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Impaired human hematopoiesis due to a cryptic intronic splicing mutation.
Abdulhay, N.J. and Fiorini, C. and Verboon, J.M. and Ludwig, L.S. and Ulirsch, J.C. and Zieger, B. and Lareau, C.A. and Mi, X. and Roy, A. and Obeng, E.A. and Erlacher, M. and Gupta, N. and Gabriel, S.B. and Ebert, B.L. and Niemeyer, C.M. and Khoriaty, R.N. and Ancliff, P. and Gazda, H.T. and Wlodarski, M.W. and Sankaran, V.G.
Journal of Experimental Medicine 216
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6 May 2019
Critical role for piccolo in synaptic vesicle retrieval.
Ackermann, F. and Schink, K.O. and Bruns, C. and Izsvák, Z. and Hamra, F.K. and Rosenmund, C. and Garner, C.C.
eLife 8
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10 May 2019
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.
Ackermann, T. and Hartleben, G. and Müller, C. and Mastrobuoni, G. and Groth, M. and Sterken, B.A. and Zaini, M.A. and Youssef, S.A. and Zuidhof, H.R. and Krauss, S.R. and Kortman, G. and de Haan, G. and de Bruin, A. and Wang, Z.Q. and Platzer, M. and Kempa, S. and Calkhoven, C.F.
Communications Biology 2
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14 June 2019
Development of robust 17(R),18(S)-epoxyeicosatetraenoic acid (17,18-EEQ) analogues as potential clinical antiarrhythmic agents.
Adebesin, A.M. and Wesser, T. and Vijaykumar, J. and Konkel, A. and Paudyal, M. and Lossie, J. and Zhu, C. and Westphal, C. and Puli, N. and Fischer, R. and Schunck, W.H. and Falck, J.
Journal of Medicinal Chemistry 62
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27 November 2019
A novel non-invasive method to detect RELM beta transcript in gut barrier related changes during a gastrointestinal nematode infection.
Ahmed, N. and Heitlinger, E. and Affinass, N. and Kühl, A.A. and Xenophontos, N. and Jarquin, V.H. and Jost, J. and Steinfelder, S. and Hartmann, S.
Frontiers in Immunology 10
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March 2019
Lifestyle interventions in Muslim patients with metabolic syndrome: a feasibility study.
Aktas, M.F. and Mähler, A. and Hamm, M. and Perger, G. and Simon, F. and Westenhöfer, J. and Luft, F.C. and Boschmann, M.
European Journal of Clinical Nutrition 73
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May 2019
RIKADA study reveals risk factors in pediatric primary cardiomyopathy.
Al-Wakeel-Marquard, N. and Degener, F. and Herbst, C. and Kühnisch, J. and Dartsch, J. and Schmitt, B. and Kuehne, T. and Messroghli, D. and Berger, F. and Klaassen, S.
Journal of the American Heart Association 8
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6 August 2019
Quantification and characterization of radical production in human, animal and 3D skin models during sun irradiation measured by EPR spectroscopy.
Albrecht, S. and Elpelt, A. and Kasim, C. and Reble, C. and Mundhenk, L. and Pischon, H. and Hedtrich, S. and Witzel, C. and Lademann, J. and Zastrow, L. and Beckers, I. and Meinke, M.C.
Free Radical Biology and Medicine 131
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1 February 2019
Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids.
Alcala, N. and Leblay, N. and Gabriel, A.A.G. and Mangiante, L. and Hervas, D. and Giffon, T. and Sertier, A.S. and Ferrari, A. and Derks, J. and Ghantous, A. and Delhomme, T.M. and Chabrier, A. and Cuenin, C. and Abedi-Ardekani, B. and Boland, A. and Olaso, R. and Meyer, V. and Altmuller, J. and Le Calvez-Kelm, F. and Durand, G. and Voegele, C. and Boyault, S. and Moonen, L. and Lemaitre, N. and Lorimier, P. and Toffart, A.C. and Soltermann, A. and Clement, J.H. and Saenger, J. and Field, J.K. and Brevet, M. and Blanc-Fournier, C. and Galateau-Salle, F. and Le Stang, N. and Russell, P.A. and Wright, G. and Sozzi, G. and Pastorino, U. and Lacomme, S. and Vignaud, J.M. and Hofman, V. and Hofman, P. and Brustugun, O.T. and Lund-Iversen, M. and Thomas de Montpreville, V. and Muscarella, L.A. and Graziano, P. and Popper, H. and Stojsic, J. and Deleuze, J.F. and Herceg, Z. and Viari, A. and Nuernberg, P. and Pelosi, G. and Dingemans, A.M.C. and Milione, M. and Roz, L. and Brcic, L. and Volante, M. and Papotti, M.G. and Caux, C. and Sandoval, J. and Hernandez-Vargas, H. and Brambilla, E. and Speel, E.J.M. and Girard, N. and Lantuejoul, S. and McKay, J.D. and Foll, M. and Fernandez-Cuesta, L.
Nature Communications 10
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20 August 2019
Fatty acid-binding protein 4 and risk of type 2 diabetes, myocardial infarction and stroke: a prospective cohort study.
Aleksandrova, K. and Drogan, D. and Weikert, C. and Schulze, M.B. and Fritsche, A. and Boeing, H. and Pischon, T.
Journal of Clinical Endocrinology and Metabolism 104
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December 2019
ACE2 in brain physiology and pathophysiology: evidence from transgenic animal models.
Alenina, N. and Bader, M.
Neurochemical Research 44
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June 2019
Polycystin-1 assembles with Kv channels to govern cardiomyocyte repolarization and contractility.
Altamirano, F. and Schiattarella, G.G. and French, K.M. and Kim, S.Y. and Engelberger, F. and Kyrychenko, S. and Villalobos, E. and Tong, D. and Schneider, J.W. and Ramirez-Sarmiento, C.A. and Lavandero, S. and Gillette, T.G. and Hill, J.A.
Circulation 140
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10 September 2019
Assessment of bones deficient in fibrillin-1 microfibrils reveals pronounced sex differences.
Altinbas, L. and Bormann, N. and Lehmann, D. and Jeuthe, S. and Wulsten, D. and Kornak, U. and Robinson, P.N. and Wildemann, B. and Kararigas, G.
International Journal of Molecular Sciences 20
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1 December 2019
CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing.
Andersch, L. and Radke, J. and Klaus, A. and Schwiebert, S. and Winkler, A. and Schumann, E. and Grunewald, L. and Zirngibl, F. and Flemmig, C. and Jensen, M.C. and Rossig, C. and Joussen, A. and Henssen, A. and Eggert, A. and Schulte, J.H. and Künkele, A.
BMC Cancer 19
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9 September 2019
Analysis of NTRK expression in gastric and esophageal adenocarcinoma (AGE) with pan-TRK immunohistochemistry.
Arnold, A. and Daum, S. and von Winterfeld, M. and Berg, E. and Hummel, M. and Horst, D. and Rau, B. and Stein, U. and Treese, C.
Pathology Research and Practice 215
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November 2019
Regulation of influenza a virus mRNA splicing by CLK1.
Artarini, A. and Meyer, M. and Shin, Y.J. and Huber, K. and Hilz, N. and Bracher, F. and Eros, D. and Orfi, L. and Keri, G. and Goedert, S. and Neuenschwander, M. and von Kries, J. and Domovich-Eisenberg, Y. and Dekel, N. and Szabadkai, I. and Lebendiker, M. and Horváth, Z. and Danieli, T. and Livnah, O. and Moncorgé, O. and Frise, R. and Barclay, W. and Meyer, T.F. and Karlas, A.
Antiviral Research 168
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August 2019
Saffron: The golden spice with therapeutic properties on digestive diseases.
Ashktorab, H. and Soleimani, A. and Singh, G. and Amr, A. and Tabtabaei, S. and Latella, G. and Stein, U. and Akhondzadeh, S. and Solanki, N. and Gondré-Lewis, M.C. and Habtezion, A. and Brim, H.
Nutrients 11
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26 April 2019
Vision and vision-related measures in progressive multiple sclerosis.
Backner, Y. and Petrou, P. and Glick-Shames, H. and Raz, N. and Zimmermann, H. and Jost, R. and Scheel, M. and Paul, F. and Karussis, D. and Levin, N.
Frontiers in Neurology 10
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May 2019
hnRNP-K targets open chromatin in mouse embryonic stem cells in concert with multiple regulators.
Bakhmet, E.I. and Nazarov, I.B. and Gazizova, A.R. and Vorobyeva, N.E. and Kuzmin, A.A. and Gordeev, M.N. and Sinenko, S.A. and Aksenov, N. D. and Artamonova, T.O. and Khodorkovskii, M.A. and Alenina, N. and Onichtchouk, D. and Wu, G. and Schöler, H.R. and Tomilin, A.N.
Stem Cells 37
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August 2019
Retinal inner nuclear layer volume reflects inflammatory disease activity in multiple sclerosis; a longitudinal OCT study.
Balk, L.J. and Coric, D. and Knier, B. and Zimmermann, H.G. and Behbehani, R. and Alroughani, R. and Martinez-Lapiscina, E.H. and Brandt, A.U. and Sánchez-Dalmau, B. and Vidal-Jordana, A. and Albrecht, P. and Koska, V. and Havla, J. and Pisa, M. and Nolan, R.C. and Leocani, L. and Paul, F. and Aktas, O. and Montalban, X. and Balcer, L.J. and Villoslada, P. and Outteryck, O. and Korn, T. and Petzold, A.
Multiple Sclerosis Journal Experimental Translational and Clinical 5
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1 July 2019
Common mode of remodeling AAA ATPases p97/CDC48 by their disassembling cofactors ASPL/PUX1.
Banchenko, S. and Arumughan, A. and Petrović, S. and Schwefel, D. and Wanker, E.E. and Roske, Y. and Heinemann, U.
Structure 27
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3 December 2019
Linoleic acid metabolite DiHOME decreases post-ischemic cardiac recovery in murine hearts.
Bannehr, M. and Löhr, L. and Gelep, J. and Haverkamp, W. and Schunck, W.H. and Gollasch, M. and Wutzler, A.
Cardiovascular Toxicology 19
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August 2019
In contrast to Western diet, a plant-based, high-fat, low-sugar diet does not exacerbate retinal endothelial injury in streptozotocin-induced diabetes.
Barakat, A. and Nakao, S. and Zandi, S. and Sun, D. and Schmidt-Ullrich, R. and Hayes, K.C. and Hafezi-Moghadam, A.
FASEB Journal 33
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September 2019
Short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H. and Balogh, A. and Yakoub, M. and Homann, S. and Markó, L. and Höges, S. and Tsvetkov, D. and Krannich, A. and Wundersitz, S. and Avery, E.G. and Haase, N. and Kräker, K. and Hering, L. and Maase, M. and Kusche-Vihrog, K. and Grandoch, M. and Fielitz, J. and Kempa, S. and Gollasch, M. and Zhumadilov, Z. and Kozhakhmetov, S. and Kushugulova, A. and Eckardt, K.U. and Dechend, R. and Rump, L.C. and Forslund, S.K. and Müller, D.N. and Stegbauer, J. and Wilck, N.
Circulation 139
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12 March 2019
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.
Basheer, F. and Giotopoulos, G. and Meduri, E. and Yun, H. and Mazan, M. and Sasca, D. and Gallipoli, P. and Marando, L. and Gozdecka, M. and Asby, R. and Sheppard, O. and Dudek, M. and Bullinger, L. and Döhner, H. and Dillon, R. and Freeman, S. and Ottmann, O. and Burnett, A. and Russell, N. and Papaemmanuil, E. and Hills, R. and Campbell, P. and Vassiliou, G.S.. and Huntly, B.J.P.
Journal of Experimental Medicine 216
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1 April 2019
Gain-of-function mutations in KCNN3 encoding the small-conductance Ca(2+)-activated K(+) channel SK3 cause Zimmermann-Laband syndrome.
Bauer, C.K. and Schneeberger, P.E. and Kortüm, F. and Altmüller, J. and Santos-Simarro, F. and Baker, L. and Keller-Ramey, J. and White, S.M. and Campeau, P.M. and Gripp, K.W. and Kutsche, K.
American Journal of Human Genetics 104
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6 June 2019
Analysis of correlation-based biomolecular networks from different omics data by fitting stochastic block models.
Baum, K. and Rajapakse, J.C. and Azuaje, F.
F1000Research 8
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27 August 2019
Of gene expression and cell division time: a mathematical framework for advanced differential gene expression and data analysis.
Baum, K. and Schuchhardt, J. and Wolf, J. and Busse, D.
Cell Systems 9
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18 December 2019
Association between physical activity and risk of hepatobiliary cancers: a multinational cohort study.
Baumeister, S.E. and Schlesinger, S. and Aleksandrova, K. and Jochem, C. and Jenab, M. and Gunter, M.J. and Overvad, K. and Tjønneland, A. and Boutron-Ruault, M.C. and Carbonnel, F. and Fournier, A. and Kühn, T. and Kaaks, R. and Pischon, T. and Boeing, H. and Trichopoulou, A. and Bamia, C. and La Vecchia, C. and Masala, G. and Panico, S. and Fasanelli, F. and Tumino, R. and Grioni, S. and de Mesquita, B.B. and Vermeulen, R. and May, A.M. and Borch, K.B. and Oyeyemi, S.O. and Ardanaz, E. and Rodríguez-Barranco, M. and López, M.D.C. and Felez-Nobrega, M. and Sonestedt, E. and Ohlsson, B. and Hemmingsson, O. and Werner, M. and Perez-Cornago, A. and Ferrari, P. and Stepien, M. and Freisling, H. and Tsilidis, K.K. and Ward, H. and Riboli, E. and Weiderpass, E. and Leitzmann, M.F.
Journal of Hepatology 70
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May 2019
Simultaneous high-resolution cardiac T(1) mapping and cine imaging using model-based iterative image reconstruction.
Becker, K.M. and Schulz-Menger, J. and Schaeffter, T. and Kolbitsch, C.
Magnetic Resonance in Medicine 81
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February 2019
Controlling nuclear NF-κB dynamics by β-TrCP-insights from a computational model.
Benary, U. and Wolf, J.
Biomedicines 7
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27 May 2019
Modelling the DNA topology: the effect of the loop bending on G-quadruplex stability.
Bergues-Pupo, A.E. and Falo, F. and Fiasconaro, A.
Journal of Statistical Mechanics: Theory and Experiment 2019
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2 September 2019
Tight junction proteins at the blood-brain barrier: far more than claudin-5.
Berndt, P. and Winkler, L. and Cording, J. and Breitkreuz-Korff, O. and Rex, A. and Dithmer, S. and Rausch, V. and Blasig, R. and Richter, M. and Sporbert, A. and Wolburg, H. and Blasig, I.E. and Haseloff, R.F.
Cellular and Molecular Life Sciences 76
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May 2019
Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy.
Bhaskara, R.M. and Grumati, P. and Garcia-Pardo, J. and Kalayil, S. and Covarrubias-Pinto, A. and Chen, W. and Kudryashev, M. and Dikic, I. and Hummer, G.
Nature Communications 10
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30 May 2019
Modeling single-molecule conformations of the HoxD region in mouse embryonic stem and cortical neuronal cells.
Bianco, S. and Annunziatella, C. and Andrey, G. and Chiariello, A.M. and Esposito, A. and Fiorillo, L. and Prisco, A. and Conte, M. and Campanile, R. and Nicodemi, M.
Cell Reports 28
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6 August 2019
Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger, K.J. and Neukam, M. and Tattikota, S.G. and Qadri, F. and Puchkov, D. and Willmes, D.M. and Wurmsee, S. and Geisberger, S. and Dechend, R. and Raile, K. and Kurth, T. and Nguyen, G. and Poy, M.N. and Solimena, M. and Muller, D.N. and Birkenfeld, A.L.
Proceedings of the National Academy of Sciences of the United States of America 116
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1 October 2019
Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein.
Birol, M. and Wojcik, S.P. and Miranker, A.D. and Rhoades, E.
PLoS Biology 17
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18 June 2019
Aldosterone, salt, and potassium intakes as predictors of pregnancy outcome, including preeclampsia.
Birukov, A. and Andersen, L.B. and Herse, F. and Rakova, N. and Kitlen, G. and Kyhl, H.B. and Golic, M. and Haase, N. and Kräker, K. and Müller, D.N. and Jørgensen, J.S. and Andersen, M.S. and Dechend, R. and Jensen, B.L.
Hypertension 74
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August 2019
Regulatory antibodies against GPCR in women ten years after early-onset preeclampsia.
Birukov, A. and Muijsers, H.E.C. and Heidecke, H. and Drost, J.T. and Cunnigham, M.W. and Kraker, K. and Haase, N. and Frolova, A. and Müller, D.N. and Herse, F. and Maas, A.H.E.M. and Dechend, R.
Frontiers in Bioscience 24
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1 June 2019
A clonal expression biomarker associates with lung cancer mortality.
Biswas, D. and Birkbak, N.J. and Rosenthal, R. and Hiley, C.T. and Lim, E.L. and Papp, K. and Boeing, S. and Krzystanek, M. and Djureinovic, D. and La Fleur, L. and Greco, M. and Döme, B. and Fillinger, J. and Brunnström, H. and Wu, Y. and Moore, D.A. and Skrzypski, M. and Abbosh, C. and Litchfield, K. and Al Bakir, M. and Watkins, T.B.K. and Veeriah, S. and Wilson, G.A. and Jamal-Hanjani, M. and Moldvay, J. and Botling, J. and Chinnaiyan, A.M. and Micke, P. and Hackshaw, A. and Bartek, J. and Csabai, I. and Szallasi, Z. and Herrero, J. and McGranahan, N. and Swanton, C.
Nature Medicine 25
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October 2019
Diagnostik und Therapie von Tuberkulose unter Immuntherapien für Multiple Sklerose : aktueller Stand und Empfehlungen in Deutschland [Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : current status and recommendations in Germany].
Bittner, S. and Engel, S. and Lange, C. and Weber, M.S. and Haghikia, A. and Luessi, F. and Korn, T. and Klotz, L. and Bayas, A. and Paul, F. and Heesen, C. and Stangel, M. and Wildemann, B. and Bergh, F.T. and Tackenberg, B. and Trebst, C. and Warnke, C. and Linker, R. and Kerschensteiner, M. and Zettl, U. and Tumani, H. and Brück, W. and Meuth, S.G. and Kümpfel, T. and Hemmer, B. and Wiendl, H. and Gold, R. and Zipp, F.
Nervenarzt 90
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December 2019
Identification and ranking of recurrent neo-epitopes in cancer.
Blanc, E. and Holtgrewe, M. and Dhamodaran, A. and Messerschmidt, C. and Willimsky, G. and Blankenstein, T. and Beule, D.
BMC Medical Genomics 12
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27 November 2019
Subclinical myocardial injury in patients with Facioscapulohumeral muscular dystrophy 1 and preserved ejection fraction - assessment by cardiovascular magnetic resonance.
Blaszczyk, E. and Grieben, U. and von Knobelsdorff-Brenkenhoff, F. and Kellman, P. and Schmacht, L. and Funk, S. and Spuler, S. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 21
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29 April 2019
Chiral lipidomics of monoepoxy and monohydroxy metabolites derived from long-chain polyunsaturated fatty acids.
