A
Impaired human hematopoiesis due to a cryptic intronic splicing mutation.
Abdulhay, N.J., Fiorini, C., Verboon, J.M., Ludwig, L.S., Ulirsch, J.C., Zieger, B., Lareau, C.A., Mi, X., Roy, A., Obeng, E.A., Erlacher, M., Gupta, N., Gabriel, S.B., Ebert, B.L., Niemeyer, C.M., Khoriaty, R.N., Ancliff, P., Gazda, H.T., Wlodarski, M.W. and Sankaran, V.G.
Journal of Experimental Medicine 216
(5): 1050-1060.
6 May 2019
Critical role for piccolo in synaptic vesicle retrieval.
Ackermann, F., Schink, K.O., Bruns, C., Izsvák, Z., Hamra, F.K., Rosenmund, C. and Garner, C.C.
eLife 8
: e46629.
10 May 2019
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.
Ackermann, T., Hartleben, G., Müller, C., Mastrobuoni, G., Groth, M., Sterken, B.A., Zaini, M.A., Youssef, S.A., Zuidhof, H.R., Krauss, S.R., Kortman, G., de Haan, G., de Bruin, A., Wang, Z.Q., Platzer, M., Kempa, S. and Calkhoven, C.F.
Communications Biology 2
: 208.
14 June 2019
Development of robust 17(R),18(S)-epoxyeicosatetraenoic acid (17,18-EEQ) analogues as potential clinical antiarrhythmic agents.
Adebesin, A.M., Wesser, T., Vijaykumar, J., Konkel, A., Paudyal, M., Lossie, J., Zhu, C., Westphal, C., Puli, N., Fischer, R., Schunck, W.H. and Falck, J.
Journal of Medicinal Chemistry 62
(22): 10124-10143.
27 November 2019
A novel non-invasive method to detect RELM beta transcript in gut barrier related changes during a gastrointestinal nematode infection.
Ahmed, N., Heitlinger, E., Affinass, N., Kühl, A.A., Xenophontos, N., Jarquin, V.H., Jost, J., Steinfelder, S. and Hartmann, S.
Frontiers in Immunology 10
: 445.
March 2019
Lifestyle interventions in Muslim patients with metabolic syndrome: a feasibility study.
Aktas, M.F., Mähler, A., Hamm, M., Perger, G., Simon, F., Westenhöfer, J., Luft, F.C. and Boschmann, M.
European Journal of Clinical Nutrition 73
(5): 805-808.
May 2019
RIKADA study reveals risk factors in pediatric primary cardiomyopathy.
Al-Wakeel-Marquard, N., Degener, F., Herbst, C., Kühnisch, J., Dartsch, J., Schmitt, B., Kuehne, T., Messroghli, D., Berger, F. and Klaassen, S.
Journal of the American Heart Association 8
(15): e012531.
6 August 2019
Pressurized intraperitoneal aerosol chemotherapy and its effect on gastric-cancer-derived peritoneal metastases: an overview.
Alberto, M., Brandl, A., Garg, P.K., Gül-Klein, S., Dahlmann, M., Stein, U. and Rau, B.
Clinical and Experimental Metastasis 36
(1): 1-14.
February 2019
Quantification and characterization of radical production in human, animal and 3D skin models during sun irradiation measured by EPR spectroscopy.
Albrecht, S., Elpelt, A., Kasim, C., Reble, C., Mundhenk, L., Pischon, H., Hedtrich, S., Witzel, C., Lademann, J., Zastrow, L., Beckers, I. and Meinke, M.C.
Free Radical Biology and Medicine 131
: 299-308.
1 February 2019
Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids.
Alcala, N., Leblay, N., Gabriel, A.A.G., Mangiante, L., Hervas, D., Giffon, T., Sertier, A.S., Ferrari, A., Derks, J., Ghantous, A., Delhomme, T.M., Chabrier, A., Cuenin, C., Abedi-Ardekani, B., Boland, A., Olaso, R., Meyer, V., Altmuller, J., Le Calvez-Kelm, F., Durand, G., Voegele, C., Boyault, S., Moonen, L., Lemaitre, N., Lorimier, P., Toffart, A.C., Soltermann, A., Clement, J.H., Saenger, J., Field, J.K., Brevet, M., Blanc-Fournier, C., Galateau-Salle, F., Le Stang, N., Russell, P.A., Wright, G., Sozzi, G., Pastorino, U., Lacomme, S., Vignaud, J.M., Hofman, V., Hofman, P., Brustugun, O.T., Lund-Iversen, M., Thomas de Montpreville, V., Muscarella, L.A., Graziano, P., Popper, H., Stojsic, J., Deleuze, J.F., Herceg, Z., Viari, A., Nuernberg, P., Pelosi, G., Dingemans, A.M.C., Milione, M., Roz, L., Brcic, L., Volante, M., Papotti, M.G., Caux, C., Sandoval, J., Hernandez-Vargas, H., Brambilla, E., Speel, E.J.M., Girard, N., Lantuejoul, S., McKay, J.D., Foll, M. and Fernandez-Cuesta, L.
Nature Communications 10
(1): 3407.
20 August 2019
Fatty acid-binding protein 4 and risk of type 2 diabetes, myocardial infarction and stroke: a prospective cohort study.
Aleksandrova, K., Drogan, D., Weikert, C., Schulze, M.B., Fritsche, A., Boeing, H. and Pischon, T.
Journal of Clinical Endocrinology and Metabolism 104
(12): 5991-6002.
December 2019
Biological determinants of physical activity across the life course: a "Determinants of Diet and Physical Activity" (DEDIPAC) umbrella systematic literature review.
Aleksovska, K., Puggina, A., Giraldi, L., Buck, C., Burns, C., Cardon, G., Carlin, A., Chantal, S., Ciarapica, D., Colotto, M., Condello, G., Coppinger, T., Cortis, C., D'Haese, S., De Craemer, M., Di Blasio, A., Hansen, S., Iacoviello, L., Issartel, J., Izzicupo, P., Jaeschke, L., Kanning, M., Kennedy, A., Ling, F., Luzak, A., Napolitano, G., Nazare, J.A., Perchoux, C., Pischon, T., Polito, A., Sannella, A., Schulz, H., Sohun, R., Steinbrecher, A., Schlicht, W., Ricciardi, W., MacDonncha, C., Capranica, L. and Boccia, S.
Sports Medicine - Open 5
(1): 2.
8 January 2019
ACE2 in brain physiology and pathophysiology: evidence from transgenic animal models.
Alenina, N. and Bader, M.
Neurochemical Research 44
(6): 1323-1329.
June 2019
Genetic models.
Alenina, N. and Bader, M.
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Angiotensin-(1-7) : a comprehensive review.
Springer, Cham, 35-51.
ISBN 978-3-030-22695-4
2019
Polycystin-1 assembles with Kv channels to govern cardiomyocyte repolarization and contractility.
Altamirano, F., Schiattarella, G.G., French, K.M., Kim, S.Y., Engelberger, F., Kyrychenko, S., Villalobos, E., Tong, D., Schneider, J.W., Ramirez-Sarmiento, C.A., Lavandero, S., Gillette, T.G. and Hill, J.A.
Circulation 140
(11): 921-936.
10 September 2019
Assessment of bones deficient in fibrillin-1 microfibrils reveals pronounced sex differences.
Altinbas, L., Bormann, N., Lehmann, D., Jeuthe, S., Wulsten, D., Kornak, U., Robinson, P.N., Wildemann, B. and Kararigas, G.
International Journal of Molecular Sciences 20
(23): 6059.
1 December 2019
StaBle angina: peRceptIon of neeDs, quality of life and manaGemEnt of patients (BRIDGE study) - a multinational European physician survey.
Ambrosio, G., Collins, P., Dechend, R., Lopez-Sendon, J., Manolis, A.J. and Camm, A.J.
Angiology 70
(5): 397-406.
1 May 2019
CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing.
Andersch, L., Radke, J., Klaus, A., Schwiebert, S., Winkler, A., Schumann, E., Grunewald, L., Zirngibl, F., Flemmig, C., Jensen, M.C., Rossig, C., Joussen, A., Henssen, A., Eggert, A., Schulte, J.H. and Künkele, A.
BMC Cancer 19
(1): 895.
9 September 2019
Endothelial metabolism - more complex (III) than previously thought.
Andrade, J. and Potente, M.
Nature Metabolism 1
(1): 14-15.
January 2019
Analysis of NTRK expression in gastric and esophageal adenocarcinoma (AGE) with pan-TRK immunohistochemistry.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Horst, D., Rau, B., Stein, U. and Treese, C.
Pathology Research and Practice 215
(11): 152662.
November 2019
Regulation of influenza a virus mRNA splicing by CLK1.
Artarini, A., Meyer, M., Shin, Y.J., Huber, K., Hilz, N., Bracher, F., Eros, D., Orfi, L., Keri, G., Goedert, S., Neuenschwander, M., von Kries, J., Domovich-Eisenberg, Y., Dekel, N., Szabadkai, I., Lebendiker, M., Horváth, Z., Danieli, T., Livnah, O., Moncorgé, O., Frise, R., Barclay, W., Meyer, T.F. and Karlas, A.
Antiviral Research 168
: 187-196.
August 2019
Saffron: The golden spice with therapeutic properties on digestive diseases.
Ashktorab, H., Soleimani, A., Singh, G., Amr, A., Tabtabaei, S., Latella, G., Stein, U., Akhondzadeh, S., Solanki, N., Gondré-Lewis, M.C., Habtezion, A. and Brim, H.
Nutrients 11
(5): 943.
26 April 2019
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Vision and vision-related measures in progressive multiple sclerosis.
Backner, Y., Petrou, P., Glick-Shames, H., Raz, N., Zimmermann, H., Jost, R., Scheel, M., Paul, F., Karussis, D. and Levin, N.
Frontiers in Neurology 10
: 455.
May 2019
Serotonylation: serotonin signaling and epigenetics.
Bader, M.
Frontiers in Molecular Neuroscience 12
: 288.
21 November 2019
hnRNP-K targets open chromatin in mouse embryonic stem cells in concert with multiple regulators.
Bakhmet, E.I., Nazarov, I.B., Gazizova, A.R., Vorobyeva, N.E., Kuzmin, A.A., Gordeev, M.N., Sinenko, S.A., Aksenov, N. D., Artamonova, T.O., Khodorkovskii, M.A., Alenina, N., Onichtchouk, D., Wu, G., Schöler, H.R. and Tomilin, A.N.
Stem Cells 37
(8): 1018-1029.
August 2019
Retinal inner nuclear layer volume reflects inflammatory disease activity in multiple sclerosis; a longitudinal OCT study.
Balk, L.J., Coric, D., Knier, B., Zimmermann, H.G., Behbehani, R., Alroughani, R., Martinez-Lapiscina, E.H., Brandt, A.U., Sánchez-Dalmau, B., Vidal-Jordana, A., Albrecht, P., Koska, V., Havla, J., Pisa, M., Nolan, R.C., Leocani, L., Paul, F., Aktas, O., Montalban, X., Balcer, L.J., Villoslada, P., Outteryck, O., Korn, T. and Petzold, A.
Multiple Sclerosis Journal Experimental Translational and Clinical 5
(3): 2055217319871582.
1 July 2019
Small molecules for modulating the localisation of the water channel aquaporin-2-disease relevance and perspectives for targeting local cAMP signalling.
Baltzer, S. and Klussmann, E.
Naunyn-Schmiedeberg's Archives of Pharmacology 392
(9): 1049-1064.
September 2019
Common mode of remodeling AAA ATPases p97/CDC48 by their disassembling cofactors ASPL/PUX1.
Banchenko, S., Arumughan, A., Petrović, S., Schwefel, D., Wanker, E.E., Roske, Y. and Heinemann, U.
Structure 27
(12): 1830-1841.
3 December 2019
Linoleic acid metabolite DiHOME decreases post-ischemic cardiac recovery in murine hearts.
Bannehr, M., Löhr, L., Gelep, J., Haverkamp, W., Schunck, W.H., Gollasch, M. and Wutzler, A.
Cardiovascular Toxicology 19
(4): 365-371.
August 2019
In contrast to Western diet, a plant-based, high-fat, low-sugar diet does not exacerbate retinal endothelial injury in streptozotocin-induced diabetes.
Barakat, A., Nakao, S., Zandi, S., Sun, D., Schmidt-Ullrich, R., Hayes, K.C. and Hafezi-Moghadam, A.
FASEB Journal 33
(9): 10327-10338.
September 2019
Short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H., Balogh, A., Yakoub, M., Homann, S., Markó, L., Höges, S., Tsvetkov, D., Krannich, A., Wundersitz, S., Avery, E.G., Haase, N., Kräker, K., Hering, L., Maase, M., Kusche-Vihrog, K., Grandoch, M., Fielitz, J., Kempa, S., Gollasch, M., Zhumadilov, Z., Kozhakhmetov, S., Kushugulova, A., Eckardt, K.U., Dechend, R., Rump, L.C., Forslund, S.K., Müller, D.N., Stegbauer, J. and Wilck, N.
Circulation 139
(11): 1407-1421.
12 March 2019
Precarious symbiosis between host and microbiome in cardiovascular health.
Bartolomaeus, H., Markó, L., Wilck, N., Luft, F.C., Forslund, S.K. and Muller, D.N.
Hypertension 73
(5): 926-935.
May 2019
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.
Basheer, F., Giotopoulos, G., Meduri, E., Yun, H., Mazan, M., Sasca, D., Gallipoli, P., Marando, L., Gozdecka, M., Asby, R., Sheppard, O., Dudek, M., Bullinger, L., Döhner, H., Dillon, R., Freeman, S., Ottmann, O., Burnett, A., Russell, N., Papaemmanuil, E., Hills, R., Campbell, P., Vassiliou, G.S.. and Huntly, B.J.P.
Journal of Experimental Medicine 216
(4): 966-981.
1 April 2019
All-in-one confocal and widefield fluorescence microscope to investigate membrane receptor dynamics.
Bathe-Peters, M., Gmach, P., Annibale, P. and Lohse, M.J.
In: Imaging and Applied Optics Congress 2019 (COSI, IS, MATH, pcAOP), 24-27 Jun 2019, Munich, Germany.
2019
Gain-of-function mutations in KCNN3 encoding the small-conductance Ca(2+)-activated K(+) channel SK3 cause Zimmermann-Laband syndrome.
Bauer, C.K., Schneeberger, P.E., Kortüm, F., Altmüller, J., Santos-Simarro, F., Baker, L., Keller-Ramey, J., White, S.M., Campeau, P.M., Gripp, K.W. and Kutsche, K.
American Journal of Human Genetics 104
(6): 1139-1157.
6 June 2019
Analysis of correlation-based biomolecular networks from different omics data by fitting stochastic block models.
Baum, K., Rajapakse, J.C. and Azuaje, F.
F1000Research 8
: 465.
27 August 2019
Of gene expression and cell division time: a mathematical framework for advanced differential gene expression and data analysis.
Baum, K., Schuchhardt, J., Wolf, J. and Busse, D.
Cell Systems 9
(6): 569-579.
18 December 2019
Association between physical activity and risk of hepatobiliary cancers: a multinational cohort study.
Baumeister, S.E., Schlesinger, S., Aleksandrova, K., Jochem, C., Jenab, M., Gunter, M.J., Overvad, K., Tjønneland, A., Boutron-Ruault, M.C., Carbonnel, F., Fournier, A., Kühn, T., Kaaks, R., Pischon, T., Boeing, H., Trichopoulou, A., Bamia, C., La Vecchia, C., Masala, G., Panico, S., Fasanelli, F., Tumino, R., Grioni, S., de Mesquita, B.B., Vermeulen, R., May, A.M., Borch, K.B., Oyeyemi, S.O., Ardanaz, E., Rodríguez-Barranco, M., López, M.D.C., Felez-Nobrega, M., Sonestedt, E., Ohlsson, B., Hemmingsson, O., Werner, M., Perez-Cornago, A., Ferrari, P., Stepien, M., Freisling, H., Tsilidis, K.K., Ward, H., Riboli, E., Weiderpass, E. and Leitzmann, M.F.
Journal of Hepatology 70
(5): 885-892.
May 2019
Simultaneous high-resolution cardiac T(1) mapping and cine imaging using model-based iterative image reconstruction.
Becker, K.M., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C.
Magnetic Resonance in Medicine 81
(2): 1080-1091.
February 2019
Controlling nuclear NF-κB dynamics by β-TrCP-insights from a computational model.
Benary, U. and Wolf, J.
Biomedicines 7
(2): 40.
27 May 2019
Modelling the DNA topology: the effect of the loop bending on G-quadruplex stability.
Bergues-Pupo, A.E., Falo, F. and Fiasconaro, A.
Journal of Statistical Mechanics: Theory and Experiment 2019
(9): 094004.
2 September 2019
Does divergent binding pocket closure drive ligand bias for class A GPCRs?
Bermudez, M. and Bock, A.
Trends in Pharmacological Sciences 40
(4): 236-239.
April 2019
Tight junction proteins at the blood-brain barrier: far more than claudin-5.
Berndt, P., Winkler, L., Cording, J., Breitkreuz-Korff, O., Rex, A., Dithmer, S., Rausch, V., Blasig, R., Richter, M., Sporbert, A., Wolburg, H., Blasig, I.E. and Haseloff, R.F.
Cellular and Molecular Life Sciences 76
(10): 1987-2002.
May 2019
Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy.
Bhaskara, R.M., Grumati, P., Garcia-Pardo, J., Kalayil, S., Covarrubias-Pinto, A., Chen, W., Kudryashev, M., Dikic, I. and Hummer, G.
Nature Communications 10
(1): 2370.
30 May 2019
Modeling single-molecule conformations of the HoxD region in mouse embryonic stem and cortical neuronal cells.
Bianco, S., Annunziatella, C., Andrey, G., Chiariello, A.M., Esposito, A., Fiorillo, L., Prisco, A., Conte, M., Campanile, R. and Nicodemi, M.
Cell Reports 28
(6): 1574-1583.
6 August 2019
Editorial overview: Genome architecture and expression.
Bickmore, W. and Pombo, A.
Current Opinion in Genetics & Development 55
: iii-iv.
April 2019
Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger, K.J., Neukam, M., Tattikota, S.G., Qadri, F., Puchkov, D., Willmes, D.M., Wurmsee, S., Geisberger, S., Dechend, R., Raile, K., Kurth, T., Nguyen, G., Poy, M.N., Solimena, M., Muller, D.N. and Birkenfeld, A.L.
