shi, X. and Hastie, A.R. and Ye, K. and Chong, Z. and Sanders, A.D. and Zody, M.C. and Talkowski, M.E. and Mills, R. E. and Devine, S.E. and Lee, C. and Korbel, J.O. and Marschall, T. and Eichler, E.E.
Science 372 (6537): eabf7117. 25 February 2021

A helminth-derived chitinase structurally similar to mammalian chitinase displays immunomodulatory properties in inflammatory lung disease.
Ebner, F. and Lindner, K. and Janek, K. and Niewienda, A. and Malecki, P.H. and Weiss, M.S. and Sutherland, T.E. and Heuser, A. and Kühl, A.A. and Zentek, J. and Hofmann, A. and Hartmann, S.
Journal of Immunology Research 2021 : 234836. 25 November 2021

Cystatin M/E variant causes autosomal dominant keratosis follicularis spinulosa decalvans by dysregulating cathepsins L and V.
Eckl, K.M. and Gruber, R. and Brennan, L. and Marriott, A. and Plank, R. and Moosbrugger-Martinz, V. and Blunder, S. and Schossig, A. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Zschocke, J. and Hennies, H.C. and Schmuth, M.
Frontiers in Genetics 12 : 689940. July 2021

On the preservation of vessel bifurcations during flow-mediated angiogenic remodelling.
Edgar, L.T. and Franco, C.A. and Gerhardt, H. and Bernabeu, M.O.
PLoS Computational Biology 17 (2): e1007715. 4 February 2021

Surface AMP deaminase 2 as a novel regulator modifying extracellular adenine nucleotide metabolism.
Ehlers, L. and Kuppe, A. and Damerau, A. and Wilantri, S. and Kirchner, M. and Mertins, P. and Strehl, C. and Buttgereit, F. and Gaber, T.
FASEB Journal 35 (7): e21684. July 2021

32-channel self-grounded bow-tie transceiver array for cardiac MR at 7.0T.
Eigentler, T.W. and Kuehne, A. and Boehmert, L. and Dietrich, S. and Els, A. and Waiczies, H. and Niendorf, T.
Magnetic Resonance in Medicine 86 (5): 2862-2879. November 2021

ASHLEYS: automated quality control for single-cell Strand-seq data.
Eimer, C. and Sanders, A.D. and Korbel, J.O. and Marschall, T. and Ebert, P.
Bioinformatics 37 (19): 3356-3357. 1 October 2021

Patch individual filter layers in CNNs to harness the spatial homogeneity of neuroimaging data.
Eitel, F. and Albrecht, J.P. and Weygandt, M. and Paul, F. and Ritter, K.
Scientific Reports 11 (1): 24447. 27 December 2021

Homozygous nonsense mutation of WTN10B gene in a Moroccan family with split-hand foot malformation identified by exome sequencing: a case report.
Elalaoui, S.C. and Fejjal, N. and Li, Y. and Thiele, H. and Altmüller, J. and Guaoua, S. and Nürnberg, P. and Wollnik, B. and Sefiani, A. and Ratbi, I.
Pan African Medical Journal 39 : 21. May 2021

Improving target assessment in biomedical research: the GOT-IT recommendations.
Emmerich, C.H. and Gamboa, L.M. and Hofmann, M.C.J. and Bonin-Andresen, M. and Arbach, O. and Schendel, P. and Gerlach, B. and Hempel, K. and Bespalov, A. and Dirnagl, U. and Parnham, M.J.
Nature Reviews Drug Discovery 20 (1): 64-81. January 2021

Complex population dynamics in a spatial microbial ecosystem with Physarum polycephalum.
Epstein, L. and Dubois, Z. and Smith, J. and Lee, Y. and Harrington, K.
Biosystems 208 : 104483. October 2021

Transposable elements and introgression introduce genetic variation in the invasive ant Cardiocondyla obscurior.
Errbii, M. and Keilwagen, J. and Hoff, K.J. and Steffen, R. and Altmüller, J. and Oettler, J. and Schrader, L.
Molecular Ecology 30 (23): 6211-6228. December 2021

Reactive astrocyte nomenclature, definitions, and future directions.
Escartin, C. and Galea, E. and Lakatos, A. and O'Callaghan, J.P. and Petzold, G.C. and Serrano-Pozo, A. and Steinhäuser, C. and Volterra, A. and Carmignoto, G. and Agarwal, A. and Allen, N.J. and Araque, A. and Barbeito, L. and Barzilai, A. and Bergles, D.E. and Bonvento, G. and Butt, A.M. and Chen, W.T. and Cohen-Salmon, M. and Cunningham, C. and Deneen, B. and De Strooper, B. and Díaz-Castro, B. and Farina, C. and Freeman, M. and Gallo, V. and Goldman, J.E. and Goldman, S.A. and Götz, M. and Gutiérrez, A. and Haydon, P.G. and Heiland, D.H. and Hol, E.M. and Holt, M.G. and Iino, M. and Kastanenka, K.V. and Kettenmann, H. and Khakh, B.S. and Koizumi, S. and Lee, C.J. and Liddelow, S.A. and MacVicar, B.A. and Magistretti, P. and Messing, A. and Mishra, A. and Molofsky, A.V. and Murai, K.K. and Norris, C.M. and Okada, S. and Oliet, S.H.R. and Oliveira, J.F. and Panatier, A. and Parpura, V. and Pekna, M. and Pekny, M. and Pellerin, L. and Perea, G. and Pérez-Nievas, B.G. and Pfrieger, F.W. and Poskanzer, K.E. and Quintana, F.J. and Ransohoff, R.M. and Riquelme-Perez, M. and Robel, S. and Rose, C.R. and Rothstein, J.D. and Rouach, N. and Rowitch, D.H. and Semyanov, A. and Sirko, S. and Sontheimer, H. and Swanson, R.A. and Vitorica, J. and Wanner, I.B. and Wood, L.B. and Wu, J. and Zheng, B. and Zimmer, E.R. and Zorec, R. and Sofroniew, M.V. and Verkhratsky, A.
Nature Neuroscience 24 (3): 312-325. March 2021

Base editing repairs an SGCA mutation in human primary muscle stem cells.
Escobar, H. and Krause, A. and Keiper, S. and Kieshauer, J. and Müthel, S. and García de Paredes, M. and Metzler, E. and Kühn, R. and Heyd, F. and Spuler, S.
JCI Insight 6 (10): e145994. 24 May 2021

Expanding the spectrum of FAT1 nephropathies by novel mutations that affect hippo signaling.
Fabretti, F. and Tschernoster, N. and Erger, F. and Hedergott, A. and Buescher, A.K. and Dafinger, C. and Reusch, B. and Köntges, V.K. and Kohl, S. and Bartram, M.P. and Weber, L.T. and Thiele, H. and Altmueller, J. and Schermer, B. and Beck, B.B. and Habbig, S.
Kidney International Reports 6 (5): 1368-1378. May 2021

Single synapse glutamate imaging reveals multiple levels of release mode regulation in mammalian synapses.
Farsi, Z. and Walde, M. and Klementowicz, A.E. and Paraskevopoulou, F. and Woehler, A.
iScience 24 (1): 101909. 22 January 2021

Galectin-levels are elevated in infants born preterm due to amniotic infection and rapidly decline in the neonatal period.
Faust, K. and Freitag, N. and Barrientos, G. and Hartel, C. and Blois, S.M.
Frontiers in Immunology 11 : 599104. 25 February 2021

Contribution of IQ in young adulthood to the associations of education and occupation with cognitive ability in older age.
Feinkohl, I. and Kozma, P. and Borchers, F. and van Montfort, S.J.T. and Kruppa, J. and Winterer, G. and Spies, C. and Pischon, T.
BMC Geriatrics 21 (1): 346. 5 June 2021

MTBP phosphorylation controls DNA replication origin firing.
Ferreira, P. and Höfer, V. and Kronshage, N. and Marko, A. and Reusswig, K.U. and Tetik, B. and Dießel, C. and Köhler, K. and Tschernoster, N. and Altmüller, J. and Schulze, N. and Pfander, B. and Boos, D.
Scientific Reports 11 (1): 4242. 19 February 2021

The (pro)renin receptor (ATP6ap2) facilitates receptor-mediated endocytosis and lysosomal function in the renal proximal tubule.
Figueiredo, M. and Daryadel, A. and Sihn, G. and Müller, D.N. and Popova, E. and Rouselle, A. and Nguyen, G. and Bader, M. and Wagner, C.A.
Pflugers Archiv 473 : 1229-1246. August 2021

Comparison of the Hi-C, GAM and SPRITE methods using polymer models of chromatin.
Fiorillo, L. and Musella, F. and Conte, M. and Kempfer, R. and Chiariello, A.M. and Bianco, S. and Kukalev, A. and Irastorza-Azcarate, I. and Esposito, A. and Abraham, A. and Prisco, A. and Pombo, A. and Nicodemi, M.
Nature Methods 18 (5): 482-490. May 2021

NFDI4Health - Nationale Forschungsdateninfrastruktur für personenbezogene Gesundheitsdaten.
Fluck, J. and Lindstädt, B. and Ahrens, W. and Beyan, O. and Buchner, B. and Darms, J. and Depping, R. and Dierkes, J. and Fröhlich, H. and Gehrke, J. and Golebiewski, M. and Grabenhenrich, L. and Hahn, H.K. and Kirsten, T. and Klammt, S. and Kusch, H. and Löbe, M. and Löffler, M. and Meineke, F. and Müller, W. and Neuhausen, H. and Nöthlings, U. and Pischon, T. and Prasser, F. and Sax, U. and Schmidt, C.O. and Schulze, M. and Semler, S.C. and Thun, S. and Waltemath, D. and Wieler, L.H. and Zeeb, H. and Pigeot, I.
Bausteine Forschungsdatenmanagement 2021 (2): 72-85. 28 July 2021

An autochthonous mouse model of Myd88- and BCL2-driven diffuse large B-cell lymphoma reveals actionable molecular vulnerabilities.
Flümann, R. and Rehkämper, T. and Nieper, P. and Pfeiffer, P. and Holzem, A. and Klein, S. and Bhatia, S. and Kochanek, M. and Kisis, I. and Pelzer, B.W. and Ahlert, H. and Hauer, J. and da Palma Guerreiro, A. and Ryan, J.A. and Reimann, M. and Riabinska, A. and Wiederstein, J. and Krüger, M. and Deckert, M. and Altmüller, J. and Klatt, A.R. and Frenzel, L.P. and Pasqualucci, L. and Béguelin, W. and Melnick, A.M. and Sander, S. and Montesinos-Rongen, M. and Brunn, A. and Lohneis, P. and Büttner, R. and Kashkar, H. and Borkhardt, A. and Letai, A. and Persigehl, T. and Peifer, M. and Schmitt, C.A. and Reinhardt, H.C. and Knittel, G.
Blood Cancer Discovery 2 (1): 70-91. January 2021

Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations.
Fomin, A. and Gärtner, A. and Cyganek, L. and Tiburcy, M. and Tuleta, I. and Wellers, L. and Folsche, L. and Hobbach, A.J. and von Frieling-Salewsky, M. and Unger, A. and Hucke, A. and Koser, F. and Kassner, A. and Sielemann, K. and Streckfuß-Bömeke, K. and Hasenfuss, G. and Goedel, A. and Laugwitz, K.L. and Moretti, A. and Gummert, J.F. and Dos Remedios, C.G. and Reinecke, H. and Knöll, R. and van Heesch, S. and Hubner, N. and Zimmermann, W.H. and Milting, H. and Linke, W.A.
Science Translational Medicine 13 (618): eabd3079. 3 November 2021

The SEQC2 epigenomics quality control (EpiQC) study.
Foox, J. and Nordlund, J. and Lalancette, C. and Gong, T. and Lacey, M. and Lent, S. and Langhorst, B.W. and Ponnaluri, V.K.C. and Williams, L. and Padmanabhan, K.R. and Cavalcante, R. and Lundmark, A. and Butler, D. and Mozsary, C. and Gurvitch, J. and Greally, J.M. and Suzuki, M. and Menor, M. and Nasu, M. and Alonso, A. and Sheridan, C. and Scherer, A. and Bruinsma, S. and Golda, G. and Muszynska, A. and Łabaj, P.P. and Campbell, M.A. and Wos, F. and Raine, A. and Liljedahl, U. and Axelsson, T. and Wang, C. and Chen, Z. and Yang, Z. and Li, J. and Yang, X. and Wang, H. and Melnick, A. and Guo, S. and Blume, A. and Franke, V. and Ibanez de Caceres, I. and Rodriguez-Antolin, C. and Rosas, R. and Davis, J.W. and Ishii, J. and Megherbi, D.B. and Xiao, W. and Liao, W. and Xu, J. and Hong, H. and Ning, B. and Tong, W. and Akalin, A. and Wang, Y. and Deng, Y. and Mason, C.E.
Genome Biology 22 (1): 332. 6 December 2021

Combinatorial, additive and dose-dependent drug-microbiome associations.
Forslund, S.K. and Chakaroun, R. and Zimmermann-Kogadeeva, M. and Markó, L. and Aron-Wisnewsky, J. and Nielsen, T. and Moitinho-Silva, L. and Schmidt, T.S.B. and Falony, G. and Vieira-Silva, S. and Adriouch, S. and Alves, R.J. and Assmann, K. and Bastard, J.P. and Birkner, T. and Caesar, R. and Chilloux, J. and Coelho, L.P. and Fezeu, L. and Galleron, N. and Helft, G. and Isnard, R. and Ji, B. and Kuhn, M. and Le Chatelier, E. and Myridakis, A. and Olsson, L. and Pons, N. and Prifti, E. and Quinquis, B. and Roume, H. and Salem, J.E. and Sokolovska, N. and Tremaroli, V. and Valles-Colomer, M. and Lewinter, C. and Søndertoft, N.B. and Pedersen, H.K. and Hansen, T.H. and Gøtze, J.P. and Køber, L. and Vestergaard, H. and Hansen, T. and Zucker, J.D. and Hercberg, S. and Oppert, J.M. and Letunic, I. and Nielsen, J. and Bäckhed, F. and Ehrlich, S.D. and Dumas, M.E. and Raes, J. and Pedersen, O. and Clément, K. and Stumvoll, M. and Bork, P.
Nature 600 : 500-505. 16 December 2021

Characteristics of secondary progressive multiple sclerosis: disease activity and provision of care in Germany - a registry-based/multicentric cohort study.
Frahm, N. and Ellenberger, D. and Fneish, F. and Christoph, K. and Warnke, C. and Zettl, U.K. and Paul, F. and Rauser, B. and Stahmann, A. and Vogelmann, V. and Flachenecker, P.
Multiple Sclerosis and Related Disorders 56 : 103281. November 2021

CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression.
Franke, M. and De la Calle-Mustienes, E. and Neto, A. and Almuedo-Castillo, M. and Irastorza-Azcarate, I. and Acemel, R.D. and Tena, J.J. and Santos-Pereira, J.M. and Gómez-Skarmeta, J.L.
Nature Communications 12 (1): 5415. 13 September 2021

Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.
Franken, G.A.C. and Seker, M. and Bos, C. and Siemons, L.A.H. and van der Eerden, B.C.J. and Christ, A. and Hoenderop, J.G.J. and Bindels, R.J.M. and Müller, D. and Breiderhoff, T. and de Baaij, J.H.F.
Scientific Reports 11 (1): 8217. 15 April 2021

Molecular response to PARP1 inhibition in ovarian cancer cells as determined by mass spectrometry based proteomics.
Franz, A. and Coscia, F. and Shen, C. and Charaoui, L. and Mann, M. and Sander, C.
Journal of Ovarian Research 14 (1): 140. 22 October 2021

Overcoming barriers to the adoption of locating technologies in dementia care: a multi-stakeholder focus group study.
Freiesleben, S.D. and Megges, H. and Herrmann, C. and Wessel, L. and Peters, O.
BMC Geriatrics 21 (1): 378. 21 June 2021

Expression of the alternative splicing regulator Rbfox2 during placental development is differentially regulated in preeclampsia mouse models.
Freitag, N. and Xie, Y. and Adam, L.M. and Borowski, S. and Blois, S.M. and Barrientos, G.
American Journal of Reproductive Immunology 86 (6): e13491. December 2021

Dissecting herpes simplex virus 1-induced host shutoff at the RNA level.
Friedel, C.C. and Whisnant, A.W. and Djakovic, L. and Rutkowski, A.J. and Friedl, M.S. and Kluge, M. and Williamson, J.C. and Sai, S. and Vidal, R.O. and Sauer, S. and Hennig, T. and Grothey, A. and Milić, A. and Prusty, B.K. and Lehner, P.J. and Matheson, N.J. and Erhard, F. and Dölken, L.
Journal of Virology 95 (3): e01399-20. 13 January 2021

Stochastic reaction-diffusion modeling of calcium dynamics in 3D-dendritic spines of purkinje cells.
Friedhoff, V.N. and Antunes, G. and Falcke, M. and Simões de Souza, F.M.
Biophysical Journal 120 (11): 2112-2123. 1 June 2021

Models of stochastic Ca(2+) spiking : established approaches and inspirations from models of neuronal spikes.
Friedhoff, V.N. and Ramlow, L. and Lindner, B. and Falcke, M.
European Physical Journal Special Topics 230 (16-17): 2911-2928. October 2021

Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories.
Friedrich, C. and Schallenberg, S. and Kirchner, M. and Ziehm, M. and Niquet, S. and Haji, M. and Beier, C. and Neudecker, J. and Klauschen, F. and Mertins, P.
Nature Communications 12 (1): 3576. 11 June 2021

Resting energy expenditure of master athletes: accuracy of predictive equations and primary determinants.
Frings-Meuthen, P. and Henkel, S. and Boschmann, M. and Chilibeck, P.D. and Alvero Cruz, J.R. and Hoffmann, F. and Möstl, S. and Mittag, U. and Mulder, E. and Rittweger, N. and Sies, W. and Tanaka, H. and Rittweger, J.
Frontiers in Physiology 12 : 641455. 22 March 2021

Optimized workflow for on-line derivatization for targeted metabolomics approach by gas chromatography-mass spectrometry.
Fritsche-Guenther, R. and Gloaguen, Y. and Bauer, A. and Opialla, T. and Kempa, S. and Fleming, C.A. and Redmond, H.P. and Kirwan, J.A.
Metabolites 11 (12): 888. 18 December 2021

Estimation of C. elegans cell- and tissue volumes.
Froehlich, J.J. and Rajewsky, N. and Ewald, C.Y.
microPublication Biology : 000345. 4 January 2021

Parallel genetics of regulatory sequences using scalable genome editing in vivo.
Froehlich, J.J. and Uyar, B. and Herzog, M. and Theil, K. and Glažar, P. and Akalin, A. and Rajewsky, N.
Cell Reports 35 (2): 108988. 13 April 2021

RNA-binding proteins regulate aldosterone homeostasis in human steroidogenic cells.
Fu, R. and Wellman, K. and Baldwin, A. and Rege, J. and Walters, K. and Hirsekorn, A. and Riemondy, K. and Rainey, W.E and Mukherjee, N.
RNA 27 (8): 933-945. August 2021

Use of cement suspension as an alternative matrix material for textile-reinforced concrete.
Fürst, R. and Fürst, E. and Vlach, T. and Řepka, J. and Pokorný, M. and Mózer, V.
Materials 14 (9): 2127. 1 May 2021

Human brain organoids assemble functionally integrated bilateral optic vesicles.
Gabriel, E. and Albanna, W. and Pasquini, Gi. and Ramani, A. and Josipovic, N. and Mariappan, A. and Schinzel, F. and Karch, C.M. and Bao, G. and Gottardo, M. and Suren, A.A. and Hescheler, J. and Nagel-Wolfrum, K. and Persico, V. and Rizzoli, S.O. and Altmüller, J. and Riparbelli, M.G. and Callaini, G. and Goureau, O. and Papantonis, A. and Busskamp, V. and Schneider, T. and Gopalakrishnan, J.
Cell Stem Cell 28 (10): 1740-1757.e8. October 2021

Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects.
Galgoczi, S. and Ruzo, A. and Markopoulos, C. and Yoney, A. and Phan-Everson, T. and Li, S. and Haremaki, T. and Metzger, J.J. and Etoc, F. and Brivanlou, A.H.
Development 148 (19): dev199513. October 2021

Challenges in cell transplantation for muscular dystrophy.
Galli, F. and Mouly, V. and Butler-Browne, G. and Cossu, G.
Experimental Cell Research 409 (1): 112908. 1 December 2021

The polygonal cell shape and surface protein layer of anaerobic methane-oxidizing (methylomirabilis lanthanidiphila) bacteria.
Gambelli, L. and Mesman, R. and Versantvoort, W. and Diebolder, C.A. and Engel, A. and Evers, W. and Jetten, M.S.M. and Pabst, M. and Daum, B. and van Niftrik, L.
Frontiers in Microbiology 12 : 766527. 1 December 2021

Landscape of HER2-low metastatic breast cancer (MBC): results from the Austrian AGMT_MBC-Registry.
Gampenrieder, S.P. and Rinnerthaler, G. and Tinchon, C. and Petzer, A. and Balic, M. and Heibl, S. and Schmitt, C. and Zabernigg, A.F. and Egle, D. and Sandholzer, M. and Singer, C.F. and Roitner, F. and Hager, C. and Andel, J. and Hubalek, M. and Knauer, M. and Greil, R.
Breast Cancer Research 23 (1): 112. 14 December 2021

Reduced mitochondrial respiration in T cells of patients with major depressive disorder.
Gamradt, S. and Hasselmann, H. and Taenzer, A. and Brasanac, J. and Stiglbauer, V. and Sattler, A. and Sajitz-Hermstein, M. and Kierszniowska, S. and Ramien, C. and Nowacki, J. and Mascarell-Maricic, L. and Wingenfeld, K. and Piber, D. and Ströhle, A. and Kotsch, K. and Paul, F. and Otte, C. and Gold, S.M.
iScience 24 (11): 103312. 19 November 2021

Intellectual disability associated with craniofacial dysmorphism, cleft palate, and congenital heart defect due to a de novo MEIS2 mutation: a clinical longitudinal study.
Gangfuß, A. and Yigit, G. and Altmüller, J. and Nürnberg, P. and Czeschik, J.C. and Wollnik, B. and Bögershausen, N. and Burfeind, P. and Wieczorek, D. and Kaiser, F. and Roos, A. and Kölbel, H. and Schara-Schmidt, U. and Kuechler, A.
American Journal of Medical Genetics A 185 (4): 1216-1221. April 2021

Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor.
Ganichkin, O.M. and Vancraenenbroeck, R. and Rosenblum, G. and Hofmann, H. and Mikhailov, A.S. and Daumke, O. and Noel, J.K.
Proceedings of the National Academy of Sciences of the United States of America 118 (28): e2101144118. 13 July 2021

Place fields of single spikes in hippocampus involve Kcnq3 channel-dependent entrainment of complex spike bursts.
Gao, X. and Bender, F. and Soh, H. and Chen, C. and Altafi, M. and Schütze, S. and Heidenreich, M. and Gorbati, M. and Corbu, M.A. and Carus-Cadavieco, M. and Korotkova, T. and Tzingounis, A.V. and Jentsch, T.J. and Ponomarenko, A.
Nature Communications 12 (1): 4801. 10 August 2021

PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Garg, A. and Roske, Y. and Yamada, S. and Uehata, T. and Takeuchi, O. and Heinemann, U.
Nucleic Acids Research 49 (9): 5369-5381. 21 May 2021

SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Gassen, N.C. and Papies, J. and Bajaj, T. and Emanuel, J. and Dethloff, F. and Chua, R.L. and Trimpert, J. and Heinemann, N. and Niemeyer, C. and Weege, F. and Hönzke, K. and Aschman, T. and Heinz, D.E. and Weckmann, K. and Ebert, T. and Zellner, A. and Lennarz, M. and Wyler, E. and Schroeder, S. and Richter, A. and Niemeyer, D. and Hoffmann, K. and Meyer, T.F. and Heppner, F.L. and Corman, V.M. and Landthaler, M. and Hocke, A.C. and Morkel, M. and Osterrieder, N. and Conrad, C. and Eils, R. and Radbruch, H. and Giavalisco, P. and Drosten, C. and Müller, M.A.
Nature Communications 12 (1): 3818. 21 June 2021

Stress CMR in patients with obesity: insights from the Stress CMR Perfusion Imaging in the United States (SPINS) registry.
Ge, Y. and Steel, K. and Antiochos, P. and Bingham, S. and Abdullah, S. and Mikolich, J.R. and Arai, A.E. and Bandettini, W.P. and Shanbhag, S.M. and Patel, A.R. and Farzaneh-Far, A. and Heitner, J.F. and Shenoy, C. and Leung, S.W. and Gonzalez, J.A. and Shah, D.J. and Raman, S.V. and Nawaz, H. and Ferrari, V.A. and Schulz-Menger, J. and Stuber, M. and Simonetti, O.P. and Kwong, R.Y.
European Heart Journal - Cardiovascular Imaging 22 (5): 518-527. May 2021

Recurrent frameshift neoantigen vaccine elicits protective immunity with reduced tumor burden and improved overall survival in a Lynch syndrome mouse model.
Gebert, J. and Gelincik, O. and Oezcan-Wahlbrink, M. and Marshall, J.D. and Hernandez-Sanchez, A. and Urban, K. and Long, M. and Cortes, E. and Tosti, E. and Katzenmaier, E.M. and Song, Y. and Elsaadi, A. and Deng, N. and Vilar, E. and Fuchs, V. and Nelius, N. and Yuan, Y.P. and Ahadova, A. and Sei, S. and Shoemaker, R.H. and Umar, A. and Wei, L. and Liu, S. and Bork, P. and Edelmann, W. and von Knebel Doeberitz, M. and Lipkin, S.M. and Kloor, M.
Gastroenterology 161 (4): 288-1302.e13. October 2021

Identifying cell-type-specific metabolic signatures using transcriptome and proteome analyses.
Gebert, N. and Rahman, S. and Lewis, C.A. and Ori, A. and Cheng, C.W.
Current Protocols 1 (9): e245. 28 September 2021

Salt transiently inhibits mitochondrial energetics in mononuclear phagocytes.
Geisberger, S. and Bartolomaeus, H. and Neubert, P. and Willebrand, R. and Zasada, C. and Bartolomaeus, T. and McParland, V. and Swinnen, D. and Geuzens, A. and Maifeld, A. and Krampert, L. and Vogl, M. and Mähler, A. and Wilck, N. and Marko, L. and Tilic, E. and Forslund, S.K. and Binger, K.J. and Stegbauer, J. and Dechend, R. and Kleinewietfeld, M. and Jantsch, J. and Kempa, S. and Müller, D.N.
Circulation 144 (2): 144-158. 13 July 2021

Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development.
Geusz, R.J. and Wang, A. and Chiou, J. and Lancman, J.J. and Wetton, N. and Kefalopoulou, S. and Wang, J. and Qiu, Y. and Yan, J. and Aylward, A. and Ren, B. and Dong, P.D.S. and Gaulton, K.J. and Sander, M.
eLife 10 : e59067. 5 February 2021

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.
Geusz, R.J. and Wang, A. and Lam, D.K. and Vinckier, N.K. and Alysandratos, K.D. and Roberts, D.A. and Wang, J. and Kefalopoulou, S. and Ramirez, A. and Qiu, Y. and Chiou, J. and Gaulton, K.J. and Ren, B. and Kotton, D.N. and Sander, M.
Nature Communications 12 (1): 6636. 17 November 2021

DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia.
Giacopelli, B. and Wang, M. and Cleary, A. and Wu, Y.Z. and Schultz, A.R. and Schmutz, M. and Blachly, J.S. and Eisfeld, A.K. and Mundy-Bosse, B. and Vosberg, S. and Greif, P.A. and Claus, R. and Bullinger, L. and Garzon, R. and Coombes, K.R. and Bloomfield, C.D. and Druker, B.J. and Tyner, J.W. and Byrd, J.C. and Oakes, C.C.
Genome Research 31 (5): 747-761. May 2021

Alectinib treatment improves photodynamic therapy in cancer cell lines of different origin.
Gillissen, B. and Richter, A. and Essmann, F. and Kemmner, W.
BMC Cancer 21 (1): 971. 30 August 2021

A novel remitting leukodystrophy associated with a variant in FBP2.
Gizak, A. and Diegmann, S. and Dreha-Kulaczewski, S. and Wiśniewski, J. and Duda, P. and Ohlenbusch, A. and Huppke, B. and Henneke, M. and Höhne, W. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Rakus, D. and Gärtner, J. and Huppke, P.
Brain Communications 3 (2): fcab036. 11 March 2021

Reliable kidney size determination by magnetic resonance imaging in pathophysiological settings.
Gladytz, T. and Millward, J.M. and Cantow, K. and Hummel, L. and Zhao, K. and Flemming, B. and Periquito, J.S. and Pohlmann, A. and Waiczies, S. and Seeliger, E. and Niendorf, T.
Acta Physiologica 233 (2): e13701. October 2021

Assessing genome-wide dynamic changes in enhancer activity during early mESC differentiation by FAIRE-STARR-seq.
Glaser, L.V. and Steiger, M. and Fuchs, A. and van Bömmel, A. and Einfeldt, E. and Chung, H.R. and Vingron, M. and Meijsing, S.H.
Nucleic Acids Research 49 (21): 12178-12195. 2 December 2021

NEPHRO-ZEBRA-acute troponin increase in a kidney transplant recipient - the unknown knowns?
Goerlich, N. and Klingel, K. and Stangl, K. and Gaedeke, J. and Eckardt, K.U. and Kettritz, R.
Journal of Nephrology 34 (3): 931-933. June 2021

Mitigated viral myocarditis in A/J mice by the immunoproteasome inhibitor ONX 0914 depends on inhibition of systemic inflammatory responses in CoxsackievirusB3 infection.
Goetzke, C.C. and Althof, N. and Neumaier, H.L. and Heuser, A. and Kaya, Z. and Kespohl, M. and Klingel, K. and Beling, A.
Basic Research in Cardiology 116 (1): 7. 1 February 2021

Caution, "normal" BMI: health risks associated with potentially masked individual underweight - EPMA position paper 2021.
Golubnitschaja, O. and Liskova, A. and Koklesova, L. and Samec, M. and Biringer, K. and Büsselberg, D. and Podbielska, H. and Kunin, A.A. and Evsevyeva, M.E. and Shapira, N. and Paul, F. and Erb, C. and Dietrich, D.E. and Felbel, D. and Karabatsiakis, A. and Bubnov, R. and Polivka, J. and Polivka, J.J. and Birkenbihl, C. and Fröhlich, H. and Hofmann-Apitius, M. and Kubatka, P.
EPMA Journal 12 (3): 243-264. September 2021

The zinc finger antiviral protein ZAP restricts human cytomegalovirus and selectively binds and destabilizes viral UL4/UL5 transcripts.
Gonzalez-Perez, A.C. and Stempel, M. and Wyler, E. and Urban, C. and Piras, A. and Hennig, T. and Ganskih, S. and Wei, Y. and Heim, A. and Landthaler, M. and Pichlmair, A. and Dölken, L. and Munschauer, M. and Erhard, F. and Brinkmann, M.M.
mBio 12 (3): e02683-20. 4 May 2021

MLL1 is required for maintenance of intestinal stem cells.
Goveas, N. and Waskow, C. and Arndt, K. and Heuberger, J. and Zhang, Q. and Alexopoulou, D. and Dahl, A. and Birchmeier, W. and Anastassiadis, K. and Stewart, A.F. and Kranz, A.
PLoS Genetics 17 (12): e1009250. 3 December 2021

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network.
Grapotte, M. and Saraswat, M. and Bessière, C. and Menichelli, C. and Ramilowski, J.A. and Severin, J. and Hayashizaki, Y. and Itoh, M. and Tagami, M. and Murata, M. and Kojima-Ishiyama, M. and Noma, S. and Noguchi, S. and Kasukawa, T. and Hasegawa, A. and Suzuki, H. and Nishiyori-Sueki, H. and Frith, M.C. and Chatelain, C. and Carninci, P. and de Hoon, M.J.L. and Wasserman, W.W. and Bréhélin, L. and Lecellier, C.H.
Nature Communications 12 (1): 3297. 2 June 2021

Survivin’ acute myeloid leukaemia - a personalised target for inv(16) patients.
Greiner, J. and Brown, E. and Bullinger, L. and Hills, R.K. and Morris, V. and Döhner, H. and Mills, K.I. and Guinn, B.A.
International Journal of Molecular Sciences 22 (19): 10482. 1 October 2021

Transcriptome of iPSC-derived neuronal cells reveals a module of co-expressed genes consistently associated with autism spectrum disorder.
Griesi-Oliveira, K. and Fogo, M.S. and Pinto, B.G.G. and Alves, A.Y. and Suzuki, A.M. and Morales, A.G. and Ezquina, S. and Sosa, O.J. and Sutton, G.J. and Sunaga-Franze, D.Y. and Bueno, A.P. and Seabra, G. and Sardinha, L. and Costa, S.S. and Rosenberg, C. and Zachi, E.C. and Sertie, A.L. and Martins-de-Souza, D. and Reis, E.M. and Voineagu, I. and Passos-Bueno, M.R.
Molecular Psychiatry 26 (5): 1589-1605. May 2021

Development of SARA(home), a new video-based tool for the assessment of ataxia at home.
Grobe-Einsler, M. and Taheri Amin, A. and Faber, J. and Schaprian, T. and Jacobi, H. and Schmitz-Hübsch, T. and Diallo, A. and Tezenas du Montcel, S. and Klockgether, T.
Movement Disorders 36 (5): 1242-1246. May 2021

Neurochemical differences in spinocerebellar ataxia type 14 and 1.
Grosch, A.S. and Rinnenthal, J.L. and Rönnefarth, M. and Lux, S. and Scheel, M. and Endres, M. and Brandt, A.U. and Paul, F. and Schmitz-Hübsch, T. and Minnerop, M. and Doss, S.
Cerebellum 20 (2): 169-178. April 2021

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4.
Grosche, S. and Marenholz, I. and Esparza-Gordillo, J. and Arnau-Soler, A. and Pairo-Castineira, E. and Rüschendorf, F. and Ahluwalia, T.S. and Almqvist, C. and Arnold, A. and Baurecht, H. and Bisgaard, H. and Bønnelykke, K. and Brown, S.J. and Bustamante, M. and Curtin, J.A. and Custovic, A. and Dharmage, S.C. and Esplugues, A. and Falchi, M. and Fernandez-Orth, D. and Ferreira, M.A.R. and Franke, A. and Gerdes, S. and Gieger, C. and Hakonarson, H. and Holt, P.G. and Homuth, G. and Hubner, N. and Hysi, P.G. and Jarvelin, M.R. and Karlsson, R. and Koppelman, G.H. and Lau, S. and Lutz, M. and Magnusson, P.K.E. and Marks, G.B. and Müller-Nurasyid, M. and Nöthen, M.M. and Paternoster, L. and Pennell, C.E. and Peters, A. and Rawlik, K. and Robertson, C.F. and Rodriguez, E. and Sebert, S. and Simpson, A. and Sleiman, P.M.A. and Standl, M. and Stölzl, D. and Strauch, K. and Szwajda, A. and Tenesa, A. and Thompson, P.J. and Ullemar, V. and Visconti, A. and Vonk, J.M. and Wang, C.A. and Weidinger, S. and Wielscher, M. and Sargent, C.L. and Xu, C.J. and Lee, Y.A.
Nature Communications 12 (1): 6618. 16 November 2021

Parvalbumin interneurons are differentially connected to principal cells in inhibitory feedback microcircuits along the dorsoventral axis of the medial entorhinal cortex.
Grosser, S. and Barreda, F.J. and Beed, P. and Schmitz, D. and Booker, S.A. and Vida, I.
eNeuro 8 (1): ENEURO.0354-20.2020. 2 February 2021

A reproducible bioprinted 3D tumor model serves as a preselection tool for CAR T cell therapy optimization.
Grunewald, L. and Lam, T. and Andersch, L. and Klaus, A. and Schwiebert, S. and Winkler, A. and Gauert, A. and Heeren-Hagemann, A.I. and Astrahantseff, K. and Klironomos, F. and Thomas, A. and Deubzer, H.E. and Henssen, A.G. and Eggert, A. and Schulte, J.H. and Anders, K. and Kloke, L. and Künkele, A.
Frontiers in Immunology 12 : 689697. 29 June 2021

How to find genomic regions relevant for gene regulation.
Guo, X. and Ohler, U. and Yildirim, F.
Medizinische Genetik 33 (2): 157-165. 14 August 2021

Acute kidney injury in patients treated with immune checkpoint inhibitors.
Gupta, S. and Short, S.A.P. and Sise, M.E. and Prosek, J.M. and Madhavan, S.M. and Soler, M.J. and Ostermann, M. and Herrmann, S.M. and Abudayyeh, A. and Anand, S. and Glezerman, I. and Motwani, S.S. and Murakami, N. and Wanchoo, R. and Ortiz-Melo, D.I. and Rashidi, A. and Sprangers, B. and Aggarwal, V. and Malik, A.B. and Loew, S. and Carlos, C.A. and Chang, W.T. and Beckerman, P. and Mithani, Z. and Shah, C.V. and Renaghan, A.D. and Seigneux, S.D. and Campedel, L. and Kitchlu, A. and Shin, D.S. and Rangarajan, S. and Deshpande, P. and Coppock, G. and Eijgelsheim, M. and Seethapathy, H. and Lee, M.D. and Strohbehn, I.A. and Owen, D.H. and Husain, M. and Garcia-Carro, C. and Bermejo, S. and Lumlertgul, N. and Seylanova, N. and Flanders, L. and Isik, B. and Mamlouk, O. and Lin, J.S. and Garcia, P. and Kaghazchi, A. and Khanin, Y. and Kansal, S.K. and Wauters, E. and Chandra, S. and Schmidt-Ott, K.M. and Hsu, R.K. and Tio, M.C. and Sarvode Mothi, S. and Singh, H. and Schrag, D. and Jhaveri, K.D. and Reynolds, K.L. and Cortazar, F.B. and Leaf, D.E.
Journal for ImmunoTherapy of Cancer 9 (10): e003467. October 2021

