Browse by Research Team

2012

Evolutionary molecular medicine.
Nesse, R.M. and Ganten, D. and Gregory, T.R. and Omenn, G.S.
Journal of Molecular Medicine 90 (5): 509-522. May 2012

The evolution of evolutionary molecular medicine : Genomics are transforming evolutionary biology into a science with new importance for modern medicine.
Ganten, D. and Nesse, R.
Journal of Molecular Medicine 90 (5): 467-470. May 2012

2008

Estrogen, nitric oxide, and hypertension differentially modulate agonist-induced contractile responses in female transgenic (mRen2)27 hypertensive rats.
Brosnihan, K.B. and Li, P. and Figueroa, J.P. and Ganten, D. and Ferrario, C.M.
American Journal of Physiology Heart and Circulatory Physiology 294 (5): H1995-H2001. 1 May 2008

2007

Primary role of angiotensin converting enzyme 2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats.
Trask, A.J. and Averill, D.B. and Ganten, D. and Chappell, M.C. and Ferrario, C.M.
American Journal of Physiology Heart and Circulatory Physiology 292 (6): H3019-H3024. 1 June 2007

2006

Rats with low brain angiotensinogen do not exhibit insulin resistance during early aging.
Kasper, S.O. and Ferrario, C.M. and Ganten, D. and Diz, D.I.
Endocrine 30 (2): 167-174. October 2006

Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine.
Ganten, D. and Ruckpaul, K.
Springer, Berlin [u.a.]. ISBN 3-540-44244-8 2006

Molekularmedizinische Grundlagen von para- und autokrinen Regulationsstoerungen.
Ganten, D. and Ruckpaul, K. and Koehrle, J.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-28781-7 2006

2005

Growth, metabolism and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems.
Kasper, S.O. and Carter, C.S. and Ferrario, C.M. and Ganten, D. and Ferder, L.F. and Sonntag, W.E. and Gallagher, P.E. and Diz, D.I.
Physiological Genomics 23 : 311-317. 30 August 2005

Effects of sodium restriction and cyclooxygenase-2 inhibition on the course of hypertension, proteinuria and cardiac hypertrophy in Ren-2 transgenic rats.
Vaneckova, I. and Skaroupkova, P. and Dvorak, P. and Certikova-Chabova, V. and Tesar, V. and Bader, M. and Ganten, D. and Kramer, J.J.
Physiological Research 54 (1): 17-24. 1 January 2005

Identification of hypertension-related genes through an integrated genomic-transcriptomic approach.
Yagil, C. and Huebner, N. and Monti, J. and Schulz, H. and Sapojnikov, M. and Luft, F.C. and Ganten, D. and Yagil, Y.
Circulation Research 96 (6): 617-625. 1 January 2005

Molekularmedizinische Grundlagen von fetalen und neonatalen Erkrankungen.
Ganten, D and Ruckpaul, K and Wauer, RR, eds.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-20138-6 1 January 2005

Prevention of cardiac remodeling after myocardial infarction in transgenic rats deficient in brain angiotensinogen.
Lal, A. and Veinot, J.P. and Ganten, D. and Leenen, F.H.H.
Journal of Molecular and Cellular Cardiology 39 (3): 521-529. 1 January 2005

Roles of nitric oxide and oxidative stress in the regulation of blood pressure and renal function in prehypertensive Ren-2 transgenic rats.
Vaneckova, I. and Kramer, H.J. and Novotna, J. and Kazdova, L. and Opocensky, M. and Bader, M. and Ganten, D. and Cervenka, L.
Kidney and Blood Pressure Research 28 (2): 117-126. 1 January 2005

2004

Differential regulation of central vasopressin receptors in transgenic rats with low brain angiotensinogen.
Campos, L.A. and Couto, A.S. and Iliescu, R. and Santos, J.A. and Santos, R.A.S. and Ganten, D. and Campagnole-Santos, M.J. and Bader, M. and Baltatu, O.
Regulatory Peptides 119 (3): 177-182. 15 July 2004

Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs, R.A. and Weinstock, G.M. and Metzker, M.L. and Muzny, D.M. and Sodergren, E.J. and Scherer, S. and Scott, G. and Steffen, D. and Worley, K.C. and Burch, P.E. and Okwuonu, G. and Hines, S. and Lewis, L. and DeRamo, C. and Delgado, O. and Dugan-Rocha, S. and Miner, G. and Morgan, M. and Hawes, A. and Gill, R. and Holt, R.A. and Adams, M.D. and Amanatides, P.G. and Baden-Tillson, H. and Barnstead, M. and Chin, S. and Evans, C.A. and Ferriera, S. and Fosler, C. and Glodek, A. and Gu, Z. and Jennings, D. and Kraft, C.L. and Nguyen, T. and Pfannkoch, C.M. and Sitter, C. and Sutton, G.G. and Venter, J.C. and Woodage, T. and Smith, D. and Lee, H.M. and Gustafson, E. and Cahill, P. and Kana, A. and Doucette-Stamm, L. and Weinstock, K. and Fechtel, K. and Weiss, R.B. and Dunn, D.M. and Green, E.D. and Blakesley, R.W. and Bouffard, G.G. and de Jong, P.J. and Osoegawa, K. and Zhu, B. and Marra, M. and Schein, J. and Bosdet, I. and Fjell, C. and Jones, S. and Krzywinski, M. and Mathewson, C. and Siddiqui, A. and Wye, N. and McPherson, J. and Zhao, S. and Fraser, C.M. and Shetty, J. and Shatsman, S. and Geer, K. and Chen, Y. and Abramzon, S. and Nierman, W.C. and Havlak, P.H. and Chen, R. and Durbin, K.J. and Egan, A. and Ren, Y. and Song, X.Z. and Li, B. and Liu, Y. and Qin, X. and Cawley, S. and Worley, K.C. and Cooney, A.J. and D'Souza, L.M. and Martin, K. and Wu, J.Q. and Gonzalez-Garay, M.L. and Jackson, A.R. and Kalafus, K.J. and McLeod, M.P. and Milosavljevic, A. and Virk, D. and Volkov, A. and Wheeler, D.A. and Zhang, Z. and Bailey, J.A. and Eichler, E.E. and Tuzun, E. and Birney, E. and Mongin, E. and Ureta-Vidal, A. and Woodwark, C. and Zdobnov, E. and Bork, P. and Suyama, M. and Torrents, D. and Alexandersson, M. and Trask, B.J. and Young, J.M. and Huang, H. and Wang, H. and Xing, H. and Daniels, S. and Gietzen, D. and Schmidt, J. and Stevens, K. and Vitt, U. and Wingrove, J. and Camara, F. and Alba, M.M. and Abril, J.F. and Guigo, R. and Smit, A. and Dubchak, I. and Rubin, E.M. and Couronne, O. and Poliakov, A. and Huebner, N. and Ganten, D. and Goesele, C. and Hummel, O. and Kreitler, T. and Lee, Y.A. and Monti, J. and Schulz, H. and Zimdahl, H. and Himmelbauer, H. and Lehrach, H. and Jacob, H.J. and Bromberg, S. and Gullings-Handley, J. and Jensen-Seaman, M.I. and Kwitek, A.E. and Lazar, J. and Pasko, D. and Tonellato, P.J. and Twigger, S. and Ponting, C.P. and Duarte, J.M. and Rice, S. and Goodstadt, L. and Beatson, S.A. and Emes, R.D. and Winter, E.E. and Webber, C. and Brandt, P. and Nyakatura, G. and Adetobi, M. and Chiaromonte, F. and Elnitski, L. and Eswara, P. and Hardison, R.C. and Hou, M. and Kolbe, D. and Makova, K. and Miller, W. and Nekrutenko, A. and Riemer, C. and Schwartz, S. and Taylor, J. and Yang, S. and Zhang, Y. and Lindpaintner, K. and Andrews, T.D. and Caccamo, M. and Clamp, M. and Clarke, L. and Curwen, V. and Durbin, R. and Eyras, E. and Searle, S.M. and Cooper, G.M. and Batzoglou, S. and Brudno, M. and Sidow, A. and Stone, E.A. and Venter, J.C. and Payseur, B.A. and Bourque, G. and Lopez-Otin, C. and Puente, X.S. and Chakrabarti, K. and Chatterji, S. and Dewey, C. and Pachter, L. and Bray, N. and Yap, V.B. and Caspi, A. and Tesler, G. and Pevzner, P.A. and Haussler, D. and Roskin, K.M. and Baertsch, R. and Clawson, H. and Furey, T.S. and Hinrichs, A.S. and Karolchik, D. and Kent, W.J. and Rosenbloom, K.R. and Trumbower, H. and Weirauch, M. and Cooper, D.N. and Stenson, P.D. and Ma, B. and Brent, M. and Arumugam, M. and Shteynberg, D. and Copley, R.R. and Taylor, M.S. and Riethman, H. and Mudunuri, U. and Peterson, J. and Guyer, M. and Felsenfeld, A. and Old, S. and Mockrin, S. and Collins, F.
Nature 428 (6982): 493-521. 1 April 2004

Plasma and kidney angiotensin II levels and renal functional responses to AT1 receptor blockade in hypertensive Ren-2 transgenic rats.
Kopkan, L. and Kramer, H.J. and Huskova, Z. and Vanourkova, Z. and Baecker, A. and Bader, M. and Ganten, D. and Cervenka, L.
Journal of Hypertension 22 (4): 819-825. 1 April 2004

Integrated and sequence-ordered BAC- and YAC-based physical maps for the rat genome.
Krzywinski, M. and Wallis, J. and Goesele, C. and Bosdet, I. and Chiu, R. and Graves, T. and Hummel, O. and Layman, D. and Mathewson, C. and Wye, N. and Zhu, B. and Albracht, D. and Asano, J. and Barber, S. and Brown-John, M. and Chan, S. and Chand, S. and Cloutier, A. and Davito, J. and Fjell, C. and Gaige, T. and Ganten, D. and Girn, N. and Guggenheimer, K. and Himmelbauer, H. and Kreitler, T. and Leach, S. and Lee, D. and Lehrach, H. and Mayo, M. and Mead, K. and Olson, T. and Pandoh, P. and Prabhu, A.L. and Shin, H. and Taenzer, S. and Thompson, J. and Tsai, M. and Walker, J. and Yang, G. and Sekhon, M. and Hillier, L. and Zimdahl, H. and Marziali, A. and Osoegawa, K. and Zhao, S. and Siddiqui, A. and de Jong, P.J. and Warren, W. and Mardis, E. and McPherson, J.D. and Wilson, R. and Huebner, N. and Jones, S. and Marra, M. and Schein, J.
Genome Research 14 (4): 766-779. April 2004

Alterations in sympathetic ganglionic transmission in response to angiotensin II in (mRen2)27 transgenic rats.
Aileru, A.A. and Logan, E. and Callahan, M. and Ferrario, C.M. and Ganten, D. and Diz, D.I.
Hypertension 43 (2): 270-275. February 2004

A SNP map of the rat genome generated from cDNA sequences.
Zimdahl, H. and Nyakatura, G. and Brandt, P. and Schulz, H. and Hummel, O. and Fartmann, B. and Brett, D. and Droege, M. and Monti, J. and Lee, Y.A. and Sun, Y.Y. and Zhao, S.Y. and Winter, E.E. and Ponting, C.P. and Chen, Y. and Kasprzyk, A. and Birney, E. and Ganten, D. and Huebner, N.
Science 303 (5659): 807-807. 1 January 2004

Acute effects of cyclooxygenase-2 inhibition on renal function in heterozygous Ren-2-transgenic rats on normal or low sodium intake.
Vaneckova, I. and Cahova, M. and Kramer, H.J. and Huskova, Z. and Skaroupkova, P. and Komers, R. and Bader, M. and Ganten, D. and Cervenka, L.
Kidney and Blood Pressure Research 27 (4): 203-210. 1 January 2004

Blockade of endothelin receptors attenuates end-organ damage in homozygous hypertensive Ren-2 transgenic rats.
Dvorak, P. and Kramer, H.J. and Baecker, A. and Maly, J. and Kopkan, L. and Vaneckova, I. and Vernerova, Z. and Opocensky, M. and Tesar, V. and Bader, M. and Ganten, D. and Janda, J. and Cervenka, L.
Kidney and Blood Pressure Research 27 (4): 248-258. 1 January 2004

Chronic endothelin receptor blockade reduces end-organ damage independently of blood pressure effects in salt-loaded heterozygous Ren-2 transgenic rats.
Opocensky, M. and Dvorak, P. and Maly, J. and Kramer, H.J. and Baecker, A. and Kopkan, L. and Vernerova, Z. and Tesar, V. and Zima, T. and Bader, M. and Ganten, D. and Janda, J. and Vaneckova, I.
Physiological Research 53 (6): 581-593. 1 January 2004

Das estnische Genomprojekt im Kontext der europaeischen Genomforschung [The Estonian Genome Project in the context of European genome research].
Metspalu, A. and Koehler, F. and Laschinski, G. and Ganten, D. and Roots, I.
Deutsche Medizinische Wochenschrift 129 : S25-S28. 1 January 2004

Efficiency of transgenic rat production is independent of transgene-construct and overnight embryo culture.
Popova, E. and Krivokharchenko, A. and Ganten, D. and Bader, M.
Theriogenology 61 (7-8): 1441-1453. 1 January 2004

Molecular analysis of the sex hormone-binding globulin gene in the rat hypodactylous mutation (Hd).
Liska, F. and Goesele, C. and Kren, V. and Huebner, N. and Krenova, D.
Folia Biologica Prague 50 (2): 63-68. 1 January 2004

Molekularmedizinische Grundlagen von altersspezifischen Erkrankungen.
Ganten, D. and Ruckpaul, K. and Ruiz-Torres, A.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-00858-6 1 January 2004

Prevention of sympathetic and cardiac dysfunction after myocardial infarction in transgenic rats deficient in brain angiotensinogen.
Wang, H. and Huang, B.S. and Ganten, D. and Leenen, F.H.H.
Circulation Research 94 (6): 843-849. 1 January 2004

Transgenics of the RAS.
Bader, M. and Ganten, D.
In: Angiotensin, Vol. 1. Handbook of Experimental Pharmacology ; 163, 1 . Springer, Berlin [u.a.], 229-249. ISBN 3-540-40640-9 1 January 2004

Central depletion of angiotensinogen is associated with elevated AT1 receptors in the SFO and PVN.
Kasper, S.O. and Ferrario, C.M. and Ganten, D. and Diz, D.I.
Neurotoxicity Rresearch 6 (4): 259-265. 2004

2003

Lipoic acid supplementation prevents angiotensin II-induced renal injury.
Mervaala, E. and Finckenberg, P. and Lapatto, R. and Mueller, D.N. and Park, J.K. and Dechend, R. and Ganten, D. and Vapaatalo, H. and Luft, F.C.
Kidney International 64 (2): 501-508. August 2003

Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways.
Finckenberg, P. and Inkinen, K. and Ahonen, J. and Merasto, S. and Louhelainen, M. and Vapaatalo, H. and Mueller, D. and Ganten, D. and Luft, F.C. and Mervaala, E.
American Journal of Pathology 163 (1): 355-366. July 2003

Genome-wide linkage reveals a locus for human essential (primary) hypertension on chromosome 12p.
Gong, M. and Zhang, H.Y. and Schulz, H. and Lee, Y.A. and Sun, K. and Bähring, S. and Luft, F.C. and Nuernberg, P. and Reis, A. and Rohde, K. and Ganten, D. and Hui, R.T. and Huebner, N.
Human Molecular Genetics 12 (11): 1273-1277. 1 June 2003

Entwicklung eines genetischen Markersystems fuer das Rattengenom.
Rossmann, M.
UNSPECIFIED thesis, UNSPECIFIED. 11 April 2003

The role of Wnk4 in polygenic hypertension - A candidate gene analysis on rat chromosome 10.
Monti, J. and Zimdahl, H. and Schulz, H. and Plehm, R. and Ganten, D. and Huebner, N.
Hypertension 41 (4): 938-942. April 2003

Development of parthenogenetic rat embryos.
Krivokharchenko, A. and Popova, E. and Zaitseva, I. and Vil'ianovich, L. and Ganten, D. and Bader, M.
Biology of Reproduction 68 (3): 829-836. 1 March 2003

Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure.
Gotthardt, M. and Hammer, R.E. and Huebner, N. and Monti, J. and Witt, C.C. and McNabb, M. and Richardson, J.A. and Granzier, H. and Labeit, S. and Herz, J.
Journal of Biological Chemistry 278 (8): 6059-6065. 21 February 2003

Berlin - Stadt des Wissens? Deutschland braucht einen erlebbaren Ort der neuen humanen Wissensgesellschaft.
Ganten, D.
In: Berlin - was ist uns die Hauptstadt wert? Leske + Budrich, Opladen, 95-105. ISBN 3-8100-4054-1 1 January 2003

Congenic strains confirm the presence of salt-sensitivity QTLs on chromosome 1 in the Sabra rat model of hypertension.
Yagil, C. and Hubner, N. and Kreutz, R. and Ganten, D. and Yagil, Y.
Physiological Genomics 12 : 85-95. 1 January 2003

Grundlagen der Molekularen Medizin.
Ganten, D. and Ruckpaul, K.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-43207-8 1 January 2003

Interaction between blood pressure quantitative trait loci in rats in which trait variation at chromosome 1 is conditional upon a specific allele at chromosome 10.
Monti, J. and Plehm, R. and Schulz, H. and Ganten, D. and Kreutz, R. and Huebner, N.
Human Molecular Genetics 12 (4): 435-439. 1 January 2003