Blum, M. and Dogan, I. and Karber, M. and Rothe, M. and Schunck, W.H.
Journal of Lipid Research 60
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January 2019
Identification and regulation of the long non-coding RNA Heat2 in heart failure.
Boeckel, J.N. and Perret, M.F. and Glaser, S.F. and Seeger, T. and Heumüller, A.W. and Chen, W. and John, D. and Kokot, K.E. and Katus, H.A. and Haas, J. and Lackner, M.K. and Kayvanpour, E. and Grabe, N. and Dieterich, C. and von Haehling, S. and Ebner, N. and Hünecke, S. and Leuschner, F. and Fichtlscherer, S. and Meder, B. and Zeiher, A.M. and Dimmeler, S. and Keller, T.
Journal of Molecular and Cellular Cardiology 126
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January 2019
The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A. and Babila, J.T. and Wiglenda, T. and Diez, L. and Jacob, M. and Nietfeld, W. and Huska, M.R. and Haenig, C. and Groenke, N. and Buntru, A. and Blanc, E. and Meier, J.C. and Vannoni, E. and Erck, C. and Friedrich, B. and Martens, H. and Neuendorf, N. and Schnoegl, S. and Wolfer, D.P. and Loos, M. and Beule, D. and Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 26
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17 January 2019
Cardiorenal sodium MRI at 7.0 Tesla using a 4/4 channel (1)H/(23)Na radiofrequency antenna array.
Boehmert, L. and Kuehne, A. and Waiczies, H. and Wenz, D. and Eigentler, T.W. and Funk, S. and von Knobelsdorff-Brenkenhoff, F. and Schulz-Menger, J. and Nagel, A.M. and Seeliger, E. and Niendorf, T.
Magnetic Resonance in Medicine 82
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December 2019
The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B. and Wang, X. and Eichelbaum, K. and Sadewasser, A. and Husic, I. and Paki, K. and Budt, M. and Hergeselle, M. and Vetter, B. and Hou, J. and Chen, W. and Wiebusch, L. and Meyer, I.M. and Wolff, T. and Selbach, M.
Nature Communications 10
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4 December 2019
New targeted agents in acute myeloid leukemia: new hope on the rise.
Bohl, S.R. and Bullinger, L. and Rücker, F.G.
International Journal of Molecular Sciences 20
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23 April 2019
Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage.
Boltze, J. and Ferrara, F. and Hainsworth, A.H. and Bridges, L.R. and Zille, M. and Lobsien, D. and Barthel, H. and McLeod, D.D. and Gräßer, F. and Pietsch, S. and Schatzl, A.K. and Dreyer, A.Y. and Nitzsche, B.
Journal of Cerebral Blood Flow and Metabolism 39
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1 December 2019
WiPP: workflow for improved peak picking for gas chromatography-mass spectrometry (GC-MS) data.
Borgsmüller, N. and Gloaguen, Y. and Opialla, T. and Blanc, E. and Sicard, E. and Royer, A.L. and Le Bizec, B. and Durand, S. and Migné, C. and Pétéra, M. and Pujos-Guillot, E. and Giacomoni, F. and Guitton, Y. and Beule, D. and Kirwan, J.
Metabolites 9
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21 August 2019
Somatostatin 2 receptors in the spinal cord tonically restrain thermogenic, cardiac and other sympathetic outflows.
Bowman, B.R. and Bokiniec, P. and McMullan, S. and Goodchild, A.K. and Burke, P.G.R.
Frontiers in Neuroscience 13
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February 2019
EU-OPENSCREEN: a novel collaborative approach to facilitate chemical biology.
Brennecke, P. and Rasina, D. and Aubi, O. and Herzog, K. and Landskron, J. and Cautain, B. and Vicente, F. and Quintana, J. and Mestres, J. and Stechmann, B. and Ellinger, B. and Brea, J. and Kolanowski, J.L. and Pilarski, R. and Orzaez, M. and Pineda-Lucena, A. and Laraia, L. and Nami, F. and Zielenkiewicz, P. and Paruch, K. and Hansen, E. and von Kries, J.P. and Neuenschwander, M. and Specker, E. and Bartunek, P. and Simova, S. and Leśnikowski, Z. and Krauss, S. and Lehtiö, L. and Bilitewski, U. and Brönstrup, M. and Taskén, K. and Jirgensons, A. and Lickert, H. and Clausen, M.H. and Andersen, J.H. and Vicent, M.J. and Genilloud, O. and Martinez, A. and Nazaré, M. and Fecke, W. and Gribbon, P.
SLAS Discovery 24
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1 March 2019
RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses.
Brockmann, M.M. and Maglione, M. and Willmes, C.G. and Stumpf, A. and Bouazza, B.A. and Velasquez, L.M. and Grauel, M.K. and Beed, P. and Lehmann, M. and Gimber, N. and Schmoranzer, J. and Sigrist, S.J. and Rosenmund, C. and Schmitz, D.
eLife 8
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19 September 2019
Time-resolved DNA release from an O-antigen specific Salmonella bacteriophage with a contractile tail.
Broeker, N.K. and Roske, Y. and Valleriani, A. and Stephan, M.S. and Andres, D. and Koetz, J. and Heinemann, U. and Barbirz, S.
Journal of Biological Chemistry 294
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Nature Immunology 20
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May 2019
Cluster binding studies with two anti-Thomsen-Friedenreich (anti-core-1, CD176, TF) antibodies: evidence for a multiple TF epitope.
Flechner, A. and Butschak, G. and Löffler, A. and Rühmann, J. and Nishimura, S.I. and Dölling, R. and Purfürst, B. and Goletz, S. and Danielczyk, A. and Karsten, U.
International Immunopharmacology 72
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July 2019
The transcription factor Hey and nuclear lamins specify and maintain cell identity.
Flint Brodsly, N. and Bitman-Lotan, E. and Boico, O. and Shafat, A. and Monastirioti, M. and Gessler, M. and Delidakis, C. and Rincon-Arano, H. and Orian, A.
eLife 8
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16 July 2019
Unstable TTTTA/TTTCA expansions in MARCH6 are associated with Familial Adult Myoclonic Epilepsy type 3.
Florian, R.T. and Kraft, F. and Leitão, E. and Kaya, S. and Klebe, S. and Magnin, E. and van Rootselaar, A.F. and Buratti, J. and Kühnel, T. and Schröder, C. and Giesselmann, S. and Tschernoster, N. and Altmüller, J. and Lamiral, A. and Keren, B. and Nava, C. and Bouteiller, D. and Forlani, S. and Jornea, L. and Kubica, R. and Ye, T. and Plassard, D. and Jost, B. and Meyer, V. and Deleuze, J.F. and Delpu, Y. and Avarello, M.D.M. and Vijfhuizen, L.S. and Rudolf, G. and Hirsch, E. and Kroes, T. and Reif, P.S. and Rosenow, F. and Ganos, C. and Vidailhet, M. and Thivard, L. and Mathieu, A. and Bourgeron, T. and Kurth, I. and Rafehi, H. and Steenpass, L. and Horsthemke, B. and LeGuern, E. and Klein, K.M. and Labauge, P. and Bennett, M.F. and Bahlo, M. and Gecz, J. and Corbett, M.A. and Tijssen, M.A.J and van den Maagdenberg, A.M.J.M. and Depienne, C.
Nature Communications 10
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29 October 2019
Evolution of protein domain architectures.
Forslund, S.K. and Kaduk, M. and Sonnhammer, E.L.L.
Methods in Molecular Biology 1910
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2019
The role of receptor MAS in microglia-driven retinal vascular development.
Foulquier, S. and Caolo, V. and Swennen, G. and Milanova, I. and Reinhold, S. and Recarti, C. and Alenina, N. and Bader, M. and Steckelings, U M. and Vanmierlo, T. and Post, M.J. and Jones, E.A. and van Oostenbrugge, R.J. and Unger, T.
Angiogenesis 22
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November 2019
Circular RNAs in clear cell renal cell carcinoma: their microarray-based identification, analytical validation, and potential use in a clinico-genomic model to improve prognostic accuracy.
Franz, A. and Ralla, B. and Weickmann, S. and Jung, M. and Rochow, H. and Stephan, C. and Erbersdobler, A. and Kilic, E. and Fendler, A. and Jung, K.
Cancers 11
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30 September 2019
Specific chromatin changes mark lateral organ founder cells in the Arabidopsis inflorescence meristem.
Frerichs, A. and Engelhorn, J. and Altmüller, J. and Gutierrez-Marcos, J. and Werr, W.
Journal of Experimental Botany 70
(15): 3867-3879.
1 August 2019
Role of donor clonal hematopoiesis in allogeneic hematopoietic stem-cell transplantation.
Frick, M. and Chan, W. and Arends, C.M. and Hablesreiter, R. and Halik, A. and Heuser, M. and Michonneau, D. and Blau, O. and Hoyer, K. and Christen, F. and Galan-Sousa, J. and Noerenberg, D. and Wais, V. and Stadler, M. and Yoshida, K. and Schetelig, J. and Schuler, E. and Thol, F. and Clappier, E. and Christopeit, M. and Ayuk, F. and Bornhäuser, M. and Blau, I.W. and Ogawa, S. and Zemojtel, T. and Gerbitz, A. and Wagner, E.M. and Spriewald, B.M. and Schrezenmeier, H. and Kuchenbauer, F. and Kobbe, G. and Wiesneth, M. and Koldehoff, M. and Socié, G. and Kroeger, N. and Bullinger, L. and Thiede, C. and Damm, F.
Journal of Clinical Oncology 37
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10 February 2019
Protease-activated receptor 2 deficiency mediates cardiac fibrosis and diastolic dysfunction.
Friebel, J. and Weithauser, A. and Witkowski, M. and Rauch, B.H. and Savvatis, K. and Dörner, A. and Tabaraie, T. and Kasner, M. and Moos, V. and Bösel, D. and Gotthardt, M. and Radke, M.H. and Wegner, M. and Bobbert, P. and Lassner, D. and Tschöpe, C. and Schutheiss, H.P. and Felix, S.B. and Landmesser, U. and Rauch, U.
European Heart Journal 40
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21 October 2019
Stochastic transcription in the p53-mediated response to DNA damage is modulated by burst frequency.
Friedrich, D. and Friedel, L. and Finzel, A. and Herrmann, A. and Preibisch, S. and Loewer, A.
Molecular Systems Biology 15
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1 December 2019
Modified protocol of harvesting, extraction, and normalization approaches for gas chromatography mass spectrometry-based metabolomics analysis of adherent cells grown under high fetal calf serum conditions.
Fritsche-Guenther, R. and Bauer, A. and Gloaguen, Y. and Lorenz, M. and Kirwan, J.A.
Metabolites 10
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18 December 2019
Metabolic modulation regulates cardiac wall morphogenesis in zebrafish.
Fukuda, R. and Aharonov, A. and Ong, Y.T. and Stone, O.A. and El-Brolosy, M. and Maischein, H.M. and Potente, M. and Tzahor, El. and Stainier, D.Y.R.
eLife 8
23 December 2019
The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.
Funk, N. and Munz, M. and Ott, T. and Brockmann, K. and Wenninger-Weinzierl, A. and Kühn, R. and Vogt-Weisenhorn, D. and Giesert, F. and Wurst, W. and Gasser, T. and Biskup, S.
Scientific Reports 9
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14 March 2019
A benchmark for epithelial cell tracking.
Funke, J. and Mais, L. and Champion, A. and Dye, N. and Kainmueller, D.
Lecture Notes in Computer Science 11134
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23 January 2019
Supramolecular nanogels fabricated via host-guest molecular recognition as penetration enhancer for dermal drug delivery.
Gao, L. and Zabihi, F. and Ehrmann, S. and Hedtrich, S. and Haag, R.
Journal of Controlled Release 300
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28 April 2019
Caloric restriction induces H(2)O(2) formation as a trigger of AMPK-eNOS-NO pathway in obese rats: role for CAMKII.
García-Prieto, C.F. and Gil-Ortega, M. and Plaza, A. and Manzano-Lista, F.J. and González-Blázquez, R. and Alcalá, M. and Rodríguez-Rodríguez, P. and Viana, M. and Aranguez, I. and Gollasch, M. and Somoza, B. and Fernández-Alfonso, M.S.
Free Radical Biology and Medicine 139
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1 August 2019
Association of intrathecal immunoglobulin G synthesis with disability worsening in multiple sclerosis.
Gasperi, C. and Salmen, A. and Antony, G. and Bayas, A. and Heesen, C. and Kümpfel, T. and Linker, R.A. and Paul, F. and Stangel, M. and Tackenberg, B. and Bergh, F.T. and Warnke, C. and Weber, F. and Wiendl, H. and Wildemann, B. and Zettl, U.K. and Ziemann, U. and Zipp, F. and Tumani, H. and Gold, R. and Hemmer, B.
JAMA Neurology 76
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29 April 2019
Von konditionierten Ratten und gestressten Werktätigen: Rudolf Baumann und der Stress- und Umweltdiskurs in der DDR [On conditioned rats and stressed workmen: Rudolf Baumann and the discourse about stress and environment in the GDR].
Gausemeier, B.
NTM Zeitschrift für Geschichte der Wissenschaften, Technik und Medizin 27
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September 2019
The danger signal extracellular ATP is involved in the immunomediated damage of α-sarcoglycan-deficient muscular dystrophy.
Gazzerro, E. and Baratto, S. and Assereto, S. and Baldassari, S. and Panicucci, C. and Raffaghello, L. and Scudieri, P. and De Battista, D. and Fiorillo, C. and Volpi, S. and Chaabane, L. and Malnati, M. and Messina, G. and Bruzzone, S. and Traggiai, E. and Grassi, F. and Minetti, C. and Bruno, C.
American Journal of Pathology 189
(2): 354-369.
February 2019
Priming of LTP in amygdala and hippocampus by prior paired pulse facilitation paradigm in mice lacking brain serotonin.
Gebhardt, C. and Mosienko, V. and Alenina, N. and Albrecht, D.
Hippocampus 29
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July 2019
Olfactory and gustatory dysfunction in patients with autoimmune encephalitis.
Geran, R. and Uecker, F.C. and Prüss, H. and Haeusler, K.G. and Paul, F. and Ruprecht, K. and Harms, L. and Schmidt, F.A.
Frontiers in Neurology 10
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May 2019
Artery-vein specification in the zebrafish trunk is pre-patterned by heterogeneous Notch activity and balanced by flow-mediated fine tuning.
Geudens, I. and Coxam, B. and Alt, S. and Gebala, V. and Vion, A.C. and Meier, K. and Rosa, A. and Gerhardt, H.
Development 146
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27 August 2019
Maximal exercise and plasma cytochrome P450 and lipoxygenase mediators: a lipidomics study.
Gollasch, B. and Dogan, I. and Rothe, M. and Gollasch, M. and Luft, F.C.
Physiological Reports 7
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August 2019
Maximal exercise and erythrocyte fatty-acid status: a lipidomics study.
Gollasch, B. and Dogan, I. and Rothe, M. and Gollasch, M. and Luft, F.C.
Physiological Reports 7
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April 2019
Maximal exercise and erythrocyte epoxy fatty acids: a lipidomics study.
Gollasch, B. and Wu, G. and Dogan, I. and Rothe, M. and Gollasch, M. and Luft, F.C.
Physiological Reports 7
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November 2019
Evaluation des Medizinischen Praktischen Jahres (PJ) an der Charité - Universitätsmedizin Berlin [Project Report: Evaluation of the Practical Year (PY) at the Charité Medical School, University Medicine Berlin].
Gollasch, M. and Kube, P. and Danz, B. and Arens, S. and Märdian, S.
Zeitschrift fuer Evidenz, Fortbildung und Qualitaet im Gesundheitswesen 141-142
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May 2019
HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M. and Yu, Y. and Liang, L. and Vuralli, D. and Froehler, S. and Kuehnen, P. and Du Bois, P. and Zhang, J. and Cao, A. and Liu, Y. and Hussain, K. and Fielitz, J. and Jia, S. and Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7
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May 2019
Lung purinoceptor activation triggers ventilator-induced brain injury.
González-López, A. and López-Alonso, I. and Pickerodt, P.A. and von Haefen, C. and Amado-Rodríguez, L. and Reimann, H. and Niendorf, T. and Kuebler, W. and Albaiceta, G.M. and Francis, R.C.E. and Spies, C.D.
Critical Care Medicine 47
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November 2019
An N-ethyl-N-nitrosourea (ENU)-induced Tyr265Stop mutation of the DNA polymerase accessory subunit gamma 2 (Polg2) is associated with renal calcification in mice.
Gorvin, C.M. and Ahmad, B.N. and Stechman, M.J. and Loh, N.Y. and Hough, T.A. and Leo, P. and Marshall, M. and Sethi, S. and Bentley, L. and Piret, S.E. and Reed, A. and Jeyabalan, J. and Christie, P.T. and Wells, S. and Simon, M.M. and Mallon, A.M. and Schulz, H. and Huebner, N. and Brown, M.A. and Cox, R.D. and Brown, S.D. and Thakker, R.V.
Journal of Bone and Mineral Research 34
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March 2019
Mice with a Brd4 mutation represent a new model of nephrocalcinosis.
Gorvin, C.M. and Loh, N.Y. and Stechman, M.J. and Falcone, S. and Hannan, F.M. and Ahmad, B.N. and Piret, S.E. and Reed, A.A.C. and Jeyabalan, J. and Leo, P. and Marshall, M. and Sethi, S. and Bass, P. and Roberts, I. and Sanderson, J. and Wells, S. and Hough, T.A. and Bentley, L. and Christie, P.T. and Simon, M.M. and Mallon, A.M. and Schulz, H. and Cox, R.D. and Brown, M.A. and Huebner, N. and Brown, S.D. and Thakker, R.V.
Journal of Bone and Mineral Research 34
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July 2019
Ice-age climate adaptations trap the alpine marmot in a state of low genetic diversity.
Gossmann, T.I. and Shanmugasundram, A. and Börno, S. and Duvaux, L. and Lemaire, C. and Kuhl, H. and Klages, S. and Roberts, L.D. and Schade, S. and Gostner, J.M. and Hildebrand, F. and Vowinckel, J. and Bichet, C. and Mülleder, M. and Calvani, E. and Zelezniak, A. and Griffin, J.L. and Bork, P. and Allaine, D. and Cohas, A. and Welch, J.J. and Timmermann, B. and Ralser, M.
Current Biology 29
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20 May 2019
Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis.
Graetz, C. and Gröger, A. and Luessi, F. and Salmen, A. and Zöller, D. and Schultz, J. and Siller, N. and Fleischer, V. and Bellenberg, B. and Berthele, A. and Biberacher, V. and Havla, J. and Hecker, M. and Hohlfeld, R. and Infante-Duarte, C. and Kirschke, J.S. and Kümpfel, T. and Linker, R. and Paul, F. and Pfeuffer, S. and Sämann, P. and Toenges, G. and Weber, F. and Zettl, U.K. and Jahn-Eimermacher, A. and Antony, G. and Groppa, S. and Wiendl, H. and Hemmer, B. and Mühlau, M. and Lukas, C. and Gold, R. and Lill, C.M. and Zipp, F.
Multiple Sclerosis Journal 25
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1 April 2019
sgRNA sequence motifs blocking efficient CRISPR/Cas9-mediated gene editing.
Graf, R. and Li, X. and Chu, V.T. and Rajewsky, K.