OGEE v3: Online GEne Essentiality database with increased coverage of organisms and human cell lines.
Gurumayum, S. and Jiang, P. and Hao, X. and Campos, T.L. and Young, N.D. and Korhonen, P.K. and Gasser, R.B. and Bork, P. and Zhao, X.M. and He, L.J. and Chen, W.H.
Nucleic Acids Research 49 (D1): D998-D1003. 8 January 2021

CRISPRi screens reveal genes modulating yeast growth in lignocellulose hydrolysate.
Gutmann, F. and Jann, C. and Pereira, F. and Johansson, A. and Steinmetz, L.M. and Patil, K.R.
Biotechnology for Biofuels 14 (1): 41. 10 February 2021

Cellular basis of ClC-2 Cl(-) channel-related brain and testis pathologies.
Göppner, C. and Soria, A.H. and Hoegg-Beiler, M.B. and Jentsch, T.J.
Journal of Biological Chemistry 296 : 100074. 4 January 2021

Bionic tracking: using eye tracking to track biological cells in virtual reality.
Günther, U. and Harrington, K.I.S. and Dachselt, R. and Sbalzarini, I.F.
Lecture Notes in Computer Science 12535 : 280-297. 2021

Energy metabolites as biomarkers in ischemic and dilated cardiomyopathy.
Haas, J. and Frese, K.S. and Sedaghat-Hamedani, F. and Kayvanpour, E. and Tappu, R. and Nietsch, R. and Tugrul, O.F. and Wisdom, M. and Dietrich, C. and Amr, A. and Weis, T. and Niederdränk, T. and Murphy, M.P. and Krieg, T. and Dörr, M. and Völker, U. and Fielitz, J. and Frey, N. and Felix, S.B. and Keller, A. and Katus, H.A. and Meder, B.
International Journal of Molecular Sciences 22 (4): 1999. 18 February 2021

Propionic acid rescues high-fat diet enhanced immunopathology in autoimmunity via effects on Th17 responses.
Haase, S. and Mäurer, J. and Duscha, A. and Lee, D.H. and Balogh, A. and Gold, R. and Müller, D.N. and Haghikia, A. and Linker, R.A.
Frontiers in Immunology 12 : 701626. 1 June 2021

A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3.
Halatsch, M.E. and Kast, R.E. and Karpel-Massler, G. and Mayer, B. and Zolk, O. and Schmitz, B. and Scheuerle, A. and Maier, L. and Bullinger, L. and Mayer-Steinacker, R. and Schmidt, C. and Zeiler, K. and Elshaer, Z. and Panther, P. and Schmelzle, B. and Hallmen, A. and Dwucet, A. and Siegelin, M.D. and Westhoff, M.A. and Beckers, K. and Bouche, G. and Heiland, T.
Neuro-Oncology Advances 3 (1): vdab075. 7 August 2021

Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice.
Hammer, K.P. and Mustroph, J. and Stauber, T. and Birchmeier, W. and Wagner, S. and Maier, L.S.
PLoS ONE 16 (6): e0252649. 4 June 2021

Multi-channel RF supervision module for thermal magnetic resonance based cancer therapy.
Han, H. and Oberacker, E. and Kuehne, A. and Wang, S. and Eigentler, T.W. and Grass, E. and Niendorf, T.
Cancers 13 (5): 1001. 28 February 2021

Critical illness and systemic inflammation are key risk factors of severe acute kidney injury in patients with COVID-19.
Hardenberg, J.H.B. and Stockmann, H. and Aigner, A. and Gotthardt, I. and Enghard, P. and Hinze, C. and Balzer, F. and Schmidt, D. and Zickler, D. and Kruse, J. and Körner, R. and Stegemann, M. and Schneider, T. and Schumann, M. and Müller-Redetzky, H. and Angermair, S. and Budde, K. and Weber-Carstens, S. and Witzenrath, M. and Treskatsch, S. and Siegmund, B. and Spies, C. and Suttorp, N. and Rauch, G. and Eckardt, K.U. and Schmidt-Ott, K.M.
Kidney International Reports 6 (4): 905-915. April 2021

Genome-wide analysis of actively translated open reading frames using riboTaper/ORFquant.
Harnett, D. and Meerdink, E. and Calviello, L. and Sydow, D. and Ohler, U.
Methods in Molecular Biology 2252 : 331-346. 2021

Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity.
Harper, A.R. and Goel, A. and Grace, C. and Thomson, K.L. and Petersen, S.E. and Xu, X. and Waring, A. and Ormondroyd, E. and Kramer, C.M. and Ho, C.Y. and Neubauer, S. and Tadros, R. and Ware, J.S. and Bezzina, C.R. and Farrall, M. and Watkins, H.
Nature Genetics 53 (2): 135-142. February 2021

Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Hartlieb, S.A. and Sieverling, L. and Nadler-Holly, M. and Ziehm, M. and Toprak, U.H. and Herrmann, C. and Ishaque, N. and Okonechnikov, K. and Gartlgruber, M. and Park, Y.G. and Wecht, E.M. and Savelyeva, L. and Henrich, K.O. and Rosswog, C. and Fischer, M. and Hero, B. and Jones, D.T.W. and Pfaff, E. and Witt, O. and Pfister, S.M. and Volckmann, Ri. and Koster, J. and Kiesel, K. and Rippe, K. and Taschner-Mandl, S. and Ambros, P. and Brors, B. and Selbach, M. and Feuerbach, L. and Westermann, F.
Nature Communications 12 (1): 1269. 24 February 2021

Delayed access to conscious processing in multiple sclerosis: reduced cortical activation and impaired structural connectivity.
Has Silemek, A.C. and Ranjeva, J.P. and Audoin, B. and Heesen, C. and Gold, S.M. and Kühn, S. and Weygandt, M. and Stellmann, J.P.
Human Brain Mapping 42 (11): 3379-3395. 1 August 2021

Insulin-like growth factor binding protein-2 (IGFBP2) is a key molecule in the MACC1-mediated platelet communication and metastasis of colorectal cancer cells.
Haschemi, R. and Kobelt, D. and Steinwarz, E. and Schlesinger, M. and Stein, U. and Bendas, G.
International Journal of Molecular Sciences 22 (22): 12195. 11 November 2021

Stepwise conformational stabilization of a HIV-1 Clade C consensus envelope trimer immunogen impacts the profile of vaccine-induced antibody responses.
Hauser, A. and Carnell, G. and Held, K. and Sulbaran, G. and Tischbierek, N. and Rogers, L. and Pollakis, G. and Tonks, P. and Hoelscher, M. and Ding, S. and Sanders, R.W. and Geldmacher, C. and Sattentau, Q. and Weissenhorn, W. and Heeney, J.L. and Peterhoff, D. and Wagner, R.
Vaccines 9 (7): 750. 6 July 2021

Artificially produced gametes in mice, humans and other species.
Hayashi, K. and Galli, C. and Diecke, S. and Hildebrandt, T.B.
Reproduction Fertility and Development 33 (2): 91-101. 8 January 2021

CD4+ T cell dependent B cell recovery and function after autologous hematopoietic stem cell transplantation.
Heck, C. and Steiner, S. and Kaebisch, E.M. and Frentsch, M. and Wittenbecher, F. and Scheibenbogen, C. and Hanitsch, L.G. and Nogai, A. and le Coutre, P. and Bullinger, L. and Blau, I.W. and Na, I.K.
Frontiers in Immunology 12 : 736137. September 2021

Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA) extended follow-up of a 2×2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol.
Heck, S.L. and Mecinaj, A. and Ree, A.H. and Hoffmann, P. and Schulz-Menger, J.E. and Fagerland, M.W. and Gravdehaug, B. and Røsjø, H. and Steine, K. and Geisler, J. and Gulati, G. and Omland, T.
Circulation 143 (25): 2431-2440. 22 June 2021

The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
Heider, M. and Eichner, R. and Stroh, J. and Morath, V. and Kuisl, A. and Zecha, J. and Lawatscheck, J. and Baek, K. and Garz, A.K. and Rudelius, M. and Deuschle, F.C. and Keller, U. and Lemeer, S. and Verbeek, M. and Götze, K.S. and Skerra, A. and Weber, W.A. and Buchner, J. and Schulman, B.A. and Kuster, B. and Fernández-Sáiz, V. and Bassermann, F.
Molecular Cell 81 (6): 1170-1186. 18 March 2021

Preoperative comparison of three anticholinergic drug scales in older adult patients and development of postoperative delirium: a prospective observational study.
Heinrich, M. and Müller, A. and Cvijan, A. and Mörgeli, R. and Kruppa, J. and Winterer, G. and Slooter, A.J.C. and Spies, C.D.
Drugs & Aging 38 (4): 347-354. April 2021

Preoperative medication use and development of postoperative delirium and cognitive dysfunction.
Heinrich, M. and Nottbrock, A. and Borchers, F. and Mörgeli, R. and Kruppa, J. and Winterer, G. and Slooter, A.J.C. and Spies, C.
Clinical and Translational Science 14 (5): 1830-1840. September 2021

Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients.
Heinrich, M. and Sieg, M. and Kruppa, J. and Nürnberg, P. and Schreier, P.H. and Heilmann-Heimbach, S. and Hoffmann, P. and Nöthen, M.M. and Janke, J. and Pischon, T. and Slooter, A.J.C. and Winterer, G. and Spies, C.D.
BMC Medical Genomics 14 : 248. 21 October 2021

Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation.
Heller, S. and Li, Z. and Lin, Q. and Geusz, R. and Breunig, M. and Hohwieler, M. and Zhang, X. and Nair, G.G. and Seufferlein, T. and Hebrok, M. and Sander, M. and Julier, C. and Kleger, A. and Costa, I.G.
Communications Biology 4 (1): 1298. 17 November 2021

A comparison of nine machine learning mutagenicity models and their application for predicting pyrrolizidine alkaloids.
Helma, C. and Schöning, V. and Drewe, J. and Boss, P.
Frontiers in Pharmacology 12 : 708050. 22 July 2021

Dual-color fluorescence cross-correlation spectroscopy to study protein-protein interaction and protein dynamics in live cells.
Hemmen, K. and Choudhury, S. and Friedrich, M. and Balkenhol, J. and Knote, F. and Lohse, M.J. and Heinze, K.G.
Journal of Visualized Experiments 178 : e62954. 11 December 2021

Low-fat hypocaloric diet reduces neprilysin in overweight and obese human subjects.
Henke, C. and Haufe, S. and Ziehl, D. and Bornstein, S.R. and Schulz-Menger, J. and Heni, M. and Engeli, S. and Jordan, J. and Birkenfeld, A.L.
ESC Heart Failure 8 (2): 938-942. April 2021

Long-term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges.
Herda, S. and Heimann, A. and Obermayer, B. and Ciraolo, E. and Althoff, S. and Ruß, J. and Grunert, C. and Busse, A. and Bullinger, L. and Pezzutto, A. and Blankenstein, T. and Beule, D. and Na, I.K.
International Journal of Cancer 148 (12): 3097-3110. 15 June 2021

Simultaneous T(2) and T(2)* mapping of multiple sclerosis lesions with radial RARE-EPI.
Herrmann, C. and Els, A. and Boehmert, L. and Periquito, J. and Eigentler, T.W. and Millward, J. and Waiczies, S. and Kuchling, J. and Paul, F. and Niendorf, T.
Magnetic Resonance in Medicine 86 (3): 1383-1402. September 2021

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J. and Grinat, J. and Kosel, F. and Liu, L. and Kunz, S. and Vidal, R.O. and Keil, M. and Haybaeck, J. and Robine, S. and Louvard, D. and Regenbrecht, C. and Sporbert, A. and Sauer, S. and von Eyss, B. and Sigal, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 118 (22): e2019699118. 1 June 2021

Epithelial response to IFN-γ promotes SARS-CoV-2 infection.
Heuberger, J. and Trimpert, J. and Vladimirova, D. and Goosmann, C. and Lin, M. and Schmuck, R. and Mollenkopf, H.J. and Brinkmann, V. and Tacke, F. and Osterrieder, N. and Sigal, M.
EMBO Molecular Medicine 13 (4): e13191. 9 April 2021

Posttransplantation MRD monitoring in patients with AML by next-generation sequencing using DTA and non-DTA mutations.
Heuser, M. and Heida, B. and Büttner, K. and Wienecke, C.P. and Teich, K. and Funke, C. and Brandes, M. and Klement, P. and Liebich, A. and Wichmann, M. and Neziri, B. and Chaturvedi, A. and Kloos, A. and Mintzas, K. and Gaidzik, V.I. and Paschka, P. and Bullinger, L. and Fiedler, W. and Heim, A. and Puppe, W. and Krauter, J. and Döhner, K. and Döhner, H. and Ganser, A. and Stadler, M. and Hambach, L. and Gabdoulline, R. and Thol, F.
Blood Advances 5 (9): 2294-2304. 11 May 2021

Dispersal strategies shape persistence and evolution of human gut bacteria.
Hildebrand, F. and Gossmann, T.I. and Frioux, C. and Özkurt, E. and Myers, P.N. and Ferretti, P. and Kuhn, M. and Bahram, M. and Nielsen, H.B. and Bork, P.
Cell Host & Microbe 29 (7): 1167-1176. 14 June 2021

The ART of bringing extinction to a freeze - history and future of species conservation, exemplified by rhinos.
Hildebrandt, T.B. and Hermes, R. and Goeritz, F. and Appeltant, R. and Colleoni, S. and de Mori, B. and Diecke, S. and Drukker, M. and Galli, C. and Hayashi, K. and Lazzari, G. and Loi, P. and Payne, J. and Renfree, M. and Seet, S. and Stejskal, J. and Swegen, A. and Williams, S.A. and Zainuddin, Z.Z. and Holtze, S.
Theriogenology 169 : 76-88. 15 July 2021

Conservation research in times of COVID-19 - the rescue of the northern white rhino.
Hildebrandt, T.B. and Holtze, S. and Biasetti, P. and Colleoni, S. and de Mori, B. and Diecke, S. and Göritz, F. and Hayashi, K. and Hayashi, M. and Hermes, R. and Kariuki, L. and Lazzari, G. and Mijele, D. and Mutisya, S. and Ndeereh, D. and Ngulu, S. and Seet, S. and Zwilling, J. and Zywitza, V. and Stejskal, J. and Galli, C.
Journal of Applied Animal Ethics Research 3 (1): 16-37. May 2021

Construction of whole genomes from scaffolds using single cell strand-seq data.
Hills, M. and Falconer, E. and O'Neill, K. and Sanders, A.D. and Howe, K. and Guryev, V. and Lansdorp, P.M.
International Journal of Molecular Sciences 22 (7): 3617. 1 April 2021

Kidney single-cell transcriptomes predict spatial corticomedullary gene expression and tissue osmolality gradients.
Hinze, C. and Karaiskos, N. and Boltengagen, A. and Walentin, K. and Redo, K. and Himmerkus, N. and Bleich, M. and Potter, S.S. and Potter, A.S. and Eckardt, K.U. and Kocks, C. and Rajewsky, N. and Schmidt-Ott, K.M.
Journal of the American Society of Nephrology 32 (2): 291-306. February 2021

A public health antibody screening indicates a 6-fold higher SARS-CoV-2 exposure rate than reported cases in children.
Hippich, M. and Holthaus, L. and Assfalg, R. and Zapardiel Gonzalo, J.M. and Kapfelsperger, H. and Heigermoser, M. and Haupt, F. and Ewald, D.A. and Welzhofer, T.C. and Marcus, B.A. and Heck, S. and Koelln, A. and Stock, J. and Voss, F. and Secchi, M. and Piemonti, L. and de la Rosa, K. and Protzer, U. and Boehmer, M. and Achenbach, P. and Lampasona, V. and Bonifacio, E. and Ziegler, A.G.
Med 2 (2): 149-163. 12 February 2021

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.
Ho, J.S. and Di Tullio, F. and Schwarz, M. and Low, D. and Incarnato, D. and Gay, F. and Tabaglio, T. and Zhang, J.X. and Wollmann, H. and Chen, L. and An, O. and Chan, T.H.M. and Hall Hickman, A. and Zheng, S. and Roudko, V. and Chen, S. and Karz, A. and Ahmed, M. and He, H.H. and Greenbaum, B.D. and Oliviero, S. and Serresi, M. and Gargiulo, G. and Mann, K.M. and Hernando, E. and Mulholland, D. and Marazzi, I. and Wee, D.K.B. and Guccione, E.
eLife 10 : e59654. 2 June 2021

Gynecological cancer and omega-3 fatty acid intakes: meta-analysis.
Hoang, T. and Myung, S.K. and Pham, T.T.
Asia Pacific Journal of Clinical Nutrition 30 (1): 153-162. March 2021

Post-myocardial infarction heart failure dysregulates the bone vascular niche.
Hoffmann, J. and Luxán, G. and Abplanalp, W.T. and Glaser, S.F. and Rasper, T. and Fischer, A. and Muhly-Reinholz, M. and Potente, M. and Assmus, B. and John, D. and Zeiher, A.M. and Dimmeler, S.
Nature Communications 12 (1): 3964. 25 June 2021

Sollten Patienten nach überlebter akuter Nierenschädigung mit RAAS-Inhibitoren behandelt werden? [Should patients after surviving acute kidney injury be treated with RAAS inhibitors?].
Hoffmann, L. and Schmidt-Ott, K.M.
Nephrologe 16 (5): 305-306. September 2021

Agonistic autoantibodies against β2-adrenergic receptor influence retinal microcirculation in glaucoma suspects and patients.
Hohberger, B. and Hosari, S. and Wallukat, G. and Kunze, R. and Krebs, J. and Müller, M. and Hennig, T. and Lämmer, R. and Horn, F. and Muñoz, L.E. and Herrmann, M. and Mardin, C.
PLoS ONE 16 (5): e0249202. 7 May 2021

Inhibitory and agonistic autoantibodies directed against the ß(2)-adrenergic receptor in pseudoexfoliation syndrome and glaucoma.
Hohberger, B. and Schlötzer-Schrehard, U. and Mardin, C. and Lämmer, R. and Munoz, L. and Kunze, R. and Herrmann, M. and Wallukat, G.
Frontiers in Neuroscience 15 : 676579. 6 August 2021

Agonistic β2-adrenergic receptor autoantibodies characterize the aqueous humor of patients with primary and secondary open-angle glaucoma.
Hohberger, B. and Wörn, M. and Lämmer, R. and Mahajan, A. and Mardin, C. and Schötzer-Schrehardt, U. and Kunze, R. and Herrmann, M. and Wallukat, G.
Frontiers in Immunology 12 : 550236. 5 May 2021

Spatio-temporal mRNA tracking in the early zebrafish embryo.
Holler, K. and Neuschulz, A. and Drewe-Boß, P. and Mintcheva, J. and Spanjaard, B. and Arsiè, R. and Ohler, U. and Landthaler, M. and Junker, J.P.
Nature Communications 12 : 3358. 7 June 2021

A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: results from the CONKO-005 trial.
Hoyer, K. and Hablesreiter, R. and Inoue, Y. and Yoshida, K. and Briest, F. and Christen, F. and Kakiuchi, N. and Yoshizato, T. and Shiozawa, Y. and Shiraishi, Y. and Striefler, J.K. and Bischoff, S. and Lohneis, P. and Putter, H. and Blau, O. and Keilholz, U. and Bullinger, L. and Pelzer, U. and Hummel, M. and Riess, H. and Ogawa, S. and Sinn, M. and Damm, F.
EBioMedicine 66 : 103327. April 2021

CTCF mediates dosage- and sequence-context-dependent transcriptional insulation by forming local chromatin domains.
Huang, H. and Zhu, Q. and Jussila, A. and Han, Y. and Bintu, B. and Kern, C. and Conte, M. and Zhang, Y. and Bianco, S. and Chiariello, A.M. and Yu, M. and Hu, R. and Tastemel, M. and Juric, I. and Hu, M. and Nicodemi, M. and Zhuang, X. and Ren, B.
Nature Genetics 53 (7): 1064-1074. July 2021

Glial cell line‐derived neurotrophic factor increases matrix metallopeptidase 9 and 14 expression in microglia and promotes microglia‐mediated glioma progression.
Huang, Y. and Zhang, B. and Haneke, H. and Haage, V. and Lubas, M. and Yuan, Y. and Xia, P. and Motta, E. and Nanvuma, C. and Dzaye, O. and Hu, F. and Kettenmann, H.
Journal of Neuroscience Research 99 (4): 1048-1063. April 2021

Skin sodium is increased in male patients with multiple sclerosis and related animal models.
Huhn, K. and Linz, P. and Pemsel, F. and Michalke, B. and Seyferth, S. and Kopp, C. and Chaudri, M.A. and Rothhammer, V. and Dörfler, A. and Uder, M. and Nagel, A.M. and Müller, D.N. and Waschbisch, A. and Lee, D.H. and Bäuerle, T. and Linker, R.A. and Haase, S.
Proceedings of the National Academy of Sciences of the United States of America 118 (28): e2102549118. 13 July 2021

ecDNA hubs drive cooperative intermolecular oncogene expression.
Hung, K.L. and Yost, K.E. and Xie, L. and Shi, Q. and Helmsauer, K. and Luebeck, J. and Schöpflin, R. and Lange, J.T. and Chamorro González, R. and Weiser, N.E. and Chen, C. and Valieva, M.E. and Wong, I.T.L. and Wu, S. and Dehkordi, S.R. and Duffy, C.V. and Kraft, K. and Tang, J. and Belk, J.A. and Rose, J.C. and Corces, M.R. and Granja, J.M. and Li, R. and Rajkumar, U. and Friedlein, J. and Bagchi, A. and Satpathy, A.T. and Tjian, R. and Mundlos, S. and Bafna, V. and Henssen, A.G. and Mischel, P.S. and Liu, Z. and Chang, H.Y.
Nature 600 (7890): 731-736. 23 December 2021

Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women.
Hur, J. and Otegbeye, E. and Joh, H.K. and Nimptsch, K. and Ng, K. and Ogino, S. and Meyerhardt, J.A. and Chan, A.T. and Willett, W.C. and Wu, K. and Giovannucci, E. and Cao, Y.
Gut 70 (12): 2330-2336. December 2021

Cortisol dose-dependently impairs migration and tube-like formation in a trophoblast cell line and modulates inflammatory and angiogenic genes.
Húngaro, T.G.R and Gregnani, M.F. and Alves-Silva, T. and Herse, F. and Alenina, N. and Bader, M. and Araújo, R.C.
Biomedicines 9 (8): 980. August 2021

A prospective of multiple biopharmaceutical activities of procyanidins‐rich Uapaca togoensis pax extracts: HPLC‐ESI‐TOF‐MS coupled with bioinformatics analysis.
Ibrahime Sinan, K. and Aktumsek, A. and de la Luz Cádiz‐Gurrea, M. and Leyva‐Jiménez, F.J. and Fernández-Ochoa, Á. and Segura‐Carretero, A. and Glamocilja, J. and Sokovic, M. and Nenadić, M. and Zengin, G.
Chemistry & Biodiversity 18 (8): e2100299. 18 August 2021

Apple peel and flesh contain pro-neurogenic compounds.
Ichwan, M. and Walker, T.L. and Nicola, Z. and Ludwig-Müller, J. and Böttcher, C. and Overall, R.W. and Adusumilli, V.S. and Bulut, M. and Sykes, A.M. and Hübner, N. and Ramirez-Rodriguez, G. and Ortiz-López, L. and Lugo-Hernández, E.A. and Kempermann, G.
Stem Cell Reports 16 (3): 548-565. 9 March 2021

Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.
Iftekhar, A. and Berger, H. and Bouznad, N. and Heuberger, J. and Boccellato, F. and Dobrindt, U. and Hermeking, H. and Sigal, M. and Meyer, T.F.
Nature Communications 12 (1): 1003. 12 February 2021

Defence and adaptation mechanisms of the intestinal epithelium upon infection.
Iftekhar, A. and Sigal, M.
International Journal of Medical Microbiology 311 (3): 151486. April 2021

Clinical outcome of older adults with acute myeloid leukemia: an analysis of a large tertiary referral center over two decades.
Ihlow, J. and Gross, S. and Neuendorff, N.R. and Busack, L. and Herneth, A. and Singh, A. and Schwarz, M. and Flörcken, A. and Anagnostopoulos, I. and Türkmen, S. and Burmeister, T. and Blau, I.W. and Bullinger, L. and Westermann, J.
Journal of Geriatric Oncology 12 (4): 540-549. May 2021

B cell depletion and signs of sepsis-acquired immunodeficiency in bone marrow and spleen of COVID-19 deceased.
Ihlow, J. and Michaelis, E. and Greuel, S. and Heynol, V. and Lehmann, A. and Radbruch, H. and Meinhardt, J. and Miller, F. and Herbst, H. and Corman, V.M. and Westermann, J. and Bullinger, L. and Horst, D. and von Brünneck, A.C. and Elezkurtaj, S.
International Journal of Infectious Diseases 103 : 628-635. February 2021

MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.
Imbastari, F. and Dahlmann, M. and Sporbert, A. and Ciolli Mattioli, C. and Mari, T. and Scholz, F. and Timm, L. and Twamley, S. and Migotti, R. and Walther, W. and Dittmar, G. and Rehm, A. and Stein, U.
Cellular and Molecular Life Sciences 78 (7): 3525-3542. April 2021

Subiculum as a generator of sharp wave-ripples in the rodent hippocampus.
Imbrosci, B. and Nitzan, N. and McKenzie, S. and Donoso, J.R. and Swaminathan, A. and Böhm, C. and Maier, N and Schmitz, D.
Cell Reports 35 (3): 109021. 20 April 2021

Bioenergetic profiling of human pluripotent stem cells.
Inak, G. and Henke, M.T. and Prigione, A.
Methods in Molecular Biology 2277 : 391-403. 2021

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak, G. and Rybak-Wolf, A. and Lisowski, P. and Pentimalli, T.M. and Jüttner, R. and Glažar, P. and Uppal, K. and Bottani, E. and Brunetti, D. and Secker, C. and Zink, A. and Meierhofer, D. and Henke, M.T. and Dey, M. and Ciptasari, U. and Mlody, B. and Hahn, T. and Berruezo-Llacuna, M. and Karaiskos, N. and Di Virgilio, M. and Mayr, J.A. and Wortmann, S.B. and Priller, J. and Gotthardt, M. and Jones, D.P. and Mayatepek, E. and Stenzel, W. and Diecke, S. and Kühn, R. and Wanker, E.E. and Rajewsky, N. and Schuelke, M. and Prigione, A.
Nature Communications 12 (1): 1929. 26 March 2021

Biallelic variants in PCDHGC4 cause a novel neurodevelopmental syndrome with progressive microcephaly, seizures, and joint anomalies.
Iqbal, M. and Maroofian, R. and Çavdarlı, B. and Riccardi, F. and Field, M. and Banka, S. and Bubshait, D.K. and Li, Y. and Hertecant, J. and Baig, S.M. and Dyment, D. and Efthymiou, S. and Abdullah, U. and Makhdoom, E.U.H. and Ali, Z. and Scherf de Almeida, T and Molinari, F. and Mignon-Ravix, C. and Chabrol, B. and Antony, J. and Ades, L. and Pagnamenta, A.T. and Jackson, A. and Douzgou, S. and Beetz, C. and Karageorgou, V. and Vona, B. and Rad, A. and Baig, J.M. and Sultan, T. and Alvi, J.R. and Maqbool, S. and Rahman, F. and Toosi, M.B. and Ashrafzadeh, F. and Imannezhad, S. and Karimiani, E.G. and Sarwar, Y. and Khan, S. and Jameel, M. and Noegel, A.A. and Budde, B. and Altmüller, J. and Motameny, S. and Höhne, W. and Houlden, H. and Nürnberg, P. and Wollnik, B. and Villard, L. and Alkuraya, F.S. and Osmond, M. and Hussain, M.S. and Yigit, G.
Genetics in Medicine 23 (11): 2138-2149. November 2021

Pantoea stewartii WceF is a glycan biofilm modifying enzyme with a bacteriophage tailspike-like fold.
Irmscher, T. and Roske, Y. and Gayk, I. and Dunsing, V. and Chiantia, S. and Heinemann, U. and Barbirz, S.
Journal of Biological Chemistry 296 : 100286. 2021

Dolosigranulum pigrum modulates immunity against SARS-CoV-2 in respiratory epithelial cells.
Islam, M.A. and Albarracin, L. and Melnikov, V. and Andrade, B.G.N. and Cuadrat, R.R.C. and Kitazawa, H. and Villena, J.
Pathogens 10 (6): 634. 21 May 2021

Immunobiotic Lactobacilli improve resistance of respiratory epithelial cells to SARS-CoV-2 infection.
Islam, M.A. and Albarracin, L. and Tomokiyo, M. and Valdez, J.C. and Sacur, J. and Vizoso-Pinto, M.G. and Andrade, B.G.N. and Cuadrat, R.C. and Kitazawa, H. and Villena, J.
Pathogens 10 (9): 1197. September 2021

Determination of G-protein-coupled receptor oligomerization by molecular brightness analyses in single cells.
Işbilir, A. and Serfling, R. and Möller, J. and Thomas, R. and De Faveri, C. and Zabel, U. and Scarselli, M. and Beck-Sickinger, A.G. and Bock, A. and Coin, I. and Lohse, M.J. and Annibale, P.
Nature Protocols 16 (3): 1419-1451. March 2021

Sulfoxide-functionalized nanogels inspired by the skin penetration properties of DMSO.
Işık, D. and Joshi, A.A. and Guo, X. and Rancan, F. and Klossek, A. and Vogt, A. and Rühl, E. and Hedtrich, S. and Klinger, D.
Biomaterials science 9 (3): 712-725. 7 February 2021

Assessing dysferlinopathy patients over three years with a new motor scale.
Jacobs, M. and James, M.K. and Lowes, L.P. and Alfano, L.N. and Eagle, M. and Lofra, R.M. and Moore, U. and Feng, J. and Rufibach, L.E. and Rose, K. and Duong, T. and Bello, L. and Pedrosa-Hernández, I. and Holsten, S. and Sakamoto, C. and Canal, A. and Práxedes, N.S.A. and Thiele, S. and Siener, C. and Vandevelde, B. and DeWolf, B. and Maron, E. and Guglieri, M. and Hogrel, J.Y. and Blamire, A.M. and Carlier, P.G. and Spuler, S. and Day, J.W. and Jones, K.J. and Bharucha-Goebel, D.X. and Salort-Campana, E. and Pestronk, A. and Walter, M.C. and Paradas, C. and Stojkovic, T. and Mori-Yoshimura, M. and Bravver, E. and Díaz-Manera, J. and Pegoraro, E. and Mendell, J.R. and Mayhew, A.G. and Straub, V.
Annals of Neurology 89 (5): 967-978. May 2021

Analysis of renal diffusion-weighted imaging (DWI) using apparent diffusion coefficient (ADC) and intravoxel incoherent motion (IVIM) models.
Jerome, N.P. and Periquito, J.S.
Methods in Molecular Biology 2216 : 611-635. 2021

Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant.
Jiang, H. and Hooper, C. and Kelly, M. and Steeples, V. and Simon, J.N. and Beglov, J. and Azad, A.J. and Leinhos, L. and Bennett, P. and Ehler, E. and Kalisch-Smith, J.I. and Sparrow, D.B. and Fischer, R. and Heilig, R. and Isackson, H. and Ehsan, M. and Patone, G. and Huebner, N. and Davies, B. and Watkins, H. and Gehmlich, K.
Basic Research in Cardiology 116 (1): 14. 26 February 2021

Cerebral angiogenesis ameliorates pathological disorders in Nemo-deficient mice with small-vessel disease.
Jiang, Y. and Müller, K. and Khan, M.A. and Assmann, J.C. and Lampe, J. and Kilau, K. and Richter, M. and Kleint, M. and Ridder, D.A. and Hübner, N. and Schmidt-Supprian, M. and Wenzel, J. and Schwaninger, M.
Journal of Cerebral Blood Flow and Metabolism 41 (2): 219-235. 1 February 2021

Sodium and its manifold impact on our immune system.
Jobin, K. and Müller, D.N. and Jantsch, J. and Kurts, C.
Trends in Immunology 42 (6): 469-479. June 2021

Simple sugar and sugar-sweetened beverage intake during adolescence and risk of colorectal cancer precursors: adolescent sugar intake and colorectal polyp.
Joh, H.K. and Lee, D.H. and Hur, J. and Nimptsch, K. and Chang, Y. and Joung, H. and Zhang, X. and Rezende, L.F.M. and Lee, J.E. and Ng, K. and Chen, Y. and Tabung, F.K. and Meyerhardt, J.A. and Chan, A.T. and Pischon, T. and Song, M. and Fuchs, C.S. and Willett, W.C. and Cao, Y. and Ogino, S. and Giovannucci, E. and Wu, K.
Gastroenterology 161 (1): 128-142. July 2021

Electroporation-based genetic modification of primary human pigment epithelial cells using the Sleeping Beauty transposon system.
Johnen, S. and Harmening, N. and Marie, C. and Scherman, D. and Izsvák, Z. and Ivics, Z. and Walter, P. and Thumann, G.
Journal of Visualized Experiments (168): e61987. February 2021

The gut microbiota is associated with the small intestinal paracellular permeability and the development of the immune system in healthy children during the first two years of life.
Kaczmarczyk, M. and Löber, U. and Adamek, K. and Węgrzyn, D. and Skonieczna-Żydecka, K. and Malinowski, D. and Łoniewski, I. and Markó, L. and Ulas, T. and Forslund, S.K. and Łoniewska, B.
Journal of Translational Medicine 19 (1): 177. 28 April 2021

Self-sustaining interleukin-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19.
Kaiser, R. and Leunig, A. and Pekayvaz, K. and Popp, O. and Joppich, M. and Polewka, V. and Escaig, R. and Anjum, A. and Hoffknecht, M.L. and Gold, C. and Brambs, S. and Engel, A. and Stockhausen, S. and Knottenberg, V. and Titova, A. and Haji, M. and Scherer, C. and Muenchhoff, M. and Hellmuth, J.C. and Saar, K. and Schubert, B. and Hilgendorff, A. and Schulz, C. and Kääb, S. and Zimmer, R. and Hübner, N. and Massberg, S. and Mertins, P. and Nicolai, L. and Stark, K.
JCI Insight 6 (18): e150862. 22 September 2021

Regulation of the cytochrome P450 epoxyeicosanoid pathway is associated with distinct histologic features in pediatric non-alcoholic fatty liver disease.
Kalveram, L. and Schunck, W.H. and Rothe, M. and Rudolph, B. and Loddenkemper, C. and Holzhütter, H.G. and Henning, S. and Bufler, P. and Schulz, M. and Meierhofer, D. and Zhang, I.W. and Weylandt, K.H. and Wiegand, S. and Hudert, C.A.
Prostaglandins Leukotrienes and Essential Fatty Acids 164 : 102229. January 2021

Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling.
Kamdem, N. and Roske, Y. and Kovalskyy, D. and Platonov, M.O. and Balinskyi, O. and Kreuchwig, A. and Saupe, J. and Fang, L. and Diehl, A. and Schmieder, P. and Krause, G. and Rademann, J. and Heinemann, U. and Birchmeier, W. and Oschkinat, H.
Magnetic Resonance 2 (1): 355-374. 2 June 2021

Breeding and maintenance of immunodeficient mouse lines under SPF conditions - a call for individualized severity analyses and approval procedures.
Kammertoens, T. and Jeuthe, S. and Baranzke, H. and Klippert, A. and Thöne-Reineke, C.
Animals 11 (6): 1789. June 2021

Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology.
Kargapolova, Y. and Rehimi, R. and Kayserili, H. and Brühl, J. and Sofiadis, K. and Zirkel, A. and Palikyras, S. and Mizi, A. and Li, Y. and Yigit, G. and Hoischen, A. and Frank, S. and Russ, N. and Trautwein, J. and van Bon, B. and Gilissen, C. and Laugsch, M. and Gusmao, E.G. and Josipovic, N. and Altmüller, J. and Nürnberg, P. and Längst, G. and Kaiser, F.J. and Watrin, E. and Brunner, H. and Rada-Iglesias, A. and Kurian, L. and Wollnik, B. and Bouazoune, K. and Papantonis, A.
Nature Communications 12 (1): 3014. 21 May 2021

Diagnostik und Therapie von statinassoziierten Muskelsymptomen [Diagnostics and treatment of statin-associated muscle symptoms].
Kassner, U. and Grunwald, S. and Spira, D. and Buchmann, N. and Bobbert, T. and Gazzerro, E. and Hollstein, T. and Spuler, S. and Steinhagen-Thiessen, E.
Internist 62 : 827-840. August 2021

Reconstitution of β-adrenergic regulation of Ca(V)1.2: Rad-dependent and Rad-independent protein kinase A mechanisms.
Katz, M. and Subramaniam, S. and Chomsky-Hecht, O. and Tsemakhovich, V. and Flockerzi, V. and Klussmann, E. and Hirsch, J.A. and Weiss, S. and Dascal, N.
Proceedings of the National Academy of Sciences of the United States of America 118 (21): e2100021118. 17 May 2021