Leben, Natur, Wissenschaft : Alles was man wissen muss.
Ganten, D. and Deichmann, T. and Spahl, T.
Eichborn, Frankfurt/a.M.. ISBN 3-8218-3981-3 1 January 2003

Molekularmedizinische Grundlagen von haematologischen Neoplasien.
Ganten, D. and Ruckpaul, K.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-41640-4 1 January 2003

Molekularmedizinische Grundlagen von rheumatischen Erkrankungen.
Ganten, D. and Ruckpaul, K.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-41640-4 1 January 2003

Stammzellen.
Wormer, E.J. and Kaufmann, W. and Ganten, D. and Kempermann, G.
Themen der Zeit . Lingen Verl., Koeln. ISBN 3-937490-00-0 1 January 2003

Vorwort zu "Gentherapie: Hoffnungen und Hindernisse".
Ganten, D.
In: Gentherapie : Hoffnungen und Hindernisse. Strauss, Potsdam, 8-15. ISBN 3-929748-27-4 1 January 2003

Gezielte Zellvermehrung und spezifische Zelltransplantation. Ein Plaedoyer fuer die Stammzellforschung und fuer eine Klaerung der Begrifflichkeiten.
Ganten, D.
Zeitschrift fuer Biopolitik 2 (1): 25-33. 2003

2002

How to deal with scientific controversy?
Ganten, D.
Journal of Molecular Medicine 80 (12): 745-746. December 2002

Comparison between PMSG- and FSH-induced superovulation for the generation of transgenic rats.
Popova, E. and Krivokharchenko, A. and Ganten, D. and Bader, M.
Molecular Reproduction and Development 63 (2): 177-182. October 2002

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Oezcelik, C. and Erdmann, B. and Pilz, B. and Wettschureck, N. and Britsch, S. and Huebner, N. and Chien, K.R. and Birchmeier, C. and Garratt, A.N.
Proceedings of the National Academy of Sciences of the United States of America 99 (13): 8880-8885. 25 June 2002

Verwendung von aus embryonalen Stammzellen hergeleiteten Zellen zur Erhoehung der Transplantationstoleranz und zur Wiederherstellung zerstoerten Gewebes [Use of cells derived from embryonic stem cells for increasing transplantation tolerance and for repairing damaged tissue].
Bader, M. and Binas, B. and Chai, G. and Faendrich, F. and Ganten, D. and Lin, X.
DE10061334A1 ; EP1341915 ; WO0246401. 13 June 2002

Conserved synteny in rat and mouse for a blood pressure QTL on human chromosome 17.
Zimdahl, H. and Kreitler, T. and Goesele, C. and Ganten, D. and Huebner, N.
Hypertension 39 (6): 1050-1052. 1 June 2002

Reduced hypertension-induced end-organ damage in mice lacking cardiac and renal angiotensinogen synthesis.
Kang, N.L. and Walther, T. and Tian, X.L. and Bohlender, J. and Fukamizu, A. and Ganten, D. and Bader, M.
Journal of Molecular Medicine 80 (6): 359-366. June 2002

Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen.
Couto, A.S. and Baltatu, O. and Santos, R.A.S. and Ganten, D. and Bader, M. and Campagnole-Santos, M.J.
Journal of Hypertension 20 (5): 919-925. May 2002

Friedrich Cameron Luft turns 60: bridging the New and the Old World.
Ganten, D.
Journal of Molecular Medicine 80 (4): 197-199. April 2002

Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioning.
Faendrich, F. and Lin, X. and Chai, G.X. and Schulze, M. and Ganten, D. and Bader, M. and Holle, J. and Huang, D.S. and Parwaresch, R. and Zavazava, N. and Binas, B.
Nature Medicine 8 : 171-178. 1 February 2002

Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats.
Theuer, J. and Dechend, R. and Muller, D.N. and Park, J.K. and Fiebeler, A. and Barta, P. and Ganten, D. and Haller, H. and Dietz, R. and Luft, F.C.
BMC Cardiovascular Disorders 2 : 3. 18 January 2002

A gene expression analysis in rat kidney following high and low salt intake.
Barta, P. and Monti, J. and Maass, P.G. and Gorzelniak, K. and Mueller, D.N. and Dechend, R. and Luft, F.C. and Huebner, N. and Sharma, A.M.
Journal of Hypertension 20 : 1115-1120. 1 January 2002

Congenic rat strains are important tools for the genetic dissection of essential hypertension.
Kreutz, R. and Huebner, N.
Seminars in Nephrology 22 (2): 135-147. 1 January 2002

Decreased susceptibility of cardiac function to hypoxia-reoxygenation in renin-angiotensinogen transgenic rats.
Wagner, K.D. and Essmann, V. and Mydlak, K. and Wirth, M. and Gmehling, G. and Bohlender, J. and Stauss, H.M. and Gunther, J. and Schimke, I. and Scholz, H.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 283 (1): R153-R160. 1 January 2002

In vitro formation of tetraploid rat blastocysts after fusion of two-cell embryos.
Krivokharchenko, A. and Galat, V. and Ganten, D. and Bader, M.
Molecular Reproduction and Development 61 (4): 460-465. 1 January 2002

It's renin in the brain - Transgenic animals elucidate the brain renin-angiotensin system.
Bader, M. and Ganten, D.
Circulation Research 90 (1): 8-10. 1 January 2002

Molekularmedizinische Grundlagen von nicht-hereditaeren Tumorerkrankungen.
Ganten, D. and Ruckpaul, K.
Molekulare Medizin, 10 . Springer, Berlin [u.a.]. ISBN 3-540-41577-7 1 January 2002

TNF-alpha-accelerated apoptosis abrogates ANCA-mediated neutrophil respiratory burst by a caspase-dependent mechanism.
Kettritz, R. and Scheumann, J. and Xu, Y.X. and Luft, F.C. and Haller, H.
Kidney International 61 : 502-515. 1 January 2002

A prospective evaluation of the angiotensin-converting enzyme D/I polymorphism and left ventricular remodeling in the 'Healing and Early Afterload Reducing Therapy' Study.
Zee, R.Y.L. and Solomon, S.D. and Ajani, U.A. and Pfeffer, M.A. and Lindpaintner, K.
Clinical Genetics 61 (1): 21-25. January 2002

Genomforschung und Biotechnologie in Deutschland.
Ganten, D.
In: Komplexe Langzeitvertraege fuer neue Technologien und neue Projekte. Heidelberger Kolloquium Technologie und Recht 2001. Beck, Muenchen, 55-61. ISBN 9783406497155 2002

Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.
Cervenka, L. and Kramer, H.J. and Maly, J. and Vaneckova, I. and Baecker, A. and Bokemeyer, D. and Bader, M. and Ganten, D. and Mitchell, K.D.
Physiological Research 51 (6): 571-580. 2002

2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 79 (7): 353-354. July 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 79 (5-6): 224-225. June 2001

The Future of Molecular Medicine. 4th Berlin Colloquium of the Gottlieb Daimler and Karl Benz Foundation in co-operation with the Max Delbruck Center for Molecular Medicine (MDC), Berlin-Buch, on Wednesday, May 10, 2000 in Berlin at the Konrad Adenauer Fundation, Tiergartenstr. 35, D-10785 Berlin.
Ganten, D.
Molecular Aspects of Medicine 22 (3): 91-100. June 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 79 (4): 159-160. May 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 79 (2-3): 74-75. April 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 79 (1): 4-5. March 2001

Alterations in blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen.
Baltatu, O. and Janssen, B.J. and Bricca, G. and Plehm, R. and Monti, J. and Ganten, D. and Bader, M.
Hypertension 37 (2): 408-413. 1 January 2001

Alterations of the renin-angiotensin system at the RVLM of transgenic rats with low brain angiotensinogen.
Baltatu, O. and Fontes, M.A.P. and Campagnole-Santos, M.J. and Caligiorni, S. and Ganten, D. and Santos, R.A.S. and Bader, M.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 280 (2): R428-R433. 1 January 2001

Aspirin inhibits NF-kappa B and protects from angiotensin II-induced organ damage.
Mueller, D.N. and Heissmeyer, V. and Dechend, R. and Hampich, F. and Park, J.K. and Fiebeler, A. and Shagdarsuren, E. and Theuer, J. and Elger, M. and Pilz, B. and Breu, V. and Schroer, K. and Ganten, D. and Dietz, R. and Haller, H. and Scheidereit, C. and Luft, F.C.
FASEB Journal 15 : 1822-1824. 1 January 2001

Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes.
Mervaala, E.M.A. and Cheng, Z.J. and Tikkanen, I. and Lapatto, R. and Nurminen, K. and Vapaatalo, H. and Mueller, D.N. and Fiebeler, A. and Ganten, U. and Ganten, D. and Luft, F.C.
Hypertension 37 (2): 414-418. 1 January 2001

Expression analysis using oligonucleotide microarrays in mice lacking bradykinin type 2 receptors.
Monti, J. and Gross, V. and Luft, F.C. and Milia, A.F. and Schulz, H. and Dietz, R. and Sharma, A.M. and Huebner, N.
Hypertension 38 (1): E1-E3. 1 January 2001

Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN).
Monti, J. and Schinke, M. and Boehm, M. and Ganten, D. and Bader, M. and Bricca, G.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 280 (1): R233-R240. 1 January 2001

Induction of hippocampal glial cells expressing basic fibroblast growth factor RNA by corticosterone.
Hansson, A.C. and Sommer, W. and Andbjer, B. and Bader, M. and Ganten, D. and Fuxe, K.
NeuroReport 12 (1): 141-145. 1 January 2001

Molekularmedizinische Grundlagen von Endokrinopathien.
Ganten, D. and Ruckpaul, K. and Janssen, O.E. and Heufelder, A.E.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-67788-7 1 January 2001

Molekularmedizinische Grundlagen von heriditaeren Tumorerkrankungen.
Ganten, D. and Ruckpaul, K.
Molekulare Medizin, Handbuch der Molekularen Medizin ; 9 . Springer, Berlin [u.a.]. ISBN 3-540-67808-5 1 January 2001

Naturwissenschaft und Medizin - Interdisziplinaritaet des Denkens und der Strukturen.
Ganten, D.
In: Innere Medizin am Uebergang in das 3. Jahrtausend. 26. Symposium der Gesellschaft fuer Fortschritte in der Inneren Medizin. Schriftenreihe der Gesellschaft fuer Fortschritte in der Inneren Medizin . Thieme, Stuttgart; New York, 51-55. ISBN 3-13-105841-2 1 January 2001

Overexpression of the human angiotensin II type 1 receptor in the rat heart augments load induced cardiac hypertrophy.
Hoffmann, S. and Krause, T. and van Geel, P.P. and Willenbrock, R. and Pagel, I. and Pinto, Y.M. and Buikema, H. and van Gilst, W.H. and Lindschau, C. and Paul, M. and Inagami, T. and Ganten, D. and Urata, H.
Journal of Molecular Medicine 79 (10): 601-608. 1 January 2001

Responses to central Na+ and ouabain are attenuated in transgenic rats deficient in brain angiotensinogen.
Huang, B.S. and Ganten, D. and Leenen, F.H.H.
Hypertension 37 (2): 683-686. 1 January 2001

Sequence interpretation - Functional annotation of mouse genome sequences.
Nadeau, J.H. and Balling, R. and Barsh, G. and Beier, D. and Brown, S.D.M. and Bucan, M. and Camper, S. and Carlson, G. and Copeland, N. and Eppig, J. and Fletcher, C. and Frankel, W.N. and Ganten, D. and Goldowitz, D. and Goodnow, C. and Guenet, J.L. and Hicks, G. and de Angelis, M.H. and Jackson, I. and Jacob, H.J. and Jenkins, N. and Johnson, D. and Justice, M. and Kay, S. and Kingsley, D. and Lehrach, H. and Magnuson, T. and Meisler, M. and Poustka, A.M. and Rinchik, E.M. and Rossant, J. and Russell, L.B. and Schimenti, J. and Shiroishi, T. and Skarnes, W.C. and Soriano, P. and Stanford, W. and Takahashi, J.S. and Wurst, W. and Zimmer, A.
Science 291 : 1251-1255. 1 January 2001

Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research.
Bader, M. and Peters, J. and Baltatu, O. and Mueller, D.N. and Luft, F.C. and Ganten, D.
Journal of Molecular Medicine 79 (2): 76-102. 1 January 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 78 (11): 592-593. January 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 78 (12): 661-662. 2001

Woher kommt der Mensch? Wo steht der Mensch? Wohin geht der Mensch?
Ganten, D.
Humboldt-Spektrum 2001 (3-4): 6-9. 2001

2000

Monocyte chemoattractant protein-1 and macrophage infiltration in hypertensive kidney injury.
Hilgers, K.F. and Hartner, A. and Porst, M. and Mai, M. and Wittmann, M. and Hugo, C. and Ganten, D. and Geiger, H. and Veelken, R. and Mann, J.F.E.
Kidney International 58 : 2408-2419. 1 December 2000

High-throughput scanning of the rat genome using interspersed repetitive sequence-PCR markers.
Gosele, C. and Hong, L. and Kreitler, T. and Rossmann, M. and Hieke, B. and Gross, U. and Kramer, M. and Himmelbauer, H. and Bihoreau, M.T. and Kwitek-Black, A.E. and Twigger, S. and Tonellato, P.J. and Jacob, H.J. and Schalkwyk, L.C. and Lindpaintner, K. and Ganten, D. and Lehrach, H. and Knoblauch, M.
Genomics 69 (3): 287-294. 1 November 2000

Rats transgenic for human renin and human angiotensinogen as a model for gestational hypertension.
Bohlender, J. and Ganten, D. and Luft, F.C.
Journal of the American Society of Nephrology 11 (11): 2056-2061. 1 November 2000

Transgenic animals in cardiovascular disease research.
Bader, M. and Bohnemeier, H. and Zollmann, F.S. and Lockley-Jones, O.E. and Ganten, D.
Experimental Physiology 85 (6): 713-731. 1 November 2000

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 78 (9): 472. November 2000

Cerivastatin prevents angiotensin II-induced renal injury independent of blood pressure- and cholesterol-lowering effects.
Park, J.K. and Mueller, D.N. and Mervaala, E.M.A. and Dechend, R. and Fiebeler, A. and Schmidt, F. and Bieringer, M. and Schaefer, O. and Lindschau, C. and Schneider, W. and Ganten, D. and Luft, F.C. and Haller, H.
Kidney International 58 (4): 1420-1430. 1 October 2000

Reduced cardiac hypertrophy and altered blood pressure control in transgenic rats with the human tissue kallikrein gene.
Silva, J.A. and Araujo, R.C. and Baltatu, O. and Oliveira, S.M. and Tschoepe, C. and Fink, E. and Hoffmann, S. and Plehm, R. and Chai, K.X. and Chao, L. and Chao, J. and Ganten, D. and Pesquero, J.B. and Bader, M.
FASEB Journal 14 (13): 1858-1860. 1 October 2000

JMM and medical science, past and present.
Ganten, D. and Vogt, P.K.
Journal of Molecular Medicine 78 (8): 397-399. October 2000

Purification and identification of p92, a sequence-specific nuclear factor interacting with the enhancer of the human papillomavirus type 18 (HPV 18).
Jia, W.
UNSPECIFIED thesis, UNSPECIFIED. 25 August 2000

Effect of Bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage.
Muller, D.N. and Mervaala, E.M.A. and Schmidt, F. and Park, J.K. and Dechend, R. and Genersch, E. and Breu, V. and Loeffler, B.M. and Ganten, D. and Schneider, W. and Haller, H. and Luft, F.C.
Hypertension 36 (2): 282-290. 1 August 2000

Gluco- and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat.
Hansson, A.C. and Cintra, A. and Belluardo, N. and Sommer, W. and Bhatnagar, M. and Bader, M. and Ganten, D. and Fuxe, K.
European Journal of Neuroscience 12 (8): 2918-2934. 1 August 2000

Angiotensin II (AT1) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy.
Mueller, D.N. and Mervaala, E.M.A. and Dechend, R. and Fiebeler, A. and Park, J.K. and Schmidt, F. and Theuer, J. and Breu, V. and Mackman, N. and Luther, T. and Schneider, W. and Gulba, D. and Ganten, D. and Haller, H. and Luft, F.C.
American Journal of Pathology 157 : 111-122. 1 July 2000

Genetisches Wissen fuer Gesundheit und Krankheit [Genetic knowledge for health and disease].
Ganten, D. and Ruckpaul, K.
Nachrichten aus der Chemie 48 (7-8): 894-902. July 2000

Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats.
Fontes, M.A.P. and Baltatu, O. and Caligiorne, S.M. and Campagnole-Santos, M.J. and Ganten, D. and Bader, M. and Santos, R.A.S.
Physiological Genomics 2 : 137-142. 27 April 2000

Distinguished scientists back Germany's DFG . .
Jahn, R. and Boeck, A. and Breiner, K.M. and Breunig, K.D. and Bujard, H. and Campos-Ortega, J. and Ganten, D. and Grummt, I. and Gruss, P. and Goridis, C. and Huber, R. and Hoch, M. and Jaeckle, H. and Kahmann, R. and Koch-Brandt, C. and Leptin, M. and Michel, H. and Noegel, A. and Neher, E. and Nuesslein-Volhard, C. and Pfanner, N. and Sandhoff, K. and Schoen, A. and Schwille, P. and Simons, K. and Zrenner, E.
Nature 404 : 922-922. 27 April 2000

Defective suppression of the aldosterone biosynthesis during stroke permissive diet in the stroke-prone phenotype of the spontaneously hypertensive rat.
Enea, I. and De Paolis, P. and Porcellini, A. and Piras, O. and Savoia, C. and Russo, R. and Giliberti, R. and Gigante, B. and Rubattu, S. and Conte, G. and Ganten, D. and Volpe, M.
Basic Research in Cardiology 95 (2): 84-92. 1 April 2000