Cell Reports 26
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29 January 2019
BCR-dependent lineage plasticity in mature B cells.
Graf, R. and Seagal, J. and Otipoby, K.L. and Lam, K.P. and Ayoub, S. and Zhang, B. and Sander, S. and Chu, V.T. and Rajewsky, K.
Science 363
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15 February 2019
Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk.
Greenwald, W.W. and Chiou, J. and Yan, J. and Qiu, Y. and Dai, N. and Wang, A. and Nariai, N. and Aylward, A. and Han, J.Y. and Kadakia, N. and Regue, L. and Okino, M.L. and Drees, F. and Kramer, D. and Vinckier, N. and Minichiello, L. and Gorkin, D. and Avruch, J. and Frazer, K.A. and Sander, M. and Ren, B. and Gaulton, K.J.
Nature Communications 10
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7 May 2019
Combined targeted resequencing of cytosine DNA methylation and mutations of DNA repair genes with potential use for poly(ADP-ribose) polymerase 1 inhibitor sensitivity testing.
Grimm, C. and Fischer, A. and Farrelly, A.M. and Kalachand, R. and Castiglione, R. and Wasserburger, E. and Hussong, M. and Schultheis, Anne M and Altmüller, J. and Thiele, H. and Reinhardt, H.C. and Hauschulz, K. and Hennessy, B.T. and Herwig, R. and Lienhard, M. and Buettner, R. and Schweiger, M.R.
Journal of Molecular Diagnostics 21
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March 2019
CD8(+) T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.
Gross, C.C. and Meyer, C. and Bhatia, U. and Yshii, L. and Kleffner, I. and Bauer, J. and Tröscher, A.R. and Schulte-Mecklenbeck, A. and Herich, S. and Schneider-Hohendorf, T. and Plate, H. and Kuhlmann, T. and Schwaninger, M. and Brück, W. and Pawlitzki, M. and Laplaud, D.A. and Loussouarn, D. and Parratt, J. and Barnett, M. and Buckland, M.E. and Hardy, T.A. and Reddel, S.W. and Ringelstein, M. and Dörr, J. and Wildemann, B. and Kraemer, M. and Lassmann, H. and Höftberger, R. and Beltrán, E. and Dornmair, K. and Schwab, N. and Klotz, L. and Meuth, S.G. and Martin-Blondel, G. and Wiendl, H. and Liblau, R.
Nature Communications 10
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18 December 2019
TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation.
Grund, A. and Szaroszyk, M. and Korf-Klingebiel, M. and Malek Mohammadi, M. and Trogisch, F.A. and Schrameck, U. and Gigina, A. and Tiedje, C. and Gaestel, M. and Kraft, T. and Hegermann, J. and Batkai, S. and Thum, T. and Perrot, A. and Remedios, C.D. and Riechert, E. and Völkers, M. and Doroudgar, S. and Jungmann, A. and Bauer, R. and Yin, X. and Mayr, M. and Wollert, K.C. and Pich, A. and Xiao, H. and Katus, H.A. and Bauersachs, J. and Müller, O.J. and Heineke, J.
EMBO Molecular Medicine 11
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1 October 2019
Accurate assessment of LV function using the first automated 2D-border detection algorithm for small animals - evaluation and application to models of LV dysfunction.
Grune, J. and Ritter, D. and Kräker, K. and Pappritz, K. and Beyhoff, N. and Schütte, T. and Ott, C. and John, C. and van Linthout, S. and Tschöpe, C. and Dechend, R. and Muller, D.N. and Haase, N. and Grune, T. and Kintscher, U. and Kuebler, W.M.
Cardiovascular Ultrasound 17
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22 April 2019
Altered microRNA and target gene expression related to tetralogy of fallot.
Grunert, M. and Appelt, S. and Dunkel, I. and Berger, F. and Sperling, S.R.
Scientific Reports 9
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13 December 2019
Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement.
Grushevskyi, E.O. and Kukaj, T. and Schmauder, R. and Bock, A. and Zabel, U. and Schwabe, T. and Benndorf, K. and Lohse, M.J.
Proceedings of the National Academy of Sciences of the United States of America 116
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14 May 2019
Serine protease mauritanicain from euphorbia mauritanica and phorbol-12-myristate-13-acetate modulate the IL-8 release in fibroblasts and HaCaT keratinocytes.
Guenther, F. and Maus, D. and Hedtrich, S. and Melzig, M.F.
Planta Medica 85
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May 2019
Interactions between carboxypeptidase M and kinin B1 receptor in endothelial cells.
Guimarães, P.B. and da Silva, R.F. and Hoff, C.C. and Fernandes, L. and Nakaie, C.R. and Chagas, J.R. and Karaoglanovic Carmona, A. and Bader, M. and Pesquero, J.B.
Inflammation Research 68
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October 2019
Brain maturation is associated with increasing tissue stiffness and decreasing tissue fluidity.
Guo, J. and Bertalan, G. and Meierhofer, D. and Klein, C. and Schreyer, S. and Steiner, B. and Wang, S. and Vieira da Silva, R. and Infante-Duarte, C. and Koch, S. and Boehm-Sturm, P. and Braun, J. and Sack, I.
Acta Biomaterialia 99
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November 2019
Quantitative proteome landscape of the NCI-60 cancer cell lines.
Guo, T. and Luna, A. and Rajapakse, V.N. and Koh, C.C. and Wu, Z. and Liu, W. and Sun, Y. and Gao, H. and Menden, M.P. and Xu, C. and Calzone, L. and Martignetti, L. and Auwerx, C. and Buljan, M. and Banaei-Esfahani, A. and Ori, A. and Iskar, M. and Gillet, L. and Bi, R. and Zhang, J. and Zhang, H. and Yu, C. and Zhong, Q. and Varma, S. and Schmitt, U. and Qiu, P. and Zhang, Q. and Zhu, Y. and Wild, P.J. and Garnett, M.J. and Bork, P. and Beck, M. and Liu, K. and Saez-Rodriguez, J. and Elloumi, F. and Reinhold, W.C. and Sander, C. and Pommier, Y. and Aebersold, R.
iScience 21
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31 October 2019
Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism.
Göppner, C. and Orozco, I.J. and Hoegg-Beiler, M.B. and Soria, A.H. and Hübner, C.A. and Fernandes-Rosa, F.L. and Boulkroun, S. and Zennaro, M.C. and Jentsch, T.J.
Nature Communications 10
(1): 4678.
15 October 2019
Tenascin C regulates multiple microglial functions involving TLR4 signaling and HDAC1.
Haage, V. and Elmadany, N. and Roll, L. and Faissner, A. and Gutmann, D.H. and Semtner, M. and Kettenmann, H.
Brain Behavior and Immunity 81
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October 2019
Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma.
Haage, V. and Semtner, M. and Oliveira Vidal, R. and Perez Hernandez, D. and Pong, W.W. and Chen, Z. and Hambardzumyan, D. and Magrini, V. and Ly, A. and Walker, J. and Mardis, E. and Mertins, P. and Sauer, S. and Kettenmann, H. and Gutmann, D.H.
Acta Neuropathologica Communications 7
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14 February 2019
Circulating MACC1 transcripts in glioblastoma patients predict prognosis and treatment response.
Hagemann, C. and Neuhaus, N. and Dahlmann, M. and Kessler, A.F. and Kobelt, D. and Herrmann, P. and Eyrich, M. and Freitag, B. and Linsenmann, T. and Monoranu, C.M. and Ernestus, R.I. and Löhr, M. and Stein, U.
Cancers 11
(6): 825.
13 June 2019
MRG-1/MRG15 is a barrier for germ cell to neuron reprogramming in Caenorhabditis elegans.
Hajduskova, M. and Baytek, G. and Kolundzic, E. and Gosdschan, A. and Kazmierczak, M. and Ofenbauer, A. and Beato del Rosal, M.L. and Herzog, S. and ul Fatima, N. and Mertins, P. and Seelk-Müthel, S. and Tursun, B.
Genetics 211
(1): 121-139.
1 January 2019
3D high resolution imaging of human heart for visualization of the cardiac structure.
Haliot, K. and Magat, J. and Ozenne, V. and Abell, E. and Dubes, V. and Bear, L. and Gilbert, S.H. and Trew, M.L. and Haissaguerre, M. and Quesson, B. and Bernus, O.
Lecture Notes in Computer Science 11504
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30 May 2019
Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.
Han, Y. and Lindner, S. and Bei, Y. and Garcia, H.D. and Timme, N. and Althoff, K. and Odersky, A. and Schramm, A. and Lissat, A. and Künkele, A. and Deubzer, H.E. and Eggert, A. and Schulte, J.H. and Henssen, A.G.
Cancer Letters 445
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31 March 2019
The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons.
Handara, G. and Hetsch, F.J.A. and Jüttner, R. and Schick, A. and Haupt, C. and Rathjen, F.G. and Kröger, S.
Developmental Biology 445
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1 January 2019
GOPHER: Generator Of Probes for capture Hi-C Experiments at high Resolution.
Hansen, P. and Ali, S. and Blau, H. and Danis, D. and Hecht, J. and Kornak, U. and Lupiáñez, D.G. and Mundlos, S. and Steinhaus, R. and Robinson, P.N.
BMC Genomics 20
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14 January 2019
Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment.
Haremaki, T. and Metzger, J.J. and Rito, T. and Ozair, M.Z. and Etoc, F. and Brivanlou, A.H.
Nature Biotechnology 37
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October 2019
Parallel generation of easily selectable multiple nephronal cell types from human pluripotent stem cells.
Hariharan, K. and Stachelscheid, H. and Rossbach, B. and Oh, S.J. and Mah, N. and Schmidt-Ott, K. and Kurtz, A. and Reinke, P.
Cellular and Molecular Life Sciences 76
(1): 179-192.
January 2019
R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.
Harnack, C. and Berger, H. and Antanaviciute, A. and Vidal, R. and Sauer, S. and Simmons, A. and Meyer, T.F. and Sigal, M.
Nature Communications 10
(1): 4368.
25 September 2019
Escalation of memory length in finite populations.
Harrington, K. and Pollack, J.
Artificial Life 25
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2 April 2019
Mesothelial cell HIF1α expression is metabolically downregulated by metformin to prevent oncogenic tumor-stromal crosstalk.
Hart, P.C. and Kenny, H.A. and Grassl, N. and Watters, K.M. and Litchfield, L.M. and Coscia, F. and Blaženović, I. and Ploetzky, L. and Fiehn, O. and Mann, M. and Lengyel, E. and Romero, I.L.
Cell Reports 29
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17 December 2019
Deleterious somatic variants in 473 consecutive individuals with ovarian cancer: results of the observational AGO-TR1 study (NCT02222883).
Hauke, J. and Hahnen, E. and Schneider, S. and Reuss, A. and Richters, L. and Kommoss, S. and Heimbach, A. and Marmé, F. and Schmidt, S. and Prieske, K. and Gevensleben, H. and Burges, A. and Borde, J. and De Gregorio, N. and Nürnberg, P. and El-Balat, A. and Thiele, H. and Hilpert, F. and Altmüller, J. and Meier, W. and Dietrich, D. and Kimmig, R. and Schoemig-Markiefka, B. and Kast, K. and Braicu, E. and Baumann, K. and Jackisch, C. and Park-Simon, T.W. and Ernst, C. and Hanker, L. and Pfisterer, J. and Schnelzer, A. and du Bois, A. and Schmutzler, R.K. and Harter, P.
Journal of Medical Genetics 56
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September 2019
Multiregion human bladder cancer sequencing reveals tumour evolution, bladder cancer phenotypes and implications for targeted therapy.
Heide, T. and Maurer, A. and Eipel, M. and Knoll, K. and Geelvink, M. and Veeck, J. and Knuechel, R. and van Essen, J. and Stoehr, R. and Hartmann, A. and Altmueller, J. and Graham, T.A. and Gaisa, N.T.
Journal of Pathology 248
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June 2019
E47 modulates hepatic glucocorticoid action.
Hemmer, M.C. and Wierer, M. and Schachtrup, K. and Downes, M. and Hübner, N. and Evans, R.M. and Uhlenhaut, N.H.
Nature Communications 10
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18 January 2019
Endothelial calcineurin signaling restrains metastatic outgrowth by regulating Bmp2.
Hendrikx, S. and Coso, S. and Prat-Luri, B. and Wetterwald, L. and Sabine, A. and Franco, C.A. and Nassiri, S. and Zangger, N. and Gerhardt, H. and Delorenzi, M. and Petrova, T.V.
Cell Reports 26
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29 January 2019
Dietary protein restriction throughout intrauterine and postnatal life results in potentially beneficial myocardial tissue remodeling in the adult mouse heart.
Hennig, M. and Ewering, L. and Pyschny, S. and Shimoyama, S. and Olecka, M. and Ewald, D. and Magarin, M. and Uebing, A. and Thierfelder, L. and Jux, C. and Drenckhahn, J.D.
Scientific Reports 9
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22 October 2019
Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine.
Herberg, M. and Siebert, S. and Quaas, M. and Thalheim, T. and Rother, K. and Hussong, M. and Altmüller, J. and Kerner, C. and Galle, J. and Schweiger, M.R. and Aust, G.
Clinical Epigenetics 11
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27 April 2019
Preclinical evaluation of a cell-based gene therapy using the Sleeping Beauty transposon system in choroidal neovascularization.
Hernandez, M. and Recalde, S. and Garcia-Garcia, L. and Bezunartea, J. and Miskey, C. and Johnen, S. and Diarra, S. and Sebe, A. and Rodriguez-Madoz, J.R. and Pouillot, S. and Marie, C. and Izsvák, Z. and Scherman, D. and Kropp, M. and Prosper, F. and Thumann, G. and Ivics, Z. and Garcia-Layana, A. and Fernandez-Robredo, P.
Molecular Therapy - Methods and Clinical Development 15
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13 December 2019
Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.
Herrlinger, U. and Tzaridis, T. and Mack, F. and Steinbach, J.P. and Schlegel, U. and Sabel, M. and Hau, P. and Kortmann, R.D. and Krex, D. and Grauer, O. and Goldbrunner, R. and Schnell, O. and Bähr, O. and Uhl, M. and Seidel, C. and Tabatabai, G. and Kowalski, T. and Ringel, F. and Schmidt-Graf, F. and Suchorska, B. and Brehmer, S. and Weyerbrock, A. and Renovanz, M. and Bullinger, L. and Galldiks, N. and Vajkoczy, P. and Misch, M. and Vatter, H. and Stuplich, M. and Schäfer, N. and Kebir, S. and Weller, J. and Schaub, C. and Stummer, W. and Tonn, J.C. and Simon, M. and Keil, V.C. and Nelles, M. and Urbach, H. and Coenen, M. and Wick, W. and Weller, M. and Fimmers, R. and Schmid, M. and Hattingen, E. and Pietsch, T. and Coch, C. and Glas, M.
Lancet 393
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16 February 2019
A C/EBPα-Wnt connection in gut homeostasis and carcinogenesis.
Heuberger, J. and Hill, U. and Förster, S. and Zimmermann, K. and Malchin, V. and Kühl, A.A. and Stein, U. and Vieth, M. and Birchmeier, W. and Leutz, A.
Life Science Alliance 2
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February 2019
Codon bias confers stability to human mRNAs.
Hia, F. and Yang, S.F. and Shichino, Y. and Yoshinaga, M. and Murakawa, Y. and Vandenbon, A. and Fukao, A. and Fujiwara, T. and Landthaler, M. and Natsume, T. and Adachi, S. and Iwasaki, S. and Takeuchi, O.
EMBO Reports 20
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5 November 2019
Sample preservation and storage significantly impact taxonomic and functional profiles in metaproteomics studies of the human gut microbiome.
Hickl, O. and Heintz-Buschart, A. and Trautwein-Schult, A. and Hercog, R. and Bork, P. and Wilmes, P. and Becher, D.
Microorganisms 7
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19 September 2019
Antibiotics-induced monodominance of a novel gut bacterial order.
Hildebrand, F. and Moitinho-Silva, L. and Blasche, S. and Jahn, M.T.T. and Gossmann, T.I. and Heuerta Cepas, J. and Hercog, R. and Luetge, M. and Bahram, M. and Pryszlak, A. and Alves, R.J. and Waszak, S.M. and Zhu, A. and Ye, L. and Costea, P.I. and Aalvink, S. and Belzer, C. and Forslund, S.K. and Sunagawa, S. and Hentschel, U. and Merten, C. and Patil, K.R. and Benes, V. and Bork, P.
Gut 68
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9 September 2019
Regenerative potential of adipocytes in hypertrophic scars is mediated by myofibroblast reprogramming.
Hoerst, K. and van den Broek, L. and Sachse, C. and Klein, O. and von Fritschen, U. and Gibbs, S. and Hedtrich, S.
Journal of Molecular Medicine 97
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1 June 2019
A synthetic epoxyeicosatrienoic acid analogue prevents the initiation of ischemic acute kidney injury.
Hoff, U. and Bubalo, G. and Fechner, M. and Blum, M. and Zhu, Y. and Pohlmann, A. and Hentschel, J. and Arakelyan, K. and Seeliger, E. and Flemming, B. and Gürgen, D. and Rothe, M. and Niendorf, T. and Manthati, V.L. and Falck, J.R. and Haase, M. and Schunck, W.H. and Dragun, D.
Acta Physiologica 227
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October 2019
Autoantibodies activating the β2-adrenergic receptor characterize patients with primary and secondary glaucoma.
Hohberger, B. and Kunze, R. and Wallukat, G. and Kara, K. and Mardin, C.Y. and Lämmer, R. and Schlötzer-Schrehardt, U. and Hosari, S. and Horn, F. and Munoz, L. and Herrmann, M.
Frontiers in Immunology 10
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October 2019
RNA tomography for spatially resolved transcriptomics (Tomo-seq).
Holler, K. and Junker, J.P.
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Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial.
Horwitz, S. and O'Connor, O.A. and Pro, B. and Illidge, T. and Fanale, M. and Advani, R. and Bartlett, N.L. and Christensen, J.H. and Morschhauser, F. and Domingo-Domenech, E. and Rossi, G. and Kim, W.S. and Feldman, T. and Lennard, A. and Belada, D. and Illés, A. and Tobinai, K. and Tsukasaki, K. and Yeh, S.P. and Shustov, A. and Hüttmann, A. and Savage, K.J. and Yuen, S. and Iyer, S. and Zinzani, P.L. and Hua, Z. and Little, M. and Rao, S. and Woolery, J. and Manley, T. and Trümper, L.
Lancet 393
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19 January 2019
Genetics of intellectual disability in consanguineous families.
Hu, H. and Kahrizi, K. and Musante, L. and Fattahi, Z. and Herwig, R. and Hosseini, M. and Oppitz, C. and Abedini, S.S. and Suckow, V. and Larti, F. and Beheshtian, M. and Lipkowitz, B. and Akhtarkhavari, T. and Mehvari, S. and Otto, S. and Mohseni, M. and Arzhangi, S. and Jamali, P. and Mojahedi, F. and Taghdiri, M. and Papari, E. and Soltani Banavandi, M.J. and Akbari, S. and Tonekaboni, S.H. and Dehghani, H. and Ebrahimpour, M.R. and Bader, I. and Davarnia, B. and Cohen, M. and Khodaei, H. and Albrecht, B. and Azimi, S. and Zirn, B. and Bastami, M. and Wieczorek, D. and Bahrami, G. and Keleman, K. and Vahid, L.N. and Tzschach, A. and Gärtner, J. and Gillessen-Kaesbach, G. and Varaghchi, J.R. and Timmermann, B. and Pourfatemi, F. and Jankhah, A. and Chen, W. and Nikuei, P. and Kalscheuer, V.M. and Oladnabi, M. and Wienker, T.F. and Ropers, H.H. and Najmabadi, H.