Proceedings of the National Academy of Sciences of the United States of America 116
(40): 19983-19988.
1 October 2019
Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein.
Birol, M., Wojcik, S.P., Miranker, A.D. and Rhoades, E.
PLoS Biology 17
(6): e3000318.
18 June 2019
Aldosterone, salt, and potassium intakes as predictors of pregnancy outcome, including preeclampsia.
Birukov, A., Andersen, L.B., Herse, F., Rakova, N., Kitlen, G., Kyhl, H.B., Golic, M., Haase, N., Kräker, K., Müller, D.N., Jørgensen, J.S., Andersen, M.S., Dechend, R. and Jensen, B.L.
Hypertension 74
(2): 391-398.
August 2019
Regulatory antibodies against GPCR in women ten years after early-onset preeclampsia.
Birukov, A., Muijsers, H.E.C., Heidecke, H., Drost, J.T., Cunnigham, M.W., Kraker, K., Haase, N., Frolova, A., Müller, D.N., Herse, F., Maas, A.H.E.M. and Dechend, R.
Frontiers in Bioscience 24
: 1462-1476.
1 June 2019
A clonal expression biomarker associates with lung cancer mortality.
Biswas, D., Birkbak, N.J., Rosenthal, R., Hiley, C.T., Lim, E.L., Papp, K., Boeing, S., Krzystanek, M., Djureinovic, D., La Fleur, L., Greco, M., Döme, B., Fillinger, J., Brunnström, H., Wu, Y., Moore, D.A., Skrzypski, M., Abbosh, C., Litchfield, K., Al Bakir, M., Watkins, T.B.K., Veeriah, S., Wilson, G.A., Jamal-Hanjani, M., Moldvay, J., Botling, J., Chinnaiyan, A.M., Micke, P., Hackshaw, A., Bartek, J., Csabai, I., Szallasi, Z., Herrero, J., McGranahan, N. and Swanton, C.
Nature Medicine 25
(10): 1540-1548.
October 2019
Diagnostik und Therapie von Tuberkulose unter Immuntherapien für Multiple Sklerose : aktueller Stand und Empfehlungen in Deutschland [Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : current status and recommendations in Germany].
Bittner, S., Engel, S., Lange, C., Weber, M.S., Haghikia, A., Luessi, F., Korn, T., Klotz, L., Bayas, A., Paul, F., Heesen, C., Stangel, M., Wildemann, B., Bergh, F.T., Tackenberg, B., Trebst, C., Warnke, C., Linker, R., Kerschensteiner, M., Zettl, U., Tumani, H., Brück, W., Meuth, S.G., Kümpfel, T., Hemmer, B., Wiendl, H., Gold, R. and Zipp, F.
Nervenarzt 90
(12): 1245-1253.
December 2019
Identification and ranking of recurrent neo-epitopes in cancer.
Blanc, E., Holtgrewe, M., Dhamodaran, A., Messerschmidt, C., Willimsky, G., Blankenstein, T. and Beule, D.
BMC Medical Genomics 12
: 171.
27 November 2019
Subclinical myocardial injury in patients with Facioscapulohumeral muscular dystrophy 1 and preserved ejection fraction - assessment by cardiovascular magnetic resonance.
Blaszczyk, E., Grieben, U., von Knobelsdorff-Brenkenhoff, F., Kellman, P., Schmacht, L., Funk, S., Spuler, S. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 21
(1): 25.
29 April 2019
Pregnancy galectinology: insights into a complex network of glycan binding proteins.
Blois, S.M., Dveksler, G., Vasta, G.R., Freitag, N., Blanchard, V. and Barrientos, G.
Frontiers in Immunology 10
: 1166.
May 2019
Chiral lipidomics of monoepoxy and monohydroxy metabolites derived from long-chain polyunsaturated fatty acids.
Blum, M., Dogan, I., Karber, M., Rothe, M. and Schunck, W.H.
Journal of Lipid Research 60
(1): 135-148.
January 2019
getITD for FLT3-ITD-based MRD monitoring in AML.
Blätte, T.J., Schmalbrock, L.K., Skambraks, S., Lux, S., Cocciardi, S., Dolnik, A., Döhner, H., Döhner, K. and Bullinger, L.
Leukemia 33
(10): 2535-2539.
October 2019
Identification and regulation of the long non-coding RNA Heat2 in heart failure.
Boeckel, J.N., Perret, M.F., Glaser, S.F., Seeger, T., Heumüller, A.W., Chen, W., John, D., Kokot, K.E., Katus, H.A., Haas, J., Lackner, M.K., Kayvanpour, E., Grabe, N., Dieterich, C., von Haehling, S., Ebner, N., Hünecke, S., Leuschner, F., Fichtlscherer, S., Meder, B., Zeiher, A.M., Dimmeler, S. and Keller, T.
Journal of Molecular and Cellular Cardiology 126
: 13-22.
January 2019
The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A., Babila, J.T., Wiglenda, T., Diez, L., Jacob, M., Nietfeld, W., Huska, M.R., Haenig, C., Groenke, N., Buntru, A., Blanc, E., Meier, J.C., Vannoni, E., Erck, C., Friedrich, B., Martens, H., Neuendorf, N., Schnoegl, S., Wolfer, D.P., Loos, M., Beule, D., Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 26
(1): 109-120.
17 January 2019
Cardiorenal sodium MRI at 7.0 Tesla using a 4/4 channel (1)H/(23)Na radiofrequency antenna array.
Boehmert, L., Kuehne, A., Waiczies, H., Wenz, D., Eigentler, T.W., Funk, S., von Knobelsdorff-Brenkenhoff, F., Schulz-Menger, J., Nagel, A.M., Seeliger, E. and Niendorf, T.
Magnetic Resonance in Medicine 82
(6): 2343-2356.
December 2019
The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B., Wang, X., Eichelbaum, K., Sadewasser, A., Husic, I., Paki, K., Budt, M., Hergeselle, M., Vetter, B., Hou, J., Chen, W., Wiebusch, L., Meyer, I.M., Wolff, T. and Selbach, M.
Nature Communications 10
(1): 5518.
4 December 2019
New targeted agents in acute myeloid leukemia: new hope on the rise.
Bohl, S.R., Bullinger, L. and Rücker, F.G.
International Journal of Molecular Sciences 20
(8)
23 April 2019
Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage.
Boltze, J., Ferrara, F., Hainsworth, A.H., Bridges, L.R., Zille, M., Lobsien, D., Barthel, H., McLeod, D.D., Gräßer, F., Pietsch, S., Schatzl, A.K., Dreyer, A.Y. and Nitzsche, B.
Journal of Cerebral Blood Flow and Metabolism 39
(12): 2521-2535.
1 December 2019
WiPP: workflow for improved peak picking for gas chromatography-mass spectrometry (GC-MS) data.
Borgsmüller, N., Gloaguen, Y., Opialla, T., Blanc, E., Sicard, E., Royer, A.L., Le Bizec, B., Durand, S., Migné, C., Pétéra, M., Pujos-Guillot, E., Giacomoni, F., Guitton, Y., Beule, D. and Kirwan, J.
Metabolites 9
(9): 171.
21 August 2019
Somatostatin 2 receptors in the spinal cord tonically restrain thermogenic, cardiac and other sympathetic outflows.
Bowman, B.R., Bokiniec, P., McMullan, S., Goodchild, A.K. and Burke, P.G.R.
Frontiers in Neuroscience 13
: 121.
February 2019
Light-microscopy methods in C. elegans research.
Breimann, L., Preusser, F. and Preibisch, S.
Current Opinion in Systems Biology 13
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1 March 2019
Microbiome determinants and physiological effects of the benzoate-hippurate microbial-host co-metabolic pathway.
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16 December 2019
Crowdfunded whole-genome sequencing of the celebrity cat Lil BUB identifies causal mutations for her osteopetrosis and polydactyly.
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RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses.
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2 August 2019
IDH2 inhibition: another piece to the puzzle.
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14 February 2019
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10 December 2019
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Analysis of the CDK4/6 cell cycle pathway in leiomyosarcomas as a potential target for inhibition by palbociclib.
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Multi-parameter immune profiling of peripheral blood mononuclear cells by multiplexed single-cell mass cytometry in patients with early multiple sclerosis.
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Mesothelial-mesenchymal transitions in embryogenesis.
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Nephropathy in hypertensive animals is linked to M2 macrophages and increased expression of the YM1/Chi3l3 protein.
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Integrative approaches in structural biology: a more complete picture from the combination of individual techniques.
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Postnatal Tshz3 deletion drives altered corticostriatal function and autism spectrum disorder-like behavior.
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15 August 2019
Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.
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Comparing agent‐based delivery of DNA and PNA forced intercalation (FIT) probes for multicolor mRNA imaging.
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A cellular mechanism underlying enhanced capability for complex olfactory discrimination learning.
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Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.
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Current and future treatment strategies for rhabdomyosarcoma.
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A missense mutation in SNRPE linked to non-syndromal microcephaly interferes with U snRNP assembly and pre-mRNA splicing.
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Porphyromonas gingivalis impairs oral epithelial barrier through targeting GRHL2.
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Small and large ribosomal subunit deficiencies lead to distinct gene expression signatures that reflect cellular growth rate.
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Blood pressure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) controversies conference.
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Imaging markers of disability in aquaporin-4 immunoglobulin G seropositive neuromyelitis optica: a graph theory study.
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Brain Communications 1
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16 October 2019
Spinal cord lesions and atrophy in NMOSD with AQP4-IgG and MOG-IgG associated autoimmunity.
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December 2019
Possible digenic disease in a caucasian family with COL4A3 and COL4A5 mutations.
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March 2019
Maximizing binary interactome mapping with a minimal number of assays.
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29 August 2019
deltaTE: detection of translationally regulated genes by integrative analysis of Ribo-seq and RNA-seq data.
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December 2019
Widespread translational control of fibrosis in the human heart by RNA-binding proteins.
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Circulation 140
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10 September 2019
Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients.
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7 March 2019
Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders.
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Lancet Neurology 18
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February 2019
Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
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18 March 2019
Autophagy in the renewal, differentiation and homeostasis of immune cells.
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March 2019
Estrus-cycle regulation of cortical inhibition.
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18 February 2019
Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation.
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NG-meta-profiler: fast processing of metagenomes using NGLess, a domain-specific language.
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3 June 2019
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Standardization of T1w/T2w ratio improves detection of tissue damage in multiple sclerosis.
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Multiscale modeling of dyadic structure-function relation in ventricular cardiac myocytes.
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October 2019
Interleukin-4 supplementation improves the pathophysiology of hypertension in response to placental ischemia in RUPP rats.
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Pancreas organogenesis: the interplay between surrounding microenvironment(s) and epithelium-intrinsic factors.
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Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial.
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Wnt11/Fzd7 signaling compartmentalizes AKAP2/PKA to regulate L-type Ca(2+) channel.
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Novel mutations in KMT2B offer pathophysiological insights into childhood-onset progressive dystonia.
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Untargeted metabolomic analysis and pathway discovery in perinatal asphyxia and hypoxic-ischaemic encephalopathy.
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PRISMA: Protein Interaction Screen on Peptide Matrix reveals interaction footprints and modifications- dependent interactome of intrinsically disordered C/EBPb.
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October 2019
Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma.
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Rapid molecular evolution of pain insensitivity in multiple African rodents.
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31 May 2019
Uncovering convolutional neural network decisions for diagnosing multiple sclerosis on conventional MRI using layer-wise relevance propagation.
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A cellular model of Brugada syndrome with SCN10A variants using human-induced pluripotent stem cell-derived cardiomyocytes.
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Studying Brugada syndrome with an SCN1B variants in human-induced pluripotent stem cell-derived cardiomyocytes.
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1 November 2019
Gadolinium in human brain sections and colocalization with other elements.
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January 2019
Insight into the redox status of inflammatory skin equivalents as determined by EPR spectroscopy.
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Akutes pulmorenales Syndrom auf der Intensivstation: Rationale Diagnostik und Therapie [Acute pulmonary-renal syndrome in the intensive care unit: rational diagnostics and treatment].
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2 October 2019
Role of Zeb2/Sip1 in neuronal development.
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15 February 2019
Models of polymer physics for the architecture of the cell nucleus.
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July 2019
Genotyping of circulating tumor DNA in cholangiocarcinoma reveals diagnostic and prognostic information.
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On the presence and functional significance of sympathetic premotor neurons with collateralized spinal axons in the rat.
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1 July 2019
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.
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Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
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Nature Neuroscience 22
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Associations of the metabolic syndrome and its components with cognitive impairment in older adults.
Feinkohl, I., Janke, J., Hadzidiakos, D., Slooter, A., Winterer, G., Spies, C. and Pischon, T.
BMC Geriatrics 19
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7 March 2019
Blimp1(+) cells generate functional mouse sebaceous gland organoids in vitro.
Feldman, A., Mukha, D., Maor, I.I., Sedov, E., Koren, E., Yosefzon, Y., Shlomi, T. and Fuchs, Y.
Nature Communications 10
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28 May 2019
Autocalibrated multiband CAIPIRINHA with through-time encoding: proof of principle and application to cardiac tissue phase mapping.
Ferrazzi, G., Bassenge, J.P., Wink, C., Ruh, A., Markl, M., Moeller, S., Metzger, G.J., Ittermann, B. and Schmitter, S.
Magnetic Resonance in Medicine 81
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February 2019
Eleven loci with new reproducible genetic associations with allergic disease risk.
Ferreira, M.A., Vonk, J.M., Baurecht, H., Marenholz, I., Tian, C., Hoffman, J.D., Helmer, Q., Tillander, A., Ullemar, V., Lu, Y., Rüschendorf, F., Hinds, D.A., Hübner, N., Weidinger, S., Magnusson, P.K., Jorgenson, E., Lee, Y.A., Boomsma, D.I., Karlsson, R., Almqvist, C., Koppelman, G.H. and Paternoster, L.
Journal of Allergy and Clinical Immunology 143
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February 2019
Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines.
Filippi, M., Preziosa, P., Banwell, B.L., Barkhof, F., Ciccarelli, O., De Stefano, N., Geurts, J.J.G., Paul, F., Reich, D.S., Toosy, A.T., Traboulsee, A., Wattjes, M.P., Yousry, T.A., Gass, A., Lubetzki, C., Weinshenker, B.G. and Rocca, M.A.
Brain 142
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July 2019
The role of Wnt and R-spondin in the stomach during health and disease.
Fischer, A.S. and Sigal, M.
Biomedicines 7
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19 June 2019
Signals trigger state-specific transcriptional programs to support diversity and homeostasis in immune cells.
Fischer, C., Metsger, M., Bauch, S., Vidal, R., Böttcher, M., Grote, P., Kliem, M. and Sauer, S.
Science Signaling 12
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14 May 2019
Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils.
Fischer, J., Walter, C., Tönges, A., Aleth, H., Costa Jordão, M.J., Leddin, M., Gröning, V., Erdmann, T., Lenz, G., Roth, J., Vogl, T., Prinz, M., Dugas, M., Jacobsen, I.D. and Rosenbauer, F.
Nature Immunology 20
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May 2019
Cluster binding studies with two anti-Thomsen-Friedenreich (anti-core-1, CD176, TF) antibodies: evidence for a multiple TF epitope.
Flechner, A., Butschak, G., Löffler, A., Rühmann, J., Nishimura, S.I., Dölling, R., Purfürst, B., Goletz, S., Danielczyk, A. and Karsten, U.
International Immunopharmacology 72
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July 2019
The transcription factor Hey and nuclear lamins specify and maintain cell identity.
Flint Brodsly, N., Bitman-Lotan, E., Boico, O., Shafat, A., Monastirioti, M., Gessler, M., Delidakis, C., Rincon-Arano, H. and Orian, A.
eLife 8
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16 July 2019
Unstable TTTTA/TTTCA expansions in MARCH6 are associated with Familial Adult Myoclonic Epilepsy type 3.
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Nature Communications 10
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29 October 2019
Evolution of protein domain architectures.
Forslund, S.K., Kaduk, M. and Sonnhammer, E.L.L.
Methods in Molecular Biology 1910
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2019
The role of receptor MAS in microglia-driven retinal vascular development.
Foulquier, S., Caolo, V., Swennen, G., Milanova, I., Reinhold, S., Recarti, C., Alenina, N., Bader, M., Steckelings, U M., Vanmierlo, T., Post, M.J., Jones, E.A., van Oostenbrugge, R.J. and Unger, T.
Angiogenesis 22
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November 2019
Circular RNAs in clear cell renal cell carcinoma: their microarray-based identification, analytical validation, and potential use in a clinico-genomic model to improve prognostic accuracy.
Franz, A., Ralla, B., Weickmann, S., Jung, M., Rochow, H., Stephan, C., Erbersdobler, A., Kilic, E., Fendler, A. and Jung, K.
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30 September 2019
Specific chromatin changes mark lateral organ founder cells in the Arabidopsis inflorescence meristem.
Frerichs, A., Engelhorn, J., Altmüller, J., Gutierrez-Marcos, J. and Werr, W.
Journal of Experimental Botany 70
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1 August 2019
Role of donor clonal hematopoiesis in allogeneic hematopoietic stem-cell transplantation.
Frick, M., Chan, W., Arends, C.M., Hablesreiter, R., Halik, A., Heuser, M., Michonneau, D., Blau, O., Hoyer, K., Christen, F., Galan-Sousa, J., Noerenberg, D., Wais, V., Stadler, M., Yoshida, K., Schetelig, J., Schuler, E., Thol, F., Clappier, E., Christopeit, M., Ayuk, F., Bornhäuser, M., Blau, I.W., Ogawa, S., Zemojtel, T., Gerbitz, A., Wagner, E.M., Spriewald, B.M., Schrezenmeier, H., Kuchenbauer, F., Kobbe, G., Wiesneth, M., Koldehoff, M., Socié, G., Kroeger, N., Bullinger, L., Thiede, C. and Damm, F.
Journal of Clinical Oncology 37
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10 February 2019
Protease-activated receptor 2 deficiency mediates cardiac fibrosis and diastolic dysfunction.
