Browse by Research Team

2012

Evolutionary molecular medicine.
Nesse, R.M., Ganten, D., Gregory, T.R. and Omenn, G.S.
Journal of Molecular Medicine 90 (5): 509-522. May 2012

The evolution of evolutionary molecular medicine : Genomics are transforming evolutionary biology into a science with new importance for modern medicine.
Ganten, D. and Nesse, R.
Journal of Molecular Medicine 90 (5): 467-470. May 2012

2008

Estrogen, nitric oxide, and hypertension differentially modulate agonist-induced contractile responses in female transgenic (mRen2)27 hypertensive rats.
Brosnihan, K.B., Li, P., Figueroa, J.P., Ganten, D. and Ferrario, C.M.
American Journal of Physiology Heart and Circulatory Physiology 294 (5): H1995-H2001. 1 May 2008

2007

Primary role of angiotensin converting enzyme 2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats.
Trask, A.J., Averill, D.B., Ganten, D., Chappell, M.C. and Ferrario, C.M.
American Journal of Physiology Heart and Circulatory Physiology 292 (6): H3019-H3024. 1 June 2007

2006

Rats with low brain angiotensinogen do not exhibit insulin resistance during early aging.
Kasper, S.O., Ferrario, C.M., Ganten, D. and Diz, D.I.
Endocrine 30 (2): 167-174. October 2006

Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine.
Ganten, D. and Ruckpaul, K.
Springer, Berlin [u.a.]. ISBN 3-540-44244-8 2006

Molekularmedizinische Grundlagen von para- und autokrinen Regulationsstoerungen.
Ganten, D., Ruckpaul, K. and Koehrle, J.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-28781-7 2006

2005

Growth, metabolism and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems.
Kasper, S.O., Carter, C.S., Ferrario, C.M., Ganten, D., Ferder, L.F., Sonntag, W.E., Gallagher, P.E. and Diz, D.I.
Physiological Genomics 23 : 311-317. 30 August 2005

Effects of sodium restriction and cyclooxygenase-2 inhibition on the course of hypertension, proteinuria and cardiac hypertrophy in Ren-2 transgenic rats.
Vaneckova, I., Skaroupkova, P., Dvorak, P., Certikova-Chabova, V., Tesar, V., Bader, M., Ganten, D. and Kramer, J.J.
Physiological Research 54 (1): 17-24. 1 January 2005

Identification of hypertension-related genes through an integrated genomic-transcriptomic approach.
Yagil, C., Huebner, N., Monti, J., Schulz, H., Sapojnikov, M., Luft, F.C., Ganten, D. and Yagil, Y.
Circulation Research 96 (6): 617-625. 1 January 2005

Molekularmedizinische Grundlagen von fetalen und neonatalen Erkrankungen.
Ganten, D, Ruckpaul, K and Wauer, RR, eds.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-20138-6 1 January 2005

Prevention of cardiac remodeling after myocardial infarction in transgenic rats deficient in brain angiotensinogen.
Lal, A., Veinot, J.P., Ganten, D. and Leenen, F.H.H.
Journal of Molecular and Cellular Cardiology 39 (3): 521-529. 1 January 2005

Roles of nitric oxide and oxidative stress in the regulation of blood pressure and renal function in prehypertensive Ren-2 transgenic rats.
Vaneckova, I., Kramer, H.J., Novotna, J., Kazdova, L., Opocensky, M., Bader, M., Ganten, D. and Cervenka, L.
Kidney and Blood Pressure Research 28 (2): 117-126. 1 January 2005

2004

Differential regulation of central vasopressin receptors in transgenic rats with low brain angiotensinogen.
Campos, L.A., Couto, A.S., Iliescu, R., Santos, J.A., Santos, R.A.S., Ganten, D., Campagnole-Santos, M.J., Bader, M. and Baltatu, O.
Regulatory Peptides 119 (3): 177-182. 15 July 2004

Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs, R.A., Weinstock, G.M., Metzker, M.L., Muzny, D.M., Sodergren, E.J., Scherer, S., Scott, G., Steffen, D., Worley, K.C., Burch, P.E., Okwuonu, G., Hines, S., Lewis, L., DeRamo, C., Delgado, O., Dugan-Rocha, S., Miner, G., Morgan, M., Hawes, A., Gill, R., Holt, R.A., Adams, M.D., Amanatides, P.G., Baden-Tillson, H., Barnstead, M., Chin, S., Evans, C.A., Ferriera, S., Fosler, C., Glodek, A., Gu, Z., Jennings, D., Kraft, C.L., Nguyen, T., Pfannkoch, C.M., Sitter, C., Sutton, G.G., Venter, J.C., Woodage, T., Smith, D., Lee, H.M., Gustafson, E., Cahill, P., Kana, A., Doucette-Stamm, L., Weinstock, K., Fechtel, K., Weiss, R.B., Dunn, D.M., Green, E.D., Blakesley, R.W., Bouffard, G.G., de Jong, P.J., Osoegawa, K., Zhu, B., Marra, M., Schein, J., Bosdet, I., Fjell, C., Jones, S., Krzywinski, M., Mathewson, C., Siddiqui, A., Wye, N., McPherson, J., Zhao, S., Fraser, C.M., Shetty, J., Shatsman, S., Geer, K., Chen, Y., Abramzon, S., Nierman, W.C., Havlak, P.H., Chen, R., Durbin, K.J., Egan, A., Ren, Y., Song, X.Z., Li, B., Liu, Y., Qin, X., Cawley, S., Worley, K.C., Cooney, A.J., D'Souza, L.M., Martin, K., Wu, J.Q., Gonzalez-Garay, M.L., Jackson, A.R., Kalafus, K.J., McLeod, M.P., Milosavljevic, A., Virk, D., Volkov, A., Wheeler, D.A., Zhang, Z., Bailey, J.A., Eichler, E.E., Tuzun, E., Birney, E., Mongin, E., Ureta-Vidal, A., Woodwark, C., Zdobnov, E., Bork, P., Suyama, M., Torrents, D., Alexandersson, M., Trask, B.J., Young, J.M., Huang, H., Wang, H., Xing, H., Daniels, S., Gietzen, D., Schmidt, J., Stevens, K., Vitt, U., Wingrove, J., Camara, F., Alba, M.M., Abril, J.F., Guigo, R., Smit, A., Dubchak, I., Rubin, E.M., Couronne, O., Poliakov, A., Hübner, N., Ganten, D., Goesele, C., Hummel, O., Kreitler, T., Lee, Y.A., Monti, J., Schulz, H., Zimdahl, H., Himmelbauer, H., Lehrach, H., Jacob, H.J., Bromberg, S., Gullings-Handley, J., Jensen-Seaman, M.I., Kwitek, A.E., Lazar, J., Pasko, D., Tonellato, P.J., Twigger, S., Ponting, C.P., Duarte, J.M., Rice, S., Goodstadt, L., Beatson, S.A., Emes, R.D., Winter, E.E., Webber, C., Brandt, P., Nyakatura, G., Adetobi, M., Chiaromonte, F., Elnitski, L., Eswara, P., Hardison, R.C., Hou, M., Kolbe, D., Makova, K., Miller, W., Nekrutenko, A., Riemer, C., Schwartz, S., Taylor, J., Yang, S., Zhang, Y., Lindpaintner, K., Andrews, T.D., Caccamo, M., Clamp, M., Clarke, L., Curwen, V., Durbin, R., Eyras, E., Searle, S.M., Cooper, G.M., Batzoglou, S., Brudno, M., Sidow, A., Stone, E.A., Venter, J.C., Payseur, B.A., Bourque, G., Lopez-Otin, C., Puente, X.S., Chakrabarti, K., Chatterji, S., Dewey, C., Pachter, L., Bray, N., Yap, V.B., Caspi, A., Tesler, G., Pevzner, P.A., Haussler, D., Roskin, K.M., Baertsch, R., Clawson, H., Furey, T.S., Hinrichs, A.S., Karolchik, D., Kent, W.J., Rosenbloom, K.R., Trumbower, H., Weirauch, M., Cooper, D.N., Stenson, P.D., Ma, B., Brent, M., Arumugam, M., Shteynberg, D., Copley, R.R., Taylor, M.S., Riethman, H., Mudunuri, U., Peterson, J., Guyer, M., Felsenfeld, A., Old, S., Mockrin, S. and Collins, F.
Nature 428 (6982): 493-521. 1 April 2004

Plasma and kidney angiotensin II levels and renal functional responses to AT1 receptor blockade in hypertensive Ren-2 transgenic rats.
Kopkan, L., Kramer, H.J., Huskova, Z., Vanourkova, Z., Baecker, A., Bader, M., Ganten, D. and Cervenka, L.
Journal of Hypertension 22 (4): 819-825. 1 April 2004

Integrated and sequence-ordered BAC- and YAC-based physical maps for the rat genome.
Krzywinski, M., Wallis, J., Gösele, C., Bosdet, I., Chiu, R., Graves, T., Hummel, O., Layman, D., Mathewson, C., Wye, N., Zhu, B., Albracht, D., Asano, J., Barber, S., Brown-John, M., Chan, S., Chand, S., Cloutier, A., Davito, J., Fjell, C., Gaige, T., Ganten, D., Girn, N., Guggenheimer, K., Himmelbauer, H., Kreitler, T., Leach, S., Lee, D., Lehrach, H., Mayo, M., Mead, K., Olson, T., Pandoh, P., Prabhu, A.L., Shin, H., Taenzer, S., Thompson, J., Tsai, M., Walker, J., Yang, G., Sekhon, M., Hillier, L., Zimdahl, H., Marziali, A., Osoegawa, K., Zhao, S., Siddiqui, A., de Jong, P.J., Warren, W., Mardis, E., McPherson, J.D., Wilson, R., Hübner, N., Jones, S., Marra, M. and Schein, J.
Genome Research 14 (4): 766-779. April 2004

Alterations in sympathetic ganglionic transmission in response to angiotensin II in (mRen2)27 transgenic rats.
Aileru, A.A., Logan, E., Callahan, M., Ferrario, C.M., Ganten, D. and Diz, D.I.
Hypertension 43 (2): 270-275. February 2004

A SNP map of the rat genome generated from cDNA sequences.
Zimdahl, H., Nyakatura, G., Brandt, P., Schulz, H., Hummel, O., Fartmann, B., Brett, D., Droege, M., Monti, J., Lee, Y.A., Sun, Y.Y., Zhao, S.Y., Winter, E.E., Ponting, C.P., Chen, Y., Kasprzyk, A., Birney, E., Ganten, D. and Hubner, N.
Science 303 (5659): 807-807. 1 January 2004

Acute effects of cyclooxygenase-2 inhibition on renal function in heterozygous Ren-2-transgenic rats on normal or low sodium intake.
Vaneckova, I., Cahova, M., Kramer, H.J., Huskova, Z., Skaroupkova, P., Komers, R., Bader, M., Ganten, D. and Cervenka, L.
Kidney and Blood Pressure Research 27 (4): 203-210. 1 January 2004

Blockade of endothelin receptors attenuates end-organ damage in homozygous hypertensive Ren-2 transgenic rats.
Dvorak, P., Kramer, H.J., Baecker, A., Maly, J., Kopkan, L., Vaneckova, I., Vernerova, Z., Opocensky, M., Tesar, V., Bader, M., Ganten, D., Janda, J. and Cervenka, L.
Kidney and Blood Pressure Research 27 (4): 248-258. 1 January 2004

Chronic endothelin receptor blockade reduces end-organ damage independently of blood pressure effects in salt-loaded heterozygous Ren-2 transgenic rats.
Opocensky, M., Dvorak, P., Maly, J., Kramer, H.J., Baecker, A., Kopkan, L., Vernerova, Z., Tesar, V., Zima, T., Bader, M., Ganten, D., Janda, J. and Vaneckova, I.
Physiological Research 53 (6): 581-593. 1 January 2004

Das estnische Genomprojekt im Kontext der europaeischen Genomforschung [The Estonian Genome Project in the context of European genome research].
Metspalu, A., Koehler, F., Laschinski, G., Ganten, D. and Roots, I.
Deutsche Medizinische Wochenschrift 129 : S25-S28. 1 January 2004

Efficiency of transgenic rat production is independent of transgene-construct and overnight embryo culture.
Popova, E., Krivokharchenko, A., Ganten, D. and Bader, M.
Theriogenology 61 (7-8): 1441-1453. 1 January 2004

Molecular analysis of the sex hormone-binding globulin gene in the rat hypodactylous mutation (Hd).
Liska, F., Gösele, C., Kren, V., Hübner, N. and Krenova, D.
Folia Biologica Prague 50 (2): 63-68. 1 January 2004

Molekularmedizinische Grundlagen von altersspezifischen Erkrankungen.
Ganten, D., Ruckpaul, K. and Ruiz-Torres, A.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-00858-6 1 January 2004

Prevention of sympathetic and cardiac dysfunction after myocardial infarction in transgenic rats deficient in brain angiotensinogen.
Wang, H., Huang, B.S., Ganten, D. and Leenen, F.H.H.
Circulation Research 94 (6): 843-849. 1 January 2004

Transgenics of the RAS.
Bader, M. and Ganten, D.
In: Angiotensin, Vol. 1. Handbook of Experimental Pharmacology ; 163, 1 . Springer, Berlin [u.a.], 229-249. ISBN 3-540-40640-9 1 January 2004

Central depletion of angiotensinogen is associated with elevated AT1 receptors in the SFO and PVN.
Kasper, S.O., Ferrario, C.M., Ganten, D. and Diz, D.I.
Neurotoxicity Rresearch 6 (4): 259-265. 2004

2003

Lipoic acid supplementation prevents angiotensin II-induced renal injury.
Mervaala, E., Finckenberg, P., Lapatto, R., Mueller, D.N., Park, J.K., Dechend, R., Ganten, D., Vapaatalo, H. and Luft, F.C.
Kidney International 64 (2): 501-508. August 2003

Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways.
Finckenberg, P., Inkinen, K., Ahonen, J., Merasto, S., Louhelainen, M., Vapaatalo, H., Müller, D., Ganten, D., Luft, F.C. and Mervaala, E.
American Journal of Pathology 163 (1): 355-366. July 2003

Genome-wide linkage reveals a locus for human essential (primary) hypertension on chromosome 12p.
Gong, M., Zhang, H.Y., Schulz, H., Lee, Y.A., Sun, K., Bähring, S., Luft, F.C., Nürnberg, P., Reis, A., Rohde, K., Ganten, D., Hui, R.T. and Hübner, N.
Human Molecular Genetics 12 (11): 1273-1277. 1 June 2003

Entwicklung eines genetischen Markersystems fuer das Rattengenom.
Rossmann, M.
UNSPECIFIED thesis, UNSPECIFIED. 11 April 2003

The role of Wnk4 in polygenic hypertension - A candidate gene analysis on rat chromosome 10.
Monti, J., Zimdahl, H., Schulz, H., Plehm, R., Ganten, D. and Hübner, N.
Hypertension 41 (4): 938-942. April 2003