New tools for the high throughput characterization of rat genomic DNA samples.
Knoblauch, M. and Goesele, C. and Zimdahl, H. and Hieke, B. and Himmelbauer, H. and Schalkwyk, L. and Lindpaintner, K. and Ganten, D. and Lehrach, H.
Journal of Experimental Animal Science 41 (1-2): 35-37. 1 March 2000

Blood pressure-independent effects in rats with human renin and angiotensinogen genes.
Mervaala, E. and Mueller, D.N. and Schmidt, F. and Park, J.K. and Gross, V. and Bader, M. and Breu, V. and Ganten, D. and Haller, H. and Luft, F.C.
Hypertension 35 (2): 587-594. 1 February 2000

Angiotensinogen concentrations and renin clearance. Implications for blood pressure regulation.
Bohlender, J. and Menard, J. and Ganten, D. and Luft, F.C.
Hypertension 35 : 780-786. 1 January 2000

Assignment of the kinin receptor B1 and B2 genes (Bdkrb1 and Bdkrb2) to rat chromosome 6q3.2 by FISH and radiation hybrid mapping.
Goesele, C. and Gruetzner, F. and Pesquero, J.B. and Silva, J.A. and Junge, T. and Ganten, D. and Bader, M. and Knoblauch, M.
Cytogenetics and Cell Genetics 89 (1-2): 51-52. 1 January 2000

Campus Berlin-Buch.
Ganten, D.
In: Das Neue Berlin : Perspektiven fuer das 21. Jahrhundert. Monographien deutscher Wirtschaftsgebiete . Kommunikation u. Wirtschaft, Oldenburg, 96-101. ISBN 3-88363-186-8 1 January 2000

Comment on "the prickly pear".
Ganten, D.
Journal of Molecular Medicine 78 (8): 403. 1 January 2000

Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes.
Mervaala, E. and Mueller, D.N. and Park, J.K. and Dechend, R. and Schmidt, F. and Fiebeler, A. and Bieringer, M. and Breu, V. and Ganten, D. and Haller, H. and Luft, F.C.
Hypertension 35 (1): 360-366. 1 January 2000

Entdeckung und Erfindung : Genomforschung in Deutschland: zu wenig Geld, unsichere Rechtslage.
Ganten, D.
Berliner Republik 4 : 7-9. 1 January 2000

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 78 (10): 541-542. 1 January 2000

Monogen bedingte Erbkrankheiten 1.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 6 . Springer, Berlin [u.a.]. ISBN 3-540-65529-8 1 January 2000

Monogen bedingte Erbkrankheiten 2.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 7 . Springer, Berlin [u.a.]. ISBN 3-540-65530-1 1 January 2000

NF-kappaB Inhibition Ameliorates Angiotensin II-Induced Inflammatory Damage in Rats.
Muller, D.N. and Dechend, R. and Mervaala, E.M.A. and Park, J.K. and Schmidt, F. and Fiebeler, A. and Theuer, J. and Breu, V. and Ganten, D. and Haller, H. and Luft, F.C.
Hypertension 35 (1): 193-201. 1 January 2000

Regulation of renin: new evidence from cultured cells and genetically modified mice.
Bader, M. and Ganten, D.
Journal of Molecular Medicine 78 (3): 130-139. 1 January 2000

The brain renin-angiotensin system modulates angiotensin II-induced hypertension and cardiac hypertrophy.
Baltatu, O. and Silva, J.A. and Ganten, D. and Bader, M.
Hypertension 35 (1): 409-412. 1 January 2000

1999

Myokardiale Dysfunktion in transgenen Ratten mit Humanrenin-induzierter arterieller Hypertonie: Phaenotypische Charakteristiken und pathogenetische Ursachen.
Hildenbrand, U.
UNSPECIFIED thesis, UNSPECIFIED. 25 December 1999

The central renin angiotensin system in blood pressure regulation: Examinations in transgenic rat strains TGR(mRen2)27 and TGR(ASrAOGEN) [Das zentrale Renin-Angiotensin-System in der Regulation des Blutdruckes: Untersuchungen an transgenen Ratten TGR(mRen2)27 und TGR(ASrAOGEN)].
Monti, J.
UNSPECIFIED thesis, UNSPECIFIED. 25 December 1999

Differential brain atrial natriuretic peptide expression co-segregates with occurrence of early stroke in the stroke-prone phenotype of the spontaneously hypertensive rat.
Rubattu, S. and Giliberti, R. and Ganten, U. and Volpe, M.
Journal of Hypertension 17 (12 Pt 2): 1849-1852. December 1999

Hemodynamics and metabolism in stroke-prone spontaneously hypertensive rats before manifestation of brain infarcts.
Mies, G. and Hermann, D. and Ganten, U. and Hossmann, K.A.
Journal of Cerebral Blood Flow and Metabolism 19 (11): 1238-1246. November 1999

Enhanced blood pressure buffering role of the brain nitrergic system in renin transgenic rats.
Lon, S. and Szczepanska-Sadowska, E. and Paczwa, P. and Ganten, D.
Brain Research 842 : 384-391. 25 September 1999

Angiotensin-converting enzyme inhibition and AT1 receptor blockade modify the pressure-natriuresis relationship by additive mechanisms in rats with human renin and angiotensinogen genes.
Mervaala, E. and Dehmel, B. and Gross, V. and Lippoldt, A. and Bohlender, J. and Milia, A.F. and Ganten, D. and Luft, F.C.
Journal of the American Society of Nephrology 10 : 1669-1680. 1 August 1999

Online first publication.
Ganten, D. and Lange, R.
Journal of Molecular Medicine 77 : 455. 1 June 1999

Role of central AT1 and V1 receptors in cardiovascular adaptation to hemorrhage in SD and renin TGR rats.
Paczwa, P. and Szczepanska-Sadowska, E. and Lont, S. and Ganten, U. and Ganten, D.
American Journal of Physiology Heart and Circulatory Physiology 45 : H1918-H1926. 1 June 1999

Interstrain differences in angiotensin I-converting enzyme mRNA and activity levels. Comparison between stroke-prone spontaneously hypertensive rats and Wistar-Kyoto rats.
Costerousse, O. and Lindpaintner, K. and Paul, M. and Ganten, D. and Kreutz, R.
Clinical and Experimental Hypertension 21 : 377-393. 1 May 1999

Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen.
Schinke, M. and Baltatu, O. and Boehm, M. and Peters, J. and Rascher, W. and Bricca, G. and Lippoldt, A. and Ganten, D. and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 96 : 3975-3980. 30 March 1999

Angiotensin II AT1-receptor blockade inhibits monocyte activation and adherence in transgenic (mRen2)27 rats.
Strawn, W.B. and Gallagher, P.E. and Tallant, E.A. and Ganten, D. and Ferrario, C.M.
Journal of Cardiovascular Pharmacology 33 : 341-351. 1 March 1999

Increased central angiotensin and osmotic responses in the Ren-2 transgenic rat.
Nishioka, T. and Callahan, M.F. and Li, P. and Ferrario, C.M. and Ganten, D. and Morris, M.
Hypertension 33 : 385-388. 11 January 1999

A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat.
Steen, R.G. and Kwitek-Black, A.E. and Glenn, C. and Gullings-Handley, J. and Van Etten, W. and Atkinson, O.S. and Appel, D. and Twigger, S. and Muir, M. and Mull, T. and Granados, M. and Kissebah, M. and Russo, K. and Crane, R. and Popp, M. and Peden, M. and Matise, T. and Brown, D.M. and Lu, J. and Kingsmore, S. and Tonellato, P.J. and Rozen, S. and Slonim, D. and Young, P. and Knoblauch, M. and Provoost, A. and Ganten, D. and Colman, S.D. and Rothberg, J. and Lander, E.S. and Jacob, H.J.
Genome Research 9 : 1-8. 1 January 1999

Ausgewaehlte monogen bedingte Erkrankungen. Teil 1.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 6 . Springer, Berlin [u.a.]. 1 January 1999

Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1.
Huebner, N. and Lee, Y.A. and Lindpaintner, K. and Ganten, D. and Kreutz, R.
Hypertension 34 : 643-648. 1 January 1999

Endothelial dysfunction in the aorta of transgenic rats harboring the mouse Ren-2 gene.
Arnet, U.A. and Novosel, D. and Barton, M. and Noll, G. and Ganten, D. and Luescher, T.F.
Endothelium 6 : 175-184. 1 January 1999

Erkrankungen des Zentralnervensystems.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 5 . Springer, Berlin [u.a.]. ISBN 3-540-64552-7 1 January 1999

Gene, Neurone, Qubits & Co : Unsere Welten der Information.
Ganten, D. and Meyer-Galow, E. and Ropers, H.H. and Scheich, H. and Schwarz, H. and Urban, K. and Truscheit, E.
Verhandlungen der Gesellschaft Deutscher Naturforscher und aerzte ; 120 . Hirzel, Stuttgart. 1 January 1999

Genetica dell'ipertensione arteriosa.
Endeman, D. and Paul, M. and Ganten, D.
Enciclopedia Medica Italiana 2 : 2887-2897. 1 January 1999

Hypertension-induced end-organ damage - A new transgenic approach to an old problem.
Luft, F.C. and Mervaala, E. and Mueller, D.N. and Gross, V. and Schmidt, F. and Park, J.K. and Schmitz, C. and Lippoldt, A. and Breu, V. and Dechend, R. and Dragun, D. and Schneider, W. and Ganten, D. and Haller, H.
Hypertension 33 : 212-218. 1 January 1999

Immunsystem und Infektiologie.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 4 . Springer, Berlin [u.a.]. ISBN 3-540-62464-3 1 January 1999

Monocyte infiltration and adhesion molecules in a rat model of high human renin hypertension.
Mervaala, E.M.A. and Mueller, D.N. and Park, J.K. and Schmidt, F. and Loehn, M. and Breu, V. and Dragun, D. and Ganten, D. and Haller, H. and Luft, F.C.
Hypertension 33 : 389-395. 1 January 1999

Role of chromosome X in the Sabra rat model of salt-sensitive hypertension.
Yagil, C. and Sapojnikov, M. and Kreutz, R. and Zuercher, H. and Ganten, D. and Yagil, Y.
Hypertension 33 : 261-265. 1 January 1999

Transcriptional regulation of the rat renin gene by regulatory elements in intron I.
Voigtlaender, T. and Ganten, D. and Bader, M.
Hypertension 33 : 303-311. 1 January 1999

Unsere Welten der Information : eine Einfuehrung.
Ganten, D.
In: Gene, Neurone, Qubits & Co. : Unsere Welten der Information. Verhandlungen der Gesellschaft Deutscher Naturforscher und Aerzte ; 120 . Hirzel, Stuttgart, 7-13. 1 January 1999

Report on rat chromosome 10.
Knoblauch, M. and Jacob, H. and Ganten, D. and Lindpaintner, K.
Journal of Experimental Animal Science 40 (1-3): 81-92. 1999

1998

Pressure-natriuresis and -diuresis in transgenic rats harboring both human renin and human angiotensinogen genes.
Dehmel, B. and Mervaala, E. and Lippoldt, A. and Gross, V. and Bohlender, J. and Ganten, D. and Luft, F.C.
Journal of the American Society of Nephrology 9 (12): 2212-2222. December 1998

Dual pathway for angiotensin II formation in human internal mammary arteries.
Voors, A.A. and Pinto, Y.M. and Buikema, H. and Urata, H. and Oosterga, M. and Roos, G. and Grandjean, J.G. and Ganten, D. and van Gilst, W.H.
British Journal of Pharmacology 125 : 1028-1032. 1 November 1998

Functional evidence for alternative ANG II-forming pathways in hamster cardiovascular system.
Nishimura, H. and Buikema, H. and Baltatu, O. and Ganten, D. and Urata, H.
American Journal of Physiology 275 : H1307-H1312. 1 October 1998

Increased pressor function of central vasopressinergic system in hypertensive renin transgenic rats.
Szczepanska-Sadowska, E. and Paczwa, P. and Lon, S. and Ganten, D.
Journal of Hypertension 16 : 1505-1514. 1 October 1998

Converting enzyme determines plasma clearance of angiotensin-(1-7).
Yamada, K. and Iyer, S.N. and Chappell, M.C. and Ganten, D. and Ferrario, C.M.
Hypertension 32 (3): 496-502. 1 September 1998

Lessons from rat models of hypertension: from Goldblatt to genetic engineering.
Pinto, Y.M. and Paul, M. and Ganten, D.
Cardiovascular Research 39 (1): 77-88. 1 July 1998

Local angiotensin II generation in the rat heart: role of renin uptake.
Mueller, D.N. and Fischli, W. and Clozel, J.P. and Hilgers, K.F. and Bohlender, J. and Menard, J. and Busjahn, A. and Ganten, D. and Luft, F.C.
Circulation Research 82 (1): 13-20. 9 January 1998

A transgenic rat model for Alzheimer's disease.
Ganten, D.
In: Human Genome Analysis. IOS Press, Amsterdam, 450-457. 1 January 1998

Adrenal renin expression and its role in ren-2 transgenic rats TCR(mREN2)27.
Peters, J. and Ganten, D.
Hormone and Metabolic Research 30 : 350-354. 1 January 1998

Adrenal, kidney, and heart angiotensins in female murine Ren-2 transfected hypertensive rats.
Senanayake, P.D. and Smeby, R.R. and Martins, A.S. and Moriguchi, A. and Kumagai, H. and Ganten, D. and Brosnihan, K.B.
Peptides 19 : 1685-1694. 1 January 1998

Alternative splicing of the mRNA coding for the human endothelial angiotensin-converting enzyme: a new mechanism for solubilization.
Sugimura, K. and Tian, X.L. and Hoffmann, S. and Ganten, D. and Bader, M.
Biochemical and Biophysical Research Communications 247 : 466-472. 1 January 1998

Aspekte der somatischen Gentherapie in der Herz- und Kreislaufmedizin.
von Harsdorf, R. and Dietz, R.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 37-60. 1 January 1998

Bedeutung peptiderger Systeme bei der Genese kardiovaskulaerer Erkrankungen.
Stula, M. and Schott, E. and Paul, M.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 372-400. 1 January 1998

Blick nach vorn. Ein Interview.
Ganten, D.
Gegenworte Zeitschrift fuer den Disput ueber Wissen 2 : 8-11. 1 January 1998

Cardiovascular, endocrine and body fluid-electrolyte responses to salt loading in mRen-2 transgenic rats.
Li, P. and Morris, M. and Ferrario, C.M. and Barrett, C. and Ganten, D. and Callahan, M.F.
American Journal of Physiology Heart and Circulatory Physiology 44 : H1130-H1137. 1 January 1998

Changes of blood pressure and aortic strip contractile responses to ET-1 of heterozygous female transgenic rats, TGR(mRen2)27.
Cargnelli, G. and Rossi, G.P. and Pessina, A.C. and Luciani, S. and Debetto, P. and Ganten, D. and Peters, J. and Bova, S.
Pharmacological Research 37 : 207-211. 1 January 1998

Das "Wie" und "Wozu" der klinischen Forschung.
Ganten, D.
Forum Deutsche Krebsgesellschaft eV 13 : 21-22. 1 January 1998

Depressor role of angiotensin AT2 receptors in the (mRen-2)27 transgenic rat.
Nishioka, T. and Morris, M. and Li, P. and Ganten, D. and Ferrario, C.M. and Callahan, M.F.
American Journal of Hypertension 11 : 357-362. 1 January 1998

Editorial.
Ganten, D.
Nieren- und Hochdruckkrankheiten 27 : 104-106. 1 January 1998

Effects of AT1 receptor blockade on blood pressure and the renin-angiotensin system in spontaneously hypertensive rats of the stroke prone strain.
Wagner, J. and Drab, M. and Bohlender, J. and Amann, K. and Wienen, W. and Ganten, D.
Clinical and Experimental Hypertension 20 : 205-221. 1 January 1998

Evaluation von Gesundheitsforschung - eine methodische Uebersicht: Projekte, Foerderschwerpunkte, Einrichtungen, Innovationspotential, Effizienz, Qualitaet.
Selbmann, H.K. and Ganten, D.
[s.n.], Bonn. 1 January 1998

Functional testing of components of the brain renin-angiotensin system in transgenic animals.
Baltatu, O. and Bader, M. and Ganten, D.
In: Renin-angiotensin : Proceedings from a Symposium held at the Wenner-Gren Research Institute, Stockholm, in September 1997, honouring Robert Tigerstedt and his Discovery of the Renin-angiotensin System. Wenner-Gren International Series ; 74 . Portland, London, 105-114. ISBN 1-85578-128-X 1 January 1998

Genetische Ursachen der Hypercholesterinaemie und ihre Verknuepfung mit Gefaesserkrankungen.
Schuster, H.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 325-343. 1 January 1998

Herz-Kreislauf-Erkrankungen.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.]. ISBN 3-540-62462-7 1 January 1998

Impaired vasorelaxant responses to natriuretic peptides in the stroke-prone phenotype of spontaneously hypertensive rats.
Russo, R. and Vecchione, C. and Cosentino, F. and Natale, A. and Mele, A.F. and Muscolo, M. and Savoia, C. and Ganten, D. and Rubattu, S. and Volpe, M.
Journal of Hypertension 16 : 151-156. 1 January 1998

Local renin-angiotensin system in the pineal gland.
Baltatu, O. and Lippoldt, A. and Hansson, A. and Ganten, D. and Bader, M.
Molecular Brain Research 54 : 237-242. 1 January 1998