Friebel, J., Weithauser, A., Witkowski, M., Rauch, B.H., Savvatis, K., Dörner, A., Tabaraie, T., Kasner, M., Moos, V., Bösel, D., Gotthardt, M., Radke, M.H., Wegner, M., Bobbert, P., Lassner, D., Tschöpe, C., Schutheiss, H.P., Felix, S.B., Landmesser, U. and Rauch, U.
European Heart Journal 40
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21 October 2019
Stochastic transcription in the p53-mediated response to DNA damage is modulated by burst frequency.
Friedrich, D., Friedel, L., Finzel, A., Herrmann, A., Preibisch, S. and Loewer, A.
Molecular Systems Biology 15
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1 December 2019
Modified protocol of harvesting, extraction, and normalization approaches for gas chromatography mass spectrometry-based metabolomics analysis of adherent cells grown under high fetal calf serum conditions.
Fritsche-Guenther, R., Bauer, A., Gloaguen, Y., Lorenz, M. and Kirwan, J.A.
Metabolites 10
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18 December 2019
Editorial: critical issues in lymphoma management.
Fuchs, D. and Schmitt, C.A.
memo: Magazine of European Medical Oncology 12
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March 2019
Metabolic modulation regulates cardiac wall morphogenesis in zebrafish.
Fukuda, R., Aharonov, A., Ong, Y.T., Stone, O.A., El-Brolosy, M., Maischein, H.M., Potente, M., Tzahor, El. and Stainier, D.Y.R.
eLife 8
23 December 2019
The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.
Funk, N., Munz, M., Ott, T., Brockmann, K., Wenninger-Weinzierl, A., Kühn, R., Vogt-Weisenhorn, D., Giesert, F., Wurst, W., Gasser, T. and Biskup, S.
Scientific Reports 9
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14 March 2019
A benchmark for epithelial cell tracking.
Funke, J., Mais, L., Champion, A., Dye, N. and Kainmueller, D.
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23 January 2019
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Human stem cell models: lessons for pancreatic development and disease.
Gaertner, B., Carrano, A.C. and Sander, M.
Genes & Development 33
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1 November 2019
Supramolecular nanogels fabricated via host-guest molecular recognition as penetration enhancer for dermal drug delivery.
Gao, L., Zabihi, F., Ehrmann, S., Hedtrich, S. and Haag, R.
Journal of Controlled Release 300
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28 April 2019
Caloric restriction induces H(2)O(2) formation as a trigger of AMPK-eNOS-NO pathway in obese rats: role for CAMKII.
García-Prieto, C.F., Gil-Ortega, M., Plaza, A., Manzano-Lista, F.J., González-Blázquez, R., Alcalá, M., Rodríguez-Rodríguez, P., Viana, M., Aranguez, I., Gollasch, M., Somoza, B. and Fernández-Alfonso, M.S.
Free Radical Biology and Medicine 139
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1 August 2019
Association of intrathecal immunoglobulin G synthesis with disability worsening in multiple sclerosis.
Gasperi, C., Salmen, A., Antony, G., Bayas, A., Heesen, C., Kümpfel, T., Linker, R.A., Paul, F., Stangel, M., Tackenberg, B., Bergh, F.T., Warnke, C., Weber, F., Wiendl, H., Wildemann, B., Zettl, U.K., Ziemann, U., Zipp, F., Tumani, H., Gold, R. and Hemmer, B.
JAMA Neurology 76
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29 April 2019
Von konditionierten Ratten und gestressten Werktätigen: Rudolf Baumann und der Stress- und Umweltdiskurs in der DDR [On conditioned rats and stressed workmen: Rudolf Baumann and the discourse about stress and environment in the GDR].
Gausemeier, B.
NTM Zeitschrift für Geschichte der Wissenschaften, Technik und Medizin 27
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September 2019
The danger signal extracellular ATP is involved in the immunomediated damage of α-sarcoglycan-deficient muscular dystrophy.
Gazzerro, E., Baratto, S., Assereto, S., Baldassari, S., Panicucci, C., Raffaghello, L., Scudieri, P., De Battista, D., Fiorillo, C., Volpi, S., Chaabane, L., Malnati, M., Messina, G., Bruzzone, S., Traggiai, E., Grassi, F., Minetti, C. and Bruno, C.
American Journal of Pathology 189
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February 2019
Priming of LTP in amygdala and hippocampus by prior paired pulse facilitation paradigm in mice lacking brain serotonin.
Gebhardt, C., Mosienko, V., Alenina, N. and Albrecht, D.
Hippocampus 29
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July 2019
Suggestions for improving the design of clinical trials in multiple sclerosis - results of a systematic analysis of completed phase III trials.
Gehr, S., Kaiser, T., Kreutz, R., Ludwig, W.D. and Paul, F.
EPMA Journal 10
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December 2019
Were our critics right about the Stasi? AIDS disinformation and "disinformation squared" after five years.
Geissler, E. and Sprinkle, R.H.
Politics and the Life Sciences 38
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2019
ATTRACT: arterial flow as attractor for endothelial cell migration.
Georgieva, P.B., Marchuk, D.A. and Gerhardt, H.
Circulation Research 125
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July 2019
Olfactory and gustatory dysfunction in patients with autoimmune encephalitis.
Geran, R., Uecker, F.C., Prüss, H., Haeusler, K.G., Paul, F., Ruprecht, K., Harms, L. and Schmidt, F.A.
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May 2019
The genetic landscape of cardiomyopathies.
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Artery-vein specification in the zebrafish trunk is pre-patterned by heterogeneous Notch activity and balanced by flow-mediated fine tuning.
Geudens, I., Coxam, B., Alt, S., Gebala, V., Vion, A.C., Meier, K., Rosa, A. and Gerhardt, H.
Development 146
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27 August 2019
Towards depth-resolved characterization of hemodynamics and oxygenation in the rat kidney.
Gladytz, T., Cantow, K., Flemming, B., Pohlmann, A., Niendorf, T., Seeliger, E. and Grosenick, D.
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Near infrared spectroscopy system for quantitative monitoring of renal hemodynamics and oxygenation in rats.
Gladytz, T., Hoppe, A., Cantow, K., Flemming, B., Pohlmann, A., Niendorf, T., Seeliger, E. and Grosenick, D.
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1 March 2019
Advances and applications in the quest for orthologs.
Glover, N., Dessimoz, C., Ebersberger, I., Forslund, S.K., Gabaldón, T., Huerta-Cepas, J., Martin, M.J., Muffato, M., Patricio, M., Pereira, C., Sousa da Silva, A., Wang, Y., Sonnhammer, E. and Thomas, P.D.
Molecular Biology and Evolution 36
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October 2019
Sex differences in autoimmune disorders of the central nervous system.
Gold, S.M., Willing, A., Leypoldt, F., Paul, F. and Friese, M.A.
Seminars in Immunopathology 41
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March 2019
Maximal exercise and plasma cytochrome P450 and lipoxygenase mediators: a lipidomics study.
Gollasch, B., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 7
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August 2019
Maximal exercise and erythrocyte fatty-acid status: a lipidomics study.
Gollasch, B., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 7
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April 2019
Maximal exercise and erythrocyte epoxy fatty acids: a lipidomics study.
Gollasch, B., Wu, G., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 7
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November 2019
Evaluation des Medizinischen Praktischen Jahres (PJ) an der Charité - Universitätsmedizin Berlin [Project Report: Evaluation of the Practical Year (PY) at the Charité Medical School, University Medicine Berlin].
Gollasch, M., Kube, P., Danz, B., Arens, S. and Märdian, S.
Zeitschrift fuer Evidenz, Fortbildung und Qualitaet im Gesundheitswesen 141-142
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May 2019
HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M., Yu, Y., Liang, L., Vuralli, D., Froehler, S., Kuehnen, P., Du Bois, P., Zhang, J., Cao, A., Liu, Y., Hussain, K., Fielitz, J., Jia, S., Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7
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May 2019
Lung purinoceptor activation triggers ventilator-induced brain injury.
González-López, A., López-Alonso, I., Pickerodt, P.A., von Haefen, C., Amado-Rodríguez, L., Reimann, H., Niendorf, T., Kuebler, W., Albaiceta, G.M., Francis, R.C.E. and Spies, C.D.
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November 2019
Cellular senescence: defining a path forward.
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31 October 2019
An N-ethyl-N-nitrosourea (ENU)-induced Tyr265Stop mutation of the DNA polymerase accessory subunit gamma 2 (Polg2) is associated with renal calcification in mice.
Gorvin, C.M., Ahmad, B.N., Stechman, M.J., Loh, N.Y., Hough, T.A., Leo, P., Marshall, M., Sethi, S., Bentley, L., Piret, S.E., Reed, A., Jeyabalan, J., Christie, P.T., Wells, S., Simon, M.M., Mallon, A.M., Schulz, H., Huebner, N., Brown, M.A., Cox, R.D., Brown, S.D. and Thakker, R.V.
Journal of Bone and Mineral Research 34
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March 2019
Mice with a Brd4 mutation represent a new model of nephrocalcinosis.
Gorvin, C.M., Loh, N.Y., Stechman, M.J., Falcone, S., Hannan, F.M., Ahmad, B.N., Piret, S.E., Reed, A.A.C., Jeyabalan, J., Leo, P., Marshall, M., Sethi, S., Bass, P., Roberts, I., Sanderson, J., Wells, S., Hough, T.A., Bentley, L., Christie, P.T., Simon, M.M., Mallon, A.M., Schulz, H., Cox, R.D., Brown, M.A., Huebner, N., Brown, S.D. and Thakker, R.V.
Journal of Bone and Mineral Research 34
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July 2019
Ice-age climate adaptations trap the alpine marmot in a state of low genetic diversity.
Gossmann, T.I., Shanmugasundram, A., Börno, S., Duvaux, L., Lemaire, C., Kuhl, H., Klages, S., Roberts, L.D., Schade, S., Gostner, J.M., Hildebrand, F., Vowinckel, J., Bichet, C., Mülleder, M., Calvani, E., Zelezniak, A., Griffin, J.L., Bork, P., Allaine, D., Cohas, A., Welch, J.J., Timmermann, B. and Ralser, M.
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20 May 2019
Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis.
Graetz, C., Gröger, A., Luessi, F., Salmen, A., Zöller, D., Schultz, J., Siller, N., Fleischer, V., Bellenberg, B., Berthele, A., Biberacher, V., Havla, J., Hecker, M., Hohlfeld, R., Infante-Duarte, C., Kirschke, J.S., Kümpfel, T., Linker, R., Paul, F., Pfeuffer, S., Sämann, P., Toenges, G., Weber, F., Zettl, U.K., Jahn-Eimermacher, A., Antony, G., Groppa, S., Wiendl, H., Hemmer, B., Mühlau, M., Lukas, C., Gold, R., Lill, C.M. and Zipp, F.
Multiple Sclerosis Journal 25
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1 April 2019
sgRNA sequence motifs blocking efficient CRISPR/Cas9-mediated gene editing.
Graf, R., Li, X., Chu, V.T. and Rajewsky, K.
Cell Reports 26
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29 January 2019
BCR-dependent lineage plasticity in mature B cells.
Graf, R., Seagal, J., Otipoby, K.L., Lam, K.P., Ayoub, S., Zhang, B., Sander, S., Chu, V.T. and Rajewsky, K.
Science 363
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15 February 2019
Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk.
Greenwald, W.W., Chiou, J., Yan, J., Qiu, Y., Dai, N., Wang, A., Nariai, N., Aylward, A., Han, J.Y., Kadakia, N., Regue, L., Okino, M.L., Drees, F., Kramer, D., Vinckier, N., Minichiello, L., Gorkin, D., Avruch, J., Frazer, K.A., Sander, M., Ren, B. and Gaulton, K.J.
Nature Communications 10
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7 May 2019
Combined targeted resequencing of cytosine DNA methylation and mutations of DNA repair genes with potential use for poly(ADP-ribose) polymerase 1 inhibitor sensitivity testing.
Grimm, C., Fischer, A., Farrelly, A.M., Kalachand, R., Castiglione, R., Wasserburger, E., Hussong, M., Schultheis, Anne M, Altmüller, J., Thiele, H., Reinhardt, H.C., Hauschulz, K., Hennessy, B.T., Herwig, R., Lienhard, M., Buettner, R. and Schweiger, M.R.
Journal of Molecular Diagnostics 21
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March 2019
CD8(+) T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.
Gross, C.C., Meyer, C., Bhatia, U., Yshii, L., Kleffner, I., Bauer, J., Tröscher, A.R., Schulte-Mecklenbeck, A., Herich, S., Schneider-Hohendorf, T., Plate, H., Kuhlmann, T., Schwaninger, M., Brück, W., Pawlitzki, M., Laplaud, D.A., Loussouarn, D., Parratt, J., Barnett, M., Buckland, M.E., Hardy, T.A., Reddel, S.W., Ringelstein, M., Dörr, J., Wildemann, B., Kraemer, M., Lassmann, H., Höftberger, R., Beltrán, E., Dornmair, K., Schwab, N., Klotz, L., Meuth, S.G., Martin-Blondel, G., Wiendl, H. and Liblau, R.
Nature Communications 10
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18 December 2019
TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation.
Grund, A., Szaroszyk, M., Korf-Klingebiel, M., Malek Mohammadi, M., Trogisch, F.A., Schrameck, U., Gigina, A., Tiedje, C., Gaestel, M., Kraft, T., Hegermann, J., Batkai, S., Thum, T., Perrot, A., Remedios, C.D., Riechert, E., Völkers, M., Doroudgar, S., Jungmann, A., Bauer, R., Yin, X., Mayr, M., Wollert, K.C., Pich, A., Xiao, H., Katus, H.A., Bauersachs, J., Müller, O.J. and Heineke, J.
EMBO Molecular Medicine 11
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1 October 2019
Accurate assessment of LV function using the first automated 2D-border detection algorithm for small animals - evaluation and application to models of LV dysfunction.
Grune, J., Ritter, D., Kräker, K., Pappritz, K., Beyhoff, N., Schütte, T., Ott, C., John, C., van Linthout, S., Tschöpe, C., Dechend, R., Muller, D.N., Haase, N., Grune, T., Kintscher, U. and Kuebler, W.M.
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22 April 2019
Altered microRNA and target gene expression related to tetralogy of fallot.
Grunert, M., Appelt, S., Dunkel, I., Berger, F. and Sperling, S.R.
Scientific Reports 9
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13 December 2019
Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement.
Grushevskyi, E.O., Kukaj, T., Schmauder, R., Bock, A., Zabel, U., Schwabe, T., Benndorf, K. and Lohse, M.J.
Proceedings of the National Academy of Sciences of the United States of America 116
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14 May 2019
Serine protease mauritanicain from euphorbia mauritanica and phorbol-12-myristate-13-acetate modulate the IL-8 release in fibroblasts and HaCaT keratinocytes.
Guenther, F., Maus, D., Hedtrich, S. and Melzig, M.F.
Planta Medica 85
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May 2019
Interactions between carboxypeptidase M and kinin B1 receptor in endothelial cells.
Guimarães, P.B., da Silva, R.F., Hoff, C.C., Fernandes, L., Nakaie, C.R., Chagas, J.R., Karaoglanovic Carmona, A., Bader, M. and Pesquero, J.B.
Inflammation Research 68
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October 2019
Brain maturation is associated with increasing tissue stiffness and decreasing tissue fluidity.
Guo, J., Bertalan, G., Meierhofer, D., Klein, C., Schreyer, S., Steiner, B., Wang, S., Vieira da Silva, R., Infante-Duarte, C., Koch, S., Boehm-Sturm, P., Braun, J. and Sack, I.
Acta Biomaterialia 99
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November 2019
Quantitative proteome landscape of the NCI-60 cancer cell lines.
Guo, T., Luna, A., Rajapakse, V.N., Koh, C.C., Wu, Z., Liu, W., Sun, Y., Gao, H., Menden, M.P., Xu, C., Calzone, L., Martignetti, L., Auwerx, C., Buljan, M., Banaei-Esfahani, A., Ori, A., Iskar, M., Gillet, L., Bi, R., Zhang, J., Zhang, H., Yu, C., Zhong, Q., Varma, S., Schmitt, U., Qiu, P., Zhang, Q., Zhu, Y., Wild, P.J., Garnett, M.J., Bork, P., Beck, M., Liu, K., Saez-Rodriguez, J., Elloumi, F., Reinhold, W.C., Sander, C., Pommier, Y. and Aebersold, R.
iScience 21
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31 October 2019
Microglia/brain macrophages as central drivers of brain tumor pathobiology.
Gutmann, D.H. and Kettenmann, H.
Neuron 104
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6 November 2019
Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism.
Göppner, C., Orozco, I.J., Hoegg-Beiler, M.B., Soria, A.H., Hübner, C.A., Fernandes-Rosa, F.L., Boulkroun, S., Zennaro, M.C. and Jentsch, T.J.
Nature Communications 10
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15 October 2019
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Tenascin C regulates multiple microglial functions involving TLR4 signaling and HDAC1.
Haage, V., Elmadany, N., Roll, L., Faissner, A., Gutmann, D.H., Semtner, M. and Kettenmann, H.
Brain Behavior and Immunity 81
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October 2019
Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma.
Haage, V., Semtner, M., Oliveira Vidal, R., Perez Hernandez, D., Pong, W.W., Chen, Z., Hambardzumyan, D., Magrini, V., Ly, A., Walker, J., Mardis, E., Mertins, P., Sauer, S., Kettenmann, H. and Gutmann, D.H.
Acta Neuropathologica Communications 7
(1): 20.
14 February 2019
Sodium chloride triggers Th17 mediated autoimmunity.
Haase, S., Wilck, N., Kleinewietfeld, M., Müller, D.N. and Linker, R.A.
Journal of Neuroimmunology 329
: 9-13.
15 April 2019
Circulating MACC1 transcripts in glioblastoma patients predict prognosis and treatment response.
Hagemann, C., Neuhaus, N., Dahlmann, M., Kessler, A.F., Kobelt, D., Herrmann, P., Eyrich, M., Freitag, B., Linsenmann, T., Monoranu, C.M., Ernestus, R.I., Löhr, M. and Stein, U.
Cancers 11
(6): 825.
13 June 2019
MRG-1/MRG15 is a barrier for germ cell to neuron reprogramming in Caenorhabditis elegans.
Hajduskova, M., Baytek, G., Kolundzic, E., Gosdschan, A., Kazmierczak, M., Ofenbauer, A., Beato del Rosal, M.L., Herzog, S., ul Fatima, N., Mertins, P., Seelk-Müthel, S. and Tursun, B.