Development of parthenogenetic rat embryos.
Krivokharchenko, A., Popova, E., Zaitseva, I., Vil'ianovich, L., Ganten, D. and Bader, M.
Biology of Reproduction 68 (3): 829-836. 1 March 2003

Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure.
Gotthardt, M., Hammer, R.E., Hübner, N., Monti, J., Witt, C.C., McNabb, M., Richardson, J.A., Granzier, H., Labeit, S. and Herz, J.
Journal of Biological Chemistry 278 (8): 6059-6065. 21 February 2003

Berlin - Stadt des Wissens? Deutschland braucht einen erlebbaren Ort der neuen humanen Wissensgesellschaft.
Ganten, D.
In: Berlin - was ist uns die Hauptstadt wert? Leske + Budrich, Opladen, 95-105. ISBN 3-8100-4054-1 1 January 2003

Congenic strains confirm the presence of salt-sensitivity QTLs on chromosome 1 in the Sabra rat model of hypertension.
Yagil, C., Hubner, N., Kreutz, R., Ganten, D. and Yagil, Y.
Physiological Genomics 12 : 85-95. 1 January 2003

Grundlagen der Molekularen Medizin.
Ganten, D. and Ruckpaul, K.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-43207-8 1 January 2003

Interaction between blood pressure quantitative trait loci in rats in which trait variation at chromosome 1 is conditional upon a specific allele at chromosome 10.
Monti, J., Plehm, R., Schulz, H., Ganten, D., Kreutz, R. and Hübner, N.
Human Molecular Genetics 12 (4): 435-439. 1 January 2003

Leben, Natur, Wissenschaft : Alles was man wissen muss.
Ganten, D., Deichmann, T. and Spahl, T.
Eichborn, Frankfurt/a.M.. ISBN 3-8218-3981-3 1 January 2003

Molekularmedizinische Grundlagen von haematologischen Neoplasien.
Ganten, D. and Ruckpaul, K.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-41640-4 1 January 2003

Molekularmedizinische Grundlagen von rheumatischen Erkrankungen.
Ganten, D. and Ruckpaul, K.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-41640-4 1 January 2003

Stammzellen.
Wormer, E.J., Kaufmann, W., Ganten, D. and Kempermann, G.
Themen der Zeit . Lingen Verl., Koeln. ISBN 3-937490-00-0 1 January 2003

Vorwort zu "Gentherapie: Hoffnungen und Hindernisse".
Ganten, D.
In: Gentherapie : Hoffnungen und Hindernisse. Strauss, Potsdam, 8-15. ISBN 3-929748-27-4 1 January 2003

Gezielte Zellvermehrung und spezifische Zelltransplantation. Ein Plaedoyer fuer die Stammzellforschung und fuer eine Klaerung der Begrifflichkeiten.
Ganten, D.
Zeitschrift fuer Biopolitik 2 (1): 25-33. 2003

2002

How to deal with scientific controversy?
Ganten, D.
Journal of Molecular Medicine 80 (12): 745-746. December 2002

Comparison between PMSG- and FSH-induced superovulation for the generation of transgenic rats.
Popova, E., Krivokharchenko, A., Ganten, D. and Bader, M.
Molecular Reproduction and Development 63 (2): 177-182. October 2002

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Özcelik, C., Erdmann, B., Pilz, B., Wettschureck, N., Britsch, S., Hübner, N., Chien, K.R., Birchmeier, C. and Garratt, A.N.
Proceedings of the National Academy of Sciences of the United States of America 99 (13): 8880-8885. 25 June 2002

Verwendung von aus embryonalen Stammzellen hergeleiteten Zellen zur Erhoehung der Transplantationstoleranz und zur Wiederherstellung zerstoerten Gewebes [Use of cells derived from embryonic stem cells for increasing transplantation tolerance and for repairing damaged tissue].
Bader, M., Binas, B., Chai, G., Faendrich, F., Ganten, D. and Lin, X.
DE10061334A1 ; EP1341915 ; WO0246401. 13 June 2002

Conserved synteny in rat and mouse for a blood pressure QTL on human chromosome 17.
Zimdahl, H., Kreitler, T., Gösele, C., Ganten, D. and Hübner, N.
Hypertension 39 (6): 1050-1052. 1 June 2002

Reduced hypertension-induced end-organ damage in mice lacking cardiac and renal angiotensinogen synthesis.
Kang, N.L., Walther, T., Tian, X.L., Bohlender, J., Fukamizu, A., Ganten, D. and Bader, M.
Journal of Molecular Medicine 80 (6): 359-366. June 2002

Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen.
Couto, A.S., Baltatu, O., Santos, R.A.S., Ganten, D., Bader, M. and Campagnole-Santos, M.J.
Journal of Hypertension 20 (5): 919-925. May 2002

Friedrich Cameron Luft turns 60: bridging the New and the Old World.
Ganten, D.
Journal of Molecular Medicine 80 (4): 197-199. April 2002

Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioning.
Faendrich, F., Lin, X., Chai, G.X., Schulze, M., Ganten, D., Bader, M., Holle, J., Huang, D.S., Parwaresch, R., Zavazava, N. and Binas, B.
Nature Medicine 8 : 171-178. 1 February 2002

Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats.
Theuer, J., Dechend, R., Muller, D.N., Park, J.K., Fiebeler, A., Barta, P., Ganten, D., Haller, H., Dietz, R. and Luft, F.C.
BMC Cardiovascular Disorders 2 : 3. 18 January 2002

A gene expression analysis in rat kidney following high and low salt intake.
Barta, P., Monti, J., Maass, P.G., Gorzelniak, K., Müller, D.N., Dechend, R., Luft, F.C., Hübner, N. and Sharma, A.M.
Journal of Hypertension 20 : 1115-1120. 1 January 2002

Congenic rat strains are important tools for the genetic dissection of essential hypertension.
Kreutz, R. and Hübner, N.
Seminars in Nephrology 22 (2): 135-147. 1 January 2002

Decreased susceptibility of cardiac function to hypoxia-reoxygenation in renin-angiotensinogen transgenic rats.
Wagner, K.D., Essmann, V., Mydlak, K., Wirth, M., Gmehling, G., Bohlender, J., Stauss, H.M., Gunther, J., Schimke, I. and Scholz, H.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 283 (1): R153-R160. 1 January 2002

In vitro formation of tetraploid rat blastocysts after fusion of two-cell embryos.
Krivokharchenko, A., Galat, V., Ganten, D. and Bader, M.
Molecular Reproduction and Development 61 (4): 460-465. 1 January 2002

It's renin in the brain - Transgenic animals elucidate the brain renin-angiotensin system.
Bader, M. and Ganten, D.
Circulation Research 90 (1): 8-10. 1 January 2002

Molekularmedizinische Grundlagen von nicht-hereditaeren Tumorerkrankungen.
Ganten, D. and Ruckpaul, K.
Molekulare Medizin, 10 . Springer, Berlin [u.a.]. ISBN 3-540-41577-7 1 January 2002

TNF-alpha-accelerated apoptosis abrogates ANCA-mediated neutrophil respiratory burst by a caspase-dependent mechanism.
Kettritz, R., Scheumann, J., Xu, Y.X., Luft, F.C. and Haller, H.
Kidney International 61 : 502-515. 1 January 2002

A prospective evaluation of the angiotensin-converting enzyme D/I polymorphism and left ventricular remodeling in the 'Healing and Early Afterload Reducing Therapy' Study.
Zee, R.Y.L., Solomon, S.D., Ajani, U.A., Pfeffer, M.A. and Lindpaintner, K.
Clinical Genetics 61 (1): 21-25. January 2002

Genomforschung und Biotechnologie in Deutschland.
Ganten, D.
In: Komplexe Langzeitvertraege fuer neue Technologien und neue Projekte. Heidelberger Kolloquium Technologie und Recht 2001. Beck, Muenchen, 55-61. ISBN 9783406497155 2002

Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.
Cervenka, L., Kramer, H.J., Maly, J., Vaneckova, I., Baecker, A., Bokemeyer, D., Bader, M., Ganten, D. and Mitchell, K.D.
Physiological Research 51 (6): 571-580. 2002

2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 79 (7): 353-354. July 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 79 (5-6): 224-225. June 2001

The Future of Molecular Medicine. 4th Berlin Colloquium of the Gottlieb Daimler and Karl Benz Foundation in co-operation with the Max Delbruck Center for Molecular Medicine (MDC), Berlin-Buch, on Wednesday, May 10, 2000 in Berlin at the Konrad Adenauer Fundation, Tiergartenstr. 35, D-10785 Berlin.
Ganten, D.
Molecular Aspects of Medicine 22 (3): 91-100. June 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 79 (4): 159-160. May 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 79 (2-3): 74-75. April 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 79 (1): 4-5. March 2001

Alterations in blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen.
Baltatu, O., Janssen, B.J., Bricca, G., Plehm, R., Monti, J., Ganten, D. and Bader, M.
Hypertension 37 (2): 408-413. 1 January 2001

Alterations of the renin-angiotensin system at the RVLM of transgenic rats with low brain angiotensinogen.
Baltatu, O., Fontes, M.A.P., Campagnole-Santos, M.J., Caligiorni, S., Ganten, D., Santos, R.A.S. and Bader, M.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 280 (2): R428-R433. 1 January 2001

Aspirin inhibits NF-kappa B and protects from angiotensin II-induced organ damage.
Mueller, D.N., Heissmeyer, V., Dechend, R., Hampich, F., Park, J.K., Fiebeler, A., Shagdarsuren, E., Theuer, J., Elger, M., Pilz, B., Breu, V., Schroer, K., Ganten, D., Dietz, R., Haller, H., Scheidereit, C. and Luft, F.C.
FASEB Journal 15 : 1822-1824. 1 January 2001

Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes.
Mervaala, E.M.A., Cheng, Z.J., Tikkanen, I., Lapatto, R., Nurminen, K., Vapaatalo, H., Mueller, D.N., Fiebeler, A., Ganten, U., Ganten, D. and Luft, F.C.
Hypertension 37 (2): 414-418. 1 January 2001

Expression analysis using oligonucleotide microarrays in mice lacking bradykinin type 2 receptors.
Monti, J., Gross, V., Luft, F.C., Milia, A.F., Schulz, H., Dietz, R., Sharma, A.M. and Hübner, N.
Hypertension 38 (1): E1-E3. 1 January 2001

Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN).
Monti, J., Schinke, M., Boehm, M., Ganten, D., Bader, M. and Bricca, G.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 280 (1): R233-R240. 1 January 2001

Induction of hippocampal glial cells expressing basic fibroblast growth factor RNA by corticosterone.
Hansson, A.C., Sommer, W., Andbjer, B., Bader, M., Ganten, D. and Fuxe, K.
NeuroReport 12 (1): 141-145. 1 January 2001

Molekularmedizinische Grundlagen von Endokrinopathien.
Ganten, D., Ruckpaul, K., Janssen, O.E. and Heufelder, A.E.
Molekulare Medizin . Springer, Berlin [u.a.]. ISBN 3-540-67788-7 1 January 2001

Molekularmedizinische Grundlagen von heriditaeren Tumorerkrankungen.
Ganten, D. and Ruckpaul, K.
Molekulare Medizin, Handbuch der Molekularen Medizin ; 9 . Springer, Berlin [u.a.]. ISBN 3-540-67808-5 1 January 2001

Naturwissenschaft und Medizin - Interdisziplinaritaet des Denkens und der Strukturen.
Ganten, D.
In: Innere Medizin am Uebergang in das 3. Jahrtausend. 26. Symposium der Gesellschaft fuer Fortschritte in der Inneren Medizin. Schriftenreihe der Gesellschaft fuer Fortschritte in der Inneren Medizin . Thieme, Stuttgart; New York, 51-55. ISBN 3-13-105841-2 1 January 2001

Overexpression of the human angiotensin II type 1 receptor in the rat heart augments load induced cardiac hypertrophy.
Hoffmann, S., Krause, T., van Geel, P.P., Willenbrock, R., Pagel, I., Pinto, Y.M., Buikema, H., van Gilst, W.H., Lindschau, C., Paul, M., Inagami, T., Ganten, D. and Urata, H.
Journal of Molecular Medicine 79 (10): 601-608. 1 January 2001

Responses to central Na+ and ouabain are attenuated in transgenic rats deficient in brain angiotensinogen.
Huang, B.S., Ganten, D. and Leenen, F.H.H.
Hypertension 37 (2): 683-686. 1 January 2001

Sequence interpretation - Functional annotation of mouse genome sequences.
Nadeau, J.H., Balling, R., Barsh, G., Beier, D., Brown, S.D.M., Bucan, M., Camper, S., Carlson, G., Copeland, N., Eppig, J., Fletcher, C., Frankel, W.N., Ganten, D., Goldowitz, D., Goodnow, C., Guenet, J.L., Hicks, G., de Angelis, M.H., Jackson, I., Jacob, H.J., Jenkins, N., Johnson, D., Justice, M., Kay, S., Kingsley, D., Lehrach, H., Magnuson, T., Meisler, M., Poustka, A.M., Rinchik, E.M., Rossant, J., Russell, L.B., Schimenti, J., Shiroishi, T., Skarnes, W.C., Soriano, P., Stanford, W., Takahashi, J.S., Wurst, W. and Zimmer, A.
Science 291 : 1251-1255. 1 January 2001

Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research.
Bader, M., Peters, J., Baltatu, O., Mueller, D.N., Luft, F.C. and Ganten, D.
Journal of Molecular Medicine 79 (2): 76-102. 1 January 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 78 (11): 592-593. January 2001

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 78 (12): 661-662. 2001

Woher kommt der Mensch? Wo steht der Mensch? Wohin geht der Mensch?
Ganten, D.
Humboldt-Spektrum 2001 (3-4): 6-9. 2001

2000

Monocyte chemoattractant protein-1 and macrophage infiltration in hypertensive kidney injury.
Hilgers, K.F., Hartner, A., Porst, M., Mai, M., Wittmann, M., Hugo, C., Ganten, D., Geiger, H., Veelken, R. and Mann, J.F.E.
Kidney International 58 : 2408-2419. 1 December 2000

High-throughput scanning of the rat genome using interspersed repetitive sequence-PCR markers.
Gosele, C., Hong, L., Kreitler, T., Rossmann, M., Hieke, B., Gross, U., Kramer, M., Himmelbauer, H., Bihoreau, M.T., Kwitek-Black, A.E., Twigger, S., Tonellato, P.J., Jacob, H.J., Schalkwyk, L.C., Lindpaintner, K., Ganten, D., Lehrach, H. and Knoblauch, M.
Genomics 69 (3): 287-294. 1 November 2000

Rats transgenic for human renin and human angiotensinogen as a model for gestational hypertension.
Bohlender, J., Ganten, D. and Luft, F.C.
Journal of the American Society of Nephrology 11 (11): 2056-2061. 1 November 2000

Transgenic animals in cardiovascular disease research.
Bader, M., Bohnemeier, H., Zollmann, F.S., Lockley-Jones, O.E. and Ganten, D.
Experimental Physiology 85 (6): 713-731. 1 November 2000