Mapping of candidate genes for hypertension by fluorescence in situ hybridization on the genome of transgenic rats and mice.
Schmidt, C. and Ganten, D. and Klenk, A. and Buselmaier, W.
Clinical and Experimental Hypertension 20 : 185-204. 1 January 1998

Mechanismen der Angiogenese.
Haller, H. and Genersch, E. and Lenz, T. and Luft, F.C.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 308-321. 1 January 1998

Mechanismen der Entstehung genetisch bedingter Krebsformen.
Scherneck, S. and Koelble, K.
In: Tumorerkrankungen. Handbuch der Molekularen Medizin ; 2 . Springer, Berlin [u.a.], 3-26. 1 January 1998

Molekularbiologie, Klinik und Therapie steroidbedingter Hypertonien.
Peters, J. and Hampf, M. and Peters, B. and Bernhardt, R.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 413-452. 1 January 1998

Molekulare Grundlagen des Gentransfers und Anwendung fuer die Gentherapie.
Brand, K. and Strauss, M.
In: Tumorerkrankungen. Handbuch der Molekularen Medizin ; 2 . Springer, Berlin [u.a.], 110-145. 1 January 1998

Molekulare Mechanismen der zentralen Regulation von Herz-Kreislauf-Funktionen und klinisch-therapeutische Aspekte.
Lippoldt, A. and Monti, J.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 3-36. 1 January 1998

Mouse and rat plasma renin concentration and gene expression in (mRen2)27 transgenic rats.
Bohlender, J. and Menard, J. and Edling, O. and Ganten, D. and Luft, F.C.
American Journal of Physiology Heart and Circulatory Physiology 43 : H1450-H1456. 1 January 1998

NK1 receptor antagonist blocks angiotensin II responses in renin transgenic rat medulla oblongata.
Diz, D.I. and Westwood, B. and Bosch, S.M. and Ganten, D. and Ferrario, C.M.
Hypertension 31 : 473-479. 1 January 1998

Salt susceptibility maps to chromosomes 1 and 17 with sex specificity in the Sabra rat model of hypertension.
Yagil, C. and Sapojnikov, M. and Kreutz, R. and Katni, G. and Lindpaintner, K. and Ganten, D. and Yagil, Y.
Hypertension 31 : 119-124. 1 January 1998

Sustained long-term potentiation and anxiety in mice lacking the Mas protooncogene.
Walther, T. and Balschun, D. and Voigt, J.P. and Fink, H. and Zuschratter, W. and Birchmeier, C. and Ganten, D. and Bader, M.
Journal of Biological Chemistry 273 : 11867-11873. 1 January 1998

Transgene Tiere - ihre Nutzung in der Humanmedizin.
Ganten, D.
In: Gene und Klone. Moeglichkeiten sowie ethische Grenzen der Bio- und Gentechnologie bei Tieren. (Tagung fuer Fachleute aus Tiermedizin, Tierzucht, Rechtswissenschaft und Ethik. Besonders aber auch fuer Sonst im Tierschutz Engagierte vom 15. bis 17. Mai 1998. Protokolldienst / Evangelische Akademie Bad Boll; 98,20 . Evangelische Akademie Bad Boll, Bad Boll, 58-64. 1 January 1998

Tumorerkrankungen.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 2 . Springer, Berlin [u.a.]. ISBN 3-540-62463-5 1 January 1998

1997

Estrogen protects transgenic hypertensive rats by shifting the vasoconstrictor-vasodilator balance of RAS.
Brosnihan, K.B. and Li, P. and Ganten, D. and Ferrario, C.M.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 273 (6 Pt 2): R1908-R1915. 1 December 1997

Enalapril and renal function in hypertensive rats transgenic for mouse renin gene.
Springate, J.E. and Feld, L.G. and Ganten, D.
Hypertension 30 : 868-872. 1 October 1997

Evidence for primary genetic determination of heart rate regulation. Chromosomal mapping of a genetic locus in the rat.
Kreutz, R. and Stock, P. and Struk, B. and Huebner, N. and Ganten, D. and Lindpaintner, K.
Circulation 96 (4): 1078-1081. 19 August 1997

Actions of angiotensin and lisinopril on thalamic somatosensory neurons in normotensive, non-transgenic and hypertensive, transgenic rats.
Albrecht, D. and Henklein, P. and Ganten, D.
Journal of Hypertension 15 : 1151-1157. 1 January 1997

Antimetaboliten.
Matthes, E. and Langen, P.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 266-301. 1 January 1997

Brain angiotensins in the cardiovascular regulation: usefulness of transgenic animals.
Bricca, G. and Schinke, M. and Boehm, M. and Monti, J. and Hof, H. and Ganten, D. and Bader, M.
Fundamental & Clinical Pharmacology 11, Suppl.1 : 53s-57s. 1 January 1997

Cardiac angiotensin II receptors: studies on functional coupling in Sprague Dawley rats and TGR(aMHC-hAT1) transgenic rats.
Rosenkranz, S. and Nickenig, G. and Flesch, M. and Cremers, B. and Schnabel, P. and Lenz, O. and Krause, T. and Ganten, D. and Hoffmann, S. and Boehm, M.
European Journal of Pharmacology - Molecular Pharmacology Section 330 : 35-46. 1 January 1997

Chronic estrogen treatment in female transgenic (mRen2)27 hypertensive rats augments endothelium-derived nitric oxide release.
Li, P. and Ferrario, C.M. and Ganten, D. and Brosnihan, K.B.
American Journal of Hypertension 10 : 662-670. 1 January 1997

Die Ethikkommission im Universitaetstsklinikum Benjamin Franklin.
Ganten, D. and Koellwitz, A.A.
Magazin fuer Pflegepersonal am Universitaetsklinikum Benjamin Franklin 25 : 9-10. 1 January 1997

Dose effects of human renin in rats transgenic for human angiotensiogen.
Bohlender, J. and Menard, J. and Luft, F.C. and Ganten, D.
Hypertension 291 : 1031-1038. 1 January 1997

Enalapril and pressure-diuresis in hypertensive rats transgenic for mouse renin gene.
Springate, J. and Vanliew, J. and Ganten, D.
Kidney and Blood Pressure Research 20 : 1-5. 1 January 1997

Endothelial injury in transgenic (mRen-2)27 hypertensive rats.
Strawn, W.B. and Gallagher, P. and Dean, R.H. and Ganten, D. and Ferrario, C.M.
American Journal of Hypertension 10 : 51-57. 1 January 1997

Endothelial vasoconstrictor of prostanoids modulate contractions to acetylcholine and ANG II in REN-2 rats.
Noll, G. and Lang, M. and Tschudi, M.R. and Ganten, D. and Luescher, T.F.
American Journal of Physiology Heart and Circulatory Physiology 272 : H493-H500. 1 January 1997

Enzym- und Proteinanalytik.
Westermann, P.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 109-144. 1 January 1997

Genomanalyse und Gendiagnostik.
Hanke, J. and Solinas-Toldo, S. and Hoheisel, J.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 51-91. 1 January 1997

Grundlagen der molekularen Zellbiologie.
Bader, M.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 3-50. 1 January 1997

High human renin hypertension in transgenic rats.
Bohlender, J. and Fukamizu, A. and Lippoldt, A. and Nomura, T. and Dietz, R. and Menard, J. and Murakami, K. and Luft, F.C. and Ganten, D.
Hypertension 29 (1 Pt 2): 428-434. 1 January 1997

High levels of human chymase expression in the pineal and pituitary glands.
Baltatu, O. and Nishimura, H. and Hoffmann, S. and Stoltenburg, G. and Haulica, I.D. and Lippoldt, A. and Ganten, D. and Urata, H.
Brain Research 752 : 269-278. 1 January 1997

Hypertonie.
Ganten, D. and Bohlender, J.
In: Herz-Kreislaufforschung in Deutschland. Kohlhammer, Stuttgart, Berlin, Koeln, 177-185. 1 January 1997

Hypothalamic substance P release: attenuated angiotensin responses in mRen2(27) transgenic rats.
Diz, D.I. and Falgui, B. and Bosch, S.M. and Westwood, B. and Kent, J. and Ganten, D. and Ferrario, C.M.
Hypertension 29 : 510-513. 1 January 1997

Increased potency of neuropeptide y to antagonize alpha2- adrenoceptor function in the nucleus tractus solitarii of the spontaneously hypertensive rat.
Yang, S.N. and Fior, D.R. and Hansson, A. and Cintra, A. and Castellano, M. and Ganten, U. and Ganten, D. and Agnati, L.F. and Fuxe, K.
Neuroscience 78 : 803-813. 1 January 1997

Inhibition of brain renin-angiotensin-system by triple-helix-forming oligonucleotides is associated with modulation of blood pressure power spectrum in rats.
Monti, J. and Voss, A. and Schinke, M. and Boehm, M. and Hoff, H. and Bader, M. and Ganten, D. and Bricca, G.
Fundamental & Clinical Pharmacology 11 Suppl. 1 : S116. 1 January 1997

James D. Watson at the Congress of Molecular Medicine.
Ganten, D.
Journal of Molecular Medicine 75 : 615-617. 1 January 1997

Localization of angiotensin II AT1 receptor like immunoreactivity in catecholaminergic neurons of the rat medulla oblongata.
Yang, S.N. and Lippoldt, A. and Jansson, A. and Phillips, M.I. and Ganten, D. and Fuxe, K.
Neuroscience 81 : 503-515. 1 January 1997

Molekular- und zellbiologische Grundlagen.
Ganten, D and Ruckpaul, K, eds.
Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.]. ISBN 3-540-61954-2 1 January 1997

Praktische Umsetzung des Gentechnikrechts in der Forschung.
Moehring, R.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 389-413. 1 January 1997

Progression of renal failure after subtotal nephrectomy in transgenic rats carrying an additional renin gene [TGR(mREN2)27].
Wagner, J. and Klotz, S. and Haufe, C.C. and Danser, J.A.H. and Amann, K. and Ganten, D. and Ritz, E.
Journal of Hypertension 15 : 441-449. 1 January 1997

Renovascular hypertension with low-to-normal plasma renin: clinical and angiographic features.
Rossi, G.P. and Pavan, E. and Chiesura-Corona, M. and Bader, M. and Paganini, G. and Cesari, M. and De Toni, R. and Feltrin, G.P. and Ganten, D. and Pessina, A.C.
Clinical Science 93 : 435-443. 1 January 1997

Role of the alpha, beta, and gamma subunits of epithelial sodium channel in a model of polygenic hypertension.
Kreutz, R. and Struk, S. and Rubattu, S. and Huebner, N. and Szpirer, J. and Szpirer, C. and Ganten, D. and Lindpaintner, K.
Hypertension 29 : 131-136. 1 January 1997

The stroke-prone spontaneously hypertensive rat and its role in the genetic dissection of cardiovascular disease.
Huebner, N. and Lee, Y.A. and Kreutz, R. and Lindpaintner, K. and Ganten, D.
In: Nutrition and Stroke. Nestle Nutrition Workshop Series, Supplement . Nestec Ltd., Vevey/Lippincott-Raven Publ., Philadelphia, 87-99. 1 January 1997

Tiermodelle in der biomedizinischen Forschung.
Birchmeier, C. and Bladt, F. and Britsch, S.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 338-358. 1 January 1997

Wir brauchen Frische im Geist, Ideen und wirkliches Wollen.
Ganten, D.
Biospektrum 5 : 17-18. 1 January 1997

Worse than pulp fiction: fraud in science.
Ganten, D.
Journal of Molecular Medicine 75 : 689-691. 1 January 1997

1996

Contribution of local renin angiotensin system to cardiac hypertrophy, phenotypic modulation, and remodeling in TGR(mRen2)27 transgenic rats.
Ohta, K. and Kim, S.K. and Wanibuchi, H. and Ganten, D. and Iwao, H.
Circulation 94 (4): 785-791. 15 August 1996

Association and cosegregation of stroke with impaired edothelium-dependent vasorelaxation in stroke prone, spontaneously hypertensive rats.
Volpe, M. and Iaccarino, G. and Vecchione, C. and Rizzoni, D. and Russo, R. and Rubattu, S. and Condorelli, G. and Ganten, U. and Ganten, D. and Trimarco, B. and Lindpaintner, K.
Journal of Clinical Investigation 98 (2): 256-261. 15 July 1996

Chymase- dependent angiotensin II forming system in humans.
Urata, H. and Nishimura, H. and Ganten, D.
American Journal of Hypertension 9 (3): 277-284. 1 March 1996

Demonstration of renin mRNA, angiotensinogen mRNA, and angiotensin converting enzyme mRNA expression in the human eye: evidence for an intraocular renin- angiotensin system.
Wagner, J. and Danser, A.H.J. and Derkx, F.H.M. and Dejong, P.T.V.M. and Paul, M. and Mullins, J.J. and Schalekamp, M.A.D.H. and Ganten, D.
British Journal of Ophthalmology 80 (2): 159-163. 1 February 1996

10 years WHL: from its foundation to the world conference on hypertension control: welcome speech.
Ganten, D.
Journal of Human Hypertension 10 Suppl. : U12-U13. 1 January 1996

Angiotensin I converting enzyme and chymase in cardiovascular tissues.
Nishimura, H. and Hoffmann, S. and Baltatu, O. and Sugimura, K. and Ganten, D. and Urata, H.
Kidney International 49,Suppl.55 : S18-S23. 1 January 1996

Angiotensin-converting enzyme-independent pathways of angiotensin II formation in human tissues and cardiovascular diseases.
Urata, H. and Nishimura, H. and Ganten, D. and Arakawa, K.
Blood Pressure 5, Suppl.2 : 22-28. 1 January 1996

Angiotensinogen gene M235T polymorphism is not associated with diabetic nephropathy.
Schmidt, S. and Giessel, R. and Bergis, K.H. and Strojek, K. and Grzeszcak, W. and Ganten, D. and Ritz, E. and Willms, B.H.L. and Petzold, R. and Henrichs, H.R. and Rambausek, M. and Schwarzbek, A. and Schneider, P. and Bosch, A.
Nephrology Dialysis Transplantation 11 : 1755-1761. 1 January 1996

Angiotensinogen messenger RNA stabilization by angiotensin II.
Klett, C. and Printz, M.P. and Bader, M. and Ganten, D. and Eggena, P.
Journal of Hypertension 14, Suppl.4 : S25-S36. 1 January 1996

Basic fibroblast growth factor expression and tenascin C immunoreactivity after partial unilateral hemitransection of the rat brain.
Lippoldt, A. and Andbjer, B. and Gerst, H. and Ganten, D. and Fuxe, K.
Brain Research 730 : 1-16. 1 January 1996

Cardiorenal consequences of dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibition in transgenic rats with an extra renin gene.
Wegner, M. and Hirth-Dietrich, C. and Knorr, A. and Dressel, J. and Ganten, D. and Stasch, J.P.
Hypertension Research 19 : 151-159. 1 January 1996

Chromosomal mapping of quantitative trait loci contributing to stroke in a rat model of complex human disease.
Rubattu, S. and Volpe, M. and Kreutz, R. and Ganten, U. and Ganten, D. and Lindpaintner, K.
Nature Genetics 13 : 429-434. 1 January 1996

Development, genotype and phenotype of a new colony of the Sabra hypertension prone (SBH/y) and resistant (SBN/y) rat model of salt sensitivity and resistance.
Yagil, C. and Katni, G. and Rubattu, S. and Stolpe, C. and Kreutz, R. and Lindpaintner, K. and Ganten, D. and Ben-Ishay, D. and Yagil, Y.
Journal of Hypertension 14 : 1175-1182. 1 January 1996

Developpement chez le rat d'hypertension a la renine humaine [Development of a model of human renin-dependent hypertension in the rat].
Bohlender, J. and Menard, J. and Wagner, J. and Luft, F.C. and Ganten, D.
Archives des Maladies du Coeur et des Vaisseaux 89 : 1009-1011. 1 January 1996

Effect of losartan on right ventricular hypertrophy and cardiac angiotensin I-converting enzyme activity in pulmonary hypertensive rats.
Kreutz, R. and Fernandez-Alfonso, M.S. and Ganten, D. and Paul, M.
Clinical and Experimental Hypertension 18 (1): 101-111. 1 January 1996

Expression of cytochrome P45011B1 mRNA in the brain of normal and hypertensive transgenic rats.
Erdmann, B. and Gerst, H. and Lippoldt, A. and Buelow, H. and Ganten, D. and Fuxe, K. and Bernhardt, R.
Brain Research 733 : 73-82. 1 January 1996

Human renin-dependent hypertension in rats transgenic for human angiotensinogen.
Bohlender, J. and Menard, J. and Wagner, J. and Luft, F.C. and Ganten, D.
Hypertension 27 : 535-540. 1 January 1996

Hypertension Control: Worldwide Experience. Proceedings of the World Conference on Hypertension Control, Ottawa, Canada, 21 - 24 June, 1995.
Chockalingam, A. and Fodor, J.G. and Ganten, D. and Strasser, T.
Journal of Human Hypertension, Vol. 10, Suppl. 1 . UNSPECIFIED. 1 January 1996

Hypertension control in the world: an agenda for the coming decade (the 1995 WHL Ottawa Declaration).
Sleight, P. and Ganten, D. and Chockalingam, A. and Dodu, S. and Fodor, G. and Froehlich, E. and Lenfant, C. and Moser, M. and Mulrow, P. and Reddy, S. and Ribeiro, A. and Strasser, T.
Journal of Human Hypertension 10 Suppl. : S1-S3. 1 January 1996