Preparation and monitoring of small animals in renal MRI.
Kaucsar, T. and Hosszu, A. and Seeliger, E. and Reimann, H.M. and Fekete, A.
Methods in Molecular Biology 2216 : 45-55. 2021

Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide - an international collaborative study.
Kayser, S. and Schlenk, R.F. and Lebon, D. and Carre, M. and Götze, K.S. and Stölzel, F. and Berceanu, A. and Schäfer-Eckart, K. and Peterlin, P. and Hicheri, Y. and Rahme, R. and Raffoux, E. and Chermat, F. and Krause, S.W. and Aulitzky, W.E. and Rigaudeau, S. and Noppeney, R. and Berthon, C. and Görner, M. and Jost, E. and Carassou, P. and Keller, U. and Orvain, C. and Braun, T. and Saillard, C. and Arar, A. and Kunzmann, V. and Wemeau, M. and De Wit, M. and Niemann, D. and Bonmati, C. and Schwänen, C. and Abraham, J. and Aljijakli, A. and Haiat, S. and Krämer, A. and Reichle, A. and Gnadler, M. and Willekens, C. and Spiekermann, K. and Hiddemann, W. and Müller-Tidow, C. and Thiede, C. and Röllig, C. and Serve, H. and Bornhäuser, M. and Baldus, C.D. and Lengfelder, E. and Fenaux, P. and Platzbecker, U. and Adès, L.
Haematologica 106 (12): 3100-3106. December 2021

The CONJUDOR pipeline for multiplexed knockdown of gene pairs identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans.
Kazmierczak, M. and Farré i Díaz, C. and Ofenbauer, A. and Herzog, S. and Tursun, B.
Nucleic Acids Research 49 (4): e22. 26 February 2021

Kidney injury caused by preeclamptic pregnancy recovers postpartum in a transgenic rat model.
Kedziora, S.M. and Kräker, K. and Markó, L. and Binder, J. and Sugulle, M. and Gauster, M. and Mueller, D.N. and Dechend, R. and Haase, N. and Herse, F.
International Journal of Molecular Sciences 22 (7): 3762. 5 April 2021

Genomic variants causing mitochondrial dysfunction are common in hereditary lower motor neuron disease.
Keller, N. and Paketci, C. and Altmueller, J. and Fuhrmann, N. and Wunderlich, G. and Schrank, B. and Unver, O. and Yilmaz, S. and Boostani, R. and Karimiani, E.G. and Motameny, S. and Thiele, H. and Nürnberg, P. and Maroofian, R. and Yis, U. and Wirth, Br. and Karakaya, M.
Human Mutation 42 (4): 460-472. April 2021

Profiling of sub-lethal in vitro effects of multi-walled carbon nanotubes reveals changes in chemokines and chemokine receptors.
Keshavan, S. and Andón, F.T. and Gallud, A. and Chen, W. and Reinert, K. and Tran, L. and Fadeel, B.
Nanomaterials 11 (4): 883. 30 March 2021

Subclone eradication analysis identifies targets for enhanced cancer therapy and reveals L1 retrotransposition as a dynamic source of cancer heterogeneity.
Ketola, K. and Kaljunen, H. and Taavitsainen, S. and Kaarijärvi, R. and Järvelä, E. and Rodriguez Martin, B. and Haase, K. and Woodcock, D.J. and Tubio, J. and Wedge, D.C. and Nykter, M. and Bova, G.S.
Cancer Research 81 (19): 4901-4909. October 2021

Hyponatriämie - Ursachen, Diagnostik und Therapie [Hyponatremia - causes, diagnostic evaluation and treatment].
Kettritz, R.
Deutsche Medizinische Wochenschrift 146 (3): 176-180. February 2021

Volumenmanagement bei chronischen Nierenerkrankungen [Volume management in chronic kidney disease].
Kettritz, R. and Schirmer, S.H. and Heine, G.H.
Deutsche Medizinische Wochenschrift 146 (8): 518-524. April 2021

Recurrent early filter clotting during continuous veno-venous hemodialysis with regional citrate anticoagulation is linked to systemic thrombin generation and heparin induced thrombocytopenia type II: a retrospective analysis.
Khadzhynov, D. and Slowinski, T. and Schreiber, A. and Lieker, I. and Halleck, F. and Lehner, L.J. and Kindgen-Milles, D. and Eckardt, K.U. and Budde, K. and Staeck, O.
Austin Critical Care Case Reports 5 (3): 1032. 30 September 2021

MFSD2A-associated primary microcephaly - expanding the clinical and mutational spectrum of this ultra-rare disease.
Khuller, K. and Yigit, G. and Martínez Grijalva, C. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Elcioglu, N.H. and Yeter, B. and Hehr, U. and Stein, A. and Della Marina, A. and Köninger, A. and Depienne, C. and Kaiser, F.J. and Wollnik, B. and Kuechler, A.
European Journal of Medical Genetics 64 (10): 104310. October 2021

Characterization and modulation of anti- αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Kierkels, G.J.J. and van Diest, E. and Hernández-López, P. and Scheper, W. and de Bruin, A.C.M. and Frijlink, E. and Aarts-Riemens, T. and van Dooremalen, S.F.J. and Beringer, D.X. and Oostvogels, R. and Kramer, L. and Straetemans, T. and Uckert, W. and Sebestyén, Z. and Kuball, J.
Molecular Therapy - Methods and Clinical Development 22 (10): 388-400. 10 September 2021

Donor cell memory confers a metastable state of directly converted cells.
Kim, K.P. and Li, C. and Bunina, D. and Jeong, H.W. and Ghelman, J. and Yoon, J. and Shin, B. and Park, H. and Han, D.W. and Zaugg, J.B. and Kim, J. and Kuhlmann, T. and Adams, R.H. and Noh, K.M. and Goldman, S.A. and Schöler, H.R.
Cell Stem Cell 28 (7): 1291-1306. 1 July 2021

Design and synthesis of novel fluorescently labeled analogs of vemurafenib targeting MKK4.
Kircher, T. and Pantsar, T. and Oder, A. and von Kries, J.P. and Juchum, M. and Pfaffenrot, B. and Kloevekorn, P. and Albrecht, W. and Selig, R. and Laufer, S.
European Journal of Medicinal Chemistry 2019 : 112901. 1 January 2021

ENHANCED GRAVITROPISM 2 encodes a STERILE ALPHA MOTIF–containing protein that controls root growth angle in barley and wheat.
Kirschner, G.K. and Rosignoli, S. and Guo, L. and Vardanega, I. and Imani, J. and Altmüller, J. and Milner, S.G. and Balzano, R: and Nagel, K.A. and Pflugfelder, D. and Forestan, C. and Bovina, R. and Koller, R. and Stöcker, T.G. and Mascher, M. and Simmonds, J. and Uauy, C. and Schoof, H. and Tuberosa, R. and Salvi, S. and Hochholdinger, F.
Proceedings of the National Academy of Sciences of the United States of America 118 (35): e2101526118. 31 August 2021

UNC93B1 is widely expressed in the murine CNS and is required for neuroinflammation and neuronal injury induced by microRNA let-7b.
Klammer, M.G. and Dzaye, O. and Wallach, T. and Krüger, C. and Gaessler, D. and Buonfiglioli, A. and Derkow, K. and Kettenmann, H. and Brinkmann, M.M. and Lehnardt, S.
Frontiers in Immunology 12 : 715774. September 2021

Schizophrenia risk candidate protein ZNF804A interacts with STAT2 and influences interferon-mediated gene transcription in mammalian cells.
Klockmeier, K. and Silva Ramos, E. and Raskó, T. and Martí Pastor, A. and Wanker, E.E.
Journal of Molecular Biology 433 (19): 167184. 17 September 2021

ANK3 related neurodevelopmental disorders: expanding the spectrum of heterozygous loss-of-function variants.
Kloth, K. and Lozic, B. and Tagoe, J. and Hoffer, M.J.V. and Van der Ven, A. and Thiele, H. and Altmüller, J. and Kubisch, C. and Au, P.Y.B. and Denecke, J. and Bijlsma, E.K. and Lessel, D.
Neurogenetics 22 (4): 263-269. October 2021

Retinal thickness analysis in progressive multiple sclerosis patients treated with epigallocatechin gallate: optical coherence tomography results from the SUPREMES study.
Klumbies, K. and Rust, R. and Dörr, J. and Konietschke, F. and Paul, F. and Bellmann-Strobl, J. and Brandt, A.U. and Zimmermann, H.G.
Frontiers in Neurology 12 : 615790. 28 April 2021

Mutations in transcription factor CP2-like 1 may cause a novel syndrome with distal renal tubulopathy in humans.
Klämbt, V. and Werth, M. and Onuchic-Whitford, A.C. and Getwan, M. and Kitzler, T.M. and Buerger, F. and Mao, Y. and Deutsch, K. and Mann, N. and Majmundar, A.J. and Kaminski, M.M. and Shen, Tian and Schmidt-Ott, K.M. and Shalaby, M. and El Desoky, S. and Kari, J.A. and Shril, S. and Lienkamp, S.S. and Barasch, J. and Hildebrandt, F.
Nephrology Dialysis Transplantation 36 (2): 237-246. February 2021

Bioaccumulation of therapeutic drugs by human gut bacteria.
Klünemann, M. and Andrejev, S. and Blasche, S. and Mateus, A. and Phapale, P. and Devendran, S. and Vappiani, J. and Simon, B. and Scott, T.A. and Kafkia, E. and Konstantinidis, D. and Zirngibl, K. and Mastrorilli, E. and Banzhaf, M. and Mackmull, M.T. and Hövelmann, F. and Nesme, L. and Brochado, A.R. and Maier, L. and Bock, T. and Periwal, V. and Kumar, M. and Kim, Y. and Tramontano, M. and Schultz, C. and Beck, M. and Hennig, J. and Zimmermann, M. and Sévin, D.C. and Cabreiro, F. and Savitski, M.M. and Bork, P. and Typas, A. and Patil, K.R.
Nature 597 : 533-538. 23 September 2021

The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Kobelt, D. and Perez-Hernandez, D. and Fleuter, C. and Dahlmann, M. and Zincke, F. and Smith, J. and Migotti, R. and Popp, O. and Burock, S. and Walther, W. and Dittmar, G. and Mertins, P. and Stein, U.
Oncogene 40 (34): 5286-5301. 26 August 2021

Real-time cell migration monitoring to analyze drug synergism in the scratch assay using the IncuCyte system.
Kobelt, D. and Walther, W. and Stein, U.S.
Methods in Molecular Biology 2294 : 133-142. 2021

Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility.
Koester, J. and Miroshnikova, Y.A. and Ghatak, S. and Chacón-Martínez, C.A. and Morgner, J. and Li, X. and Atanassov, I. and Altmüller, J. and Birk, D.E. and Koch, M. and Bloch, W. and Bartusel, M. and Niessen, C.M. and Rada-Iglesias, A. and Wickström, S.A.
Nature Cell Biology 23 (7): 771-781. July 2021

An identical-by-descent novel splice-donor variant in PRUNE1 causes a neurodevelopmental syndrome with prominent dystonia in two consanguineous Sudanese families.
Koko, M. and Yahia, A. and Elsayed, L.E. and Hamed, A.A. and Mohammed, I.N. and Elseed, M.A. and Hamad, M.H.A. and Babai, A.M. and Siddig, R.A. and Abd Allah, A.S.I. and Mohamed, M. and El-Amin, M. and Esteves, T. and Altmüller, J. and Toliat, M.R. and Thiele, H. and Nürnberg, P. and Salih, M.A. and Ahmed, A.E. and Lerche, H. and Stevanin, G.
Annals of Human Genetics 85 (5): 186-195. September 2021

Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence.
Kolesnichenko, M. and Mikuda, N. and Höpken, U.E. and Kärgel, E. and Uyar, B. and Tufan, A.B. and Milanovic, M. and Sun, W. and Krahn, I. and Schleich, K. and von Hoff, L. and Hinz, M. and Willenbrock, M. and Jungmann, S. and Akalin, A. and Lee, S. and Schmidt-Ullrich, R. and Schmitt, C.A. and Scheidereit, C.
EMBO Journal 40 (6): e104296. 15 March 2021

Effects of daytime dry fasting on hydration, glucose metabolism and circadian phase: a prospective exploratory cohort study in Bahá'í volunteers.
Koppold-Liebscher, D.A. and Klatte, C. and Demmrich, S. and Schwarz, J. and Kandil, F.I. and Steckhan, N. and Ring, R. and Kessler, C.S. and Jeitler, M. and Koller, B. and Ananthasubramaniam, B. and Eisenmann, C. and Mähler, A. and Boschmann, M. and Kramer, A. and Michalsen, A.
Frontiers in Nutrition 8 : 662310. July 2021

Adaptive physiological water conservation explains hypertension and muscle catabolism in experimental chronic renal failure.
Kovarik, J. and Morisawa, N. and Wild, J. and Marton, A. and Takase-Minegishi, K. and Minegishi, S. and Daub, S. and Sands, J.M. and Klein, J.D. and Bailey, J.L. and Kovalik, J.P. and Rauh, M. and Karbach, S. and Hilgers, K.F. and Luft, F. and Nishiyama, A. and Nakano, D. and Kitada, K. and Titze, J.
Acta Physiologica 232 (1): e13629. May 2021

Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds.
Kowalczyk, I. and Lee, C. and Schuster, E. and Hoeren, J. and Trivigno, V. and Riedel, L. and Görne, J. and Wallingford, J.B. and Hammes, A. and Feistel, K.
Development 148 (2): dev195008. 26 January 2021

Predictors of major atrial fibrillation endpoints in the National Heart, Lung, and Blood Institute HCMR.
Kramer, C.M. and DiMarco, J.P. and Kolm, P. and Ho, C.Y. and Desai, M.Y. and Kwong, R.Y. and Dolman, S.F. and Geller, N. and Kim, D.Y. and Maron, M.S. and Appelbaum, E. and Jerosch-Herold, M. and Friedrich, M.G. and Schulz-Menger, J. and Piechnik, S.K. and Mahmod, M. and Jacoby, D. and White, J. and Chiribiri, A. and Helms, A. and Choudhury, L. and Michels, M. and Bradlow, W. and Salerno, M. and Dawson, D.K. and Weinsaft, J.W. and Berry, C. and Nagueh, S.F. and Buccarelli-Ducci, C. and Anjali, O. and Casadei, B. and Watkins, H. and Weintraub, W.S. and Neubauer, S.
JACC: Clinical Electrophysiology 7 (11): 1376-1386. November 2021

Protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit.
Kraushar, M.L. and Krupp, F. and Harnett, D. and Turko, P. and Ambrozkiewicz, M.C. and Sprink, T. and Imami, K. and Günnigmann, M. and Zinnall, U. and Vieira-Vieira, C.H. and Schaub, T. and Münster-Wandowski, A. and Bürger, J. and Borisova, E. and Yamamoto, H. and Rasin, M.R. and Ohler, U. and Beule, D. and Mielke, T. and Tarabykin, V. and Landthaler, M. and Kramer, G. and Vida, I. and Selbach, M. and Spahn, C.M.T.
Molecular Cell 81 (2): 304-322. 21 January 2021

PET-guided eBEACOPP treatment of advanced-stage Hodgkin lymphoma (HD18): follow-up analysis of an international, open-label, randomised, phase 3 trial.
Kreissl, S. and Goergen, H. and Buehnen, I. and Kobe, C. and Moccia, A. and Greil, R. and Eichenauer, D.A. and Zijlstra, J.M. and Markova, J. and Meissner, J. and Feuring-Buske, M. and Soekler, M. and Beck, H.J. and Willenbacher, W. and Ludwig, W.D. and Pabst, T. and Topp, M.S. and Hitz, F. and Bentz, M. and Keller, U.B. and Kühnhardt, D. and Ostermann, H. and Hertenstein, B. and Aulitzky, W. and Maschmeyer, G. and Vieler, T. and Eich, H. and Baues, C. and Stein, H. and Fuchs, M. and Diehl, V. and Dietlein, M. and Engert, A. and Borchmann, P.
Lancet Haematology 8 (6): e398-e409. June 2021

Encephalitis patient-derived monoclonal GABA(A) receptor antibodies cause epileptic seizures.
Kreye, J. and Wright, S.K. and van Casteren, A. and Stoeffler, L. and Machule, M.L. and Reincke, S.M. and Nikolaus, M. and van Hoof, S. and Sanchez-Sendin, E. and Homeyer, M.A. and Gómez, C.C. and Kornau, H.C. and Schmitz, D. and Kaindl, A.M. and Boehm-Sturm, P. and Mueller, S. and Wilson, M.A. and Upadhya, M.A. and Dhangar, D.R. and Greenhill, S. and Woodhall, G. and Turko, P. and Vida, I. and Garner, C.C. and Wickel, J. and Geis, C. and Fukata, Y. and Fukata, M. and Prüss, H.
Journal of Experimental Medicine 218 (11): e20210012. 1 November 2021

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities.
Kruse, T. and Benz, C. and Garvanska, D.H. and Lindqvist, R. and Mihalic, F. and Coscia, F. and Inturi, R. and Sayadi, A. and Simonetti, L. and Nilsson, E. and Ali, M. and Kliche, J. and Moliner Morro, A. and Mund, A. and Andersson, E. and McInerney, G. and Mann, M. and Jemth, P. and Davey, N.E. and Överby, A.K. and Nilsson, J. and Ivarsson, Y.
Nature Communications 12 (1): 6761. 19 November 2021

MEG reveals preference specific increases of sexual-image-evoked responses in paedophilic sexual offenders and healthy controls.
Krylova, M. and Ristow, I. and Marr, V. and Borchardt, V. and Li, M. and Witzel, J. and Drumkova, K. and Harris, J.A. and Zacharias, N. and Schiltz, K. and Amelung, T. and Beier, K.M. and Kruger, T.H.C. and Ponseti, J. and Schiffer, B. and Walter, H. and Kärgel, C. and Walter, M.
World Journal of Biological Psychiatry 22 (4): 257-270. April 2021

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.
Krämer, B. and Knoll, R. and Bonaguro, L. and ToVinh, M. and Raabe, J. and Astaburuaga-García, R. and Schulte-Schrepping, J. and Kaiser, K.M. and Rieke, G.J. and Bischoff, J. and Monin, M.B. and Hoffmeister, C. and Schlabe, S. and De Domenico, E. and Reusch, N. and Händler, K. and Reynolds, G. and Blüthgen, N. and Hack, G. and Finnemann, C. and Nischalke, H.D. and Strassburg, C.P. and Stephenson, E. and Su, Y. and Gardner, L. and Yuan, D. and Chen, D. and Goldman, J. and Rosenstiel, P. and Schmidt, S.V. and Latz, E. and Hrusovsky, K. and Ball, A.J. and Johnson, J.M. and Koenig, P.A. and Schmidt, F.I. and Haniffa, M. and Heath, J.R. and Kümmerer, B.M. and Keitel, V. and Jensen, B. and Stubbemann, P. and Kurth, F. and Sander, L.E. and Sawitzki, B. and Aschenbrenner, A.C. and Schultze, J.L. and Nattermann, J.
Immunity 54 (11): 2650-2669. 9 November 2021

Noninvasive renal perfusion measurement using arterial spin labeling (ASL) MRI: basic concept.
Ku, M.C. and Fernández-Seara, M.A. and Kober, F. and Niendorf, T.
Methods in Molecular Biology 2216 : 229-239. 2021

Cardiovascular magnetic resonance detects microvascular dysfunction in a mouse model of hypertrophic cardiomyopathy.
Ku, M.C. and Kober, F. and Lai, Y.C. and Pohlmann, A. and Qadri, F. and Bader, M. and Carrier, L. and Niendorf, T.
Journal of Cardiovascular Magnetic Resonance 23 (1): 63. 31 May 2021

Fluorine ((19)F) MRI for assessing inflammatory cells in the kidney: experimental protocol.
Ku, M.C. and Schreiber, A. and Delgado, P.R. and Boehm-Sturm, P. and Kettritz, R. and Niendorf, T. and Pohlmann, A. and Waiczies, S.
Methods in Molecular Biology 2216 : 495-507. 2021

Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation.
Kubo, N. and Ishii, H. and Xiong, X. and Bianco, S. and Meitinger, F. and Hu, R. and Hocker, J.D. and Conte, M. and Gorkin, D. and Yu, M. and Li, B. and Dixon, J.R. and Hu, M. and Nicodemi, M. and Zhao, H. and Ren, B.
Nature Structural & Molecular Biology 28 (2): 152-161. February 2021

Neuronal autophagy regulates presynaptic neurotransmission by controlling the axonal endoplasmic reticulum.
Kuijpers, M. and Kochlamazashvili, G. and Stumpf, A. and Puchkov, D. and Swaminathan, A. and Lucht, M.T. and Krause, E. and Maritzen, T. and Schmitz, D. and Haucke, V.
Neuron 109 (2): 299-313. 20 January 2021

Dynamic changes in microbiome composition following Mare's milk intake for prevention of collateral antibiotic effect.
Kushugulova, A. and Löber, U. and Akpanova, S. and Rysbekov, K. and Kozhakhmetov, S. and Khassenbekova, Z. and Essex, M. and Nurgozhina, A. and Nurgaziyev, M. and Babenko, D. and Markó, L. and Forslund, S.K.
Frontiers in Cellular and Infection Microbiology 11 : 622735. 21 April 2021

Markers of myocardial damage predict mortality in patients with aortic stenosis.
Kwak, S. and Everett, R.J. and Treibel, T.A. and Yang, S. and Hwang, D. and Ko, T. and Williams, M.C. and Bing, R. and Singh, T. and Joshi, S. and Lee, H. and Lee, W. and Kim, Y.J. and Chin, C.W.L. and Fukui, M. and Al Musa, T. and Rigolli, M. and Singh, A. and Tastet, L. and Dobson, L.E. and Wiesemann, S. and Ferreira, V.M. and Captur, G. and Lee, S. and Schulz-Menger, J. and Schelbert, E.B. and Clavel, M.A. and Park, S.J. and Rheude, T. and Hadamitzky, M. and Gerber, B.L. and Newby, D.E. and Myerson, S.G. and Pibarot, P. and Cavalcante, J.L. and McCann, G.P. and Greenwood, J.P. and Moon, J.C. and Dweck, M.R. and Lee, S.P.
Journal of the American College of Cardiology 78 (6): 545-558. 10 August 2021

Sekundäre Immundefekte bei hämatoonkologischen Erkrankungen.
Käbisch, E. and Na, I.K.
Tagliche Praxis 65 (1): 12-23. 2021

Sekundäre Immundefekte bei hämatoonkologischen Erkrankungen [Secondary immunodeficiency in hematological and oncological diseases].
Käbisch, E. and Na, I.K.
Internistische Praxis 63 (4): 570-581. 2021

Health workforce response to Covid-19: What pandemic preparedness planning and action at the federal and state levels in Germany? Germany's health workforce responses to Covid-19.
Köppen, J. and Hartl, K. and Maier, C.B.
International Journal of Health Planning and Management 36 (S1): 71-91. May 2021

MicroRNA-7a2 regulates prolactin in developing lactotrophs and prolactinoma cells.
LaPierre, M.P. and Godbersen, S. and Esteban, M.T. and Schad, A.N. and Treier, M. and Ghoshdastider, U. and Stoffel, M.
Endocrinology 162 (2): bqaa220. February 2021

Survey of long-term experiences of sperm cryopreservation in oncological and non-oncological patients: usage and reproductive outcomes of a large monocentric cohort.
Lackamp, N. and Wilkemeyer, I. and Jelas, I. and Keller, U. and Bullinger, L. and Stintzing, S. and le Coutre, P.
Frontiers in Oncology 11 : 772809. 5 November 2021

Met and Cxcr4 cooperate to protect skeletal muscle stem cells against inflammation-induced damage during regeneration.
Lahmann, I. and Griger, J. and Chen, J.S. and Zhang, Y. and Schülke, M. and Birchmeier-Kohler, C.
eLife 10 : e57356. 5 August 2021

Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling.
Lareau, C.A. and Ludwig, L.S. and Muus, C. and Gohil, S.H. and Zhao, T. and Chiang, Z. and Pelka, K. and Verboon, J.M. and Luo, W. and Christian, E. and Rosebrock, D. and Getz, G. and Boland, G.M. and Chen, F. and Buenrostro, J.D. and Hacohen, N. and Wu, C.J. and Aryee, M.J. and Regev, A. and Sankaran, V.G.
Nature Biotechnology 39 (4): 451-461. April 2021

Clinical presentation and management of a dinutuximab beta extravasation in a patient with neuroblastoma.
Launspach, M. and Seif, M. and Thole, TM. and Jesse, P. and Schulz, J. and Schulte, J.H. and Bischoff, S. and Eggert, A. and Deubzer, H.E.
Children 8 (2): 91. 29 January 2021

Generation of human brain organoids for mitochondrial disease modeling.
Le, S. and Petersilie, L. and Inak, G. and Menacho-Pando, C. and Kafitz, K.W. and Rybak-Wolf, A. and Rajewsky, N. and Rose, C.R. and Prigione, A.
Journal of Visualized Experiments (172): e62756. 21 June 2021

Virus-induced senescence is driver and therapeutic target in COVID-19.
Lee, S. and Yu, Y. and Trimpert, J. and Benthani, F. and Mairhofer, M. and Richter-Pechanska, P. and Wyler, E. and Belenki, D. and Kaltenbrunner, S. and Pammer, M. and Kausche, L. and Firsching, T.C. and Dietert, K. and Schotsaert, M. and Martínez-Romero, C. and Singh, G. and Kunz, S. and Niemeyer, D. and Ghanem, R. and Salzer, H.J.F. and Paar, C. and Mülleder, M. and Uccellini, M. and Michaelis, E.G. and Khan, A. and Lau, A. and Schönlein, M. and Habringer, A. and Tomasits, J. and Adler, J.M. and Kimeswenger, S. and Gruber, A.D. and Hoetzenecker, W. and Steinkellner, H. and Purfuerst, B. and Motz, R. and Di Pierro, F. and Lamprecht, B. and Osterrieder, N. and Landthaler, M. and Drosten, C. and García-Sastre, A. and Langer, R. and Ralser, M. and Eils, R. and Reimann, M. and Fan, D.N.Y. and Schmitt, C.A.
Nature 599 : 283-289. 11 November 2021

Development of a 1,2,4-triazole-based lead tankyrase inhibitor: part II.
Leenders, R.G.G. and Brinch, S.A. and Sowa, S.T. and Amundsen-Isaksen, E. and Galera-Prat, A. and Murthy, S. and Aertssen, S. and Smits, J.N. and Nieczypor, P. and Damen, E. and Wegert, A. and Nazaré, M. and Lehtiö, L. and Waaler, J. and Krauss, S.
Journal of Medicinal Chemistry 64 (24): 17936-17949. 23 December 2021

Targeted disruption of galectin 3 in mice delays the first wave of spermatogenesis and increases germ cell apoptosis.
Lei, T. and Blois, S.M. and Freitag, N. and Bergmann, M. and Bhushan, S. and Wahle, E. and Huang, A.C.C. and Chen, H.L. and Hartmann, M.F. and Wudy, S.A. and Liu, F.T. and Meinhardt, A. and Fijak, M.
Cellular and Molecular Life Sciences 78 (7): 3621-3635. April 2021

Nuclei isolation from adult mouse kidney for single-nucleus RNA-sequencing.
Leiz, J. and Hinze, C. and Boltengagen, A. and Braeuning, C. and Kocks, C. and Rajewsky, N. and Schmidt-Ott, K.M.
Journal of Visualized Experiments (175): e62901. September 2021

Technologies for profiling the impact of genomic variants on transcription factor binding.
Leiz, J. and Rutkiewicz, M. and Birchmeier, C. and Heinemann, U. and Schmidt-Ott, K.M.
Medizinische Genetik 33 (2): 147-155. 14 August 2021

Circulating HLA-G and its association with cardiovascular markers in pregnancy.
Lekva, T. and Jacobsen, D.P. and Sugulle, M. and Moe, K. and Fjeldstad, H.E.S. and Dechend, R. and Staff, A.C.
Journal of Reproductive Immunology 146 : 103331. August 2021

The Collaborative Research Center FONDA.
Leser, U. and Hilbrich, M. and Draxl, C. and Eisert, P. and Grunske, L. and Hostert, P. and Kainmüller, D. and Kao, O. and Kehr, B. and Kehrer, T. and Koch, C. and Markl, V. and Meyerhenke, H. and Rabl, T. and Reinefeld, A. and Reinert, K. and Ritter, K. and Scheuermann, B. and Schintke, F. and Schweikardt, N. and Weidlich, M.
Datenbank-Spektrum 21 : 255-260. November 2021

SMART: recent updates, new developments and status in 2020.
Letunic, I. and Khedkar, S. and Bork, P.
Nucleic Acids Research 49 (D1): D458-D460. 8 January 2021

The somatosensory world of the African naked mole-rat.
Lewin, G.R. and Smith, E.S.J. and Reznick, J. and Debus, K.Y. and Barker, A.J. and Park, T.J.
Advances in Experimental Medicine and Biology 1319 (1319): 197-220. 24 August 2021

Investigation of spleen CXCR4 expression by [(68)Ga]Pentixafor PET in a cohort of 145 solid cancer patients.
Lewis, R. and Habringer, S. and Kircher, M. and Hefter, M. and Peuker, C.A. and Werner, R. and Ademaj-Kospiri, V. and Gäble, A. and Weber, W. and Wester, H.J. and Buck, A. and Herhaus, P. and Lapa, C. and Keller, U.
EJNMMI Research 11 (1): 77. 21 August 2021

CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness.
Lewis, R. and Maurer, H.C. and Singh, N. and Gonzalez-Menendez, I. and Wirth, M. and Schick, M. and Zhang, L. and Isaakidis, K. and Scherger, A.K. and Schulze, V. and Lu, J. and Zenz, T. and Steiger, K. and Rad, R. and Quintanilla-Martinez, L. and Espeli, M. and Balabanian, K. and Keller, U. and Habringer, S.
Leukemia 35 : 2895-2905. October 2021

Single-dose MGTA-145/plerixafor leads to efficient mobilization and in vivo transduction of HSCs with thalassemia correction in mice.
Li, C. and Goncalves, K.A. and Raskó, T. and Pande, A. and Gil, S. and Liu, Z. and Izsvák, Z. and Papayannopoulou, T. and Davis, J.C. and Kiem, H.P. and Lieber, A.
Blood Advances 5 (5): 1239-1249. 9 March 2021

Coupling proteomics and metabolomics for the unsupervised identification of protein-metabolite interactions in Chaetomium thermophilum.
Li, Y. and Kuhn, M. and Zukowska-Kasprzyk, J. and Hennrich, M.L. and Kastritis, P.L. and O'Reilly, F.J. and Phapale, P. and Beck, M. and Gavin, A.C. and Bork, P.
PLoS ONE 16 (7): e0254429. 9 July 2021

Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma.
Liang, H.C. and Costanza, M. and Prutsch, N. and Zimmerman, M.W. and Gurnhofer, E. and Montes-Mojarro, I.A. and Abraham, B.J. and Prokoph, N. and Stoiber, S. and Tangermann, S. and Lobello, C. and Oppelt, J. and Anagnostopoulos, I. and Hielscher, T. and Pervez, S. and Klapper, W. and Zammarchi, F. and Silva, D.A. and Garcia, K.C. and Baker, D. and Janz, M. and Schleussner, N. and Fend, F. and Pospíšilová, Š. and Janiková, A. and Wallwitz, J. and Stoiber, D. and Simonitsch-Klupp, I. and Cerroni, L. and Pileri, S. and de Leval, L. and Sibon, D. and Fataccioli, V. and Gaulard, P. and Assaf, C. and Knörr, F. and Damm-Welk, C. and Woessmann, W. and Turner, S.D. and Look, A.T. and Mathas, S. and Kenner, L. and Merkel, O.
Nature Communications 12 (1): 5577. 22 September 2021

The SNAG domain of Insm1 regulates pancreatic endocrine cell differentiation and represses beta- to delta-cell transdifferentiation.
Liang, X. and Duan, H. and Mao, Y. and Koestner, U. and Wei, Y. and Deng, F. and Zhuang, J. and Li, H. and Wang, C. and Hernandez-Miranda, L.R. and Tao, W. and Jia, S.
Diabetes 70 (5): 1084-1097. May 2021

Predicting lethal courses in critically ill COVID-19 patients using a machine learning model trained on patients with non-COVID-19 viral pneumonia.
Lichtner, G. and Balzer, F. and Haufe, S. and Giesa, N. and Schiefenhövel, F. and Schmieding, M. and Jurth, C. and Kopp, W. and Akalin, A. and Schaller, S.J. and Weber-Carstens, S. and Spies, C. and von Dincklage, F.
Scientific Reports 11 (1): 13205. 24 June 2021

Resting state brain network functional connectivity is not associated with inflammatory markers and blood cell counts in older adults.
Lichtner, G. and Zacharias, N. and Spies, C.D. and Feinkohl, I. and Winterer, G. and Pischon, T. and von Dincklage, F.
Clinical Neurophysiology 132 (7): 1677-1686. July 2021

Beyond Ca(2+) signalling: the role of TRPV3 in the transport of NH(4).
Liebe, H. and Liebe, F. and Sponder, G. and Hedtrich, S. and Stumpff, F.
Pflugers Archiv 473 (12): 1859-1884. December 2021

Polatuzumab vedotin as a salvage and bridging treatment in relapsed or refractory large B-cell lymphomas.
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Blood Advances 5 (13): 2707-2716. 13 July 2021

Quantification of myocardial strain assessed by cardiovascular magnetic resonance feature tracking in healthy subjects - influence of segmentation and analysis software.
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European Radiology 31 (6): 3962-3972. 4 June 2021

The receptor AT1 appears to be important for the maintenance of bone mass and AT2 receptor function in periodontal bone loss appears to be regulated by AT1 receptor.
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International Journal of Molecular Sciences 22 (23): 12849. 27 November 2021

AT1 and AT2 receptor knockout changed osteonectin and bone density in mice in periodontal inflammation experimental model.
Lima, M.L.S. and Medeiros, C.A.C.X. and Guerra, G.C.B. and Santos, R. and Bader, M. and Pirih, F.Q. and Araújo Júnior, R.F. and Chan, A.B. and Cruz, L.J. and Brito, G.A.C. and Leitão, R.F.C. and Silveira, EJ.D. and Garcia, V.B. and Martins, A.A. and Araújo, A.A.
International Journal of Molecular Sciences 22 (10): 5217. 14 May 2021

hiPSC-derived epidermal keratinocytes from ichthyosis patients show altered expression of cornification markers.
Lima Cunha, D. and Oram, A. and Gruber, R. and Plank, R. and Lingenhel, A. and Gupta, M.K. and Altmüller, J. and Nürnberg, P. and Schmuth, M. and Zschocke, J. and Šarić, T. and Eckl, K.M. and Hennies, H.C.
International Journal of Molecular Sciences 22 (4): 1785. 2 February 2021

Increased serum neurofilament light and thin ganglion cell-inner plexiform layer are additive risk factors for disease activity in early multiple sclerosis.
Lin, T.Y. and Vitkova, V. and Asseyer, S. and Martorell Serra, I. and Motamedi, S. and Chien, C. and Ditzhaus, M. and Papadopoulou, A. and Benkert, P. and Kuhle, J. and Bellmann-Strobl, J. and Ruprecht, K. and Paul, F. and Brandt, A.U. and Zimmermann, H.G.
Neurology Neuroimmunology & Neuroinflammation 8 (5): e1051. September 2021

Systematic identification of MACC1-driven metabolic networks in colorectal cancer.
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Cancers 13 (5): 978. 26 February 2021

Anti-MOG antibody-associated disorders: differences in clinical profiles and prognosis in Japan and Germany.
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Journal of Neurology Neurosurgery and Psychiatry 92 (4): 377-383. April 2021

Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily.
Liu, J. and Tassinari, M. and Souza, D.P. and Naskar, S. and Noel, J.K. and Bohuszewicz, O. and Buck, M. and Williams, T.A. and Baum, B. and Low, H.H.
Cell 184 (14): 3660-3673. 8 July 2021

Kpna6 deficiency causes infertility in male mice by disrupting spermatogenesis.
Liu, N. and Qadri, F. and Busch, H. and Huegel, S. and Sihn, G. and Chuykin, I. and Hartmann, E. and Bader, M. and Rother, F.
Development 148 (19): dev.198374. 1 October 2021

The role of adiponectin and its receptor in patients with idiopathic membranous nephropathy complicated with hyperuricemia.
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Srpski Arhiv za Celokupno Lekarstvo 149 (5-6): 288-294. May 2021

Multiomic characterization of oncogenic signaling mediated by wild-type and mutant RIT1.
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Science Signaling 14 (711): eabc4520. 30 November 2021

Microglia sense neuronal activity via GABA in the early postnatal hippocampus.
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Cell Reports 37 (13): 110128. 28 December 2021

Olig3 regulates early cerebellar development.
Lowenstein, E.D. and Rusanova, A. and Stelzer, J. and Hernaiz-Llorens, M. and Schroer, A.E. and Epifanova, E. and Bladt, F. and Isik, E.G. and Buchert, S. and Jia, S. and Tarabykin, V. and Hernandez-Miranda, L.R.
eLife 10 : e64684. 16 February 2021