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 78 (9): 472. November 2000

Cerivastatin prevents angiotensin II-induced renal injury independent of blood pressure- and cholesterol-lowering effects.
Park, J.K., Mueller, D.N., Mervaala, E.M.A., Dechend, R., Fiebeler, A., Schmidt, F., Bieringer, M., Schaefer, O., Lindschau, C., Schneider, W., Ganten, D., Luft, F.C. and Haller, H.
Kidney International 58 (4): 1420-1430. 1 October 2000

Reduced cardiac hypertrophy and altered blood pressure control in transgenic rats with the human tissue kallikrein gene.
Silva, J.A., Araujo, R.C., Baltatu, O., Oliveira, S.M., Tschoepe, C., Fink, E., Hoffmann, S., Plehm, R., Chai, K.X., Chao, L., Chao, J., Ganten, D., Pesquero, J.B. and Bader, M.
FASEB Journal 14 (13): 1858-1860. 1 October 2000

JMM and medical science, past and present.
Ganten, D. and Vogt, P.K.
Journal of Molecular Medicine 78 (8): 397-399. October 2000

Purification and identification of p92, a sequence-specific nuclear factor interacting with the enhancer of the human papillomavirus type 18 (HPV 18).
Jia, W.
UNSPECIFIED thesis, UNSPECIFIED. 25 August 2000

Effect of Bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage.
Muller, D.N., Mervaala, E.M.A., Schmidt, F., Park, J.K., Dechend, R., Genersch, E., Breu, V., Loeffler, B.M., Ganten, D., Schneider, W., Haller, H. and Luft, F.C.
Hypertension 36 (2): 282-290. 1 August 2000

Gluco- and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat.
Hansson, A.C., Cintra, A., Belluardo, N., Sommer, W., Bhatnagar, M., Bader, M., Ganten, D. and Fuxe, K.
European Journal of Neuroscience 12 (8): 2918-2934. 1 August 2000

Angiotensin II (AT1) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy.
Mueller, D.N., Mervaala, E.M.A., Dechend, R., Fiebeler, A., Park, J.K., Schmidt, F., Theuer, J., Breu, V., Mackman, N., Luther, T., Schneider, W., Gulba, D., Ganten, D., Haller, H. and Luft, F.C.
American Journal of Pathology 157 : 111-122. 1 July 2000

Genetisches Wissen fuer Gesundheit und Krankheit [Genetic knowledge for health and disease].
Ganten, D. and Ruckpaul, K.
Nachrichten aus der Chemie 48 (7-8): 894-902. July 2000

Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats.
Fontes, M.A.P., Baltatu, O., Caligiorne, S.M., Campagnole-Santos, M.J., Ganten, D., Bader, M. and Santos, R.A.S.
Physiological Genomics 2 : 137-142. 27 April 2000

Distinguished scientists back Germany's DFG . .
Jahn, R., Boeck, A., Breiner, K.M., Breunig, K.D., Bujard, H., Campos-Ortega, J., Ganten, D., Grummt, I., Gruss, P., Goridis, C., Huber, R., Hoch, M., Jaeckle, H., Kahmann, R., Koch-Brandt, C., Leptin, M., Michel, H., Noegel, A., Neher, E., Nuesslein-Volhard, C., Pfanner, N., Sandhoff, K., Schoen, A., Schwille, P., Simons, K. and Zrenner, E.
Nature 404 : 922-922. 27 April 2000

Defective suppression of the aldosterone biosynthesis during stroke permissive diet in the stroke-prone phenotype of the spontaneously hypertensive rat.
Enea, I., De Paolis, P., Porcellini, A., Piras, O., Savoia, C., Russo, R., Giliberti, R., Gigante, B., Rubattu, S., Conte, G., Ganten, D. and Volpe, M.
Basic Research in Cardiology 95 (2): 84-92. 1 April 2000

New tools for the high throughput characterization of rat genomic DNA samples.
Knoblauch, M., Goesele, C., Zimdahl, H., Hieke, B., Himmelbauer, H., Schalkwyk, L., Lindpaintner, K., Ganten, D. and Lehrach, H.
Journal of Experimental Animal Science 41 (1-2): 35-37. 1 March 2000

Blood pressure-independent effects in rats with human renin and angiotensinogen genes.
Mervaalo, E., Mueller, D.N., Schmidt, F., Park, J.K., Gross, V., Bader, M., Breu, V., Ganten, D., Haller, H. and Luft, F.C.
Hypertension 35 (2): 587-594. 1 February 2000

Angiotensinogen concentrations and renin clearance. Implications for blood pressure regulation.
Bohlender, J., Menard, J., Ganten, D. and Luft, F.C.
Hypertension 35 : 780-786. 1 January 2000

Assignment of the kinin receptor B1 and B2 genes (Bdkrb1 and Bdkrb2) to rat chromosome 6q3.2 by FISH and radiation hybrid mapping.
Goesele, C., Gruetzner, F., Pesquero, J.B., Silva, J.A., Junge, T., Ganten, D., Bader, M. and Knoblauch, M.
Cytogenetics and Cell Genetics 89 (1-2): 51-52. 1 January 2000

Campus Berlin-Buch.
Ganten, D.
In: Das Neue Berlin : Perspektiven fuer das 21. Jahrhundert. Monographien deutscher Wirtschaftsgebiete . Kommunikation u. Wirtschaft, Oldenburg, 96-101. ISBN 3-88363-186-8 1 January 2000

Comment on "the prickly pear".
Ganten, D.
Journal of Molecular Medicine 78 (8): 403. 1 January 2000

Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes.
Mervaala, E., Mueller, D.N., Park, J.K., Dechend, R., Schmidt, F., Fiebeler, A., Bieringer, M., Breu, V., Ganten, D., Haller, H. and Luft, F.C.
Hypertension 35 (1): 360-366. 1 January 2000

Entdeckung und Erfindung : Genomforschung in Deutschland: zu wenig Geld, unsichere Rechtslage.
Ganten, D.
Berliner Republik 4 : 7-9. 1 January 2000

JMM, past and present.
Ganten, D.
Journal of Molecular Medicine 78 (10): 541-542. 1 January 2000

Monogen bedingte Erbkrankheiten 1.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 6 . Springer, Berlin [u.a.]. ISBN 3-540-65529-8 1 January 2000

Monogen bedingte Erbkrankheiten 2.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 7 . Springer, Berlin [u.a.]. ISBN 3-540-65530-1 1 January 2000

NF-kappaB Inhibition Ameliorates Angiotensin II-Induced Inflammatory Damage in Rats.
Muller, D.N., Dechend, R., Mervaala, E.M.A., Park, J.K., Schmidt, F., Fiebeler, A., Theuer, J., Breu, V., Ganten, D., Haller, H. and Luft, F.C.
Hypertension 35 (1): 193-201. 1 January 2000

Regulation of renin: new evidence from cultured cells and genetically modified mice.
Bader, M. and Ganten, D.
Journal of Molecular Medicine 78 (3): 130-139. 1 January 2000

The brain renin-angiotensin system modulates angiotensin II-induced hypertension and cardiac hypertrophy.
Baltatu, O., Silva, J.A., Ganten, D. and Bader, M.
Hypertension 35 (1): 409-412. 1 January 2000

1999

Myokardiale Dysfunktion in transgenen Ratten mit Humanrenin-induzierter arterieller Hypertonie: Phaenotypische Charakteristiken und pathogenetische Ursachen.
Hildenbrand, U.
UNSPECIFIED thesis, UNSPECIFIED. 25 December 1999

The central renin angiotensin system in blood pressure regulation: Examinations in transgenic rat strains TGR(mRen2)27 and TGR(ASrAOGEN) [Das zentrale Renin-Angiotensin-System in der Regulation des Blutdruckes: Untersuchungen an transgenen Ratten TGR(mRen2)27 und TGR(ASrAOGEN)].
Monti, J.
UNSPECIFIED thesis, UNSPECIFIED. 25 December 1999

Differential brain atrial natriuretic peptide expression co-segregates with occurrence of early stroke in the stroke-prone phenotype of the spontaneously hypertensive rat.
Rubattu, S., Giliberti, R., Ganten, U. and Volpe, M.
Journal of Hypertension 17 (12 Pt 2): 1849-1852. December 1999

Hemodynamics and metabolism in stroke-prone spontaneously hypertensive rats before manifestation of brain infarcts.
Mies, G., Hermann, D., Ganten, U. and Hossmann, K.A.
Journal of Cerebral Blood Flow and Metabolism 19 (11): 1238-1246. November 1999

Enhanced blood pressure buffering role of the brain nitrergic system in renin transgenic rats.
Lon, S., Szczepanska-Sadowska, E., Paczwa, P. and Ganten, D.
Brain Research 842 : 384-391. 25 September 1999

Angiotensin-converting enzyme inhibition and AT1 receptor blockade modify the pressure-natriuresis relationship by additive mechanisms in rats with human renin and angiotensinogen genes.
Mervaala, E., Dehmel, B., Gross, V., Lippoldt, A., Bohlender, J., Milia, A.F., Ganten, D. and Luft, F.C.
Journal of the American Society of Nephrology 10 : 1669-1680. 1 August 1999

Online first publication.
Ganten, D. and Lange, R.
Journal of Molecular Medicine 77 : 455. 1 June 1999

Role of central AT1 and V1 receptors in cardiovascular adaptation to hemorrhage in SD and renin TGR rats.
Paczwa, P., Szczepanska-Sadowska, E., Lont, S., Ganten, U. and Ganten, D.
American Journal of Physiology Heart and Circulatory Physiology 45 : H1918-H1926. 1 June 1999

Interstrain differences in angiotensin I-converting enzyme mRNA and activity levels. Comparison between stroke-prone spontaneously hypertensive rats and Wistar-Kyoto rats.
Costerousse, O., Lindpaintner, K., Paul, M., Ganten, D. and Kreutz, R.
Clinical and Experimental Hypertension 21 : 377-393. 1 May 1999

Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen.
Schinke, M., Baltatu, O., Boehm, M., Peters, J., Rascher, W., Bricca, G., Lippoldt, A., Ganten, D. and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 96 : 3975-3980. 30 March 1999

Angiotensin II AT1-receptor blockade inhibits monocyte activation and adherence in transgenic (mRen2)27 rats.
Strawn, W.B., Gallagher, P.E., Tallant, E.A., Ganten, D. and Ferrario, C.M.
Journal of Cardiovascular Pharmacology 33 : 341-351. 1 March 1999

Increased central angiotensin and osmotic responses in the Ren-2 transgenic rat.
Nishioka, T., Callahan, M.F., Li, P., Ferrario, C.M., Ganten, D. and Morris, M.
Hypertension 33 : 385-388. 11 January 1999

A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat.
Steen, R.G., Kwitek-Black, A.E., Glenn, C., Gullings-Handley, J., Van Etten, W., Atkinson, O.S., Appel, D., Twigger, S., Muir, M., Mull, T., Granados, M., Kissebah, M., Russo, K., Crane, R., Popp, M., Peden, M., Matise, T., Brown, D.M., Lu, J., Kingsmore, S., Tonellato, P.J., Rozen, S., Slonim, D., Young, P., Knoblauch, M., Provoost, A., Ganten, D., Colman, S.D., Rothberg, J., Lander, E.S. and Jacob, H.J.
Genome Research 9 : 1-8. 1 January 1999

Ausgewaehlte monogen bedingte Erkrankungen. Teil 1.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 6 . Springer, Berlin [u.a.]. 1 January 1999

Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1.
Hübner, N., Lee, Y.A., Lindpaintner, K., Ganten, D. and Kreutz, R.
Hypertension 34 : 643-648. 1 January 1999

Endothelial dysfunction in the aorta of transgenic rats harboring the mouse Ren-2 gene.
Arnet, U.A., Novosel, D., Barton, M., Noll, G., Ganten, D. and Luescher, T.F.
Endothelium 6 : 175-184. 1 January 1999

Erkrankungen des Zentralnervensystems.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 5 . Springer, Berlin [u.a.]. ISBN 3-540-64552-7 1 January 1999

Gene, Neurone, Qubits & Co : Unsere Welten der Information.
Ganten, D., Meyer-Galow, E., Ropers, H.H., Scheich, H., Schwarz, H., Urban, K. and Truscheit, E.
Verhandlungen der Gesellschaft Deutscher Naturforscher und aerzte ; 120 . Hirzel, Stuttgart. 1 January 1999

Genetica dell'ipertensione arteriosa.
Endeman, D., Paul, M. and Ganten, D.
Enciclopedia Medica Italiana 2 : 2887-2897. 1 January 1999

Hypertension-induced end-organ damage - A new transgenic approach to an old problem.
Luft, F.C., Mervaala, E., Mueller, D.N., Gross, V., Schmidt, F., Park, J.K., Schmitz, C., Lippoldt, A., Breu, V., Dechend, R., Dragun, D., Schneider, W., Ganten, D. and Haller, H.
Hypertension 33 : 212-218. 1 January 1999

Immunsystem und Infektiologie.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 4 . Springer, Berlin [u.a.]. ISBN 3-540-62464-3 1 January 1999

Monocyte infiltration and adhesion molecules in a rat model of high human renin hypertension.
Mervaala, E.M.A., Mueller, D.N., Park, J.K., Schmidt, F., Loehn, M., Breu, V., Dragun, D., Ganten, D., Haller, H. and Luft, F.C.
Hypertension 33 : 389-395. 1 January 1999

Role of chromosome X in the Sabra rat model of salt-sensitive hypertension.
Yagil, C., Sapojnikov, M., Kreutz, R., Zuercher, H., Ganten, D. and Yagil, Y.
Hypertension 33 : 261-265. 1 January 1999

Transcriptional regulation of the rat renin gene by regulatory elements in intron I.
Voigtlaender, T., Ganten, D. and Bader, M.
Hypertension 33 : 303-311. 1 January 1999

Unsere Welten der Information : eine Einfuehrung.
Ganten, D.
In: Gene, Neurone, Qubits & Co. : Unsere Welten der Information. Verhandlungen der Gesellschaft Deutscher Naturforscher und Aerzte ; 120 . Hirzel, Stuttgart, 7-13. 1 January 1999

Report on rat chromosome 10.
Knoblauch, M., Jacob, H., Ganten, D. and Lindpaintner, K.
Journal of Experimental Animal Science 40 (1-3): 81-92. 1999

1998

Pressure-natriuresis and -diuresis in transgenic rats harboring both human renin and human angiotensinogen genes.
Dehmel, B., Mervaala, E., Lippoldt, A., Gross, V., Bohlender, J., Ganten, D. and Luft, F.C.
Journal of the American Society of Nephrology 9 (12): 2212-2222. December 1998

Dual pathway for angiotensin II formation in human internal mammary arteries.
Voors, A.A., Pinto, Y.M., Buikema, H., Urata, H., Oosterga, M., Roos, G., Grandjean, J.G., Ganten, D. and van Gilst, W.H.
British Journal of Pharmacology 125 : 1028-1032. 1 November 1998