Mechanismus der Gewebe-Angiotensin-II-Bildung im Herzen und neue Befunde zum kardialen Angiotensin-II-System.
Urata, H. and Hoffmann, S. and Nishimura, H. and Baltatu, O. and Strobel, F. and Krause, T. and Ganten, D.
In: Angiotensin II - Antagonismus. Ein neuer Weg zur Hochdruckbehandlung. Springer, Berlin, 30-55. 1 January 1996

Molecular cloning and functional characterization of a mouse bradykinin B1 receptor gene.
Pesquero, J.B. and Pesquero, J.L. and Oliveira, S.M. and Roscher, A.A. and Metzger, R. and Ganten, D. and Bader, M.
Biochemical and Biophysical Research Communications 220 (1): 219-225. 1 January 1996

Molecular regulation of smooth muscle contraction.
Morano, I.
In: Molecular Reviews in Cardiovascular Medicine. Chapman & Hall, London [u.a.], 49-53. 1 January 1996

Molekulare Medizin: Herausforderung fuer die Klinische Pharmakologie (Editorial).
Ganten, D.
Biospektrum 2 : 4. 1 January 1996

Neutral endopeptidase inhibition potentiates the effects of natriuretic peptides in renin transgenic rats.
Wegner, M. and Ganten, D. and Stasch, J.P.
Hypertension Research 19 : 229-238. 1 January 1996

Permanent inhibition of angiotensinogen synthesis by antisense RNA expression.
Schinke, M. and Boehm, M. and Bricca, G. and Ganten, D. and Bader, M.
Hypertension 27 : 508-513. 1 January 1996

Physiological characterization of the hypertensive transgenic rat TGR(mREN2)27.
Lee, M.A. and Boehm, M. and Paul, M. and Bader, M. and Ganten, U. and Ganten, D.
American Journal of Physiology Endocrinology and Metabolism 270 : E919-E929. 1 January 1996

Programme for countering emerging infectious diseases (ProCEID) by prophylatic, diagnostic and therapeutic measures. Mission statement, revised.
Geissler, E. and Ganten, D.
Biologicals 24 : 71-74. 1 January 1996

Reduction of cardiac hypertrophy in TGR(mREN2)27 by angiotensin II receptor blockade.
Boehm, M. and Lippoldt, A. and Wienen, W. and Ganten, D. and Bader, M.
Molecular and Cellular Biochemistry 163-164 : 217-221. 1 January 1996

Renal and antihypertensive effects of neutral endopeptidase inhibition in transgenic rats with an extra renin gene.
Stasch, J.P. and Hirth-Dietrich, C. and Ganten, D. and Wegner, M.
American Journal of Hypertension 9 : 795-802. 1 January 1996

Role of area postrema in transgene hypertension.
Averill, D. and Matsumura, K. and Ganten, D. and Ferrario, C.M.
Hypertension 27 : 591-597. 1 January 1996

Role of paraventricular angiotensin AT-1 receptors in salt sensitive hypertension in mRen-2 transgenic rats.
Li, P. and Morris, M. and Diz, D.I. and Ferrario, C.M. and Ganten, D. and Callahan, M.F.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 39 : R1178-R1181. 1 January 1996

Salt sensitive hypertension in (mREN-2)27 transgenic rats.
Callahan, M.F. and Ping, L. and Ferrario, C.M. and Ganten, D. and Morris, M.
Hypertension 27 : 573-577. 1 January 1996

Subcellular localization of angiotensin II immunoreactivity in the rat cerebellar cortex.
Erdmann, B. and Fuxe, K. and Ganten, D.
Hypertension 28 : 818-824. 1 January 1996

Synthesis and secretion of natriuretic peptides in the hypertensive TGR(mREN-2)27 transgenic rat.
Marttila, M. and Vuolteenaho, O. and Ganten, D. and Nakao, K. and Ruskoaho, H.
Hypertension 28 : 995-1004. 1 January 1996

The hypertensive Ren-2 transgenic rat TGR(mREN2)27 in hypertension research characteristics and functional aspects.
Langheinrich, M. and Lee, M.A. and Boehm, M. and Pinto, Y.M. and Ganten, D.
American Journal of Hypertension 9 (5): 506-512. 1 January 1996

The renin-angiotensin system and renal function in transgenic (mRen2)27 rats.
Gross, V. and Lippoldt, A. and Bohlender, J. and Ganten, D. and Ganten, U. and Luft, F.C.
Experimental Nephrology 4, Suppl.1 : 20-26. 1 January 1996

The renin-angiotensin system in transgenic rats.
Wagner, J. and Thiele, F. and Ganten, D.
Pediatric Nephrology 10 (1): 108-112. 1 January 1996

Transcriptional regulatory elements in the rat bradykinin B2 receptor gene.
Pesquero, J.B. and Lindsey, C.J. and Paiva, A.C.M. and Ganten, D. and Bader, M.
Immunopharmacology 33 : 36-41. 1 January 1996

Transgenic rats: tools to study the function of the renin-angiotensin system. Proceedings of the symposium 'angiotensin AT1 receptors: from molecular physiology to therapeutics'.
Bader, M. and Ganten, D.
Clinical and Experimental Pharmacology and Physiology Suppl.3 : S81-S87. 1 January 1996

Was kann die Medizin von der Gentechnik erwarten?
Ganten, D.
In: Wissenschaftszentrum Nordrhein-Westfalen: Jahrbuch 1995. Wissenschaftszentrum Nordrhein-Westfalen, Duesseldorf, 80-89. 1 January 1996

Molecular reviews in cardiovascular medicine.
Lindpaintner, K. and Ganten, D.
Springer, Berlin. ISBN 0-412-78260-X 1996

1995

Liposomaler Gentransfer in Nierenzellen.
Madry, H.
UNSPECIFIED thesis, UNSPECIFIED. 20 December 1995

Genetic linkage of the ACE gene to plasma angiotensin-converting enzyme activity but not to blood pressure: a quantitative trait locus confers identical complex phenotypes in human and rat hypertension.
Kreutz, R. and Huebner, N. and Ganten, D. and Lindpaintner, K.
Circulation 92 (9): 2381-2384. 1 November 1995

No association of converting enzyme insertion/deletion polymorphism with immunoglobulin a glomerulonephritis.
Schmidt, S. and Stier, E. and Hartung, R. and Stein, G. and Bahnisch, J. and Woodroffe, A.J. and Clarkson, A.R. and Ponticelli, C. and Campise, M. and Mayer, G. and Ganten, D. and Ritz, E.
American Journal of Kidney Diseases 26 (5): 727-731. 1 November 1995

Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10.
Kreutz, R. and Huebner, N. and James, M.R. and Bihoreau, M.T. and Gauguier, D. and Lathrop, G.M. and Ganten, D. and Lindpaintner, K.
Proceedings of the National Academy of Sciences of the United States of America 92 (19): 8778-8782. 12 September 1995

Regulation of aldosterone biosynthesis by adrenal renin is mediated through AT1 receptors in renin transgenic rats.
Volpe, M. and Rubattu, S. and Gigante, G. and Ganten, D. and Porcellini, A. and Russo, R. and Romano, M. and Enea, I. and Lee, M.A. and Trimarco, B.
Circulation Research 77 (1): 73-79. July 1995

Opposing actions of angiotensin-(1-7) and angiotensin II in the brain of transgenic hypertensive rats.
Moriguchi, A. and Tallant, E.A. and Matsumura, K. and Reilly, T.M. and Walton, H. and Ganten, D. and Ferrario, C.M.
Hypertension 25 (6): 1260-1265. 1 June 1995

Angiotensin and bradykinin peptides in the TGR(mREN-2)27 rat.
Campbell, D.J. and Rong, P. and Kladis, A. and Rees, B. and Ganten, D. and Skinner, S.L.
Hypertension 25 (5): 1014-1020. 1 May 1995

Alterations of cardiac alpha- and beta-adrenoceptors and inotropic responsiveness in hypertensive transgenic rats harbouring the mouse renin gene (TGR(mREN2)27).
Tawfik-Schlieper, H. and Moll, M. and Schmid, B. and Schwinger, R.H.G. and Paul, M. and Ganten, D. and Boehm, M.
Clinical and Experimental Hypertension 17 : 631-648. 1 January 1995

Altered angiotensinogen amino acid sequence and plasma angiotensin II levels in genetically hypertensive rats: a study on cause and effects.
Huebner, N. and Kreutz, R. and Takahashi, S. and Ganten, D. and Lindpaintner, K.
Hypertension 26 : 279-284. 1 January 1995

Angiotensin II receptor blockade in TGR(mREN2)27: effects of renin-angiotensin-system gene expression and cardiovascular functions.
Boehm, M. and Lee, M.A. and Kreutz, R. and Kim, S. and Schinke, M. and Djavidani, B. and Wagner, J. and Kaling, M. and Wienen, W. and Bader, M. and Ganten, D.
Journal of Hypertension 13 : 891-899. 1 January 1995

Auf dem Wege zu verbesserter klinischer Forschung.
Ganten, D. and Schnitzer-Ungefug, J.
In: Community Medicine. 1.Internationaler Workshop in Greifswald. Peter Lang, Frankfurt /Main, 169-183. ISBN 3-631-48080-6 1 January 1995

Charakterisierung der transgenen Rattenlinie TGR(mREN2)27.
Lee, M.A.
UNSPECIFIED thesis, UNSPECIFIED. 1 January 1995

Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27.
Djavidani, B. and Sander, M. and Kreutz, R. and Zeh, K. and Bader, M. and Mellon, S.H. and Vecsei, P. and Peters, J. and Ganten, D.
Journal of Hypertension 13 (6): 637-645. 1 January 1995

Contribution of A 12 kDa protein to the angiotensin II-induced stabilization of angiotensinogen mRNA : interaction with the 3'untranslated mRNA.
Klett, C. and Bader, M. and Schwemmle, M. and Ganten, D. and Hackenthal, E.
Journal of Molecular Endocrinology 14 : 209-226. 1 January 1995

Converting enzyme inhibitors differentially affect expression of genes of the renin-angiotensin system.
Keuneke, C. and Yacullo, R. and Sugiura, M. and Mall, G. and Metzger, R. and Ganten, D.
Clinical and Experimental Hypertension 17 (3): 551-574. 1 January 1995

Decreased renal haemodynamic response to inhibition of nitric oxide synthase in subtotally nephrectomised rats.
Wagner, J. and Wystrychowski, A. and Stauss, H. and Ganten, D. and Ritz, E.
Pfluegers Archiv European Journal of Physiology 430 : 181-187. 1 January 1995

Diagnostik und Therapie des Bluthochdrucks.
Ganten, D.
MED-REPORT 18 (27): 4-4. 1 January 1995

Die Genetik der Hypertonie.
Ganten, D. and Stolpe, C. and Lindpaintner, K.
In: Berlin-Brandenburgische Akademie der Wissenschaften : Jahrbuch 1994. Akad.Verl., Berlin, 223-231. ISBN 3-05-002774-6 1 January 1995

Die Genetik des Bluthochdrucks: Molekulare Analyse einer Volkskrankheit.
Ganten, D. and Stolpe, C. and Lindpaintner, K.
In: Wissenschaft in der globalen Herausforderung. Verhandlungen der Gesellschaft Deutscher Naturforscher und Ärzte 118.Versammlung - Hamburg 1994. Wiss.Verlagsgesellschft mbH, Stuttgart, 351-364. 1 January 1995

Differential gene expression of renin and angiotensinogen in the TGR(mREN-2)27 transgenic rat.
Lee, M.A. and Boehm, M. and Kim, S. and Bachmann, S. and Bachmann, J. and Bader, M. and Ganten, D.
Hypertension 25 : 570-580. 1 January 1995

Effects of human renin in the vasculature of rats transgenic for human angiotensinogen.
Mueller, D.N. and Hilgers, K.F. and Bohlender, J. and Lippoldt, A. and Wagner, J. and Fischli, W. and Ganten, D. and Mann, J.F.E. and Luft, F.C.
Hypertension 26 : 272-278. 1 January 1995

Endothelin and experimental hypertension.
Boecker, W. and Ganten, D. and Paul, M.
In: Experimental Hypertension and Therapeutic Progress: Vasodilation and Beyond. Springer, Berlin [u.a.], 1-14. ISBN 3-540-58545-1 1 January 1995

Evidence for a differential modulation of the alpha-2 adrenoreceptors by angiotensin II in the nucleus tractus solitarii of the spontaneously hypertensive and the wistar kyoto normotensive rats.
Fior, D.R. and Yang, S.N. and Ganten, U. and Ganten, D. and Fuxe, K.
Brain Research 679 : 168-177. 1 January 1995

Expression of the mouse and rat mas proto-oncogene in the brain and peripheral tissues.
Metzger, R. and Bader, M. and Ludwig, T. and Berberich, C. and Bunnemann, B. and Ganten, D.
FEBS Letters 357 : 27-32. 1 January 1995

Gene expression of brain nitric oxide synthase and soluble guanylyl cyclase in hypothalamus and medulla of two-kidney, one clip hypertensive rats.
Krukoff, T.L. and Gehlen, F. and Ganten, D. and Wagner, J.
Hypertension 26 : 171-176. 1 January 1995

Genetics in arterial hypertension - clinical and experimental aspects.
Huebner, N. and Ganten, D.
Herz 20 : 309-314. 1 January 1995

Genetics of hypertension.
Lindpaintner, K. and Kreutz, R. and Ganten, D.
In: Scientific American: Molecular Cardiovascular Medicine. Scientific American Inc., New York, 243-257. 1 January 1995

Genetische Analyse des Bluthochdrucks.
Lee, Y.A. and Huebner, N. and Ganten, D.
In: Jahrbuch 1995 der Deutschen Akademie der Naturforscher Leopoldina (Halle/Saale). Leopoldina, R.3, 41 . Dt. Akad. d. Naturforscher Leopoldina, Halle/Saale, 323-333. 1 January 1995

Hormones, autacoids, neurotransmitters, and growth factors.
Ganten, D. and Luft, F.C. and Kurokawa, K.
Current Opinion in Nephrology and Hypertension 4 : B1-B18. 1 January 1995

Increased vasopressor actions of intraventricular neuropeptide Y-(13-36) in spontaneously hypertensive versus normotensive Wistar-Kyoto rats. Possible relationship to increases in Y2 receptor binding in the nucleus tractus solitarius.
Aguirre, J.A. and Hedlund, P.B. and Narvaez, J.A. and Bunnemann, B. and Ganten, D. and Fuxe, K.
Brain Research 684 (2): 159-164. 1 January 1995

Induction of cardiac angiotensin I-converting enzyme with dietary NaCL-loading in genetically hypertensive and normotensive rats.
Kreutz, R. and Fernandez-Alfonso, M.S. and Liu, Y. and Ganten, D. and Paul, M.
Journal of Molecular Medicine 73 (5): 243-248. 1 January 1995

Infertility in a transgenic rat due to impairment of cytoplasmic elimination and sperm release from the sertoli cells.
Sharpe, R.M. and Maguire, S.M. and Saunders, P.T.K. and Millar, M.R. and Russel, L.D. and Ganten, D. and Bachmann, S. and Mullins, L. and Mullins, J.J.
Biology of Reproduction 53 : 214-226. 1 January 1995

Local renin-angiotensin systems in cardiovascular tissues: localization and functional role.
Stock, P. and Liefeld, L. and Paul, M. and Ganten, D.
Cardiology 86 (Suppl.1): 2-8. 1 January 1995

Mechanisms of angiotensin II formation in humans.
Urata, H. and Nishimura, H. and Ganten, D.
European Heart Journal 16, Suppl.N : 79-85. 1 January 1995

Molecular structure of rat bradykinin B2 receptor gene.
Pesquero, J.B. and Lindsey, C.J. and Zeh, K. and Paiva, A.C.M. and Ganten, D. and Bader, M.
Nieren- und Hochdruckkrankheiten 24 : 602-604. 1 January 1995

Neurotransmitters and neuropeptides in the baroreceptor reflex arc: connections between the nucleus of the solitary tract and the ventrolateral medulla oblongata in the rat.
Palkovits, M. and Mezey, E. and Fodor, M. and Ganten, D. and Bahner, U. and Geiger, H. and Heidland, A.
Clinical and Experimental Hypertension 17 : 101-113. 1 January 1995

Novel approaches towards the nuclear expression of ribozyme and antisense RNA genes in transgenic mice.
Sharp, M.G.F. and Ganten, D. and Mullins, J.J.
In: Mechanisms and Applications of Gene Silencing. University Press, Nottingham, 185-194. 1 January 1995

Rodent models for studying steroids and hypertension : from fetal development to cells in culture.
Mellon, S.H. and Compagnone, N. and Sander, M. and Cover, C. and Ganten, D. and Djavidani, B.
Steroids 60 (1): 59-64. 1 January 1995

The brain renin-angiotensin system: molecular mechanisms of cell to cell interactions.
Lippoldt, A. and Paul, M. and Fuxe, K. and Ganten, D.
Clinical and Experimental Hypertension 17 : 251-266. 1 January 1995

The gene encoding endothelial nitric oxide synthase, Nos3, maps to rat chromosome 4.
Huebner, N. and Kreutz, R. and Rubattu, S. and Lee, Y.A. and Ganten, D. and Allen, P.D. and Lindpaintner, K.
Mammalian Genome 6 (10): 758-759. 1 January 1995

The world hypertension league: goals and perspectives.
Ganten, D. and Poetzsch, J.
Clinical and Experimental Hypertension 17 (7): 1079-1089. 1 January 1995

Tradition, continuity, and renaissance.
Ganten, D.
Journal of Molecular Medicine 73 : 1-3. 1 January 1995

Transcriptional silencer in intron I of the rat renin gene.
Voigtlaender, T. and Ripperger, A. and Ganten, D. and Bader, M.
Advances in Experimental Medicine and Biology 377 : 285-292. 1 January 1995