Cross-reactive CD4(+) T cells enhance SARS-CoV-2 immune responses upon infection and vaccination.
Loyal, L. and Braun, J. and Henze, L. and Kruse, B. and Dingeldey, M. and Reimer, U. and Kern, F. and Schwarz, T. and Mangold, M. and Unger, C. and Dörfler, F. and Kadler, S. and Rosowski, J. and Gürcan, K. and Uyar-Aydin, Z. and Frentsch, M. and Kurth, F. and Schnatbaum, K. and Eckey, M. and Hippenstiel, S. and Hocke, A. and Müller, M.A. and Sawitzki, B. and Miltenyi, S. and Paul, F. and Mall, M.A. and Wenschuh, H. and Voigt, S. and Drosten, C. and Lauster, R. and Lachman, N. and Sander, L.E. and Corman, V.M. and Röhmel, J. and Meyer-Arndt, L. and Thiel, A. and Giesecke-Thiel, C.
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Molekulargenetik der humanen Hypertonie [Molecular genetics of human hypertension].
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Arterialization requires the timely suppression of cell growth.
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Nature 589 (7842): 437-441. 21 January 2021

Cooperative binding of ETS2 and NFAT link Erk1/2 and calcineurin signaling in the pathogenesis of cardiac hypertrophy.
Luo, Y. and Jiang, N. and May, H.I. and Luo, X. and Ferdous, A. and Schiattarella, G.G. and Chen, G. and Li, Q. and Li, C. and Rothermel, B.A. and Jiang, D. and Lavandero, S. and Gillette, T.G. and Hill, J.A.
Circulation 144 (1): 34-51. 6 July 2021

Deregulated expression of circular RNAs in acute myeloid leukemia.
Lux, S. and Blätte, T.J. and Gillissen, B. and Richter, A. and Cocciardi, S. and Skambraks, S. and Schwarz, K. and Schrezenmeier, H. and Döhner, H. and Döhner, K. and Dolnik, A. and Bullinger, L.
Blood Advances 5 (5): 1490-1503. 9 March 2021

Photocaged Hoechst enables subnuclear visualization and cell selective staining of DNA in vivo.
Lämmle, C.A. and Varady, A. and Müller, T.G. and Sturtzel, C. and Riepl, M. and Mathes, B. and Eichhorst, J. and Sporbert, A. and Lehmann, M. and Kräusslich, H.G. and Distel, M. and Broichhagen, J.
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Analysis of correlation and ionization from pair distributions in many-electron systems.
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European Physical Journal Plus 136 (7): 763. 22 July 2021

Genetic background but not intestinal microbiota after co-housing determines hyperoxaluria-related nephrocalcinosis in common inbred mouse strains.
Ma, Q. and Grigorescu, M. and Schreiber, A. and Kettritz, R. and Lindenmeyer, M. and Anders, H.J. and Steiger, S.
Frontiers in Immunology 12 : 673423. 21 April 2021

A simple spatial-independent associative and reversal learning task in mice.
Magara, F. and Boury-Jamot, B. and Hörnberg, H.
Bio-protocol 11 (15): e4108. 5 August 2021

3D MRI of explanted sheep hearts with submillimeter isotropic spatial resolution: comparison between diffusion tensor and structure tensor imaging.
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Magnetic Resonance Materials in Physics Biology and Medicine 34 (5): 741-755. October 2021

Age-related decline in murine heart and skeletal muscle performance is attenuated by reduced Ahnak1 expression.
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Journal of Cachexia Sarcopenia and Muscle 12 : 1249-1265. 14 October 2021

Efficient optogenetic silencing of neurotransmitter release with a mosquito rhodopsin.
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Neuron 109 (10): 1621-1635. 19 May 2021

Unravelling the collateral damage of antibiotics on gut bacteria.
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Nature 599 : 120-124. 4 November 2021

Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients.
Maifeld, A. and Bartolomaeus, H. and Löber, U. and Avery, E.G. and Steckhan, N. and Markó, L. and Wilck, N. and Hamad, I. and Šušnjar, U. and Mähler, A. and Hohmann, C. and Chen, C.Y. and Cramer, H. and Dobos, G. and Lesker, T.R. and Strowig, T. and Dechend, R. and Bzdok, D. and Kleinewietfeld, M. and Michalsen, A. and Müller, D.N. and Forslund, S.K.
Nature Communications 12 (1): 1970. 30 March 2021

Modifier genes in microcephaly: a report on WDR62, CEP63, RAD50 and PCNT variants exacerbating disease caused by biallelic mutations of ASPM and CENPJ.
Makhdoom, E.U.H. and Waseem, S.S. and Iqbal, M. and Abdullah, U. and Hussain, G. and Asif, M. and Budde, B. and Höhne, W. and Tinschert, S. and Saadi, S.M. and Yousaf, H. and Ali, Z. and Fatima, A. and Kaygusuz, E. and Khan, A. and Jameel, M. and Khan, S. and Tariq, M. and Anjum, I. and Altmüller, J. and Thiele, H. and Höning, S. and Baig, S.M. and Nürnberg, P. and Hussain, M.S.
Genes 12 (5): 731. May 2021

Knockout of aminopeptidase A in mice causes functional alterations and morphological glomerular basement membrane changes in the kidneys.
Marahrens, B. and Schulze, A. and Wysocki, J. and Lin, M.H. and Ye, M. and Kanwar, Y.S. and Bader, M. and Velez, J.C.Q. and Miner, J.H. and Batlle, D.
Kidney International 99 (4): 900-913. April 2021

Knock-in mice expressing a 15-lipoxygenating Alox5 mutant respond differently to experimental inflammation than reported mice.
Marbach-Breitrück, E. and Rohwer, N. and Infante-Duarte, C. and Romero-Suarez, S. and Labuz, D. and Machelska, H. and Kutzner, L. and Schebb, N.H. and Rothe, M. and Reddanna, P. and Weylandt, K.H. and Wieler, L.H and Heydeck, D. and Kuhn, H.
Metabolites 11 (10): 698. 12 October 2021

GAS1 is required for Notch-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.
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Development 148 (21): dev200080. 11 November 2021

Disability outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder.
Marignier, R. and Bennett, J.L. and Kim, H.J. and Weinshenker, B.G. and Pittock, S.J. and Wingerchuk, D. and Fujihara, K. and Paul, F. and Cutter, G.R. and Green, A.J. and Aktas, O. and Hartung, H.P. and Lublin, F.D. and Williams, I.M. and Drappa, J. and She, D. and Cimbora, D. and Rees, W. and Smith, M. and Ratchford, J.N. and Katz, E. and Cree, B.A.C.
Neurology Neuroimmunology & Neuroinflammation 8 (3): e978. May 2021

Myelin-oligodendrocyte glycoprotein antibody-associated disease.
Marignier, R. and Hacohen, Y. and Cobo-Calvo, A. and Pröbstel, A.K. and Aktas, O. and Alexopoulos, H. and Amato, M.P. and Asgari, N. and Banwell, B. and Bennett, J. and Brilot, F. and Capobianco, M. and Chitnis, T. and Ciccarelli, O. and Deiva, K. and De Sèze, J. and Fujihara, K. and Jacob, A. and Kim, H.J. and Kleiter, I. and Lassmann, H. and Leite, M.I. and Linington, C. and Meinl, E. and Palace, J. and Paul, F. and Petzold, A. and Pittock, S. and Reindl, M. and Sato, D.K. and Selmaj, K. and Siva, A. and Stankoff, B. and Tintore, M. and Traboulsee, A. and Waters, P. and Waubant, E. and Weinshenker, B. and Derfuss, T. and Vukusic, S. and Hemmer, B.
Lancet Neurology 20 (9): 762-772. September 2021

Alamandine but not angiotensin-(1-7) produces cardiovascular effects at the rostral insular cortex.
Marins, F.R. and Oliveira, A.C. and Qadri, F. and Motta-Santos, D. and Alenina, N. and Bader, M. and Fontes, M.A.P. and Souza Santos, R.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 321 (3): R513-R521. 10 September 2021

Locus specific epigenetic modalities of random allelic expression imbalance.
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Nature Communications 12 (1): 5330. 9 September 2021

GAMIBHEAR: whole-genome haplotype reconstruction from Genome Architecture Mapping data.
Markowski, J. and Kempfer, R. and Kukalev, A. and Irastorza-Azcarate, I. and Loof, G. and Kehr, B. and Pombo, A. and Rahmann, S. and Schwarz, R.F.
Bioinformatics 37 (19): 3128–3135. 1 October 2021

NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1.
Marques, C. and Unterkircher, T. and Kroon, P. and Oldrini, B. and Izzo, A. and Dramaretska, Y. and Ferrarese, R. and Kling, E. and Schnell, O. and Nelander, S. and Wagner, E.F. and Bakiri, L. and Gargiulo, G. and Carro, M.S. and Squatrito, M.
eLife 10 : e64846. 17 August 2021

CoBold: a method for identifying different functional classes of transient RNA structure features that can impact RNA structure formation in vivo.
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Nucleic Acids Research 49 (4): e19. 26 February 2021

Preexisting hypertension and pregnancy-induced hypertension reveal molecular differences in placental proteome in rodents.
Mary, S. and Small, H. and Herse, F. and Carrick, E. and Flynn, A. and Mullen, W. and Dechend, R. and Delles, C.
Physiological Genomics 53 (6): 259-268. June 2021

The relevance of the SH2 domain for c-Src functionality in triple-negative breast cancer cells.
Mayoral-Varo, V. and Sánchez-Bailón, M.P. and Calcabrini, A. and García-Hernández, M. and Frezza, V. and Martín, M.E. and González, V.M. and Martín-Pérez, J.
Cancers 13 (3): 462. 26 January 2021

Identification of disease-relevant modulators of the SHH pathway in the developing brain.
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Development 148 (17): dev199307. September 2021

Relevance of Angiotensin-(1-7) and its receptor Mas in pneumonia caused by Influenza virus and post-influenza pneumococcal infection.
Melo, E.M. and Del Sarto, J. and Vago, J.P. and Tavares, L.P. and Rago, F. and Gonçalves, A.P.F. and Machado, M.G. and Aranda-Pardos, I. and Valiate, B.V.S. and Cassali, G.D. and Pinho, V. and Sousa, L.P. and A-Gonzalez, N. and Campagnole-Santos, M.J. and Bader, M. and Santos, R.A.S. and Machado, A.V. and Ludwig, S. and Teixeira, M.M.
Pharmacological Research 163 : 105292. January 2021

Charcot-Marie-Tooth mutation in glycyl-tRNA synthetase stalls ribosomes in a pre-accommodation state and activates integrated stress response.
Mendonsa, S. and von Kuegelgen, N. and Bujanic, L. and Chekulaeva, M.
Nucleic Acids Research 49 (17): 10007-10017. 27 September 2021

Lymphocyte access to lymphoma is impaired by high endothelial venule regression.
Menzel, L. and Zschummel, M. and Crowley, T. and Franke, V. and Grau, M. and Ulbricht, C. and Hauser, A. and Siffrin, V. and Bajénoff, M. and Acton, S.E. and Akalin, A. and Lenz, G. and Willimsky, G. and Höpken, U.E. and Rehm, A.
Cell Reports 37 (4): 109878. 26 October 2021

PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice.
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Scientific Reports 11 (1): 6072. 16 March 2021

Neural processes of psychological stress and relaxation predict the future evolution of quality of life in multiple sclerosis.
Meyer-Arndt, L. and Schmitz-Hübsch, T. and Bellmann-Strobl, J. and Brandt, A.U. and Haynes, J.D. and Gold, S.M. and Paul, F. and Weygandt, M.
Frontiers in Neurology 12 : 753107. 23 November 2021

Inferring time series chromatin states for promoter-enhancer pairs based on Hi-C data.
Miko, H. and Qiu, Y. and Gaertner, B. and Sander, M. and Ohler, U.
BMC Genomics 22 (1): 84. 28 January 2021

Preparation of ex vivo rodent phantoms for developing, testing, and training MR imaging of the kidney and other organs.
Millward, J.M. and Periquito, J.S. and Delgado, P.R. and Prinz, C. and Niendorf, T. and Waiczies, S.
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Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells.
Mimitou, E.P. and Lareau, C.A. and Chen, K.Y. and Zorzetto-Fernandes, A.L. and Hao, Y. and Takeshima, Y. and Luo, W. and Huang, T.S. and Yeung, B.Z. and Papalexi, E. and Thakore, P.I. and Kibayashi, T. and Wing, J.B. and Hata, M. and Satija, R. and Nazor, K.L. and Sakaguchi, S. and Ludwig, L.S. and Sankaran, V.G. and Regev, A. and Smibert, P.
Nature Biotechnology 39 (10): 1246-1258. October 2021

Reporting guidelines for human microbiome research: the STORMS checklist.
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Nature Medicine 27 (11): 1885-1892. November 2021

Abrogating GPT2 in triple negative breast cancer inhibits tumor growth and promotes autophagy.
Mitra, D. and Vega-Rubin-de-Celis, S. and Royla, N. and Bernhardt, S. and Wilhelm, H. and Tarade, N. and Poschet, G. and Buettner, M. and Binenbaum, I. and Borgoni, S. and Vetter, M. and Kantelhardt, E.J. and Thomssen, C. and Chatziioannou, A. and Hell, R. and Kempa, S. and Müller-Decker, K. and Wiemann, S.
International Journal of Cancer 148 (8): 1993-2009. 15 April 2021

A single-embryo, single-cell time-resolved model for mouse gastrulation.
Mittnenzweig, M. and Mayshar, Y. and Cheng, S. and Ben-Yair, R. and Hadas, R. and Rais, Y. and Chomsky, E. and Reines, N. and Uzonyi, A. and Lumerman, L. and Lifshitz, A. and Mukamel, Z. and Orenbuch, A.H. and Tanay, A. and Stelzer, Y.
Cell 184 (11): 2825-2842. 27 May 2021

Miyoshi myopathy and limb girdle muscular dystrophy R2 are the same disease.
Moore, U. and Gordish, H. and Diaz-Manera, J. and James, M.K. and Mayhew, A.G. and Guglieri, M. and Torron, R.F. and Rufibach, L.E. and Feng, J. and Blamire, A.M. and Carlier, P.G. and Spuler, S. and Day, J.W. and Jones, K.J. and Bharucha-Goebel, D.X. and Salort-Campana, E. and Pestronk, A. and Walter, M.C. and Paradas, C. and Stojkovic, T. and Mori-Yoshimura, M. and Bravver, E. and Pegoraro, E. and Lowes, L.P. and Mendell, J.R. and Bushby, K. and Straub, V.
Neuromuscular Disorders 31 (4): 265-280. April 2021

Phenylalanine-hydroxylase contributes to serotonin synthesis in mice.
Mordhorst, A. and Dhandapani, P. and Matthes, S. and Mosienko, V. and Rothe, M. and Todiras, M. and Self, J. and Schunck, W.H. and Schütz, A. and Bader, M. and Alenina, N.
FASEB Journal 35 (6): e21648. June 2021

Variability of an early developmental cell population underlies stochastic laterality defects.
Moreno-Ayala, R. and Olivares-Chauvet, P. and Schäfer, R. and Junker, J.P.
Cell Reports 34 (2): 108606. 12 January 2021

Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis.
Moreno-Layseca, P. and Jäntti, N.Z. and Godbole, R. and Sommer, C. and Jacquemet, G. and Al-Akhrass, H. and Conway, J.R.W. and Kronqvist, P. and Kallionpää, R.E. and Oliveira-Ferrer, L. and Cervero, P. and Linder, S. and Aepfelbacher, M. and Zauber, H. and Rae, J. and Parton, R.G. and Disanza, A. and Scita, G. and Mayor, S. and Selbach, M. and Veltel, S. and Ivaska, J.
Nature Cell Biology 23 (10): 1073-1084. October 2021

NovoSpaRc: flexible spatial reconstruction of single-cell gene expression with optimal transport.
Moriel, N. and Senel, E. and Friedman, N. and Rajewsky, N. and Karaiskos, N. and Nitzan, M.
Nature Protocols 16 (9): 4177-4200. September 2021

Impact of uORFs in mediating regulation of translation in stress conditions.
Moro, S.G. and Hermans, C. and Ruiz-Orera, J. and Albà, M.M.
BMC Molecular and Cell Biology 22 (1): 29. 16 May 2021

Assessment of coronary artery disease during hospitalization for cancer treatment.
Mrotzek, S.M. and Lena, A. and Hadzibegovic, S. and Ludwig, R. and Al-Rashid, F. and Mahabadi, A.A. and Mincu, R.I. and Michel, L. and Johannsen, L. and Hinrichs, L. and Schuler, M. and Keller, U. and Anker, S.D. and Landmesser, U. and Rassaf, T. and Anker, M.S. and Totzeck, M.
Clinical Research in Cardiology 110 (2): 200-210. February 2021

Abnormal neonatal sodium handling in skin precedes hypertension in the SAME rat.
Mullins, L. and Ivy, J. and Ward, M. and Tenstad, O. and Wiig, H. and Kitada, K. and Manning, J. and Rakova, N. and Muller, D. and Mullins, J.
Pflugers Archiv 473 (6): 897-910. June 2021

Genetic deletion of trace-amine associated receptor 9 (TAAR9) in rats leads to decreased blood cholesterol levels.
Murtazina, R.Z. and Zhukov, I.S. and Korenkova, O.M. and Popova, E.A. and Kuvarzin, S. R. and Efimova, E.V. and Kubarskaya, L.G. and Batotsyrenova, E.G. and Zolotoverkhaya, E.A. and Vaganova, A.N. and Apryatin, S.A. and Alenina, N.V. and Gainetdinov, R.R.
International Journal of Molecular Sciences 22 (6): 2942. 2 March 2021

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
Muus, C. and Luecken, M.D. and Eraslan, G. and Sikkema, L. and Waghray, A. and Heimberg, G. and Kobayashi, Y. and Vaishnav, E.D. and Subramanian, A. and Smillie, C. and Jagadeesh, K.A. and Duong, E.T. and Fiskin, E. and Triglia, E.T. and Ansari, M. and Cai, P. and Lin, B. and Buchanan, J. and Chen, S. and Shu, J. and Haber, A.L. and Chung, H. and Montoro, D.T. and Adams, T. and Aliee, H. and Allon, S.J. and Andrusivova, Z. and Angelidis, I. and Ashenberg, O. and Bassler, K. and Bécavin, C. and Benhar, I. and Bergenstråhle, J. and Bergenstråhle, L. and Bolt, L. and Braun, E. and Bui, L.T. and Callori, S. and Chaffin, M. and Chichelnitskiy, E. and Chiou, J. and Conlon, T.M. and Cuoco, M.S. and Cuomo, A.S.E. and Deprez, M. and Duclos, G. and Fine, D. and Fischer, D.S. and Ghazanfar, S. and Gillich, A. and Giotti, B. and Gould, J. and Guo, M. and Gutierrez, A.J. and Habermann, A.C. and Harvey, T. and He, P. and Hou, X. and Hu, L. and Hu, Y. and Jaiswal, A. and Ji, L. and Jiang, P. and Kapellos, T.S. and Kuo, C.S. and Larsson, L. and Leney-Greene, M.A. and Lim, K. and Litviňuková, M. and Ludwig, L.S. and Lukassen, S. and Luo, W. and Maatz, H. and Madissoon, E. and Mamanova, L. and Manakongtreecheep, K. and Leroy, S. and Mayr, C.H. and Mbano, I.M. and McAdams, A.M. and Nabhan, A.N. and Nyquist, S.K. and Penland, L. and Poirion, O.B. and Poli, S. and Qi, C.C. and Queen, R. and Reichart, D. and Rosas, I. and Schupp, J.C. and Shea, C.V. and Shi, X. and Sinha, R. and Sit, R.V. and Slowikowski, K. and Slyper, M. and Smith, N.P. and Sountoulidis, A. and Strunz, M. and Sullivan, T.B. and Sun, D. and Talavera-López, C. and Tan, P. and Tantivit, J. and Travaglini, K.J. and Tucker, N.R. and Vernon, K.A. and Wadsworth, M.H. and Waldman, J. and Wang, X. and Xu, K. and Yan, W. and Zhao, W. and Ziegler, C.G.K.
Nature Medicine 27 (3): 546-559. 2 March 2021

Dorsal raphe serotonin neurotransmission is required for the expression of nursing behavior and for pup survival.
Muzerelle, A. and Soiza-Reilly, M. and Hainer, C. and Ruet, P.L. and Lesch, K.P. and Bader, M. and Alenina, N. and Scotto-Lomassese, S. and Gaspar, P.
Scientific Reports 11 (1): 6004. 16 March 2021

Metabolic response to daytime dry fasting in Bahá'í volunteers -- results of a preliminary study.
Mähler, A. and Jahn, C. and Klug, L. and Klatte, C. and Michalsen, A. and Koppold-Liebscher, D. and Boschmann, M.
Nutrients 14 (1): 148. 29 December 2021

3D FIB-SEM reconstruction of microtubule-organelle interaction in whole primary mouse β cells.
Müller, A. and Schmidt, D. and Xu, C.S. and Pang, S. and D'Costa, J.V. and Kretschmar, S. and Münster, C. and Kurth, T. and Jug, F. and Weigert, M. and Hess, H.F. and Solimena, M.
Journal of Cell Biology 220 (2): e202010039. 1 February 2021

Isolation of nuclei from mammalian cells and tissues for single-nucleus molecular profiling.
Nadelmann, E.R. and Gorham, J.M. and Reichart, D. and Delaughter, D.M. and Wakimoto, H. and Lindberg, E.L. and Litviňuková, M. and Maatz, H. and Curran, J.J. and Ischiu Gutierrez, D. and Hübner, N. and Seidman, C.E. and Seidman, J G
Current Protocols 1 (5): e132. May 2021

Deep learning is widely applicable to phenotyping embryonic development and disease.
Naert, T. and Çiçek, Ö. and Ogar, P. and Bürgi, M. and Shaidani, N.I. and Kaminski, M.M. and Xu, Y. and Grand, K. and Vujanovic, M. and Prata, D. and Hildebrandt, F. and Brox, T. and Ronneberger, O. and Voigt, F.F. and Helmchen, F. and Loffing, J. and Horb, M.E. and Willsey, H.R. and Lienkamp, S.S.
Development 148 (21): dev199664. 1 November 2021

Vascular tissue specific miRNA profiles reveal novel correlations with risk factors in coronary artery disease.
Neiburga, K. and Vilne, B. and Bauer, S. and Bongiovanni, D. and Ziegler, T. and Lachmann, M. and Wengert, S. and Hawe, J. and Güldener, U. and Westerlund, A. and Li, L. and Pang, S. and Yang, C. and Saar, K. and Huebner, N. and Maegdefessel, L. and Lange, R. and Krane, M. and Schunkert, H. and von Scheidt, M.
Biomolecules 11 (11): 1683. 12 November 2021

Anti-inflammatory role of Gpnmb in adipose tissue of mice.
Nickl, B. and Qadri, F. and Bader, M.
Scientific Reports 11 (1): 19614. 4 October 2021

Ophthalmic magnetic resonance imaging: where are we (heading to)?
Niendorf, T. and Beenakker, J.W.M. and Langner, S. and Erb-Eigner, K. and Bach Cuadra, M. and Beller, E. and Millward, J.M. and Niendorf, T.M. and Stachs, O.
Current Eye Research 46 (9): 1251-1270. September 2021

Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Nikolay, R. and Hilal, T. and Schmidt, S. and Qin, B. and Schwefel, D. and Vieira-Vieira, C.H. and Mielke, T. and Bürger, J. and Loerke, J. and Amikura, K. and Flügel, T. and Ueda, T. and Selbach, M. and Deuerling, E. and Spahn, C.M.T.
Molecular Cell 81 (6): 1200-1215. 18 March 2021

Dairy intake during adolescence and risk of colorectal adenoma later in life.
Nimptsch, K. and Lee, D.H. and Zhang, X. and Song, M. and Farvid, M.S. and Rezende, L.F.M. and Cao, Y. and Chan, A.T. and Fuchs, C. and Meyerhardt, J. and Nowak, J.A. and Willett, W.C. and Ogino, S. and Giovannucci, E. and Pischon, T. and Wu, K.
British Journal of Cancer 124 (6): 1160-1168. 16 March 2021

Maternal angiotensin increases placental leptin in early gestation via an alternative renin-angiotensin system pathway: suggesting a link to preeclampsia.
Nonn, O. and Fischer, C. and Geisberger, S. and El-Heliebi, A. and Kroneis, T. and Forstner, D. and Desoye, G. and Staff, A.C. and Sugulle, M. and Dechend, R. and Pecks, U. and Kollmann, M. and Stern, C. and Cartwright, J.E. and Whitley, G.S. and Thilaganathan, B. and Wadsack, C. and Huppertz, B. and Herse, F. and Gauster, M.
Hypertension 77 (5): 1723-1736. May 2021

Endophilin A2 deficiency protects rodents from autoimmune arthritis by modulating T cell activation.
Norin, U. and Rintisch, C. and Meng, L. and Forster, F. and Ekman, D. and Tuncel, J. and Klocke, K. and Bäcklund, J. and Yang, M. and Bonner, M.Y and Lahore, G.F. and James, J. and Shchetynsky, K. and Bergquist, M. and Gjertsson, I. and Hubner, N. and Bäckdahl, L. and Holmdahl, R.
Nature Communications 12 (1): 610. 27 January 2021

Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19.
Nouailles, G. and Wyler, E. and Pennitz, P. and Postmus, D. and Vladimirova, D. and Kazmierski, J. and Pott, F. and Dietert, K. and Muelleder, M. and Farztdinov, V. and Obermayer, B. and Wienhold, S.M. and Andreotti, S. and Hoefler, T. and Sawitzki, B. and Drosten, C. and Sander, L.E. and Suttorp, N. and Ralser, M. and Beule, D. and Gruber, A.D. and Goffinet, C. and Landthaler, M. and Trimpert, J. and Witzenrath, M.
Nature Communications 12 (1): 4869. 11 August 2021

Improvement in the prediction of neonatal hypoxic-ischemic encephalopathy with the integration of umbilical cord metabolites and current clinical makers.
O'Boyle, D.S. and Dunn, W.B. and O'Neill, D. and Kirwan, J.A. and Broadhurst, D.I. and Hallberg, B. and Boylan, G.B. and Murray, D.M.
Journal of Pediatrics 229 : 175-181. February 2021

Patient-specific planning for thermal magnetic resonance of glioblastoma multiforme.
Oberacker, E. and Diesch, C. and Nadobny, J. and Kuehne, A. and Wust, P. and Ghadjar, P. and Niendorf, T.
Cancers 13 (8): 1867. 2 April 2021

Differenzialdiagnostik autoimmun-entzündlicher Rückenmarkserkrankungen [Differential diagnostics of autoimmune inflammatory spinal cord diseases].
Oertel, F.C. and Scheel, M. and Chien, C. and Bischof, A. and Finke, C. and Paul, F.
Nervenarzt 92 (4): 293-306. April 2021

Retinal optical coherence tomography in neuromyelitis optica.
Oertel, F.C. and Specovius, S. and Zimmermann, H.G. and Chien, C. and Motamedi, S. and Bereuter, C. and Cook, L. and Lana Peixoto, M.A. and Fontanelle, M.A. and Kim, H.J. and Hyun, J.W. and Palace, J. and Roca-Fernandez, A. and Leite, M.I. and Sharma, S. and Ashtari, F. and Kafieh, R. and Dehghani, A. and Pourazizi, M. and Pandit, L. and D'Cunha, A. and Aktas, O. and Ringelstein, M. and Albrecht, P. and May, E. and Tongco, C. and Leocani, L. and Pisa, M. and Radaelli, M. and Martinez-Lapiscina, E.H. and Stiebel-Kalish, H. and Siritho, S. and de Seze, J. and Senger, T. and Havla, J. and Marignier, R. and Cobo-Calvo, A. and Bichuetti, D. and Tavares, I.M. and Asgari, N. and Soelberg, K. and Altintas, A. and Yildirim, R. and Tanriverdi, U. and Jacob, A. and Huda, S. and Rimler, Z. and Reid, A. and Mao-Draayer, Y. and Soto de Castillo, I. and Petzold, A. and Green, A.J. and Yeaman, M.R. and Smith, T. and Brandt, A.U. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 8 (6): e1068. November 2021

The C. elegans pseudogene sspt-16 (F55A3.7) is required to safeguard germ cells against reprogramming.
Ofenbauer, A. and Kraus, C.M. and Tursun, B.
microPublication Biology 2021 18 May 2021

Chances and challenges of a long-term data repository in multiple sclerosis: 20th birthday of the German MS registry.
Ohle, L.M. and Ellenberger, D. and Flachenecker, P. and Friede, T. and Haas, J. and Hellwig, K. and Parciak, T. and Warnke, C. and Paul, F. and Zettl, U.K. and Stahmann, A.
Scientific Reports 11 (1): 13340. 25 June 2021

Lysine acetylation regulates the interaction between proteins and membranes.
Okada, A.K. and Teranishi, K. and Ambroso, M.R. and Isas, J.M. and Vazquez-Sarandeses, E. and Lee, J.Y. and Melo, A.A. and Pandey, P. and Merken, D. and Berndt, L. and Lammers, M. and Daumke, O. and Chang, K. and Haworth, I.S. and Langen, R.
Nature Communications 12 (1): 6466. 9 November 2021

SynaptoPAC, an optogenetic tool for induction of presynaptic plasticity.
Oldani, S. and Moreno-Velasquez, L. and Faiss, L. and Stumpf, A. and Rosenmund, C. and Schmitz, D. and Rost, B.R.
Journal of Neurochemistry 156 (3): 324-336. February 2021

58/w mit zunehmender psychomotorischer Verlangsamung und Zephalgien [58/f with increasing psychomotor retardation and headache].
Onken, J.S. and Bullinger, L.
Onkologe 27 : 79-84. September 2021

GUNC: detection of chimerism and contamination in prokaryotic genomes.
Orakov, A. and Fullam, A. and Coelho, L.P. and Khedkar, S. and Szklarczyk, D. and Mende, D.R. and Schmidt, T.S.B. and Bork, P.
Genome Biology 22 (1): 178. 13 June 2021

Recruitment of release sites underlies chemical presynaptic potentiation at hippocampal mossy fiber boutons.
Orlando, M. and Dvorzhak, A. and Bruentgens, F. and Maglione, M. and Rost, B.R. and Sigrist, S.J. and Breustedt, J. and Schmitz, D.
PLoS Biology 19 (6): e3001149. 21 June 2021

First diagnosis of thrombotic thrombocytopenic purpura after SARS-CoV-2 vaccine - case report.
Osmanodja, B. and Schreiber, A. and Schrezenmeier, E. and Seelow, E.
BMC Nephrology 22 (1): 411. 11 December 2021

SIGLEC1 (CD169): a marker of active neuroinflammation in the brain but not in the blood of multiple sclerosis patients.
Ostendorf, L. and Dittert, P. and Biesen, R. and Duchow, A. and Stiglbauer, V. and Ruprecht, K. and Bellmann-Strobl, J. and Seelow, D. and Stenzel, W. and Niesner, R.A. and Hauser, A.E. and Paul, F. and Radbruch, H.
Scientific Reports 11 (1): 10299. 13 May 2021

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
Ostkamp, P. and Salmen, A. and Pignolet, B. and Görlich, D. and Andlauer, T.F.M. and Schulte-Mecklenbeck, A. and Gonzalez-Escamilla, G. and Bucciarelli, F. and Gennero, I. and Breuer, J. and Antony, G. and Schneider-Hohendorf, T. and Mykicki, N. and Bayas, A. and Then Bergh, F. and Bittner, S. and Hartung, H.P. and Friese, M.A. and Linker, R.A. and Luessi, F. and Lehmann-Horn, K. and Mühlau, M. and Paul, F. and Stangel, M. and Tackenberg, B. and Tumani, H. and Warnke, C. and Weber, F. and Wildemann, B. and Zettl, U.K. and Ziemann, U. and Müller-Myhsok, B. and Kümpfel, T. and Klotz, L. and Meuth, S.G. and Zipp, F. and Hemmer, B. and Hohlfeld, R. and Brassat, D. and Gold, R. and Gross, C.C. and Lukas, C. and Groppa, S. and Loser, K. and Wiendl, H. and Schwab, N.
Proceedings of the National Academy of Sciences of the United States of America 118 (1): e2018457118. 5 January 2021

A semi-automated organoid screening method demonstrates epigenetic control of intestinal epithelial differentiation.
Ostrop, J. and Zwiggelaar, R.T. and Terndrup Pedersen, M. and Gerbe, F. and Bösl, K. and Lindholm, H.T. and Díez-Sánchez, A. and Parmar, N. and Radetzki, S. and von Kries, J.P. and Jay, P. and Jensen, K.B. and Arrowsmith, C. and Oudhoff, M.J.
Frontiers in Cell and Developmental Biology 8 : 618552. 21 January 2021

Spontaneous degenerative aortic valve disease in New Zealand obese mice.
Ott, C. and Pappritz, K. and Hegemann, N. and John, C. and Jeuthe, S. and McAlpine, C.S. and Iwamoto, Y. and Lauryn, J.H. and Klages, J. and Klopfleisch, R. and Van Linthout, S. and Swirski, F. and Nahrendorf, M. and Kintscher, U. and Grune, T. and Kuebler, W.M. and Grune, J.
Journal of the American Heart Association 10 (23): e023131. 7 December 2021

Cultural bias in motor function patterns: potential relevance for predictive, preventive, and personalized medicine.
Otte, K. and Ellermeyer, T. and Suzuki, M. and Röhling, H.M. and Kuroiwa, R. and Cooper, G. and Mansow-Model, S. and Mori, M. and Zimmermann, H. and Brandt, A.U. and Paul, F. and Hirano, S. and Kuwabara, S. and Schmitz-Hübsch, T.
EPMA Journal 12 (1): 91-101. March 2021

Activation of tripartite motif containing 63 expression by transcription factor EB and transcription factor binding to immunoglobulin heavy chain enhancer 3 is regulated by protein kinase D and class IIa histone deacetylases.
Pablo Tortola, C. and Fielitz, B. and Li, Y. and Rüdebusch, J. and Luft, F.C. and Fielitz, J.
Frontiers in Physiology 11 : 550506. 13 January 2021

C3 and C4 complement levels in AQP4-IgG-positive NMOSD and in MOGAD.
Pache, F. and Ringelstein, M. and Aktas, O. and Kleiter, I. and Jarius, S. and Siebert, N. and Bellmann-Strobl, J. and Paul, F. and Ruprecht, K.
Journal of Neuroimmunology 360 : 577699. 15 November 2021

Altered DNA methylation profiles in SF3B1 mutated CLL patients.
Pacholewska, A. and Grimm, C. and Herling, C.D. and Lienhard, M. and Königs, A. and Timmermann, B. and Altmüller, J. and Mücke, O. and Reinhardt, H.C. and Plass, C. and Herwig, R. and Hallek, M. and Schweiger, M.R.
International Journal of Molecular Sciences 22 (17): 9337. 1 September 2021

Effective oncoleaking treatment of pancreatic cancer by claudin-targeted suicide gene therapy with Clostridium perfringens enterotoxin (CPE).
Pahle, J. and Kobelt, D. and Aumann, J. and Behrens, D. and Daberkow, O. and Mokritzkij, M. and Piontek, J. and Stein, U. and Walther, W.
Cancers 13 (17): 4393. 1 September 2021

Lateral geniculate nucleus volume changes after optic neuritis in neuromyelitis optica: a longitudinal study.
Papadopoulou, A. and Oertel, F.C. and Chien, C. and Kuchling, J. and Zimmermann, H.G. and Siebert, N. and Motamedi, S. and D'Souza, M. and Asseyer, S. and Bellmann-Strobl, J. and Ruprecht, K. and Chakravarty, M.M. and Scheel, M. and Magon, S. and Wuerfel, J. and Paul, F. and Brandt, A.U.
NeuroImage: Clinical 30 : 102608. 4 March 2021

African naked mole-rats demonstrate extreme tolerance to hypoxia and hypercapnia.
Park, T.J. and Smith, E.S.J. and Reznick, J. and Bennett, N.C. and Applegate, Daniel T and Larson, J. and Lewin, G.R.
Advances in Experimental Medicine and Biology 1319 (1319): 255-269. 24 August 2021

Optical coherence tomography in multiple sclerosis: a 3-year prospective multicenter study.
Paul, F. and Calabresi, P.A. and Barkhof, F. and Green, A.J. and Kardon, R. and Sastre-Garriga, J. and Schippling, S. and Vermersch, P. and Saidha, S. and Gerendas, B.S. and Schmidt-Erfurth, U. and Agoropoulou, C. and Zhang, Y. and Seifer, G. and Petzold, A.
Annals of Clinical and Translational Neurology 8 (12): 2235-2251. 14 December 2021

Effect of nabiximols on goal attainment scale scores in patients with treatment-resistant multiple sclerosis spasticity.
Paul, F. and Silván, C.V.
Neurodegenerative Disease Management 11 (2): 143-153. 1 March 2021

Community-wide experimental evaluation of the PROSS stability-design method.
Peleg, Y. and Vincentelli, R. and Collins, B.M. and Chen, K.E. and Livingstone, E.K. and Weeratunga, S. and Leneva, N. and Guo, Q. and Remans, K. and Perez, K. and Bjerga, G.E.K. and Larsen, Ø. and Vaněk, O. and Skořepa, O. and Jacquemin, S. and Poterszman, A. and Kjaer, S. and Christodoulou, E. and Albeck, S. and Dym, O. and Ainbinder, E. and Unger, T. and Schuetz, A. and Matthes, S. and Bader, M. and de Marco, A. and Storici, P. and Semrau, M.S. and Stolt-Bergner, P. and Aigner, C. and Suppmann, S. and Goldenzweig, A. and Fleishman, S.J.
Journal of Molecular Biology 433 (13): 166964. 25 June 2021