Functional evidence for alternative ANG II-forming pathways in hamster cardiovascular system.
Nishimura, H., Buikema, H., Baltatu, O., Ganten, D. and Urata, H.
American Journal of Physiology 275 : H1307-H1312. 1 October 1998

Increased pressor function of central vasopressinergic system in hypertensive renin transgenic rats.
Szczepanska-Sadowska, E., Paczwa, P., Lon, S. and Ganten, D.
Journal of Hypertension 16 : 1505-1514. 1 October 1998

Converting enzyme determines plasma clearance of angiotensin-(1-7).
Yamada, K., Iyer, S.N., Chappell, M.C., Ganten, D. and Ferrario, C.M.
Hypertension 32 (3): 496-502. 1 September 1998

Lessons from rat models of hypertension: from Goldblatt to genetic engineering.
Pinto, Y.M., Paul, M. and Ganten, D.
Cardiovascular Research 39 (1): 77-88. 1 July 1998

Local angiotensin II generation in the rat heart: role of renin uptake.
Müller, D.N., Fischli, W., Clozel, J.P., Hilgers, K.F., Bohlender, J., Menard, J., Busjahn, A., Ganten, D. and Luft, F.C.
Circulation Research 82 (1): 13-20. 9 January 1998

A transgenic rat model for Alzheimer's disease.
Ganten, D.
In: Human Genome Analysis. IOS Press, Amsterdam, 450-457. 1 January 1998

Adrenal renin expression and its role in ren-2 transgenic rats TCR(mREN2)27.
Peters, J. and Ganten, D.
Hormone and Metabolic Research 30 : 350-354. 1 January 1998

Adrenal, kidney, and heart angiotensins in female murine Ren-2 transfected hypertensive rats.
Senanayake, P.D., Smeby, R.R., Martins, A.S., Moriguchi, A., Kumagai, H., Ganten, D. and Brosnihan, K.B.
Peptides 19 : 1685-1694. 1 January 1998

Alternative splicing of the mRNA coding for the human endothelial angiotensin-converting enzyme: a new mechanism for solubilization.
Sugimura, K., Tian, X.L., Hoffmann, S., Ganten, D. and Bader, M.
Biochemical and Biophysical Research Communications 247 : 466-472. 1 January 1998

Aspekte der somatischen Gentherapie in der Herz- und Kreislaufmedizin.
von Harsdorf, R. and Dietz, R.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 37-60. 1 January 1998

Bedeutung peptiderger Systeme bei der Genese kardiovaskulaerer Erkrankungen.
Stula, M., Schott, E. and Paul, M.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 372-400. 1 January 1998

Blick nach vorn. Ein Interview.
Ganten, D.
Gegenworte Zeitschrift fuer den Disput ueber Wissen 2 : 8-11. 1 January 1998

Cardiovascular, endocrine and body fluid-electrolyte responses to salt loading in mRen-2 transgenic rats.
Li, P., Morris, M., Ferrario, C.M., Barrett, C., Ganten, D. and Callahan, M.F.
American Journal of Physiology Heart and Circulatory Physiology 44 : H1130-H1137. 1 January 1998

Changes of blood pressure and aortic strip contractile responses to ET-1 of heterozygous female transgenic rats, TGR(mRen2)27.
Cargnelli, G., Rossi, G.P., Pessina, A.C., Luciani, S., Debetto, P., Ganten, D., Peters, J. and Bova, S.
Pharmacological Research 37 : 207-211. 1 January 1998

Das "Wie" und "Wozu" der klinischen Forschung.
Ganten, D.
Forum Deutsche Krebsgesellschaft eV 13 : 21-22. 1 January 1998

Depressor role of angiotensin AT2 receptors in the (mRen-2)27 transgenic rat.
Nishioka, T., Morris, M., Li, P., Ganten, D., Ferrario, C.M. and Callahan, M.F.
American Journal of Hypertension 11 : 357-362. 1 January 1998

Editorial.
Ganten, D.
Nieren- und Hochdruckkrankheiten 27 : 104-106. 1 January 1998

Effects of AT1 receptor blockade on blood pressure and the renin-angiotensin system in spontaneously hypertensive rats of the stroke prone strain.
Wagner, J., Drab, M., Bohlender, J., Amann, K., Wienen, W. and Ganten, D.
Clinical and Experimental Hypertension 20 : 205-221. 1 January 1998

Evaluation von Gesundheitsforschung - eine methodische Uebersicht: Projekte, Foerderschwerpunkte, Einrichtungen, Innovationspotential, Effizienz, Qualitaet.
Selbmann, H.K. and Ganten, D.
[s.n.], Bonn. 1 January 1998

Functional testing of components of the brain renin-angiotensin system in transgenic animals.
Baltatu, O., Bader, M. and Ganten, D.
In: Renin-angiotensin : Proceedings from a Symposium held at the Wenner-Gren Research Institute, Stockholm, in September 1997, honouring Robert Tigerstedt and his Discovery of the Renin-angiotensin System. Wenner-Gren International Series ; 74 . Portland, London, 105-114. ISBN 1-85578-128-X 1 January 1998

Genetische Ursachen der Hypercholesterinaemie und ihre Verknuepfung mit Gefaesserkrankungen.
Schuster, H.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 325-343. 1 January 1998

Herz-Kreislauf-Erkrankungen.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.]. ISBN 3-540-62462-7 1 January 1998

Impaired vasorelaxant responses to natriuretic peptides in the stroke-prone phenotype of spontaneously hypertensive rats.
Russo, R., Vecchione, C., Cosentino, F., Natale, A., Mele, A.F., Muscolo, M., Savoia, C., Ganten, D., Rubattu, S. and Volpe, M.
Journal of Hypertension 16 : 151-156. 1 January 1998

Local renin-angiotensin system in the pineal gland.
Baltatu, O., Lippoldt, A., Hansson, A., Ganten, D. and Bader, M.
Molecular Brain Research 54 : 237-242. 1 January 1998

Mapping of candidate genes for hypertension by fluorescence in situ hybridization on the genome of transgenic rats and mice.
Schmidt, C., Ganten, D., Klenk, A. and Buselmaier, W.
Clinical and Experimental Hypertension 20 : 185-204. 1 January 1998

Mechanismen der Angiogenese.
Haller, H., Genersch, E., Lenz, T. and Luft, F.C.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 308-321. 1 January 1998

Mechanismen der Entstehung genetisch bedingter Krebsformen.
Scherneck, S. and Koelble, K.
In: Tumorerkrankungen. Handbuch der Molekularen Medizin ; 2 . Springer, Berlin [u.a.], 3-26. 1 January 1998

Molekularbiologie, Klinik und Therapie steroidbedingter Hypertonien.
Peters, J., Hampf, M., Peters, B. and Bernhardt, R.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 413-452. 1 January 1998

Molekulare Grundlagen des Gentransfers und Anwendung fuer die Gentherapie.
Brand, K. and Strauss, M.
In: Tumorerkrankungen. Handbuch der Molekularen Medizin ; 2 . Springer, Berlin [u.a.], 110-145. 1 January 1998

Molekulare Mechanismen der zentralen Regulation von Herz-Kreislauf-Funktionen und klinisch-therapeutische Aspekte.
Lippoldt, A. and Monti, J.
In: Herz-Kreislauf-Erkrankungen. Handbuch der Molekularen Medizin ; 3 . Springer, Berlin [u.a.], 3-36. 1 January 1998

Mouse and rat plasma renin concentration and gene expression in (mRen2)27 transgenic rats.
Bohlender, J., Menard, J., Edling, O., Ganten, D. and Luft, F.C.
American Journal of Physiology Heart and Circulatory Physiology 43 : H1450-H1456. 1 January 1998

NK1 receptor antagonist blocks angiotensin II responses in renin transgenic rat medulla oblongata.
Diz, D.I., Westwood, B., Bosch, S.M., Ganten, D. and Ferrario, C.M.
Hypertension 31 : 473-479. 1 January 1998

Salt susceptibility maps to chromosomes 1 and 17 with sex specificity in the Sabra rat model of hypertension.
Yagil, C., Sapojnikov, M., Kreutz, R., Katni, G., Lindpaintner, K., Ganten, D. and Yagil, Y.
Hypertension 31 : 119-124. 1 January 1998

Sustained long-term potentiation and anxiety in mice lacking the Mas protooncogene.
Walther, T., Balschun, D., Voigt, J.P., Fink, H., Zuschratter, W., Birchmeier, C., Ganten, D. and Bader, M.
Journal of Biological Chemistry 273 : 11867-11873. 1 January 1998

Transgene Tiere - ihre Nutzung in der Humanmedizin.
Ganten, D.
In: Gene und Klone. Moeglichkeiten sowie ethische Grenzen der Bio- und Gentechnologie bei Tieren. (Tagung fuer Fachleute aus Tiermedizin, Tierzucht, Rechtswissenschaft und Ethik. Besonders aber auch fuer Sonst im Tierschutz Engagierte vom 15. bis 17. Mai 1998. Protokolldienst / Evangelische Akademie Bad Boll; 98,20 . Evangelische Akademie Bad Boll, Bad Boll, 58-64. 1 January 1998

Tumorerkrankungen.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 2 . Springer, Berlin [u.a.]. ISBN 3-540-62463-5 1 January 1998

1997

Estrogen protects transgenic hypertensive rats by shifting the vasoconstrictor-vasodilator balance of RAS.
Brosnihan, K.B., Li, P., Ganten, D. and Ferrario, C.M.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 273 (6 Pt 2): R1908-R1915. 1 December 1997

Enalapril and renal function in hypertensive rats transgenic for mouse renin gene.
Springate, J.E., Feld, L.G. and Ganten, D.
Hypertension 30 : 868-872. 1 October 1997

Tissue and development specific expression of multiple alternatively spliced transcripts of rat neuronal nitric oxide synthase.
Lee, M.A., Cai, L., Hübner, N., Lee, Y.A. and Lindpaintner, K.
Journal of Clinical Investigation 100 (6): 1507-1512. 15 September 1997

Evidence for primary genetic determination of heart rate regulation. Chromosomal mapping of a genetic locus in the rat.
Kreutz, R., Stock, P., Struk, B., Hübner, N., Ganten, D. and Lindpaintner, K.
Circulation 96 (4): 1078-1081. 19 August 1997

Actions of angiotensin and lisinopril on thalamic somatosensory neurons in normotensive, non-transgenic and hypertensive, transgenic rats.
Albrecht, D., Henklein, P. and Ganten, D.
Journal of Hypertension 15 : 1151-1157. 1 January 1997

Antimetaboliten.
Matthes, E. and Langen, P.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 266-301. 1 January 1997

Brain angiotensins in the cardiovascular regulation: usefulness of transgenic animals.
Bricca, G., Schinke, M., Boehm, M., Monti, J., Hof, H., Ganten, D. and Bader, M.
Fundamental & Clinical Pharmacology 11, Suppl.1 : 53s-57s. 1 January 1997

Cardiac angiotensin II receptors: studies on functional coupling in Sprague Dawley rats and TGR(aMHC-hAT1) transgenic rats.
Rosenkranz, S., Nickenig, G., Flesch, M., Cremers, B., Schnabel, P., Lenz, O., Krause, T., Ganten, D., Hoffmann, S. and Boehm, M.
European Journal of Pharmacology - Molecular Pharmacology Section 330 : 35-46. 1 January 1997

Chronic estrogen treatment in female transgenic (mRen2)27 hypertensive rats augments endothelium-derived nitric oxide release.
Li, P., Ferrario, C.M., Ganten, D. and Brosnihan, K.B.
American Journal of Hypertension 10 : 662-670. 1 January 1997

Die Ethikkommission im Universitaetstsklinikum Benjamin Franklin.
Ganten, D. and Koellwitz, A.A.
Magazin fuer Pflegepersonal am Universitaetsklinikum Benjamin Franklin 25 : 9-10. 1 January 1997

Dose effects of human renin in rats transgenic for human angiotensiogen.
Bohlender, J., Menard, J., Luft, F.C. and Ganten, D.
Hypertension 291 : 1031-1038. 1 January 1997

Enalapril and pressure-diuresis in hypertensive rats transgenic for mouse renin gene.
Springate, J., Vanliew, J. and Ganten, D.
Kidney and Blood Pressure Research 20 : 1-5. 1 January 1997

Endothelial injury in transgenic (mRen-2)27 hypertensive rats.
Strawn, W.B., Gallagher, P., Dean, R.H., Ganten, D. and Ferrario, C.M.
American Journal of Hypertension 10 : 51-57. 1 January 1997

Endothelial vasoconstrictor of prostanoids modulate contractions to acetylcholine and ANG II in REN-2 rats.
Noll, G., Lang, M., Tschudi, M.R., Ganten, D. and Luescher, T.F.
American Journal of Physiology Heart and Circulatory Physiology 272 : H493-H500. 1 January 1997

Enzym- und Proteinanalytik.
Westermann, P.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 109-144. 1 January 1997

Genomanalyse und Gendiagnostik.
Hanke, J., Solinas-Toldo, S. and Hoheisel, J.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 51-91. 1 January 1997

Grundlagen der molekularen Zellbiologie.
Bader, M.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 3-50. 1 January 1997

High human renin hypertension in transgenic rats.
Bohlender, J., Fukamizu, A., Lippoldt, A., Nomura, T., Dietz, R., Menard, J., Murakami, K., Luft, F.C. and Ganten, D.
Hypertension 29 (1 Pt 2): 428-434. 1 January 1997

High levels of human chymase expression in the pineal and pituitary glands.
Baltatu, O., Nishimura, H., Hoffmann, S., Stoltenburg, G., Haulica, I.D., Lippoldt, A., Ganten, D. and Urata, H.
Brain Research 752 : 269-278. 1 January 1997

Hypertonie.
Ganten, D. and Bohlender, J.
In: Herz-Kreislaufforschung in Deutschland. Kohlhammer, Stuttgart, Berlin, Koeln, 177-185. 1 January 1997

Hypothalamic substance P release: attenuated angiotensin responses in mRen2(27) transgenic rats.
Diz, D.I., Falgui, B., Bosch, S.M., Westwood, B., Kent, J., Ganten, D. and Ferrario, C.M.
Hypertension 29 : 510-513. 1 January 1997

Increased potency of neuropeptide y to antagonize alpha2- adrenoceptor function in the nucleus tractus solitarii of the spontaneously hypertensive rat.
Yang, S.N., Fior, D.R., Hansson, A., Cintra, A., Castellano, M., Ganten, U., Ganten, D., Agnati, L.F. and Fuxe, K.
Neuroscience 78 : 803-813. 1 January 1997

Inhibition of brain renin-angiotensin-system by triple-helix-forming oligonucleotides is associated with modulation of blood pressure power spectrum in rats.
Monti, J., Voss, A., Schinke, M., Boehm, M., Hoff, H., Bader, M., Ganten, D. and Bricca, G.
Fundamental & Clinical Pharmacology 11 Suppl. 1 : S116. 1 January 1997

James D. Watson at the Congress of Molecular Medicine.
Ganten, D.
Journal of Molecular Medicine 75 : 615-617. 1 January 1997