Molecular Psychiatry 24
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July 2019
GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.
Hu, X. and Matsumoto, K. and Jung, R.S. and Weston, T.A. and Heizer, P.J. and He, C. and Sandoval, N.P. and Allan, C.M. and Tu, Y. and Vinters, H.V. and Liau, L.M. and Ellison, R.M. and Morales, J.E. and Baufeld, L.J. and Bayley, N.A. and He, L. and Betsholtz, C. and Beigneux, A.P. and Nathanson, D.A. and Gerhardt, H. and Young, S.G. and Fong, L.G. and Jiang, H.
eLife 8
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6 June 2019
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
Huang, A. and Shinde, P.V. and Huang, J. and Senff, T. and Xu, H.C. and Margotta, C. and Häussinger, D. and Willnow, T.E. and Zhang, J. and Pandyra, A.A. and Timm, J. and Weggen, S. and Lang, K.S. and Lang, P.A.
JCI Insight 4
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5 September 2019
Vibrational spectroscopy as a powerful tool for follow-up immunoadsorption therapy treatment of dilated cardiomyopathy - a case report.
Huang, J. and Ramoji, A. and Guo, S. and Bocklitz, T. and Boivin-Jahns, V. and Möller, J. and Kiehntopf, M. and Noutsias, M. and Popp, J. and Neugebauer, U.
Analyst 145
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15 November 2019
Early hearing loss upon disruption of Slc4a10 in C57BL/6 mice.
Huebner, A.K. and Maier, H. and Maul, A. and Nietzsche, S. and Herrmann, T. and Praetorius, J. and Hübner, C.A.
Journal of the Association for Research in Otolaryngology 20
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June 2019
eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses.
Huerta-Cepas, J. and Szklarczyk, D. and Heller, D. and Hernández-Plaza, A. and Forslund, S.K. and Cook, H. and Mende, D.R. and Letunic, I. and Rattei, T. and Jensen, L.J. and von Mering, C. and Bork, P.
Nucleic Acids Research 47
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8 January 2019
BigStitcher: reconstructing high-resolution image datasets of cleared and expanded samples.
Hörl, D. and Rojas Rusak, F. and Preusser, F. and Tillberg, P. and Randel, N. and Chhetri, R.K. and Cardona, A. and Keller, P.J. and Harz, H. and Leonhardt, H. and Treier, M. and Preibisch, S.
Nature Methods 16
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September 2019
Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifications.
Ibarra Urizar, A. and Prause, M. and Wortham, M. and Sui, Y. and Thams, P. and Sander, M. and Christensen, G.L. and Billestrup, N.
Molecular and Cellular Endocrinology 496
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1 October 2019
Discontinuous shear-thinning in adhesive dispersions.
Irani, E. and Chaudhuri, P. and Heussinger, C.
Physical Review Fluids 4
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18 July 2019
Evaluation of a rare glucose-dependent insulinotropic polypeptide receptor variant in a patient with diabetes.
Jacobi, S.F. and Khajavi, N. and Kleinau, G. and Teumer, A. and Scheerer, P. and Homuth, G. and Völzke, H. and Wiegand, S. and Kühnen, P. and Krude, H. and Gong, M. and Raile, K. and Biebermann, H.
Diabetes Obesity and Metabolism 21
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May 2019
Multiple sclerosis-related fatigue: altered resting-state functional connectivity of the ventral striatum and dorsolateral prefrontal cortex.
Jaeger, S. and Paul, F. and Scheel, M. and Brandt, A. and Heine, J. and Pach, D. and Witt, C.M. and Bellmann-Strobl, J. and Finke, C.
Multiple Sclerosis Journal 25
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April 2019
A combined miRNA-piRNA signature to detect Alzheimer's disease.
Jain, G. and Stuendl, A. and Rao, P. and Berulava, T. and Pena Centeno, T. and Kaurani, L. and Burkhardt, S. and Delalle, I. and Kornhuber, J. and Hüll, M. and Maier, W. and Peters, O. and Esselmann, H. and Schulte, C. and Deuschle, C. and Synofzik, M. and Wiltfang, J. and Mollenhauer, B. and Maetzler, W. and Schneider, A. and Fischer, A.
Translational Psychiatry 9
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7 October 2019
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML.
Jakobsen, J.S. and Laursen, L.G. and Schuster, M.B. and Pundhir, S. and Schoof, E. and Ge, Y. and d'Altri, T. and Vitting-Seerup, K. and Rapin, N. and Gentil, C. and Jendholm, J. and Theilgaard-Mönch, K. and Reckzeh, K. and Bullinger, L. and Döhner, K. and Hokland, P. and Fitzgibbon, J. and Porse, B.T.
Science Advances 5
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July 2019
Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia.
James, A.R. and Schroeder, M.P. and Neumann, M. and Bastian, L. and Eckert, C. and Gökbuget, N. and Tanchez, J.O. and Schlee, C. and Isaakidis, K. and Schwartz, S. and Burmeister, T. and von Stackelberg, A. and Rieger, M.A. and Göllner, S. and Horstman, M. and Schrappe, M. and Kirschner-Schwabe, R. and Brüggemann, M. and Müller-Tidow, C. and Serve, H. and Akalin, A. and Baldus, C.D.
Journal of Hematology & Oncology 12
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14 January 2019
Fabrication of kidney proximal tubule grafts using biofunctionalized electrospun polymer scaffolds.
Jansen, K. and Castilho, M. and Aarts, S. and Kaminski, M.M. and Lienkamp, S.S. and Pichler, R. and Malda, J. and Vermonden, T. and Jansen, J. and Masereeuw, R.
Macromolecular Bioscience 19
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February 2019
Myelinoclastic diffuse sclerosis (Schilder's disease) is immunologically distinct from multiple sclerosis: results from retrospective analysis of 92 lumbar punctures.
Jarius, S. and Haas, J. and Paul, F. and Wildemann, B.
Journal of Neuroinflammation 16
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28 February 2019
A network of microRNAs acts to promote cell cycle exit and differentiation of human pancreatic endocrine cells.
Jin, W. and Mulas, F. and Gaertner, B. and Sui, Y. and Wang, J. and Matta, I. and Zeng, C. and Vinckier, N. and Wang, A. and Nguyen-Ngoc, K.V. and Chiou, J. and Kaestner, K.H. and Frazer, K.A. and Carrano, A.C. and Shih, H.P. and Sander, M.
iScience 21
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22 November 2019
Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress.
Jochner, M.C.E. and An, J. and Lättig-Tünnemann, G. and Kirchner, M. and Dagane, A. and Dittmar, G. and Dirnagl, U. and Eickholt, B.J. and Harms, C.
Scientific Reports 9
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28 February 2019
Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS).
Johnen, A. and Bürkner, P.C. and Landmeyer, N.C. and Ambrosius, B. and Calabrese, P. and Motte, J. and Hessler, N. and Antony, G. and König, I.R. and Klotz, L. and Hoshi, M.M. and Aly, L. and Groppa, S. and Luessi, F. and Paul, F. and Tackenberg, B. and Bergh, F.T. and Kümpfel, T. and Tumani, H. and Stangel, M. and Weber, F. and Bayas, A. and Wildemann, B. and Heesen, C. and Zettl, U.K. and Zipp, F. and Hemmer, B. and Meuth, S.G. and Gold, R. and Wiendl, H. and Salmen, A.
Journal of Neurology 266
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February 2019
Lymphocyte characterization of decidua basalis spiral arteries with acute atherosis in preeclamptic and normotensive pregnancies.
Johnsen, G.M. and Størvold, G.L. and Alnaes-Katjavivi, P.H. and Roald, B. and Golic, M. and Dechend, R. and Redman, C.W.G. and Staff, A.C.
Journal of Reproductive Immunology 132
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April 2019
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Joshi, K. and de Massy, M.R. and Ismail, M. and Reading, J.L. and Uddin, I. and Woolston, A. and Hatipoglu, E. and Oakes, T. and Rosenthal, R. and Peacock, T. and Ronel, T. and Noursadeghi, M. and Turati, V. and Furness, A.J.S. and Georgiou, A. and Wong, Y.N.S. and Ben Aissa, A. and Sunderland, M.W. and Jamal-Hanjani, M. and Veeriah, S. and Birkbak, N.J. and Wilson, G.A. and Hiley, C.T. and Ghorani, E. and Guerra-Assunção, J.A. and Herrero, J. and Enver, T. and Hadrup, S.R. and Hackshaw, A. and Peggs, K.S. and McGranahan, N. and Swanton, C. and Quezada, S.A. and Chain, B.
Nature Medicine 25
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October 2019
Multiple two-photon targeted whole-cell patch-clamp recordings from monosynaptically connected neurons in vivo.
Jouhanneau, J.S. and Poulet, J.F.A.
Frontiers in Synaptic Neuroscience 11
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May 2019
In vivo-mimicking microfluidic perfusion culture of pancreatic islet spheroids.
Jun, Y. and Lee, J.S. and Choi, S. and Yang, J.H. and Sander, M. and Chung, S. and Lee, S.H.
Science Advances 5
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1 November 2019
Human gestational N-methyl-d-aspartate receptor autoantibodies impair neonatal murine brain function.
Jurek, B. and Chayka, M. and Kreye, J. and Lang, K. and Kraus, L. and Fidzinski, P. and Kornau, H.C. and Dao, L.M. and Wenke, N.K. and Long, M. and Rivalan, M. and Winter, Y. and Leubner, J. and Herken, J. and Mayer, S. and Mueller, S. and Boehm-Sturm, P. and Dirnagl, U. and Schmitz, D. and Kölch, M. and Prüss, H.
Annals of Neurology 86
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November 2019
SSBP1 mutations in dominant optic atrophy with variable retinal degeneration.
Jurkute, N. and Leu, C. and Pogoda, H.M. and Arno, G. and Robson, A.G. and Nürnberg, G. and Altmüller, J. and Thiele, H. and Motameny, S. and Toliat, M.R. and Powell, K. and Höhne, W. and Michaelides, M. and Webster, A.R. and Moore, A.T. and Hammerschmidt, M. and Nürnberg, P. and Yu-Wai-Man, P. and Votruba, M.
Annals of Neurology 86
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September 2019
Immunhistochemische Analyse von Bcl-2, nukleärem S100A4, MITF und Ki67 zur Risikostratifizierung von Melanomen im Frühstadium - ein kombinierter immunhistochemischer Score.
Jurmeister, P. and Bockmayr, M. and Treese, C. and Stein, U. and Lenze, D. and Jöhrens, K. and Friedling, F. and Dietel, M. and Klauschen, F. and Marsch, W. and Fiedler, E. and von Laffert, M.
Journal der Deutschen Dermatologischen Gesellschaft 17
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August 2019
Immunohistochemical analysis of Bcl-2, nuclear S100A4, MITF and Ki67 for risk stratification of early-stage melanoma - a combined IHC score for melanoma risk stratification.
Jurmeister, P. and Bockmayr, M. and Treese, C. and Stein, U. and Lenze, D. and Jöhrens, K. and Friedling, F. and Dietel, M. and Klauschen, F. and Marsch, W. and Fiedler, E. and von Laffert, M.
Journal der Deutschen Dermatologischen Gesellschaft 17
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August 2019
Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations.
Jutzi, J.S. and Basu, T. and Pellmann, M. and Kaiser, S. and Steinemann, D. and Sanders, M.A. and Hinai, A.S.A. and Zeilemaker, A. and Bojtine Kovacs, S. and Koellerer, C. and Ostendorp, J. and Aumann, K. and Wang, W. and Raffoux, E. and Cassinat, B. and Bullinger, L. and Schlegelberger, B. and Valk, P.J.M. and Pahl, H.L.
Blood 133
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18 April 2019
Angiotensin-(1-7) receptor Mas in hemodynamic and thermoregulatory dysfunction after high-level spinal cord injury in mice: a pilot study.
Järve, A. and Todiras, M. and Kny, M. and Fischer, F.I. and Kraemer, J.F. and Wessel, N. and Plehm, R. and Fielitz, J. and Alenina, N. and Bader, M.
Frontiers in Physiology 9
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January 2019
Distinct roles of angiotensin receptors in autonomic dysreflexia following high-level spinal cord injury in mice.
Järve, A. and Todiras, M. and Lian, X and Filippelli-Silva, R. and Qadri, F. and Martin, R.P. and Gollasch, M. and Bader, M.
Experimental Neurology 311
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January 2019
Cytotoxic effects of rabbit anti-thymocyte globulin preparations on primary human thymic epithelial cells.
Kaebisch, E.M. and Cho, M.Y. and Oh, Y.S. and Olfe, L.I. and Szyska, M. and Becker, S.C. and Reinke, P. and Volk, H.D. and Gillissen, B. and Bullinger, L. and Thiel, A. and Na, I.K.
Transplantation 103
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November 2019
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors.
Kaffes, I. and Szulzewsky, F. and Chen, Z. and Herting, C.J. and Gabanic, B. and Velázquez Vega, J.E. and Shelton, J. and Switchenko, J.M. and Ross, J.L. and McSwain, L.F. and Huse, J.T. and Westermark, B. and Nelander, S. and Forsberg-Nilsson, K. and Uhrbom, L. and Maturi, N.P. and Cimino, P.J. and Holland, E.C. and Kettenmann, H. and Brennan, C.W. and Brat, D.J. and Hambardzumyan, D.
OncoImmunology 8
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22 August 2019
Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ.
Kalasova, I. and Hanzlikova, H. and Gupta, N. and Li, Y. and Altmüller, J. and Reynolds, J.J. and Stewart, G.S. and Wollnik, B. and Yigit, G. and Caldecott, K.W.
Neurology Genetics 5
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April 2019
Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined.
Kaleviste, E. and Saare, M. and Leahy, T.R. and Bondet, V. and Duffy, D. and Mogensen, T. and Jørgensen, S.E. and Nurm, H. and Ip, W. and Davies, E.G. and Sauer, S. and Syvänen, A.C. and Milani, L. and Peterson, P. and Kisand, K.
European Journal of Immunology 49
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May 2019
Hypertonicity-affected genes are differentially expressed in clear cell renal cell carcinoma and correlate with cancer-specific survival.
Kandabarau, S. and Leiz, J. and Krohn, K. and Winter, S. and Bedke, J. and Schwab, M. and Schaeffeler, E. and Edemir, B.
Cancers 12
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18 December 2019
The association between frailty and MRI features of cerebral small vessel disease.
Kant, I.M.J. and Mutsaerts, H.J.M.M. and van Montfort, S.J.T. and Jaarsma-Coes, M.G. and Witkamp, T.D. and Winterer, G. and Spies, C.D. and Hendrikse, J. and Slooter, A.J.C. and de Bresser, J.
Scientific Reports 9
(1): 11343.
5 August 2019
MTrack: automated detection, tracking, and analysis of dynamic microtubules.
Kapoor, V. and Hirst, W.G. and Hentschel, C. and Preibisch, S. and Reber, S.
Scientific Reports 9
(1): 3794.
7 March 2019
Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling.
Karabacak Calviello, A. and Hirsekorn, A. and Wurmus, R. and Yusuf, D. and Ohler, U.
Genome Biology 20
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21 February 2019
Biallelic variant in AGTPBP1 causes infantile lower motor neuron degeneration and cerebellar atrophy.
Karakaya, M. and Paketci, C. and Altmueller, J. and Thiele, H. and Hoelker, I. and Yis, U. and Wirth, B.
American Journal of Medical Genetics Part A 179
(8): 1580-1584.
August 2019
Recruitment of histone methyltransferase Ehmt1 to Foxp3 TSDR counteracts differentiation of induced regulatory T cells.
Karl, M. and Sommer, C. and Gabriel, C.H. and Hecklau, K. and Venzke, M. and Hennig, A.F. and Radbruch, A. and Selbach, M. and Baumgrass, R.
Journal of Molecular Biology 431
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6 September 2019
Lyophilization of synthetic gene carriers.
Kasper, J.C. and Hedtrich, S. and Friess, W.
Methods in Molecular Biology 1943
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2019
Vinylphosphonites for staudinger-induced chemoselective peptide cyclization and functionalization.
Kasper, M.A and Glanz, M. and Oder, A. and Schmieder, P. and von Kries, J.P. and Hackenberger, C.P.R.
Chemical Science 10
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7 July 2019
Impact of brief prewarming on anesthesia-related core-temperature drop, hemodynamics, microperfusion and postoperative ventilation in cytoreductive surgery of ovarian cancer: a randomized trial.
Kaufner, L. and Niggemann, P. and Baum, T. and Casu, S. and Sehouli, J. and Bietenbeck, A. and Boschmann, M. and Spies, C.D. and Henkelmann, A. and von Heymann, C.
BMC Anesthesiology 19
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22 August 2019
HSPA6: s new autosomal recessive candidate gene for the VATER/VACTERL malformation spectrum.
Kause, F. and Zhang, R. and Ludwig, M. and Schmiedeke, E. and Rissmann, A. and Thiele, H. and Altmueller, J. and Herms, S. and Hilger, A.C. and Hildebrandt, F. and Reutter, H.
Birth Defects Research 111
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1 June 2019
Role of ryanodine type 2 receptors in elementary Ca(2+) signaling in arteries and vascular adaptive responses.
Kaßmann, M. and Szijártó, I.A. and García-Prieto, C.F. and Fan, G. and Schleifenbaum, J. and Anistan, Y.M. and Tabeling, C. and Shi, Y. and le Noble, F. and Witzenrath, M. and Huang, Y. and Markó, L. and Nelson, M.T. and Gollasch, M.
Journal of the American Heart Association 8
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7 May 2019
Hyperkaliämie - Ursachen, Diagnostik und Therapie [Hyperkalemia - causes, diagnostic evaluation and treatment].
Kettritz, R.
Deutsche Medizinische Wochenschrift 144
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February 2019
Seltene Elektrolytstörungen [Rare electrolyte disorders].
Kettritz, R. and Luft, F.C.
Nephrologe 14
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March 2019
The incidence of acute kidney injury and associated hospital mortality: a retrospective cohort study of over 100 000 patients at Berlin's Charité Hospital.
Khadzhynov, D. and Schmidt, D. and Hardt, J. and Rauch, G. and Gocke, P. and Eckardt, K.U. and Schmidt-Ott, K.M.
Deutsches Aerzteblatt International 116
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31 May 2019
Histological and functional comparisons of four anatomical regions of porcine skin with human abdominal skin.
Khiao In, M. and Richardson, K.C. and Loewa, A. and Hedtrich, S. and Kaessmeyer, S. and Plendl, J.
Anatomia Histologia Embryologia 48
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May 2019
Disruption of PHF21A causes syndromic intellectual disability with craniofacial anomalies, epilepsy, hypotonia, and neurobehavioral problems including autism.