Genetics 211
(1): 121-139.
1 January 2019
3D high resolution imaging of human heart for visualization of the cardiac structure.
Haliot, K., Magat, J., Ozenne, V., Abell, E., Dubes, V., Bear, L., Gilbert, S.H., Trew, M.L., Haissaguerre, M., Quesson, B. and Bernus, O.
Lecture Notes in Computer Science 11504
: 196-207.
30 May 2019
Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.
Han, Y., Lindner, S., Bei, Y., Garcia, H.D., Timme, N., Althoff, K., Odersky, A., Schramm, A., Lissat, A., Künkele, A., Deubzer, H.E., Eggert, A., Schulte, J.H. and Henssen, A.G.
Cancer Letters 445
: 24-33.
31 March 2019
The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons.
Handara, G., Hetsch, F.J.A., Jüttner, R., Schick, A., Haupt, C., Rathjen, F.G. and Kröger, S.
Developmental Biology 445
(1): 54-67.
1 January 2019
GOPHER: Generator Of Probes for capture Hi-C Experiments at high Resolution.
Hansen, P., Ali, S., Blau, H., Danis, D., Hecht, J., Kornak, U., Lupiáñez, D.G., Mundlos, S., Steinhaus, R. and Robinson, P.N.
BMC Genomics 20
(1): 40.
14 January 2019
Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment.
Haremaki, T., Metzger, J.J., Rito, T., Ozair, M.Z., Etoc, F. and Brivanlou, A.H.
Nature Biotechnology 37
(10): 1198-1208.
October 2019
Parallel generation of easily selectable multiple nephronal cell types from human pluripotent stem cells.
Hariharan, K., Stachelscheid, H., Rossbach, B., Oh, S.J., Mah, N., Schmidt-Ott, K., Kurtz, A. and Reinke, P.
Cellular and Molecular Life Sciences 76
(1): 179-192.
January 2019
R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.
Harnack, C., Berger, H., Antanaviciute, A., Vidal, R., Sauer, S., Simmons, A., Meyer, T.F. and Sigal, M.
Nature Communications 10
(1): 4368.
25 September 2019
Escalation of memory length in finite populations.
Harrington, K. and Pollack, J.
Artificial Life 25
(1): 22-32.
2 April 2019
Mesothelial cell HIF1α expression is metabolically downregulated by metformin to prevent oncogenic tumor-stromal crosstalk.
Hart, P.C., Kenny, H.A., Grassl, N., Watters, K.M., Litchfield, L.M., Coscia, F., Blaženović, I., Ploetzky, L., Fiehn, O., Mann, M., Lengyel, E. and Romero, I.L.
Cell Reports 29
(12): 4086-4098.
17 December 2019
Criteria for surveys: from the European Association of Cardiovascular Imaging Scientific Initiatives Committee.
Haugaa, K.H., Marsan, N.A., Cameli, M., D'Andrea, A., Dweck, M.R., Carvalho, R.F., Holte, E., Manka, R., Michalski, B., Podlesnikar, T., Popescu, B.A., Schulz-Menger, J., Sitges, M., Stankovic, I., Maurer, G. and Edvardsen, T.
European Heart Journal - Cardiovascular Imaging 20
(9): 963-966.
September 2019
Deleterious somatic variants in 473 consecutive individuals with ovarian cancer: results of the observational AGO-TR1 study (NCT02222883).
Hauke, J., Hahnen, E., Schneider, S., Reuss, A., Richters, L., Kommoss, S., Heimbach, A., Marmé, F., Schmidt, S., Prieske, K., Gevensleben, H., Burges, A., Borde, J., De Gregorio, N., Nürnberg, P., El-Balat, A., Thiele, H., Hilpert, F., Altmüller, J., Meier, W., Dietrich, D., Kimmig, R., Schoemig-Markiefka, B., Kast, K., Braicu, E., Baumann, K., Jackisch, C., Park-Simon, T.W., Ernst, C., Hanker, L., Pfisterer, J., Schnelzer, A., du Bois, A., Schmutzler, R.K. and Harter, P.
Journal of Medical Genetics 56
(9): 574-580.
September 2019
Multiregion human bladder cancer sequencing reveals tumour evolution, bladder cancer phenotypes and implications for targeted therapy.
Heide, T., Maurer, A., Eipel, M., Knoll, K., Geelvink, M., Veeck, J., Knuechel, R., van Essen, J., Stoehr, R., Hartmann, A., Altmueller, J., Graham, T.A. and Gaisa, N.T.
Journal of Pathology 248
(2): 230-242.
June 2019
Structural features of tight-junction proteins.
Heinemann, U. and Schuetz, A.
International Journal of Molecular Sciences 20
(23): 6020.
29 November 2019
E47 modulates hepatic glucocorticoid action.
Hemmer, M.C., Wierer, M., Schachtrup, K., Downes, M., Hübner, N., Evans, R.M. and Uhlenhaut, N.H.
Nature Communications 10
(1): 306.
18 January 2019
Endothelial calcineurin signaling restrains metastatic outgrowth by regulating Bmp2.
Hendrikx, S., Coso, S., Prat-Luri, B., Wetterwald, L., Sabine, A., Franco, C.A., Nassiri, S., Zangger, N., Gerhardt, H., Delorenzi, M. and Petrova, T.V.
Cell Reports 26
(5): 1227-1241.
29 January 2019
Dietary protein restriction throughout intrauterine and postnatal life results in potentially beneficial myocardial tissue remodeling in the adult mouse heart.
Hennig, M., Ewering, L., Pyschny, S., Shimoyama, S., Olecka, M., Ewald, D., Magarin, M., Uebing, A., Thierfelder, L., Jux, C. and Drenckhahn, J.D.
Scientific Reports 9
(1): 15126.
22 October 2019
Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine.
Herberg, M., Siebert, S., Quaas, M., Thalheim, T., Rother, K., Hussong, M., Altmüller, J., Kerner, C., Galle, J., Schweiger, M.R. and Aust, G.
Clinical Epigenetics 11
(1): 65.
27 April 2019
Preclinical evaluation of a cell-based gene therapy using the Sleeping Beauty transposon system in choroidal neovascularization.
Hernandez, M., Recalde, S., Garcia-Garcia, L., Bezunartea, J., Miskey, C., Johnen, S., Diarra, S., Sebe, A., Rodriguez-Madoz, J.R., Pouillot, S., Marie, C., Izsvák, Z., Scherman, D., Kropp, M., Prosper, F., Thumann, G., Ivics, Z., Garcia-Layana, A. and Fernandez-Robredo, P.
Molecular Therapy - Methods and Clinical Development 15
: 403-417.
13 December 2019
Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.
Herrlinger, U., Tzaridis, T., Mack, F., Steinbach, J.P., Schlegel, U., Sabel, M., Hau, P., Kortmann, R.D., Krex, D., Grauer, O., Goldbrunner, R., Schnell, O., Bähr, O., Uhl, M., Seidel, C., Tabatabai, G., Kowalski, T., Ringel, F., Schmidt-Graf, F., Suchorska, B., Brehmer, S., Weyerbrock, A., Renovanz, M., Bullinger, L., Galldiks, N., Vajkoczy, P., Misch, M., Vatter, H., Stuplich, M., Schäfer, N., Kebir, S., Weller, J., Schaub, C., Stummer, W., Tonn, J.C., Simon, M., Keil, V.C., Nelles, M., Urbach, H., Coenen, M., Wick, W., Weller, M., Fimmers, R., Schmid, M., Hattingen, E., Pietsch, T., Coch, C. and Glas, M.
Lancet 393
(10172): 678-688.
16 February 2019
A C/EBPα-Wnt connection in gut homeostasis and carcinogenesis.
Heuberger, J., Hill, U., Förster, S., Zimmermann, K., Malchin, V., Kühl, A.A., Stein, U., Vieth, M., Birchmeier, W. and Leutz, A.
Life Science Alliance 2
(1): e201800173.
February 2019
Context-dependent signaling of CXC chemokine receptor 4
and atypical chemokine receptor 3.
Heuninck, J., Perpina Viciano, C., Işbilir, A., Caspar, B., Capoferri, D., Briddon, S.J., Durroux, T., Hill, S.J., Lohse, M.J., Milligan, G., Pin, J.P. and Hoffmann, C.
Molecular Pharmacology 96
(6): 778-793.
December 2019
Codon bias confers stability to human mRNAs.
Hia, F., Yang, S.F., Shichino, Y., Yoshinaga, M., Murakawa, Y., Vandenbon, A., Fukao, A., Fujiwara, T., Landthaler, M., Natsume, T., Adachi, S., Iwasaki, S. and Takeuchi, O.
EMBO Reports 20
(11): e48220.
5 November 2019
Sample preservation and storage significantly impact taxonomic and functional profiles in metaproteomics studies of the human gut microbiome.
Hickl, O., Heintz-Buschart, A., Trautwein-Schult, A., Hercog, R., Bork, P., Wilmes, P. and Becher, D.
Microorganisms 7
(9): 367.
19 September 2019
Antibiotics-induced monodominance of a novel gut bacterial order.
Hildebrand, F., Moitinho-Silva, L., Blasche, S., Jahn, M.T.T., Gossmann, T.I., Heuerta Cepas, J., Hercog, R., Luetge, M., Bahram, M., Pryszlak, A., Alves, R.J., Waszak, S.M., Zhu, A., Ye, L., Costea, P.I., Aalvink, S., Belzer, C., Forslund, S.K., Sunagawa, S., Hentschel, U., Merten, C., Patil, K.R., Benes, V. and Bork, P.
Gut 68
(10): 1781-1790.
9 September 2019
Regenerative potential of adipocytes in hypertrophic scars is mediated by myofibroblast reprogramming.
Hoerst, K., van den Broek, L., Sachse, C., Klein, O., von Fritschen, U., Gibbs, S. and Hedtrich, S.
Journal of Molecular Medicine 97
(6): 761-775.
1 June 2019
A synthetic epoxyeicosatrienoic acid analogue prevents the initiation of ischemic acute kidney injury.
Hoff, U., Bubalo, G., Fechner, M., Blum, M., Zhu, Y., Pohlmann, A., Hentschel, J., Arakelyan, K., Seeliger, E., Flemming, B., Gürgen, D., Rothe, M., Niendorf, T., Manthati, V.L., Falck, J.R., Haase, M., Schunck, W.H. and Dragun, D.
Acta Physiologica 227
(2): e13297.
October 2019
Autoantibodies activating the β2-adrenergic receptor characterize patients with primary and secondary glaucoma.
Hohberger, B., Kunze, R., Wallukat, G., Kara, K., Mardin, C.Y., Lämmer, R., Schlötzer-Schrehardt, U., Hosari, S., Horn, F., Munoz, L. and Herrmann, M.
Frontiers in Immunology 10
: 2112.
October 2019
RNA tomography for spatially resolved transcriptomics (Tomo-seq).
Holler, K. and Junker, J.P.
Methods in Molecular Biology 1920
: 129-141.
2019
Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial.
Horwitz, S., O'Connor, O.A., Pro, B., Illidge, T., Fanale, M., Advani, R., Bartlett, N.L., Christensen, J.H., Morschhauser, F., Domingo-Domenech, E., Rossi, G., Kim, W.S., Feldman, T., Lennard, A., Belada, D., Illés, A., Tobinai, K., Tsukasaki, K., Yeh, S.P., Shustov, A., Hüttmann, A., Savage, K.J., Yuen, S., Iyer, S., Zinzani, P.L., Hua, Z., Little, M., Rao, S., Woolery, J., Manley, T. and Trümper, L.
Lancet 393
(10168): 229-240.
19 January 2019
Genetics of intellectual disability in consanguineous families.
Hu, H., Kahrizi, K., Musante, L., Fattahi, Z., Herwig, R., Hosseini, M., Oppitz, C., Abedini, S.S., Suckow, V., Larti, F., Beheshtian, M., Lipkowitz, B., Akhtarkhavari, T., Mehvari, S., Otto, S., Mohseni, M., Arzhangi, S., Jamali, P., Mojahedi, F., Taghdiri, M., Papari, E., Soltani Banavandi, M.J., Akbari, S., Tonekaboni, S.H., Dehghani, H., Ebrahimpour, M.R., Bader, I., Davarnia, B., Cohen, M., Khodaei, H., Albrecht, B., Azimi, S., Zirn, B., Bastami, M., Wieczorek, D., Bahrami, G., Keleman, K., Vahid, L.N., Tzschach, A., Gärtner, J., Gillessen-Kaesbach, G., Varaghchi, J.R., Timmermann, B., Pourfatemi, F., Jankhah, A., Chen, W., Nikuei, P., Kalscheuer, V.M., Oladnabi, M., Wienker, T.F., Ropers, H.H. and Najmabadi, H.
Molecular Psychiatry 24
(7): 1027-1039.
July 2019
GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.
Hu, X., Matsumoto, K., Jung, R.S., Weston, T.A., Heizer, P.J., He, C., Sandoval, N.P., Allan, C.M., Tu, Y., Vinters, H.V., Liau, L.M., Ellison, R.M., Morales, J.E., Baufeld, L.J., Bayley, N.A., He, L., Betsholtz, C., Beigneux, A.P., Nathanson, D.A., Gerhardt, H., Young, S.G., Fong, L.G. and Jiang, H.
eLife 8
: e47178.
6 June 2019
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
Huang, A., Shinde, P.V., Huang, J., Senff, T., Xu, H.C., Margotta, C., Häussinger, D., Willnow, T.E., Zhang, J., Pandyra, A.A., Timm, J., Weggen, S., Lang, K.S. and Lang, P.A.
JCI Insight 4
(17): e129856.
5 September 2019
Vibrational spectroscopy as a powerful tool for follow-up immunoadsorption therapy treatment of dilated cardiomyopathy - a case report.
Huang, J., Ramoji, A., Guo, S., Bocklitz, T., Boivin-Jahns, V., Möller, J., Kiehntopf, M., Noutsias, M., Popp, J. and Neugebauer, U.
Analyst 145
(2): 486-496.
15 November 2019
Early hearing loss upon disruption of Slc4a10 in C57BL/6 mice.
Huebner, A.K., Maier, H., Maul, A., Nietzsche, S., Herrmann, T., Praetorius, J. and Hübner, C.A.
Journal of the Association for Research in Otolaryngology 20
(3): 233-245.
June 2019
eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses.
Huerta-Cepas, J., Szklarczyk, D., Heller, D., Hernández-Plaza, A., Forslund, S.K., Cook, H., Mende, D.R., Letunic, I., Rattei, T., Jensen, L.J., von Mering, C. and Bork, P.
Nucleic Acids Research 47
(D1): D309-D314.
8 January 2019
Targeting the tumor microenvironment of leukemia and lymphoma.
Höpken, U.E. and Rehm, A.
Trends in Cancer 5
(6): 351-364.
June 2019
BigStitcher: reconstructing high-resolution image datasets of cleared and expanded samples.
Hörl, D., Rojas Rusak, F., Preusser, F., Tillberg, P., Randel, N., Chhetri, R.K., Cardona, A., Keller, P.J., Harz, H., Leonhardt, H., Treier, M. and Preibisch, S.
Nature Methods 16
(9): 870-874.
September 2019
I
Live-imaging readouts and cell models for phenotypic profiling of mitochondrial function.
Iannetti, E.F., Prigione, A., Smeitink, J.A.M., Koopman, W.J.H., Beyrath, J. and Renkema, H.
Frontiers in Genetics 10
: 131.
March 2019
Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifications.
Ibarra Urizar, A., Prause, M., Wortham, M., Sui, Y., Thams, P., Sander, M., Christensen, G.L. and Billestrup, N.
Molecular and Cellular Endocrinology 496
: 110524.
1 October 2019
Discontinuous shear-thinning in adhesive dispersions.
Irani, E., Chaudhuri, P. and Heussinger, C.
Physical Review Fluids 4
(7): 074307.
18 July 2019
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Evaluation of a rare glucose-dependent insulinotropic polypeptide receptor variant in a patient with diabetes.
Jacobi, S.F., Khajavi, N., Kleinau, G., Teumer, A., Scheerer, P., Homuth, G., Völzke, H., Wiegand, S., Kühnen, P., Krude, H., Gong, M., Raile, K. and Biebermann, H.
Diabetes Obesity and Metabolism 21
(5): 1168-1176.
May 2019
Multiple sclerosis-related fatigue: altered resting-state functional connectivity of the ventral striatum and dorsolateral prefrontal cortex.
Jaeger, S., Paul, F., Scheel, M., Brandt, A., Heine, J., Pach, D., Witt, C.M., Bellmann-Strobl, J. and Finke, C.
Multiple Sclerosis Journal 25
(4): 554-564.
April 2019
A combined miRNA-piRNA signature to detect Alzheimer's disease.
Jain, G., Stuendl, A., Rao, P., Berulava, T., Pena Centeno, T., Kaurani, L., Burkhardt, S., Delalle, I., Kornhuber, J., Hüll, M., Maier, W., Peters, O., Esselmann, H., Schulte, C., Deuschle, C., Synofzik, M., Wiltfang, J., Mollenhauer, B., Maetzler, W., Schneider, A. and Fischer, A.
Translational Psychiatry 9
(1): 250.
7 October 2019
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML.
Jakobsen, J.S., Laursen, L.G., Schuster, M.B., Pundhir, S., Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mönch, K., Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. and Porse, B.T.
Science Advances 5
(7): eaaw4304.
July 2019
Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia.
James, A.R., Schroeder, M.P., Neumann, M., Bastian, L., Eckert, C., Gökbuget, N., Tanchez, J.O., Schlee, C., Isaakidis, K., Schwartz, S., Burmeister, T., von Stackelberg, A., Rieger, M.A., Göllner, S., Horstman, M., Schrappe, M., Kirschner-Schwabe, R., Brüggemann, M., Müller-Tidow, C., Serve, H., Akalin, A. and Baldus, C.D.
Journal of Hematology & Oncology 12
(1): 8.
14 January 2019
Fabrication of kidney proximal tubule grafts using biofunctionalized electrospun polymer scaffolds.
Jansen, K., Castilho, M., Aarts, S., Kaminski, M.M., Lienkamp, S.S., Pichler, R., Malda, J., Vermonden, T., Jansen, J. and Masereeuw, R.