Transgenic animals as models for human disease (Review).
Wagner, J. and Thiele, F. and Ganten, D.
Clinical and Experimental Hypertension 17 (4): 593-605. 1 January 1995

Transgenic laboratory animals in hypertension research.
van der Giet, M. and Hoffmann, S. and Urata, H. and Ganten, D. and Paul, M.
Scandinavian Journal of Laboratory Animal Sciences 22 (2): 205-211. 1 January 1995

Verbund Klinische Pharmakologie Berlin/Brandenburg. Gentherapie, Pharmakogenetik, Pharmakoepidemiologie.
Ganten, D. and Engler, E. and Ruckpaul, K.
Klinische Pharmakologie aktuell 6 : 44-54. 1 January 1995

Vom Gen zur Therapie: Paradigmenwechsel in der Klinischen Pharmakologie.
Ganten, D.
Klinische Pharmakologie aktuell 6 : 35-36. 1 January 1995

Association of M235T variant of the angiotensinogen gene with familial hypertension of early onset.
Schmidt, S. and Sharma, A.M. and Zilch, O. and Beige, J. and Walla-Friedel, M. and Ganten, D. and Distler, A. and Ritz, E.
Nephrology Dialysis Transplantation 10 (7): 1145-1148. 1995

1994

Widespread tissue distribution of human chymase.
Urata, H. and Strobel, F. and Ganten, D.
Journal of Hypertension 12 (Suppl.) (9): S17-S22. 1 November 1994

Augmented agonist induced Ca2+-sensitization of coronary artery contraction in genetically hypertensive rats - evidence for altered signal transduction in the coronary smooth muscle cells.
Satoh, S. and Kreutz, R. and Wilm, C. and Ganten, D. and Pfitzer, G.
Journal of Clinical Investigation 94 (4): 1397-1403. October 1994

Alteration in coronary artery vascular reactivity of hypertensive Ren-2 transgenic rats.
Tschudi, M.R. and Noll, G. and Arnet, U. and Novosel, D. and Ganten, D. and Luescher, T.F.
Circulation 89 (6): 2780-2786. June 1994

Mechanisms of hypertension in transgenic rats expressing the mouse Ren-2 gene.
Moriguchi, A. and Brosnihan, K.B. and Kumagai, H. and Ganten, D. and Ferrario, C.M.
American Journal of Physiology Renal Physiology 266 (4 Pt 2): R1273-R1279. 1 April 1994

Role of adrenal renin in the regulation of adrenal steroidogenesis corticotropin.
Sander, M. and Ganten, D. and Mellon, S.H.
Proceedings of the National Academy of Sciences of the United States of America 91 (1): 148-152. 4 January 1994

Activation of the renin-angiotensin system in heart failure and hypertrophy - studies in human hearts and transgenic rats.
Paul, M. and Pinto, Y.M. and Schunkert, H. and Ganten, D. and Boehm, M.
European Heart Journal 15 (Suppl.D) : 63-67. 1 January 1994

Basic methods of molecular biology in cardiovascular research.
Paul, M. and Bader, M. and Wagner, J. and Ganten, D.
In: Molecular Cell Biology of Cardiovascular Diseases. Mosby, Madrid [u.a.], 41-48. 1 January 1994

Biesenthal consensus: Biesenthal vaccine initiative (Vaccines for peace).
Calderon, F. and Drozdov, S.G. and Fenner, F. and Ganten, D. and Geissler, E. and Horoud, F. and Kane, M. and L'age-Stehr, J. and Langen, P. and Leitenberg, M. and Melling, J. and Morse, S.S. and Netesov, S.V. and Nixdorff, K. and Pearson, G. and Sandstroem, G. and Subrahmanyam, D. and Thraenert, O. and Toth, T. and Valette, M.L. and Wheelis, M.L. and Woodall, J.P.
In: The Royal Society: Scientific of Control of Biological Weapons. Royal Society Study Group, London, 121-125. 1 January 1994

Bluthochdruck. Die beteiligten Gene und ihre Bedeutung.
Kreutz, R. and Huebner, N. and Ganten, D. and Lindpaintner, K.
In: Wieviel Genetik braucht der Mensch. Konstanzer Bibliothek ; 23 . Univ.-Verl., Konstanz, 239-252. 1 January 1994

Differential regulation of central vasopressin in transgenic rats harboring the mouse Ren-2 gene.
Moriguchi, A. and Ferrario, C.M. and Brosnihan, K.B. and Ganten, D. and Morris, M.
American Journal of Physiology Renal Physiology 267 : R786-R791. 1 January 1994

Differential regulation of vascular angiotensin I-converting enzyme in hypertension.
Fernandez-Alfonso, M.S. and Kreutz, R. and Zeh, K. and Liu, Y. and Ganten, D. and Paul, M.
Hypertension 24 : 280-286. 1 January 1994

Effects of enalaprilat on circadian profiles in blood pressure and heart rate of spontaneously and transgenic hypertensive rats.
Lemmer, B. and Witte, K. and Makabe, T. and Ganten, D. and Mattes, A.
Journal of Cardiovascular Pharmacology 23 : 311-314. 1 January 1994

Effects of nephrectomy and adrenalectomy on the renin-angiotensin system on transgenic rats TGR(mRen2)27.
Tokita, Y. and Franco-Saenz, R. and Mulrow, P.J. and Ganten, D.
Endocrinology 134 : 253-257. 1 January 1994

Enhanced adrenal renin and aldosterone biosynthesis during sodium restriction in TGR (mREN2)27.
Rubattu, S. and Enea, I. and Ganten, D. and Salvatore, D. and Condorelli, G.L. and Condorelli, G. and Russo, R. and Romano, M. and Gigante, B. and Trimarco, B. and Volpe, M.
American Journal of Physiology Endocrinology and Metabolism 267 : E515-E520. 1 January 1994

Estrogen augments the contribution of nitric oxide to blood pressure regulation in transgenic hypertensive rats expressing the mouse Ren-2 gene.
Brosnihan, K.B. and Moriguchi, A. and Nakamoto, H. and Dean, R.H. and Ganten, D. and Ferrario, C.M.
American Journal of Hypertension 7 : 576-582. 1 January 1994

Experimental and genetic models of hypertension.
Ganten, D.
Handbook of Hypertension ; 16 . Elsevier, Amsterdam. 1 January 1994

Genetics of primary hypertension.
Schmidt, S. and Ganten, D.
Nephrology Dialysis Transplantation 9 : 473-474. 1 January 1994

Genetics of primary hypertension.
Ganten, D. and Schmidt, S. and Paul, M.
Journal of Cardiovascular Pharmacology 24 : S45-S50. 1 January 1994

Human angiotensinogen if highly expressed in astrocytes in human cortical grafts.
Humpel, C. and Lippoldt, A. and Stroemberg, I. and Bygdeman, M. and Wagner, J. and Hilgenfeldt, U. and Ganten, D. and Fuxe, K. and Olson, L.
Glia 10 : 186-192. 1 January 1994

Human heart chymase.
Husain, A. and Kinoshita, A. and Sung, S.S. and Urata, H. and Bumpus, F.M.
In: The Cardiac Renin-Angiotensin System. Futura Medical Publ., New York, 309-331. 1 January 1994

Increase of basic fibroblast growth factor (bFGF,FGF-2) messenger RNA and protein following implantation of a microdialysis probe into rat hippocampus.
Humpel, C. and Chadi, G. and Lippoldt, A. and Ganten, D. and Fuxe, K. and Olson, L.
Experimental Brain Research 98 : 229-237. 1 January 1994

Increased cytosolic sodium and reduced Na,K-ATPase activity in transgenic rats.
Tepel, M. and Theilmeier, G. and Bachmann, J. and Barenbrock, M. and Spieker, C. and Ganten, D. and Rahn, K.H. and Zidek, W.
Hypertension 23, Suppl. I : I-198-I-202. 1 January 1994

Insulin resistance and hypertension: studies in transgenic hypertensive TGR(mREN-2)27 rats.
Vetter, R. and Cusin, I. and Ganten, D. and Rohner-Jeanrenaud, F. and Ferrannini, E. and Jeanrenaud, B.
American Journal of Physiology Renal Physiology 267 (6): R1503-R1509. 1 January 1994

Kraft fuer den Aufschwung. Biomedizinische Forschung in den neuen Bundeslaendern.
Ganten, D.
Wissenschaft und Wirtschaft 3 : 38-44. 1 January 1994

Mechanism by which angiotensin II stabilizes messenger RNA for angiotensinogen.
Klett, C. and Bader, M. and Ganten, D. and Hackenthal, E.
Hypertension 23 : I120-I125. 1 January 1994

Molecular biology and biochemistry of the renin-angiotensin system.
Bader, M. and Paul, M. and Fernandez-Alfonso, M.S. and Kaling, M. and Ganten, D.
In: Textbook of Hypertension. Blackwell, Oxford, 214-232. 1 January 1994

Molecular mechanisms of renin expression and regulation: functional relevance for the activity of the renin angiotensin system.
Paul, M. and Ganten, D.
In: Regulation and Control of Complex Biological Processes by Biotransformation. Frontiers in Biotransformation ; 9 . Akademie Verl., Berlin, 1-59. 1 January 1994

Molecular structure and expression of rat bradykinin B2 receptor gene. Evidence for alterative splicing.
Pesquero, J.B. and Lindsey, C.J. and Zeh, K. and Paiva, A.C.M. and Ganten, D. and Bader, M.
Journal of Biological Chemistry 43 : 26920-26925. 1 January 1994

Molekulargenetische Grundlagen und Perspektiven fuer die Diagnostik und Therapie des Bluthochdrucks.
Ganten, D.
Laboratory Medicine 18 : 351-352. 1 January 1994

Neue Strategien zur Praevention und Therapie der Hypertonie (Gespraech anlaesslich des 6th European Meeting on Hypertension, Mailand 4.-7. Juni 1993).
Ganten, D.
Herz Kreislauf 26 : IV-VI. 1 January 1994

On the plasticity of the cerebellar renin-angiotensin system: Localization of components and effects of mechanical perturbation.
Lippoldt, A. and Bunnemann, B. and Ueki, A. and Rosen, L. and Cintra, A. and Hasselrot, U. and Metzger, R. and Hilgenfeldt, U. and Brosnihan, K.B. and Ganten, D. and Fuxe, K.
Brain Research 668 : 144-159. 1 January 1994

PCR analysis of human renal biopsies - renin gene regulation in glomerulonephritis.
Wagner, J. and Drab, M. and Gehlen, F. and Langheinrich, M. and Volk, S. and Ganten, D. and Ritz, E.
Kidney International 46 : 1542-1545. 1 January 1994

Pathophysiologie des Renin-Angiotensin-Systems.
Klett, C. and Paul, M. and Hackenthal, E. and Ganten, D.
In: ACE-Hemmer : Handbuch. 2., ueberarb. und erw. Aufl. Schattauer, Stuttgart [u.a.], 9-74. 1 January 1994

Renal effects of captopril and nitrendipine in transgenic rats with an extra renin gene.
Hirth-Dietrich, C. and Stasch, J.P. and Ganten, D. and Luft, F.C.
Hypertension 23 : 626-631. 1 January 1994

Renal function in hypertensive rats transgenic for mouse renin gene.
Springate, J.E. and Feld, L.G. and Ganten, D.
American Journal of Physiology 266 : F731-F737. 1 January 1994

The Cardiac Renin-Angiotensin System.
Lindpaintner, K. and Ganten, D.
Futura Publ. Comp., Armonk. 1 January 1994

The cardiac renin-angiotensin system and human coronary physiology and pathology.
Osterziel, K.J. and Dietz, R.
In: The Cardiac Renin-Angiotensin System. Futura Publishing Company, Inc., Armonk, NY, 333-343. 1 January 1994

The human renin-angiotensin-system in transgenic rats.
Ganten, D. and Wagner, J.
In: Patenting of Human Genes and Living Organisms. Springer, Berlin, 185-196. 1 January 1994

The role of the renin-angiotensin system in cardiovascular disease.
Bader, M. and Wagner, J. and Lee, M.A. and Ganten, D.
Hypertension Research 17 : 1-16. 1 January 1994

Tissue angiotensin II system in the human heart.
Urata, H. and Hoffmann, S. and Ganten, D.
European Heart Journal 15 (Suppl D): 68-78. 1 January 1994

Transgenic animal models for hypertension.
Paul, M. and Wagner, J. and Bader, M. and Ganten, D.
In: Textbook of Hypertension. Blackwell, Oxford, 469-476. 1 January 1994

Transgenic rats and experimental hypertension.
Hoffmann, S. and Paul, M. and Urata, H. and Wagner, J. and Ganten, D.
In: Hypertension: Pathophysiology, Diagnosis, and Management. Raven Press, New York, [s.p.]. 1 January 1994

Transgenic rats expressing components of the renin-angiotensin system : focus on cardiovascular regulation.
Paul, M. and Wagner, J. and Kreutz, R. and Fernandez-Alfonso, M.S. and Liu, Y. and Bader, M. and Ganten, D.
In: The Cardiac Renin-Angiotensin System. Futura Publ. Comp., Armonk, [s.p.]. 1 January 1994

Unlike human hypertension, blood pressure in a hereditary hypertensive rat strain shows no linkage to the angiotensinogen locus.
Huebner, N. and Kreutz, R. and Takahashi, S. and Ganten, D. and Lindpaintner, K.
Hypertension 23 : 797-801. 1 January 1994

Vascular angiotensin and the sympathetic nervous system: do they interact?
Hilgers, K.F. and Veelken, R. and Kreppner, I. and Ganten, D. and Luft, F.C. and Geiger, H. and Mann, J.F.
American Journal of Physiology Heart and Circulatory Physiology 267 : H187-H194. 1 January 1994

Zona glomerulosa of the adrenal gland in a transgenic strain of rat: A morphologic and functional study.
Rocco, S. and Rebuffat, P. and Cimolato, M. and Opocher, G. and Peters, J. and Mazzocchi, G. and Ganten, D. and Mantero, F. and Nussdorfer, G.G.
Cell and Tissue Research 278 : 21-28. 1 January 1994

beta-adrenergic neuroeffector mechanisms in cardiac hypertrophy of renin transgenic rats.
Boehm, M. and Moll, M. and Schmid, B. and Paul, M. and Ganten, D. and Castellano, M. and Erdmann, E.
Hypertension 24 : 653-662. 1 January 1994

Increased expression of angiotensin peptides in the brain of transgenic hypertensive rats.
Senanayake, P.D. and Moriguchi, A. and Kumagai, H. and Ganten, D. and Ferrario, C.M. and Brosnihan, K.B.
Peptides 15 (5): 919-926. 1994

Transgenic rats: new experimental models for the study of candidate genes in hypertension research.
Paul, M. and Wagner, J. and Hoffmann, S. and Urata, H. and Ganten, D.
Annual Review of Physiology 56 : 811-829. 1994

1993

Antisense oligonucleotide to c-fos induces ipsilateral rotational behaviour to d-amphetamine.
Sommer, W. and Bjelke, B. and Ganten, D. and Fuxe, K.
NeuroReport 5 (3): 277-280. 13 December 1993

The renin-angiotensin system in the brain: an update 1993.
Bunnemann, B. and Fuxe, K. and Ganten, D.
Regulatory Peptides 46 (3): 487-509. 23 July 1993

Circadian blood pressure variation in transgenic hypertensive rats.
Lemmer, B. and Mattes, A. and Boehm, M. and Ganten, D.
Hypertension 22 (1): 97-101. July 1993

Tissue renin-angiotensin systems. Their role in cardiovascular disease.
Lee, M.A. and Boehm, M. and Paul, M. and Ganten, D.
Circulation 87 (Suppl IV): 7-13. May 1993

Increased adrenal renin in transgenic hypertensive rats, TGR(mREN2)27, and its regulation by cAMP, angiotensin II and calcium.
Peters, J. and Muenter, K. and Bader, M. and Hackenthal, E. and Mullins, J.J. and Ganten, D.
Journal of Clinical Investigation 91 (3): 742-747. March 1993

Transgene Ratten, die in ihrem Genom mindestens ein menschliches Gen enthalten, das an der Blutdruckregulation beteiligt ist [Transgenic rats having at least one human gene in their genome, participating in the regulation of the blood-pressure].
Ganten, D. and Mullins, J. and Murakami, K.
EP0528360A2 ; EP0528360A3 ; EP0528360B1. 24 February 1993

Selective activation of cardiac angiotensinogen gene expression in post-infarction ventricular remodeling in the rat.
Lindpaintner, K. and Lu, W. and Niedermaier, N. and Schieffer, B. and Just, H. and Ganten, D. and Drexler, H.
Journal of Molecular and Cellular Cardiology 25 (2): 133-143. February 1993

Androgene regulieren die Transkriptionsrate der schweren alpha -Myosinkette im Herzen.
Kaling, M. and Morano, I.
In: Zellulaere Mechanismen der Herz-Kreislaufregulation. Pharmakologische und klinische Konsequenzen. Franz Gross Hypertonie Symposium, Schlosshotel Kronberg, 5.-7.Maerz 1992 . Schattauer, Stuttgart, 151-158. 1 January 1993

Angiotensinogen is cleaved to angiotensin in isolated rat blood vessels.
Hilgers, K.F. and Hilgenfeldt, U. and Veelken, R. and Muley, T. and Ganten, D. and Luft, F.C. and Mann, J.F.
Hypertension 21 : 1030-1034. 1 January 1993