Localization of angiotensin II AT1 receptor like immunoreactivity in catecholaminergic neurons of the rat medulla oblongata.
Yang, S.N., Lippoldt, A., Jansson, A., Phillips, M.I., Ganten, D. and Fuxe, K.
Neuroscience 81 : 503-515. 1 January 1997

Molekular- und zellbiologische Grundlagen.
Ganten, D and Ruckpaul, K, eds.
Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.]. ISBN 3-540-61954-2 1 January 1997

Praktische Umsetzung des Gentechnikrechts in der Forschung.
Moehring, R.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 389-413. 1 January 1997

Progression of renal failure after subtotal nephrectomy in transgenic rats carrying an additional renin gene [TGR(mREN2)27].
Wagner, J., Klotz, S., Haufe, C.C., Danser, J.A.H., Amann, K., Ganten, D. and Ritz, E.
Journal of Hypertension 15 : 441-449. 1 January 1997

Rat embryonic stem cells: a progress report.
Brenin, D.R., Look, J., Bader, M., Hübner, N., Levan, G. and Iannaccone, P.
Transplantation Proceedings 29 : 1761-1765. 1 January 1997

Renovascular hypertension with low-to-normal plasma renin: clinical and angiographic features.
Rossi, G.P., Pavan, E., Chiesura-Corona, M., Bader, M., Paganini, G., Cesari, M., De Toni, R., Feltrin, G.P., Ganten, D. and Pessina, A.C.
Clinical Science 93 : 435-443. 1 January 1997

Role of the alpha, beta, and gamma subunits of epithelial sodium channel in a model of polygenic hypertension.
Kreutz, R., Struk, B., Rubattu, S., Hübner, N., Szpirer, J., Szpirer, C., Ganten, D. and Lindpaintner, K.
Hypertension 29 : 131-136. 1 January 1997

The stroke-prone spontaneously hypertensive rat and its role in the genetic dissection of cardiovascular disease.
Hübner, N., Lee, Y.A., Kreutz, R., Lindpaintner, K. and Ganten, D.
In: Nutrition and Stroke. Nestle Nutrition Workshop Series, Supplement . Nestec Ltd., Vevey/Lippincott-Raven Publ., Philadelphia, 87-99. 1 January 1997

Tiermodelle in der biomedizinischen Forschung.
Birchmeier, C., Bladt, F. and Britsch, S.
In: Molekular- und Zellbiologische Grundlagen. Handbuch der Molekularen Medizin ; 1 . Springer, Berlin [u.a.], 338-358. 1 January 1997

Wir brauchen Frische im Geist, Ideen und wirkliches Wollen.
Ganten, D.
Biospektrum 5 : 17-18. 1 January 1997

Worse than pulp fiction: fraud in science.
Ganten, D.
Journal of Molecular Medicine 75 : 689-691. 1 January 1997

1996

Contribution of local renin angiotensin system to cardiac hypertrophy, phenotypic modulation, and remodeling in TGR(mRen2)27 transgenic rats.
Ohta, K., Kim, S.K., Wanibuchi, H., Ganten, D. and Iwao, H.
Circulation 94 (4): 785-791. 15 August 1996

Association and cosegregation of stroke with impaired edothelium-dependent vasorelaxation in stroke prone, spontaneously hypertensive rats.
Volpe, M., Iaccarino, G., Vecchione, C., Rizzoni, D., Russo, R., Rubattu, S., Condorelli, G., Ganten, U., Ganten, D., Trimarco, B. and Lindpaintner, K.
Journal of Clinical Investigation 98 (2): 256-261. 15 July 1996

Chymase- dependent angiotensin II forming system in humans.
Urata, H., Nishimura, H. and Ganten, D.
American Journal of Hypertension 9 (3): 277-284. 1 March 1996

Demonstration of renin mRNA, angiotensinogen mRNA, and angiotensin converting enzyme mRNA expression in the human eye: evidence for an intraocular renin- angiotensin system.
Wagner, J., Danser, A.H.J., Derkx, F.H.M., Dejong, P.T.V.M., Paul, M., Mullins, J.J., Schalekamp, M.A.D.H. and Ganten, D.
British Journal of Ophthalmology 80 (2): 159-163. 1 February 1996

10 years WHL: from its foundation to the world conference on hypertension control: welcome speech.
Ganten, D.
Journal of Human Hypertension 10 Suppl. : U12-U13. 1 January 1996

Angiotensin I converting enzyme and chymase in cardiovascular tissues.
Nishimura, H., Hoffmann, S., Baltatu, O., Sugimura, K., Ganten, D. and Urata, H.
Kidney International 49,Suppl.55 : S18-S23. 1 January 1996

Angiotensin-converting enzyme-independent pathways of angiotensin II formation in human tissues and cardiovascular diseases.
Urata, H., Nishimura, H., Ganten, D. and Arakawa, K.
Blood Pressure 5, Suppl.2 : 22-28. 1 January 1996

Angiotensinogen gene M235T polymorphism is not associated with diabetic nephropathy.
Schmidt, S., Giessel, R., Bergis, K.H., Strojek, K., Grzeszcak, W., Ganten, D., Ritz, E., Willms, B.H.L., Petzold, R., Henrichs, H.R., Rambausek, M., Schwarzbek, A., Schneider, P. and Bosch, A.
Nephrology Dialysis Transplantation 11 : 1755-1761. 1 January 1996

Angiotensinogen messenger RNA stabilization by angiotensin II.
Klett, C., Printz, M.P., Bader, M., Ganten, D. and Eggena, P.
Journal of Hypertension 14, Suppl.4 : S25-S36. 1 January 1996

Basic fibroblast growth factor expression and tenascin C immunoreactivity after partial unilateral hemitransection of the rat brain.
Lippoldt, A., Andbjer, B., Gerst, H., Ganten, D. and Fuxe, K.
Brain Research 730 : 1-16. 1 January 1996

Cardiorenal consequences of dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibition in transgenic rats with an extra renin gene.
Wegner, M., Hirth-Dietrich, C., Knorr, A., Dressel, J., Ganten, D. and Stasch, J.P.
Hypertension Research 19 : 151-159. 1 January 1996

Chromosomal mapping of quantitative trait loci contributing to stroke in a rat model of complex human disease.
Rubattu, S., Volpe, M., Kreutz, R., Ganten, U., Ganten, D. and Lindpaintner, K.
Nature Genetics 13 : 429-434. 1 January 1996

Development, genotype and phenotype of a new colony of the Sabra hypertension prone (SBH/y) and resistant (SBN/y) rat model of salt sensitivity and resistance.
Yagil, C., Katni, G., Rubattu, S., Stolpe, C., Kreutz, R., Lindpaintner, K., Ganten, D., Ben-Ishay, D. and Yagil, Y.
Journal of Hypertension 14 : 1175-1182. 1 January 1996

Developpement chez le rat d'hypertension a la renine humaine [Development of a model of human renin-dependent hypertension in the rat].
Bohlender, J., Menard, J., Wagner, J., Luft, F.C. and Ganten, D.
Archives des Maladies du Coeur et des Vaisseaux 89 : 1009-1011. 1 January 1996

Effect of losartan on right ventricular hypertrophy and cardiac angiotensin I-converting enzyme activity in pulmonary hypertensive rats.
Kreutz, R., Fernandez-Alfonso, M.S., Ganten, D. and Paul, M.
Clinical and Experimental Hypertension 18 (1): 101-111. 1 January 1996

Expression of cytochrome P45011B1 mRNA in the brain of normal and hypertensive transgenic rats.
Erdmann, B., Gerst, H., Lippoldt, A., Buelow, H., Ganten, D., Fuxe, K. and Bernhardt, R.
Brain Research 733 : 73-82. 1 January 1996

Human renin-dependent hypertension in rats transgenic for human angiotensinogen.
Bohlender, J., Menard, J., Wagner, J., Luft, F.C. and Ganten, D.
Hypertension 27 : 535-540. 1 January 1996

Hypertension Control: Worldwide Experience. Proceedings of the World Conference on Hypertension Control, Ottawa, Canada, 21 - 24 June, 1995.
Chockalingam, A., Fodor, J.G., Ganten, D. and Strasser, T.
Journal of Human Hypertension, Vol. 10, Suppl. 1 . UNSPECIFIED. 1 January 1996

Hypertension control in the world: an agenda for the coming decade (the 1995 WHL Ottawa Declaration).
Sleight, P., Ganten, D., Chockalingam, A., Dodu, S., Fodor, G., Froehlich, E., Lenfant, C., Moser, M., Mulrow, P., Reddy, S., Ribeiro, A. and Strasser, T.
Journal of Human Hypertension 10 Suppl. : S1-S3. 1 January 1996

Mechanismus der Gewebe-Angiotensin-II-Bildung im Herzen und neue Befunde zum kardialen Angiotensin-II-System.
Urata, H., Hoffmann, S., Nishimura, H., Baltatu, O., Strobel, F., Krause, T. and Ganten, D.
In: Angiotensin II - Antagonismus. Ein neuer Weg zur Hochdruckbehandlung. Springer, Berlin, 30-55. 1 January 1996

Molecular cloning and functional characterization of a mouse bradykinin B1 receptor gene.
Pesquero, J.B., Pesquero, J.L., Oliveira, S.M., Roscher, A.A., Metzger, R., Ganten, D. and Bader, M.
Biochemical and Biophysical Research Communications 220 (1): 219-225. 1 January 1996

Molecular regulation of smooth muscle contraction.
Morano, I.
In: Molecular Reviews in Cardiovascular Medicine. Chapman & Hall, London [u.a.], 49-53. 1 January 1996

Molekulare Medizin: Herausforderung fuer die Klinische Pharmakologie (Editorial).
Ganten, D.
Biospektrum 2 : 4. 1 January 1996

Neutral endopeptidase inhibition potentiates the effects of natriuretic peptides in renin transgenic rats.
Wegner, M., Ganten, D. and Stasch, J.P.
Hypertension Research 19 : 229-238. 1 January 1996

Permanent inhibition of angiotensinogen synthesis by antisense RNA expression.
Schinke, M., Boehm, M., Bricca, G., Ganten, D. and Bader, M.
Hypertension 27 : 508-513. 1 January 1996

Physiological characterization of the hypertensive transgenic rat TGR(mREN2)27.
Lee, M.A., Boehm, M., Paul, M., Bader, M., Ganten, U. and Ganten, D.
American Journal of Physiology Endocrinology and Metabolism 270 : E919-E929. 1 January 1996

Programme for countering emerging infectious diseases (ProCEID) by prophylatic, diagnostic and therapeutic measures. Mission statement, revised.
Geissler, E. and Ganten, D.
Biologicals 24 : 71-74. 1 January 1996

Reduction of cardiac hypertrophy in TGR(mREN2)27 by angiotensin II receptor blockade.
Boehm, M., Lippoldt, A., Wienen, W., Ganten, D. and Bader, M.
Molecular and Cellular Biochemistry 163-164 : 217-221. 1 January 1996

Renal and antihypertensive effects of neutral endopeptidase inhibition in transgenic rats with an extra renin gene.
Stasch, J.P., Hirth-Dietrich, C., Ganten, D. and Wegner, M.
American Journal of Hypertension 9 : 795-802. 1 January 1996

Role of area postrema in transgene hypertension.
Averill, D., Matsumura, K., Ganten, D. and Ferrario, C.M.
Hypertension 27 : 591-597. 1 January 1996

Role of paraventricular angiotensin AT-1 receptors in salt sensitive hypertension in mRen-2 transgenic rats.
Li, P., Morris, M., Diz, D.I., Ferrario, C.M., Ganten, D. and Callahan, M.F.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 39 : R1178-R1181. 1 January 1996

Salt sensitive hypertension in (mREN-2)27 transgenic rats.
Callahan, M.F., Ping, L., Ferrario, C.M., Ganten, D. and Morris, M.
Hypertension 27 : 573-577. 1 January 1996

Subcellular localization of angiotensin II immunoreactivity in the rat cerebellar cortex.
Erdmann, B., Fuxe, K. and Ganten, D.
Hypertension 28 : 818-824. 1 January 1996

Synthesis and secretion of natriuretic peptides in the hypertensive TGR(mREN-2)27 transgenic rat.
Marttila, M., Vuolteenaho, O., Ganten, D., Nakao, K. and Ruskoaho, H.
Hypertension 28 : 995-1004. 1 January 1996

The hypertensive Ren-2 transgenic rat TGR(mREN2)27 in hypertension research characteristics and functional aspects.
Langheinrich, M., Lee, M.A., Boehm, M., Pinto, Y.M. and Ganten, D.
American Journal of Hypertension 9 (5): 506-512. 1 January 1996

The renin-angiotensin system and renal function in transgenic (mRen2)27 rats.
Gross, V., Lippoldt, A., Bohlender, J., Ganten, D., Ganten, U. and Luft, F.C.
Experimental Nephrology 4, Suppl.1 : 20-26. 1 January 1996

The renin-angiotensin system in transgenic rats.
Wagner, J., Thiele, F. and Ganten, D.
Pediatric Nephrology 10 (1): 108-112. 1 January 1996

Transcriptional regulatory elements in the rat bradykinin B2 receptor gene.
Pesquero, J.B., Lindsey, C.J., Paiva, A.C.M., Ganten, D. and Bader, M.
Immunopharmacology 33 : 36-41. 1 January 1996

Transgenic rats: tools to study the function of the renin-angiotensin system. Proceedings of the symposium 'angiotensin AT1 receptors: from molecular physiology to therapeutics'.
Bader, M. and Ganten, D.
Clinical and Experimental Pharmacology and Physiology Suppl.3 : S81-S87. 1 January 1996

Was kann die Medizin von der Gentechnik erwarten?
Ganten, D.
In: Wissenschaftszentrum Nordrhein-Westfalen: Jahrbuch 1995. Wissenschaftszentrum Nordrhein-Westfalen, Duesseldorf, 80-89. 1 January 1996

Molecular reviews in cardiovascular medicine.
Lindpaintner, K. and Ganten, D.
Springer, Berlin. ISBN 0-412-78260-X 1996

1995

Liposomaler Gentransfer in Nierenzellen.
Madry, H.
UNSPECIFIED thesis, UNSPECIFIED. 20 December 1995

Genetic linkage of the ACE gene to plasma angiotensin-converting enzyme activity but not to blood pressure: a quantitative trait locus confers identical complex phenotypes in human and rat hypertension.
Kreutz, R., Hübner, N., Ganten, D. and Lindpaintner, K.
Circulation 92 (9): 2381-2384. 1 November 1995

No association of converting enzyme insertion/deletion polymorphism with immunoglobulin a glomerulonephritis.
Schmidt, S., Stier, E., Hartung, R., Stein, G., Bahnisch, J., Woodroffe, A.J., Clarkson, A.R., Ponticelli, C., Campise, M., Mayer, G., Ganten, D. and Ritz, E.
American Journal of Kidney Diseases 26 (5): 727-731. 1 November 1995

Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10.
Kreutz, R., Hübner, N., James, M.R., Bihoreau, M.T., Gauguier, D., Lathrop, G.M., Ganten, D. and Lindpaintner, K.
Proceedings of the National Academy of Sciences of the United States of America 92 (19): 8778-8782. 12 September 1995

Regulation of aldosterone biosynthesis by adrenal renin is mediated through AT1 receptors in renin transgenic rats.
Volpe, M., Rubattu, S., Gigante, G., Ganten, D., Porcellini, A., Russo, R., Romano, M., Enea, I., Lee, M.A. and Trimarco, B.
Circulation Research 77 (1): 73-79. July 1995

Opposing actions of angiotensin-(1-7) and angiotensin II in the brain of transgenic hypertensive rats.
Moriguchi, A., Tallant, E.A., Matsumura, K., Reilly, T.M., Walton, H., Ganten, D. and Ferrario, C.M.
Hypertension 25 (6): 1260-1265. 1 June 1995

Angiotensin and bradykinin peptides in the TGR(mREN-2)27 rat.
Campbell, D.J., Rong, P., Kladis, A., Rees, B., Ganten, D. and Skinner, S.L.
Hypertension 25 (5): 1014-1020. 1 May 1995

Alterations of cardiac alpha- and beta-adrenoceptors and inotropic responsiveness in hypertensive transgenic rats harbouring the mouse renin gene (TGR(mREN2)27).
Tawfik-Schlieper, H., Moll, M., Schmid, B., Schwinger, R.H.G., Paul, M., Ganten, D. and Boehm, M.
Clinical and Experimental Hypertension 17 : 631-648. 1 January 1995

Altered angiotensinogen amino acid sequence and plasma angiotensin II levels in genetically hypertensive rats: a study on cause and effects.
Huebner, N., Kreutz, R., Takahashi, S., Ganten, D. and Lindpaintner, K.
Hypertension 26 : 279-284. 1 January 1995

Angiotensin II receptor blockade in TGR(mREN2)27: effects of renin-angiotensin-system gene expression and cardiovascular functions.
Boehm, M., Lee, M.A., Kreutz, R., Kim, S., Schinke, M., Djavidani, B., Wagner, J., Kaling, M., Wienen, W., Bader, M. and Ganten, D.
Journal of Hypertension 13 : 891-899. 1 January 1995

Auf dem Wege zu verbesserter klinischer Forschung.
Ganten, D. and Schnitzer-Ungefug, J.
In: Community Medicine. 1.Internationaler Workshop in Greifswald. Peter Lang, Frankfurt /Main, 169-183. ISBN 3-631-48080-6 1 January 1995

Charakterisierung der transgenen Rattenlinie TGR(mREN2)27.
Lee, M.A.
UNSPECIFIED thesis, UNSPECIFIED. 1 January 1995

Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27.
Djavidani, B., Sander, M., Kreutz, R., Zeh, K., Bader, M., Mellon, S.H., Vecsei, P., Peters, J. and Ganten, D.
Journal of Hypertension 13 (6): 637-645. 1 January 1995

Contribution of A 12 kDa protein to the angiotensin II-induced stabilization of angiotensinogen mRNA : interaction with the 3'untranslated mRNA.
Klett, C., Bader, M., Schwemmle, M., Ganten, D. and Hackenthal, E.
Journal of Molecular Endocrinology 14 : 209-226. 1 January 1995

Converting enzyme inhibitors differentially affect expression of genes of the renin-angiotensin system.
Keuneke, C., Yacullo, R., Sugiura, M., Mall, G., Metzger, R. and Ganten, D.
Clinical and Experimental Hypertension 17 (3): 551-574. 1 January 1995

Decreased renal haemodynamic response to inhibition of nitric oxide synthase in subtotally nephrectomised rats.
Wagner, J., Wystrychowski, A., Stauss, H., Ganten, D. and Ritz, E.
Pfluegers Archiv European Journal of Physiology 430 : 181-187. 1 January 1995

Diagnostik und Therapie des Bluthochdrucks.
Ganten, D.
MED-REPORT 18 (27): 4-4. 1 January 1995

Die Genetik der Hypertonie.
Ganten, D., Stolpe, C. and Lindpaintner, K.
In: Berlin-Brandenburgische Akademie der Wissenschaften : Jahrbuch 1994. Akad.Verl., Berlin, 223-231. ISBN 3-05-002774-6 1 January 1995

Die Genetik des Bluthochdrucks: Molekulare Analyse einer Volkskrankheit.
Ganten, D., Stolpe, C. and Lindpaintner, K.
In: Wissenschaft in der globalen Herausforderung. Verhandlungen der Gesellschaft Deutscher Naturforscher und Ärzte 118.Versammlung - Hamburg 1994. Wiss.Verlagsgesellschft mbH, Stuttgart, 351-364. 1 January 1995

Differential gene expression of renin and angiotensinogen in the TGR(mREN-2)27 transgenic rat.
Lee, M.A., Boehm, M., Kim, S., Bachmann, S., Bachmann, J., Bader, M. and Ganten, D.
Hypertension 25 : 570-580. 1 January 1995

Effects of human renin in the vasculature of rats transgenic for human angiotensinogen.
Mueller, D.N., Hilgers, K.F., Bohlender, J., Lippoldt, A., Wagner, J., Fischli, W., Ganten, D., Mann, J.F.E. and Luft, F.C.
Hypertension 26 : 272-278. 1 January 1995

Endothelin and experimental hypertension.
Boecker, W., Ganten, D. and Paul, M.
In: Experimental Hypertension and Therapeutic Progress: Vasodilation and Beyond. Springer, Berlin [u.a.], 1-14. ISBN 3-540-58545-1 1 January 1995

Evidence for a differential modulation of the alpha-2 adrenoreceptors by angiotensin II in the nucleus tractus solitarii of the spontaneously hypertensive and the wistar kyoto normotensive rats.
Fior, D.R., Yang, S.N., Ganten, U., Ganten, D. and Fuxe, K.
Brain Research 679 : 168-177. 1 January 1995

Expression of the mouse and rat mas proto-oncogene in the brain and peripheral tissues.
Metzger, R., Bader, M., Ludwig, T., Berberich, C., Bunnemann, B. and Ganten, D.
FEBS Letters 357 : 27-32. 1 January 1995

Gene expression of brain nitric oxide synthase and soluble guanylyl cyclase in hypothalamus and medulla of two-kidney, one clip hypertensive rats.
Krukoff, T.L., Gehlen, F., Ganten, D. and Wagner, J.
Hypertension 26 : 171-176. 1 January 1995

Genetics in arterial hypertension - clinical and experimental aspects.
Hübner, N. and Ganten, D.
Herz 20 : 309-314. 1 January 1995

Genetics of hypertension.
Lindpaintner, K., Kreutz, R. and Ganten, D.
In: Scientific American: Molecular Cardiovascular Medicine. Scientific American Inc., New York, 243-257. 1 January 1995

Genetische Analyse des Bluthochdrucks.
Lee, Y.A., Hübner, N. and Ganten, D.
In: Jahrbuch 1995 der Deutschen Akademie der Naturforscher Leopoldina (Halle/Saale). Leopoldina, R.3, 41 . Dt. Akad. d. Naturforscher Leopoldina, Halle/Saale, 323-333. 1 January 1995

Hormones, autacoids, neurotransmitters, and growth factors.
Ganten, D., Luft, F.C. and Kurokawa, K.
Current Opinion in Nephrology and Hypertension 4 : B1-B18. 1 January 1995

Increased vasopressor actions of intraventricular neuropeptide Y-(13-36) in spontaneously hypertensive versus normotensive Wistar-Kyoto rats. Possible relationship to increases in Y2 receptor binding in the nucleus tractus solitarius.
Aguirre, J.A., Hedlund, P.B., Narvaez, J.A., Bunnemann, B., Ganten, D. and Fuxe, K.
Brain Research 684 (2): 159-164. 1 January 1995

Induction of cardiac angiotensin I-converting enzyme with dietary NaCL-loading in genetically hypertensive and normotensive rats.
Kreutz, R., Fernandez-Alfonso, M.S., Liu, Y., Ganten, D. and Paul, M.
Journal of Molecular Medicine 73 (5): 243-248. 1 January 1995

Infertility in a transgenic rat due to impairment of cytoplasmic elimination and sperm release from the sertoli cells.
Sharpe, R.M., Maguire, S.M., Saunders, P.T.K., Millar, M.R., Russel, L.D., Ganten, D., Bachmann, S., Mullins, L. and Mullins, J.J.
Biology of Reproduction 53 : 214-226. 1 January 1995

Local renin-angiotensin systems in cardiovascular tissues: localization and functional role.
Stock, P., Liefeld, L., Paul, M. and Ganten, D.
Cardiology 86 (Suppl.1): 2-8. 1 January 1995

Mechanisms of angiotensin II formation in humans.
Urata, H., Nishimura, H. and Ganten, D.
European Heart Journal 16, Suppl.N : 79-85. 1 January 1995

Molecular structure of rat bradykinin B2 receptor gene.
Pesquero, J.B., Lindsey, C.J., Zeh, K., Paiva, A.C.M., Ganten, D. and Bader, M.
Nieren- und Hochdruckkrankheiten 24 : 602-604. 1 January 1995

Neurotransmitters and neuropeptides in the baroreceptor reflex arc: connections between the nucleus of the solitary tract and the ventrolateral medulla oblongata in the rat.
Palkovits, M., Mezey, E., Fodor, M., Ganten, D., Bahner, U., Geiger, H. and Heidland, A.
Clinical and Experimental Hypertension 17 : 101-113. 1 January 1995

Novel approaches towards the nuclear expression of ribozyme and antisense RNA genes in transgenic mice.
Sharp, M.G.F., Ganten, D. and Mullins, J.J.
In: Mechanisms and Applications of Gene Silencing. University Press, Nottingham, 185-194. 1 January 1995

Rodent models for studying steroids and hypertension : from fetal development to cells in culture.
Mellon, S.H., Compagnone, N., Sander, M., Cover, C., Ganten, D. and Djavidani, B.
Steroids 60 (1): 59-64. 1 January 1995

The brain renin-angiotensin system: molecular mechanisms of cell to cell interactions.
Lippoldt, A., Paul, M., Fuxe, K. and Ganten, D.
Clinical and Experimental Hypertension 17 : 251-266. 1 January 1995

The gene encoding endothelial nitric oxide synthase, Nos3, maps to rat chromosome 4.
Hübner, N., Kreutz, R., Rubattu, S., Lee, Y.A., Ganten, D., Allen, P.D. and Lindpaintner, K.
Mammalian Genome 6 (10): 758-759. 1 January 1995

The world hypertension league: goals and perspectives.
Ganten, D. and Poetzsch, J.
Clinical and Experimental Hypertension 17 (7): 1079-1089. 1 January 1995

Tradition, continuity, and renaissance.
Ganten, D.
Journal of Molecular Medicine 73 : 1-3. 1 January 1995

Transcriptional silencer in intron I of the rat renin gene.
Voigtlaender, T., Ripperger, A., Ganten, D. and Bader, M.
Advances in Experimental Medicine and Biology 377 : 285-292. 1 January 1995

Transgenic animals as models for human disease (Review).
Wagner, J., Thiele, F. and Ganten, D.
Clinical and Experimental Hypertension 17 (4): 593-605. 1 January 1995

Transgenic laboratory animals in hypertension research.
van der Giet, M., Hoffmann, S., Urata, H., Ganten, D. and Paul, M.
Scandinavian Journal of Laboratory Animal Sciences 22 (2): 205-211. 1 January 1995

Verbund Klinische Pharmakologie Berlin/Brandenburg. Gentherapie, Pharmakogenetik, Pharmakoepidemiologie.
Ganten, D., Engler, E. and Ruckpaul, K.
Klinische Pharmakologie aktuell 6 : 44-54. 1 January 1995

Vom Gen zur Therapie: Paradigmenwechsel in der Klinischen Pharmakologie.
Ganten, D.
Klinische Pharmakologie aktuell 6 : 35-36. 1 January 1995

Association of M235T variant of the angiotensinogen gene with familial hypertension of early onset.
Schmidt, S., Sharma, A.M., Zilch, O., Beige, J., Walla-Friedel, M., Ganten, D., Distler, A. and Ritz, E.
Nephrology Dialysis Transplantation 10 (7): 1145-1148. 1995

1994

Widespread tissue distribution of human chymase.
Urata, H., Strobel, F. and Ganten, D.
Journal of Hypertension 12 (Suppl.) (9): S17-S22. 1 November 1994

Augmented agonist induced Ca2+-sensitization of coronary artery contraction in genetically hypertensive rats - evidence for altered signal transduction in the coronary smooth muscle cells.
Satoh, S., Kreutz, R., Wilm, C., Ganten, D. and Pfitzer, G.
Journal of Clinical Investigation 94 (4): 1397-1403. October 1994

Unlike human hypertension, blood pressure in a hereditary hypertensive rat strain shows no linkage to the angiotensinogen locus.
Hübner, N., Kreutz, R., Takahashi, S., Ganten, D. and Lindpaintner, K.
Hypertension 23 (6 Pt 1): 797-801. 1 June 1994

Alteration in coronary artery vascular reactivity of hypertensive Ren-2 transgenic rats.
Tschudi, M.R., Noll, G., Arnet, U., Novosel, D., Ganten, D. and Luescher, T.F.
Circulation 89 (6): 2780-2786. June 1994

Mechanisms of hypertension in transgenic rats expressing the mouse Ren-2 gene.
Moriguchi, A., Brosnihan, K.B., Kumagai, H., Ganten, D. and Ferrario, C.M.
American Journal of Physiology Renal Physiology 266 (4 Pt 2): R1273-R1279. 1 April 1994

Role of adrenal renin in the regulation of adrenal steroidogenesis corticotropin.
Sander, M., Ganten, D. and Mellon, S.H.
Proceedings of the National Academy of Sciences of the United States of America 91 (1): 148-152. 4 January 1994

Activation of the renin-angiotensin system in heart failure and hypertrophy - studies in human hearts and transgenic rats.
Paul, M., Pinto, Y.M., Schunkert, H., Ganten, D. and Boehm, M.
European Heart Journal 15 (Suppl.D) : 63-67. 1 January 1994

Basic methods of molecular biology in cardiovascular research.
Paul, M., Bader, M., Wagner, J. and Ganten, D.
In: Molecular Cell Biology of Cardiovascular Diseases. Mosby, Madrid [u.a.], 41-48. 1 January 1994

Biesenthal consensus: Biesenthal vaccine initiative (Vaccines for peace).
Calderon, F., Drozdov, S.G., Fenner, F., Ganten, D., Geissler, E., Horoud, F., Kane, M., L'age-Stehr, J., Langen, P., Leitenberg, M., Melling, J., Morse, S.S., Netesov, S.V., Nixdorff, K., Pearson, G., Sandstroem, G., Subrahmanyam, D., Thraenert, O., Toth, T., Valette, M.L., Wheelis, M.L. and Woodall, J.P.
In: The Royal Society: Scientific of Control of Biological Weapons. Royal Society Study Group, London, 121-125. 1 January 1994