Longitudinal single-cell dynamics of chromatin accessibility and mitochondrial mutations in chronic lymphocytic leukemia mirror disease history.
Penter, L. and Gohil, S.H. and Lareau, C. and Ludwig, L.S. and Parry, E.M. and Huang, T. and Li, S. and Zhang, W. and Livitz, D. and Leshchiner, I. and Parida, L. and Getz, G. and Rassenti, L.Z. and Kipps, T.J. and Brown, J.R. and Davids, M.S. and Neuberg, D.S. and Livak, K.J. and Sankaran, V.G. and Wu, C.J.
Cancer Discovery 11 (12): 3048-3063. December 2021

Caveolin3 stabilizes McT1-mediated lactate/proton transport in cardiomyocytes.
Peper, J. and Kownatzki-Danger, D. and Weninger, G. and Seibertz, F. and Pronto, J.R. and Sutanto, H. and Pacheu Grau, D. and Hindmarsh, R. and Brandenburg, S. and Kohl, T. and Hasenfuβ, G. and Gotthardt, M. and Rog-Zielinska, E.A. and Wollnik, B. and Rehling, P. and Urlaub, H. and Wegener, J.W. and Heijman, J. and Voigt, N. and Cyganek, L. and Lenz, C. and Lehnart, S.E.
Circulation Research 128 (6): e102-e120. 19 March 2021

Continuous diffusion spectrum computation for diffusion-weighted magnetic resonance imaging of the kidney tubule system.
Periquito, J.S. and Gladytz, T. and Millward, J.M. and Delgado, P.R. and Cantow, K. and Grosenick, D. and Hummel, L. and Anger, A. and Zhao, K. and Seeliger, E. and Pohlmann, A. and Waiczies, S. and Niendorf, T.
Quantitative Imaging in Medicine and Surgery 11 (7): 3098-3119. July 2021

Renal MRI diffusion: experimental protocol.
Periquito, J.S. and Meier, M. and Niendorf, T. and Pohlmann, A. and Jerome, N.P.
Methods in Molecular Biology 2216 : 419-428. 2021

Analysis protocols for MRI mapping of the blood oxygenation-sensitive parameters T(2)* and T(2) in the kidney.
Periquito, J.S. and Starke, L. and Santos, C.M. and Freitas, A.C. and Loução, N. and Polo, P.G. and Nunes, R.G. and Niendorf, T. and Pohlmann, A.
Methods in Molecular Biology 2216 : 591-610. 2021

Variant profiling of colorectal adenomas from three patients of two families with MSH3-related adenomatous polyposis.
Perne, C. and Peters, S. and Cartolano, M. and Horpaopan, S. and Grimm, C. and Altmüller, J. and Sommer, A.K. and Hillmer, A.M. and Thiele, H. and Odenthal, M. and Möslein, G. and Adam, R. and Sivalingam, S. and Kirfel, J. and Schweiger, M.R. and Peifer, M. and Spier, I. and Aretz, S.
PLoS ONE 16 (11): e0259185. 29 November 2021

Augmenting the immune response against a stabilized HIV-1 Clade C envelope trimer by silica nanoparticle delivery.
Peterhoff, D. and Thalhauser, S. and Sobczak, J.M. and Mohsen, M.O. and Voigt, C. and Seifert, N. and Neckermann, P. and Hauser, A. and Ding, S. and Sattentau, Q. and Bachmann, M.F. and Breunig, M. and Wagner, R.
Vaccines 9 (6): 642. 11 June 2021

Alterations in BDNF protein concentrations in the hippocampus do not explain the pro-neurogenic effect of citalopram on adult neurogenesis.
Petermann, M. and Kronenberg, G. and Mosienko, V. and Bader, M. and Alenina, N. and Hellweg, R. and Klempin, F.
Pharmacopsychiatry 54 (3): 101-105. May 2021

Human MAIT cells respond to and suppress HIV-1.
Phetsouphanh, C. and Phalora, P. and Hackstein, C.P. and Thornhill, J. and Munier, C.M.L. and Meyerowitz, J. and Murray, L. and VanVuuren, C. and Goedhals, D. and Drexhage, L. and Moore, R. and Sattentau, Q.J. and Mak, J.Y. and Fairlie, D.P. and Fidler, S. and Kelleher, A.D. and Frater, J. and Klenerman, P.
eLife 10 : e50324. 24 December 2021

Mutations and variants of ONECUT1 in diabetes.
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Nature Medicine 27 (11): 1928-1940. November 2021

Astrocytes and oligodendrocytes in the thalamus jointly maintain synaptic activity by supplying metabolites.
Philippot, C. and Griemsmann, S. and Jabs, R. and Seifert, G. and Kettenmann, H. and Steinhäuser, C.
Cell Reports 34 (3): 108642. 19 January 2021

An expanded polyproline domain maintains mutant huntingtin soluble in vivo and during aging.
Pigazzini, M.L. and Lawrenz, M. and Margineanu, A. and Kaminski Schierle, G.S. and Kirstein, J.
Frontiers in Molecular Neuroscience 14 : 721749. 15 October 2021

Dietary macronutrient composition in relation to circulating HDL and non-HDL cholesterol: a federated individual-level analysis of cross-sectional data from adolescents and adults in 8 European studies.
Pinart, M. and Jeran, S. and Boeing, H. and Stelmach-Mardas, M. and Standl, M. and Schulz, H. and Harris, C. and von Berg, A. and Herberth, G. and Koletzko, S. and Linseisen, J. and Breuninger, T.A. and Nöthlings, U. and Barbaresko, J. and Benda, S. and Lachat, C. and Yang, C. and Gasparini, P. and Robino, A. and Rojo-Martínez, G. and Castaño, L. and Guillaume, M. and Donneau, A.F. and Hoge, A. and Gillain, N. and Avraam, D. and Burton, P.R. and Bouwman, J. and Pischon, T. and Nimptsch, K.
Journal of Nutrition 151 (8): 2317-2329. 7 August 2021

Identification and characterization of human observational studies in nutritional epidemiology on gut microbiomics for joint data analysis.
Pinart, M. and Nimptsch, K. and Forslund, S.K. and Schlicht, K. and Gueimonde, M. and Brigidi, P. and Turroni, S. and Ahrens, W. and Hebestreit, A. and Wolters, M. and Dötsch, A. and Nöthlings, U. and Oluwagbemigun, K. and Cuadrat, R.R.C. and Schulze, M.B. and Standl, M. and Schloter, M. and De Angelis, M. and Iozzo, P. and Guzzardi, M.A. and Vlaemynck, G. and Penders, J. and Jonkers, D.M.A.E. and Stemmer, M. and Chiesa, G. and Cavalieri, D. and De Filippo, C. and Ercolini, D. and De Filippis, F. and Ribet, D. and Achamrah, N. and Tavolacci, M.P. and Déchelotte, P. and Bouwman, J. and Laudes, M. and Pischon, T.
Nutrients 13 (9): 3292. September 2021

Exploration of analgesia with tramadol in the Coxsackievirus B3 myocarditis mouse model.
Pinkert, S. and Kespohl, M. and Kelm, N. and Kaya, Z. and Heuser, A. and Klingel, K. and Beling, A.
Viruses 13 (7): 1222. 24 June 2021

Induction of antigen-specific tolerance by nanobody-antigen adducts that target class-II major histocompatibility complexes.
Pishesha, N. and Harmand, T. and Smeding, L.Y. and Ma, W. and Ludwig, L.S. and Janssen, R. and Islam, A. and Xie, Y.J. and Fang, T. and McCaul, N. and Pinney, W. and Sugito, H.R. and Rossotti, M.A. and Gonzalez-Sapienza, G. and Ploegh, H.L.
Nature Biomedical Engineering 5 (11): 1389-1401. November 2021

The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains.
Pluska, L. and Jarosch, E. and Zauber, H. and Kniss, A. and Waltho, A. and Bagola, K. and von Delbrück, M. and Löhr, F. and Schulman, B.A. and Selbach, M. and Dötsch, V. and Sommer, T.
EMBO Journal 40 (6): e106094. 15 March 2021

RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation.
Poetz, F. and Corbo, J. and Levdansky, Y. and Spiegelhalter, A. and Lindner, D. and Magg, V. and Lebedeva, S. and Schweiggert, J. and Schott, J. and Valkov, E. and Stoecklin, G.
Nature Communications 12 (1): 7175. 9 December 2021

ECG scoring for the evaluation of therapy-naïve cancer patients to predict cardiotoxicity.
Pohl, J. and Mincu, R.I. and Mrotzek, S.M. and Wakili, R. and Mahabadi, A.A. and Potthoff, S.K. and Siveke, J.T. and Keller, U. and Landmesser, U. and Rassaf, T. and Anker, M.S. and Totzeck, M.
Cancers 13 (6): 1197. 10 March 2021

Recommendations for preclinical renal MRI: a comprehensive open-access protocol collection to improve training, reproducibility, and comparability of studies.
Pohlmann, A. and Back, S.J. and Fekete, A. and Friedli, I. and Hectors, S. and Jerome, N.P. and Ku, M.C. and Longo, D.L. and Meier, M. and Millward, J.M. and Periquito, J.S. and Seeliger, E. and Serai, S.D and Waiczies, S. and Sourbron, S. and Laustsen, C. and Niendorf, T.
Methods in Molecular Biology 2216 : 3-23. 2021

Essential practical steps for MRI of the kidney in experimental research.
Pohlmann, A. and Periquito, J.S. and Niendorf, T.
Methods in Molecular Biology 2216 : 349-367. 2021

Experimental protocol for MRI mapping of the blood oxygenation-sensitive parameters T(2)* and T(2) in the kidney.
Pohlmann, A. and Zhao, K. and Fain, S.B. and Prasad, P.V. and Niendorf, T.
Methods in Molecular Biology 2216 : 403-417. 2021

Fully phased human genome assembly without parental data using single-cell strand sequencing and long reads.
Porubsky, D. and Ebert, P. and Audano, P.A. and Vollger, M.R. and Harvey, W.T. and Marijon, P. and Ebler, J. and Munson, K.M. and Sorensen, M. and Sulovari, A. and Haukness, M. and Ghareghani, M. and Lansdorp, P.M. and Paten, B. and Devine, S.E. and Sanders, A.D. and Lee, C. and Chaisson, M.J.P. and Korbel, J.O. and Eichler, E.E. and Marschall, T.
Nature Biotechnology 39 (3): 302-308. March 2021

11,12-Epoxyeicosatrienoic acid-induced inhibition of FOXO factors promotes endothelial proliferation by down-regulating p27(Kip1).
Potente, M. and Fisslthaler, B. and Busse, R. and Fleming, I.
Journal of Biological Chemistry 278 (32): 29619-29625. 4 January 2021

Cytochrome P450 2C9-induced endothelial cell proliferation involves induction of mitogen-activated protein (MAP) kinase phosphatase-1, inhibition of the c-Jun N-terminal kinase, and up-regulation of cyclin D1.
Potente, M. and Michaelis, U.R. and Fisslthaler, B. and Busse, R. and Fleming, I.
Journal of Biological Chemistry 277 (18): 15671-15676. 4 January 2021

Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression.
Pott, F. and Postmus, D. and Brown, R.J.P. and Wyler, E. and Neumann, E. and Landthaler, M. and Goffinet, C.
Emerging Microbes & Infections 10 (1): 2151-2168. 16 November 2021

FRC-QE: a robust and comparable 3D microscopy image quality metric for cleared organoids.
Preusser, F. and Dos Santos, N. and Contzen, J. and Stachelscheid, H. and Costa, E.T. and Mergenthaler, P. and Preibisch, S.
Bioinformatics 37 (18): 3088-3090. 15 September 2021

In vivo detection of teriflunomide-derived fluorine signal during neuroinflammation using fluorine MR spectroscopy.
Prinz, C. and Starke, L. and Millward, J.M. and Fillmer, A. and Delgado, P.R. and Waiczies, H. and Pohlmann, A. and Rothe, M. and Nazaré, M. and Paul, F. and Niendorf, T. and Waiczies, S.
Theranostics 11 (6): 2490-2504. 1 January 2021

Pentafluorosulfanyl (SF(5)) as a superior (19)F magnetic resonance reporter group: signal detection and biological activity of teriflunomide derivatives.
Prinz, C. and Starke, L. and Ramspoth, T.F. and Kerkering, J. and Martos Riaño, V. and Paul, J. and Neuenschwander, M. and Oder, A. and Radetzki, S. and Adelhoefer, S. and Ramos Delgado, P. and Aravina, M. and Millward, J.M. and Fillmer, A. and Paul, F. and Siffrin, V. and von Kries, J.P. and Niendorf, T. and Nazaré, M. and Waiczies, S.
ACS Sensors 6 (11): 3948–3956. 26 November 2021

Cardiac phenotype and tissue sodium content in adolescents with defects in the melanocortin system.
Puder, L. and Roth, S. and Krabusch, P. and Wiegand, S. and Opitz, R. and Bald, M. and Flück, C. and Schulz, E. and Voss, E. and Markó, L. and Linz, P. and Berger, F. and Müller, D.N. and Kuehne, T. and Litt, M.J. and Cone, R.D. and Kühnen, P. and Kelm, M.
Journal of Clinical Endocrinology and Metabolism 106 (9): 2606–2616. September 2021

cDNA-detector: detection and removal of cDNA contamination in DNA sequencing libraries.
Qi, M. and Nayar, U. and Ludwig, L.S. and Wagle, N. and Rheinbay, E.
BMC Bioinformatics 22 (1): 611. 24 December 2021

YAP and β-catenin cooperate to drive oncogenesis in basal breast cancer.
Quinn, H.M. and Vogel, R. and Popp, O. and Mertins, P. and Lan, L. and Messerschmidt, C. and Landshammer, A. and Lisek, K. and Château-Joubert, S. and Marangoni, E. and Koren, E. and Fuchs, Y. and Birchmeier, W.
Cancer Research 81 (8): 2116-2127. April 2021

Therapeutic inhibition of RBM20 improves diastolic function in a murine heart failure model and human engineered heart tissue.
Radke, M.H. and Badillo-Lisakowski, V. and Britto-Borges, T. and Kubli, D.A. and Jüttner, R. and Parakkat, P. and Lopez Carballo, J. and Hüttemeister, J. and Liss, M. and Hansen, A. and Dieterich, C. and Mullick, A.E. and Gotthardt, M.
Science Translational Medicine 13 (622): eabe8952. December 2021

Integrated multi-omics analysis of RB-loss identifies widespread cellular programming and synthetic weaknesses.
Rajasekaran, S. and Siddiqui, J. and Rakijas, J. and Nicolay, B. and Lin, C. and Khan, E. and Patel, R. and Morris, R. and Wyler, E. and Boukhali, M. and Balasubramanyam, J. and Ranjith Kumar, R. and Van Rechem, C. and Vogel, C. and Elchuri, S.V. and Landthaler, M. and Obermayer, B. and Haas, W. and Dyson, N. and Miles, W.
Communications Biology 4 (1): 977. 17 August 2021

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.
Ramberger, E. and Sapozhnikova, V. and Kowenz-Leutz, E. and Zimmermann, K. and Nicot, N. and Nazarov, P.V. and Perez-Hernandez, D. and Reimer, U. and Mertins, P. and Dittmar, G. and Leutz, A.
iScience 24 (6): 102686. 25 June 2021

A universal peptide matrix interactomics approach to disclose motif dependent protein binding.
Ramberger, E. and Suarez-Artiles, L. and Perez-Hernandez, D. and Haji, M. and Popp, O. and Reimer, U. and Leutz, A. and Dittmar, G. and Mertins, P.
Molecular & Cellular Proteomics 20 : 100135. 13 August 2021

Expanding the phenotype of NUP85 mutations beyond nephrotic syndrome to primary autosomal recessive microcephaly and Seckel syndrome spectrum disorders.
Ravindran, E. and Jühlen, R. and Vieira-Vieira, C.H. and Ha, T. and Salzberg, Y. and Fichtman, B. and Luise-Becker, L. and Martins, N. and Picker-Minh, S. and Bessa, P. and Arts, P. and Jackson, M.R. and Taranath, A. and Kamien, B. and Barnett, C. and Li, N. and Tarabykin, V. and Stoltenburg-Didinger, G. and Harel, A. and Selbach, M. and Dickmanns, A. and Fahrenkrog, B. and Hu, H. and Scott, H. and Kaindl, A.M.
Human Molecular Genetics 30 (22): 2068-2081. 15 November 2021

Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma.
Regina, C. and Hamed, E. and Andrieux, G. and Angenendt, S. and Schneider, M. and Ku, M. and Follo, M. and Wachtel, M. and Ke, E. and Kikuchi, K. and Henssen, A.G. and Schäfer, B.W. and Boerries, M. and Wagers, A.J. and Keller, C. and Hettmer, S.
Life Science Alliance 4 (9): e202001002. September 2021

Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
Reimann, M. and Schrezenmeier, J.F. and Richter-Pechanska, P. and Dolnik, A. and Hick, T.P. and Schleich, K. and Cai, X. and Fan, D.N.Y. and Lohneis, P. and Masswig, S. and Denker, S. and Busse, A. and Knittel, G. and Flümann, R. and Childs, D. and Childs, L. and Gätjens-Sanchez, A.M. and Bullinger, L. and Rosenwald, A. and Reinhardt, H.C. and Schmitt, C.A.
Blood 137 (20): 2785-2899. 20 May 2021

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Ren, A.A. and Snellings, D.A. and Su, Y.S. and Hong, C.C. and Castro, M. and Tang, A.T. and Detter, M.R. and Hobson, N. and Girard, R. and Romanos, S. and Lightle, R. and Moore, T. and Shenkar, R. and Benavides, C. and Beaman, M.M. and Mueller-Fielitz, H. and Chen, M. and Mericko, P. and Yang, J. and Sung, D.C. and Lawton, M.T. and Ruppert, M. and Schwaninger, M. and Körbelin, J. and Potente, M. and Awad, I.A. and Marchuk, D.A. and Kahn, M.L.
Nature 594 (7862): :271-276. 10 June 2021

A sweet story of metabolic innovation in the naked mole-rat.
Reznick, J. and Park, T.J. and Lewin, G.R.
Advances in Experimental Medicine and Biology 1319 (1319): 271-286. 24 August 2021

Subsegmentation of the kidney in experimental MR images using morphology-based regions-of-interest or multiple-layer concentric objects.
Riazy, L. and Milani, B. and Periquito, J.S. and Cantow, K. and Niendorf, T. and Pruijm, M. and Seeliger, E. and Pohlmann, A.
Methods in Molecular Biology 2216 : 549-564. 2021

Capecitabine in combination with bendamustine in pretreated women with HER2-negative metastatic breast cancer: results of a phase II trial (AGMT MBC-6).
Rinnerthaler, G. and Gampenrieder, S.P. and Petzer, A. and Hubalek, M. and Petru, E. and Sandholzer, M. and Andel, J. and Balic, M. and Melchardt, T. and Hauser-Kronberger, C. and Schmitt, C.A. and Ulmer, H. and Greil, R.
Therapeutic Advances in Medical Oncology 13 : 17588359211042301. 19 October 2021

COVID-19: a simple statistical model for predicting intensive care unit load in exponential phases of the disease.
Ritter, M. and Ott, D.V.M. and Paul, F. and Haynes, J.D. and Ritter, K.
Scientific Reports 11 (1): 5018. 3 March 2021

Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine.
Rivera, M. and Fichtner, I. and Wulf-Goldenberg, A. and Sers, C. and Merk, J. and Patone, G. and Alp, K.M. and Kanashova, T. and Mertins, P. and Hoffmann, J. and Stein, U. and Walther, W.
Neoplasia 23 (1): 21-35. January 2021

Foveal changes in aquaporin‐4 antibody seropositive neuromyelitis optica spectrum disorder are independent of optic neuritis and not overtly progressive.
Roca-Fernández, A. and Oertel, F.C. and Yeo, T and Motamedi, S. and Probert, F. and Craner, M.J. and Sastre-Garriga, J. and Zimmermann, H.G. and Asseyer, S. and Kuchling, J. and Bellmann-Strobl, J. and Ruprecht, K. and Leite, M.I. and Paul, F. and Brandt, A.U. and Palace, J.
European Journal of Neurology 28 (7): 2280-2293. July 2021

Increased angiotensin II formation in the brain modulates cardiovascular homeostasis and erythropoiesis.
Rodrigues, A.F. and Todiras, M. and Qadri, F. and Campagnole-Santos, M.J. and Alenina, N. and Bader, M.
Clinical Science 135 (11): 1353-1367. 2 June 2021

A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions.
Rodríguez de los Santos, M. and Rivalan, M. and David, F.S. and Stumpf, A. and Pitsch, J. and Tsortouktzidis, D. and Velasquez, L.M. and Voigt, A. and Schilling, K. and Mattei, D. and Long, M. and Vogt, G. and Knaus, A. and Fischer-Zirnsak, B. and Wittler, L. and Timmermann, B. and Robinson, P.N. and Horn, D. and Mundlos, S. and Kornak, U. and Becker, A.J. and Schmitz, D. and Winter, Y. and Krawitz, P.M.
Proceedings of the National Academy of Sciences of the United States of America 118 (2): e2014481118. 12 January 2021

Combined inhibition of Aurora-A and ATR kinases results in regression of MYCN-amplified neuroblastoma.
Roeschert, I. and Poon, E. and Henssen, A.G. and Dorado Garcia, H. and Gatti, M. and Giansanti, C. and Jamin, Y. and Ade, C.P. and Gallant, P. and Schülein-Völk, C. and Beli, P. and Richards, M. and Rosenfeldt, M. and Altmeyer, M. and Anderson, J. and Eggert, A. and Dobbelstein, M. and Bayliss, R. and Chesler, L. and Büchel, G. and Eilers, M.
Nature Cancer 2 (3): 312-326. March 2021

Validation of computer-adaptive contrast sensitivity as a tool to assess visual impairment in multiple sclerosis patients.
Rosenkranz, S.C. and Kaulen, B. and Zimmermann, H.G. and Bittner, A.K. and Dorr, M. and Stellmann, J.P.
Frontiers in Neuroscience 15 : 591302. 23 February 2021

A versatile sub-nanomolar fluorescent ligand enables NanoBRET binding studies and single-molecule microscopy at the histamine H(3) receptor.
Rosier, N. and Grätz, L. and Schihada, H. and Möller, J. and Işbilir, A. and Humphrys, L.J. and Nagl, M. and Seibel, U. and Lohse, M.J. and Pockes, S.
Journal of Medicinal Chemistry 64 (15): 11695-11708. 12 August 2021

Chromothripsis followed by circular recombination drives oncogene amplification in human cancer.
Rosswog, C. and Bartenhagen, C. and Welte, A. and Kahlert, Y. and Hemstedt, N. and Lorenz, W. and Cartolano, M. and Ackermann, S. and Perner, S. and Vogel, W. and Altmüller, J. and Nürnberg, P. and Hertwig, F. and Göhring, G. and Lilienweiss, E. and Stütz, A.M. and Korbel, J.O. and Thomas, R.K. and Peifer, M. and Fischer, M.
Nature Genetics 53 (12): 1673–1685. December 2021

EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells.
Roy, S. and Rizvi, Z.A. and Clarke, A.J. and Macdonald, F. and Pandey, A. and Zaiss, D.M.W. and Simon, A.K. and Awasthi, A.
Nature Communications 12 (1): 3182. 1 June 2021

Compendium of 530 metagenome-assembled bacterial and archaeal genomes from the polar Arctic Ocean.
Royo-Llonch, M. and Sánchez, P. and Ruiz-González, C. and Salazar, G. and Pedrós-Alió, C. and Sebastián, M. and Labadie, K. and Paoli, L. and M. Ibarbalz, F. and Zinger, L. and Churcheward, B. and Chaffron, S. and Eveillard, D. and Karsenti, E. and Sunagawa, S. and Wincker, P. and Karp-Boss, L. and Bowler, C. and Acinas, S.G.
Nature Microbiology 6 (12): 1561-1574. December 2021

Probabilistic deep learning for instance segmentation.
Rumberger, J.L. and Mais, L. and Kainmueller, D.
Lecture Notes in Computer Science 12535 : 445-457. 2021

Epigallocatechin gallate in progressive MS: a randomized, placebo-controlled trial.
Rust, R. and Chien, C. and Scheel, M. and Brandt, A.U. and Dörr, J. and Wuerfel, J. and Klumbies, K. and Zimmermann, H. and Lorenz, M. and Wernecke, K.D. and Bellmann-Strobl, J. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 8 (3): e964. May 2021

Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7-related osteopetrosis.
Rössler, U. and Hennig, A.F. and Stelzer, N. and Bose, S. and Kopp, J. and Søe, K. and Cyganek, L. and Zifarelli, G. and Ali, S. and von der Hagen, M. and Strässler, E.T. and Hahn, G. and Pusch, M. and Stauber, T. and Izsvák, Z. and Gossen, M. and Stachelscheid, H. and Kornak, U.
Journal of Bone and Mineral Research 36 (8): 1621-1635. August 2021

Three-dimensional superresolution fluorescence microscopy maps the variable molecular architecture of the nuclear pore complex.
Sabinina, V.J. and Hossain, M.J. and Hériché, J.K. and Hoess, P. and Nijmeijer, B. and Mosalaganti, S. and Kueblbeck, M. and Callegari, A. and Szymborska, A. and Beck, M. and Ries, J. and Ellenberg, J.
Molecular Biology of the Cell 32 (17): 1523-1533. 15 August 2021

Is LRP2 involved in leptin transport over the blood-brain barrier and development of obesity?
Sandin, E.S. and Folberth, J. and Müller-Fielitz, H. and Pietrzik, C.U. and Herold, E. and Willnow, T.E. and Pfluger, P.T. and Nogueiras, R. and Prevot, V. and Krey, T. and Schwaninger, M.
International Journal of Molecular Sciences 22 (9): 4998. 8 May 2021

Career advancement for women in diabetes-related research: developing and retaining female talent.
Sandoval, D.A. and Alonso, L.C. and Gannon, M. and Sander, M. and Sussel, L. and Reusch, J.E.B.
Diabetes 70 (8): 1634-1637. 1 August 2021

Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer.
Schaufler, D. and Ast, D.F. and Tumbrink, H.L. and Abedpour, N. and Maas, L. and Schwäbe, A.E. and Spille, I. and Lennartz, S. and Fassunke, J. and Aldea, M. and Besse, B. and Planchard, D. and Nogova, L. and Michels, S. and Kobe, C. and Persigehl, T. and Westphal, T. and Koleczko, S. and Fischer, R. and Weber, J.P. and Altmüller, J. and Thomas, R.K. and Merkelbach-Bruse, S. and Gautschi, O. and Mezquita, L. and Büttner, R. and Wolf, J. and Peifer, M. and Brägelmann, J. and Scheffler, M. and Sos, M.L.
npj Precision Oncology 5 (1): 102. 17 December 2021

The effect of adjuvant therapies on long-term outcome for primary resected synovial sarcoma in a series of mainly children and adolescents.
Scheer, M. and Vokuhl, C. and Bauer, S. and Fuchs, J. and Loff, S. and Timmermann, B. and Münter, M. and Henssen, A.G. and Kazanowska, B. and Niggli, F. and Ladenstein, R. and Ljungman, G. and Koscielniak, E. and Klingebiel, T.
Journal of Cancer Research and Clinical Oncology 147 (12): 3735-3747. December 2021

Reduction of cortical parvalbumin expressing GABAergic interneurons in a rodent hyperoxia model of preterm birth brain injury with deficits in social behavior and cognition.
Scheuer, T. and Auf dem Brinke, E. and Grosser, S. and Wolf, S.A. and Mattei, D. and Sharkovska, Y. and Barthel, P.C. and Endesfelder, S. and Friedrich, V. and Bührer, C. and Vida, I. and Schmitz, T.
Development 148 (20): dev.198390. October 2021

Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ejection fraction.
Schiattarella, G.G. and Altamirano, F. and Kim, S.Y. and Tong, D. and Ferdous, A. and Piristine, H. and Dasgupta, S. and Wang, X. and French, K.M. and Villalobos, E. and Spurgin, S.B. and Waldman, M. and Jiang, N. and May, H.I. and Hill, T.M. and Luo, Y. and Yoo, H. and Zaha, V.G. and Lavandero, S. and Gillette, T.G. and Hill, J.A.
Nature Communications 12 (1): 1684. 16 March 2021

Bioluminescence in G protein-coupled receptors drug screening using nanoluciferase and halo-tag technology.
Schihada, H. and Nemec, K. and Lohse, M.J. and Maiellaro, I.
Methods in Molecular Biology 2268 : 137-147. 2021

Hypo- und Hypernatriämien auf der Intensivstation : Fallstricke des Volumenmanagements [Hypo- and hypernatremia in the intensive care unit : pitfalls in volume management].
Schilling, J. and Compton, F. and Schmidt-Ott, K.
Medizinische Klinik, Intensivmedizin und Notfallmedizin 116 : 672-677. November 2021

Small, seeding-competent huntingtin fibrils are prominent aggregate species in brains of zQ175 Huntington's disease knock-in mice.
Schindler, F. and Praedel, N. and Neuendorf, N. and Kunz, S. and Schnoegl, S. and Mason, M.A. and Taxy, B.A. and Bates, G.P. and Khoshnan, A. and Priller, J. and Grimm, J. and Maier, M. and Boeddrich, A. and Wanker, E.E.
Frontiers in Neuroscience 15 : 682172. 22 June 2021

Serum GFAP and NfL as disease severity and prognostic biomarkers in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder.
Schindler, P. and Grittner, U. and Oechtering, J. and Leppert, D. and Siebert, N. and Duchow, A.S. and Oertel, F.C. and Asseyer, S. and Kuchling, J. and Zimmermann, H.G. and Brandt, A.U. and Benkert, P. and Reindl, M. and Jarius, S. and Paul, F. and Bellmann-Strobl, J. and Kuhle, J. and Ruprecht, K.
Journal of Neuroinflammation 18 (1): 105. 1 May 2021

Modeling chemotherapy induced neurotoxicity with human induced pluripotent stem cell (iPSC)-derived sensory neurons.
Schinke, C. and Vallone, V.F. and Ivanov, A. and Peng, Y. and Körtvelyessy, P. and Nolte, L. and Huehnchen, P. and Beule, D. and Stachelscheid, H. and Boehmerle, W. and Endres, M.
Neurobiology of Disease 155 : 105391. July 2021

mTOR-activating mutations in RRAGD are causative for kidney tubulopathy and cardiomyopathy.
Schlingmann, K.P. and Jouret, F. and Shen, K. and Nigam, A. and Arjona, F. and Dafinger, C. and Houillier, P. and Jones, D. and Kleinerüschkamp, F. and Oh, J. and Godefroid, N. and Eltan, M. and Güran, T. and Burtey, S. and Parotte, M.C. and König, J. and Braun, A. and Bos, C. and Serra, M.I. and Rehmann, H. and Zwartkruis, F. and Renkema, K. and Klingel, K. and Schulze-Bahr, E. and Schermer, B. and Bergmann, C. and Altmüller, J. and Thiele, H. and Beck, B. and Dahan, K. and Sabatini, D. and Liebau, M. and Vargas-Poussou, R. and Knoers, N. and Konrad, M. and de Baaij, J.
Journal of the American Society of Nephrology 32 (11): 2885-2899. November 2021

Netboost: boosting-supported network analysis improves high-dimensional omics prediction in acute myeloid leukemia and Huntington's disease.
Schlosser, P. and Knaus, J. and Schmutz, M. and Döhner, K. and Plass, C. and Bullinger, L. and Claus, R. and Binder, H. and Lübbert, M. and Schumacher, M.
IEEE/ACM Transactions on Computational Biology and Bioinformatics 18 (6): 2635-2648. 1 November 2021

Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.
Schmalbrock, L.K. and Dolnik, A. and Cocciardi, S. and Sträng, E. and Theis, F. and Jahn, N. and Panina, E. and Blätte, T.J. and Herzig, J.K. and Skambraks, S. and Rücker, F.G. and Gaidzik, V.I. and Paschka, P. and Fiedler, W. and Salih, H.R. and Wulf, G.G. and Schroeder, T. and Lübbert, M. and Schlenk, R.F. and Thol, F. and Heuser, M. and Larson, R.A. and Ganser, A. and Stunnenberg, H.G. and Minucci, S. and Stone, R.M. and Bloomfield, C.D. and Döhner, H. and Döhner, K. and Bullinger, L.
Blood 137 (22): 3093-3104. 3 June 2021

Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions.
Schmelz, K. and Toedling, J. and Huska, M. and Cwikla, M.C. and Kruetzfeldt, L.M. and Proba, J. and Ambros, P.F. and Ambros, I.M. and Boral, S. and Lodrini, M. and Chen, C.Y. and Burkert, M. and Guergen, D. and Szymansky, A. and Astrahantseff, K. and Kuenkele, A. and Haase, K. and Fischer, M. and Deubzer, H.E. and Hertwig, F. and Hundsdoerfer, P. and Henssen, A.G. and Schwarz, R.F. and Schulte, J.H. and Eggert, A.
Nature Communications 12 (1): 6804. 23 November 2021

Anti-aquaporin 4 IgG is not associated with any clinical disease characteristics in Neuromyelitis Optica Spectrum Disorder.
Schmetzer, O. and Lakin, E. and Roediger, B. and Duchow, A. and Asseyer, S. and Paul, F. and Siebert, N.
Frontiers in Neurology 12 : 635419. 12 March 2021

Biallelic variants in YRDC cause a developmental disorder with progeroid features.
Schmidt, J. and Goergens, J. and Pochechueva, T. and Kotter, A. and Schwenzer, N. and Sitte, M. and Werner, G. and Altmueller, J. and Thiele, H. and Nürnberg, P. and Isensee, J. and Li, Y. and Müller, C. and Leube, B. and Reinhardt, H.C. and Hucho, T. and Salinas, G. and Helm, M. and Jachimowicz, R.D. and Wieczorek, D. and Kohl, T. and Lehnart, S.E. and Yigit, G. and Wollnik, B.
Human Genetics 140 (12): 1679-1693. December 2021

Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis.
Schmidt, O. and Nehls, N. and Prexler, C. and von Heyking, K. and Groll, T. and Pardon, K. and Garcia, H.D. and Hensel, T. and Gürgen, D. and Henssen, A.G. and Eggert, A. and Steiger, K. and Burdach, S. and Richter, G.H.S.
Journal of Experimental & Clinical Cancer Research 40 (1): 322. 15 October 2021

Large farm animals used for research purposes: a survey on purchase, housing and hygiene management.
Schmidt, T. and Ferrara, F. and Pobloth, A.M. and Jeuthe, S.
Animals 11 (8): 2158. August 2021

SORLA is required for insulin-induced expansion of the adipocyte precursor pool in visceral fat.
Schmidt, V. and Horváth, C. and Dong, H. and Blüher, M. and Qvist, P. and Wolfrum, C. and Willnow, T.E.
Journal of Cell Biology 220 (12): e202006058. 6 December 2021

Akute Nierenschädigung - Update 2021 [Acute kidney injury - update 2021].
Schmidt-Ott, K.M.
Deutsche Medizinische Wochenschrift 146 (15): 988-993. August 2021

TFE3 activation in a TSC1-altered malignant PEComa: challenging the dichotomy of the underlying pathogenic mechanisms.
Schmiester, M. and Dolnik, A. and Kornak, U. and Pfitzner, B. and Hummel, M. and Treue, D. and Hartmann, A. and Agaimy, A. and Weyerer, V. and Lekaj, A. and Brakemeier, S. and Peters, R. and Öllinger, R. and Märdian, S. and Bullinger, L. and Striefler, J.K. and Flörcken, A.
Journal of Pathology Clinical Research 7 (1): 3-9. January 2021

Phenotypic mapping of pathologic cross-talk between glioblastoma and innate immune cells by synthetic genetic tracing.
Schmitt, M.J. and Company, C. and Dramaretska, Y. and Barozzi, I. and Göhrig, A. and Kertalli, S. and Großmann, M. and Naumann, H. and Sánchez-Bailón, M.P. and Hulsman, D. and Glass, R. and Squatrito, M. and Serresi, M. and Gargiulo, G.
Cancer Discovery 11 (3): 754-777. March 2021

A randomized phase 3 trial of autologous vs allogeneic transplantation as part of first-line therapy in poor-risk peripheral T-NHL.
Schmitz, N. and Truemper, L.H. and Bouabdallah, K. and Ziepert, M. and Leclerc, M. and Cartron, G. and Jaccard, A. and Reimer, P. and Wagner-Drouet, E.M. and Wilhelm, M. and Sanhes, L. and Lamy, T. and de Leval, L. and Rosenwald, A. and Roussel, M. and Kroschinsky, F.P. and Lindemann, W.W. and Dreger, P. and Viardot, A. and Milpied, N.J. and Gisselbrecht, C. and Wulf, G.G. and Gyan, E. and Gaulard, P. and Bay, J.O. and Glass, B. and Poeschel, V. and Damaj, G. and Sibon, D. and Delmer, A.J. and Bilger, K. and Banos, A. and Haenel, M. and Dreyling, M. and Metzner, B. and Keller, U. and Braulke, F. and Friedrichs, B. and Nickelsen, M. and Altmann, B. and Tournilhac, O.
Blood 137 (19): 2646-2656. 13 May 2021