Macromolecular Bioscience 19
(2): e1800412.
February 2019
Myelinoclastic diffuse sclerosis (Schilder's disease) is immunologically distinct from multiple sclerosis: results from retrospective analysis of 92 lumbar punctures.
Jarius, S., Haas, J., Paul, F. and Wildemann, B.
Journal of Neuroinflammation 16
(1): 51.
28 February 2019
A network of microRNAs acts to promote cell cycle exit and differentiation of human pancreatic endocrine cells.
Jin, W., Mulas, F., Gaertner, B., Sui, Y., Wang, J., Matta, I., Zeng, C., Vinckier, N., Wang, A., Nguyen-Ngoc, K.V., Chiou, J., Kaestner, K.H., Frazer, K.A., Carrano, A.C., Shih, H.P. and Sander, M.
iScience 21
: 681-694.
22 November 2019
Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress.
Jochner, M.C.E., An, J., Lättig-Tünnemann, G., Kirchner, M., Dagane, A., Dittmar, G., Dirnagl, U., Eickholt, B.J. and Harms, C.
Scientific Reports 9
(1): 3183.
28 February 2019
Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS).
Johnen, A., Bürkner, P.C., Landmeyer, N.C., Ambrosius, B., Calabrese, P., Motte, J., Hessler, N., Antony, G., König, I.R., Klotz, L., Hoshi, M.M., Aly, L., Groppa, S., Luessi, F., Paul, F., Tackenberg, B., Bergh, F.T., Kümpfel, T., Tumani, H., Stangel, M., Weber, F., Bayas, A., Wildemann, B., Heesen, C., Zettl, U.K., Zipp, F., Hemmer, B., Meuth, S.G., Gold, R., Wiendl, H. and Salmen, A.
Journal of Neurology 266
(2): 386-397.
February 2019
Lymphocyte characterization of decidua basalis spiral arteries with acute atherosis in preeclamptic and normotensive pregnancies.
Johnsen, G.M., Størvold, G.L., Alnaes-Katjavivi, P.H., Roald, B., Golic, M., Dechend, R., Redman, C.W.G. and Staff, A.C.
Journal of Reproductive Immunology 132
: 42-48.
April 2019
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Joshi, K., de Massy, M.R., Ismail, M., Reading, J.L., Uddin, I., Woolston, A., Hatipoglu, E., Oakes, T., Rosenthal, R., Peacock, T., Ronel, T., Noursadeghi, M., Turati, V., Furness, A.J.S., Georgiou, A., Wong, Y.N.S., Ben Aissa, A., Sunderland, M.W., Jamal-Hanjani, M., Veeriah, S., Birkbak, N.J., Wilson, G.A., Hiley, C.T., Ghorani, E., Guerra-Assunção, J.A., Herrero, J., Enver, T., Hadrup, S.R., Hackshaw, A., Peggs, K.S., McGranahan, N., Swanton, C., Quezada, S.A. and Chain, B.
Nature Medicine 25
(10): 1549-1559.
October 2019
Multiple two-photon targeted whole-cell patch-clamp recordings from monosynaptically connected neurons in vivo.
Jouhanneau, J.S. and Poulet, J.F.A.
Frontiers in Synaptic Neuroscience 11
: 15.
May 2019
In vivo-mimicking microfluidic perfusion culture of pancreatic islet spheroids.
Jun, Y., Lee, J.S., Choi, S., Yang, J.H., Sander, M., Chung, S. and Lee, S.H.
Science Advances 5
(11): eaax4520.
1 November 2019
Detouring the roadblocks in gene expression.
Junker, J.P.
Nature Reviews Molecular Cell Biology 20
(4): 197.
April 2019
Human gestational N-methyl-d-aspartate receptor autoantibodies impair neonatal murine brain function.
Jurek, B., Chayka, M., Kreye, J., Lang, K., Kraus, L., Fidzinski, P., Kornau, H.C., Dao, L.M., Wenke, N.K., Long, M., Rivalan, M., Winter, Y., Leubner, J., Herken, J., Mayer, S., Mueller, S., Boehm-Sturm, P., Dirnagl, U., Schmitz, D., Kölch, M. and Prüss, H.
Annals of Neurology 86
(5): 656-670.
November 2019
SSBP1 mutations in dominant optic atrophy with variable retinal degeneration.
Jurkute, N., Leu, C., Pogoda, H.M., Arno, G., Robson, A.G., Nürnberg, G., Altmüller, J., Thiele, H., Motameny, S., Toliat, M.R., Powell, K., Höhne, W., Michaelides, M., Webster, A.R., Moore, A.T., Hammerschmidt, M., Nürnberg, P., Yu-Wai-Man, P. and Votruba, M.
Annals of Neurology 86
(3): 368-383.
September 2019
Immunhistochemische Analyse von Bcl-2, nukleärem S100A4, MITF und Ki67 zur Risikostratifizierung von Melanomen im Frühstadium - ein kombinierter immunhistochemischer Score.
Jurmeister, P., Bockmayr, M., Treese, C., Stein, U., Lenze, D., Jöhrens, K., Friedling, F., Dietel, M., Klauschen, F., Marsch, W., Fiedler, E. and von Laffert, M.
Journal der Deutschen Dermatologischen Gesellschaft 17
(8): 800-809.
August 2019
Immunohistochemical analysis of Bcl-2, nuclear S100A4, MITF and Ki67 for risk stratification of early-stage melanoma - a combined IHC score for melanoma risk stratification.
Jurmeister, P., Bockmayr, M., Treese, C., Stein, U., Lenze, D., Jöhrens, K., Friedling, F., Dietel, M., Klauschen, F., Marsch, W., Fiedler, E. and von Laffert, M.
Journal der Deutschen Dermatologischen Gesellschaft 17
(8): 800-808.
August 2019
Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations.
Jutzi, J.S., Basu, T., Pellmann, M., Kaiser, S., Steinemann, D., Sanders, M.A., Hinai, A.S.A., Zeilemaker, A., Bojtine Kovacs, S., Koellerer, C., Ostendorp, J., Aumann, K., Wang, W., Raffoux, E., Cassinat, B., Bullinger, L., Schlegelberger, B., Valk, P.J.M. and Pahl, H.L.
Blood 133
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18 April 2019
Angiotensin-(1-7) receptor Mas in hemodynamic and thermoregulatory dysfunction after high-level spinal cord injury in mice: a pilot study.
Järve, A., Todiras, M., Kny, M., Fischer, F.I., Kraemer, J.F., Wessel, N., Plehm, R., Fielitz, J., Alenina, N. and Bader, M.
Frontiers in Physiology 9
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January 2019
Distinct roles of angiotensin receptors in autonomic dysreflexia following high-level spinal cord injury in mice.
Järve, A., Todiras, M., Lian, X, Filippelli-Silva, R., Qadri, F., Martin, R.P., Gollasch, M. and Bader, M.
Experimental Neurology 311
: 173-181.
January 2019
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Cytotoxic effects of rabbit anti-thymocyte globulin preparations on primary human thymic epithelial cells.
Kaebisch, E.M., Cho, M.Y., Oh, Y.S., Olfe, L.I., Szyska, M., Becker, S.C., Reinke, P., Volk, H.D., Gillissen, B., Bullinger, L., Thiel, A. and Na, I.K.
Transplantation 103
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November 2019
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors.
Kaffes, I., Szulzewsky, F., Chen, Z., Herting, C.J., Gabanic, B., Velázquez Vega, J.E., Shelton, J., Switchenko, J.M., Ross, J.L., McSwain, L.F., Huse, J.T., Westermark, B., Nelander, S., Forsberg-Nilsson, K., Uhrbom, L., Maturi, N.P., Cimino, P.J., Holland, E.C., Kettenmann, H., Brennan, C.W., Brat, D.J. and Hambardzumyan, D.
OncoImmunology 8
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22 August 2019
Nanocapsule induced morphology and migration changes in single cell layers quantified with digital holographic microscopy.
Kaiser, M., Pohl, L., Ketelhut, S., Kastl, L., Gorzelanny, C., Götte, M., Schnekenburger, J., Goycoolea, F.M. and Kemper, B.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
4 March 2019
Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ.
Kalasova, I., Hanzlikova, H., Gupta, N., Li, Y., Altmüller, J., Reynolds, J.J., Stewart, G.S., Wollnik, B., Yigit, G. and Caldecott, K.W.
Neurology Genetics 5
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April 2019
Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined.
Kaleviste, E., Saare, M., Leahy, T.R., Bondet, V., Duffy, D., Mogensen, T., Jørgensen, S.E., Nurm, H., Ip, W., Davies, E.G., Sauer, S., Syvänen, A.C., Milani, L., Peterson, P. and Kisand, K.
European Journal of Immunology 49
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May 2019
Left prefrontal high-frequency rTMS may improve movement disorder in schizophrenia patients with predominant negative symptoms - a secondary analysis of a sham-controlled, randomized multicenter trial.
Kamp, D., Engelke, C., Wobrock, T., Wölwer, W., Winterer, G., Schmidt-Kraepelin, C., Gaebel, W., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Raees, A., Honer, W.G., Malchow, B., Schneider-Axmann, T., Falkai, P., Hasan, A. and Cordes, J.
Schizophrenia Research 204
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February 2019
Hypertonicity-affected genes are differentially expressed in clear cell renal cell carcinoma and correlate with cancer-specific survival.
Kandabarau, S., Leiz, J., Krohn, K., Winter, S., Bedke, J., Schwab, M., Schaeffeler, E. and Edemir, B.
Cancers 12
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18 December 2019
The association between frailty and MRI features of cerebral small vessel disease.
Kant, I.M.J., Mutsaerts, H.J.M.M., van Montfort, S.J.T., Jaarsma-Coes, M.G., Witkamp, T.D., Winterer, G., Spies, C.D., Hendrikse, J., Slooter, A.J.C. and de Bresser, J.
Scientific Reports 9
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5 August 2019
Mathematical modeling of semiconductors: from quantum mechanics to devices.
Kantner, M., Mielke, A., Mittnenzweig, M. and Rotundo, N.
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28 November 2019
MTrack: automated detection, tracking, and analysis of dynamic microtubules.
Kapoor, V., Hirst, W.G., Hentschel, C., Preibisch, S. and Reber, S.
Scientific Reports 9
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7 March 2019
Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling.
Karabacak Calviello, A., Hirsekorn, A., Wurmus, R., Yusuf, D. and Ohler, U.
Genome Biology 20
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21 February 2019
Biallelic variant in AGTPBP1 causes infantile lower motor neuron degeneration and cerebellar atrophy.
Karakaya, M., Paketci, C., Altmueller, J., Thiele, H., Hoelker, I., Yis, U. and Wirth, B.
American Journal of Medical Genetics Part A 179
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August 2019
Recruitment of histone methyltransferase Ehmt1 to Foxp3 TSDR counteracts differentiation of induced regulatory T cells.
Karl, M., Sommer, C., Gabriel, C.H., Hecklau, K., Venzke, M., Hennig, A.F., Radbruch, A., Selbach, M. and Baumgrass, R.
Journal of Molecular Biology 431
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6 September 2019
Lyophilization of synthetic gene carriers.
Kasper, J.C., Hedtrich, S. and Friess, W.
Methods in Molecular Biology 1943
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2019
Vinylphosphonites for staudinger-induced chemoselective peptide cyclization and functionalization.
Kasper, M.A, Glanz, M., Oder, A., Schmieder, P., von Kries, J.P. and Hackenberger, C.P.R.
Chemical Science 10
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7 July 2019
Automatic quality evaluation as assessment standard for optical coherence tomography.
Kauer, J., Gawlik, K., Zimmermann, H.G., Kadas, E.M., Bereuter, C., Paul, F., Brandt, A.U., Hausser, F. and Beckers, I.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, United States.
26 February 2019
Impact of brief prewarming on anesthesia-related core-temperature drop, hemodynamics, microperfusion and postoperative ventilation in cytoreductive surgery of ovarian cancer: a randomized trial.
Kaufner, L., Niggemann, P., Baum, T., Casu, S., Sehouli, J., Bietenbeck, A., Boschmann, M., Spies, C.D., Henkelmann, A. and von Heymann, C.
BMC Anesthesiology 19
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22 August 2019
HSPA6: s new autosomal recessive candidate gene for the VATER/VACTERL malformation spectrum.
Kause, F., Zhang, R., Ludwig, M., Schmiedeke, E., Rissmann, A., Thiele, H., Altmueller, J., Herms, S., Hilger, A.C., Hildebrandt, F. and Reutter, H.
Birth Defects Research 111
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1 June 2019
Role of ryanodine type 2 receptors in elementary Ca(2+) signaling in arteries and vascular adaptive responses.
Kaßmann, M., Szijártó, I.A., García-Prieto, C.F., Fan, G., Schleifenbaum, J., Anistan, Y.M., Tabeling, C., Shi, Y., le Noble, F., Witzenrath, M., Huang, Y., Markó, L., Nelson, M.T. and Gollasch, M.
Journal of the American Heart Association 8
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7 May 2019
Systems biology approach to study cancer metabolism.
Kempa, S. and Royla, N.
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Quantitative phase imaging-based concepts for the analysis of global morphology changes in confluent cell layers.
Kemper, B., Pohl, L., Kaiser, M., Doepker, E., Schnekenburger, J. and Ketelhut, S.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
4 March 2019
Label-free detection of global morphology changes in confluent cell layers utilizing quantitative phase imaging with digital holographic microscopy.
Kemper, B., Pohl, L., Kaiser, M., Döpker, E., Schnekenburger, J. and Ketelhut, S.
In: European Conferences on Biomedical Optics 2019, 26-27 Jun 2019, Munich, Germany.
22 July 2019
Hyperkaliämie - Ursachen, Diagnostik und Therapie [Hyperkalemia - causes, diagnostic evaluation and treatment].
Kettritz, R.
Deutsche Medizinische Wochenschrift 144
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February 2019
Seltene Elektrolytstörungen [Rare electrolyte disorders].
Kettritz, R. and Luft, F.C.
Nephrologe 14
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March 2019
The incidence of acute kidney injury and associated hospital mortality: a retrospective cohort study of over 100 000 patients at Berlin's Charité Hospital.
Khadzhynov, D., Schmidt, D., Hardt, J., Rauch, G., Gocke, P., Eckardt, K.U. and Schmidt-Ott, K.M.
Deutsches Aerzteblatt International 116
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31 May 2019
Histological and functional comparisons of four anatomical regions of porcine skin with human abdominal skin.
Khiao In, M., Richardson, K.C., Loewa, A., Hedtrich, S., Kaessmeyer, S. and Plendl, J.
Anatomia Histologia Embryologia 48
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May 2019
Disruption of PHF21A causes syndromic intellectual disability with craniofacial anomalies, epilepsy, hypotonia, and neurobehavioral problems including autism.
Kim, H.G., Rosenfeld, J.A., Scott, D.A., Bénédicte, G., Labonne, J.D., Brown, J., McGuire, M., Mahida, S., Naidu, S., Gutierrez, J., Lesca, G., des Portes, V., Bruel, A.L., Sorlin, A., Xia, F., Capri, Y., Muller, E., McKnight, D., Torti, E., Rüschendorf, F., Hummel, O., Islam, Z., Kolatkar, P.R., Layman, L.C., Ryu, D., Kong, I.K., Madan-Khetarpal, S. and Kim, C.H.
Molecular Autism 10
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22 October 2019
Biobanking for metabolomics and lipidomics in precision medicine.
Kirwan, J.A., Kaddurah-Daouk, R., Mitchell, T., Pischon, T., Schmidt, M.A. and Velagapudi, V.
Clinical Chemistry 65
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28 June 2019
A protocol for laser microdissection (LMD) followed by transcriptome analysis of plant reproductive tissue in phylogenetically distant angiosperms.
Kivivirta, K., Herbert, D., Lange, M., Beuerlein, K., Altmüller, J. and Becker, A.
Plant Methods 15
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16 December 2019
Quantitative grip force assessment of muscular weakness in chronic inflammatory demyelinating polyneuropathy.
Klehmet, J., Beutner, S., Hoffmann, S., Dornauer, M., Paul, F., Reilmann, R., Brandt, A.U. and Meisel, A.
BMC Neurology 19
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8 June 2019
TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor.
Klein, S., Kleine, C.E., Pieper, A., Granzow, M., Gautsch, S., Himmit, M., Kahrmann, K., Schierwagen, R., Uschner, F.E., Magdaleno, F., Naoum, M.E., Kristiansen, Glen, Walther, T., Bader, M., Sauerbruch, T. and Trebicka, J.
Scientific Reports 9
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12 August 2019
Dynamics of chromatin and transcription during transient depletion of the RSC chromatin remodeling complex.
Klein-Brill, A., Joseph-Strauss, D., Appleboim, A. and Friedman, N.
Cell Reports 26
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2 January 2019
Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB/W F1 mice.
Klocke, J., Ulu, A., Wu, K., Rudolph, B., Dragun, D., Gollasch, M., Schunck, W.H., Hammock, B.D., Riemekasten, G. and Enghard, P.
Scientific Reports 9
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20 June 2019
m(6)A-mRNA methylation regulates cardiac gene expression and cellular growth.
Kmietczyk, V., Riechert, E., Kalinski, L., Boileau, E., Malovrh, E., Malone, B., Gorska, A., Hofmann, C., Varma, E., Jürgensen, L., Kamuf-Schenk, V., Altmüller, J., Tappu, R., Busch, M., Most, P., Katus, H.A., Dieterich, C. and Völkers, M.
Life Science Alliance 2
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April 2019
Interferon-γ receptor signaling in dendritic cells restrains spontaneous proliferation of CD4(+) T cells in chronic lymphopenic mice.
Knop, L., Frommer, C., Stoycheva, D., Deiser, K., Kalinke, U., Blankenstein, T., Kammertoens, T., Dunay, I.R. and Schüler, T.
Frontiers in Immunology 10
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7 February 2019
Ninjurin1 regulates striated muscle growth and differentiation.
Kny, M., Csályi, K.D., Klaeske, K., Busch, K., Meyer, A.M., Merks, A.M., Darm, K., Dworatzek, E., Fliegner, D., Baczko, I., Regitz-Zagrosek, V., Butter, C., Luft, F.C., Panáková, D. and Fielitz, J.
PLoS ONE 14
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15 May 2019
Design and characterization of dietary assessment in the German National Cohort.