Bluthochdruck. Die beteiligten Gene und ihre Bedeutung.
Kreutz, R., Hübner, N., Ganten, D. and Lindpaintner, K.
In: Wieviel Genetik braucht der Mensch. Konstanzer Bibliothek ; 23 . Univ.-Verl., Konstanz, 239-252. 1 January 1994

Differential regulation of central vasopressin in transgenic rats harboring the mouse Ren-2 gene.
Moriguchi, A., Ferrario, C.M., Brosnihan, K.B., Ganten, D. and Morris, M.
American Journal of Physiology Renal Physiology 267 : R786-R791. 1 January 1994

Differential regulation of vascular angiotensin I-converting enzyme in hypertension.
Fernandez-Alfonso, M.S., Kreutz, R., Zeh, K., Liu, Y., Ganten, D. and Paul, M.
Hypertension 24 : 280-286. 1 January 1994

Effects of enalaprilat on circadian profiles in blood pressure and heart rate of spontaneously and transgenic hypertensive rats.
Lemmer, B., Witte, K., Makabe, T., Ganten, D. and Mattes, A.
Journal of Cardiovascular Pharmacology 23 : 311-314. 1 January 1994

Effects of nephrectomy and adrenalectomy on the renin-angiotensin system on transgenic rats TGR(mRen2)27.
Tokita, Y., Franco-Saenz, R., Mulrow, P.J. and Ganten, D.
Endocrinology 134 : 253-257. 1 January 1994

Enhanced adrenal renin and aldosterone biosynthesis during sodium restriction in TGR (mREN2)27.
Rubattu, S., Enea, I., Ganten, D., Salvatore, D., Condorelli, G.L., Condorelli, G., Russo, R., Romano, M., Gigante, B., Trimarco, B. and Volpe, M.
American Journal of Physiology Endocrinology and Metabolism 267 : E515-E520. 1 January 1994

Estrogen augments the contribution of nitric oxide to blood pressure regulation in transgenic hypertensive rats expressing the mouse Ren-2 gene.
Brosnihan, K.B., Moriguchi, A., Nakamoto, H., Dean, R.H., Ganten, D. and Ferrario, C.M.
American Journal of Hypertension 7 : 576-582. 1 January 1994

Experimental and genetic models of hypertension.
Ganten, D.
Handbook of Hypertension ; 16 . Elsevier, Amsterdam. 1 January 1994

Genetics of primary hypertension.
Schmidt, S. and Ganten, D.
Nephrology Dialysis Transplantation 9 : 473-474. 1 January 1994

Genetics of primary hypertension.
Ganten, D., Schmidt, S. and Paul, M.
Journal of Cardiovascular Pharmacology 24 : S45-S50. 1 January 1994

Human angiotensinogen if highly expressed in astrocytes in human cortical grafts.
Humpel, C., Lippoldt, A., Stroemberg, I., Bygdeman, M., Wagner, J., Hilgenfeldt, U., Ganten, D., Fuxe, K. and Olson, L.
Glia 10 : 186-192. 1 January 1994

Human heart chymase.
Husain, A., Kinoshita, A., Sung, S.S., Urata, H. and Bumpus, F.M.
In: The Cardiac Renin-Angiotensin System. Futura Medical Publ., New York, 309-331. 1 January 1994

Increase of basic fibroblast growth factor (bFGF,FGF-2) messenger RNA and protein following implantation of a microdialysis probe into rat hippocampus.
Humpel, C., Chadi, G., Lippoldt, A., Ganten, D., Fuxe, K. and Olson, L.
Experimental Brain Research 98 : 229-237. 1 January 1994

Increased cytosolic sodium and reduced Na,K-ATPase activity in transgenic rats.
Tepel, M., Theilmeier, G., Bachmann, J., Barenbrock, M., Spieker, C., Ganten, D., Rahn, K.H. and Zidek, W.
Hypertension 23, Suppl. I : I-198-I-202. 1 January 1994

Insulin resistance and hypertension: studies in transgenic hypertensive TGR(mREN-2)27 rats.
Vetter, R., Cusin, I., Ganten, D., Rohner-Jeanrenaud, F., Ferrannini, E. and Jeanrenaud, B.
American Journal of Physiology Renal Physiology 267 (6): R1503-R1509. 1 January 1994

Kraft fuer den Aufschwung. Biomedizinische Forschung in den neuen Bundeslaendern.
Ganten, D.
Wissenschaft und Wirtschaft 3 : 38-44. 1 January 1994

Mechanism by which angiotensin II stabilizes messenger RNA for angiotensinogen.
Klett, C., Bader, M., Ganten, D. and Hackenthal, E.
Hypertension 23 : I120-I125. 1 January 1994

Molecular biology and biochemistry of the renin-angiotensin system.
Bader, M., Paul, M., Fernandez-Alfonso, M.S., Kaling, M. and Ganten, D.
In: Textbook of Hypertension. Blackwell, Oxford, 214-232. 1 January 1994

Molecular mechanisms of renin expression and regulation: functional relevance for the activity of the renin angiotensin system.
Paul, M. and Ganten, D.
In: Regulation and Control of Complex Biological Processes by Biotransformation. Frontiers in Biotransformation ; 9 . Akademie Verl., Berlin, 1-59. 1 January 1994

Molecular structure and expression of rat bradykinin B2 receptor gene. Evidence for alterative splicing.
Pesquero, J.B., Lindsey, C.J., Zeh, K., Paiva, A.C.M., Ganten, D. and Bader, M.
Journal of Biological Chemistry 43 : 26920-26925. 1 January 1994

Molekulargenetische Grundlagen und Perspektiven fuer die Diagnostik und Therapie des Bluthochdrucks.
Ganten, D.
Laboratory Medicine 18 : 351-352. 1 January 1994

Neue Strategien zur Praevention und Therapie der Hypertonie (Gespraech anlaesslich des 6th European Meeting on Hypertension, Mailand 4.-7. Juni 1993).
Ganten, D.
Herz Kreislauf 26 : IV-VI. 1 January 1994

On the plasticity of the cerebellar renin-angiotensin system: Localization of components and effects of mechanical perturbation.
Lippoldt, A., Bunnemann, B., Ueki, A., Rosen, L., Cintra, A., Hasselrot, U., Metzger, R., Hilgenfeldt, U., Brosnihan, K.B., Ganten, D. and Fuxe, K.
Brain Research 668 : 144-159. 1 January 1994

PCR analysis of human renal biopsies - renin gene regulation in glomerulonephritis.
Wagner, J., Drab, M., Gehlen, F., Langheinrich, M., Volk, S., Ganten, D. and Ritz, E.
Kidney International 46 : 1542-1545. 1 January 1994

Pathophysiologie des Renin-Angiotensin-Systems.
Klett, C., Paul, M., Hackenthal, E. and Ganten, D.
In: ACE-Hemmer : Handbuch. 2., ueberarb. und erw. Aufl. Schattauer, Stuttgart [u.a.], 9-74. 1 January 1994

Renal effects of captopril and nitrendipine in transgenic rats with an extra renin gene.
Hirth-Dietrich, C., Stasch, J.P., Ganten, D. and Luft, F.C.
Hypertension 23 : 626-631. 1 January 1994

Renal function in hypertensive rats transgenic for mouse renin gene.
Springate, J.E., Feld, L.G. and Ganten, D.
American Journal of Physiology 266 : F731-F737. 1 January 1994

The Cardiac Renin-Angiotensin System.
Lindpaintner, K. and Ganten, D.
Futura Publ. Comp., Armonk. 1 January 1994

The cardiac renin-angiotensin system and human coronary physiology and pathology.
Osterziel, K.J. and Dietz, R.
In: The Cardiac Renin-Angiotensin System. Futura Publishing Company, Inc., Armonk, NY, 333-343. 1 January 1994

The human renin-angiotensin-system in transgenic rats.
Ganten, D. and Wagner, J.
In: Patenting of Human Genes and Living Organisms. Springer, Berlin, 185-196. 1 January 1994

The role of the renin-angiotensin system in cardiovascular disease.
Bader, M., Wagner, J., Lee, M.A. and Ganten, D.
Hypertension Research 17 : 1-16. 1 January 1994

Tissue angiotensin II system in the human heart.
Urata, H., Hoffmann, S. and Ganten, D.
European Heart Journal 15 (Suppl D): 68-78. 1 January 1994

Transgenic animal models for hypertension.
Paul, M., Wagner, J., Bader, M. and Ganten, D.
In: Textbook of Hypertension. Blackwell, Oxford, 469-476. 1 January 1994

Transgenic rats and experimental hypertension.
Hoffmann, S., Paul, M., Urata, H., Wagner, J. and Ganten, D.
In: Hypertension: Pathophysiology, Diagnosis, and Management. Raven Press, New York, [s.p.]. 1 January 1994

Transgenic rats expressing components of the renin-angiotensin system : focus on cardiovascular regulation.
Paul, M., Wagner, J., Kreutz, R., Fernandez-Alfonso, M.S., Liu, Y., Bader, M. and Ganten, D.
In: The Cardiac Renin-Angiotensin System. Futura Publ. Comp., Armonk, [s.p.]. 1 January 1994

Vascular angiotensin and the sympathetic nervous system: do they interact?
Hilgers, K.F., Veelken, R., Kreppner, I., Ganten, D., Luft, F.C., Geiger, H. and Mann, J.F.
American Journal of Physiology Heart and Circulatory Physiology 267 : H187-H194. 1 January 1994

Zona glomerulosa of the adrenal gland in a transgenic strain of rat: A morphologic and functional study.
Rocco, S., Rebuffat, P., Cimolato, M., Opocher, G., Peters, J., Mazzocchi, G., Ganten, D., Mantero, F. and Nussdorfer, G.G.
Cell and Tissue Research 278 : 21-28. 1 January 1994

beta-adrenergic neuroeffector mechanisms in cardiac hypertrophy of renin transgenic rats.
Boehm, M., Moll, M., Schmid, B., Paul, M., Ganten, D., Castellano, M. and Erdmann, E.
Hypertension 24 : 653-662. 1 January 1994

Increased expression of angiotensin peptides in the brain of transgenic hypertensive rats.
Senanayake, P.D., Moriguchi, A., Kumagai, H., Ganten, D., Ferrario, C.M. and Brosnihan, K.B.
Peptides 15 (5): 919-926. 1994

Transgenic rats: new experimental models for the study of candidate genes in hypertension research.
Paul, M., Wagner, J., Hoffmann, S., Urata, H. and Ganten, D.
Annual Review of Physiology 56 : 811-829. 1994

1993

Antisense oligonucleotide to c-fos induces ipsilateral rotational behaviour to d-amphetamine.
Sommer, W., Bjelke, B., Ganten, D. and Fuxe, K.
NeuroReport 5 (3): 277-280. 13 December 1993

The renin-angiotensin system in the brain: an update 1993.
Bunnemann, B., Fuxe, K. and Ganten, D.
Regulatory Peptides 46 (3): 487-509. 23 July 1993

Circadian blood pressure variation in transgenic hypertensive rats.
Lemmer, B., Mattes, A., Boehm, M. and Ganten, D.
Hypertension 22 (1): 97-101. July 1993

Tissue renin-angiotensin systems. Their role in cardiovascular disease.
Lee, M.A., Boehm, M., Paul, M. and Ganten, D.
Circulation 87 (Suppl IV): 7-13. May 1993

Increased adrenal renin in transgenic hypertensive rats, TGR(mREN2)27, and its regulation by cAMP, angiotensin II and calcium.
Peters, J., Muenter, K., Bader, M., Hackenthal, E., Mullins, J.J. and Ganten, D.
Journal of Clinical Investigation 91 (3): 742-747. March 1993

Transgene Ratten, die in ihrem Genom mindestens ein menschliches Gen enthalten, das an der Blutdruckregulation beteiligt ist [Transgenic rats having at least one human gene in their genome, participating in the regulation of the blood-pressure].
Ganten, D., Mullins, J. and Murakami, K.
EP0528360A2 ; EP0528360A3 ; EP0528360B1. 24 February 1993

Selective activation of cardiac angiotensinogen gene expression in post-infarction ventricular remodeling in the rat.
Lindpaintner, K., Lu, W., Niedermaier, N., Schieffer, B., Just, H., Ganten, D. and Drexler, H.
Journal of Molecular and Cellular Cardiology 25 (2): 133-143. February 1993

Androgene regulieren die Transkriptionsrate der schweren alpha -Myosinkette im Herzen.
Kaling, M. and Morano, I.
In: Zellulaere Mechanismen der Herz-Kreislaufregulation. Pharmakologische und klinische Konsequenzen. Franz Gross Hypertonie Symposium, Schlosshotel Kronberg, 5.-7.Maerz 1992 . Schattauer, Stuttgart, 151-158. 1 January 1993

Angiotensinogen is cleaved to angiotensin in isolated rat blood vessels.
Hilgers, K.F., Hilgenfeldt, U., Veelken, R., Muley, T., Ganten, D., Luft, F.C. and Mann, J.F.
Hypertension 21 : 1030-1034. 1 January 1993

Angiotensinogen mRNA and pressor reactions to angiotensin in brain stem areas of spontaneously hypertensive rats.
Chai, C.Y., Hellmann, W., Tseng, C.J., Luft, F.C. and Ganten, D.
Clinical and Experimental Hypertension 15 : 709-725. 1 January 1993

Biesenthal consensus: Biesenthal vaccine initiative (Vaccines for peace).
Calderon, F., Drozdov, S.G., Fenner, F., Ganten, D., Geissler, E., Horoud, F., Kane, M., L'age-Stehr, J., Langen, P., Leitenberg, M., Melling, J., Morse, S.S., Netesov, S.V., Nixdorff, K., Pearson, G., Sandstroem, G., Subrahmanyam, D., Thraenert, O., Toth, T., Valette, M.L., Wheelis, M.L. and Woodall, J.P.
Politics and the Life Sciences 12 : 101-103. 1 January 1993

Cardiac angiotensin-II formation: the angiotensin-I converting- enzyme and human chymase.
Urata, H. and Ganten, D.
European Heart Journal 14 : 177-182. 1 January 1993

Cellular expression of angiotensin type-1 receptor mRNA in the kidney.
Meister, B., Lippoldt, A., Bunnemann, B., Inagami, T., Ganten, D. and Fuxe, K.
Kidney International 44 : 331-33. 1 January 1993

Cellular localization of angiotensin type 1 receptor and angiotensinogen mRNAs in the subfornical organ of the rat brain.
Lippoldt, A., Bunnemann, B., Metzger, R., Fuxe, K. and Ganten, D.
Neuroscience Letters 150 : 153-158. 1 January 1993

Dietary salt excess unmasks blunted aldosterone suppression and sodium retention in stroke-prone phenotype of the spontaneously hypertensive rat.
Volpe, M., Rubattu, S., Ganten, D., Enea, I., Russo, R., Lembo, G., Mirante, A., Condorelli, G. and Trimarco, B.
Journal of Hypertension 11 : 793-798. 1 January 1993