Kim, H.G. and Rosenfeld, J.A. and Scott, D.A. and Bénédicte, G. and Labonne, J.D. and Brown, J. and McGuire, M. and Mahida, S. and Naidu, S. and Gutierrez, J. and Lesca, G. and des Portes, V. and Bruel, A.L. and Sorlin, A. and Xia, F. and Capri, Y. and Muller, E. and McKnight, D. and Torti, E. and Rüschendorf, F. and Hummel, O. and Islam, Z. and Kolatkar, P.R. and Layman, L.C. and Ryu, D. and Kong, I.K. and Madan-Khetarpal, S. and Kim, C.H.
Molecular Autism 10
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22 October 2019
A protocol for laser microdissection (LMD) followed by transcriptome analysis of plant reproductive tissue in phylogenetically distant angiosperms.
Kivivirta, K. and Herbert, D. and Lange, M. and Beuerlein, K. and Altmüller, J. and Becker, A.
Plant Methods 15
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16 December 2019
Quantitative grip force assessment of muscular weakness in chronic inflammatory demyelinating polyneuropathy.
Klehmet, J. and Beutner, S. and Hoffmann, S. and Dornauer, M. and Paul, F. and Reilmann, R. and Brandt, A.U. and Meisel, A.
BMC Neurology 19
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8 June 2019
TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor.
Klein, S. and Kleine, C.E. and Pieper, A. and Granzow, M. and Gautsch, S. and Himmit, M. and Kahrmann, K. and Schierwagen, R. and Uschner, F.E. and Magdaleno, F. and Naoum, M.E. and Kristiansen, Glen and Walther, T. and Bader, M. and Sauerbruch, T. and Trebicka, J.
Scientific Reports 9
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12 August 2019
Dynamics of chromatin and transcription during transient depletion of the RSC chromatin remodeling complex.
Klein-Brill, A. and Joseph-Strauss, D. and Appleboim, A. and Friedman, N.
Cell Reports 26
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2 January 2019
Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB/W F1 mice.
Klocke, J. and Ulu, A. and Wu, K. and Rudolph, B. and Dragun, D. and Gollasch, M. and Schunck, W.H. and Hammock, B.D. and Riemekasten, G. and Enghard, P.
Scientific Reports 9
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20 June 2019
m(6)A-mRNA methylation regulates cardiac gene expression and cellular growth.
Kmietczyk, V. and Riechert, E. and Kalinski, L. and Boileau, E. and Malovrh, E. and Malone, B. and Gorska, A. and Hofmann, C. and Varma, E. and Jürgensen, L. and Kamuf-Schenk, V. and Altmüller, J. and Tappu, R. and Busch, M. and Most, P. and Katus, H.A. and Dieterich, C. and Völkers, M.
Life Science Alliance 2
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April 2019
Interferon-γ receptor signaling in dendritic cells restrains spontaneous proliferation of CD4(+) T cells in chronic lymphopenic mice.
Knop, L. and Frommer, C. and Stoycheva, D. and Deiser, K. and Kalinke, U. and Blankenstein, T. and Kammertoens, T. and Dunay, I.R. and Schüler, T.
Frontiers in Immunology 10
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7 February 2019
Ninjurin1 regulates striated muscle growth and differentiation.
Kny, M. and Csályi, K.D. and Klaeske, K. and Busch, K. and Meyer, A.M. and Merks, A.M. and Darm, K. and Dworatzek, E. and Fliegner, D. and Baczko, I. and Regitz-Zagrosek, V. and Butter, C. and Luft, F.C. and Panáková, D. and Fielitz, J.
PLoS ONE 14
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15 May 2019
Design and characterization of dietary assessment in the German National Cohort.
Knüppel, S. and Clemens, M. and Conrad, J. and Gastell, S. and Michels, K.B. and Leitzmann, M. and Krist, L. and Pischon, T. and Krause, G. and Ahrens, W. and Ebert, N. and Jöckel, K.H. and Kluttig, A. and Obi, N. and Kaaks, R. and Lieb, W. and Schipf, S. and Brenner, H. and Heuer, T. and Harttig, U. and Linseisen, J. and Nöthlings, U. and Boeing, H.
European Journal of Clinical Nutrition 73
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November 2019
Cognitive impairment is associated with absolute intraoperative frontal α-band power but not with baseline α-band power: a pilot study.
Koch, S. and Feinkohl, I. and Chakravarty, S. and Windmann, V. and Lichtner, G. and Pischon, T. and Brown, E.N. and Spies, C.
Dementia and Geriatric Cognitive Disorders 48
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December 2019
Biallelic mutation in MYH7 and MYBPC3 leads to severe cardiomyopathy with left ventricular noncompaction phenotype.
Kolokotronis, K. and Kühnisch, J. and Klopocki, E. and Dartsch, J. and Rost, S. and Huculak, C. and Mearini, G. and Störk, S. and Carrier, L. and Klaassen, S. and Gerull, B.
Human Mutation 40
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August 2019
Rare variants in BNC2 are implicated in autosomal-dominant congenital lower urinary-tract obstruction.
Kolvenbach, C.M. and Dworschak, G.C. and Frese, S. and Japp, A.S. and Schuster, P. and Wenzlitschke, N. and Yilmaz, Ö. and Lopes, F.M. and Pryalukhin, A. and Schierbaum, L. and van der Zanden, L.F.M. and Kause, F. and Schneider, R. and Taranta-Janusz, K. and Szczepańska, M. and Pawlaczyk, K. and Newman, W.G. and Beaman, G.M. and Stuart, H.M. and Cervellione, R.M. and Feitz, W.F.J. and van Rooij, I.A.L.M. and Schreuder, M.F. and Steffens, M. and Weber, S. and Merz, W.M. and Feldkötter, M. and Hoppe, B. and Thiele, H. and Altmüller, J. and Berg, C. and Kristiansen, G. and Ludwig, M. and Reutter, H. and Woolf, A.S. and Hildebrandt, F. and Grote, P. and Zaniew, M. and Odermatt, B. and Hilger, A.C.
American Journal of Human Genetics 104
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2 May 2019
Renal fibrosis, immune cell infiltration and changes of TRPC channel expression after unilateral ureteral obstruction in Trpc6-/- mice.
Kong, W. and Haschler, T.N. and Nürnberg, B. and Krämer, S. and Gollasch, M. and Markó, L.
Cellular Physiology and Biochemistry 52
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2019
Prediction of circulating adipokine levels based on body fat compartments and adipose tissue gene expression.
Konigorski, S. and Janke, J. and Drogan, D. and Bergmann, M.M. and Hierholzer, J. and Kaaks, R. and Boeing, H. and Pischon, T.
Obesity Facts 12
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December 2019
Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses.
Kosciuczuk, E.M. and Mehrotra, S. and Saleiro, D. and Kroczynska, B. and Majchrzak-Kita, B. and Lisowski, P. and Driehaus, C. and Rogalska, A. and Turner, A. and Lienhoop, T. and Gius, D. and Fish, E.N. and Vassilopoulos, A. and Platanias, L.C.
Journal of Biological Chemistry 294
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18 January 2019
MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis.
Kotelnikova, E. and Kiani, N.A. and Messinis, D. and Pertsovskaya, I. and Pliaka, V. and Bernardo-Faura, M. and Rinas, M. and Vila, G. and Zubizarreta, I. and Pulido-Valdeolivas, I. and Sakellaropoulos, T. and Faigle, W. and Silberberg, G. and Masso, M. and Stridh, P. and Behrens, J. and Olsson, T. and Martin, R. and Paul, F. and Alexopoulos, L.G. and Saez-Rodriguez, J. and Tegner, J. and Villoslada, P.
Proceedings of the National Academy of Sciences of the United States of America 116
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7 May 2019
Chaperone protein HSC70 regulates intercellular transfer of Y chromosome antigen DBY.
Kretschmann, S. and Herda, S. and Bruns, H. and Russ, J. and van der Meijden, E.D. and Schlötzer-Schrehardt, U. and Griffioen, M. and Na, I.K. and Mackensen, A. and Kremer, A.N.
Journal of Clinical Investigation 129
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1 July 2019
Less is more - estimation of the number of strides required to assess gait variability in spatially confined settings.
Kroneberg, D. and Elshehabi, M. and Meyer, A.C. and Otte, K. and Doss, S. and Paul, F. and Nussbaum, S. and Berg, D. and Kühn, A.A. and Maetzler, W. and Schmitz-Hübsch, T.
Frontiers in Aging Neuroscience 10
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21 January 2019
A curated resource for phosphosite-specific signature analysis.
Krug, K. and Mertins, P. and Zhang, B. and Hornbeck, P. and Raju, R. and Ahmad, R. and Szucs, M. and Mundt, F. and Forestier, D. and Jane-Valbuena, J. and Keshishian, H. and Gillette, M.A. and Tamayo, P. and Mesirov, J.P. and Jaffe, J.D. and Carr, S.A. and Mani, D.R.
Molecular & Cellular Proteomics 18
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1 March 2019
AltamISA: a Python API for ISA-Tab files.
Kuhring, M. and Nieminen, M. and Kirwan, J. and Beule, D. and Holtgrewe, M.
Journal of Open Source Software 4
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20 August 2019
Cardiac magnetic resonance stress perfusion imaging for evaluation of patients with chest pain.
Kwong, R.Y. and Ge, Y. and Steel, K. and Bingham, S. and Abdullah, S. and Fujikura, K. and Wang, W. and Pandya, A. and Chen, Y.Y. and Mikolich, J.R. and Boland, S. and Arai, A.E. and Bandettini, W.P. and Shanbhag, S.M. and Patel, A.R. and Narang, A. and Farzaneh-Far, A. and Romer, B. and Heitner, J.F. and Ho, J.Y. and Singh, J. and Shenoy, C. and Hughes, A. and Leung, S.W. and Marji, M. and Gonzalez, J.A. and Mehta, S. and Shah, D.J. and Debs, D. and Raman, S.V. and Guha, A. and Ferrari, V.A. and Schulz-Menger, J. and Hachamovitch, R. and Stuber, M. and Simonetti, O.P.
Journal of the American College of Cardiology 74
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8 October 2019
Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3.
Kühnisch, J. and Herbst, C. and Al-Wakeel-Marquard, N. and Dartsch, J. and Holtgrewe, M. and Baban, A. and Mearini, G. and Hardt, J. and Kolokotronis, K. and Gerull, B. and Carrier, L. and Beule, D. and Schubert, S. and Messroghli, D. and Degener, F. and Berger, F. and Klaassen, S.
Clinical Genetics 96
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December 2019
Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.
LaBranche, C.C. and Henderson, R. and Hsu, A. and Behrens, S. and Chen, X. and Zhou, T. and Wiehe, K. and Saunders, K.O. and Alam, S.M. and Bonsignori, M. and Borgnia, M.J. and Sattentau, Q.J. and Eaton, A. and Greene, K. and Gao, H. and Liao, H.X. and Williams, W.B. and Peacock, J. and Tang, H. and Perez, L.G. and Edwards, R.J. and Kepler, T.B. and Korber, B.T. and Kwong, P.D. and Mascola, J.R. and Acharya, P. and Haynes, B.F. and Montefiori, D.C.
PLoS Pathogens 15
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17 September 2019
Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat.
Labi, V. and Peng, S. and Klironomos, F. and Munschauer, M. and Kastelic, N. and Chakraborty, T. and Schoeler, K. and Derudder, E. and Martella, M. and Mastrobuoni, G. and Hernandez-Miranda, L.R. and Lahmann, I. and Kocks, C. and Birchmeier, C. and Kempa, S. and Quintanilla-Martinez de Fend, L. and Landthaler, M. and Rajewsky, N. and Rajewsky, K.
Genes & Development 33
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7 November 2019
Cerebral microbleeds are not associated with postoperative delirium and postoperative cognitive dysfunction in older individuals.
Lachmann, G. and Kant, I. and Lammers, F. and Windmann, V. and Spies, C. and Speidel, S. and Borchers, F. and Hadzidiakos, D. and Hendrikse, J. and Winterer, G. and de Bresser, J.
PLoS ONE 14
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14 June 2019
The accumulation of deficits approach to describe frailty.
Lachmann, R. and Stelmach-Mardas, M. and Bergmann, M.M. and Bernigau, W. and Weber, D. and Pischon, T. and Boeing, H.
PLoS ONE 14
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15 October 2019
Impact of diabetic stress conditions on renal cell metabolome.
Lagies, S. and Pichler, R. and Bork, T. and Kaminski, M.M. and Troendle, K. and Zimmermann, S. and Huber, T.B. and Walz, G. and Lienkamp, S.S. and Kammerer, B.
Cells 8
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24 September 2019
Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells.
Lahmann, I. and Bröhl, D. and Zyrianova, T. and Isomura, A. and Czajkowski, M.T. and Kapoor, V. and Griger, J. and Ruffault, P.L. and Mademtzoglou, D. and Zammit, P.S. and Wunderlich, T. and Spuler, S. and Kühn, R. and Preibisch, S. and Wolf, J. and Kageyama, R. and Birchmeier, C.
Genes & Development 33
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1 May 2019
Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly.
Lahrouchi, N. and George, A. and Ratbi, I. and Schneider, R. and Elalaoui, S.C. and Moosa, S. and Bharti, S. and Sharma, R. and Abu-Asab, M. and Onojafe, F. and Adadi, N. and Lodder, E.M. and Laarabi, F.Z. and Lamsyah, Y. and Elorch, H. and Chebbar, I. and Postma, A.V. and Lougaris, V. and Plebani, A. and Altmueller, J. and Kyrieleis, H. and Meiner, V. and McNeill, H. and Bharti, K. and Lyonnet, S. and Wollnik, B. and Henrion-Caude, A. and Berraho, A. and Hildebrandt, F. and Bezzina, C.R. and Brooks, B.P. and Sefiani, A.
Nature Communications 10
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12 March 2019
Collagen I-based scaffolds negatively impact fracture healing in a mouse-osteotomy-model although used routinely in research and clinical application.
Lang, A. and Kirchner, M. and Stefanowski, J. and Durst, M. and Weber, M.C. and Pfeiffenberger, M. and Damerau, A. and Hauser, A.E. and Hoff, P. and Duda, G.N. and Buttgereit, F. and Schmidt-Bleek, K. and Gaber, T.
Acta Biomaterialia 86
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1 March 2019
Direct zinc finger protein persulfidation by H(2)S is facilitated by Zn(2+).
Lange, M. and Ok, K. and Shimberg, G.D. and Bursac, B. and Markó, L. and Ivanović-Burmazović, I. and Michel, S. and Filipovic, M.R.
Angewandte Chemie International Edition 58
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11 June 2019
Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking.
Lareau, C.A. and Ludwig, L.S. and Sankaran, V.G.
Blood Advances 3
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23 December 2019
Social networks and protest participation: evidence from 130 million Twitter users.
Larson, J.M. and Nagler, J. and Ronen, J. and Tucker, J.A.
American Journal of Political Science 63
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July 2019
Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells.
Le, T.T.H. and Tran, N.T. and Dao, T.M.L. and Nguyen, D.D. and Do, H.D. and Ha, T.L. and Kühn, R. and Nguyen, T.L. and Rajewsky, K. and Chu, V.T.
Frontiers in Genetics 10
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July 2019
Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma.
Lee, A.Y.L. and Dubois, C.L. and Sarai, K. and Zarei, S. and Schaeffer, D.F. and Sander, M. and Kopp, J. L.
Gut 68
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March 2019
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.
Lee, J. and Termglinchan, V. and Diecke, S. and Itzhaki, I. and Lam, C.K. and Garg, P. and Lau, E. and Greenhaw, M. and Seeger, T. and Wu, H. and Zhang, J.Z and Chen, X. and Gil, I.P. and Ameen, M. and Sallam, K. and Rhee, J.W. and Churko, J.M. and Chaudhary, R. and Chour, T. and Wang, P.J. and Snyder, M.P. and Chang, H.Y. and Karakikes, I. and Wu, J.C.
Nature 572
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15 August 2019
FLAM-seq: full-length mRNA sequencing reveals principles of poly(A) tail length control.
Legnini, I. and Alles, J. and Karaiskos, N. and Ayoub, S. and Rajewsky, N.
Nature Methods 16
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September 2019
The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G.
Leisegang, M.S. and Gu, L. and Preussner, J. and Günther, S. and Hitzel, J. and Ratiu, C. and Weigert, A. and Chen, W. and Schwarz, E.C. and Looso, M. and Fork, C. and Brandes, R.P.
FEBS Letters 593
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March 2019
Using SMOG 2 to simulate complex biomolecular assemblies.
Levi, M. and Bandarkar, P. and Yang, H. and Wang, A. and Mohanty, U. and Noel, J.K. and Whitford, P.C.
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2019
Studying ribosome dynamics with simplified models.
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Methods 162-163
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1 June 2019
Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial.
Levin, J. and Maaß, S. and Schuberth, M. and Giese, A. and Oertel, W.H. and Poewe, W. and Trenkwalder, C. and Wenning, G.K. and Mansmann, U. and Südmeyer, M. and Eggert, K. and Mollenhauer, B. and Lipp, A. and Löhle, M. and Classen, J. and Münchau, A. and Kassubek, J. and Gandor, F. and Berg, D. and Egert-Schwender, S. and Eberhardt, C. and Paul, F. and Bötzel, K. and Ertl-Wagner, B. and Huppertz, H.J. and Ricard, I. and Höglinger, G.U.
Lancet Neurology 18
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August 2019
Mapping the MHC class I spliced immunopeptidome of cancer cells.
Liepe, J. and Sidney, J. and Lorenz, F.K.M. and Sette, A. and Mishto, M.
Cancer Immunology Research 7
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January 2019
Deubiquitinase USP10 regulates Notch signaling in the endothelium.
Lim, R. and Sugino, T. and Nolte, H. and Andrade, J. and Zimmermann, B. and Shi, C. and Doddaballapur, A. and Ong, Y.T. and Wilhelm, K. and Fasse, J.W.D. and Ernst, A. and Kaulich, M. and Husnjak, K. and Boettger, T. and Guenther, S. and Braun, T. and Krüger, M. and Benedito, R. and Dikic, I. and Potente, M.
Science 364
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12 April 2019
Angiotensin II type 2 receptor mediates high fat diet-induced cardiomyocyte hypertrophy and hypercholesterolemia.
Lima, V.M. and Lino, C.A. and Senger, N. and de Oliveira Silva, T. and Fonseca, R.I.B. and Bader, M. and Santos, R.A.S. and Júnior, JD. and Barreto-Chaves, M.L.M. and Diniz, G.P.
Molecular and Cellular Endocrinology 498
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1 December 2019
Unknown mutations and genotype/phenotype correlations of autosomal recessive congenital ichthyosis in patients from Saudi Arabia and Pakistan.
Lima Cunha, D. and Alakloby, O.M. and Gruber, R. and Kakar, N. and Ahmad, J. and Alawbathani, S. and Plank, R. and Eckl, K. and Krabichler, B. and Altmüller, J. and Nürnberg, P. and Zschocke, J. and Borck, G. and Schmuth, M. and Alabdulkareem, A.S. and Abdulaziz Alnutaifi, K. and Hennies, H.C.
Molecular Genetics & Genomic Medicine 7
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March 2019
Calcyphosine-like (CAPSL) is regulated in multiple symmetric lipomatosis and is involved in adipogenesis.