Knüppel, S., Clemens, M., Conrad, J., Gastell, S., Michels, K.B., Leitzmann, M., Krist, L., Pischon, T., Krause, G., Ahrens, W., Ebert, N., Jöckel, K.H., Kluttig, A., Obi, N., Kaaks, R., Lieb, W., Schipf, S., Brenner, H., Heuer, T., Harttig, U., Linseisen, J., Nöthlings, U. and Boeing, H.
European Journal of Clinical Nutrition 73
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November 2019
Cognitive impairment is associated with absolute intraoperative frontal α-band power but not with baseline α-band power: a pilot study.
Koch, S., Feinkohl, I., Chakravarty, S., Windmann, V., Lichtner, G., Pischon, T., Brown, E.N. and Spies, C.
Dementia and Geriatric Cognitive Disorders 48
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December 2019
Biallelic mutation in MYH7 and MYBPC3 leads to severe cardiomyopathy with left ventricular noncompaction phenotype.
Kolokotronis, K., Kühnisch, J., Klopocki, E., Dartsch, J., Rost, S., Huculak, C., Mearini, G., Störk, S., Carrier, L., Klaassen, S. and Gerull, B.
Human Mutation 40
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August 2019
Rare variants in BNC2 are implicated in autosomal-dominant congenital lower urinary-tract obstruction.
Kolvenbach, C.M., Dworschak, G.C., Frese, S., Japp, A.S., Schuster, P., Wenzlitschke, N., Yilmaz, Ö., Lopes, F.M., Pryalukhin, A., Schierbaum, L., van der Zanden, L.F.M., Kause, F., Schneider, R., Taranta-Janusz, K., Szczepańska, M., Pawlaczyk, K., Newman, W.G., Beaman, G.M., Stuart, H.M., Cervellione, R.M., Feitz, W.F.J., van Rooij, I.A.L.M., Schreuder, M.F., Steffens, M., Weber, S., Merz, W.M., Feldkötter, M., Hoppe, B., Thiele, H., Altmüller, J., Berg, C., Kristiansen, G., Ludwig, M., Reutter, H., Woolf, A.S., Hildebrandt, F., Grote, P., Zaniew, M., Odermatt, B. and Hilger, A.C.
American Journal of Human Genetics 104
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2 May 2019
Renal fibrosis, immune cell infiltration and changes of TRPC channel expression after unilateral ureteral obstruction in Trpc6-/- mice.
Kong, W., Haschler, T.N., Nürnberg, B., Krämer, S., Gollasch, M. and Markó, L.
Cellular Physiology and Biochemistry 52
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2019
Prediction of circulating adipokine levels based on body fat compartments and adipose tissue gene expression.
Konigorski, S., Janke, J., Drogan, D., Bergmann, M.M., Hierholzer, J., Kaaks, R., Boeing, H. and Pischon, T.
Obesity Facts 12
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December 2019
The ARTS of cell death.
Koren, E. and Fuchs, Y.
Journal of Cell Death 12
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1 January 2019
Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses.
Kosciuczuk, E.M., Mehrotra, S., Saleiro, D., Kroczynska, B., Majchrzak-Kita, B., Lisowski, P., Driehaus, C., Rogalska, A., Turner, A., Lienhoop, T., Gius, D., Fish, E.N., Vassilopoulos, A. and Platanias, L.C.
Journal of Biological Chemistry 294
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18 January 2019
MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis.
Kotelnikova, E., Kiani, N.A., Messinis, D., Pertsovskaya, I., Pliaka, V., Bernardo-Faura, M., Rinas, M., Vila, G., Zubizarreta, I., Pulido-Valdeolivas, I., Sakellaropoulos, T., Faigle, W., Silberberg, G., Masso, M., Stridh, P., Behrens, J., Olsson, T., Martin, R., Paul, F., Alexopoulos, L.G., Saez-Rodriguez, J., Tegner, J. and Villoslada, P.
Proceedings of the National Academy of Sciences of the United States of America 116
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7 May 2019
Chaperone protein HSC70 regulates intercellular transfer of Y chromosome antigen DBY.
Kretschmann, S., Herda, S., Bruns, H., Russ, J., van der Meijden, E.D., Schlötzer-Schrehardt, U., Griffioen, M., Na, I.K., Mackensen, A. and Kremer, A.N.
Journal of Clinical Investigation 129
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1 July 2019
Less is more - estimation of the number of strides required to assess gait variability in spatially confined settings.
Kroneberg, D., Elshehabi, M., Meyer, A.C., Otte, K., Doss, S., Paul, F., Nussbaum, S., Berg, D., Kühn, A.A., Maetzler, W. and Schmitz-Hübsch, T.
Frontiers in Aging Neuroscience 10
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21 January 2019
A curated resource for phosphosite-specific signature analysis.
Krug, K., Mertins, P., Zhang, B., Hornbeck, P., Raju, R., Ahmad, R., Szucs, M., Mundt, F., Forestier, D., Jane-Valbuena, J., Keshishian, H., Gillette, M.A., Tamayo, P., Mesirov, J.P., Jaffe, J.D., Carr, S.A. and Mani, D.R.
Molecular & Cellular Proteomics 18
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1 March 2019
AltamISA: a Python API for ISA-Tab files.
Kuhring, M., Nieminen, M., Kirwan, J., Beule, D. and Holtgrewe, M.
Journal of Open Source Software 4
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20 August 2019
Cardiac magnetic resonance stress perfusion imaging for evaluation of patients with chest pain.
Kwong, R.Y., Ge, Y., Steel, K., Bingham, S., Abdullah, S., Fujikura, K., Wang, W., Pandya, A., Chen, Y.Y., Mikolich, J.R., Boland, S., Arai, A.E., Bandettini, W.P., Shanbhag, S.M., Patel, A.R., Narang, A., Farzaneh-Far, A., Romer, B., Heitner, J.F., Ho, J.Y., Singh, J., Shenoy, C., Hughes, A., Leung, S.W., Marji, M., Gonzalez, J.A., Mehta, S., Shah, D.J., Debs, D., Raman, S.V., Guha, A., Ferrari, V.A., Schulz-Menger, J., Hachamovitch, R., Stuber, M. and Simonetti, O.P.
Journal of the American College of Cardiology 74
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8 October 2019
Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3.
Kühnisch, J., Herbst, C., Al-Wakeel-Marquard, N., Dartsch, J., Holtgrewe, M., Baban, A., Mearini, G., Hardt, J., Kolokotronis, K., Gerull, B., Carrier, L., Beule, D., Schubert, S., Messroghli, D., Degener, F., Berger, F. and Klaassen, S.
Clinical Genetics 96
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December 2019
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Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.
LaBranche, C.C., Henderson, R., Hsu, A., Behrens, S., Chen, X., Zhou, T., Wiehe, K., Saunders, K.O., Alam, S.M., Bonsignori, M., Borgnia, M.J., Sattentau, Q.J., Eaton, A., Greene, K., Gao, H., Liao, H.X., Williams, W.B., Peacock, J., Tang, H., Perez, L.G., Edwards, R.J., Kepler, T.B., Korber, B.T., Kwong, P.D., Mascola, J.R., Acharya, P., Haynes, B.F. and Montefiori, D.C.
PLoS Pathogens 15
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17 September 2019
Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat.
Labi, V., Peng, S., Klironomos, F., Munschauer, M., Kastelic, N., Chakraborty, T., Schoeler, K., Derudder, E., Martella, M., Mastrobuoni, G., Hernandez-Miranda, L.R., Lahmann, I., Kocks, C., Birchmeier, C., Kempa, S., Quintanilla-Martinez de Fend, L., Landthaler, M., Rajewsky, N. and Rajewsky, K.
Genes & Development 33
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7 November 2019
Cerebral microbleeds are not associated with postoperative delirium and postoperative cognitive dysfunction in older individuals.
Lachmann, G., Kant, I., Lammers, F., Windmann, V., Spies, C., Speidel, S., Borchers, F., Hadzidiakos, D., Hendrikse, J., Winterer, G. and de Bresser, J.
PLoS ONE 14
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14 June 2019
The accumulation of deficits approach to describe frailty.
Lachmann, R., Stelmach-Mardas, M., Bergmann, M.M., Bernigau, W., Weber, D., Pischon, T. and Boeing, H.
PLoS ONE 14
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15 October 2019
Impact of diabetic stress conditions on renal cell metabolome.
Lagies, S., Pichler, R., Bork, T., Kaminski, M.M., Troendle, K., Zimmermann, S., Huber, T.B., Walz, G., Lienkamp, S.S. and Kammerer, B.
Cells 8
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24 September 2019
Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells.
Lahmann, I., Bröhl, D., Zyrianova, T., Isomura, A., Czajkowski, M.T., Kapoor, V., Griger, J., Ruffault, P.L., Mademtzoglou, D., Zammit, P.S., Wunderlich, T., Spuler, S., Kühn, R., Preibisch, S., Wolf, J., Kageyama, R. and Birchmeier, C.
Genes & Development 33
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1 May 2019
Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly.
Lahrouchi, N., George, A., Ratbi, I., Schneider, R., Elalaoui, S.C., Moosa, S., Bharti, S., Sharma, R., Abu-Asab, M., Onojafe, F., Adadi, N., Lodder, E.M., Laarabi, F.Z., Lamsyah, Y., Elorch, H., Chebbar, I., Postma, A.V., Lougaris, V., Plebani, A., Altmueller, J., Kyrieleis, H., Meiner, V., McNeill, H., Bharti, K., Lyonnet, S., Wollnik, B., Henrion-Caude, A., Berraho, A., Hildebrandt, F., Bezzina, C.R., Brooks, B.P. and Sefiani, A.
Nature Communications 10
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12 March 2019
Collagen I-based scaffolds negatively impact fracture healing in a mouse-osteotomy-model although used routinely in research and clinical application.
Lang, A., Kirchner, M., Stefanowski, J., Durst, M., Weber, M.C., Pfeiffenberger, M., Damerau, A., Hauser, A.E., Hoff, P., Duda, G.N., Buttgereit, F., Schmidt-Bleek, K. and Gaber, T.
Acta Biomaterialia 86
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1 March 2019
Direct zinc finger protein persulfidation by H(2)S is facilitated by Zn(2+).
Lange, M., Ok, K., Shimberg, G.D., Bursac, B., Markó, L., Ivanović-Burmazović, I., Michel, S. and Filipovic, M.R.
Angewandte Chemie International Edition 58
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11 June 2019
Cardiovascular programming during and after diabetic pregnancy: role of placental dysfunction and IUGR.
Langmia, I.M., Kräker, K., Weiss, S.E., Haase, N., Schütte, T., Herse, F. and Dechend, R.
Frontiers in Endocrinology 10
: 215.
April 2019
Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking.
Lareau, C.A., Ludwig, L.S. and Sankaran, V.G.
Blood Advances 3
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23 December 2019
Social networks and protest participation: evidence from 130 million Twitter users.
Larson, J.M., Nagler, J., Ronen, J. and Tucker, J.A.
American Journal of Political Science 63
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July 2019
Allergy and atopy from infancy to adulthood: messages from the German birth cohort MAS.
Lau, S., Matricardi, P.M., Wahn, U., Lee, Y.A. and Keil, T.
Annals of Allergy, Asthma & Immunology 122
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January 2019
Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells.
Le, T.T.H., Tran, N.T., Dao, T.M.L., Nguyen, D.D., Do, H.D., Ha, T.L., Kühn, R., Nguyen, T.L., Rajewsky, K. and Chu, V.T.
Frontiers in Genetics 10
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July 2019
Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma.
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Gut 68
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Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.
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The dynamic nature of senescence in cancer.
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FLAM-seq: full-length mRNA sequencing reveals principles of poly(A) tail length control.
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Nature Methods 16
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Schwere Azidose: Differenzialdiagnostik und Therapie [Severe acidosis: differential diagnostics and treatment].
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November 2019
Subtomogram averaging from cryo-electron tomograms.
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The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G.
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FEBS Letters 593
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March 2019
Intestinal-cell kinase and juvenile myoclonic epilepsy.
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New England Journal of Medicine 380
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18 April 2019
Using SMOG 2 to simulate complex biomolecular assemblies.
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2019
Studying ribosome dynamics with simplified models.
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1 June 2019
Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial.
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Lancet Neurology 18
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August 2019
The Tug1 locus is essential for male fertility.
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bioRxiv
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28 February 2019
Pathophysiological role of caveolae in hypertension.
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Frontiers in Medicine 6
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July 2019
Mapping the MHC class I spliced immunopeptidome of cancer cells.
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Cancer Immunology Research 7
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January 2019
Deubiquitinase USP10 regulates Notch signaling in the endothelium.
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Science 364
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12 April 2019
Angiotensin II type 2 receptor mediates high fat diet-induced cardiomyocyte hypertrophy and hypercholesterolemia.
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1 December 2019
Unknown mutations and genotype/phenotype correlations of autosomal recessive congenital ichthyosis in patients from Saudi Arabia and Pakistan.
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Molecular Genetics & Genomic Medicine 7
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March 2019
Calcyphosine-like (CAPSL) is regulated in multiple symmetric lipomatosis and is involved in adipogenesis.
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Scientific Reports 9
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11 June 2019
Clinical relevance of circulating MACC1 and S100A4 transcripts for ovarian cancer.
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Molecular Oncology 13
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May 2019
Endothelial B2-receptor overexpression as an alternative animal model for hereditary angioedema.
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Sex-specific metabolic and functional differences in human umbilical vein endothelial cells from twin pairs.
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Corrections of myocardial tissue sodium concentration measurements in human cardiac (23)Na MRI at 7 Tesla.
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Magnetic Resonance in Medicine 82
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July 2019
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Scientific American 320
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January 2019
Transcriptional states and chromatin accessibility underlying human erythropoiesis.
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Cell Reports 27
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11 June 2019
Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics.
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7 March 2019
Genome-wide analysis of RNA and protein localization and local translation in mESC-derived neurons.
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Men, mice, and blood pressure: telemetry?
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July 2019
Combined analysis of metabolomes, proteomes, and transcriptomes of hepatitis C virus-infected cells and liver to identify pathways associated with disease development.
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Gastroenterology 157
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August 2019
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16 May 2019
Microtubule cytoskeleton regulates connexin 43 localization and cardiac conduction in cardiomyopathy caused by mutation in A-type lamins gene.
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15 December 2019
Genomic inversions and GOLGA core duplicons underlie disease instability at the 15q25 locus.
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PLoS Genetics 15
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27 March 2019
Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses.
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Scientific Reports 9
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23 December 2019
The role of 17β-estradiol and estrogen receptors in regulation of Ca(2+) channels and mitochondrial function in cardiomyocytes.
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Frontiers in Endocrinology 10
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May 2019
An integrated understanding of the molecular mechanisms how adipose tissue metabolism affects long-term body weight maintenance.
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1 January 2019
Structure-based screening of tetrazolylhydrazide inhibitors versus KDM4 histone demethylases.
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ChemMedChem 14
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6 November 2019
SorCS2 controls functional expression of amino acid transporter EAAT3 and protects neurons from oxidative stress and epilepsy-induced pathology.
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5 March 2019
Excitatory amino acid transporters in physiology and disorders of the central nervous system.
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12 November 2019
Impact of stable angina on health status and quality of life perception of currently treated patients. The BRIDGE 2 survey.
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European Journal of Internal Medicine 70
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November 2019
The discovery of a LEMD2-associated nuclear envelopathy with early progeroid appearance suggests advanced applications for AI-driven facial phenotyping.
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American Journal of Human Genetics 104
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4 April 2019
A new highly thyrotropin receptor-selective small molecule antagonist with potential for the treatment of Graves' orbitopathy.
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Thyroid 29
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23 January 2019
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.
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Nature Communications 10
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18 December 2019
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Nature Methods 16
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September 2019
Evolution of replication origins in vertebrate genomes: rapid turnover despite selective constraints.
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Nucleic Acids Research 47
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4 June 2019
Targeting APLN/APLNR improves antiangiogenic efficiency and blunts proinvasive side effects of VEGFA/VEGFR2 blockade in glioblastoma.
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Cancer Research 79
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May 2019
eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization.
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10 October 2019
Targeted manipulation of brain serotonin: RNAi-mediated knockdown of tryptophan hydroxylase 2 in rats.
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ACS Chemical Neuroscience 10
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17 July 2019
A gene expression atlas of embryonic neurogenesis in Drosophila reveals complex spatiotemporal regulation of lncRNAs.
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28 March 2019
Long-term disability in neuromyelitis optica spectrum disorder with a history of myelitis is associated with age at onset, delay in diagnosis/preventive treatment, MRI lesion length and presence of symptomatic brain lesions.
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Multiple Sclerosis and Related Disorders 28
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February 2019
Transcriptional dynamics of microRNAs and their targets during Drosophila neurogenesis.
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RNA Biology 16
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20 January 2019
BIQ: A method for searching circular RNAs in transcriptome databases by indexing backsplice junctions.
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bioRxiv
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25 February 2019
Targeted genomic integration of EGFP under tubulin beta 3 class III promoter and mEos2 under tryptophan hydroxylase 2 promoter does not produce sufficient levels of reporter gene expression.
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Journal of Cellular Biochemistry 120
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October 2019
High-throughput screening for modulators of CFTR activity based on genetically engineered cystic fibrosis disease-specific iPSCs.
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Stem Cell Reports 12
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11 June 2019
Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.
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Nature 566
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7 February 2019
Little Old Ladies' Eye.
Middeke, M., Nasemann, J. and Luft, F.C.
Artery Research
June 2019
Microbial abundance, activity and population genomic profiling with mOTUs2.
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Nature Communications 10
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4 March 2019
Mapping the lung.
Mildner, A. and Yona, S.
Science 363
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15 March 2019
Nomenclature for cellular plasticity: are the terms as plastic as the cells themselves?
Mills, J.C., Stanger, B.Z. and Sander, M.
EMBO Journal 38
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1 October 2019
Application of europium-doped very small iron oxide nanoparticles to visualize neuroinflammation with MRI and fluorescence microscopy.
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1 April 2019
Assessment of disease progression in dysferlinopathy: a 1-year cohort study.
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29 January 2019
Autosomal-recessive mutations in MESD cause osteogenesis imperfecta.
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American Journal of Human Genetics 105
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3 October 2019
240th ENMC workshop: The involvement of skeletal muscle stem cells in the pathology of muscular dystrophies 25–27 January 2019, Hoofddorp, The Netherlands.