Angiotensinogen mRNA and pressor reactions to angiotensin in brain stem areas of spontaneously hypertensive rats.
Chai, C.Y. and Hellmann, W. and Tseng, C.J. and Luft, F.C. and Ganten, D.
Clinical and Experimental Hypertension 15 : 709-725. 1 January 1993

Biesenthal consensus: Biesenthal vaccine initiative (Vaccines for peace).
Calderon, F. and Drozdov, S.G. and Fenner, F. and Ganten, D. and Geissler, E. and Horoud, F. and Kane, M. and L'age-Stehr, J. and Langen, P. and Leitenberg, M. and Melling, J. and Morse, S.S. and Netesov, S.V. and Nixdorff, K. and Pearson, G. and Sandstroem, G. and Subrahmanyam, D. and Thraenert, O. and Toth, T. and Valette, M.L. and Wheelis, M.L. and Woodall, J.P.
Politics and the Life Sciences 12 : 101-103. 1 January 1993

Cardiac angiotensin-II formation: the angiotensin-I converting- enzyme and human chymase.
Urata, H. and Ganten, D.
European Heart Journal 14 : 177-182. 1 January 1993

Cellular expression of angiotensin type-1 receptor mRNA in the kidney.
Meister, B. and Lippoldt, A. and Bunnemann, B. and Inagami, T. and Ganten, D. and Fuxe, K.
Kidney International 44 : 331-33. 1 January 1993

Cellular localization of angiotensin type 1 receptor and angiotensinogen mRNAs in the subfornical organ of the rat brain.
Lippoldt, A. and Bunnemann, B. and Metzger, R. and Fuxe, K. and Ganten, D.
Neuroscience Letters 150 : 153-158. 1 January 1993

Dietary salt excess unmasks blunted aldosterone suppression and sodium retention in stroke-prone phenotype of the spontaneously hypertensive rat.
Volpe, M. and Rubattu, S. and Ganten, D. and Enea, I. and Russo, R. and Lembo, G. and Mirante, A. and Condorelli, G. and Trimarco, B.
Journal of Hypertension 11 : 793-798. 1 January 1993

Expression of the mouse ren-2 gene in the small intestine is regulated by food intake.
Zhao, Y. and Peters, J. and Ganten, D. and Bader, M.
Pfluegers Archiv European Journal of Physiology 424 : 199-202. 1 January 1993

Extra-hepatic transcription of plasma prekallikrein gene in human and rat tissues.
Ciechanowicz, A. and Bader, M. and Wagner, J. and Ganten, D.
Biochemical and Biophysical Research Communications 197 : 1370-1376. 1 January 1993

Fast and widespread increase of basic fibroblast growth factor messenger RNA and protein in the forebrain after kainate-induced seizures.
Humpel, C. and Lippoldt, A. and Chadi, G. and Ganten, D. and Olson, L. and Fuxe, K.
Neuroscience 57 : 913-922. 1 January 1993

Festschrift anlaesslich der Gruendung des Max-Delbrueck-Centrum fuer Molekulare Medizin in Berlin-Buch. Symposium: "Wissenschaftsgeschichte und Molekulare Medizin in Berlin-Buch".
Bielka, H. and Ganten, D.
Max-Delbrueck-Centrum fuer Molekulare Medizin, Berlin-Buch. 1 January 1993

Gap junction protein connexin40 is preferentially expressed in vascular endothelium and conductive bundles of rat myocardium and is increased under hypertensive conditions.
Bastide, B. and Neyses, L. and Ganten, D. and Paul, M. and Willecke, K. and Traub, O.
Circulation Research 73 : 1138-1149. 1 January 1993

Gene regulation of beta-1-adrenergic receptor in genetically hypertensive rats.
Castellano, M. and Paul, M. and Beschi, M. and Bachmann, J. and Rizzoni, D. and Porteri, E. and Bettoni, G. and Cinelli, A. and Ganten, D. and Agabiti-Rosei, E.
Journal of Hypertension 11 (Suppl.) : S64-S65. 1 January 1993

High blood pressure maintenance in transgenic mRen-2 vs. Lyon genetically hypertensive rats.
Lo, M. and Medeiros, I.A. and Mullins, J.J. and Ganten, D. and Barres, C. and Cerutti, C. and Vincent, M. and Sassard, J.
American Journal of Physiology Renal Physiology 265 : R180-R186. 1 January 1993

Hormones, autacoids, neurotransmitters, and growth factors.
Ganten, D. and Luft, F.C. and Kurokawa, K.
Current Opinion in Nephrology and Hypertension 2 : 1-4. 1 January 1993

Hypertension summer school 1992.
Ganten, D.
Clinical and Experimental Hypertension 15 : 617-618. 1 January 1993

Immobilization stress induces vasodepressor and altered neuroendocrine responses in the adult stroke-prone, spontaneously hypertensive male rat.
Narvaez, J.A. and Aguirre, J.A. and Haerfstrand, A. and Eneroth, P. and Ganten, D. and Agnati, L.F. and Fuxe, K.
Acta Physiologica Scandinavica 149 : 491-501. 1 January 1993

Investigating the genetics of hypertension.
Bader, M. and Paul, M. and Ganten, D.
ACE Report 99 : 6-10. 1 January 1993

Isolierte systolische Hypertonie im Alter.
Staessen, J. and Ritz, E. and Faulhaber, H.D. and Gellert, J. and Ganten, D. and Amery, A.
Deutsche Medizinische Wochenschrift 118 : 554-560. 1 January 1993

Membrane microviscosity does not correlate with blood pressure: a cosegregation study.
McLaren, Y. and Kreutz, R. and Lindpaintner, K. and Bohr, D.F. and Ganten, D. and Reid, J.L. and Dominiczak, A.F.
Journal of Hypertension 11 : 25-30. 1 January 1993

Modulation of blood pressure and the renin-angiotensin system in transgenic and spontaneously hypertensive rats after ovariectomy.
Bachmann, J. and Wagner, J. and Haufe, C. and Wystrychowski, A. and Ciechanowicz, A. and Ganten, D.
Journal of Hypertension 11 (Suppl.5) : S226-S227. 1 January 1993

Modulation of tissue angiotensinogen gene expression by glycocorticoids, estrogens, and androgens in SHR and WKY rats.
Klett, C. and Hellmann, W. and Hackenthal, E. and Ganten, D.
Clinical and Experimental Hypertension 15 : 683-708. 1 January 1993

Molecular genetics of the SA-gene : cosegregation with hypertension and mapping to rat chromosome 1.
Lindpaintner, K. and Hilbert, P. and Ganten, D. and Nadal-Ginard, B. and Inagami, T. and Iwai, N.
Journal of Hypertension 11 (1): 19-23. 1 January 1993

Molekulare Medizin: Die Zukunft hat begonnen - ein Lichtblick fuer die Medizin von morgen.
Ganten, D.
Muenchener Medizinische Wochenschrift 135 : 12-13. 1 January 1993

Novel aspects on central 5 hydroxytryptamine neurotransmission focus on the cerebellum.
Fuxe, K. and Agnati, L.F. and Bjelke, B. and Hedlund, P. and Ueki, A. and Tinner, B. and Bunnemann, B. and Steinbusch, H. and Ganten, D. and Cintra, A.
In: Serotonin, the Cerebellum, and Ataxia : Meeting, Lyon, France, September 1991. Raven Press, New York, 1-36. 1 January 1993

Ontogenetic regulation of the mouse Ren-2d renin gene in transgenic hypertensive rats TGR(mREN2)27.
Zhao, Y. and Bader, M. and Kreutz, R. and Fernandez-Alfonso, M.S. and Zimmermann, F. and Ganten, U. and Metzger, R. and Ganten, D. and Mullins, J.J. and Peters, J.
American Journal of Physiology 265 : E699-E707. 1 January 1993

Photochemically induced focal cerebral ischemia in rat: time dependent and global increase in expression of basic fibroblast growth factor mRNA.
Lippoldt, A. and Andbjer, B. and Rosen, L. and Richter, E. and Ganten, D. and Cao, Y. and Pettersson, R.F. and Fuxe, K.
Brain Research 625 : 45-56. 1 January 1993

Polymorphism of the angiotensin-I converting enzyme gene Is apparently not related to high blood pressure - dutch hypertension and offspring study.
Schmidt, S. and Vanhooft, I.M.S. and Grobbee, D.E. and Ganten, D. and Ritz, E.
Journal of Hypertension 11 : 345-348. 1 January 1993

Primaerer Hyperrenismus. Eine seltene Ursache der sekundaeren arteriellen Hypertonie.
Kreutz, R. and Zhou, H. and Pfeifer, U. and Gasc, J.M. and Ganten, D. and Kessler, F.J.
Deutsche Medizinische Wochenschrift 118 : 1110-1114. 1 January 1993

Progress in molecular medicine. From experimental genetics to the treatment of hypertensive patients.
Ganten, D. and Kreutz, R. and Bader, M. and Wagner, J.
Chinese Medical Journal 106 : 375-384. 1 January 1993

Progress in molecular medicine: methods and their application in hypertension research.
Ganten, D.
In: Herkunft, Krise und Wandlung der modernen Medizin. Kulturgeschichtliche, wissenschaftsphilosophische und anthropologische Aspekte. Kleine, Bielefeld, 394-415. 1 January 1993

Regional expression of angiotensinogen messenger RNA in the brain of one-week-old, adult and old male rats.
Bunnemann, B. and Metzger, R. and Fuxe, K. and Ganten, D.
Developmental Brain Research 73 : 41-45. 1 January 1993

Regulation adrenaler Aldosteronsekretion und adrenalen Renins in TGR(mREN2)27.
Peters, J. and Djavidani, B. and Sander, M. and Bader, M. and Ganten, D.
Nieren- und Hochdruckkrankheiten 22 : 364-368. 1 January 1993

Regulation der Herzfunktion: Bedeutung der intrazellulaeren Proteinphosphorylierung.
Krause, E.G. and Bartel, S. and Karczewski, P. and Lindeke, A.
In: Zellulaere Mechanismen der Herz-Keislaufregulation. Pharmakologische und klinische Konsequenzen. Schattauer, Stuttgart [u.a.], 69-80. 1 January 1993

Renin gene expression and hypertension in transgenic animals.
Bader, M. and Lee, M.A. and Zhao, Y. and Boehm, M. and Bachmann, J. and Sander, M. and Djavidani, B. and Bachmann, S. and Zimmermann, F. and Wilbertz, J. and Zeh, K. and Wagner, J. and Peters, J. and Ganten, D.
In: Cellular and Molecular Biology of the Renin-Angiotensin System. CRC Press, Boca Raton, 60-93. 1 January 1993

Round table 1. Do transgenic techniques help us to understand hypertension?
Unger, T. and Ganten, D. and Johnston, C.I. and Lever, A.F. and Mullins, J.J. and Sassard, J. and van Zwieten, P.A.
Journal of Hypertension 11 (Suppl.5) : S374-S379. 1 January 1993

Sexual dimorphism of cardiovascular function: the role of androgens.
Bachmann, J. and Ganten, U. and Stock, G. and Ganten, D.
In: Sex Steroids and the Cardiovascular System (Schering Foundation Workshop ; 5). Springer, Berlin [u.a.], 9-30. 1 January 1993

The human renin-angiotensin system in transgenic rats - new tools for antihypertensive therapy.
Wagner, J. and Paul, M. and Ganten, D.
In: Transgenic Animals as Model Systems for Human Diseases (Schering Foundation Workshop ; 6). Springer, Berlin [u.a.], 1-23. 1 January 1993

The renin-angiotensin paradigm. practical therapeutical consequences of basic research.
Ganten, D.
Arzneimittelforschung 43 : 191-197. 1 January 1993

The renin-angiotensin system in the brain. Localization and functional significance.
Paul, M. and Bader, M. and Steckelings, U.M. and Voigtlaender, T. and Ganten, D.
Arzneimittelforschung 43 : 207-213. 1 January 1993

The renin-angiotensin system in transgenic rats : characteristics and functional studies.
Wagner, J. and Ganten, D.
Seminars in Nephrology 13 : 586-592. 1 January 1993

The transition from experimental to clinical pharmacology: the renin-angiotensin paradigm.
Ganten, D.
Journal of Cardiovascular Pharmacology 22 (Suppl.1) : S14-S29. 1 January 1993

Tissue distribution of angiotensinogen mRNA during experimental inflammation.
Klett, C. and Hellmann, W. and Ganten, D. and Hackenthal, E.
Inflammation 17 : 183-197. 1 January 1993

Transgenic rats as models to study candidate genes for hypertension.
Paul, M. and Ganten, D.
In: Progress in Endocrinology, Ninth International Congress of Endocrinology, Nice, France, September 1992. International Congress Symposium and Seminars Series ; 3 . Parthenon, London, 71-73. 1 January 1993

Update on the renin-angiotensin system. Recent advances in molecular biology.
Wagner, J. and Fernandez-Alfonso, M.S. and Bachmann, J. and Bader, M. and Paul, M. and Ganten, D.
Nutrition, Metabolism, and Cardiovascular Diseases 3 : 197-203. 1 January 1993

Vascular conversion of angiotensin I in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats.
Hilgers, K.F. and Veelken, R. and Mai, M. and Ganten, U. and Ganten, D. and Luft, F.C. and Mann, J.F.
Journal of Hypertension 11 : 1053-1059. 1 January 1993

WHL Hypertension League-Yearbook 1993.
Ganten, D. and Strasser, T. and Poetzsch, J.
WHO, Geneva. 1 January 1993

Zellulaere Mechanismen der Herz-Kreislaufregulation: Pharmakologische und klinische Konsequenzen. Franz Gross Hypertonie Symposium, Schlosshotel Kronberg, 5.-7. Maerz 1992.
Ganten, D.
Schattauer, Stuttgart. 1 January 1993

1992

The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27.
Sander, M. and Bader, M. and Djavidani, B. and Masergluth, C. and Vecsei, P. and Mullins, J.J. and Ganten, D. and Peters, J.
Endocrinology 131 (2): 807-814. 1 August 1992

Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes.
Ganten, D. and Wagner, J. and Zeh, K. and Bader, M. and Michel, J.B. and Paul, M. and Zimmermann, F. and Ruf, P. and Hilgenfeldt, U. and Ganten, U. and Kaling, M. and Bachmann, S. and Fukamizu, A. and Mullins, J.J. and Murakami, K.
Proceedings of the National Academy of Sciences of the United States of America 89 : 7806-7810. August 1992

Rat gene mapping using PCR-analyzed microsatellites.
Serikawa, T. and Kuramoto, T. and Hilbert, P. and Mori, M. and Yamada, J. and Dubay, C.J. and Lindpaintner, K. and Ganten, D. and Guenet, J.L. and Lathrop, G.M. and Beckmann, J.S.
Genetics 131 (3): 701-721. 1 July 1992

Increased vascular angiotensin formation in female rats harboring the mouse ren-2 gene.
Hilgers, K.F. and Peters, J. and Veelken, R. and Sommer, M. and Rupprecht, G. and Ganten, D. and Luft, F.C. and Mann, J.F.
Hypertension 19 (6 Pt 2): 687-691. 1 June 1992

Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats.
Bader, M. and Zhao, Y. and Sander, M. and Lee, M.A. and Bachmann, J. and Boehm, M. and Djavidani, B. and Peters, J. and Mullins, J.J. and Ganten, D.
Hypertension 19 (6 Pt 2): 681-686. 1 June 1992

Adrenal renin is released into the circulation of the hypertensive transgenic rat TGR(mRen-2)27.
Tokita, Y. and Yamaguchi, T. and Franco-Saenz, R. and Mulrow, P.J. and Ganten, D.
Transactions of the Association of American Physicians CV : 123-132. 1 January 1992

Basic methodology in the molecular characterization of genes.
Bader, M. and Kaling, M. and Metzger, R. and Peters, J. and Wagner, J. and Ganten, D.
Journal of Hypertension 10 : 9-16. 1 January 1992

Chromosomal mapping of genetic loci associated with hereditary hypertension in the rat.
Lindpaintner, K. and Hilbert, P. and Ganten, D. and Georges, M. and Lathrop, G.M.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats and Related Studies. Colloque Inserm ; 218 . John Libbey Eurotext, Paris, 313-315. 1 January 1992

Contributions of animal models for understanding hypertension.
Linz, W. and Ganten, D.
Progress in Cardiology 5 : 25-36. 1 January 1992

Correct expression of the transgene in the brain of hypertensive transgenic mice carrying the rat angiotensinogen gene.
Bunnemann, B. and Kimura, S. and Mullins, J.J. and Zimmermann, F. and Ganten, D. and Kaling, M.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertension Rats and Related Studies. Colloque Inserm ; 218 . John Libbey Eurotext, Paris, 309-311. 1 January 1992

Effects of angiotensin-converting enzyme inhibitors on tissue renin angiotensin systems.
Lee, M.A. and Paul, M. and Boehm, M. and Ganten, D.
American Journal of Cardiology 70 : C12-C19. 1 January 1992

Expression des Ren-2-Gens der Maus im Duenndarm von DBA/2-Maeusen und transgenen Ratten.
Zhao, Y. and Peters, J. and Matsuda, T. and Mullins, J.J. and Bader, M. and Ganten, D.
Nieren- und Hochdruckkrankheiten 21 : 642-643. 1 January 1992

Gefaess- und Herzhypertrophie : von der Molekularbiologie zur Therapie : Franz-Gross-Hypertonie-Symposium, Schlosshotel Kronberg, 7. - 9. Maerz 1991.
Ganten, D.
Schattauer, Stuttgart [u.a.]. 1 January 1992

Genetic mapping in hypertension.
Dzau, V.J. and Jacob, H.J. and Lindpaintner, K. and Ganten, D. and Lander, E.S.
Journal of Vascular Surgery 15 : 930-930. 1 January 1992