Lindner, A. and Marbach, F. and Tschernitz, S. and Ortner, C. and Berneburg, M. and Felthaus, O. and Prantl, L. and Kye, M.J. and Rappl, G. and Altmüller, J. and Thiele, H. and Schreml, S. and Schreml, J.
Scientific Reports 9
(1): 8444.
11 June 2019
Clinical relevance of circulating MACC1 and S100A4 transcripts for ovarian cancer.
Link, T. and Kuhlmann, J.D. and Kobelt, D. and Herrmann, P. and Vassileva, Y. and Kramer, M. and Frank, K. and Göckenjan, M. and Wimberger, P. and Stein, U.
Molecular Oncology 13
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May 2019
Endothelial B2-receptor overexpression as an alternative animal model for hereditary angioedema.
Lopes Veronez, C. and Maghsodi, S. and Todiras, M. and Popova, E. and Rodrigues, A.F. and Qadri, F. and Pesquero, J.B. and Bader, M.
Allergy 74
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October 2019
Sex-specific metabolic and functional differences in human umbilical vein endothelial cells from twin pairs.
Lorenz, M. and Blaschke, B. and Benn, A. and Hammer, E. and Witt, E. and Kirwan, J. and Fritsche-Guenther, R. and Gloaguen, Y. and Bartsch, C. and Vietzke, A. and Kramer, F. and Kappert, K. and Brunner, P. and Nguyen, H.G. and Dreger, H. and Stangl, K. and Knaus, P. and Stangl, V.
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Corrections of myocardial tissue sodium concentration measurements in human cardiac (23)Na MRI at 7 Tesla.
Lott, J. and Platt, T. and Niesporek, S.C. and Paech, D. and Behl, N.G.R. and Niendorf, T. and Bachert, P. and Ladd, M.E. and Nagel, A.M.
Magnetic Resonance in Medicine 82
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July 2019
Transcriptional states and chromatin accessibility underlying human erythropoiesis.
Ludwig, L.S. and Lareau, C.A. and Bao, E.L. and Nandakumar, S.K. and Muus, C. and Ulirsch, J.C. and Chowdhary, K. and Buenrostro, J.D. and Mohandas, N. and An, X. and Aryee, M.J. and Regev, A. and Sankaran, V.G.
Cell Reports 27
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11 June 2019
Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics.
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Cell 176
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7 March 2019
Genome-wide analysis of RNA and protein localization and local translation in mESC-derived neurons.
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Methods 162-163
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June 2019
Combined analysis of metabolomes, proteomes, and transcriptomes of hepatitis C virus-infected cells and liver to identify pathways associated with disease development.
Lupberger, J. and Croonenborghs, T. and Roca Suarez, A.A. and Van Renne, N. and Jühling, F. and Oudot, M.A. and Virzì, A. and Bandiera, S. and Jamey, C. and Meszaros, G. and Brumaru, D. and Mukherji, A. and Durand, S.C. and Heydmann, L. and Verrier, E.R. and El Saghire, H. and Hamdane, N. and Bartenschlager, R. and Fereshetian, S. and Ramberger, E. and Sinha, R. and Nabian, M. and Everaert, C. and Jovanovic, M. and Mertins, P. and Carr, S.A. and Chayama, K. and Dali-Youcef, N. and Ricci, R. and Bardeesy, N.M. and Fujiwara, N. and Gevaert, O. and Zeisel, M.B. and Hoshida, Y. and Pochet, N. and Baumert, T.F.
Gastroenterology 157
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August 2019
Prohibitin promotes dedifferentiation and is a potential therapeutic target in neuroblastoma.
MacArthur, I.C. and Bei, Y. and Garcia, H.D. and Ortiz, M.V. and Toedling, J. and Klironomos, F. and Rolff, J. and Eggert, A. and Schulte, J.H. and Kentsis, A. and Henssen, A.G.
JCI Insight 4
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16 May 2019
Microtubule cytoskeleton regulates connexin 43 localization and cardiac conduction in cardiomyopathy caused by mutation in A-type lamins gene.
Macquart, C. and Jüttner, R. and Le Dour, C. and Chatzifrangkeskou, M. and Schmitt, A. and Gotthardt, M. and Bonne, G. and Muchir, A.
Human Molecular Genetics 28
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15 December 2019
Genomic inversions and GOLGA core duplicons underlie disease instability at the 15q25 locus.
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PLoS Genetics 15
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27 March 2019
Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses.
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Scientific Reports 9
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23 December 2019
An integrated understanding of the molecular mechanisms how adipose tissue metabolism affects long-term body weight maintenance.
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1 January 2019
Structure-based screening of tetrazolylhydrazide inhibitors versus KDM4 histone demethylases.
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ChemMedChem 14
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6 November 2019
SorCS2 controls functional expression of amino acid transporter EAAT3 and protects neurons from oxidative stress and epilepsy-induced pathology.
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Cell Reports 26
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5 March 2019
Impact of stable angina on health status and quality of life perception of currently treated patients. The BRIDGE 2 survey.
Manolis, A.J. and Ambrosio, G. and Collins, P. and Dechend, R. and Lopez-Sendon, J. and Pegoraro, V. and Camm, A.J.
European Journal of Internal Medicine 70
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November 2019
The discovery of a LEMD2-associated nuclear envelopathy with early progeroid appearance suggests advanced applications for AI-driven facial phenotyping.
Marbach, F. and Rustad, C.F. and Riess, A. and Đukić, D. and Hsieh, T.C. and Jobani, I. and Prescott, T. and Bevot, A. and Erger, F. and Houge, G. and Redfors, M. and Altmueller, J. and Stokowy, T. and Gilissen, C. and Kubisch, C. and Scarano, E. and Mazzanti, L. and Fiskerstrand, T. and Krawitz, P.M. and Lessel, D. and Netzer, C.
American Journal of Human Genetics 104
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4 April 2019
A new highly thyrotropin receptor-selective small molecule antagonist with potential for the treatment of Graves' orbitopathy.
Marcinkowski, P. and Hoyer, I. and Specker, E. and Furkert, J. and Rutz, C. and Neuenschwander, M. and Sobottka, S. and Sun, H. and Nazare, M. and Berchner-Pfannschmidt, U. and von Kries, J.P. and Eckstein, A. and Schülein, R. and Krause, G.
Thyroid 29
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23 January 2019
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.
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Nature Communications 10
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18 December 2019
Evolution of replication origins in vertebrate genomes: rapid turnover despite selective constraints.
Massip, F. and Laurent, M. and Brossas, C. and Fernández-Justel, J.M. and Gómez, M. and Prioleau, M.N. and Duret, L. and Picard, F.
Nucleic Acids Research 47
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4 June 2019
Targeting APLN/APLNR improves antiangiogenic efficiency and blunts proinvasive side effects of VEGFA/VEGFR2 blockade in glioblastoma.
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Cancer Research 79
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May 2019
eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization.
Matthaeus, C. and Lian, X. and Kunz, S. and Lehmann, M. and Zhong, C. and Bernert, C. and Lahmann, I. and Müller, D.N. and Gollasch, M. and Daumke, O.
PLoS ONE 14
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10 October 2019
Targeted manipulation of brain serotonin: RNAi-mediated knockdown of tryptophan hydroxylase 2 in rats.
Matthes, S. and Mosienko, V. and Popova, E. and Rivalan, M. and Bader, M. and Alenina, N.
ACS Chemical Neuroscience 10
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17 July 2019
A gene expression atlas of embryonic neurogenesis in Drosophila reveals complex spatiotemporal regulation of lncRNAs.
McCorkindale, A.L. and Wahle, P. and Werner, S. and Jungreis, I. and Menzel, P. and Shukla, C.J. and Abreu, R.L.P. and Irizarry, R.A. and Meyer, I.M. and Kellis, M. and Zinzen, R.P.
Development 146
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28 March 2019
Long-term disability in neuromyelitis optica spectrum disorder with a history of myelitis is associated with age at onset, delay in diagnosis/preventive treatment, MRI lesion length and presence of symptomatic brain lesions.
Mealy, M.A. and Mossburg, S.E. and Kim, S.H. and Messina, S. and Borisow, N. and Lopez-Gonzalez, R. and Ospina, J.P. and Scheel, M. and Yeshokumar, A.K. and Awad, A. and Leite, M.I. and Arango, J.A.J. and Paul, F. and Palace, J. and Kim, H.J. and Levy, M.
Multiple Sclerosis and Related Disorders 28
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February 2019
Transcriptional dynamics of microRNAs and their targets during Drosophila neurogenesis.
Menzel, P. and McCorkindale, A.L. and Stefanov, S.R. and Zinzen, R.P. and Meyer, I.M.
RNA Biology 16
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20 January 2019
Targeted genomic integration of EGFP under tubulin beta 3 class III promoter and mEos2 under tryptophan hydroxylase 2 promoter does not produce sufficient levels of reporter gene expression.
Menzorov, A.G. and Orishchenko, K.E. and Fishman, V.S. and Shevtsova, A.A. and Mungalov, R.V. and Pristyazhnyuk, I.E. and Kizilova, E.A. and Matveeva, N.M. and Alenina, N. and Bader, M. and Rubtsov, N.B. and Serov, O.L.
Journal of Cellular Biochemistry 120
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October 2019
High-throughput screening for modulators of CFTR activity based on genetically engineered cystic fibrosis disease-specific iPSCs.
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Stem Cell Reports 12
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11 June 2019
Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.
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Nature 566
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7 February 2019
Little Old Ladies' Eye.
Middeke, M. and Nasemann, J. and Luft, F.C.
Artery Research
June 2019
Microbial abundance, activity and population genomic profiling with mOTUs2.
Milanese, A. and Mende, D.R. and Paoli, L. and Salazar, G. and Ruscheweyh, H.J. and Cuenca, M. and Hingamp, P. and Alves, R. and Costea, P.I. and Coelho, L.P. and Schmidt, T.S.B. and Almeida, A. and Mitchell, A.L. and Finn, R.D. and Huerta-Cepas, J. and Bork, P. and Zeller, G. and Sunagawa, S.
Nature Communications 10
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4 March 2019
Application of europium-doped very small iron oxide nanoparticles to visualize neuroinflammation with MRI and fluorescence microscopy.
Millward, J.M. and de Schellenberger, A.A. and Berndt, D. and Hanke-Vela, L. and Schellenberger, E. and Waiczies, S. and Taupitz, M. and Kobayashi, Y. and Wagner, S. and Infante-Duarte, C.
Neuroscience 403
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1 April 2019
Assessment of disease progression in dysferlinopathy: a 1-year cohort study.
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Neurology 92
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29 January 2019
Autosomal-recessive mutations in MESD cause osteogenesis imperfecta.
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American Journal of Human Genetics 105
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3 October 2019
240th ENMC workshop: The involvement of skeletal muscle stem cells in the pathology of muscular dystrophies 25–27 January 2019, Hoofddorp, The Netherlands.
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Neuromuscular Disorders 29
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2019
Insights into pancreatic β cell energy metabolism using rodent β cell models.
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Wellcome Open Research 2
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25 September 2019
Characterization of mouse adult testicular macrophage populations by immunofluorescence imaging and flow cytometry.
Mossadegh-Keller, N. and Sieweke, M.H.
Bio-protocol 9
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5 March 2019
Normative data and minimally detectable change for inner retinal layer thicknesses using a semi-automated OCT image segmentation pipeline.
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November 2019
Proteomic and transcriptomic changes in hibernating grizzly bears reveal metabolic and signaling pathways that protect against muscle atrophy.
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Scientific Reports 9
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27 December 2019
Deciphering human ribonucleoprotein regulatory networks.
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Nucleic Acids Research 47
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25 January 2019
Mutations in PIGB cause an inherited GPI biosynthesis defect with an axonal neuropathy and metabolic abnormality in severe cases.
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1 August 2019
A multiple Piccolino-RIBEYE interaction supports plate-shaped synaptic ribbons in retinal neurons.
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Journal of Neuroscience 39
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3 April 2019
The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
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Aging Cell 18
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December 2019
Current clinical practice and challenges in the management of secondary immunodeficiency in hematological malignancies.
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European Journal of Haematology 102
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June 2019
Magnetic resonance perfusion or fractional flow reserve in coronary disease.
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New England Journal of Medicine 380
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20 June 2019
Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.
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eLife 8
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9 May 2019
Fluorescent labeling of CRISPR/Cas9 RNP for gene knockout in HSPCs and iPSCs reveals an essential role for GADD45b in stress response.
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Blood Advances 3
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8 January 2019
Distinct subgroups in hypertrophic cardiomyopathy in the NHLBI HCM Registry.
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Journal of the American College of Cardiology 74
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12 November 2019
HIF1A and NFAT5 coordinate Na(+)-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.
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Autophagy 15
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November 2019
Assessment of genetic variant burden in epilepsy-associated brain lesions.
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European Journal of Human Genetics 27
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November 2019
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
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Nature Communications 10
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29 March 2019
Gene expression cartography.
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Nature 576
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5 December 2019
Polymer-like model to study the dynamics of dynamin filaments on deformable membrane tubes.
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Biophysical Journal 117
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19 November 2019
Optimal intereye difference thresholds by optical coherence tomography in multiple sclerosis: an international study.
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Annals of Neurology 85
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Placental CX3CL1 is deregulated by angiotensin II and contributes to a pro-inflammatory trophoblast-monocyte interaction.
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2 February 2019
DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.
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Journal of Cell Science 132
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Characterization of bacterial communities in wastewater with enhanced taxonomic resolution by full-length 16S rRNA sequencing.
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Scientific Reports 9
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4 July 2019
Age-related gliosis promotes central nervous system lymphoma through CCL19-mediated tumor cell retention.
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Optical coherence tomography in myelin-oligodendrocyte-glycoprotein antibody-seropositive patients: a longitudinal study.
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Journal of Neuroinflammation 16
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25 July 2019
Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study.
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Journal of Neuroinflammation 16
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11 March 2019
Genetic deletion of the alamandine receptor MrgD leads to dilated cardiomyopathy in mice.
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American Journal of Physiology Heart and Circulatory Physiology 316
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January 2019
Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.
Omar, F. and Findlay, J.E. and Carfray, G. and Allcock, R.W. and Jiang, Z. and Moore, C. and Muir, A.L. and Lannoy, M. and Fertig, B.A. and Mai, D. and Day, J.P. and Bolger, G. and Baillie, G.S. and Schwiebert, E. and Klussmann, E. and Pyne, N.J. and Ong, A.C.M. and Bowers, K. and Adam, J.M. and Adams, D.R. and Houslay, M.D. and Henderson, D.J.P.
Proceedings of the National Academy of Sciences of the United States of America 116
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Calcium-independent exo-endocytosis coupling at small central synapses.
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Cell Reports 29
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17 December 2019
Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor.
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JCI Insight 4
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8 August 2019
Low-density granulocytes are a novel immunopathological feature in both multiple sclerosis and neuromyelitis optica spectrum disorder.
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Frontiers in Immunology 10
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Preformed chromatin topology assists transcriptional robustness of Shh during limb development.
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18 June 2019
Damage of the lateral geniculate nucleus in MS: assessing the missing node of the visual pathway.
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7 May 2019
Attack-related damage of thalamic nuclei in neuromyelitis optica spectrum disorders.
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Quantitative 7T MRI does not detect occult brain damage in neuromyelitis optica.
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Flammer syndrome and autoimmune inflammatory conditions of the central nervous system: multifactorial interrelations.
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Homozygosity for the c.428delG variant in KIAA0586 in a healthy individual: implications for molecular testing in patients with Joubert syndrome.
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April 2019
Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancer.
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Domainoid: domain-oriented orthology inference.
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BMC Bioinformatics 20
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Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles.
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1 November 2019
Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis.
Pfuhl, C. and Grittner, U. and Gieß, R.M. and Scheel, M. and Behrens, J.R. and Rasche, L. and Pache, F.C. and Wenzel, R. and Brandt, A.U. and Bellmann-Strobl, J. and Paul, F. and Ruprecht, K. and Oechtering, J.
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8 October 2019
Small-molecule lysophosphatidic acid receptor 5 (LPAR5) antagonists: versatile pharmacological tools to regulate inflammatory signaling in BV-2 microglia cells.
Plastira, I. and Joshi, L. and Bernhart, E. and Schoene, J. and Specker, E. and Nazare, M. and Sattler, W.
Frontiers in Cellular Neuroscience 13
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29 December 2019
Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression.
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2 January 2019
Biallelic mutation of human SLC6A6 encoding the taurine transporter TAUT is linked to early retinal degeneration.
Preising, M.N. and Görg, B. and Friedburg, C. and Qvartskhava, N. and Budde, B.S. and Bonus, M. and Toliat, M.R. and Pfleger, C. and Altmüller, J. and Herebian, D. and Beyer, M. and Zöllner, H.J. and Wittsack, H.J. and Schaper, J. and Klee, D. and Zechner, U. and Nürnberg, P. and Schipper, J. and Schnitzler, A. and Gohlke, H. and Lorenz, B. and Häussinger, D. and Bolz, H.J.
FASEB Journal 33
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October 2019
Pain-prescription differences - an analysis of 500,000 discharge summaries.
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Long-term effects of Na(+)/Ca(2+) exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction.
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European Journal of Heart Failure 21
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December 2019
Toward (19)F magnetic resonance thermometry: spin-lattice and spin-spin-relaxation times and temperature dependence of fluorinated drugs at 9.4 T.
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Magnetic Resonance Materials in Physics Biology and Medicine 32
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February 2019
Linkage evidence for a two-locus inheritance of LQT-associated seizures in a multigenerational LQT family with a novel KCNQ1 loss-of-function mutation.
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Frontiers in Neurology 10
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June 2019
Comparison of zebrafish and mice knockouts for Megalencephalic Leukoencephalopathy proteins indicates that GlialCAM/MLC1 forms a functional unit.
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21 November 2019
KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells.
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Acta Pharmacologica Sinica 40
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April 2019
Functional identity of hypothalamic melanocortin neurons depends on Tbx3.
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Nature Metabolism 1
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Deleting full length titin versus the titin M-band region leads to differential mechanosignaling and cardiac phenotypes.
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Interaction of pregnancy-specific glycoprotein 1 with integrin Α5β1 is a modulator of extravillous trophoblast functions.
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Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self-renewal and identity.
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1 October 2019
Anoctamin-4 is a bona fide Ca(2+)-dependent non-selective cation channel.
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19 February 2019
Sugars make the difference - Glycosylation of cardiodepressant antibodies regulates their activity in dilated cardiomyopathy.
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Next-generation sequencing of 32 genes associated with hereditary aortopathies and related disorders of connective tissue in a cohort of 199 patients.
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Porous medium 3D flow simulation of contrast media washout in cardiac MRI reflects myocardial injury.
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August 2019
Clonality of circulating tumor cells in breast cancer brain metastasis patients.
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3 September 2019
Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.
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Disentangling genetic and environmental effects on the proteotypes of individuals.
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The central nervous system contains ILC1s that differ from NK cells in the response to inflammation.
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Association of dietary intake of milk and dairy products with blood concentrations of insulin-like growth factor 1 (IGF-1) in Bavarian adults.
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Evaluation of colorectal cancer subtypes and cell lines using deep learning.
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Tissue sodium content and arterial hypertension in obese adolescents.
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Resolving titin's lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes.
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Novel calcineurin A (PPP3CA) variant associated with epilepsy, constitutive enzyme activation and downregulation of protein expression.