Spinocerebellar ataxia type 14: refining clinicogenetic diagnosis in a rare adult-onset disorder.
Schmitz-Hübsch, T. and Lux, S. and Bauer, P. and Brandt, A.U. and Schlapakow, E. and Greschus, S. and Scheel, M. and Gärtner, H. and Kirlangic, M.E. and Gras, Vi. and Timmann, D. and Synofzik, M. and Giorgetti, A. and Carloni, P. and Shah, J.N. and Schöls, L. and Kopp, U. and Bußenius, L. and Oberwahrenbrock, T. and Zimmermann, H. and Pfueller, C. and Kadas, E.M. and Rönnefarth, M. and Grosch, A.S. and Endres, M. and Amunts, K. and Paul, F. and Doss, S. and Minnerop, M.
Annals of Clinical and Translational Neurology 8 (4): 774-789. April 2021

Multifunctional RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes.
Schneider-Lunitz, V. and Ruiz-Orera, J. and Hubner, N. and van Heesch, S.
PLoS Computational Biology 17 (12): e1009658. 8 December 2021

On the adhesion-velocity relation and length adaptation of motile cells on stepped fibronectin lanes.
Schreiber, C. and Amiri, B. and Heyn, J.C.J. and Rädler, J.O. and Falcke, M.
Proceedings of the National Academy of Sciences of the United States of America 118 (4): e2009959118. 26 January 2021

Heterozygous truncating variants in SUFU cause congenital ocular motor apraxia.
Schröder, S. and Li, Y. and Yigit, G. and Altmüller, J. and Bader, I. and Bevot, A. and Biskup, S. and Dreha-Kulaczewski, S. and Korenke, C.G. and Kottke, R. and Mayr, J.A. and Preisel, M. and Toelle, S.P. and Wente-Schulz, S. and Wortmann, S.B. and Hahn, H. and Boltshauser, E. and Uhmann, A. and Wollnik, B. and Brockmann, K.
Genetics in Medicine 23 (2): 341-351. February 2021

Reduced systolic function and not genetic variants determine outcome in pediatric and adult left ventricular noncompaction cardiomyopathy.
Schultze-Berndt, A. and Kühnisch, J. and Herbst, C. and Seidel, F. and Al-Wakeel-Marquard, N. and Dartsch, J. and Theisen, S. and Knirsch, W. and Jenni, R. and Greutmann, M. and Oechslin, E. and Berger, F. and Klaassen, S.
Frontiers in Pediatrics 9 : 722926. September 2021

USH2A is a Meissner's corpuscle protein necessary for normal vibration sensing in mice and humans.
Schwaller, F. and Bégay, V. and García-García, G. and Taberner, F.J. and Moshourab, R. and McDonald, B. and Docter, T. and Kühnemund, J. and Ojeda-Alonso, J. and Paricio-Montesinos, R. and Lechner, S.G. and Poulet, J.F.A. and Millan, J.M. and Lewin, G.R.
Nature Neuroscience 24 (1): 74-81. January 2021

Fingolimod therapy in multiple sclerosis leads to the enrichment of a subpopulation of aged NK cells.
Schwichtenberg, S.C. and Wisgalla, A. and Schroeder-Castagno, M. and Alvarez-González, C. and Schlickeiser, S. and Siebert, N. and Bellmann-Strobl, J. and Wernecke, K.D. and Paul, F. and Dörr, J. and Infante-Duarte, C.
Neurotherapeutics 18 (3): 1783-1797. July 2021

Diabetic pregnancy as a novel risk factor for cardiac dysfunction in the offspring-the heart as a target for fetal programming in rats.
Schütte, T. and Kedziora, S.M. and Haase, N. and Herse, F. and Alenina, N. and Müller, D.N. and Bader, M. and Schupp, M. and Dechend, R. and Golic, M. and Kräker, K.
Diabetologia 64 (12): 2829-2842. December 2021

Intrauterine exposure to diabetic milieu does not induce diabetes and obesity in male adulthood in a novel rat model.
Schütte, T. and Kedziora, S.M. and Haase, N. and Herse, F. and Busjahn, A. and Birukov, A. and Alenina, N. and Müller, D.N. and Bader, M. and Schupp, M. and Dechend, R. and Kräker, K. and Golic, M.
Hypertension 77 (1): 202-215. January 2021

The role and uses of antibodies in COVID-19 infections: a living review.
Scourfield, D.C. and Reed, S.G. and Quastel, M. and Alderson, J. and Bart, V.M.T. and Teijeira Crespo, A. and Jones, R. and Pring, E. and Richter, F.C. and Burnell, S.E.A.
Oxford Open Immunology 2 (1): iqab003. 28 January 2021

CellFIE: CRISPR- and cell fusion-based two-hybrid interaction mapping of endogenous proteins.
Secker, C. and Kostova, S. and Niederlechner, H. and Beetz, S. and Wendland, I. and Liebich, M.J. and Polzer, O. and Groh, M. and Schnoegl, S. and Trepte, P. and Wanker, E.E.
Journal of Molecular Biology 433 (24): 167305. 3 December 2021

Enhanced Ca(2+) signaling, mild primary aldosteronism, and hypertension in a familial hyperaldosteronism mouse model (Cacna1h(M1560V/+)).
Seidel, E. and Schewe, J. and Zhang, J. and Dinh, H.A. and Forslund, S.K. and Markó, L. and Hellmig, N. and Peters, J. and Muller, D.N. and Lifton, R.P. and Nottoli, T. and Stölting, G. and Scholl, U.I.
Proceedings of the National Academy of Sciences of the United States of America 118 (17): e2014876118. 27 April 2021

Pathogenic variants associated with dilated cardiomyopathy predict outcome in pediatric myocarditis.
Seidel, F. and Holtgrewe, M. and Al-Wakeel-Marquard, N. and Opgen-Rhein, B. and Dartsch, J. and Herbst, C. and Beule, D. and Pickardt, T. and Klingel, K. and Messroghli, D. and Berger, F. and Schubert, S. and Kühnisch, J. and Klaassen, S.
Circulation Genomic and Precision Medicine 14 (4): e003250. 4 August 2021

TUNAR lncRNA encodes a microprotein that regulates neural differentiation and neurite formation by modulating calcium dynamics.
Senís, E. and Esgleas, M. and Najas, S. and Jiménez-Sábado, V. and Bertani, C. and Giménez-Alejandre, M. and Escriche, A. and Ruiz-Orera, J. and Hergueta-Redondo, M. and Jiménez, M. and Giralt, A. and Nuciforo, P. and Albà, M.M. and Peinado, H. and Del Toro, D. and Hove-Madsen, L. and Götz, M. and Abad, M.
Frontiers in Cell and Developmental Biology 9 : 747667. 31 December 2021

Functional antagonism of chromatin modulators regulates epithelial-mesenchymal transition.
Serresi, M. and Kertalli, S. and Li, L. and Schmitt, M.J. and Dramaretska, Y. and Wierikx, J. and Hulsman, D. and Gargiulo, G.
Science Advances 7 (9): eabd7974. 24 February 2021

Polysialic acid in the rat brainstem and thoracolumbar spinal cord: distribution, cellular location and comparison with mouse.
Shahbazian, S. and Bokiniec, P. and Berning, B.A. and McMullan, S. and Goodchild, A.K.
Journal of Comparative Neurology 529 (4): 811-827. March 2021

Structural and functional characterization of allatostatin receptor type-C of Thaumetopoea pityocampa, a potential target for next-generation pest control agents.
Shahraki, A. and Işbilir, A. and Dogan, B. and Lohse, M.J. and Durdagi, S. and Birgul-Iyison, N.
Journal of Chemical Information and Modeling 61 (2): 715-728. 22 February 2021

Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain.
Sheinman, M. and Arkhipova, K. and Arndt, P.F. and Dutilh, B.E. and Hermsen, R. and Massip, F.
eLife 10 : e62719. 9 July 2021

Enduring effects of conditional brain serotonin knockdown, followed by recovery, on adult rat neurogenesis and behavior.
Sidorova, M. and Kronenberg, G. and Matthes, S. and Petermann, M. and Hellweg, R. and Tuchina, O. and Bader, M. and Alenina, N. and Klempin, F.
Cells 10 (11): 3240. 19 November 2021

Inebilizumab in AQP4-Ab-positive neuromyelitis optica spectrum disorder.
Siebert, N. and Duchow, A. and Paul, F. and Infante-Duarte, C. and Bellmann-Strobl, J.
Drugs of Today 57 (5): 321-336. May 2021

Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge.
Sieberts, S.K. and Schaff, J. and Duda, M. and Pataki, B.Á. and Sun, M. and Snyder, P. and Daneault, J.F. and Parisi, F. and Costante, G. and Rubin, U. and Banda, P. and Chae, Y. and Chaibub Neto, E. and Dorsey, E.R. and Aydın, Z. and Chen, A. and Elo, L.L. and Espino, C. and Glaab, E. and Goan, E. and Golabchi, F.N. and Görmez, Y. and Jaakkola, M.K. and Jonnagaddala, J. and Klén, R. and Li, D. and McDaniel, C. and Perrin, D. and Perumal, T.M. and Rad, N.M. and Rainaldi, E. and Sapienza, S. and Schwab, P. and Shokhirev, N. and Venäläinen, M.S. and Vergara-Diaz, G. and Zhang, Y. and Wang, Y. and Guan, Y. and Brunner, D. and Bonato, P. and Mangravite, L.M. and Omberg, L.
NPJ Digital Medicine 4 (1): 53. 19 March 2021

Contribution of tissue inflammation and blood-brain barrier disruption to brain softening in a mouse model of multiple sclerosis.
Silva, R.V. and Morr, A.S. and Mueller, S. and Koch, S.P. and Boehm-Sturm, P. and Rodriguez-Sillke, Y. and Kunkel, D. and Tzschätzsch, H. and Kühl, A.A. and Schnorr, J. and Taupitz, M. and Sack, I. and Infante-Duarte, C.
Frontiers in Neuroscience 15 : 701308. August 2021

Chances and challenges of registry-based pharmacovigilance in multiple sclerosis: lessons learnt from the implementation of the multicenter REGIMS registry.
Simbrich, A. and Thibaut, J. and Khil, L. and Maximov, S. and Wiendl, H. and Berger, K.
Drug Safety 44 (1): 7-15. January 2021

New insights on Phyllanthus reticulatus Poir. leaves and stem bark extracts: UPLC-ESI-TOF-MS profiles, and biopharmaceutical and in silico analysis.
Sinan, K.I. and de la Luz Cádiz-Gurrea, M. and Javier Leyva-Jiménez, F. and Fernández-Ochoa, Á. and Segura-Carretero, A. and Glamocilja, J. and Sokovic, M. and Nenadić, M. and Aktumsek, A. and Dall'Acqua, S. and Zengin, G.
New Journal of Chemistry 45 (45): 21049-21065. 7 December 2021

SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells.
Singh, Y. and Trautwein, C. and Fendel, R. and Krickeberg, N. and Berezhnoy, G. and Bissinger, R. and Ossowski, S. and Salker, M.S. and Casadei, N. and Riess, O.
Heliyon 7 (6): e07147. June 2021

EACVI survey on the evaluation of left ventricular diastolic function.
Sitges, M. and Ajmone Marsan, N. and Cameli, M. and D'Andrea, A. and Carvalho, R.F. and Holte, E. and Michalski, B. and Podlesnikar, T. and Popescu, B.A. and Schulz-Menger, J. and Stankovic, I. and Haugaa, K.H. and Dweck, M.R.
European Heart Journal - Cardiovascular Imaging 22 (10): 1098-1105. October 2021

Regional specialization and fate specification of bone stromal cells in skeletal development.
Sivaraj, K.K. and Jeong, H.W. and Dharmalingam, B. and Zeuschner, D. and Adams, S. and Potente, M. and Adams, R.H.
Cell Reports 36 (2): 109352. 13 July 2021

Interplay of diverse adjuvants and nanoparticle presentation of native-like HIV-1 envelope trimers.
Sliepen, K. and Schermer, E. and Bontjer, I. and Burger, J.A. and Lévai, R.F. and Mundsperger, P. and Brouwer, P.J.M. and Tolazzi, M. and Farsang, A. and Katinger, D. and Moore, J.P. and Scarlatti, G. and Shattock, R.J. and Sattentau, Q.J. and Sanders, R.W.
NPJ Vaccines 6 (1): 103. 17 August 2021

Depletion of cardiac cardiolipin synthase alters systolic and diastolic function.
Smeir, E. and Leberer, S. and Blumrich, A. and Vogler, G. and Vasiliades, A. and Dresen, S. and Jaeger, C. and Gloaguen, Y. and Klose, C. and Beule, D. and Schulze, P.C. and Bodmer, R. and Foryst-Ludwig, A. and Kintscher, U.
iScience 24 (11): 103314. 19 November 2021

The Asian and African/Caribbean AQP4-NMOSD patient outcomes according to self-identified race and place of residence.
Soares-dos-Reis, R. and Tsz-Ching, J.L. and Kim, S.H. and Jacob, A. and Whittam, D. and Berthelot, E. and Paul, F. and Nakashima, I. and Tye, J.S.N. and De Seze, J. and Jitprapaikulsan, J. and Tan, K. and Yang, L. and Elsone, L. and Leite, M.I. and Mealy, M.A. and Levy, M. and Fan, M. and Siebert, N. and Asgari, N. and Cabre, P. and Siritho, S. and Pittock, S.J. and Wing-Ho, S.C. and Senger, T. and Yeo, T. and Takai, Y. and Pandit, L. and Kim, H.J. and Palace, J.
Multiple Sclerosis and Related Disorders 53 : 103080. August 2021

In-depth cell-free DNA sequencing reveals genomic landscape of Hodgkin’s lymphoma and facilitates ultrasensitive residual disease detection.
Sobesky, S. and Mammadova, L. and Cirillo, M. and Drees, E.E.E. and Mattlener, J. and Dörr, H. and Altmüller, J. and Shi, Z. and Bröckelmann, P.J. and Weiss, J. and Kreissl, S. and Sasse, S. and Ullrich, R.T. and Reinke, S. and Klapper, W. and Gerhard-Hartmann, E. and Rosenwald, A. and Roemer, M.G.M. and Nürnberg, P. and Hagenbeek, A. and Zijlstra, J.M. and Pegtel, D.M. and Engert, A. and Borchmann, P. and von Tresckow, B. and Borchmann, S.
Med 2 (10): 1171-1193. 8 October 2021

HMGB1 coordinates SASP-related chromatin folding and RNA homeostasis on the path to senescence.
Sofiadis, K. and Josipovic, N. and Nikolic, M. and Kargapolova, Y. and Übelmesser, N. and Varamogianni-Mamatsi, V. and Zirkel, A. and Papadionysiou, I. and Loughran, G. and Keane, J. and Michel, A. and Gusmao, E.G. and Becker, C. and Altmüller, J. and Georgomanolis, T. and Mizi, A. and Papantonis, A.
Molecular Systems Biology 17 (6): e9760. 1 June 2021

Oxidized LDL-dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy.
Sommariva, E. and Stadiotti, I. and Casella, M. and Catto, V. and Dello Russo, A. and Carbucicchio, C. and Arnaboldi, L. and De Metrio, S. and Milano, G. and Scopece, A. and Casaburo, M. and Andreini, D. and Mushtaq, S. and Conte, E. and Chiesa, M. and Birchmeier, W. and Cogliati, E. and Paolin, A. and König, E. and Meraviglia, V. and De Musso, M. and Volani, C. and Cattelan, G. and Rauhe, W. and Turnu, L. and Porro, B. and Pedrazzini, M. and Camera, M. and Corsini, A. and Tondo, C. and Rossini, A. and Pompilio, G.
EMBO Molecular Medicine 13 (9): e14365. 7 September 2021

Homology-directed repair protects the replicating genome from metabolic assaults.
Somyajit, K. and Spies, J. and Coscia, F. and Kirik, U. and Rask, M.B. and Lee, J.H. and Neelsen, K.J. and Mund, A. and Jensen, L.J. and Paull, T.T. and Mann, M. and Lukas, J.
Developmental Cell 56 (4): 461-477. 22 February 2021

Ultrahigh field MRI determination of water diffusion rates in ex vivo human lenses of different age.
Stahnke, T. and Lindner, T. and Guthoff, R. and Stachs, O. and Wree, A. and Langner, S. and Niendorf, T. and Grabow, N. and Glass, Ä. and Beller, E. and Polei, S.
Quantitative Imaging in Medicine and Surgery 11 (7): 3029-3041. July 2021

Data preparation protocol for low signal-to-noise ratio fluorine-19 MRI.
Starke, L. and Niendorf, T. and Waiczies, S.
Methods in Molecular Biology 2216 : 711-722. 2021

Denoising for improved parametric MRI of the kidney: protocol for nonlocal means filtering.
Starke, L. and Tabelow, K. and Niendorf, T. and Pohlmann, A.
Methods in Molecular Biology 2216 : 565-576. 2021

Hemophagocytic lymphohistiocytosis and thrombotic microangiopathy after parvovirus B19 infection and renal transplantation: a case report.
Steffen, C.J. and Koch, N. and Eckardt, K.U. and Amann, K. and Seelow, E. and Schreiber, A.
BMC Nephrology 22 (1): 337. 12 October 2021

Cardiomyocyte injury following acute ischemic stroke: protocol for a prospective observational cohort study.
Stengl, H. and Ganeshan, R. and Hellwig, S. and Blaszczyk, E. and Fiebach, J.B. and Nolte, C.H. and Bauer, A. and Schulz-Menger, J. and Endres, M. and Scheitz, J.F.
JMIR Research Protocols 10 (2): e24186. 5 February 2021

Cognitive impairment in multiple system atrophy is related to white matter damage detected by the T1-weighted/T2-weighted ratio.
Sugiyama, A. and Cooper, G. and Hirano, S. and Yokota, H. and Mori, M. and Shimizu, K. and Yakiyama, M. and Finke, C. and Brandt, A.U. and Paul, F. and Kuwabara, S.
European Neurology 84 (6): 435-443. November 2021

Magnetic resonance T1w/T2w ratio in the middle cerebellar peduncle might be a sensitive biomarker for multiple system atrophy.
Sugiyama, A. and Yokota, H. and Hirano, S. and Cooper, G. and Mukai, H. and Koide, K. and Wang, J. and Ito, S. and Finke, C. and Brandt, A.U. and Paul, F. and Kuwabara, S.
European Radiology 31 (6): 4277-4284. June 2021

Inhibiting lysine demethylase 1A improves L1CAM-specific CAR T cell therapy by unleashing antigen-independent killing via the FAS-FASL axis.
Sulejmani, O. and Grunewald, L. and Andersch, L. and Schwiebert, S. and Klaus, A. and Winkler, A. and Astrahantseff, K. and Eggert, A. and Henssen, A.G. and Schulte, J.H. and Anders, K. and Künkele, A.
Cancers 13 (21): 5489. 31 October 2021

Single-nuclei RNA-sequencing of plant tissues using a nanowell-based system.
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Serum creatinine and cystatin C-based estimates of glomerular filtration rate are misleading in acute heart failure.
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The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets.
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Nucleic Acids Research 49 (D): D605-D612. 8 January 2021

Neuroblastoma risk assessment and treatment stratification with hybrid capture-based panel sequencing.
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Journal of Personalized Medicine 11 (8): 691. August 2021

CALINCA - a novel pipeline for the identification of lncRNAs in podocyte disease.
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CD28 co-stimulus achieves superior CAR T cell effector function against solid tumors than 4-1BB co-stimulus.
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Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19.
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EMBO Molecular Medicine 13 (8): e14150. 9 August 2021

Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors.
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Clinical and virological characteristics of hospitalised COVID-19 patients in a German tertiary care centre during the first wave of the SARS-CoV-2 pandemic: a prospective observational study.
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Patient-specific modeling of diffuse large B-cell lymphoma.
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NAD(+) repletion reverses heart failure with preserved ejection fraction.
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Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states.
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Nature Immunology 22 (12): 1577-1589. December 2021

Aberrant phase separation of FUS leads to lysosome sequestering and acidification.
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Frontiers in Cell and Developmental Biology 9 : 716919. 22 October 2021

Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization.
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Science Advances 7 (31): eabh2791. July 2021

The discriminative ability of Prostate Health Index to detect prostate cancer is enhanced in combination with miR-222-3p.
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Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer.
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Tumor-associated microglia/macrophages as a predictor for survival in glioblastoma and temozolomide-induced changes in CXCR2 signaling with new resistance overcoming strategy by combination therapy.
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International Journal of Molecular Sciences 22 (20): 11180. 16 October 2021

A previously undescribed highly prevalent phage identified in a Danish Enteric Virome Catalog.
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mSystems 6 (5): e00382-21. 26 October 2021

Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics.
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Nature Communications 12 (1): 1366. 1 March 2021

A barcoded flow cytometric assay to explore the antibody responses against SARS-CoV-2 spike and its variants.
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Frontiers in Immunology 12 : 730766. September 2021

Endothelial cell orientation and polarity are controlled by shear stress and VEGF through distinct signaling pathways.
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Frontiers in Physiology 11 : 623769. 2 March 2021

Dual-view light-sheet imaging through a tilted glass interface using a deformable mirror.
Vladimirov, N. and Preusser, F. and Wisniewski, J. and Yaniv, Z. and Desai, R.A. and Woehler, A. and Preibisch, S.
Biomedical Optics Express 12 (4): 2186-2203. 1 April 2021

The traveling heads 2.0: multicenter reproducibility of quantitative imaging methods at 7 Tesla.
Voelker, M.N. and Kraff, O. and Goerke, S. and Laun, F.B. and Hanspach, J. and Pine, K.J. and Ehses, P. and Zaiss, M. and Liebert, A. and Straub, S. and Eckstein, K. and Robinson, S. and Nagel, A.N. and Stefanescu, M.R. and Wollrab, A. and Klix, S. and Felder, J. and Hock, M. and Bosch, D. and Weiskopf, N. and Speck, O. and Ladd, M.E. and Quick, H.H.
NeuroImage 232 : 117910. 15 May 2021

Circulating maternal sFLT1 (soluble fms-like tyrosine kinase-1) is sufficient to impair spiral arterial remodeling in a preeclampsia mouse model.
Vogtmann, R. and Heupel, J. and Herse, F. and Matin, M. and Hagmann, H. and Bendix, I. and Kräker, K. and Dechend, R. and Winterhager, E. and Kimmig, R. and Köninger, A. and Gellhaus, A.
Hypertension 78 (4): 1067-1079. September 2021

Biallelic mutations in L-dopachrome tautomerase (DCT) cause infantile nystagmus and oculocutaneous albinism.
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Human Genetics 140 (8): 1157-1168. August 2021

Cannabidiol converts NF(κ)B into a tumor suppressor in glioblastoma with defined antioxidative properties.
Volmar, M.N.M. and Cheng, J. and Alenezi, H. and Richter, S. and Haug, A. and Hassan, Z. and Goldberg, M. and Li, Y. and Hou, M. and Herold-Mende, C. and Maire, C.L. and Lamszus, K. and Flüh, C. and Held-Feindt, J. and Gargiulo, G. and Topping, G.J. and Schilling, F. and Saur, D. and Schneider, G. and Synowitz, M. and Schick, J.A. and Kälin, R.E. and Glass, R.
Neuro-Oncology 23 (11): 1898-1910. November 2021

Early response to first-line anti-PD-1 treatment in Hodgkin lymphoma: a PET-based analysis from the prospective, randomized phase II NIVAHL trial.
Voltin, C.A. and Mettler, J. and van Heek, L. and Goergen, H. and Müller, H. and Baues, C. and Keller, U. and Meissner, J. and Trautmann-Grill, K. and Kerkhoff, A. and Fuchs, M. and Sasse, S. and von Tresckow, B. and Dietlein, M. and Borchmann, P. and Engert, A. and Kobe, C. and Bröckelmann, P.J.
Clinical Cancer Research 27 (2): 402-407. January 2021

A biallelic variant in CLRN2 causes non-syndromic hearing loss in humans.
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Human Genetics 140 (6): 915-931. June 2021

Phylogeography and population differentiation in Hepatozoon canis (Apicomplexa: Hepatozoidae) reveal expansion and gene flow in world populations.
Vásquez-Aguilar, A.A. and Barbachano-Guerrero, A. and Angulo, D.F. and Jarquín-Díaz, V.H.
Parasites & Vectors 14 (1): 467. 14 September 2021

Familial thrombocytopenia due to a complex structural variant resulting in a WAC-ANKRD26 fusion transcript.
Wahlster, L. and Verboon, J.M. and Ludwig, L.S. and Black, S.C. and Luo, W. and Garg, K. and Voit, R.A. and Collins, R.L. and Garimella, K. and Costello, M. and Chao, K.R. and Goodrich, J.K. and DiTroia, S.P. and O’Donnell-Luria, A. and Talkowski, M.E. and Michelson, A.D. and Cantor, A.B. and Sankaran, V.G.
Journal of Experimental Medicine 218 (6): e20210444. 7 June 2021

Magnetic resonance imaging of multiple sclerosis at 7.0 Tesla.
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Journal of Visualized Experiments (168): e62142. 19 February 2021

Functional imaging using fluorine ((19)F) MR methods: basic concepts.
Waiczies, S. and Prinz, C. and Starke, L. and Millward, J.M. and Delgado, P.R. and Rosenberg, J. and Nazaré, M. and Waiczies, H. and Pohlmann, A. and Niendorf, T.
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Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection clusters based on integrated genomic surveillance, outbreak analysis and contact tracing in an urban setting.
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Clinical Infectious Diseases 74 (6): 1039-1046. 15 March 2021

Functional autoantibodies against G-protein coupled receptors in patients with persistent Long-COVID-19 symptoms.
Wallukat, G. and Hohberger, B. and Wenzel, K. and Fürst, J. and Schulze-Rothe, S. and Wallukat, A. and Hönicke, A.S. and Müller, J.
Journal of Translational Autoimmunity 4 : 100100. 16 April 2021

Single cell transcriptome sequencing on the Nanopore platform with ScNapBar.
Wang, Q. and Boenigk, S. and Boehm, V. and Gehring, N.H. and Altmueller, J. and Dieterich, C.
RNA 27 (7): 763-770. July 2021

TLR7 signaling drives the development of Sjögren's syndrome.
Wang, Y. and Roussel-Queval, A. and Chasson, L. and Hanna Kazazian, N. and Marcadet, L. and Nezos, A. and Sieweke, M.H. and Mavragani, C. and Alexopoulou, L.
Frontiers in Immunology 12 : 676010. 24 May 2021

Aging affects K(V)7 channels and perivascular adipose tissue-mediated vascular tone.
Wang, Y. and Yildiz, F. and Struve, A. and Kassmann, M. and Markó, L. and Köhler, M.B. and Luft, F.C. and Gollasch, M. and Tsvetkov, D.
Frontiers in Physiology 12 : 749709. 26 November 2021

Pericyte insulin receptors modulate retinal vascular remodeling and endothelial angiopoietin signaling.
Warmke, N. and Platt, F. and Bruns, A.F. and Ozber, C.H. and Haywood, N.J. and Abudushalamu, Y. and Slater, C. and Palin, V. and Sukumar, P. and Wheatcroft, S.B. and Yuldasheva, N.Y. and Kearney, M.T. and Griffin, K.J. and Cubbon, R.M.
Endocrinology 162 (11): bqab182. 1 November 2021

Swarm Learning for decentralized and confidential clinical machine learning.
Warnat-Herresthal, S. and Schultze, H. and Shastry, K.L. and Manamohan, S. and Mukherjee, S. and Garg, V. and Sarveswara, R. and Händler, K. and Pickkers, P. and Aziz, N.A. and Ktena, S. and Tran, F. and Bitzer, M. and Ossowski, S. and Casadei, N. and Herr, C. and Petersheim, D. and Behrends, U. and Kern, F. and Fehlmann, T. and Schommers, P. and Lehmann, C. and Augustin, M. and Rybniker, J. and Altmüller, J. and Mishra, N. and Bernardes, J.P. and Krämer, B. and Bonaguro, L. and Schulte-Schrepping, J. and De Domenico, E. and Siever, C. and Kraut, M. and Desai, M. and Monnet, B. and Saridaki, M. and Siegel, C.M. and Drews, A. and Nuesch-Germano, M. and Theis, H. and Heyckendorf, J. and Schreiber, S. and Kim-Hellmuth, S. and Nattermann, J. and Skowasch, D. and Kurth, I. and Keller, A. and Bals, R. and Nürnberg, P. and Rieß, O. and Rosenstiel, P. and Netea, M.G. and Theis, F. and Mukherjee, S. and Backes, M. and Aschenbrenner, A.C. and Ulas, T. and Breteler, M.M.B. and Giamarellos-Bourboulis, E.J. and Kox, M. and Becker, M. and Cheran, S. and Woodacre, M.S. and Goh, E.L. and Schultze, J.L.
Nature 594 (7862): 265-270. 10 June 2021

Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy.
Warnecke, N. and Ulmer, B.M. and Laufer, S.D. and Shibamiya, A. and Krämer, E. and Neuber, C. and Hanke, S. and Behrens, C. and Loos, M. and Münch, J. and Kühnisch, J. and Klaassen, S. and Eschenhagen, T. and Patten-Hamel, M. and Carrier, L. and Mearini, G.
Stem Cell Research 55 : 102489. August 2021

A homozygous AKNA frameshift variant is associated with microcephaly in a Pakistani family.
Waseem, S.S. and Moawia, A. and Budde, B. and Tariq, M. and Khan, A. and Ali, Z. and Khan, S. and Iqbal, M. and Malik, N.A. and Haque, S.U. and Altmüller, J. and Thiele, H. and Hussain, M.S. and Cirak, S. and Baig, S.M. and Nürnberg, P.
Genes 12 (10): 1494. October 2021

HunFlair: an easy-to-use tool for state-of-the-art biomedical named entity recognition.
Weber, L. and Sänger, M. and Münchmeyer, J. and Habibi, M. and Leser, U. and Akbik, A.
Bioinformatics 37 (17): 2792–2794. 1 September 2021

Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complex.
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Epigenetics & Chromatin 14 (1): 8. 19 January 2021

Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01.
Weiner, J. and Suwalski, P. and Holtgrewe, M. and Rakitko, A. and Thibeault, C. and Müller, M. and Patriki, D. and Quedenau, C. and Krüger, U. and Ilinsky, V. and Popov, I. and Balnis, J. and Jaitovich, A. and Helbig, E.T. and Lippert, L.J. and Stubbemann, P. and Real, L.M. and Macías, J. and Pineda, J.A. and Fernandez-Fuertes, M. and Wang, X. and Karadeniz, Z. and Saccomanno, J. and Doehn, J.M. and Hübner, R.H. and Hinzmann, B. and Salvo, M. and Blueher, A. and Siemann, S. and Jurisic, S. and Beer, J.H. and Rutishauser, J. and Wiggli, B. and Schmid, H. and Danninger, K. and Binder, R. and Corman, V.M. and Mühlemann, B. and Arjun Arkal, R. and Fragiadakis, G.K. and Mick, E. and Calfee, C.S. and Erle, D.J. and Hendrickson, C.M. and Kangelaris, K.N. and Krummel, M.F. and Woodruff, P.G. and Langelier, C.R. and Venkataramani, U. and García, F. and Zyla, J. and Drosten, C. and Braun, A. and Jones, T.C. and Suttorp, N. and Witzenrath, M. and Hippenstiel, S. and Zemojtel, T. and Skurk, C. and Wolfgang, P. and Borodina, T. and Ripke, S. and Sander, L.E. and Beule, D. and Landmesser, U. and Guettouche, T. and Kurth, F. and Heidecker, B.
EClinicalMedicine 40 : 101099. October 2021

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis.
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Cell 184 (26): 6243-6261. 22 December 2021

De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis.
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American Journal of Human Genetics 108 (2): 357-367. 4 February 2021

Myeloid transformation by MLL-ENL depends strictly on C/EBP.
Wesolowski, R. and Kowenz-Leutz, E. and Zimmermann, K. and Dörr, D. and Hofstätter, M. and Slany, R.K. and Mildner, A. and Leutz, A.
Life Science Alliance 4 (1): e202000709. January 2021

Impact of sequence type and field strength (1.5, 3, and 7T) on 4D flow MRI hemodynamic aortic parameters in healthy volunteers.
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Magnetic Resonance in Medicine 85 (2): 721-733. February 2021

Aestivation motifs explain hypertension and muscle mass loss in mice with psoriatic skin barrier defect.
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Acta Physiologica 232 (1): e13628. May 2021

The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells.
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Molecular Metabolism 45 : 101151. March 2021

In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo.
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eLife 10 : e62019. 20 April 2021

The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms.
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JCI Insight 6 (2): 136083. 25 January 2021

Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
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Nature 597 (7874): 87-91. 2 September 2021

Cell-type specialization is encoded by specific chromatin topologies.
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Nature 599 (7886): 684-691. 25 November 2021

Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine learning toolbox.
Wirbel, J. and Zych, K. and Essex, M. and Karcher, N. and Kartal, E. and Salazar, G. and Bork, P. and Sunagawa, S. and Zeller, G.
Genome Biology 22 (1): 93. 30 March 2021

A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion.
Witte, F. and Ruiz-Orera, J. and Ciolli Mattioli, C. and Blachut, S. and Adami, E. and Schulz, J.F. and Schneider-Lunitz, V. and Hummel, O. and Patone, G. and Mücke, M.B. and Šilhavý, Jan and Heinig, M. and Bottolo, L. and Sanchis, D. and Vingron, M. and Chekulaeva, M. and Pravenec, M. and Hubner, N. and van Heesch, S.
Genome Biology 22 (1): 191. 28 June 2021

The mTOR inhibitor temsirolimus added to rituximab combined with dexamethasone, cytarabine, and cisplatinum (R-DHAP) for the treatment of patients with relapsed or refractory DLBCL - results from the phase-II STORM trial.
Witzens-Harig, M. and Viardot, A. and Keller, U. and Wosniok, J. and Deuster, O. and Klemmer, J. and Geueke, A.M. and Meißner, J. and Ho, A.D. and Atta, J. and Marks, R. and La Rosée, P. and Buske, C. and Dreyling, M.H. and Hess, G.
HemaSphere 5 (10): e636. October 2021

Ythdf is a N6-methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila.
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EMBO Journal 40 (4): e104975. 15 February 2021

Bioprinted cancer model of neuroblastoma in a renal microenvironment as an efficiently applicable drug testing platform.
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International Journal of Molecular Sciences 23 (1): 122. 23 December 2021

Wnt signalling pathway in bladder cancer.
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Cellular Signalling 79 : 109886. March 2021

Identification of unique long non-coding RNAs as putative biomarkers for chromophobe renal cell carcinoma.
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Personalized Medicine 18 (1): 9-19. January 2021

Alemtuzumab plus CHOP versus CHOP in elderly patients with peripheral T-cell lymphoma: the DSHNHL2006-1B/ACT-2 trial.
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Leukemia 35 (1): 143-155. January 2021

Patient-derived xenografts from solid tumors (PDX) for models of metastasis.
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Methods in Molecular Biology 2294 : 43-58. 2021

Aberrant expression of and cell death induction by engagement of the MHC-II chaperone CD74 in anaplastic large cell lymphoma (ALCL).
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Cancers 13 (19): 5012. 1 October 2021

Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology.
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International Journal of Hyperthermia 38 (1): 715-731. 28 April 2021

Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
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iScience 24 (3): 102151. 19 March 2021

Efficacy and safety of renal denervation for hypertension in patients with chronic kidney disease: a meta-analysis.
Xia, M. and Liu, T. and Chen, D. and Huang, Y.
International Journal of Hyperthermia 38 (1): 732-742. 2021

An immune-related lncRNA signature to predict survival in glioma patients.
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Cellular and Molecular Neurobiology 41 (2): 365-375. March 2021

Histamine triggers microglial responses indirectly via astrocytes and purinergic signaling.
Xia, P. and Logiacco, F. and Huang, Y. and Kettenmann, H. and Semtner, M.
Glia 69 (9): 2291-2304. September 2021

CRNKL1 is a highly selective regulator of intron-retaining HIV-1 and cellular mRNAs.
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mBio 12 (1): e02525-20. 19 January 2021

Activation of autophagic flux blunts cardiac ischemia/reperfusion injury.
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Circulation Research 129 (3): 435-450. 23 July 2021

Systematic analysis of binding of transcription factors to noncoding variants.
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Nature 591 (7848): 147-151. March 2021

ME2 promotes proneural–mesenchymal transition and lipogenesis in glioblastoma.
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Frontiers in Oncology 11 : 715593. 23 July 2021

Depletion of aneuploid cells in human embryos and gastruloids.
Yang, M. and Rito, T. and Metzger, J. and Naftaly, J. and Soman, R. and Hu, J. and Albertini, D.F. and Barad, D.H. and Brivanlou, A.H. and Gleicher, N.
Nature Cell Biology 23 (4): 314-321. April 2021

(Pro)renin receptor inhibition reduces plasma cholesterol and triglycerides but does not attenuate atherosclerosis in atherosclerotic mice.
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Frontiers in Cardiovascular Medicine 8 : 725203. 24 December 2021

Shared and oppositely regulated transcriptomic signatures in Huntington's disease and brain ischemia confirm known and unveil novel potential neuroprotective genes.
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Neurobiology of Aging 104 : 122.e1-122.e17. August 2021

The worm-specific immune response in multiple sclerosis patients receiving controlled Trichuris suis ova immunotherapy.
Yordanova, I.A. and Ebner, F. and Schulz, A.R. and Steinfelder, S. and Rosche, B. and Bolze, A. and Paul, F. and Mei, H.E. and Hartmann, S.
Life 11 (2): 101. 29 January 2021

Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging.
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Cell Stem Cell 28 (8): 1473-1482. 5 August 2021

Active perception during angiogenesis: filopodia speed up Notch selection of tip cells in silico and in vivo.
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Philosophical Transactions of the Royal Society of London Series B Biological Sciences 376 (1821): 20190753. 29 March 2021

Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting.
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Journal of Cachexia Sarcopenia and Muscle 13 (1): 713-727. February 2021

Frailty and falls in people living with multiple sclerosis.
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Archives of Physical Medicine and Rehabilitation 103 (5): 952-957. 24 November 2021

Remodeling of an in vitro microvessel exposed to cyclic mechanical stretch.
Zeinali, S. and Thompson, E.K. and Gerhardt, H. and Geiser, T. and Guenat, O.T.
APL Bioengineering 5 (2): 026102. June 2021

Quality assurance of quantitative cardiac T1-mapping in multicenter clinical trials - a T1 phantom program from the hypertrophic cardiomyopathy registry (HCMR) study.
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International Journal of Cardiology 330 : 251-258. 1 May 2021

RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis.
Zhang, S. and Übelmesser, N. and Josipovic, N. and Forte, G. and Slotman, J.A. and Chiang, M. and Gothe, H.J. and Gusmao, E.G. and Becker, C. and Altmüller, J. and Houtsmuller, A.B. and Roukos, V. and Wendt, K.S. and Marenduzzo, D. and Papantonis, A.
Science Advances 7 (43): eabg8205. 22 October 2021

Asymmetric opening of the homopentameric 5-HT(3A) serotonin receptor in lipid bilayers.
Zhang, Y. and Dijkman, P.M. and Zou, R. and Zandl-Lang, M. and Sanchez, R.M. and Eckhardt-Strelau, L. and Köfeler, H. and Vogel, H. and Yuan, S. and Kudryashev, M.
Nature Communications 12 (1): 1074. 16 February 2021

Oscillations of Delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells.
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Nature Communications 12 (1): 1318. 26 February 2021

A simple pressure-assisted method for MicroED specimen preparation.
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Nature Communications 12 (1): 5036. 19 August 2021

Physiological system analysis of the kidney by high-temporal-resolution T(2)* monitoring of an oxygenation step response.
Zhao, K. and Pohlmann, A. and Feng, Q. and Mei, Y. and Yang, G. and Yi, P. and Feng, Q. and Chen, W. and Zhou, L. and Wu, E.X. and Seeliger, E. and Niendorf, T. and Feng, Y.
Magnetic Resonance in Medicine 85 (1): 334-345. January 2021

Age impairs soluble guanylyl cyclase function in mouse mesenteric arteries.
Zhong, C. and Xu, M. and Boral, S. and Summer, H. and Lichtenberger, F.B. and Erdoğan, C. and Gollasch, M. and Golz, S. and Persson, P.B. and Schleifenbaum, J. and Patzak, A. and Khedkar, P.H.
International Journal of Molecular Sciences 22 (21): 11412. 22 October 2021

Association between erythrocyte dynamics and vessel remodelling in developmental vascular networks.
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Journal of the Royal Society Interface 18 (179): 20210113. June 2021

Generation of human iPSC-derived neural progenitor cells (NPCs) as drug discovery model for neurological and mitochondrial disorders.
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Bio-protocol 11 (5): e3939. 5 March 2021

Somatostatin interneurons activated by 5-HT(2A) receptor suppress slow oscillations in medial entorhinal cortex.
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eLife 10 : e66960. 31 March 2021

SPLICE-q: a Python tool for genome-wide quantification of splicing efficiency.
de Melo Costa, V.R. and Pfeuffer, J. and Louloupi, A. and Ørom, U.A.V. and Piro, R.M.
BMC Bioinformatics 22 (1): 368. 15 July 2021

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
de Rojas, I. and Moreno-Grau, S. and Tesi, N. and Grenier-Boley, B. and Andrade, V. and Jansen, I.E. and Pedersen, N.L. and Stringa, N. and Zettergren, A. and Hernández, I. and Montrreal, L. and Antúnez, C. and Antonell, A. and Tankard, R.M. and Bis, J.C. and Sims, R. and Bellenguez, C. and Quintela, I. and González-Perez, A. and Calero, M. and Franco-Macías, E. and Macías, J. and Blesa, R. and Cervera-Carles, L. and Menéndez-González, M. and Frank-García, A. and Royo, J.L. and Moreno, F. and Huerto Vilas, R. and Baquero, M. and Diez-Fairen, M. and Lage, C. and García-Madrona, S. and García-González, P. and Alarcón-Martín, E. and Valero, S. and Sotolongo-Grau, O. and Ullgren, A. and Naj, A.C. and Lemstra, A.W. and Benaque, A. and Pérez-Cordón, A. and Benussi, A. and Rábano, A. and Padovani, A. and Squassina, A. and de Mendonça, A. and Arias Pastor, A. and Kok, A.A.L. and Meggy, A. and Pastor, A.B. and Espinosa, A. and Corma-Gómez, A. and Martín Montes, A. and Sanabria, Á. and 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Selbæk, G. and Ortega, G. and Chêne, G. and Hadjigeorgiou, G. and Rossi, G. and Spalletta, G. and Giaccone, G. and Grande, G. and Binetti, G. and Papenberg, G. and Hampel, H. and Bailly, H. and Zetterberg, H. and Soininen, H. and Karlsson, I.K. and Alvarez, I. and Appollonio, I. and Giegling, I. and Skoog, I. and Saltvedt, I. and Rainero, I. and Rosas Allende, I. and Hort, J. and Diehl-Schmid, J. and Van Dongen, J. and Vidal, J.S. and Lehtisalo, J. and Wiltfang, J. and Thomassen, J.Q. and Kornhuber, J. and Haines, J.L. and Vogelgsang, J. and Pineda, J.A. and Fortea, J. and Popp, J. and Deckert, J. and Buerger, K. and Morgan, K. and Fließbach, K. and Sleegers, K. and Molina-Porcel, L. and Kilander, L. and Weinhold, L. and Farrer, L.A. and Wang, L.S. and Kleineidam, L. and Farotti, L. and Parnetti, L. and Tremolizzo, L. and Hausner, L. and Benussi, L. and Froelich, L. and Ikram, M.A. and Deniz-Naranjo, M.C. and Tsolaki, M. and Rosende-Roca, M. and Löwenmark, M. and Hulsman, M. and Spallazzi, M. and Pericak-Vance, M.A. and Esiri, M. and Bernal Sánchez-Arjona, M. and Dalmasso, M.C. and Martínez-Larrad, M.T. and Arcaro, M. and Nöthen, M.M. and Fernández-Fuertes, M. and Dichgans, M. and Ingelsson, M. and Herrmann, M.J. and Scherer, M. and Vyhnalek, M. and Kosmidis, M.H. and Yannakoulia, M. and Schmid, M. and Ewers, M. and Heneka, M.T. and Wagner, M. and Scamosci, M. and Kivipelto, M. and Hiltunen, M. and Zulaica, M. and Alegret, M. and Fornage, M. and Roberto, N. and van Schoor, N.M. and Seidu, N.M. and Banaj, N. and Armstrong, N.J. and Scarmeas, N. and Scherbaum, N. and Goldhardt, O. and Hanon, O. and Peters, O. and Skrobot, O.A. and Quenez, O. and Lerch, O. and Bossù, P. and Caffarra, P. and Dionigi Rossi, P. and Sakka, P. and Mecocci, P. and Hoffmann, P. and Holmans, P.A. and Fischer, P. and Riederer, P. and Yang, Q. and Marshall, R. and Kalaria, R.N. and Mayeux, R. and Vandenberghe, R. and Cecchetti, R. and Ghidoni, R. and Frikke-Schmidt, R. and Sorbi, S. and Hägg, S. and Engelborghs, S. and Helisalmi, S. and Botne Sando, S. and Kern, S. and Archetti, S. and Boschi, S. and Fostinelli, S. and Gil, S. and Mendoza, S. and Mead, S. and Ciccone, S. and Djurovic, S. and Heilmann-Heimbach, S. and Riedel-Heller, S. and Kuulasmaa, T. and Del Ser, T. and Lebouvier, T. and Polak, T. and Ngandu, T. and Grimmer, T. and Bessi, V. and Escott-Price, V. and Giedraitis, V. and Deramecourt, Vi. and Maier, W. and Jian, X. and Pijnenburg, Y.A.L. and Kehoe, P.G. and Garcia-Ribas, G. and Sánchez-Juan, P. and Pastor, P. and Pérez-Tur, J. and Piñol-Ripoll, G. and Lopez de Munain, A. and García-Alberca, J.M. and Bullido, M.J. and Álvarez, V. and Lleó, A. and Real, L.M. and Mir, P. and Medina, M. and Scheltens, P. and Holstege, H. and Marquié, M. and Sáez, M.E. and Carracedo, Á. and Amouyel, P. and Schellenberg, G.D. and Williams, J. and Seshadri, S. and van Duijn, C.M. and Mather, K.A. and Sánchez-Valle, R. and Serrano-Ríos, M. and Orellana, A. and Tárraga, L. and Blennow, K. and Huisman, M. and Andreassen, O.A. and Posthuma, D. and Clarimón, J. and Boada, M. and van der Flier, W.M. and Ramirez, A. and Lambert, J.C. and van der Lee, S.J. and Ruiz, A.
Nature Communications 12 (1): 3417. 7 June 2021

Camera-based objective measures of Parkinson's disease gait features.
van Kersbergen, J. and Otte, K. and de Vries, N.M. and Bloem, B.R. and Röhling, H.M. and Mansow-Model, S. and van der Kolk, N.M. and Overeem, S. and Zinger, S. and van Gilst, M.M.
BMC Research Notes 14 (1): 329. 26 August 2021

In vivo renin activity imaging in the kidney of progeroid Ercc1 mutant mice.
van Thiel, B.S. and van der Linden, J. and Ridwan, Y. and Garrelds, I.M. and Vermeij, M. and Clahsen-van Groningen, M.C. and Qadri, F. and Alenina, N. and Bader, M. and Roks, A.J.M. and Danser, A.H.J. and Essers, J. and van der Pluijm, I.
International Journal of Molecular Sciences 22 (22): 12433. 18 November 2021

High-affinity T-cell receptor specific for MyD88 L265P mutation for adoptive T-cell therapy of B-cell malignancies.
Çınar, Ö. and Brzezicha, B. and Grunert, C. and Kloetzel, P.M. and Beier, C. and Peuker, C.A. and Keller, U. and Pezzutto, A. and Busse, A.
Journal for ImmunoTherapy of Cancer 9 (7): e002410. 30 July 2021

Book Section

Renin-angiotensin-aldosterone system.
Bader, M.
In: Encyclopedia of Molecular Pharmacology : Third Edition. Springer, Cham, 1353-1358. ISBN 978-3-030-57400-0 2021

Natural compounds and synthetic drugs to target type-2 cannabinoid (CB(2)) receptor.
Guba, W. and Nazaré, M. and Grether, U.
In: New tools to interrogate endocannabinoid signalling : from natural compounds to synthetic drugs. RSC Drug Discovery Series, 76 . Royal Society of Chemistry, Croydon, 89-167. ISBN 978-1-78801-801-2 2021

Glial cells: neuroglia.
Kettenmann, H. and Verkhratsky, A.
In: Neuroscience in the 21st century : from basic to clinical. Springer, New York, NY, 1-36. ISBN 978-1-4614-6434-1 12 April 2021

Gene expression analysis and next-generation sequencing.
Lindberg, E.L. and Hübner, N.
In: Encyclopedia of Molecular Pharmacology : Third Edition. Springer, Cham, 684-688. ISBN 978-3-030-57400-0 2021

Bradykinin receptors.
Maghsodi, S. and Qadri, F. and Bader, M.
In: Reference Module in Life Sciences. Encyclopedia of Biological Chemistry III (Third Edition), 6 . Elsevier, 142-160. ISBN 978-0-12-822040-5 2021

Genomic landscape and clonal evolution of AML.
Noerenberg, D. and Damm, F. and Bullinger, L.
In: Acute Myeloid Leukemia. Hematologic Malignancies . Springer, Cham, 103-118. ISBN 978-3-030-72675-1 2021

Hypertensive disorders in pregnancy and eclampsia.
Staff, A.C. and Dechend, R.
In: The EBCOG postgraduate textbook of obstetrics & gynaecology : obstetrics & maternal-fetal medicine. Cambridge Medicine . Cambridge University Press, Cambridge, 201-212. ISBN 9781108863049 2021

Cl(-) channels and Cl(-)/H(+) exchangers.
Ullrich, F. and Jentsch, T.J.
In: Encyclopedia of Molecular Pharmacology : Third Edition. Springer, Cham, 470-477. ISBN 978-3-030-57400-0 2021

A-kinase anchoring proteins (AKAPs).
Walker-Gray, R. and Klussmann, E.
In: Encyclopedia of Molecular Pharmacology : Third Edition. Springer, Cham, 78-83. ISBN 978-3-030-57400-0 2021

Conference or Workshop Item

Microscopy with undetected photons in the mid-infrared.
Kviatkovsky, I. and Chrzanowski, H.M. and Avery, E.G. and Bartolomaeus, H. and Ramelow, S.
In: Conference on Lasers and Electro-Optics 2021, 9-14 May 2021, San Jose, CA, USA. May 2021

KDD Health Day/DSHealth 2021: Joint KDD 2021 Health Day and 2021 KDD Workshop on Applied Data Science for Healthcare: state of XAI and trustworthiness in health.
Wang, F. and Chakraborty, P. and Xu, T. and Hsueh, P.Y.S. and Sun, X. and Stiglic, G. and Crane, G. and Bian, J. and Haghverdi, L. and Yao, L. and Buettner, F.
In: KDD '21: The 27th ACM SIGKDD Conference on Knowledge Discovery and Data Mining, 14-18 Aug 2021, Virtual Event Singapore. 14 August 2021

Extend, don’t rebuild: Phrasing conditional graph modification as autoregressive sequence labelling.
Weber, L. and Münchmeyer, J. and Garda, S. and Leser, U.
In: 2021 Conference on Empirical Methods in Natural Language Processing, EMNLP 2021, 7-11 Nov 2021, Punta Cana, Dominican Republic. November 2021


Metastasis : methods and protocols.
Stein, U.S., ed.
Methods in Molecular Biology, 2294 . Springer / Humana Press, New York, NY. ISBN 978-1-0716-1349-8 2021

Preclinical MRI of the kidney : methods and protocols.
Pohlmann, A. and Niendorf, T., eds.
Methods in Molecular Biology, 2216 . Springer / Humana Press, New York, NY. ISBN 978-1-0716-0977-4 2021


TSLP as druggable target - a silver-lining for atopic diseases?
Adhikary, P.P. and Tan, Z. and Page, B.D.G. and Hedtrich, S.
Pharmacology & Therapeutics 217 : 107648. January 2021

Gene delivery to the skin - how far have we come?
Ain, Q.U. and Campos, E.V.R. and Huynh, A. and Witzigmann, D. and Hedtrich, S.
Trends in Biotechnology 39 (5): 474-487. May 2021

Autophagy in healthy aging and disease.
Aman, Y. and Schmauck-Medina, T. and Hansen, M. and Morimoto, R.I. and Simon, A.K. and Bjedov, I. and Palikaras, K. and Simonsen, A. and Johansen, T. and Tavernarakis, N. and Rubinsztein, D.C. and Partridge, L. and Kroemer, G. and Labbadia, J. and Fang, E.F.
Nature Aging 1 (8): 634-650. 12 August 2021

The gut microbiome in hypertension: recent advances and future perspectives.
Avery, E.G. and Bartolomaeus, H. and Maifeld, A. and Marko, L. and Wiig, H. and Wilck, N. and Rosshart, S.P. and Forslund, S.K. and Muller, D.N.
Circulation Research 128 (7): 934-950. 2 April 2021

Assessing the (anti)-inflammatory potential of diets.
Bahr, L.S. and Franz, K. and Mähler, A.
Current Opinion in Clinical Nutrition and Metabolic Care 24 (5): 402-410. 1 September 2021

Vasopressin-vermittelte Wasserrückresorption im Sammelrohr der Niere [Vasopressin-mediated water reabsorption in the renal collecting duct].
Baltzer, S. and Klussmann, E.
BIOspektrum 27 (2): 165-167. March 2021

Clinical and neuroimaging findings in MOGAD - MRI and OCT.
Bartels, F. and Lu, A. and Oertel, F.C. and Finke, C. and Paul, F. and Chien, C.
Clinical and Experimental Immunology 206 (3): 266-281. December 2021

Viewpoints on the first transatlantic GPCR symposium for early-career investigators.
Bender, B.J. and Bock, A. and Nesheva, D.N. and Perry-Hauser, N.A.
ACS Pharmacology & Translational Science 4 (5): 1705-1711. 8 October 2021

SARS-CoV-2 in humans.
Binder, M. and Wyler, E.
Berliner und Munchener Tierarztliche Wochenschrift 134 : 1-13. 30 April 2021

Role of CMR imaging in diagnostics and evaluation of cardiac involvement in muscle dystrophies.
Blaszczyk, E. and Gröschel, J. and Schulz-Menger, J.
Current Heart Failure Reports 18 (4): 211-224. August 2021

Allosteric coupling and biased agonism in G protein-coupled receptors.
Bock, A. and Bermudez, M.
FEBS Journal 288 (8): 2513-2528. April 2021

Implications of SGLT inhibition on redox signalling in atrial fibrillation.
Bode, D. and Semmler, L. and Oeing, C.U. and Alogna, A. and Schiattarella, G.G. and Pieske, B.M. and Heinzel, F.R. and Hohendanner, F.
International Journal of Molecular Sciences 22 (11): 5937. 31 May 2021

A comparison of metabolic labeling and statistical methods to infer genome-wide dynamics of RNA turnover.
Boileau, E. and Altmüller, J. and Naarmann-de Vries, I.S. and Dieterich, C.
Briefings in Bioinformatics 22 (6): bbab219. November 2021

Methodology of measuring postoperative cognitive dysfunction: a systematic review.
Borchers, F. and Spies, C.D. and Feinkohl, I. and Brockhaus, W.R. and Kraft, A. and Kozma, P. and Fislage, M. and Kühn, S. and Ionescu, C. and Speidel, S. and Hadzidiakos, D. and Veldhuijzen, D.S. and Yürek, F. and Evered, L.A. and Ottens, T.H.
British Journal of Anaesthesia 126 (6): 1119-1127. June 2021

The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons.
Borroto-Escuela, D.O. and Ferraro, L. and Beggiato, S. and Narváez, M. and Fores-Pons, R. and Alvarez-Contino, J.E. and Wydra, K. and Frankowska, M. and Bader, M. and Filip, M. and Fuxe, K.
Pharmacological Reports 73 (4): 1096-1108. August 2021

Myogenic cell transplantation in genetic and acquired diseases of skeletal muscle.
Boyer, O. and Butler-Browne, G. and Chinoy, H. and Cossu, G. and Galli, F. and Lilleker, J.B. and Magli, A. and Mouly, V. and Perlingeiro, R.R. and Previtali, S.C. and Sampaolesi, M. and Smeets, H. and Schoewel-Wolf, V. and Spuler, S. and Torrente, Y. and Van Tienen, F.
Frontiers in Genetics 12 : 702547. August 2021

Cannabinoid receptor type 2 ligands: an analysis of granted patents since 2010.
Brennecke, B. and Gazzi, T. and Atz, K. and Fingerle, J. and Kuner, P. and Schindler, T. and de Weck, G. and Nazaré, M. and Grether, U.
Pharmaceutical Patent Analyst 10 (3): 111-163. May 2021

Non-coding RNAs: lncRNAs, miRNAs, and piRNAs in sexual development.
Burgos, M. and Hurtado, A. and Jiménez, R. and Barrionuevo, F.J.
Sexual Development 15 (5-6): 335-350. December 2021

Atypical antipsychotics and metabolic syndrome: from molecular mechanisms to clinical differences.
Carli, M. and Kolachalam, S. and Longoni, B. and Pintaudi, A. and Baldini, M. and Aringhieri, S. and Fasciani, I. and Annibale, P. and Maggio, R. and Scarselli, M.
Pharmaceuticals 14 (3): 238. March 2021

Neuromodulation and behavioral flexibility in larval zebrafish: from neurotransmitters to circuits.
Corradi, L. and Filosa, A.
Frontiers in Molecular Neuroscience 14 : 718951. 15 July 2021

Cardiac sarcomere mechanics in health and disease.
Crocini, C. and Gotthardt, M.
Biophysical Reviews 13 (5): 637-652. October 2021

Personalisierte Medizin in der Kinderonkologie: Wo stehen wir heute?
Deubzer, H.E. and Schulte, J.H. and Eggert, A.
Pädiatrie up2date 16 (4): 325-342. December 2021

Current applications and future development of magnetic resonance fingerprinting in diagnosis, characterization, and response monitoring in cancer.
Ding, H. and Velasco, C. and Ye, H. and Lindner, T. and Grech-Sollars, M. and O’Callaghan, J. and Hiley, C. and Chouhan, M.D. and Niendorf, T. and Koh, D.M. and Prieto, C. and Adeleke, S.
Cancers 13 (19): 4742. 1 October 2021

Sensory neurons: the formation of T-shaped branches is dependent on a cGMP-dependent signaling cascade.
Dumoulin, A. and Schmidt, H. and Rathjen, F.G.
Neuroscientist 27 (1): 47-57. 1 February 2021

The EHA Research Roadmap: Malignant Myeloid Diseases.
Döhner, H. and Malcovati, L. and Ossenkoppele, G.J. and Hochhaus, A. and Maria Vannucchi, A. and Bullinger, L. and Cervantes, F. and Craddock, C. and de Witte, T. and Döhner, K. and Dombret, H. and Fenaux, P. and Geissler, J. and Germing, U. and Guilhot, F. and Harrison, C. and Hellström-Lindberg, E. and Passamonti, F. and Sierra, J. and Skoda, R. and Wierzbowska, A.
HemaSphere 5 (9): e635. September 2021

Thymoquinone: a tie-breaker in SARS-CoV2-infected cancer patients?
Elgohary, S. and Elkhodiry, A.A. and Amin, N.S. and Stein, U. and El Tayebi, H.M.
Cells 10 (2): 302. 2 February 2021

Polymer models are a versatile tool to study chromatin 3D organization.
Esposito, A. and Bianco, S. and Fiorillo, L. and Conte, M. and Abraham, A. and Musella, F. and Nicodemi, M. and Prisco, A. and Chiariello, A.M.
Biochemical Society Transactions 49 (4): 1675-1684. August 2021

Humane neuromuskuläre Organoide - Anwendung und Perspektive [Human neuromuscular organoids - Application and perspective].
Faustino Martins, J.M. and Nguyen, L.V.N. and Gouti, M.
BIOspektrum 27 (2): 135-138. March 2021

The role of high-resolution analytical techniques in the development of functional foods.
Fernández-Ochoa, Á. and Leyva-Jiménez, F.J. and De la Luz Cádiz-Gurrea, M. and Pimentel-Moral, S. and Segura-Carretero, A.
International Journal of Molecular Sciences 22 (6): 3220. 22 March 2021

The role of mitochondrial dynamics in cardiovascular diseases.
Forte, M. and Schirone, L. and Ameri, P. and Basso, C. and Catalucci, D. and Modica, J. and Chimenti, C. and Crotti, L. and Frati, G. and Rubattu, S. and Schiattarella, G.G. and Torella, D. and Perrino, C. and Indolfi, C. and Sciarretta, S.
British Journal of Pharmacology 178 (10): 2060-2076. May 2021

Astrocyte-derived Wnt growth factors are required for endothelial blood-brain barrier maintenance.
Guérit, S. and Fidan, E. and Macas, J. and Czupalla, C.J. and Figueiredo, R. and Vijikumar, A. and Yalcin, B.H. and Thom, S. and Winter, P. and Gerhardt, H. and Devraj, K. and Liebner, S.
Progress in Neurobiology 199 : 101937. April 2021

Out of control: the role of the ubiquitin proteasome system in skeletal muscle during inflammation.
Haberecht-Müller, S. and Krüger, E. and Fielitz, J.
Biomolecules 11 (9): 1327. September 2021

The dynamics of chromatin architecture in brain development and function.
Harabula, I. and Pombo, A.
Current Opinion in Genetics & Development 67 : 84-93. April 2021

COVID-19 und akute Nierenschädigung im Intensivbereich [COVID-19 and acute kidney injury in the intensive care unit].
Hardenberg, J.H.B. and Stockmann, H. and Eckardt, K.U. and Schmidt-Ott, K.M.
Nephrologe 16 (1): 20-25. January 2021

Cold-shock domains - abundance, structure, properties, and nucleic-acid binding.
Heinemann, U. and Roske, Y.
Cancers 13 (2): 190. 7 January 2021

Mit Einzelzell-Genomik die Entscheidungen von Zellen verfolgen [Deciphering cell fate decisions using single cell genomics].
Hu, B. and Junker, J.P.
BIOspektrum 27 (1): 25-27. February 2021

What is a β cell? - Chapter I in the Human Islet Research Network (HIRN) review series.
Kaestner, K.H. and Campbell-Thompson, M. and Dor, Y. and Gill, R.G. and Glaser, B. and Kim, S.K. and Sander, M. and Stabler, C. and Stewart, A.F. and Powers, A.C.
Molecular Metabolism 53 : 101323. November 2021

CRISPR-based diagnostics.
Kaminski, M.M. and Abudayyeh, O.O. and Gootenberg, J.S. and Zhang, F. and Collins, J.J.
Nature Biomedical Engineering 5 (7): 643-656. July 2021

Hypoxia-inducible factors not only regulate but also are myeloid-cell treatment targets.
Kling, L. and Schreiber, A. and Eckardt, K.U. and Kettritz, R.
Journal of Leukocyte Biology 110 : 61-75. July 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Klionsky, D.J. and Abdel-Aziz, A.K. and Abdelfatah, S. and Abdellatif, M. and Abdoli, A. and Abel, S. and Abeliovich, H. and Abildgaard, M.H. and Abudu, Y.P. and Acevedo-Arozena, A. and Adamopoulos, I.E. and Adeli, K. and Adolph, T.E. and Adornetto, A. and Aflaki, E. and Agam, G. and Agarwal, A. and Aggarwal, B.B. and Agnello, M. and Agostinis, P. and Agrewala, J.N. and Agrotis, A. and Aguilar, P.V. and Ahmad, S.T. and Ahmed, Z.M. and Ahumada-Castro, U. and Aits, S. and Aizawa, S. and Akkoc, Y. and Akoumianaki, T. and Akpinar, H.A. and Al-Abd, A.M. and Al-Akra, L. and Al-Gharaibeh, A. and Alaoui-Jamali, M.A. and Alberti, S. and Alcocer-Gómez, E. and Alessandri, C. and Ali, M. and Alim Al-Bari, M.A. and Aliwaini, S. and Alizadeh, J. and Almacellas, E. and Almasan, A. and Alonso, A. and Alonso, G.D. and Altan-Bonnet, N. and Altieri, D.C. and Álvarez, E.M.C. and Alves, S. and Alves da Costa, C. and Alzaharna, M.M. and Amadio, M. and Amantini, C. and Amaral, C. and Ambrosio, S. and Amer, A.O. and Ammanathan, V. and An, Z. and Andersen, S.U. and Andrabi, S.A. and Andrade-Silva, M. and Andres, A.M. and Angelini, S. and Ann, D. and Anozie, U.C. and Ansari, M.Y. and Antas, P. and Antebi, A. and Antón, Z. and Anwar, T. and Apetoh, L. and Apostolova, N. and Araki, T. and Araki, Y. and Arasaki, K. and Araújo, W.L. and Araya, J. and Arden, C. and Arévalo, M.A. and Arguelles, S. and Arias, E. and Arikkath, J. and Arimoto, H. and Ariosa, A.R. and Armstrong-James, D. and Arnauné-Pelloquin, L. and Aroca, A. and Arroyo, D.S. and Arsov, I. and Artero, R. and Asaro, D.M.L. and Aschner, M. and Ashrafizadeh, M. and Ashur-Fabian, O. and Atanasov, A.G. and Au, A.K. and Auberger, P. and Auner, H.W. and Aurelian, L. and Autelli, R. and Avagliano, L. and Ávalos, Y. and Aveic, S. and Aveleira, C.A. and Avin-Wittenberg, T. and Aydin, Y. and Ayton, S. and Ayyadevara, S. and Azzopardi, M. and Baba, M.u and Backer, J.M. and Backues, S.K. and Bae, D.H. and Bae, O.N. and Bae, S.H. and Baehrecke, 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Acta Physiologica 231 (1): e13479. January 2021

State of the art approach to managing angina and ischemia: tailoring treatment to the evidence.
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European Journal of Internal Medicine 92 : 40-47. October 2021

The role of centrosome distal appendage proteins (DAPs) in nephronophthisis and ciliogenesis.
Mansour, F. and Boivin, F.J. and Shaheed, I.B. and Schueler, M. and Schmidt-Ott, K.M.
International Journal of Molecular Sciences 22 (22): 12253. 12 November 2021

Induced neurons from germ cells in Caenorhabditis elegans.
Marchal, I. and Tursun, B.
Frontiers in Neuroscience 15 : 771687. 3 December 2021

Lipid metabolite biomarkers in cardiovascular disease: discovery and biomechanism translation from human studies.
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Metabolites 11 (9): 621. September 2021

Ernährung und Hypertonie : Worauf man neben der medikamentösen Therapie achten sollte [Nutrition and hypertension : what one should pay attention to in addition to the pharmaceutical treatment].
McParland, V. and Wilck, N.
Internist 62 (3): 269-276. March 2021

Single-cell genomics to study developmental cell fate decisions in zebrafish.
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Briefings in Functional Genomics 20 (6): 420–426. November 2021

Cardiovascular magnetic resonance in women with cardiovascular disease: position statement from the Society for Cardiovascular Magnetic Resonance (SCMR).
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Cardiovascular magnetic resonance for patients with COVID-19.
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Artificial intelligence extension of the OSCAR-IB criteria.
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Annals of Clinical and Translational Neurology 8 (7): 1528-1542. July 2021

Acute atherosis lesions at the fetal-maternal border: current knowledge and implications for maternal cardiovascular health.
Pitz Jacobsen, D. and Fjeldstad, H.E. and Johnsen, G.M. and Fosheim, I.K. and Moe, K. and Alnæs-Katjavivi, P. and Dechend, R. and Sugulle, M. and Staff, A.C.
Frontiers in Immunology 12 : 791606. 14 December 2021

RNA dynamics in Alzheimer’s disease.
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Molecules 26 (17): 5113. 1 September 2021

Viruses and endogenous retroviruses as roots for neuroinflammation and neurodegenerative diseases.
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Frontiers in Neuroscience 15 : 648629. 12 March 2021

Charting a DNA repair roadmap for immunoglobulin class switch recombination.
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Trends in Biochemical Sciences 46 (3): 184-199. March 2021

Cardiometabolic HFpEF: mechanisms and therapies.
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Metabolic inflammation in heart failure with preserved ejection fraction.
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Bacterial metabolites and cardiovascular risk in children with chronic kidney disease.
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Molecular and Cellular Pediatrics 8 (1): 17. 22 October 2021

The SUMO pathway in pancreatic cancer: insights and inhibition.
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British Journal of Cancer 124 (3): 531-538. 2 February 2021

Rationale for MYC imaging and targeting in pancreatic cancer.
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Kidney physiology and susceptibility to acute kidney injury: implications for renoprotection.
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Nature Reviews Nephrology 17 (5): 335-349. May 2021

Local cyclic adenosine monophosphate signalling cascades - roles and targets in chronic kidney disease.
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Acta Physiologica 232 (1): e13641. May 2021

A window into the future? MRI for evaluation of neuromyelitis optica spectrum disorder throughout the disease course.
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Light sheet fluorescence microscopy.
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Nature Reviews Methods Primers 1 (1): 73. 3 November 2021

The ubiquitin-proteasome system and autophagy: self-digestion for metabolic health.
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Trends in Endocrinology and Metabolism 32 (8): 594-608. August 2021

Potential effects of nutraceuticals in retinopathy of prematurity.
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Myocarditis and inflammatory cardiomyopathy: current evidence and future directions.
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Nature Reviews Cardiology 18 (3): 169-193. March 2021

Opportunities and challenges in global quantification of RNA-protein interaction via UV cross-linking.
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Frontiers in Molecular Biosciences 8 : 669939. 13 May 2021

An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
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Heart failure with preserved ejection fraction in humans and mice: embracing clinical complexity in mouse models.
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Transcriptional mechanisms of pancreatic β-cell maturation and functional adaptation.
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Trends in Endocrinology and Metabolism 32 (7): 474-487. July 2021

A systematic review and meta- analysis of green-light laser vaporization for superficial bladder cancer.
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Regulating muscle spindle and Golgi tendon organ proprioceptor phenotypes.
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Current Opinion in Physiology 19 : 204-210. February 2021

Hallmarks and detection techniques of cellular senescence and cellular ageing in immune cells.
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An introduction to advanced targeted acquisition methods.
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Molecular & Cellular Proteomics 20 : 100165. 18 October 2021

The role of microbiota in primary sclerosing cholangitis and related biliary malignancies.
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International Journal of Molecular Sciences 22 (13): 6975. 1 July 2021


Cerebral EBV-positive PTLD controlled by PD-1 checkpoint blockade in a liver transplant patient.
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Leukemia & Lymphoma 62 (8): 2026-2029. August 2021

Gene expression profiling predicts sensitivity of chronic lymphocytic leukemia cells to dasatinib.
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HemaSphere 5 (1): e514. January 2021

Retinal INL thickness in multiple sclerosis: a mere marker of neurodegeneration?
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Annals of Neurology 89 (1): 192-193. January 2021

Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.
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Molecular Cancer 20 (1): 129. 21 October 2021

Genome sequencing in myeloid cancers.
Dolnik, A. and Schrezenmeier, J. and Bullinger, L.
New England Journal of Medicine 384 (25): e106. 24 June 2021

Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene-edited human-induced pluripotent stem cell-derived cardiomyocytes and preclinical drug screening.
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Clinical and Translational Medicine 11 (12): e646. 26 December 2021

Long-term effects of COVID-19 on kidney function.
Enghard, P. and Hardenberg, J.H. and Stockmann, H. and Hinze, C. and Eckardt, K.U. and Schmidt-Ott, K.M.
Lancet 397 (10287): 1806-1807. 15 May 2021

Imlifidase as novel treatment strategy in anti-neutrophil cytoplasmic antibody–induced pulmonary-renal syndrome.
Enghard, P. and Zickler, D. and Sonnemann, J. and Schneider, W. and Lurje, G. and Elezkurtaj, S. and Eckardt, K.U. and Schreiber, A.
Kidney International 100 (6): 1344-1345. December 2021

The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing.
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Nature Communications 12 (1): 3153. 26 May 2021

Functional connectivity alterations of striato-cortical circuits in multiple sclerosis.
Jaeger, S. and Paul, F. and Finke, C.
Multiple Sclerosis Journal 27 (9): 1469-1470. 1 August 2021

Humoral and cellular immune responses in SARS-CoV-2 mRNA-vaccinated patients with cancer.
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Cancer Cell 39 (9): 1171-1172. 13 September 2021

Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure.
Michalick, L. and Weidenfeld, S. and Grimmer, B. and Fatykhova, D. and Solymosi, P.D. and Behrens, F. and Dohmen, M. and Brack, M.C. and Schulz, S. and Thomasch, E. and Simmons, S. and Müller-Redetzky, H. and Suttorp, N. and Kurth, F. and Neudecker, J. and Toennies, M. and Bauer, T.T. and Eggeling, S. and Corman, V.M. and Hocke, A.C. and Witzenrath, M. and Hippenstiel, S. and Kuebler, W.M.
European Respiratory Journal 57 (3): 2002384. 11 March 2021

High-dose glucocorticoid treatment of near-fatal Bocavirus lung infection results in rapid recovery.
Obenaus, M. and Schildgen, O. and Schürmann, D. and von Brünneck, A.C. and Janz, M. and Keller, U. and Gebauer, B. and Schilling, J. and Schwartz, S. and Weissbrich, B. and Schneider, T. and Hofmann, J. and Mathas, S.
ERJ Open Research 7 (2): 00060-2021. 12 April 2021

Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia.
Rapaport, F. and Neelamraju, Y. and Baslan, T. and Hassane, D. and Gruszczynska, A. and de Massy, M.R. and Farnoud, N. and Haddox, S. and Lee, T. and Medina-Martinez, J. and Sheridan, C. and Thurmond, A. and Becker, M. and Bekiranov, S. and Carroll, M. and Moses Murdock, H. and Valk, P.J.M. and Bullinger, L. and D’Andrea, R. and Lowe, S.W. and Neuberg, D. and Levine, R.L. and Melnick, A. and Garrett-Bakelman, F.E.
Leukemia 35 (9): 2688-2692. September 2021

Mavacamten favorably impacts cardiac structure in obstructive hypertrophic cardiomyopathy: EXPLORER-HCM CMR substudy analysis.
Saberi, S. and Cardim, N. and Yamani, M.H. and Schulz-Menger, J. and Li, W. and Florea, V. and Sehnert, A.J. and Kwong, R.Y. and Jerosch-Herold, M. and Masri, A. and Owens, A. and Lakdawala, N.K. and Kramer, C.M. and Sherrid, M. and Seidler, T. and Wang, A. and Sedaghat-Hamedani, F. and Meder, B. and Havakuk, O. and Jacoby, D.
Circulation 143 (6): 606-608. 9 February 2021