Morgan, J., Butler-Browne, G., Muntoni, F. and Patel, K.
Neuromuscular Disorders 29
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2019
Insights into pancreatic β cell energy metabolism using rodent β cell models.
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Wellcome Open Research 2
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25 September 2019
Characterization of mouse adult testicular macrophage populations by immunofluorescence imaging and flow cytometry.
Mossadegh-Keller, N. and Sieweke, M.H.
Bio-protocol 9
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5 March 2019
A (3D-nuclear) space odyssey: making sense of Hi-C maps.
Mota-Gómez, I. and Lupiáñez, D.G.
Genes 10
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29 May 2019
Normative data and minimally detectable change for inner retinal layer thicknesses using a semi-automated OCT image segmentation pipeline.
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Frontiers in Neurology 10
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November 2019
Proteomic and transcriptomic changes in hibernating grizzly bears reveal metabolic and signaling pathways that protect against muscle atrophy.
Mugahid, D.A., Sengul, T.G., You, X., Wang, Y., Steil, L., Bergmann, N., Radke, M.H., Ofenbauer, A., Gesell-Salazar, M., Balogh, A., Kempa, S., Tursun, B., Robbins, C.T., Völker, U., Chen, W., Nelson, L. and Gotthardt, M.
Scientific Reports 9
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27 December 2019
Deciphering human ribonucleoprotein regulatory networks.
Mukherjee, N., Wessels, H.H., Lebedeva, S., Sajek, M., Ghanbari, M., Garzia, A., Munteanu, A., Yusuf, D., Farazi, T., Hoell, J.I., Akat, K.M., Akalin, A., Tuschl, T. and Ohler, U.
Nucleic Acids Research 47
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25 January 2019
Mutations in PIGB cause an inherited GPI biosynthesis defect with an axonal neuropathy and metabolic abnormality in severe cases.
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IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia.
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Chronic CD30-signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells.
Sperling, S.A., Fiedler, P., Lechner, M., Pollithy, A., Ehrenberg, S., Schiefer, A.I., Kenner, L., Feuchtinger, A., Kühn, R., Swinerd, G., Schmidt-Supprian, M., Strobl, L.J. and Zimber-Strobl, U.
Blood 133
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13 June 2019
Associations of current, childhood, and adolescent milk intake with serum insulin-like growth factor (IGF)-1 and IGF binding protein 3 concentrations in adulthood.
Srinivasan, V., Nimptsch, K. and Rohrmann, S.
Nutrition and Cancer 71
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2019
Imaging glioma progression by intravital microscopy.
Stanchi, F., Matsumoto, K. and Gerhardt, H.
Methods in Molecular Biology 1862
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2019
Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Starossom, S.C., Campo Garcia, J., Woelfle, T., Romero-Suarez, S., Olah, M., Watanabe, F., Cao, L., Yeste, A., Tukker, J.J., Quintana, F.J., Imitola, J., Witzel, F., Schmitz, D., Morkel, M., Paul, F., Infante-Duarte, C. and Khoury, S.J.
Nature Communications 10
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15 January 2019
Does time equal vision in the acute treatment of a cohort of AQP4 and MOG optic neuritis?
Stiebel-Kalish, H., Hellmann, M.A., Mimouni, M., Paul, F., Bialer, O., Bach, M. and Lotan, I.
Neurology Neuroimmunology & Neuroinflammation 6
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July 2019
Scalable workflows and reproducible data analysis for genomics.
Strozzi, F., Janssen, R., Wurmus, R., Crusoe, M.R., Githinji, G., Di Tommaso, P., Belhachemi, D., Möller, S., Smant, G., de Ligt, J. and Prins, P.
Methods in Molecular Biology 1910
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2019
Cardiac magnetic resonance imaging at 7 Tesla.
Stäb, D., Al Najjar, A., O'Brien, K., Strugnell, W., Richer, J., Rieger, J., Niendorf, T. and Barth, M.
Journal of Visualized Experiments
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6 January 2019
Human-specific tandem repeat expansion and differential gene expression during primate evolution.
Sulovari, A., Li, R., Audano, P.A., Porubsky, D., Vollger, M.R., Logsdon, G.A., Warren, W.C., Pollen, A.A., Chaisson, M.J.P. and Eichler, E.E.
Proceedings of the National Academy of Sciences of the United States of America 116
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12 November 2019
A semisynthetic peptide-metalloporphyrin responsive matrix for artificial photosynthesis.
Sun, Z., Diebolder, C.A., Renault, L. and de Groot, H.
ChemPhotoChem 3
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August 2019
53BP1 supports immunoglobulin class switch recombination independently of its DNA double-strand break end protection function.
Sundaravinayagam, D., Rahjouei, A., Andreani, M., Tupiņa, D., Balasubramanian, S., Saha, T., Delgado-Benito, V., Coralluzzo, V., Daumke, O. and Di Virgilio, M.
Cell Reports 28
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6 August 2019
A convex relaxation for multi-graph matching.
Swoboda, P., Kainmüller, D., Mokarian, A., Theobalt, C. and Bernard, F.
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STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets.
Szklarczyk, D., Gable, A.L., Lyon, D., Junge, A., Wyder, S., Huerta-Cepas, J., Simonovic, M., Doncheva, N.T., Morris, J.H., Bork, P., Jensen, L.J. and von Mering, C.
Nucleic Acids Research 47
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8 January 2019
Fast cross correlation for limited angle tomographic data.
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Postprandial duration influences the association of insulin-related dietary indexes and plasma C-peptide concentrations in adult men and women.
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Journal of Nutrition 149
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1 February 2019
Urinary renin in patients and mice with diabetic kidney disease.
Tang, J., Wysocki, J., Ye, M., Vallés, P.G., Rein, J., Shirazi, M., Bader, M., Gomez, R.A., Sequeira-Lopez, M.L.S., Afkarian, M. and Batlle, D.
Hypertension 74
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July 2019
Venetoclax resistance and acquired mutations in chronic lymphocytic leukemia.
Tausch, E., Close, W., Dolnik, A., Bloehdorn, J., Chyla, B., Bullinger, L., Döhner, H., Mertens, D. and Stilgenbauer, S.
Haematologica 104
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September 2019
The Pediatric Cell Atlas: defining the growth phase of human development at single-cell resolution.
Taylor, D.M., Aronow, B.J., Tan, K., Bernt, K., Salomonis, N., Greene, C.S., Frolova, A., Henrickson, S.E., Wells, A., Pei, L., Jaiswal, J.K., Whitsett, J., Hamilton, K.E., MacParland, S.A., Kelsen, J., Heuckeroth, R.O., Potter, S.S., Vella, L.A., Terry, N.A., Ghanem, L.R., Kennedy, B.C., Helbig, I., Sullivan, K.E., Castelo-Soccio, L., Kreigstein, A., Herse, F., Nawijn, M.C., Koppelman, G.H., Haendel, M., Harris, N.L., Rokita, J.L., Zhang, Y., Regev, A., Rozenblatt-Rosen, O., Rood, J.E., Tickle, T.L, Vento-Tormo, R., Alimohamed, S., Lek, M., Mar, J.C., Loomes, K.M., Barrett, D.M., Uapinyoying, P., Beggs, A.H., Agrawal, P.B., Chen, Y.W., Muir, A.B., Garmire, L.X., Snapper, S.B., Nazarian, J., Seeholzer, S.H., Fazelinia, H., Singh, L.N., Faryabi, R.B., Raman, P., Dawany, N., Xie, H.M., Devkota, B., Diskin, S.J., Anderson, S.A., Rappaport, E.F., Peranteau, W., Wikenheiser-Brokamp, K.A., Teichmann, S., Wallace, D., Peng, T., Ding, Y.Y., Kim, M.S., Xing, Y., Kong, S.W., Bönnemann, C.G., Mandl, K.D. and White, P.S.
Developmental Cell 49
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8 April 2019
A transcriptome-wide analysis deciphers distinct roles of G1 cyclins in temporal organization of the yeast cell cycle.
Teufel, L., Tummler, K., Flöttmann, M., Herrmann, A., Barkai, N. and Klipp, E.
Scientific Reports 9
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4 March 2019
Identification of proteins and miRNAs that specifically bind an mRNA in vivo.
Theil, K., Imami, K. and Rajewsky, N.
Nature Communications 10
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16 September 2019
The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2: a phosphatidylserine flippase.
Theorin, L., Faxén, K., Sørensen, D.M., Migotti, R., Dittmar, G., Schiller, J., Daleke, D.L., Palmgren, M., López-Marqués, R.L. and Pomorski, T.G.
Biochemical Journal 476
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6 March 2019
Critical parameters for the controlled synthesis of nanogels suitable for temperature-triggered protein delivery.
Theune, L.E., Charbaji, R., Kar, M., Wedepohl, S., Hedtrich, S. and Calderón, M.
Materials Science and Engineering C: Materials for Biological Applications 100
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July 2019
Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation.
Thomas, A.M., Manghi, P., Asnicar, F., Pasolli, E., Armanini, F., Zolfo, M., Beghini, F., Manara, S., Karcher, N., Pozzi, C., Gandini, S., Serrano, D., Tarallo, S., Francavilla, A., Gallo, G., Trompetto, M., Ferrero, G., Mizutani, S., Shiroma, H., Shiba, S., Shibata, T., Yachida, S., Yamada, T., Wirbel, J., Schrotz-King, P., Ulrich, C.M., Brenner, H., Arumugam, M., Bork, P., Zeller, G., Cordero, F., Dias-Neto, E., Setubal, J.C., Tett, A., Pardini, B., Rescigno, M., Waldron, L., Naccarati, A. and Segata, N.
Nature Medicine 25
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April 2019
Patients with hypokalemia develop WNK bodies in the distal convoluted tubule of the kidney.
Thomson, M.N., Schneider, W., Mutig, K., Ellison, D.H., Kettritz, R. and Bachmann, S.
American Journal of Physiology Renal Physiology 316
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February 2019
Population-level analysis of Blastocystis subtype prevalence and variation in the human gut microbiota.
Tito, R.Y., Chaffron, S., Caenepeel, C., Lima-Mendez, G., Wang, J., Vieira-Silva, S., Falony, G., Hildebrand, F., Darzi, Y., Rymenans, L., Verspecht, C., Bork, P., Vermeire, S., Joossens, M. and Raes, J.
Gut 68
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7 June 2019
SarcTrack: an adaptable software tool for efficient large-scale analysis of sarcomere function in hiPSC-cardiomyocytes.
Toepfer, C.N., Sharma, A., Cicconet, M., Garfinkel, A.C., Mücke, M., Neyazi, M., Willcox, J.A.L., Agarwal, R., Schmid, M., Rao, J., Ewoldt, J., Pourquié, O., Chopra, A., Chen, C.S., Seidman, J.G. and Seidman, C.E.
Circulation Research 124
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12 April 2019
Female sex is protective in a preclinical model of heart failure with preserved ejection fraction.
Tong, D., Schiattarella, G.G., Jiang, N., May, H.I., Lavandero, S., Gillette, T.G. and Hill, J.A.
Circulation 140
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19 November 2019
Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors.
Tran, N.T., Bashir, S., Li, X., Rossius, J., Chu, V.T., Rajewsky, K. and Kühn, R.
Frontiers in Genetics 10
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30 April 2019
Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells.
Tran, N.T., Sommermann, T., Graf, R., Trombke, J., Pempe, J., Petsch, K., Kühn, R., Rajewsky, K. and Chu, V.T.
Cell Reports 28
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24 September 2019
Anti-β1-adrenoreceptor auto-antibodies in elderly heart failure patients.
Trippel, T.D., Mueller, D.N., Obradovic, D., Edelmann, F., Tahirovic, E., Wilck, N., Riemekasten, G., Dragun, D., Busjahn, A., Heidecke, H., Junker, J., Pieske, B., Dungen, H.D. and Dechend, R.
Frontiers in Bioscience 24
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1 March 2019
Distinguishing between biological and technical replicates in hypertension research on isolated arteries.
Tsvetkov, D., Kolpakov, E., Kassmann, M., Schubert, R. and Gollasch, M.
Frontiers in Medicine 6
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June 2019
How RB1CC1/FIP200 claws its way to autophagic engulfment of SQSTM1/p62-ubiquitin condensates.
Turco, E., Witt, M., Abert, C., Bock-Bierbaum, T., Su, M.Y., Trapannone, R., Sztacho, M., Danieli, A., Shi, X., Zaffagnini, G., Gamper, A., Schuschnig, M., Fracchiolla, D., Bernklau, D., Romanov, J., Hartl, M., Hurley, J.H., Daumke, O. and Martens, S.
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FIP200 claw domain binding to p62 promotes autophagosome formation at ubiquitin condensates.
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Molecular Cell 74
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18 April 2019
Remodeling of substrate consumption in the murine sTAC model of heart failure.
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Interrogation of human hematopoiesis at single-cell and single-variant resolution.
Ulirsch, J.C., Lareau, C.A., Bao, E.L., Ludwig, L.S., Guo, M.H., Benner, C., Satpathy, A.T., Kartha, V.K., Salem, R.M., Hirschhorn, J.N., Finucane, H.K., Aryee, M.J., Buenrostro, J.D. and Sankaran, V.G.
Nature Genetics 51
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April 2019
Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels.
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eLife 8
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Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
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Nature Communications 10
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1 March 2019
Conserved pseudoknots in lncRNA MEG3 are essential for stimulation of the p53 pathway.
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5 September 2019
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Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain.
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Proteogenomic analysis of human colon cancer reveals new therapeutic opportunities.
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Contactless recording of sleep apnea and periodic leg movements by nocturnal 3-D-video and subsequent visual perceptive computing.
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Scientific Reports 9
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14 November 2019
Association of a PD-L2 gene polymorphism with chronic lymphatic filariasis in a South Indian cohort.
Venugopal, G., O'Regan, N.L., Babu, S., Schumann, R.R., Srikantam, A., Merle, R., Hartmann, S. and Steinfelder, S.
American Journal of Tropical Medicine and Hygiene 100
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February 2019
Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart.
Vidal, R., Wagner, J.U.G., Braeuning, C., Fischer, C., Patrick, R., Tombor, L., Muhly-Reinholz, M., John, D., Kliem, M., Conrad, T., Guimarães-Camboa, N., Harvey, R., Dimmeler, S. and Sauer, S.
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14 November 2019
Canonical BMP signaling in tubular cells mediates recovery after acute kidney injury.
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Fibroblast primary cilia are required for cardiac fibrosis.
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14 May 2019
Applying synergy metrics to oncology combination screening data: agreements, disagreements and pitfalls.
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December 2019
Human sFLT1 leads to severe changes in placental differentiation and vascularization in a transgenic hsFLT1/rtTA FGR mouse model.
Vogtmann, R., Kühnel, E., Dicke, N., Verkaik-Schakel, R.N., Plösch, T., Schorle, H., Stojanovska, V., Herse, F., Köninger, A., Kimmig, R., Winterhager, E. and Gellhaus, A.
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Fluconazole increases osmotic water transport in renal collecting duct through effects on aquaporin-2 trafficking.
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Journal of the American Society of Nephrology 30
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The translational landscape of the human heart.
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Lack of brain serotonin affects feeding and differentiation of newborn cells in the adult hypothalamus.
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Frontiers in Cell and Developmental Biology 7
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Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V., McShane, E., Schulz-Beiss, K.W., Patone, G., Schleussner, N., Kolesnichenko, M., Hübner, N., Daumke, O., Selbach, M., Akalin, A., Mathas, S. and Scheidereit, C.
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Empfehlungen zu kardialen MRT-Untersuchungen bei Patienten mit Herzschrittmachern und implantierbaren Kardioverter-Defibrillatoren [Recommendations for cardiac magnetic resonance imaging in patients with cardiac pacemakers andimplantable cardioverter defibrillators].
von Knobelsdorff-Brenkenhoff, F., Bauer, W.R., Deneke, T., Fleck, E., Rolf, A., Schulz-Menger, J., Sommer, P., Tillmanns, C. and Eitel, I.
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The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma.
Wagener, R., Seufert, J., Raimondi, F., Bens, S., Kleinheinz, K., Nagel, I., Altmüller, J., Thiele, H., Hübschmann, D., Kohler, C.W., Nürnberg, P., Au-Yeung, R., Burkhardt, B., Horn, H., Leoncini, L., Jaffe, E.S., Ott, G., Rymkiewicz, G., Schlesner, M., Russell, R.B., Klapper, W. and Siebert, R.
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Efficacy of high-frequency repetitive transcranial magnetic stimulation in schizophrenia patients with treatment-resistant negative symptoms treated with clozapine.
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Fluorine-19 MRI at 21.1 T: enhanced spin-lattice relaxation of perfluoro-15-crown-5-ether and sensitivity as demonstrated in ex vivo murine neuroinflammation.
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February 2019
Special issue on fluorine-19 magnetic resonance: technical solutions, research promises and frontier applications.
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Magnetic Resonance Materials in Physics Biology and Medicine 32
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Serotonin deficiency increases context-dependent fear learning through modulation of hippocampal activity.
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De novo mutations in FOXJ1 result in a motile ciliopathy with hydrocephalus and randomization of left/right body asymmetry.
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American Journal of Human Genetics 105
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7 November 2019
In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia.
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Journal of Clinical Investigation 129
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1 February 2019
Long and repeat-rich intronic sequences favor circular RNA formation under conditions of reduced spliceosome activity.
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Increased retention of gadolinium in the inflamed brain after repeated administration of gadopentetate dimeglumine: a proof-of-concept study in mice combining ICP-MS and micro- and nano-SR-XRF.
Wang, S., Hesse, B., Roman, M., Stier, D., Castillo-Michel, H., Cotte, M., Suuronen, J.P., Lagrange, A., Radbruch, H., Paul, F., Taupitz, M., Schellenberger, E., Sack, I. and Infante-Duarte, C.
Investigative Radiology 54
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October 2019
Full-length transcriptome reconstruction reveals a large diversity of RNA and protein isoforms in rat hippocampus.
Wang, X., You, X., Langer, J.D., Hou, J., Rupprecht, F., Vlatkovic, I., Quedenau, C., Tushev, G., Epstein, I., Schaefke, B., Sun, W., Fang, L., Li, G., Hu, Y., Schuman, E.M. and Chen, W.