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Measurable residual disease monitoring in acute myeloid leukemia with t(8;21)(q22;q22.1): results from the AML Study Group.
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Serotonin synthesis protects the mouse colonic crypt from DNA damage and colorectal tumorigenesis.
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Gene expression changes and community turnover differentially shape the global ocean metatranscriptome.
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Electrophysiological and molecular characterization of the parasubiculum.
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Advantages and challenges of cardiovascular and lymphatic studies in zebrafish research.
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Evaluation of the central vein sign as a diagnostic imaging biomarker in multiple sclerosis.
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Proteogenomic analysis of human colon cancer reveals new therapeutic opportunities.
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Association of a PD-L2 gene polymorphism with chronic lymphatic filariasis in a South Indian cohort.
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Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart.
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Canonical BMP signaling in tubular cells mediates recovery after acute kidney injury.
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Fibroblast primary cilia are required for cardiac fibrosis.
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Human sFLT1 leads to severe changes in placental differentiation and vascularization in a transgenic hsFLT1/rtTA FGR mouse model.
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The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma.
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Efficacy of high-frequency repetitive transcranial magnetic stimulation in schizophrenia patients with treatment-resistant negative symptoms treated with clozapine.
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De novo mutations in FOXJ1 result in a motile ciliopathy with hydrocephalus and randomization of left/right body asymmetry.
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Increased retention of gadolinium in the inflamed brain after repeated administration of gadopentetate dimeglumine: a proof-of-concept study in mice combining ICP-MS and micro- and nano-SR-XRF.
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The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats.
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Germline loss-of-function variants in the BARD1 gene are associated with early-onset familial breast cancer but not ovarian cancer.
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Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.
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Spatially restricted stromal Wnt signaling restrains prostate epithelial progenitor growth through direct and indirect mechanisms.
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Health-related quality of life and neurocognitive functioning with lomustine-temozolomide versus temozolomide in patients with newly diagnosed, MGMT-methylated glioblastoma (CeTeG/NOA-09): a randomised, multicentre, open-label, phase 3 trial.
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Global identification of functional microRNA-mRNA interactions in Drosophila.
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Distinct genetic alterations and luminal molecular subtype in nested variant of urothelial carcinoma (NVUC).
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Neural mechanisms of perceptual decision-making and their link to neuropsychiatric symptoms in multiple sclerosis.
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Interactions between neural decision-making circuits predict long-term dietary treatment success in obesity.
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Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis.
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High salt inhibits tumor growth by enhancing anti-tumor immunity.
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Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer.
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Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)-study protocol for a randomized controlled trial.
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PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells.
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September 2019
The Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer.
Zhu, Q. and Fang, L. and Heuberger, J. and Kranz, A. and Schipper, J. and Scheckenbach, K. and Oliveira Vidal, R. and Sunaga-Franze, D.Y. and Müller, M. and Wulf-Goldenberg, A. and Sauer, S. and Birchmeier, W.
Cell Reports 26
(2): 415-428.
8 January 2019
Physical activity during adolescence and risk of colorectal adenoma later in life: results from the Nurses' Health Study II.
de Rezende, L.F.M. and Lee, D.H. and Keum, N.N. and Nimptsch, K. and Song, M. and Lee, I.M. and Eluf-Neto, J. and Ogino, S. and Fuchs, C. and Meyerhardt, J. and Chan, A.T. and Willett, W. and Giovannucci, E. and Wu, K.
British Journal of Cancer 121
(1): 86-94.
July 2019
Diffusion-weighted renal MRI at 9.4 Tesla using RARE to improve anatomical integrity.
dos Santos Periquito, J. and Paul, K. and Huelnhagen, T. and Ku, M.C. and Ji, Y. and Cantow, K. and Gladytz, T. and Grosenick, D. and Flemming, B. and Seeliger, E. and Waiczies, S. and Niendorf, T. and Pohlmann, A.
Scientific Reports 9
(1): 19723.
23 December 2019
The translational landscape of the human heart.
van Heesch, S. and Witte, F. and Schneider-Lunitz, V. and Schulz, J.F. and Adami, E. and Faber, A. and Kirchner, M. and Maatz, H. and Blachut, S. and Sandmann, C.L. and Kanda, M. and Worth, C.L. and Schafer, S. and Calviello, L. and Merriott, R. and Patone, G. and Hummel, O. and Wyler, E. and Obermayer, B. and Mücke, M. and Lindberg, E.L. and Trnka, F. and Memczak, S. and Schilling, M. and Felkin, L.E. and Barton, P.J.R. and Quaife, N.M. and Vanezis, K. and Diecke, S. and Mukai, M. and Mah, N. and Oh, S.J. and Kurtz, A. and Schramm, C. and Schwinge, D. and Sebode, M. and Harakalova, M. and Asselbergs, F.W. and Vink, A. and de Weger, R.A. and Viswanathan, S. and Widjaja, A.A. and Gärtner-Rommel, A. and Milting, H. and Dos Remedios, C. and Knosalla, C. and Mertins, P. and Landthaler, M. and Vingron, M. and Linke, W.A. and Seidman, J.G. and Seidman, C.E. and Rajewsky, N. and Ohler, U. and Cook, S.A. and Hubner, N.
Cell 178
(1): 242-260.
27 June 2019
Lack of brain serotonin affects feeding and differentiation of newborn cells in the adult hypothalamus.
van Lingen, M. and Sidorova, M. and Alenina, N. and Klempin, F.
Frontiers in Cell and Developmental Biology 7
: 65.
April 2019
Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L. and Kärgel, E. and Franke, V. and McShane, E. and Schulz-Beiss, K.W. and Patone, G. and Schleussner, N. and Kolesnichenko, M. and Hübner, N. and Daumke, O. and Selbach, M. and Akalin, A. and Mathas, S. and Scheidereit, C.
Blood 133
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28 March 2019
Empfehlungen zu kardialen MRT-Untersuchungen bei Patienten mit Herzschrittmachern und implantierbaren Kardioverter-Defibrillatoren [Recommendations for cardiac magnetic resonance imaging in patients with cardiac pacemakers andimplantable cardioverter defibrillators].
von Knobelsdorff-Brenkenhoff, F. and Bauer, W.R. and Deneke, T. and Fleck, E. and Rolf, A. and Schulz-Menger, J. and Sommer, P. and Tillmanns, C. and Eitel, I.
Kardiologe 13
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April 2019
Book Section
Genetic models.
Alenina, N. and Bader, M.
In:
Angiotensin-(1-7) : a comprehensive review.
Springer, Cham, 35-51.
ISBN 978-3-030-22695-4
2019
The genetic landscape of cardiomyopathies.
Gerull, B. and Klaassen, S. and Brodehl, A.
In:
Genetic Causes of Cardiac Disease.
Cardiac and Vascular Biology, 7
(7).
Springer, Cham, 45-91.
ISBN 978-3-030-27370-5
28 November 2019
Systems biology approach to study cancer metabolism.
Kempa, S. and Royla, N.
In:
Encyclopedia of Cancer.
Elsevier / Academic Press, 426-428.
ISBN 978-0-12-812485-7
2019
Human cardiac magnetic resonance at ultrahigh fields : technical innovations, early clinical applications and opportunities for discoveries.
Niendorf, T. and Huelnhagen, T. and Winter, L. and Paul, K.
In:
Cardiovascular magnetic resonance : a companion to Braunwald's heart disease.
Elsevier, Philadelphia, PA, 142-160.
ISBN 978-0-323-41561-3
2019
Multiple sclerosis.
Veauthier, C. and Paul, F.
In:
Handbook of Sleep Disorders in Medical Conditions.
Elsevier / Academic Press, 345-369.
ISBN 978-0-12-813014-8
2019
Conference or Workshop Item
All-in-one confocal and widefield fluorescence microscope to investigate membrane receptor dynamics.
Bathe-Peters, M. and Gmach, P. and Annibale, P. and Lohse, M.J.
In: Imaging and Applied Optics Congress 2019 (COSI, IS, MATH, pcAOP), 24-27 Jun 2019, Munich, Germany.
2019
Simultaneous SPECT/MR imaging with a SiPM-based preclinical insert.
Carminati, M. and Baratelli, F.M. and Massara, M. and Occhipinti, M. and Nagy, K. and Nyitrai, Z. and Czeller, M. and Kühne, A. and Niendorf, T. and Valtorta, S. and Belloli, S. and Moresco, R.M. and Savi, A. and Iadanza, A. and Falini, A. and Politi, L.S. and Cadioli, M. and Fiorini, C.
In: 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference Proceedings (NSS/MIC), 10-17 Nov 2018, Sydney, NSW, Australia.
5 September 2019
Towards depth-resolved characterization of hemodynamics and oxygenation in the rat kidney.
Gladytz, T. and Cantow, K. and Flemming, B. and Pohlmann, A. and Niendorf, T. and Seeliger, E. and Grosenick, D.
In: SPIE-OSA 2019, 23-25 Jun 2019, Munich, Germany.
2019
Near infrared spectroscopy system for quantitative monitoring of renal hemodynamics and oxygenation in rats.
Gladytz, T. and Hoppe, A. and Cantow, K. and Flemming, B. and Pohlmann, A. and Niendorf, T. and Seeliger, E. and Grosenick, D.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
1 March 2019
Nanocapsule induced morphology and migration changes in single cell layers quantified with digital holographic microscopy.
Kaiser, M. and Pohl, L. and Ketelhut, S. and Kastl, L. and Gorzelanny, C. and Götte, M. and Schnekenburger, J. and Goycoolea, F.M. and Kemper, B.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
4 March 2019
Mathematical modeling of semiconductors: from quantum mechanics to devices.
Kantner, M. and Mielke, A. and Mittnenzweig, M. and Rotundo, N.
In: Joint CIM-WIAS Workshop, TAAO 2017, 6-8 Dec 2017, Lisbon, Portugal.
28 November 2019
Automatic quality evaluation as assessment standard for optical coherence tomography.
Kauer, J. and Gawlik, K. and Zimmermann, H.G. and Kadas, E.M. and Bereuter, C. and Paul, F. and Brandt, A.U. and Hausser, F. and Beckers, I.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, United States.
26 February 2019
Quantitative phase imaging-based concepts for the analysis of global morphology changes in confluent cell layers.
Kemper, B. and Pohl, L. and Kaiser, M. and Doepker, E. and Schnekenburger, J. and Ketelhut, S.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
4 March 2019
Label-free detection of global morphology changes in confluent cell layers utilizing quantitative phase imaging with digital holographic microscopy.
Kemper, B. and Pohl, L. and Kaiser, M. and Döpker, E. and Schnekenburger, J. and Ketelhut, S.
In: European Conferences on Biomedical Optics 2019, 26-27 Jun 2019, Munich, Germany.
22 July 2019
Development of a backward-mode photoacoustic microscope using a Fabry-Pérot sensor.
Pohle, U. and Baumann, E. and Pulwer, S. and Villringer, C. and Zhang, E.Z. and Gerhardt, H. and Laufer, J.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
6 March 2019
Fast alignment of limited angle tomograms by projected cross correlation.
Sanchez, R.M. and Mester, R. and Kudryashev, M.
In: 2019 27th European Signal Processing Conference (EUSIPCO), 2-6 Sep 2019, A Coruna, Spain.
18 November 2019
A federated in-memory database system for life sciences.
Schapranow, M.P. and Perscheid, C. and Wachsmann, A. and Siegert, M. and Bock, C. and Horschig, F. and Liedke, F. and Brauer, J. and Plattner, H.
In: 9th, 10th, 11th International Workshop on Business Intelligence for the Real-Time Enterprise, BIRTE 2015, BIRTE 2016, BIRTE 2017; International Conference on Very Large Data Bases, VLDB 2017, 28 Aug - 1 Sep 2017, Munich, Germany.
2019
A convex relaxation for multi-graph matching.
Swoboda, P. and Kainmüller, D. and Mokarian, A. and Theobalt, C. and Bernard, F.
In: 2019 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 16-20 Jun 2019, Long Beach, CA, USA.
2019
Functional LGE imaging: cardiac phase-resolved assessment of focal fibrosis.
Weingartner, S. and Demirel, O.B. and Shenoy, C. and Schad, L.R. and Schulz-Menger, J. and Akcakaya, M.
In: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 23-27 Jul 2019, Berlin, Germany.
2019
Review
Pressurized intraperitoneal aerosol chemotherapy and its effect on gastric-cancer-derived peritoneal metastases: an overview.
Alberto, M. and Brandl, A. and Garg, P.K. and Gül-Klein, S. and Dahlmann, M. and Stein, U. and Rau, B.
Clinical and Experimental Metastasis 36
(1): 1-14.
February 2019
Biological determinants of physical activity across the life course: a "Determinants of Diet and Physical Activity" (DEDIPAC) umbrella systematic literature review.
Aleksovska, K. and Puggina, A. and Giraldi, L. and Buck, C. and Burns, C. and Cardon, G. and Carlin, A. and Chantal, S. and Ciarapica, D. and Colotto, M. and Condello, G. and Coppinger, T. and Cortis, C. and D'Haese, S. and De Craemer, M. and Di Blasio, A. and Hansen, S. and Iacoviello, L. and Issartel, J. and Izzicupo, P. and Jaeschke, L. and Kanning, M. and Kennedy, A. and Ling, F. and Luzak, A. and Napolitano, G. and Nazare, J.A. and Perchoux, C. and Pischon, T. and Polito, A. and Sannella, A. and Schulz, H. and Sohun, R. and Steinbrecher, A. and Schlicht, W. and Ricciardi, W. and MacDonncha, C. and Capranica, L. and Boccia, S.
Sports Medicine - Open 5
(1): 2.
8 January 2019
StaBle angina: peRceptIon of neeDs, quality of life and manaGemEnt of patients (BRIDGE study) - a multinational European physician survey.
Ambrosio, G. and Collins, P. and Dechend, R. and Lopez-Sendon, J. and Manolis, A.J. and Camm, A.J.
Angiology 70
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1 May 2019
Serotonylation: serotonin signaling and epigenetics.
Bader, M.
Frontiers in Molecular Neuroscience 12
: 288.
21 November 2019
Small molecules for modulating the localisation of the water channel aquaporin-2-disease relevance and perspectives for targeting local cAMP signalling.
Baltzer, S. and Klussmann, E.
Naunyn-Schmiedeberg's Archives of Pharmacology 392
(9): 1049-1064.
September 2019
Pregnancy galectinology: insights into a complex network of glycan binding proteins.
Blois, S.M. and Dveksler, G. and Vasta, G.R. and Freitag, N. and Blanchard, V. and Barrientos, G.
Frontiers in Immunology 10
: 1166.
May 2019
Light-microscopy methods in C. elegans research.
Breimann, L. and Preusser, F. and Preibisch, S.
Current Opinion in Systems Biology 13
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February 2019
Mesothelial-mesenchymal transitions in embryogenesis.
Carmona, R. and Ariza, L. and Cano, E. and Jiménez-Navarro, M. and Muñoz-Chápuli, R.
Seminars in Cell & Developmental Biology 92
: 37-44.
August 2019
Integrative approaches in structural biology: a more complete picture from the combination of individual techniques.
Cerofolini, L. and Fragai, M. and Ravera, E. and Diebolder, C.A. and Renault, L. and Calderone, V.
Biomolecules 9
(8): 370.
14 August 2019
Current and future treatment strategies for rhabdomyosarcoma.
Chen, C. and Dorado-Garcia, H. and Scheer, M. and Henssen, A.G.
Frontiers in Oncology 9
: 1458.
20 December 2019
Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders.
Ciccarelli, O. and Cohen, J.A. and Reingold, S.C. and Weinshenker, B.G.
Lancet Neurology 18
(2): 185-197.
February 2019
Autophagy in the renewal, differentiation and homeostasis of immune cells.
Clarke, A.J. and Simon, A.K.
Nature Reviews Immunology 19
(3): 170-183.
March 2019
Pancreas organogenesis: the interplay between surrounding microenvironment(s) and epithelium-intrinsic factors.
Cozzitorto, C. and Spagnoli, F.M.
Current Topics in Developmental Biology 132
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2019
Akutes pulmorenales Syndrom auf der Intensivstation: Rationale Diagnostik und Therapie [Acute pulmonary-renal syndrome in the intensive care unit: rational diagnostics and treatment].
Enghard, P. and Erley, C. and Schreiber, A.
Nephrologe 14
: 438-445.
2 October 2019
Role of Zeb2/Sip1 in neuronal development.
Epifanova, E. and Babaev, A. and Newman, A.G. and Tarabykin, V.
Brain Research 1705
: 24-31.
15 February 2019
Elementary calcium signaling in arterial smooth muscle.
Fan, G. and Cui, Y. and Gollasch, M. and Kassmann, M.
Channels 13
(1): 505-519.
4 December 2019
Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines.
Filippi, M. and Preziosa, P. and Banwell, B.L. and Barkhof, F. and Ciccarelli, O. and De Stefano, N. and Geurts, J.J.G. and Paul, F. and Reich, D.S. and Toosy, A.T. and Traboulsee, A. and Wattjes, M.P. and Yousry, T.A. and Gass, A. and Lubetzki, C. and Weinshenker, B.G. and Rocca, M.A.
Brain 142
(7): 1858-1875.
July 2019
The role of Wnt and R-spondin in the stomach during health and disease.
Fischer, A.S. and Sigal, M.
Biomedicines 7
(2): 44.
19 June 2019
Human stem cell models: lessons for pancreatic development and disease.
Gaertner, B. and Carrano, A.C. and Sander, M.
Genes & Development 33
(21-22): 1475-1490.
1 November 2019
Suggestions for improving the design of clinical trials in multiple sclerosis - results of a systematic analysis of completed phase III trials.
Gehr, S. and Kaiser, T. and Kreutz, R. and Ludwig, W.D. and Paul, F.
EPMA Journal 10
(4): 425-436.
December 2019
Were our critics right about the Stasi? AIDS disinformation and "disinformation squared" after five years.
Geissler, E. and Sprinkle, R.H.
Politics and the Life Sciences 38
(1): 32-61.
2019
Advances and applications in the quest for orthologs.
Glover, N. and Dessimoz, C. and Ebersberger, I. and Forslund, S.K. and Gabaldón, T. and Huerta-Cepas, J. and Martin, M.J. and Muffato, M. and Patricio, M. and Pereira, C. and Sousa da Silva, A. and Wang, Y. and Sonnhammer, E. and Thomas, P.D.
Molecular Biology and Evolution 36
(10): 2157-2164.
October 2019
Sex differences in autoimmune disorders of the central nervous system.
Gold, S.M. and Willing, A. and Leypoldt, F. and Paul, F. and Friese, M.A.
Seminars in Immunopathology 41
(2): 177-188.
March 2019
Cellular senescence: defining a path forward.
Gorgoulis, V. and Adams, P.D. and Alimonti, A. and Bennett, D.C. and Bischof, O. and Bishop, C. and Campisi, J. and Collado, M. and Evangelou, K. and Ferbeyre, G. and Gil, J. and Hara, E. and Krizhanovsky, V. and Jurk, D. and Maier, A.B. and Narita, M. and Niedernhofer, L. and Passos, J.F. and Robbins, P.D. and Schmitt, C.A. and Sedivy, J. and Vougas, K. and von Zglinicki, T. and Zhou, D. and Serrano, M. and Demaria, M.
Cell 179
(4): 813-827.