Genetic variation in hypertensive and control strains - what are we controlling for anyway (editorial).
Lindpaintner, K. and Kreutz, R. and Ganten, D.
Hypertension 19 : 428-430. 1 January 1992

Gesteigerte Aldosteronbiosynthese in TGR(mREN2)27: Funktionelle Bedeutung eines lokalen intraadrenalen Renin-Angiotensin-Systems.
Peters, J. and Djavidani, B. and Muenter, K. and Bader, M. and Sander, M. and Mullins, J.J. and Ganten, D.
Nieren- und Hochdruckkrankheiten 21 : 545-546. 1 January 1992

High blood pressure in transgenic mice carrying the rat angiotensinogen gene.
Kimura, S. and Mullins, J.J. and Jacob, H.J. and Fuxe, K. and Ganten, D. and Kaling, M.
EMBO Journal 11 : 821-827. 1 January 1992

Identification of chromosomal loci associated with genetic hypertension in the rat.
Lindpaintner, K. and Hilbert, P. and Ganten, D. and Georges, M. and Lathrop, M.
Nieren- und Hochdruckkrankheiten 21 : 549-551. 1 January 1992

Left ventricular remodeling after myocardial infarction - does the cardiac renin angiotensin system play a role?
Lindpaintner, K. and Niedermaier, N. and Drexler, H. and Ganten, D.
Journal of Cardiovascular Pharmacology 20 : S41-S47. 1 January 1992

Maligne Hypertonie: Pathophysiologie - Klinik - Therapie.
Wagner, J. and Ritz, E. and Ganten, D.
Deutsches Aerzteblatt 89 : 2624-2629. 1 January 1992

Mechanisms of cardiac growth. The role of the renin-angiotensin system.
Fernandez-Alfonso, M.S. and Ganten, D. and Paul, M.
Basic Research in Cardiology 87 : 173-181. 1 January 1992

Molecular genetics of hypertension.
Kreutz, R. and Higuchi, M. and Ganten, D.
Clinical and Experimental Hypertension : 15-34. 1 January 1992

Molekulare Genetik der Hypertonie.
Ganten, D. and Pfaff, G.M. and Kreutz, R.
Nieren- und Hochdruckkrankheiten 21 : 540-544. 1 January 1992

Molekulargenetik bei arterieller Hypertonie.
Kreutz, R. and Peters, J. and Ganten, D.
Deutsche Medizinische Wochenschrift 117 : 1461-1461. 1 January 1992

Molekulargenetische Marker sollen Hochdruck-Forschung vorantreiben. Das Renin-Gen hat eine pathophysiologische Relevanz fuer die Hypertonie.
Ganten, D. and Kreutz, R. and Lindpaintner, K.
Aerzte Zeitung 135 : 11-13. 1 January 1992

Pharmacology of Antihypertensive Therapeutics.
Ganten, D. and Bartsch, W.
Handbook of Experimental Pharmacology ; 93 . Springer, Berlin [u.a.]. 1 January 1992

Primary hypertension and the renin angiotensin system - from the laboratory experiment to clinical relevance.
Bader, M. and Kreutz, R. and Wagner, J. and Zeh, K. and Boehm, M. and Paul, M. and Ganten, D.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats, (Colloque Inserm ; 218). John Libbey Eurotext, Paris, 359-371. 1 January 1992

Primary hypertension in Germany: Epidemiology and treatment.
Wagner, J. and Haufe, C.C. and Ganten, D.
Curr Circ 3 : 21-24. 1 January 1992

Regulation der Herzmuskelzelle auf molekularer Ebene : Pharmakologische und klinische Bedeutung. Franz-Gross-Hypertonie-Symposium Kronberg, 5. - 7. Maerz 1992.
Ganten, D. and Mall, G. and Hofmann, F.
Fortschritte der Medizin 110 (Suppl 126): 2-19. 1 January 1992

Regulation of hepatic angiotensinogen synthesis and secretion by steroid hormones.
Klett, C. and Ganten, D. and Hellmann, W. and Kaling, M. and Ryffel, G.U. and Weimarehl, T. and Hackenthal, E.
Endocrinology 130 : 3660-3668. 1 January 1992

Renale Renin-mRNA-Expression bei Patienten mit Glomerulonephritis und Hypertonie.
Wagner, J. and Paul, M. and Haufe, C.C. and Volk, S. and Ganten, D. and Ritz, E.
Nieren- und Hochdruckkrankheiten 21 : 547-548. 1 January 1992

Report on the Hypertension Summer School (HTSS) Sept. 15-20, 1991.
Ganten, D.
Journal of Human Hypertension 6 : 247-247. 1 January 1992

Role of endocrine brain in the control of hypertension angiotensin II and atrial natriuretic peptide in the brain.
Badoer, E. and Unger, T. and Ganten, D.
In: Comprehensive Endocrinology : Brain Endocrinology. Raven Press, New York, 403-430. 1 January 1992

Search for genetic determinants of environmental susceptibility in hypertension: effect of heat, immobilization stress and endotoxin.
Kunes, J. and Pravenec, M. and Kren, V. and Klir, P. and Ganten, D. and Mullins, J.J. and Tremblay, J. and Hamet, P.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats. Colloque Inserm ; 218 . John Libbey Eurotext, Paris, 333-335. 1 January 1992

Sexual dimorphism of blood pressure in transgenic rats TGR(m REN2)27 harboring the murine Ren-2 gene.
Bachmann, J. and Ganten, U. and Zimmermann, F. and Mullins, J.J. and Stock, G. and Ganten, D.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats and Related Studies. Colloque Inserm ; 218 . John Libbey Eurotext, Paris, 353-355. 1 January 1992

Sexueller Dimorphismus des Blutdrucks bei TGR(mREN2)27: Einfluss von Androgenen.
Bachmann, J. and Ganten, U. and Stock, G. and Ganten, D.
Nieren- und Hochdruckkrankheiten 21 : 599-601. 1 January 1992

The Gross, Franz Hypertension Symposium Series - Introduction.
Ganten, D.
Journal of Cardiovascular Pharmacology 20 : 5-6. 1 January 1992

The brain renin-angiotensin system - localization and general significance.
Bunnemann, B. and Fuxe, K. and Ganten, D.
Journal of Cardiovascular Pharmacology 19 (Suppl 6): S51-S62. 1 January 1992

The brain renin-angiotensin system: a model for the synthesis of peptides in the brain (Commentary).
Ganten, D. and Speck, G.
Biochemical Pharmacology 27 : 2379-2389. 1 January 1992

The distribution of angiotensin II AT1 receptor subtype messenger RNA in the rat brain.
Bunnemann, B. and Iwai, N. and Metzger, R. and Fuxe, K. and Inagami, T. and Ganten, D.
Neuroscience Letters 142 : 155-158. 1 January 1992

The molecular basis of cardiovascular hypertrophy: the role of the renin angiotensin system.
Paul, M. and Ganten, D.
Journal of Cardiovascular Pharmacology 19 (Suppl 5): S51-S58. 1 January 1992

The role of adrenal renin in steroid metabolism and development of hypertension in transgenic rats TGR(Messenger REN2).
Peters, J. and Sander, M. and Munter, K. and Lee, M.A. and Djavidani, B. and Bader, M. and Maser-Gluth, C. and Vecsei, P. and Ganten, D. and Mullins, J.J.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats (Colloque Inserm ; 218). John Libbey Eurotext, Paris, 345-347. 1 January 1992

The semi-quantitative distribution and cellular localization of angiotensinogen messenger RNA in the rat brain.
Bunnemann, B. and Fuxe, K. and Metzger, R. and Bjelke, B. and Ganten, D.
Journal of Chemical Neuroanatomy 5 : 245-262. 1 January 1992

The tissue renin-angiotensin systems in cardiovascular disease.
Paul, M. and Bachmann, J. and Ganten, D.
Trends in Cardiovascular Medicine 2 : 94-99. 1 January 1992

Transgenic rats carrying the mouse renin gene - morphological characterization of a low-renin hypertension model.
Bachmann, S. and Peters, J. and Engler, E. and Ganten, D. and Mullins, J.J.
Kidney International 41 : 24-36. 1 January 1992

Wissenschaft - Wirtschaft - Oeffentlichkeit : Gemeinsames und Trennendes, Bruecken und Huerden in der Forschung. Konferenz der Akademien der Wissenschaften der Bundesrepublik Deutschland.
Schettler, G. and Ganten, D. and Baildon, R.
Springer, Berlin [u.a.]. 1 January 1992

Zonal distribution and regulation of adrenal renin in a transgenic model of hypertension in the rat.
Yamaguchi, T. and Tokita, Y. and Franco-Saenz, R. and Mulrow, P.J. and Peters, J. and Ganten, D.
Endocrinology 131 : 1955-1962. 1 January 1992

Cardiovascular hypertrophy: from molecular biology to clinics, therapy, and prevention. Franz Gross Hypertension Symposium. Kronberg, March 7-9, 1991.
Ganten, Detlev, ed.
Journal of Cardiovascular Pharmacology, 20 (Suppl 1). Raven Press, New York, S1-64. 1992

1991

The influence of cold stress on the myosin heavy chain expression of cardiac and smooth muscle in normotensive and spontaneously hypertensive female rats.
Adler, K. and Boels, P. and Ganten, U. and Ganten, D. and Morano, I.
Circulation Research 69 (6): 1640-1644. December 1991

Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats.
Hilbert, P. and Lindpaintner, K. and Beckmann, J.S. and Serikawa, T. and Soubrier, F. and Dubay, C.J. and Cartwright, P. and De Gouyon, B. and Julier, C. and Takahashi, S. and Vincent, M. and Ganten, D. and Georges, M. and Lathrop, G.M.
Nature 353 (6344): 521-529. 10 October 1991

Genetic mapping of a gene causing hypertension in the stroke- prone spontaneously hypertensive rat.
Jacob, H.J. and Lindpaintner, K. and Lincoln, S.E. and Kusumi, K. and Bunker, R.K. and Mao, Y.P. and Ganten, D. and Dzau, V.J. and Lander, E.S.
Cell 67 (1): 213-224. 4 October 1991

Angiotensin II immunoreactivity in the human striatum and hippocampus of elderly controls and patients with senile dementia of the Alzheimer type and multi-infarct dementia.
Savaskan, E. and Hoechli, M. and Ganten, D. and Chan-Palay, V.
Dementia 2 : 314-323. 1 January 1991

Angiotensin and cell growth: a link to cardiovascular hypertrophy? [editorial].
Schelling, P. and Fischer, H. and Ganten, D.
Journal of Hypertension 9 : 3-15. 1 January 1991

Angiotensin in hypertension: new aspects.
Ganten, D. and Paul, M. and Bader, M. and Mullins, J.J.
In: Peptide Regulation of Cardiovascular Function. Academic Press, Tokyo, 167-190. 1 January 1991

Blutdruckselbstmessung.
Baildon, R. and Ganten, D.
Allgemeinarzt 8 : 616-619. 1 January 1991

Cell biology in hypertension.
Kreutz, R. and Ganten, D.
Current Opinion in Cardiology 6 : 680-685. 1 January 1991

Changes in the central ANF-system of renovascular hypertensive rats.
Bahner, U. and Geiger, H. and Palkovits, M. and Ganten, D. and Klotz, B. and Heidland, A.
Kidney International 39 : 33-38. 1 January 1991

Characterization of rat intestinal angiotensin II receptors.
Schinke, M. and Doods, H.N. and Ganten, D. and Wienen, W. and Entzeroth, M.
European Journal of Pharmacology 204 : 165-170. 1 January 1991

Das Renin-Angiotensin-System im Gehirn.
Ganten, D. and Bunnemann, B. and Fuxe, K.
In: Herz-Kreislauf-Regulation, Organprotektion und Organschaeden. Schattauer, Stuttgart, 177-183. 1 January 1991

Die Bedeutung extrarenaler Reninsysteme in der Pathogenese der arteriellen Hypertonie.
Paul, M. and Ganten, D.
Verhandlungen der Deutschen Gesellschaft fuer Innere Medizin 97 : 539-544. 1 January 1991

Differences in rat kidney morphology between males, females and testosterone-treated females.
Oudar, O. and Elger, M. and Bankir, L. and Ganten, D. and Ganten, U. and Kriz, W.
Renal Physiology and Biochemistry 14 : 92-102. 1 January 1991

Enhanced cardiac angiotensinogen gene expression and angiotensin converting enzyme activity in tachypacing-induced heart failure in rats.
Finckh, M. and Hellmann, W. and Ganten, D. and Furtwangler, A. and Allgeier, J. and Boltz, M. and Holtz, J.
Basic Research in Cardiology 86 : 303-316. 1 January 1991

Extrarenal Systems: the Brain.
Bunnemann, B. and Fuxe, K. and Ganten, D.
In: The Renin-Angiotensin System, Volume 1: Biochemistry Physiology. Gower Medical Publishing, London [u.a.], 41.1-41.17. 1 January 1991

Funktionelle Bedeutung des kardialen Renin-Angiotensin-Sytems.
Dietz, R. and Waas, W. and Haberbosch, W. and Suesselbeck, T. and Hauck, S. and Osterziel, K.J.
In: Herz-Kreislauf-Regulation, Organprotektion und Organschaeden. Schattauer, Stuttgart [u.a.], 193-202. 1 January 1991

Genetic basis of hypertension.
Ganten, D. and Takahashi, S. and Lindpaintner, K. and Mullins, J.J.
Hypertension 18 : III109-III114. 1 January 1991

Glucocorticoid- and estrogen-responsive elements in the 5'- flanking region of the rat angiotensinogen gene.
Feldmer, M. and Kaling, M. and Takahashi, S. and Mullins, J.J. and Ganten, D.
Journal of Hypertension 9 : 1005-1012. 1 January 1991

Herz-Kreislauf-Regulation, Organprotektion und Organschaeden : Franz Gross Hypertonie Symposium, Schlosshotel Kronberg, 1. - 3. Maerz 1990.
Ganten, D. and Mall, G.
Schattauer, Stuttgart [u.a.]. 1 January 1991

Kardiovaskulaere Hypertrophie: Bedeutung des Renin-Angiotensin Systems.
Paul, M. and Wagner, J. and Ganten, D.
In: Herz-Kreislauf-Regulation, Organprotektion und Organschaeden. Schattauer, Stuttgart, 99-108. 1 January 1991

Local angiotensin formation in hindlimbs of uremic hypertensive and renovascular hypertensive rats.
Kuczera, M. and Hilgers, K.F. and Lisson, C. and Ganten, D. and Hilgenfeldt, U. and Ritz, E. and Mann, J.F.
Journal of Hypertension 9 : 41-48. 1 January 1991

Molekulare Genetik des Bluthochdrucks.
Kreutz, R. and Lindpaintner, K. and Ganten, D.
Muenchener Medizinische Wochenschrift 133 : 724-728. 1 January 1991

Preparation and analysis of transgenic rats expressing the mouse Ren-2 gene.
Lee, M.A. and Zhao, Y. and Peters, J. and Ganten, D. and Zimmermann, F. and Ganten, U. and Bachmann, S. and Bader, M. and Mullins, J.J.
Journal of Vascular Medicine and Biology 3 : 50-54. 1 January 1991

Sexual dimorphism of blood pressure: possible role of the renin- angiotensin system.
Bachmann, J. and Feldmer, M. and Ganten, U. and Stock, G. and Ganten, D.
Journal of Steroid Biochemistry and Molecular Biology 40 : 511-515. 1 January 1991

The brain renin angiotensin system and its possible involvement in volume transmission.
Bunnemann, B. and Fuxe, K. and Bjelke, B. and Ganten, D.
In: Volume Transmission in the Brain : Novel Mechanisms for Neural Transmission , Conference, Stockholm, Sweden, September 28-30, 1989 (Advances in Neuroscience ; 1). Raven Press, New York, 131-158. 1 January 1991

The cardiac renin-angiotensin system. An appraisal of present experimental and clinical evidence.
Lindpaintner, K. and Ganten, D.
Circulation Research 68 : 905-921. 1 January 1991

The cardiac renin-angiotensin system: a synopsis of current experimental and clinical data.
Lindpaintner, K. and Ganten, D.
News in Physiological Sciences 6 : 227-232. 1 January 1991

The cardiac renin-angiotensin system: a synopsis of current experimental and clinical data.
Lindpaintner, K. and Ganten, D.
Acta Cardiologica 46 : 385-397. 1 January 1991

The role of neuropeptides in cardiovascular regulation.
Ganten, D. and Paul, M. and Lang, R.E.
Cardiovascular Drugs and Therapy 5 : 119-130. 1 January 1991

Tissue distribution of ren-2 expression in transgenic rats.
Peters, J. and Bader, M. and Ganten, D. and Mullins, J.J.
In: Genetic Approaches to Coronary Heart Disease and Hypertension. Springer, Berlin [u.a.], 74-80. 1 January 1991

Tissue renin-angiotensin systems and their modulation: the heart as a paradigm for new aspects of converting enzyme inhibition.
Lindpaintner, K. and Ganten, D.
Cardiology 79 (Suppl 1): 32-44. 1 January 1991

Transgenic rats: new animal models in hypertension research. Invited lecture.
Ganten, D. and Lindpaintner, K. and Ganten, U. and Peters, J. and Zimmermann, F. and Bader, M. and Mullins, J.J.
Hypertension 17 : 843-855. 1 January 1991

Vascular production and regulation of angiotensin.
Hilgers, K.F. and Mann, J.F. and Hilgenfeldt, U. and Ganten, D.
Blood Vessels 28 : 201-209. 1 January 1991