Nature Communications 10
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1 November 2019
The pathobiology of perturbed mutant huntingtin protein-protein interactions in Huntington's disease.
Wanker, E.E., Ast, A., Schindler, F., Trepte, P. and Schnoegl, S.
Journal of Neurochemistry 151
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November 2019
The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats.
Warrington, J.P., Fan, F., Duncan, J., Cunningham, M.W., LaMarca, B.B., Dechend, R., Wallukat, G., Roman, R.J., Drummond, H.A., Granger, J.P. and Ryan, M.J.
Biology of Sex Differences 10
(1): 58.
11 December 2019
A novel allele for inducible Cre expression in germinal center B cells.
Weber, T., Seagal, J., Winkler, W., Wirtz, T., Chu, V.T. and Rajewsky, K.
European Journal of Immunology 49
(1): 192-194.
January 2019
Germline loss-of-function variants in the BARD1 gene are associated with early-onset familial breast cancer but not ovarian cancer.
Weber-Lassalle, N., Borde, J., Weber-Lassalle, K., Horváth, J., Niederacher, D., Arnold, N., Kaulfuß, S., Ernst, C., Paul, V.G., Honisch, E., Klaschik, K., Volk, A.E., Kubisch, C., Rapp, S., Lichey, N., Altmüller, J., Lepkes, L., Pohl-Rescigno, E., Thiele, H., Nürnberg, P., Larsen, M., Richters, L., Rhiem, K., Wappenschmidt, B., Engel, C., Meindl, A., Schmutzler, R.K., Hahnen, E. and Hauke, J.
Breast Cancer Research 21
(1): 55.
29 April 2019
Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.
Wei, W., Hennig, B.P., Wang, J., Zhang, Y., Piazza, I., Pareja Sanchez, Y., Chabbert, C.D., Adjalley, S.H., Steinmetz, L.M. and Pelechano, V.
Genome Research 29
(12): 1974-1984.
December 2019
Spatially restricted stromal Wnt signaling restrains prostate epithelial progenitor growth through direct and indirect mechanisms.
Wei, X., Zhang, L., Zhou, Z., Kwon, O.J., Zhang, Y., Nguyen, H., Dumpit, R., True, L., Nelson, P., Dong, B., Xue, W., Birchmeier, W., Taketo, M.M., Xu, F., Creighton, C.J., Ittmann, M.M. and Xin, L.
Cell Stem Cell 24
(5): 753-768.
2 May 2019
Splicing factor Rbm10 facilitates heterochromatin assembly in fission yeast.
Weigt, M., Gao, Q., Ban, H., He, H., Mastrobuoni, G., Kempa, S., Chen, W. and Li, F.
bioRxiv
: 518936.
11 January 2019
Functional LGE imaging: cardiac phase-resolved assessment of focal fibrosis.
Weingartner, S., Demirel, O.B., Shenoy, C., Schad, L.R., Schulz-Menger, J. and Akcakaya, M.
In: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 23-27 Jul 2019, Berlin, Germany.
2019
3D organ models-Revolution in pharmacological research?
Weinhart, M., Hocke, A., Hippenstiel, S., Kurreck, J. and Hedtrich, S.
Pharmacological Research 139
: 446-451.
January 2019
Health-related quality of life and neurocognitive functioning with lomustine-temozolomide versus temozolomide in patients with newly diagnosed, MGMT-methylated glioblastoma (CeTeG/NOA-09): a randomised, multicentre, open-label, phase 3 trial.
Weller, J., Tzaridis, T., Mack, F., Steinbach, J.P., Schlegel, U., Hau, P., Krex, D., Grauer, O., Goldbrunner, R., Bähr, O., Uhl, M., Seidel, C., Tabatabai, G., Brehmer, S., Bullinger, L., Galldiks, N., Schaub, C., Kebir, S., Stummer, W., Simon, M., Fimmers, R., Coch, C., Glas, M., Herrlinger, U. and Schäfer, N.
Lancet Oncology 20
(10): 1444-1453.
October 2019
Global identification of functional microRNA-mRNA interactions in Drosophila.
Wessels, H.H., Lebedeva, S., Hirsekorn, A., Wurmus, R., Akalin, A., Mukherjee, N. and Ohler, U.
Nature Communications 10
(1): 1626.
9 April 2019
Distinct genetic alterations and luminal molecular subtype in nested variant of urothelial carcinoma (NVUC).
Weyerer, V., Weisser, R., Moskalev, E.A., Haller, F., Stoehr, R., Eckstein, M., Zinnall, U., Gaisa, N.T., Compérat, E., Perren, A., Keck, B., Allory, Y., Kristiansen, G., Wullich, B., Agaimy, A., Hartmann, A. and Bertz, S.
Histopathology 75
(6): 865-875.
December 2019
Neural mechanisms of perceptual decision-making and their link to neuropsychiatric symptoms in multiple sclerosis.
Weygandt, M., Behrens, J., Brasanac, J., Söder, E., Meyer-Arndt, L., Wakonig, K., Ritter, K., Brandt, A.U., Bellmann-Strobl, J., Gold, S.M., Haynes, J.D. and Paul, F.
Multiple Sclerosis and Related Disorders 33
: 139-145.
August 2019
Interactions between neural decision-making circuits predict long-term dietary treatment success in obesity.
Weygandt, M., Spranger, J., Leupelt, V., Maurer, L., Bobbert, T., Mai, K. and Haynes, J.D.
NeuroImage 184
: 520-534.
1 January 2019
The role of sodium in modulating immune cell function.
Wilck, N., Balogh, A., Markó, L., Bartolomaeus, H. and Müller, D.N.
Nature Reviews Nephrology 15
(9): 546-558.
September 2019
Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis.
Wild, P., Susperregui, A., Piazza, I., Dörig, C., Oke, A., Arter, M., Yamaguchi, M., Hilditch, A.T., Vuina, K., Chan, K.C., Gromova, T., Haber, J.E., Fung, J.C., Picotti, P. and Matos, J.
Molecular Cell 75
(4): 859-874.
22 August 2019
High salt inhibits tumor growth by enhancing anti-tumor immunity.
Willebrand, R., Hamad, I., Van Zeebroeck, L., Kiss, M., Bruderek, K., Geuzens, A., Swinnen, D., Côrte-Real, B.F., Markó, L., Lebegge, E., Laoui, D., Kemna, J., Kammertoens, T., Brandau, S., Van Ginderachter, J.A. and Kleinewietfeld, M.
Frontiers in Immunology 10
: 1141.
4 June 2019
4D flow imaging with 2D-selective excitation.
Wink, C., Ferrazzi, G., Bassenge, J.P., Flassbeck, S., Schmidt, S., Schaeffter, T. and Schmitter, S.
Magnetic Resonance in Medicine 82
(3): 886-900.
September 2019
Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer.
Wirbel, J., Pyl, P.T., Kartal, E., Zych, K., Kashani, A., Milanese, A., Fleck, J.S., Voigt, A.Y., Palleja, A., Ponnudurai, R., Sunagawa, S., Coelho, L.P., Schrotz-King, P., Vogtmann, E., Habermann, N., Niméus, E., Thomas, A.M., Manghi, P., Gandini, S., Serrano, D., Mizutani, S., Shiroma, H., Shiba, S., Shibata, T., Yachida, S., Yamada, T., Waldron, L., Naccarati, A., Segata, N., Sinha, R., Ulrich, C.M., Brenner, H., Arumugam, M., Bork, P. and Zeller, G.
Nature Medicine 25
(4): 679-689.
April 2019
Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)-study protocol for a randomized controlled trial.
Wirth, M., Schwarz, C., Benson, G., Horn, N., Buchert, R., Lange, C., Köbe, T., Hetzer, S., Maglione, M., Michael, E., Märschenz, S., Mai, K., Kopp, U., Schmitz, D., Grittner, U., Sigrist, S.J., Stekovic, S., Madeo, F. and Flöel, A.
Alzheimer's Research & Therapy 11
(1): 36.
1 May 2019
Insulin-like growth factor binding protein 2 (IGFBP-2) and the risk of developing type 2 diabetes.
Wittenbecher, C., Ouni, M., Kuxhaus, O., Jähnert, M., Gottmann, P., Teichmann, A., Meidtner, K., Kriebel, J., Grallert, H., Pischon, T., Boeing, H., Schulze, M.B. and Schürmann, A.
Diabetes 68
(1): 188-197.
1 January 2019
Retroperitoneal hematoma after bone marrow biopsy: the first cut should not be the deepest.
Wojciechowski, A., Duckert, M., Hartmann, J., Bullinger, L. and Matzdorff, A.
Oncology Research and Treatment 42
(5): 283-288.
May 2019
PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells.
Wolf, F.A., Hamey, F.K., Plass, M., Solana, J., Dahlin, J.S., Göttgens, B., Rajewsky, N., Simon, L. and Theis, F.J.
Genome Biology 20
(1): 59.
19 March 2019
CRISPR-activation-based screen reveals neuronal fate promotion by polycomb repressive complex 2 during direct reprogramming.
Wolfram, T. and Tursun, B.
Stem Cell Investigation 6
: 32.
September 2019
Muscle wasting and function after muscle activation and early protocol-based physiotherapy: an explorative trial.
Wollersheim, T., Grunow, J.J., Carbon, N.M., Haas, K., Malleike, J., Ramme, S.F., Schneider, J., Spies, C.D., Märdian, S., Mai, K., Spuler, S., Fielitz, J. and Weber-Carstens, S.
Journal of Cachexia Sarcopenia and Muscle 10
(4): 734-747.
August 2019
B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.
Wong, J.B., Hewitt, S.L., Heltemes-Harris, L.M., Mandal, M., Johnson, K., Rajewsky, K., Koralov, S.B., Clark, M.R., Farrar, M.A. and Skok, J.A.
Nature Communications 10
(1): 4768.
18 October 2019
The cell adhesion protein CAR is a negative regulator of synaptic transmission.
Wrackmeyer, U., Kaldrack, J., Jüttner, R., Pannasch, U., Gimber, N., Freiberg, F., Purfürst, B., Kainmueller, D., Schmitz, D., Haucke, V., Rathjen, F.G. and Gotthardt, M.
Scientific Reports 9
(1): 6768.
1 May 2019
HOT or not: examining the basis of high-occupancy target regions.
Wreczycka, K., Franke, V., Uyar, B., Wurmus, R., Bulut, S., Tursun, B. and Akalin, A.
Nucleic Acids Research
: gkz460.
20 June 2019
Clinical relevance of semaphorin-3F in patients with prostate cancer.
Wu, G.
Clinical and Investigative Medicine 42
(3): E64-E69.
29 September 2019
Dosis und Wirkung in der Toxikologie: die Haber'sche Regel und Ableitungen.
Wunderlich, V.
BIOspektrum 25
(5): 584-585.
September 2019
Die Kenntnis der Krebskrankheit aus historischer Perspektive: Das beispiellose Werk des Berliner Arztes Jacob Wolff (1861–1938).
Wunderlich, V.
Acta Historica Leopoldina 74
: 221-247.
2019
Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program.
Wyler, E., Franke, V., Menegatti, J., Kocks, C., Boltengagen, A., Praktiknjo, S., Walch-Rückheim, B., Bosse, J., Rajewsky, N., Grässer, F., Akalin, A. and Landthaler, M.
Nature Communications 10
(1): 4878.
25 October 2019
Y
Systemic outcomes of (Pyr(1))-apelin-13 infusion at mid-late pregnancy in a rat model with preeclamptic features.
Yamaleyeva, L.M., Brosnihan, K.B., Elsangeedy, E., McGee, C., Shi, S., Caudell, D., Miller, C., Varagic, J., Bader, M., Dechend, R. and Shaltout, H.A.
Scientific Reports 9
(1): 8579.
12 June 2019
(In situ) conformational changes of the Escherichia coli serine chemoreceptor in different signaling states.
Yang, W., Cassidy, C.K., Ames, P., Diebolder, C.A., Schulten, K., Luthey-Schulten, Z., Parkinson, J.S. and Briegel, A.
mBio 10
(4): e00973.
2 July 2019
Epigenetic co-deregulation of EZH2/TET1 is a senescence-countering, actionable vulnerability in triple-negative breast cancer.
Yu, Y., Qi, J., Xiong, J., Jiang, L., Cui, D., He, J., Chen, P., Li, L., Wu, C., Ma, T., Shao, S., Wang, J., Yu, D., Zhou, B., Huang, D., Schmitt, C.A. and Tao, R.
Theranostics 9
(3): 761-777.
24 January 2019
Efficient gene editing of human induced pluripotent stem cells using CRISPR/Cas9.
Yumlu, S., Bashir, S., Stumm, J. and Kühn, R.
Methods in Molecular Biology 1961
: 137-151.
2019
Z
One-pot synthesis of poly(glycerol-co-succinic acid) nanogels for dermal delivery.
Zabihi, F., Koeppe, H., Achazi, K., Hedtrich, S. and Haag, R.
Biomacromolecules 20
(5): 1867-1875.
13 May 2019
Integrated phosphoproteome and transcriptome analysis reveals Chlamydia-induced epithelial-to-mesenchymal transition in host cells.
Zadora, P.K., Chumduri, C., Imami, K., Berger, H., Mi, Y., Selbach, M., Meyer, T.F. and Gurumurthy, R.K.
Cell Reports 26
(5): 1286-1302.
29 January 2019
Non-invasive metastasis prognosis from plasma metabolites in stage II colorectal cancer patients: the DACHS study.
Zaimenko, I., Jaeger, C., Brenner, H., Chang-Claude, J., Hoffmeister, M., Grötzinger, C., Detjen, K., Burock, S., Schmitt, C.A., Stein, U. and Lisec, J.
International Journal of Cancer 145
(1): 221-231.
1 July 2019
Quantification in cardiovascular magnetic resonance: agreement of software from three different vendors on assessment of left ventricular function, 2D flow and parametric mapping.
Zange, L., Muehlberg, F., Blaszczyk, E., Schwenke, S., Traber, J., Funk, S. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 21
(1): 12.
21 February 2019
Increased ethanol consumption and locomotion develop upon ethanol deprivation in rats overexpressing the adenosine A(2A) receptor.
Zaniewska, M., Gawliński, D., Wyczesana, M., Nowak, E., Kula, K., Maciów-Głąb, M., Jastrzębska, J., Sadakierska-Chudy, A., Bader, M. and Fuxe, K.
Neuroscience 418
: 133-148.
15 October 2019
TMT labeling for the masses: a robust and cost-efficient, in-solution labeling approach.
Zecha, J., Satpathy, S., Kanashova, T., Avanessian, S.C., Kane, M.H., Clauser, K.R., Mertins, P., Carr, S.A. and Kuster, B.
Molecular & Cellular Proteomics 18
(7): 1468-1478.
1 July 2019
Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex.
Zhang, G., Kruse, T., Guasch Boldú, C., Garvanska, D.H., Coscia, F., Mann, M., Barisic, M. and Nilsson, J.
EMBO Journal 38
(7): e100977.
1 April 2019
Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence.
Zhang, H., Alsaleh, G., Feltham, J., Sun, Y., Napolitano, G., Riffelmacher, T., Charles, P., Frau, L., Hublitz, P., Yu, Z., Mohammed, S., Ballabio, A., Balabanov, S., Mellor, J. and Simon, A.K.
Molecular Cell 76
(1): 110-125.
3 October 2019
Rapid synthesis of γ-halide/pseudohalide-substituted cyanine sensors with programmed generation of singlet oxygen.
Zhang, Q., Xu, S., Lai, F., Wang, Y., Zhang, N., Nazare, M. and Hu, H.Y.
Organic Letters 21
(7): 2121-2125.
5 April 2019
Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations.
Zhao, W., Bohleber, S., Schmidt, H., Seeher, S., Howard, M.T., Braun, D., Arndt, S., Reuter, U., Wende, H., Birchmeier, C., Fradejas-Villar, N. and Schweizer, U.
Journal of Biological Chemistry 294
(39): 14185-14200.
27 September 2019
Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1.
Zhao, X., Nedvetsky, P., Stanchi, F., Vion, A.C., Popp, O., Zühlke, K., Dittmar, G., Klussmann, E. and Gerhardt, H.
eLife 8
: e46380.
3 October 2019
Delayed allogeneic skin graft rejection in CD26-deficient mice.
Zhao, X., Zhang, K., Daniel, P., Wisbrun, N., Fuchs, H. and Fan, H.
Cellular and Molecular Immunology 16
(6): 557-567.
June 2019
A novel predictor tool of biochemical recurrence after radical prostatectomy based on a five-microRNA tissue signature.
Zhao, Z., Weickmann, S., Jung, M., Lein, M., Kilic, E., Stephan, C., Erbersdobler, A., Fendler, A. and Jung, K.
Cancers 11
(10): 1603.
21 October 2019
The KCNE2 potassium channel β subunit is required for normal lung function and resilience to ischemia and reperfusion injury.
Zhou, L., Köhncke, C., Hu, Z., Roepke, T.K. and Abbott, G.W.
FASEB Journal 33
(9): 9762-9774.
September 2019
The Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer.
Zhu, Q., Fang, L., Heuberger, J., Kranz, A., Schipper, J., Scheckenbach, K., Oliveira Vidal, R., Sunaga-Franze, D.Y., Müller, M., Wulf-Goldenberg, A., Sauer, S. and Birchmeier, W.
Cell Reports 26
(2): 415-428.
8 January 2019
Hyponatriämie in Notfall- und Intensivmedizin [Hyponatremia in emergency and critical care medicine].
Zickler, D. and Schmidt-Ott, K.M.
Nephrologe 14
(6): 422-430.
November 2019
The importance of developing therapies targeting the biological spectrum of metastatic disease.
Zijlstra, A., Von Lersner, A., Yu, D., Borrello, L., Oudin, M., Kang, Y., Sahai, E., Fingleton, B., Stein, U., Cox, T.R., Price, J.T., Kato, Y., Welm, A.L. and Aguirre-Ghiso, J.A.
Clinical and Experimental Metastasis 36
(4): 305-309.
August 2019
Ç
Intracellular expression of FLT3 in Purkinje cells: implications for adoptive T-cell therapies.
Çakmak-Görür, N., Radke, J., Rhein, S., Schumann, E., Willimsky, G., Heppner, F.L., Blankenstein, T. and Pezzutto, A.
Leukemia 33
(4): 1039-1043.
April 2019
This list was generated on Thu Aug 15 21:11:43 2024 UTC.