31 October 2019
Microglia/brain macrophages as central drivers of brain tumor pathobiology.
Gutmann, D.H. and Kettenmann, H.
Neuron 104
(3): 442-449.
6 November 2019
Sodium chloride triggers Th17 mediated autoimmunity.
Haase, S. and Wilck, N. and Kleinewietfeld, M. and Müller, D.N. and Linker, R.A.
Journal of Neuroimmunology 329
: 9-13.
15 April 2019
Structural features of tight-junction proteins.
Heinemann, U. and Schuetz, A.
International Journal of Molecular Sciences 20
(23): 6020.
29 November 2019
Context-dependent signaling of CXC chemokine receptor 4
and atypical chemokine receptor 3.
Heuninck, J. and Perpina Viciano, C. and Işbilir, A. and Caspar, B. and Capoferri, D. and Briddon, S.J. and Durroux, T. and Hill, S.J. and Lohse, M.J. and Milligan, G. and Pin, J.P. and Hoffmann, C.
Molecular Pharmacology 96
(6): 778-793.
December 2019
Targeting the tumor microenvironment of leukemia and lymphoma.
Höpken, U.E. and Rehm, A.
Trends in Cancer 5
(6): 351-364.
June 2019
Live-imaging readouts and cell models for phenotypic profiling of mitochondrial function.
Iannetti, E.F. and Prigione, A. and Smeitink, J.A.M. and Koopman, W.J.H. and Beyrath, J. and Renkema, H.
Frontiers in Genetics 10
: 131.
March 2019
Cardiovascular programming during and after diabetic pregnancy: role of placental dysfunction and IUGR.
Langmia, I.M. and Kräker, K. and Weiss, S.E. and Haase, N. and Schütte, T. and Herse, F. and Dechend, R.
Frontiers in Endocrinology 10
: 215.
April 2019
Allergy and atopy from infancy to adulthood: messages from the German birth cohort MAS.
Lau, S. and Matricardi, P.M. and Wahn, U. and Lee, Y.A. and Keil, T.
Annals of Allergy, Asthma & Immunology 122
(1): 25-32.
January 2019
The dynamic nature of senescence in cancer.
Lee, S. and Schmitt, C.A.
Nature Cell Biology 21
(1): 94-101.
January 2019
Schwere Azidose: Differenzialdiagnostik und Therapie [Severe acidosis: differential diagnostics and treatment].
Lehner, L.J. and Oppert, M. and Kettritz, R.
Nephrologe 14
(6): 431-437.
November 2019
Subtomogram averaging from cryo-electron tomograms.
Leigh, K.E. and Navarro, P.P. and Scaramuzza, S. and Chen, W. and Zhang, Y. and Castaño-Díez, D. and Kudryashev, M.
Methods in Cell Biology 152
: 217-259.
2019
Pathophysiological role of caveolae in hypertension.
Lian, X. and Matthaeus, C. and Kaßmann, M. and Daumke, O. and Gollasch, M.
Frontiers in Medicine 6
: 153.
July 2019
The role of 17β-estradiol and estrogen receptors in regulation of Ca(2+) channels and mitochondrial function in cardiomyocytes.
Mahmoodzadeh, S. and Dworatzek, E.
Frontiers in Endocrinology 10
: 310.
May 2019
Excitatory amino acid transporters in physiology and disorders of the central nervous system.
Malik, A.R. and Willnow, T.E.
International Journal of Molecular Sciences 20
(22): 5671.
12 November 2019
A (3D-nuclear) space odyssey: making sense of Hi-C maps.
Mota-Gómez, I. and Lupiáñez, D.G.
Genes 10
(6): 415.
29 May 2019
Sodium in the microenvironment regulates immune responses and tissue homeostasis.
Müller, D.N. and Wilck, N. and Haase, S. and Kleinewietfeld, M. and Linker, R.A.
Nature Reviews Immunology 19
(4): 243-254.
April 2019
Elektromagnetische Interferenz von aktiven Herzrhythmusimplantaten im Alltag und im beruflichen Umfeld: Stellungnahme der Deutschen Gesellschaft für Kardiologie (DGK) und der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin (DGAUM) [Electromagnetic interference of active cardiac rhythm implants in the daily routine and occupational environment: statement of the German Cardiac Society (DGK) and the German Society for Occupational and Environmental Medicine (DGAUM)].
Napp, A. and Kolb, C. and Lennerz, C. and Bauer, W. and Schulz-Menger, J. and Kraus, T. and Marx, N. and Stunder, D.
Kardiologe 13
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August 2019
Interplay of Na(+) balance and immunobiology of dendritic cells.
Neubert, P. and Schröder, A. and Müller, D.N. and Jantsch, J.
Frontiers in Immunology 10
: 599.
March 2019
Diagnosis of obesity and use of obesity biomarkers in science and clinical medicine.
Nimptsch, K. and Konigorski, S. and Pischon, T.
Metabolism 92
: 61-70.
March 2019
SHP-2 in lymphocytes' cytokine and inhibitory receptor signaling.
Niogret, C. and Birchmeier, W. and Guarda, G.
Frontiers in Immunology 10
: 2468.
25 October 2019
Cognitive impairment in neuromyelitis optica spectrum disorders: a review of clinical and neuroradiological features.
Oertel, F.C. and Schließeit, J. and Brandt, A.U. and Paul, F.
Frontiers in Neurology 10
: 608.
12 June 2019
Novel uses of retinal imaging with optical coherence tomography in multiple sclerosis.
Oertel, F.C. and Zimmermann, H.G. and Brandt, A.U. and Paul, F.
Expert Review of Neurotherapeutics 19
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2 January 2019
Strategies for in vivo reprogramming.
Ofenbauer, A. and Tursun, B.
Current Opinion in Cell Biology 61
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December 2019
The cortical states of wakefulness.
Poulet, J.F.A. and Crochet, S.
Frontiers in Systems Neuroscience 12
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January 2019
Regulatory landscaping: how enhancer-promoter communication is sculpted in 3D.
Robson, M.I. and Ringel, A.R. and Mundlos, S.
Molecular Cell 74
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20 June 2019
The renin-angiotensin system: going beyond the classical paradigms.
Santos, R.A.S. and Oudit, G.Y. and Verano-Braga, T. and Canta, G. and Steckelings, U.M. and Bader, M.
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May 2019
Cien años de microglía: milestones in a century of microglial research.
Sierra, A. and Paolicelli, R.C. and Kettenmann, H.
Trends in Neurosciences 42
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November 2019
Molecular mechanisms of kidney injury and repair in arterial hypertension.
Sievers, L.K. and Eckardt, K.U.
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30 April 2019
Deconstructing age reprogramming.
Singh, P.B. and Laktionov, P.P. and Newman, A.G.
Journal of Biosciences 44
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September 2019
The Pediatric Cell Atlas: defining the growth phase of human development at single-cell resolution.
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Developmental Cell 49
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8 April 2019
Applying synergy metrics to oncology combination screening data: agreements, disagreements and pitfalls.
Vlot, A.H.C. and Aniceto, N. and Menden, M.P. and Ulrich-Merzenich, G. and Bender, A.
Drug Discovery Today 24
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December 2019
The pathobiology of perturbed mutant huntingtin protein-protein interactions in Huntington's disease.
Wanker, E.E. and Ast, A. and Schindler, F. and Trepte, P. and Schnoegl, S.
Journal of Neurochemistry 151
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November 2019
3D organ models-Revolution in pharmacological research?
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Endothelial metabolism - more complex (III) than previously thought.
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A helminth chitinase structurally similar to mammalian chitinase displays immunomodulatory properties.
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25 February 2019
Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC.
Messerschmidt, C. and Obermayer, B. and Klinghammer, K. and Ochsenreither, S. and Treue, D. and Stenzinger, A. and Glimm, H. and Fröhling, S. and Kindler, T. and Brandts, C.H. and Schulze-Osthoff, K. and Weichert, W. and Tinhofer, I. and Klauschen, F. and Keilholz, U. and Beule, D. and Rieke, D.T.
bioRxiv
: 586396.
28 March 2019
Circuit-specific dendritic development in the piriform cortex.
Moreno-Velasquez, L. and Kaehne, M. and Lo, H. and Lenzi, S. and Breustedt, J. and Schmitz, D. and Rüdiger, S. and Johenning, F.W.
bioRxiv
: 868075.
8 December 2019
A quantitative modular modeling approach reveals the consequences of different A20 feedback implementations for the NF-κB signaling dynamics.
Mothes, J. and Ipenberg, I. and Arslan, S.Ç. and Benary, U. and Scheidereit, C. and Wolf, J.
bioRxiv
: 582767.
19 March 2019
The conserved histone chaperone LIN-53 links lifespan and healthspan regulation in C. elegans.
Müthel, S. and Uyar, B. and He, M. and Krause, A. and Vitrinel, B. and Bulut, S. and Vasiljevic, D. and Akalin, A. and Kempa, S. and Tursun, B.
bioRxiv
: 539015.
2 February 2019
Polymer-like model to study the dynamics of dynamin filaments on deformable membrane tubes.
Noel, J.K. and Noé, F. and Daumke, O. and Mikhailov, A.S.
bioRxiv
: 686873.
28 June 2019
SCelVis: Powerful explorative single cell data analysis on the desktop and in the cloud.
Obermayer, B. and Holtgrewe, M. and Nieminen, M. and Messerschmidt, C. and Beule, D.
bioRxiv
: 713008.
24 July 2019
Chloroplast cold-resistance is mediated by the acidic domain of the RNA binding protein CP31A.
Okuzaki, A. and Lehniger, M.K. and Muino, J.M. and Lenzen, B. and Rühe, Thilo and Leister, D. and Ohler, U. and Schmitz-Linneweber, C.
bioRxiv
: 832337.
5 December 2019
Low-density granulocytes are a novel immunopathological feature in both multiple sclerosis and neuromyelitis optica spectrum disorder.
Ostendorf, L. and Mothes, R. and van Koppen, S. and Lindquist, R.L. and Bellmann-Strobl, J. and Asseyer, S. and Ruprecht, K. and Alexander, T. and Niesner, R.A. and Hauser, A.E. and Paul, F. and Radbruch, H.
bioRxiv 10
: 668160.
12 June 2019
LiP-Quant, an automated chemoproteomic approach to identify drug targets in complex proteomes.
Piazza, I. and Beaton, N. and Bruderer, R. and Knobloch, T. and Barbisan, C. and Siepe, I. and Rinner, O. and de Souza, N. and Picotti, P. and Reiter, L.
bioRxiv
: 860072.
1 December 2019
A fully phased accurate assembly of an individual human genome.
Porubsky, D. and Ebert, P. and Audano, P.A. and Vollger, M.R. and Harvey, W.T. and Munson, K.M. and Sorensen, M. and Sulovari, A. and Haukness, M. and Ghareghani, M. and Lansdorp, P.M. and Paten, B. and Devine, S.E. and Sanders, A.D. and Lee, C. and Chaisson, M.J.P. and Korbel, J.O. and Eichler, E.E. and Marschall, T.
bioRxiv
: 855049.
26 November 2019
Functional annotation of human long non-coding RNAs via molecular phenotyping.
Ramilowski, J. and Yip, C.W. and Agrawal, S. and Chang, J.C. and Ciani, Y. and Kulakovskiy, I.V. and Mendez, M. and Ooi, J.L.C. and Ouyang, J.F. and Parkinson, N. and Petri, A. and Roos, L. and Severin, J. and Yasuzawa, K. and Abugessaisa, I. and Akalin, A. and Antonov, I. and Arner, E. and Bonetti, A. and Bono, H. and Borsari, B. and Brombacher, F. and Cannistraci, C.V. and Cameron, C.J.F. and Cardenas, R. and Cardon, M. and Chang, H. and Dostie, J. and Ducoli, L. and Favorov, A. and Fort, A. and Garrido, D. and Gil, N. and Gimenez, J. and Guler, R. and Handoko, L. and Harshbarger, J. and Hasegawa, A. and Hasegawa, Y. and Hashimoto, K. and Hayatsu, N. and Heutink, P. and Hirose, T. and Imada, E.L. and Itoh, M. and Kaczkowski, B. and Kanhere, A. and Kawabata, E. and Kawaji, H. and Kawashima, T. and Kelly, T. and Kojima, M. and Kondo, N. and Koseki, H. and Kouno, T. and Kratz, A. and Kurowska-Stolarska, M. and Kwon, A.T.J. and Leek, J. and Lennartsson, A. and Lizio, M. and Lopez, F. and Luginbühl, J. and Maeda, S. and Makeev, V. and Marchionni, L. and Medvedeva, Y.A. and Minoda, A. and Müller, F. and Aguirre, M.M. and Murata, M. and Nishiyori, H. and Nitta, K. and Noguchi, S. and Noro, Y. and Nurtdinov, R. and Okazaki, Y. and Orlando, V. and Paquette, D. and Parr, C. and Rackham, O.J.L. and Rizzu, P. and Sanchez, D.F. and Sandelin, A. and Sanjana, P. and Semple, C.A.M. and Sharma, H. and Shibayama, Y. and Sivaraman, D. and Suzuki, T. and Szumowski, S. and Tagami, M. and Taylor, M.S. and Terao, C. and Thodberg, M. and Thongjuea, S. and Tripathi, V. and Ulitsky, I. and Verardo, R. and Vorontsov, I. and Yamamoto, C. and Young, R.S. and Baillie, J.K. and Forrest, A.R.R. and Guigó, R. and Hoffman, M.M. and Hon, C.C. and Kasukawa, T. and Kauppinen, S. and Kere, J. and Lenhard, B. and Schneider, C. and Suzuki, H. and Yagi, K. and de Hoon, M. and Shin, J.W. and Carninci, P.
bioRxiv
: 700864.
18 July 2019
Single cell tri-channel-processing reveals structural variation landscapes and complex rearrangement processes.
Sanders, A.D. and Meiers, S. and Ghareghani, M. and Porubsky, D. and Jeong, H. and van Vliet, M.A.C.C. and Rausch, T. and Richter-Pechańska, P. and Kunz, J.B. and Jenni, S. and Raeder, B. and Kinanen, V. and Zimmermann, J. and Benes, V. and Schrappe, M. and Mardin, B.R. and Kulozik, A. and Bornhauser, B. and Bourquin, J.P. and Marschall, T. and Korbel, J.O.
bioRxiv
: 849604.
21 November 2019
The transcriptome dynamics of single cells during the cell cycle.
Schwabe, D. and Formichetti, S. and Junker, J.P. and Falcke, M. and Rajewsky, N.
bioRxiv
: 2019.12.23.887570.
26 December 2019
Disease overarching mechanisms that explain and predict outcome of patients with high cardiovascular risk: rationale and design of the Berlin Long-term Observation of vascular events (BeLOVE) study.
Siegerink, B. and Weber, J. and Ahmadi, M. and Eckardt, K.U. and Edelmann, F. and Endres, M. and Gerhardt, H. and Haubold, K. and Hübner, N. and Landmesser, U. and Leistner, D. and Mai, K. and Müller, D.N. and Pieske, B. and Rauch, G. and Schmidt, S. and Schmidt-Ott, K. and Schulz-Menger, J. and Spranger, J. and Pischon, T.
medRxiv
: 19001024.
15 July 2019
Partner-independent fusion gene detection by multiplexed CRISPR/Cas9 enrichment and long-read Nanopore sequencing.
Stangl, C. and de Blank, S. and Renkens, I. and Verbeek, T. and Valle-Inclan, J.E. and Chamorro González, R. and Henssen, A.G. and van Roosmalen, M.J. and Stam, R.W. and Voest, E.E. and Kloosterman, W.P. and van Haaften, G. and Monroe, G.
bioRxiv
: 807545.
22 October 2019
Predicting cellular position in the Drosophila embryo from single-cell Transcriptomics data.
Tanevski, J. and Nguyen, T. and Truong, B. and Karaiskos, N. and Ahsen, M.E. and Zhang, X. and Shu, C. and Xu, K. and Liang, X. and Hu, Y. and Pham, H.V.V. and Xiaomei, L. and Le, T.D. and Tarca, A.L. and Bhatti, G. and Romero, R. and Karathanasis, N. and Loher, P. and Chen, Y. and Ouyang, Z. and Mao, D. and Zhang, Y. and Zand, M. and Ruan, J. and Hafemeister, C. and Qiu, P. and Tran, D. and Nguyen, T. and Gabor, A. and Yu, T. and Glaab, E. and Krause, R. and Banda, P. and Stolovitzky, G. and Rajewsky, N. and Saez-Rodriguez, J. and Meyer, P.
bioRxiv
: 796029.
10 October 2019
UbiFast, a rapid and deep-scale ubiquitylation profiling approach for biology and translational research.
Udeshi, N.D. and Mani, D.C. and Satpathy, S. and Fereshetian, S. and Gasser, J.A. and Svinkina, T. and Ebert, B.L. and Mertins, P. and Carr, S.A.
bioRxiv
: 785378.
27 September 2019
Identification of TMEM206 proteins as pore of ASOR acid-sensitive chloride channels.
Ullrich, F. and Blin, S. and Lazarow, K. and Daubitz, T. and von Kries, J.P. and Jentsch, T.J.
bioRxiv
: 667600.
11 June 2019
Chromatin-sensitive cryptic promoters encode alternative protein isoforms in yeast.
Wei, W. and Hennig, B.P. and Wang, J. and Zhang, Y. and Piazza, I. and Sanchez, Y.P. and Chabbert, C.D. and Adjalley, S.H. and Steinmetz, L.M. and Pelechano, V.
bioRxiv
: 403543.
12 August 2019
Splicing factor Rbm10 facilitates heterochromatin assembly in fission yeast.
Weigt, M. and Gao, Q. and Ban, H. and He, H. and Mastrobuoni, G. and Kempa, S. and Chen, W. and Li, F.
bioRxiv
: 518936.
11 January 2019
Integrative functional genomics decodes herpes simplex virus 1.
Whisnant, A.W. and Jürges, C.S. and Hennig, T. and Wyler, E. and Prusty, B. and Rutkowski, A.J. and L’hernault, A. and Göbel, M. and Döring, K. and Menegatti, J. and Antrobus, R. and Matheson, N.J. and Künzig, F.W.H. and Mastrobuoni, G. and Bielow, C. and Kempa, S. and Chunguang, L. and Dandekar, T. and Zimmer, R. and Landthaler, M. and Grässer, F. and Lehner, P.J. and Friedel, C.C. and Erhard, F. and Dölken, L.
bioRxiv
: 603654.
9 April 2019
Single-cell RNA-sequencing of Herpes simplex virus 1-infected cells identifies NRF2 activation as an antiviral program.
Wyler, E. and Franke, V. and Menegatti, J. and Kocks, C. and Boltengagen, A. and Praktiknjo, S. and Walch-Rückheim, B. and Rajewsky, N. and Grässer, F. and Akalin, A. and Landthaler, M.
bioRxiv
: 566992.
4 March 2019
Endothelial PKA targets ATG16L1 to regulate angiogenesis by limiting autophagy.
Zhao, X. and Nedvetsky, P. and Vion, A.C. and Popp, O. and Zühlke, K. and Dittmar, G. and Klussmann, E. and Gerhardt, H.
bioRxiv
: 573683.
12 March 2019
This list was generated on Thu Apr 25 02:14:15 2024 CEST.
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