Longitudinal analysis of primary and secondary factors related to fatigue in multiple sclerosis.
Schließeit, J. and Oertel, F.C. and Cooper, G. and Brandt, A.U. and Bellmann-Strobl, J.
Acta Neurologica Belgica 121 (1): 271-274. February 2021

High rates of long-term renal recovery in survivors of coronavirus disease 2019-associated acute kidney injury requiring kidney replacement therapy.
Stockmann, H. and Hardenberg, J.H.B. and Aigner, A. and Hinze, C. and Gotthardt, I. and Stier, B. and Eckardt, K.U. and Schmidt-Ott, K.M. and Enghard, P.
Kidney International 99 (4): 1021-1022. April 2021


STEM pride: perspectives from transgender, nonbinary, and genderqueer scientists.
Armada-Moreira, A. and Cizauskas, C. and Fleury, G. and Forslund, S.K. and Guthman, E.M. and Hanafiah, A. and Hope, J.M. and Jayasinghe, I. and McSweeney, D. and Young, I.D.
Cell 184 (13): 3352-3355. 24 June 2021

A resource of targeted mutant mouse lines for 5,061 genes.
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Nature Genetics 53 (4): 416-419. April 2021

Generation of 20 human induced pluripotent stem cell lines from patients with focal segmental glomerulosclerosis (FSGS).
Cernoch, J. and Fisch, T. and Fischer, I. and Fischer, K. and Iwanska, A. and Krüger, N. and Küchler, J. and Schaar, C. and Schommer, S. and Telugu, N. and Miller, D. and Fernández Vallone, V. and Kurtz, A. and Reinke, P. and Diecke, S. and Stachelscheid, H.
Stem Cell Research 54 : 102406. July 2021

Targeted diets for the gut microbiota and the potential cardiovascular effects.
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Cardiovascular Research 117 (11): e135–e137. 1 October 2021

Cores laboratories: organization for stem cell technology advancement.
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N2 year in review.
Dalmau, J. and Dalakas, M.C. and Kolson, D.L. and Paul, F. and Zamvil, S.S.
Neurology Neuroimmunology & Neuroinflammation 8 (1): e925. January 2021

Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Divangahi, M. and Aaby, P.r and Khader, S.A. and Barreiro, L.B. and Bekkering, S. and Chavakis, T. and van Crevel, R. and Curtis, N. and DiNardo, A.R. and Dominguez-Andres, J. and Duivenvoorden, R. and Fanucchi, S. and Fayad, Z. and Fuchs, E. and Hamon, M. and Jeffrey, K.L. and Khan, N. and Joosten, L.A.B. and Kaufmann, E. and Latz, E. and Matarese, G. and van der Meer, J.W.M. and Mhlanga, M. and Moorlag, S.J.C.F.M. and Mulder, W.J.M. and Naik, S. and Novakovic, B. and O'Neill, L. and Ochando, J. and Ozato, K. and Riksen, N.P. and Sauerwein, R. and Sherwood, E.R. and Schlitzer, A. and Schultze, J.L. and Sieweke, M.H. and Benn, C.S. and Stunnenberg, H. and Sun, J. and van de Veerdonk, F.L. and Weis, S. and Williams, D.L. and Xavier, R. and Netea, M.G.
Nature Immunology 22 (1): 2-6. January 2021

Involving society in science: Reflections on meaningful and impactful stakeholder engagement in fundamental research.
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EMBO Reports 22 (11): e54000. 4 November 2021

Editorial: Monocyte heterogeneity and function.
Ginhoux, F. and Mildner, A. and Gautier, E.L. and Schlitzer, A. and Jakubzick, C. and Varol, C. and Bain, C. and Guermonprez, P.
Frontiers in Immunology 11 : 626725. 7 January 2021

The need for sustainable leadership in academia : a survey of academics in Germany shows a lack of and a great demand for training in leadership skills.
Haage, V. and Voss, L. and Nguyen, D. and Eggert, F.
EMBO Reports 22 (12): e53592. 6 December 2021

The continued need for animals to advance brain research.
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Neuron 109 (15): 2374-2379. 4 August 2021

Solute excretion, metabolism, and cardio-renoprotection via two distinct mechanisms revolutionize clinical outcomes.
Luft, F.C.
Acta Physiologica 232 (3): e13589. 6 July 2021

Can single nucleotide polymorphisms beat Schnüffel? Assessing hypertension polygenic risk scores.
Luft, F.C.
Hypertension 77 (4): 1128-1132. April 2021

I'm pickin' up good dilations.
Luft, F.C.
Cardiovascular Research 117 (1): 27-28. 1 January 2021

The rise of proteome-wide biophysics.
Mateus, A. and Savitski, M.M. and Piazza, I.
Molecular Systems Biology 17 (7): e10442. July 2021

Niendorf, T. and Pohlmann, A.
Methods in Molecular Biology 2216 : v-vi. 2021

Left ventricular noncompaction is a myocardial phenotype: cardiomyopathy - yes or no?
Oechslin, E. and Jenni, R. and Klaassen, S.
Canadian Journal of Cardiology 37 (3): 366-369. March 2021

Spinal cord and brain MRI should be routinely performed during follow-up in patients with NMOSD - commentary.
Paul, F.
Multiple Sclerosis Journal 27 (1): 16-18. 1 January 2021

BMI and mortality - time to revisit current recommendations for risk assessment.
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American Journal of Clinical Nutrition 113 (1): 3-4. January 2021

Therapy-induced senescence: opportunities to improve anticancer therapy.
Prasanna, P.G. and Citrin, D.E. and Hildesheim, J. and Ahmed, M.M. and Venkatachalam, S. and Riscuta, G. and Xi, D. and Zheng, G. and van Deursen, J. and Goronzy, J. and Kron, S.J. and Anscher, M.S. and Sharpless, N.E. and Campisi, J. and Brown, S.L. and Niedernhofer, L.J. and O'Loghlen, A. and Georgakilas, A.G. and Paris, F. and Gius, D. and Gewirtz, D.A. and Schmitt, C.A. and Abazeed, M.E. and Kirkland, J.L. and Richmond, A. and Romesser, P.B. and Lowe, S.W. and Gil, J. and Mendonca, M.S. and Burma, S. and Zhou, D. and Coleman, C.N.
Journal of the National Cancer Institute 113 (10): 1285-1298. October 2021

Early days of tenascin-R research: two approaches discovered and shed light on tenascin-R.
Rathjen, F.G. and Hodge, R.
Frontiers in Immunology 11 : 612482. 8 January 2021

Mitochondrial bioenergetics and neurodegeneration: a paso doble.
Rossi, A. and Pizzo, P.
Neural Regeneration Research 16 (4): 686-687. April 2021

Career advancement for women in diabetes-related research: developing and retaining female talent.
Sandoval, D.A. and Alonso, L.C. and Gannon, M. and Sander, M. and Sussel, L. and Reusch, J.E.B.
Diabetes Care 44 (8): 1744-1747. August 2021

Canagliflozin and myocardial oxidative stress: SGLT1 inhibition takes centre stage.
Schiattarella, G.G. and Bode, D.
European Heart Journal 42 (48): 4961-4963. 21 December 2021

Metabolism and inflammation in cardiovascular health and diseases: mechanisms to therapies.
Schiattarella, G.G. and Wang, Y. and Tian, R. and Hill, J.A.
Journal of Molecular and Cellular Cardiology 157 : 113-114. August 2021

NEMHESYS - European perspective on the implementation of next-generation sequencing into clinical diagnostics.
Serramito-Gómez, I. and Clarke, K.M. and Rodríguez-Vicente, A.E. and McGimpsey, J.E. and Abáigar, M. and Díez, C.B. and Benito, R. and Bullinger, L. and Mills, K.I. and Hernández Rivas, J.M.
HemaSphere 5 (3): e541. March 2021

Wie das Immunsystem SARS-CoV-2 den Weg ebnet [How the immune system paves the way for SARS-CoV-2].
Sigal, M.
Hygiene und Medizin 46 (3): 22-23. 2021

The EACVI survey on cardiac imaging in cardio-oncology.
Stankovic, I. and Dweck, M.R. and Marsan, N.A. and Bergler-Klein, J. and Holte, E. and Manka, R. and Schulz-Menger, J. and Sitges, M. and Haugaa, K.H.
European Heart Journal - Cardiovascular Imaging 22 (4): 367-371. April 2021

Stein, U.S.
Methods in Molecular Biology 2294 : v. 2021

Novichok nerve agent poisoning.
Steindl, D. and Boehmerle, W. and Körner, R. and Praeger, D. and Haug, M. and Nee, J. and Schreiber, A. and Scheibe, F. and Demin, K. and Jacoby, P. and Tauber, R. and Hartwig, S. and Endres, M. and Eckardt, K.U.
Lancet 397 (10270): 249-252. 16 January 2021

Contribution of preclinical MRI to responsible animal research: living up to the 3R principle.
Wachsmuth, L. and Mensen, A. and Barca, C. and Wiart, M. and Tristão-Pereira, C. and Busato, A. and Waiczies, S. and Himmelreich, U. and Millward, J.M. and Reimann, H.M. and Jelescu, I. and Marzola, P. and Pradier, B. and Viola, A. and Faber, C.
Magnetic Resonance Materials in Physics Biology and Medicine 34 (4): 469-474. August 2021

A multi-omics roadmap of β-cell failure in type 2 diabetes mellitus.
Wang, G. and Sander, M.
Nature Reviews Endocrinology 17 (11): 641-642. November 2021

What's for dinner? Why a close look at diet and microbiota is worthwhile in experimental hypertension research.
Wilck, N.
Acta Physiologica 232 (4): e13704. August 2021

SARS-CoV-2 effects on the renin-angiotensin-aldosterone system, therapeutic implications.
Ye, Q. and Lai, E.Y. and Luft, F.C. and Persson, P.B. and Mao, J.
Acta Physiologica 231 (4): e13608. April 2021


Accelerating clinical research in neuromyelitis optica spectrum disorders.
Oertel, F.C. and Paul, F.
Clinical and Experimental Neuroimmunology 12 (2): 89-91. May 2021

An atlas for unveiling the functional organization of spinal circuits.
Toscano, E. and Zampieri, N.
Cell Reports Methods 1 (5): 100086. 27 September 2021


Rapid nuclear deadenylation of mammalian messenger RNA.
Alles, J. and Legnini, I. and Pacelli, M. and Rajewsky, N.
bioRxiv : 2021.11.16.468655. 18 November 2021

In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation.
Anania, C. and Acemel, R.D. and Jedamzick, J. and Bolondi, A. and Cova, G. and Brieske, N. and Kuehn, R. and Wittler, L. and Real, F.M. and Lupianez, D.G.
bioRxiv : 2021.04.14.439779. 14 April 2021

ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling.
Asaro, A. and Sinha, R. and Bakun, M. and Kalnytska, O. and Carlo-Spiewok, A.S. and Rubel, T. and Rozeboom, A. and Dadlez, M. and Kaminska, B. and Aronica, E. and Malik, A.R. and Willnow, T.E.
bioRxiv : 2021.05.20.444938. 20 May 2021

RS-FISH: Precise, interactive, fast, and scalable FISH spot detection.
Bahry, E. and Breimann, L. and Zouinkhi, M. and Epstein, L. and Kolyvanov, K. and Long, X. and Harrington, K.I.S. and Lionnet, T. and Preibisch, S.
bioRxiv : 2021.03.09.434205v2. 18 October 2021

SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics.
Baytek, G. and Blume, A. and Gerceker Demirel, F. and Bulut, S. and Mertins, P. and Tursun, B.
bioRxiv : 2021.02.14.431134. 14 February 2021

The single-cell transcriptional landscape of lung carcinoid tumors.
Bischoff, P. and Trinks, A. and Wiederspahn, J. and Obermayer, B. and Pett, J.P. and Jurmeister, P. and Elsner, A. and Dziodzio, T. and Rückert, J.C. and Neudecker, J. and Falk, C. and Beule, D. and Sers, C. and Morkel, M. and Horst, D. and Klauschen, F. and Blüthgen, N.
bioRxiv : 2021.12.07.471416. 8 December 2021

The H4K20 demethylase DPY-21 regulates the dynamics of condensin DC binding.
Breimann, L. and Morao, A.K. and Kim, J. and Jimenez, D. and Maryn, N. and Bikkasani, K. and Carrozza, M.J. and Albritton, S.E. and Kramer, M. and Street, L.A. and Cerimi, K. and Schumann, V.F. and Bahry, E. and Preibisch, S. and Woehler, A. and Ercan, S.
bioRxiv : 2021.04.11.438056. 24 September 2021

Immune competence and spleen size scale with colony status in the naked mole-rat.
Bégay, V. and Cirovic, B. and Barker, A.J. and Klopfleisch, R. and Hart, D.W. and Bennett, N.C. and Lewin, G.R.
bioRxiv : 2021.08.15.456351. 15 August 2021

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules.
Cipriani, P.G. and Bay, O. and Zinno, J.P. and Gutwein, M. and Gan, H.H. and Mayya, V. and Chung, G. and Chen, J.X. and Fahs, H. and Guan, Y. and Duchaine, T. and Selbach, M. and Piano, F. and Gunsalus, K.
bioRxiv : 2021.06.17.448425. 17 June 2021

Svep1 stabilizes developmental vascular anastomosis in reduced flow conditions.
Coxam, B. and Padberg, Y. and Maier, K. and Jung, S. and Bartels-Klein, E. and Szymborska, A. and Finotto, L. and Schulte-Merker, S. and Gerhardt, H.
bioRxiv : 2021.03.13.435246. 19 March 2021

An executive center for the intake of liquids.
Dempsey, B. and Sungeelee, S. and Bokiniec, P. and Chettouh, Z. and Diem, S. and Autran, S. and Harrell, E.R. and Poulet, J.F.A. and Birchmeier, C. and Carrey, H. and Genovesio, A. and McMullan, S. and Goridis, C. and Fortin, G. and Brunet, J.F.
bioRxiv : 2021.07.02.450862. 4 July 2021

Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data.
Dimchev, G. and Amiri, B. and Fäßler, F. and Falcke, M. and Schur, F.K.M.
bioRxiv : 2021.05.25.445599. 25 May 2021

Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.
Dorel, M. and Klinger, B. and Mari, T. and Toedling, J. and Blanc, E. and Messerschmidt, C. and Nadler-Holly, M. and Ziehm, M. and Sieber, A. and Hertwig, F. and Beule, D. and Eggert, A. and Schulte, J.H. and Selbach, M. and Blüthgen, N.
bioRxiv : 2021.06.14.448322. 14 June 2021

Mechanical forces switch blood vessel subtypes to arrest adolescent bone growth.
Dzamukova, M. and Brunner, T.M. and Miotla-Zarebska, J. and Heinrich, F. and Brylka, L. and Mashreghi, M.F. and Kusumbe, A. and Kühn, R. and Schinke, T. and Vincent, T. and Löhning, M.
Research Square : rs.3.rs-120475. 12 January 2021

Complex population dynamics in a spatial microbial ecosystem with Physarum polycephalum.
Epstein, L. and Dubois, Z. and Smith, J. and Lee, Y. and Harrington, K.
bioRxiv : 2021.03.14.435300. 15 March 2021

Predicting brain-age from raw T(1)-weighted magnetic resonance imaging data using 3D convolutional neural networks.
Fisch, L. and Ernsting, J. and Winter, N.R. and Holstein, V. and Leenings, R. and Beisemann, M. and Sarink, K. and Emden, D. and Opel, N. and Redlich, R. and Repple, J. and Grotegerd, D. and Meinert, S. and Wulms, N. and Minnerup, H. and Hirsch, J.G. and Niendorf, T. and Endemann, B. and Bamberg, F. and Kröncke, T. and Peters, A. and Bülow, R. and Völzke, H. and von Stackelberg, O. and Sowade, R.F. and Umutlu, L. and Schmidt, B. and Caspers, S. and Kugel, H. and Baune, B.T. and Kircher, T. and Risse, B. and Dannlowski, U. and Berger, K. and Hahn, T.
arXiv : 2103.11695. 22 March 2021

The SEQC2 Epigenomics Quality Control (EpiQC) Study: comprehensive characterization of epigenetic methods, reproducibility, and quantification.
Foox, J. and Nordlund, J. and Lalancette, C. and Gong, T. and Lacey, M. and Lent, S. and Langhorst, B.W. and Ponnaluri, V.K.C. and Williams, L. and Padmamabhan, K. and Cavalcante, R. and Lundmark, A. and Butler, D. and Gurvitch, J. and Greally, J.M. and Suzuki, M. and Menor, M. and Nasu, M. and Alonso, A. and Sheridan, C. and Scherer, A. and Bruinsma, S. and Golda, G. and Muszynska, A. and Labaj, P.P. and Campbe, M.A. and Wos, F. and Raine, A. and Liljedahl, U. and Axelsson, T. and Wang, C. and Chen, Z. and Yang, Z. and Li, J. and Yang, X. and Wang, H. and Melnick, A. and Guo, S. and Blume, A. and Franke, V. and Ibanez de Caceres, I. and Rodriguez-Antolin, C. and Rosas, R. and Wade Davis, J. and Ishii, J. and Megherbi, D.B. and Xiao, W. and Liao, W. and Xu, J. and Hong, H. and Ning, B. and Tong, W. and Akalin, A. and Wang, Y. and Wang, Y. and Mason, C.E.
bioRxiv : 2020.12.14.421529. 26 April 2021

Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and aging.
Freitag, K. and Eede, P. and Ivanov, A. and Schneeberger, S. and Borodina, T. and Sauer, S. and Beule, D. and Heppner, F.L.
bioRxiv : 2021.08.02.454573v1. 28 November 2021

Complement activation induces excessive T cell cytotoxicity in severe COVID-19.
Georg, P. and Astaburuaga-García, R. and Bonaguro, L. and Brumhard, S. and Michalick, L. and Lippert, L.J. and Kostevc, T. and Gäbel, C. and Schneider, M. and Streitz, M. and Demichev, V. and Gemünd, I. and Barone, M. and Tober-Lau, P. and Helbig, E.T. and Stein, J. and Dey, H.P. and Paclik, D. and Mülleder, M. and Aulakh, S.K. and Mei, H.E. and Schulz, A.R. and Hippenstiel, S. and Corman, V.M. and Beule, D. and Wyler, E. and Landthaler, M. and Obermayer-Wasserscheid, B. and Boor, P. and Demir, M. and Wesselmann, H. and Suttorp, N. and Uhrig, A. and Müller-Redetzky, H. and Nattermann, J. and Kuebler, W.M. and Meisel, C. and Ralser, M. and Schultze, J.L. and Aschenbrenner, A.C. and Thibeault, C. and Kurth, F. and Sander, L.E. and Blüthgen, N. and Sawitzki, B.
medRxiv : 2021.06.08.21258481. 11 June 2021

Assessing genome-wide dynamic changes in enhancer activity during early mESC differentiation by FAIRE-STARR-seq.
Glaser, L.V. and Steiger, M. and Fuchs, A. and van Bömmel, A. and Einfeldt, E. and Chung, H.R. and Vingron, M. and Meijsing, S.H.
bioRxiv : 2021.06.04.446899. 6 June 2021

Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O. and Zincke, F. and Eckert, A. and Kobelt, D. and Preissner, S. and Liebeskind, J.M. and Gunkel, N. and Putzker, K. and Lewis, J. and Preissner, S. and Kortüm, B. and Walther, W. and Mura, C. and Bourne, P.E. and Stein, U. and Preissner, R.
medRxiv : 2021.07.20.21260891. 22 July 2021

Timed global reorganization of protein synthesis during neocortex neurogenesis at codon resolution.
Harnett, D. and Ambrozkiewicz, M.C. and Zinnall, U. and Borisova, E. and Rusanova, A. and Dannenberg, R. and Imami, K. and Münster-Wandowski, A. and Fauler, B. and Mielke, T. and Selbach, M. and Landthaler, M. and Spahn, C.M.T. and Tarabykin, V. and Ohler, U. and Kraushar, M.L.
bioRxiv : 2021.06.23.449626. 24 June 2021

Dual-color fluorescence cross-correlation spectroscopy to study protein-protein interaction and protein dynamics in live cells.
Hemmen, K. and Choudhury, S. and Friedrich, M. and Balkenhol, J. and Knote, F. and Lohse, M. and Heinze, K.G.
bioRxiv : 2021.09.10.459760v1. 12 September 2021

Expression of a modified astrocytic glutamate transporter alleviates Huntington’s hypokinesia, promotes synaptic glutamate clearance and counteracts potentially adverse EAAT2 interactions.
Hirschberg, S. and Dvorzhak, A. and Rasooli-Nejad, S.M.A. and Angelov, S. and Kirchner, M. and Mertins, P. and Lättig-Tünnemann, G. and Harms, C. and Schmitz, D. and Grantyn, R.
bioRxiv : 2020.09.17.302158. 26 March 2021

Cellular drivers of injury response and regeneration in the adult zebrafish heart.
Hu, B. and Lelek, S. and Spanjaard, B. and Simões, M.G. and Aliee, H. and Schäfer, R. and Theis, F. and Panáková, D. and Junker, J.P.
bioRxiv : 2021.01.07.425670. 7 January 2021

The gut microbiota is associated with the small intestinal paracellular permeability and the development of the immune system in healthy children during the first two years of life.
Kaczmarczyk, M. and Löber, U. and Adamek, K. and Węgrzyn, D. and Skonieczna-Żydecka, K. and Malinowski, D. and Łoniewski, I. and Markó, L. and Ulas, T. and Forslund, S.K. and Łoniewska, B.
Research Square : rs.3.rs-154335/v1. 29 January 2021

Fast, efficient and virus-free generation of TRAC-replaced CAR T cells.
Kath, J. and Du, W. and Thommandru, B. and Turk, R. and Amini, L. and Stein, M. and Zittel, T. and Martini, S. and Ostendorf, L. and Wilhelm, A. and Akyuez, L. and Rehm, A. and Hoepken, U.E. and Pruss, A. and Kuenkele, A. and Jacobi, A.M. and Volk, H.D. and Schmueck-Henneresse, M. and Reinke, P. and Wagner, D.L.
bioRxiv : 2021.02.14.431017. 14 February 2021

MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution.
Kaufmann, T.L. and Petkovic, M. and Watkins, T.B.K. and Colliver, E.C. and Laskina, S. and Thapa, N. and Minussi, D.C. and Navin, N. and Swanton, C. and Van Loo, P. and Haase, K. and Tarabichi, M. and Schwarz, R.F.
bioRxiv : 2021.02.28.433227. 6 September 2021

Chronic COVID-19 Syndrome and Chronic Fatigue Syndrome (ME/CFS) following the first pandemic wave in Germany - a first analysis of a prospective observational study.
Kedor, C. and Freitag, H. and Meyer-Arndt, L. and Wittke, K. and Zoller, t. and Steinbeis, F. and Haffke, M. and Gordon, R. and Heidecker, B. and Volk, H.D. and Skurk, C. and Paul, F. and Bellmann-Strobl, J. and Scheibenbogen, C.
medRxiv : 2021.02.06.21249256. 8 February 2021

Simultaneous dimensionality reduction and integration for single-cell ATAC-seq data using deep learning.
Kopp, W. and Akalin, A. and Ohler, U.
bioRxiv : 2021.05.11.443540. 12 May 2021

Principles of ecDNA random inheritance drive rapid genome change and therapy resistance in human cancers.
Lange, J.T. and Chen, C.Y. and Pichugin, Y. and Xie, L. and Tang, J. and Hung, K.L. and Yost, K.E. and Shi, Q. and Erb, M.L. and Rajkumar, U. and Wu, S. and Swanton, C. and Liu, Z. and Huang, W. and Chang, H.Y. and Bafna, V. and Henssen, A.G. and Werner, B. and Mischel, P.S.
bioRxiv : 10.1101/2021.06.11.447968. 11 June 2021

N-myristoyltransferase inhibition is synthetic lethal in MYC-deregulated cancers.
Lueg, G.A. and Faronato, M. and Gorelik, A. and Grocin, A.G. and Caamano-Gutierrez, E. and Falciani, F. and Solari, R. and Carr, R. and Bell, A.S. and Bartlett, E. and Hutton, J.A. and Llorian-Sopena, M. and Chakravarty, P. and Brzezicha, B. and Janz, M. and Garnett, M.J. and Calado, D.P. and Tate, E.W.
bioRxiv : 2021.03.20.436222. 20 March 2021

Optogenetic silencing of neurotransmitter release with a naturally occurring invertebrate rhodopsin.
Mahn, M. and Saraf-Sinik, I. and Patil, P. and Pulin, M. and Bitton, E. and Karalis, N. and Bruentgens, F. and Palgi, S. and Gat, A. and Dine, J. and Wietek, J. and Davidi, I. and Levy, R. and Litvin, A. and Zhou, F. and Sauter, K. and Soba, P. and Schmitz, D. and Luthi, A. and Rost, B.R. and Wiegert, J.S. and Yizhar, O.
bioRxiv : 2021.02.18.431673. 18 February 2021

PatchPerPixMatch for automated 3d search of neuronal morphologies in light microscopy.
Mais, L. and Hirsch, P. and Managan, C. and Wang, K. and Rokicki, K. and Svirskas, R.R. and Dickson, B.J. and Korff, W. and Rubin, G.M. and Ihrke, G. and Meissner, G.W. and Kainmueller, D.
bioRxiv : 2021.07.23.453511. 26 July 2021

Automated reconstruction of whole-embryo cell lineages by learning from sparse annotations.
Malin-Mayor, C. and Hirsch, P. and Guignard, L. and McDole, K. and Wan, Y. and Lemon, W.C. and Keller, P.J. and Preibisch, S. and Funke, J.
bioRxiv : 2021.07.28.454016. 29 July 2021

Disrupting the CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
Marino, S.F. and Jerke, U. and Rolle, S. and Daumke, O. and Kettritz, R.
bioRxiv : 2021.05.17.444335. 17 May 2021

Emerging single cell endothelial heterogeneity supports sprouting tumour angiogenesis and growth.
Matsumoto, K. and Rambow, F. and Stanchi, F. and Mathivet, T. and Qian, J. and Giese, W. and He, L. and Lambrechts, D. and Zhou, B. and Betsholtz, C. and Marine, J.C. and Gerhardt, H.
bioRxiv : 2021.06.09.447719. 11 June 2021

The Cl(-)-channel TMEM16A controls the generation of cochlear Ca(2+) waves and promotes the refinement of auditory brainstem networks.
Maul, A. and Jovanovic, S. and Huebner, A.K. and Strenzke, N. and Moser, T. and Rübsamen, R. and Hübner, C.A.
bioRxiv : 2021.07.05.451099. 5 July 2021

Mitochondrial variant enrichment from high-throughput single-cell RNA-seq resolves clonal populations.
Miller, T.E. and Lareau, C.A. and Verga, J.A. and Ssozi, D. and Ludwig, L.S. and El Farran, C. and Griffin, G.K. and Lane, A.A. and Bernstein, B.E. and Sankaran, V.G. and van Galen, P.
bioRxiv : 2021.03.08.434450. 9 March 2021

A community-driven roadmap to advance research on translated open reading frames detected by Ribo-seq.
Mudge, J.M. and Ruiz-Orera, J. and Prensner, J.R. and Brunet, M.A. and Gonzalez, J.M. and Magrane, M. and Martinez, T. and Schulz, J.F. and Yang, Y.T. and Albà, M.M. and Baranov, P.V. and Bazzini, A. and Bruford, E. and Martin, M.J. and Carvunis, A.R. and Chen, J. and Couso, J.P. and Flicek, P. and Frankish, A. and Gerstein, M. and Hubner, N. and Ingolia, N.T. and Menschaert, G. and Ohler, U. and Roucou, X. and Saghatelian, A. and Weissman, J. and van Heesch, S.
bioRxiv : 2021.06.10.447896. 10 June 2021

AI-driven Deep Visual Proteomics defines cell identity and heterogeneity.
Mund, A. and Coscia, F. and Hollandi, R. and Kovács, F. and Kriston, A. and Brunner, A.D. and Bzorek, M. and Naimy, S. and Rahbek Gjerdrum, L.M. and Dyring-Andersen, B. and Bulkescher, J. and Lukas, C. and Gnann, C. and Lundberg, E. and Horvath, P. and Mann, M.
bioRxiv : 2021.01.25.427969. 27 January 2021

Longitudinal omics in Syrian hamsters integrated with human data unravel cellular effector responses to moderate COVID-19.
Nouailles, Geraldine and Wyler, E. and Pennitz, P. and Postmus, D. and Vladrimirova, D. and Kazmierski, J. and Pott, F. and Dietert, K. and Mülleder, M.l and Farztdinov, V. and Obermayer, B. and Wienhold, S.M. and Andreotti, S. and Hoefler, T. and Sawitzki, B. and Drosten, C. and Sander, L. and Suttorp, N. and Ralser, M. and Beule, D. and Gruber, A. and Goffinet, C. and Landthaler, M. and Trimpert, J. and Witzenrath, M.
Research Square : rs-148392/v1. 28 January 2021

Urbanization promotes specific bacteria in freshwater microbiomes including potential pathogens.
Numberger, D. and Zoccarato, L. and Woodhouse, J. and Ganzert, L. and Sauer, S. and Grossart, H.P. and Greenwood, A.D.
bioRxiv : 2020.06.26.173328. 8 November 2021

Uncharted biosynthetic potential of the ocean microbiome.
Paoli, L. and Ruscheweyh, H.J. and Forneris, C.C. and Kautsar, S. and Clayssen, Q. and Salazar, G. and Milanese, A. and Gehrig, D. and Larralde, M. and Carroll, L.M. and Sánchez, P. and Zayed, A.A. and Cronin, D.R. and Acinas, S.G. and Bork, P. and Bowler, C. and Delmont, T.O. and Sullivan, M.B. and Wincker, P. and Zeller, G. and Robinson, S.L. and Piel, J. and Sunagawa, S.
bioRxiv : 2021.03.24.436479. 24 March 2021

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.
Pekayvaz, K. and Leunig, A. and Kaiser, R. and Brambs, S. and Joppich, M. and Janjic, A. and Popp, O. and Polewka, V. and Wange, L.E. and Gold, C. and Kirchner, M. and Muenchhoff, M. and Hellmuth, J.C. and Scherer, C. and Eser, T. and Deák, F. and Kuhl, N. and Linder, A. and Saar, K. and Tomas, L. and Schulz, C. and Enard, W. and Kroidl, I. and Geldmacher, C. and von Bergwelt-Baildon, M. and Keppler, O.T. and Zimmer, R. and Mertins, P. and Hubner, N. and Hölscher, M. and Massberg, S. and Stark, K. and Nicolai, L.
bioRxiv : 2021.02.03.429351. 3 February 2021

Engineering, decoding and systems-level characterization of chimpanzee cytomegalovirus.
Phan, Q.V. and Bogdanow, B. and Wyler, E. and Landthaler, M. and Liu, F. and Hagemeier, C. and Wiebusch, L.
bioRxiv : 2021.07.20.453063. 20 July 2021

Rabies anterograde monosynaptic tracing reveals organization of spinal sensory circuits.
Pimpinella, S. and Zampieri, N.
bioRxiv : 429920. 11 February 2021

Single-cell transcriptomic analysis of antiviral responses and viral antagonism in Chikungunya virus-infected synovial fibroblasts.
Pott, F. and Postmus, D. and Brown, R.J.P. and Wyler, E. and Neumann, E. and Landthaler, M. and Goffinet, C.
bioRxiv : 2020.06.07.138610. 11 June 2021

PiggyBac transposable element-derived 1 controls neuronal progenitor identity, stress sensing and mammal-specific paraspeckles.
Raskó, T. and Pande, A. and Radscheit, K. and Zink, A. and Singh, M. and Sommer, C. and Wachtl, G. and Kolacsek, O. and Inak, G. and Szvetnik, A. and Petrakis, S. and Bunse, M. and Bansal, V. and Selbach, M. and Orbán, T. and Prigione, A. and Hurst, L.D. and Izsvák, Z.
bioRxiv : 2021.05.19.444448. 19 May 2021

Investigating the concept of accessibility for predicting novel RNA-RNA interactions.
Reißer, S. and Meyer, I.M.
bioRxiv : 2021.06.03.446902. 3 June 2021

Brain disconnectome mapping and serum neurofilament light levels in multiple sclerosis.
Rise, H.H. and Brune, S. and Chien, C. and Berge, T. and Bos, S.D. and Andorrà, M. and Valdeolivas, I.P. and Beyer, M.K. and Sowa, P. and Scheel, M. and Brandt, A.U. and Asseyer, S. and Blennow, K. and Pedersen, M.L. and Zetterberg, H. and Thiebaut de Schotten, M. and Cellerino, M. and Uccelli, A. and Paul, F. and Villoslada, P. and Harbo, H.F. and Westlye, L.T. and Høgestøl, E.A.
medRxiv : 2021.04.21.21255887. 27 April 2021

On the distribution of spinal premotor interneurons.
Ronzano, R. and Skarlatou, S. and Bannatyne, B.A. and Bhumbra, G.S. and Foster, J.D. and Lancelin, C. and Pocratsky, A. and Ozyurt, M.G. and Smith, C.C. and Todd, A.J. and Maxwell, D.J. and Murray, A.J. and Brownstone, R.M. and Zampieri, N. and Beato, M.
bioRxiv : 2021.02.10.430608. 11 February 2021

Neurodegeneration in human brain organoids infected with herpes simplex virus type 1.
Rybak-Wolf, A. and Wyler, E. and Legnini, I. and Loewa, A. and Glažar, P. and Kim, S.J. and Pentimalli, T.M. and Oliveras Martinez, A. and Beyersdorf, B. and Woehler, A. and Landthaler, M. and Rajewsky, N.
bioRxiv : 2021.03.05.434122. 7 March 2021

Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance.
Schlautmann, L.P. and Boehm, V. and Lackmann, J.W. and Altmüller, J. and Dieterich, C. and Gehring, N.H.
bioRxiv : 2021.08.20.457088. 20 August 2021

Drivers and determinants of strain dynamics following faecal microbiota transplantation.
Schmidt, T.S.B. and Li, S.S. and Maistrenko, O.M. and Akanni, W. and Coelho, L.P. and Dolai, S. and Fullam, A. and Glazek, A.M. and Hercog, R. and Herrema, H. and Jung, F. and Kandels, S. and Orakov, A. and Van Rossum, T. and Benes, V. and Borody, T.J. and de Vos, W.M. and Ponsioen, C.Y. and Nieuwdorp, M. and Bork, P.
bioRxiv : 2021.09.30.462010. 30 September 2021

The neuroinflammatory interleukin-12 signaling pathway drives Alzheimer's disease-like pathology by perturbing oligodendrocyte survival and neuronal homeostasis.
Schneeberger, S. and Kim, S.J. and Eede, P. and Boltengagen, A. and Braeuning, C. and Andreadou, M. and Becher, B. and Karaiskos, N. and Kocks, C. and Rajewsky, N. and Heppner, F.L.
bioRxiv : 2021.04.25.441313. 27 April 2021

Multifunctional RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes.
Schneider-Lunitz, V. and Ruiz-Orera, J. and Hubner, N. and van Heesch, S.
bioRxiv : 2021.04.13.439465. 6 July 2021

Dual-function RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes.
Schneider-Lunitz, V. and Ruiz-Orera, J. and Hubner, N. and van Heesch, S.
bioRxiv : 2021.04.13.439465. 13 April 2021

On the relation between input and output distributions of scRNA-seq experiments.
Schwabe, D. and Falcke, M.
bioRxiv : 2021.10.08.463628v1. 9 October 2021

Thrifty energy phenotype predicts weight regain - results of a randomized controlled trial.
Spranger, L. and Bredow, J. and Zeitz, U. and Grittner, U. and Boschmann, M. and Dickmann, S. and Stobäus, N. and Jumpertz-von Schwartzenberg, R. and Spranger, J. and Mai, K.
medRxiv : 2021.03.25.21254300. 26 March 2021

CYCLeR - a novel tool for the full isoform assembly and quantification of circRNAs.
Stefanov, S.R. and Meyer, I.M.
bioRxiv : 2021.04.27.441578. 28 April 2021

Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors.
Thibado, J. and Tano, J.Y. and Lee, J. and Salas-Estrada, L. and Provasi, D. and Strauss, A. and Lamim Ribeiro, J.M. and Xiang, G. and Broichhagen, J. and Filizola, M. and Lohse, M. and Levitz, J.
bioRxiv : 2021.02.04.429701. 6 February 2021

Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states.
Triana, S.H. and Vonficht, D. and Jopp-Saile, L. and Raffel, S. and Lutz, R. and Leonce, D. and Ordoñez-Rueda, D. and Ramasz, B. and Boch, T. and Jann, J.C. and Nowak, D. and Hofmann, W.K. and Müller-Tidow, C. and Hübschmann, D. and Alexandrov, T. and Benes, V. and Trumpp, A. and Paulsen, M. and Velten, L. and Haas, S.
bioRxiv : 2021.03.18.435922. 2 September 2021

Insulin mRNA is stored in RNA granules in resting beta cells.
Vasiljević, J. and Vasiljević, D. and Ganß, K. and Sönmez, A. and Wegbrod, C. and Quezada, E. and Münster, C. and Schöniger, E. and Friedland, D. and Kipke, N. and Distler, M. and Selbach, M. and Solimena, M.
bioRxiv : 2021.05.07.443159. 29 June 2021

Proteome-wide quantitative RNA interactome capture (qRIC) identifies phosphorylation sites with regulatory potential in RBM20.
Vieira-Vieira, C.H. and Dauksaite, V. and Gotthardt, M.