Expression of the mouse ren-2 gene in the small intestine is regulated by food intake.
Zhao, Y., Peters, J., Ganten, D. and Bader, M.
Pfluegers Archiv European Journal of Physiology 424 : 199-202. 1 January 1993

Extra-hepatic transcription of plasma prekallikrein gene in human and rat tissues.
Ciechanowicz, A., Bader, M., Wagner, J. and Ganten, D.
Biochemical and Biophysical Research Communications 197 : 1370-1376. 1 January 1993

Fast and widespread increase of basic fibroblast growth factor messenger RNA and protein in the forebrain after kainate-induced seizures.
Humpel, C., Lippoldt, A., Chadi, G., Ganten, D., Olson, L. and Fuxe, K.
Neuroscience 57 : 913-922. 1 January 1993

Festschrift anlaesslich der Gruendung des Max-Delbrueck-Centrum fuer Molekulare Medizin in Berlin-Buch. Symposium: "Wissenschaftsgeschichte und Molekulare Medizin in Berlin-Buch".
Bielka, H. and Ganten, D.
Max-Delbrueck-Centrum fuer Molekulare Medizin, Berlin-Buch. 1 January 1993

Gap junction protein connexin40 is preferentially expressed in vascular endothelium and conductive bundles of rat myocardium and is increased under hypertensive conditions.
Bastide, B., Neyses, L., Ganten, D., Paul, M., Willecke, K. and Traub, O.
Circulation Research 73 : 1138-1149. 1 January 1993

Gene regulation of beta-1-adrenergic receptor in genetically hypertensive rats.
Castellano, M., Paul, M., Beschi, M., Bachmann, J., Rizzoni, D., Porteri, E., Bettoni, G., Cinelli, A., Ganten, D. and Agabiti-Rosei, E.
Journal of Hypertension 11 (Suppl.) : S64-S65. 1 January 1993

High blood pressure maintenance in transgenic mRen-2 vs. Lyon genetically hypertensive rats.
Lo, M., Medeiros, I.A., Mullins, J.J., Ganten, D., Barres, C., Cerutti, C., Vincent, M. and Sassard, J.
American Journal of Physiology Renal Physiology 265 : R180-R186. 1 January 1993

Hormones, autacoids, neurotransmitters, and growth factors.
Ganten, D., Luft, F.C. and Kurokawa, K.
Current Opinion in Nephrology and Hypertension 2 : 1-4. 1 January 1993

Hypertension summer school 1992.
Ganten, D.
Clinical and Experimental Hypertension 15 : 617-618. 1 January 1993

Immobilization stress induces vasodepressor and altered neuroendocrine responses in the adult stroke-prone, spontaneously hypertensive male rat.
Narvaez, J.A., Aguirre, J.A., Haerfstrand, A., Eneroth, P., Ganten, D., Agnati, L.F. and Fuxe, K.
Acta Physiologica Scandinavica 149 : 491-501. 1 January 1993

Investigating the genetics of hypertension.
Bader, M., Paul, M. and Ganten, D.
ACE Report 99 : 6-10. 1 January 1993

Isolierte systolische Hypertonie im Alter.
Staessen, J., Ritz, E., Faulhaber, H.D., Gellert, J., Ganten, D. and Amery, A.
Deutsche Medizinische Wochenschrift 118 : 554-560. 1 January 1993

Membrane microviscosity does not correlate with blood pressure: a cosegregation study.
McLaren, Y., Kreutz, R., Lindpaintner, K., Bohr, D.F., Ganten, D., Reid, J.L. and Dominiczak, A.F.
Journal of Hypertension 11 : 25-30. 1 January 1993

Modulation of blood pressure and the renin-angiotensin system in transgenic and spontaneously hypertensive rats after ovariectomy.
Bachmann, J., Wagner, J., Haufe, C., Wystrychowski, A., Ciechanowicz, A. and Ganten, D.
Journal of Hypertension 11 (Suppl.5) : S226-S227. 1 January 1993

Modulation of tissue angiotensinogen gene expression by glycocorticoids, estrogens, and androgens in SHR and WKY rats.
Klett, C., Hellmann, W., Hackenthal, E. and Ganten, D.
Clinical and Experimental Hypertension 15 : 683-708. 1 January 1993

Molecular genetics of the SA-gene : cosegregation with hypertension and mapping to rat chromosome 1.
Lindpaintner, K., Hilbert, P., Ganten, D., Nadal-Ginard, B., Inagami, T. and Iwai, N.
Journal of Hypertension 11 (1): 19-23. 1 January 1993

Molekulare Medizin: Die Zukunft hat begonnen - ein Lichtblick fuer die Medizin von morgen.
Ganten, D.
Muenchener Medizinische Wochenschrift 135 : 12-13. 1 January 1993

Novel aspects on central 5 hydroxytryptamine neurotransmission focus on the cerebellum.
Fuxe, K., Agnati, L.F., Bjelke, B., Hedlund, P., Ueki, A., Tinner, B., Bunnemann, B., Steinbusch, H., Ganten, D. and Cintra, A.
In: Serotonin, the Cerebellum, and Ataxia : Meeting, Lyon, France, September 1991. Raven Press, New York, 1-36. 1 January 1993

Ontogenetic regulation of the mouse Ren-2d renin gene in transgenic hypertensive rats TGR(mREN2)27.
Zhao, Y., Bader, M., Kreutz, R., Fernandez-Alfonso, M.S., Zimmermann, F., Ganten, U., Metzger, R., Ganten, D., Mullins, J.J. and Peters, J.
American Journal of Physiology 265 : E699-E707. 1 January 1993

Photochemically induced focal cerebral ischemia in rat: time dependent and global increase in expression of basic fibroblast growth factor mRNA.
Lippoldt, A., Andbjer, B., Rosen, L., Richter, E., Ganten, D., Cao, Y., Pettersson, R.F. and Fuxe, K.
Brain Research 625 : 45-56. 1 January 1993

Polymorphism of the angiotensin-I converting enzyme gene Is apparently not related to high blood pressure - dutch hypertension and offspring study.
Schmidt, S., Vanhooft, I.M.S., Grobbee, D.E., Ganten, D. and Ritz, E.
Journal of Hypertension 11 : 345-348. 1 January 1993

Primaerer Hyperrenismus. Eine seltene Ursache der sekundaeren arteriellen Hypertonie.
Kreutz, R., Zhou, H., Pfeifer, U., Gasc, J.M., Ganten, D. and Kessler, F.J.
Deutsche Medizinische Wochenschrift 118 : 1110-1114. 1 January 1993

Progress in molecular medicine. From experimental genetics to the treatment of hypertensive patients.
Ganten, D., Kreutz, R., Bader, M. and Wagner, J.
Chinese Medical Journal 106 : 375-384. 1 January 1993

Progress in molecular medicine: methods and their application in hypertension research.
Ganten, D.
In: Herkunft, Krise und Wandlung der modernen Medizin. Kulturgeschichtliche, wissenschaftsphilosophische und anthropologische Aspekte. Kleine, Bielefeld, 394-415. 1 January 1993

Regional expression of angiotensinogen messenger RNA in the brain of one-week-old, adult and old male rats.
Bunnemann, B., Metzger, R., Fuxe, K. and Ganten, D.
Developmental Brain Research 73 : 41-45. 1 January 1993

Regulation adrenaler Aldosteronsekretion und adrenalen Renins in TGR(mREN2)27.
Peters, J., Djavidani, B., Sander, M., Bader, M. and Ganten, D.
Nieren- und Hochdruckkrankheiten 22 : 364-368. 1 January 1993

Regulation der Herzfunktion: Bedeutung der intrazellulaeren Proteinphosphorylierung.
Krause, E.G., Bartel, S., Karczewski, P. and Lindeke, A.
In: Zellulaere Mechanismen der Herz-Keislaufregulation. Pharmakologische und klinische Konsequenzen. Schattauer, Stuttgart [u.a.], 69-80. 1 January 1993

Renin gene expression and hypertension in transgenic animals.
Bader, M., Lee, M.A., Zhao, Y., Boehm, M., Bachmann, J., Sander, M., Djavidani, B., Bachmann, S., Zimmermann, F., Wilbertz, J., Zeh, K., Wagner, J., Peters, J. and Ganten, D.
In: Cellular and Molecular Biology of the Renin-Angiotensin System. CRC Press, Boca Raton, 60-93. 1 January 1993

Round table 1. Do transgenic techniques help us to understand hypertension?
Unger, T., Ganten, D., Johnston, C.I., Lever, A.F., Mullins, J.J., Sassard, J. and van Zwieten, P.A.
Journal of Hypertension 11 (Suppl.5) : S374-S379. 1 January 1993

Sexual dimorphism of cardiovascular function: the role of androgens.
Bachmann, J., Ganten, U., Stock, G. and Ganten, D.
In: Sex Steroids and the Cardiovascular System (Schering Foundation Workshop ; 5). Springer, Berlin [u.a.], 9-30. 1 January 1993

The human renin-angiotensin system in transgenic rats - new tools for antihypertensive therapy.
Wagner, J., Paul, M. and Ganten, D.
In: Transgenic Animals as Model Systems for Human Diseases (Schering Foundation Workshop ; 6). Springer, Berlin [u.a.], 1-23. 1 January 1993

The renin-angiotensin paradigm. practical therapeutical consequences of basic research.
Ganten, D.
Arzneimittelforschung 43 : 191-197. 1 January 1993

The renin-angiotensin system in the brain. Localization and functional significance.
Paul, M., Bader, M., Steckelings, U.M., Voigtlaender, T. and Ganten, D.
Arzneimittelforschung 43 : 207-213. 1 January 1993

The renin-angiotensin system in transgenic rats : characteristics and functional studies.
Wagner, J. and Ganten, D.
Seminars in Nephrology 13 : 586-592. 1 January 1993

The transition from experimental to clinical pharmacology: the renin-angiotensin paradigm.
Ganten, D.
Journal of Cardiovascular Pharmacology 22 (Suppl.1) : S14-S29. 1 January 1993

Tissue distribution of angiotensinogen mRNA during experimental inflammation.
Klett, C., Hellmann, W., Ganten, D. and Hackenthal, E.
Inflammation 17 : 183-197. 1 January 1993

Transgenic rats as models to study candidate genes for hypertension.
Paul, M. and Ganten, D.
In: Progress in Endocrinology, Ninth International Congress of Endocrinology, Nice, France, September 1992. International Congress Symposium and Seminars Series ; 3 . Parthenon, London, 71-73. 1 January 1993

Update on the renin-angiotensin system. Recent advances in molecular biology.
Wagner, J., Fernandez-Alfonso, M.S., Bachmann, J., Bader, M., Paul, M. and Ganten, D.
Nutrition, Metabolism, and Cardiovascular Diseases 3 : 197-203. 1 January 1993

Vascular conversion of angiotensin I in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats.
Hilgers, K.F., Veelken, R., Mai, M., Ganten, U., Ganten, D., Luft, F.C. and Mann, J.F.
Journal of Hypertension 11 : 1053-1059. 1 January 1993

WHL Hypertension League-Yearbook 1993.
Ganten, D., Strasser, T. and Poetzsch, J.
WHO, Geneva. 1 January 1993

Zellulaere Mechanismen der Herz-Kreislaufregulation: Pharmakologische und klinische Konsequenzen. Franz Gross Hypertonie Symposium, Schlosshotel Kronberg, 5.-7. Maerz 1992.
Ganten, D.
Schattauer, Stuttgart. 1 January 1993

1992

The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27.
Sander, M., Bader, M., Djavidani, B., Masergluth, C., Vecsei, P., Mullins, J.J., Ganten, D. and Peters, J.
Endocrinology 131 (2): 807-814. 1 August 1992

Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes.
Ganten, D., Wagner, J., Zeh, K., Bader, M., Michel, J.B., Paul, M., Zimmermann, F., Ruf, P., Hilgenfeldt, U., Ganten, U., Kaling, M., Bachmann, S., Fukamizu, A., Mullins, J.J. and Murakami, K.
Proceedings of the National Academy of Sciences of the United States of America 89 : 7806-7810. August 1992

Rat gene mapping using PCR-analyzed microsatellites.
Serikawa, T., Kuramoto, T., Hilbert, P., Mori, M., Yamada, J., Dubay, C.J., Lindpaintner, K., Ganten, D., Guenet, J.L., Lathrop, G.M. and Beckmann, J.S.
Genetics 131 (3): 701-721. 1 July 1992

Increased vascular angiotensin formation in female rats harboring the mouse ren-2 gene.
Hilgers, K.F., Peters, J., Veelken, R., Sommer, M., Rupprecht, G., Ganten, D., Luft, F.C. and Mann, J.F.
Hypertension 19 (6 Pt 2): 687-691. 1 June 1992

Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats.
Bader, M., Zhao, Y., Sander, M., Lee, M.A., Bachmann, J., Boehm, M., Djavidani, B., Peters, J., Mullins, J.J. and Ganten, D.
Hypertension 19 (6 Pt 2): 681-686. 1 June 1992

Adrenal renin is released into the circulation of the hypertensive transgenic rat TGR(mRen-2)27.
Tokita, Y., Yamaguchi, T., Franco-Saenz, R., Mulrow, P.J. and Ganten, D.
Transactions of the Association of American Physicians CV : 123-132. 1 January 1992

Basic methodology in the molecular characterization of genes.
Bader, M., Kaling, M., Metzger, R., Peters, J., Wagner, J. and Ganten, D.
Journal of Hypertension 10 : 9-16. 1 January 1992

Chromosomal mapping of genetic loci associated with hereditary hypertension in the rat.
Lindpaintner, K., Hilbert, P., Ganten, D., Georges, M. and Lathrop, G.M.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats and Related Studies. Colloque Inserm ; 218 . John Libbey Eurotext, Paris, 313-315. 1 January 1992

Contributions of animal models for understanding hypertension.
Linz, W. and Ganten, D.
Progress in Cardiology 5 : 25-36. 1 January 1992

Correct expression of the transgene in the brain of hypertensive transgenic mice carrying the rat angiotensinogen gene.
Bunnemann, B., Kimura, S., Mullins, J.J., Zimmermann, F., Ganten, D. and Kaling, M.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertension Rats and Related Studies. Colloque Inserm ; 218 . John Libbey Eurotext, Paris, 309-311. 1 January 1992

Effects of angiotensin-converting enzyme inhibitors on tissue renin angiotensin systems.
Lee, M.A., Paul, M., Boehm, M. and Ganten, D.
American Journal of Cardiology 70 : C12-C19. 1 January 1992

Expression des Ren-2-Gens der Maus im Duenndarm von DBA/2-Maeusen und transgenen Ratten.
Zhao, Y., Peters, J., Matsuda, T., Mullins, J.J., Bader, M. and Ganten, D.
Nieren- und Hochdruckkrankheiten 21 : 642-643. 1 January 1992

Gefaess- und Herzhypertrophie : von der Molekularbiologie zur Therapie : Franz-Gross-Hypertonie-Symposium, Schlosshotel Kronberg, 7. - 9. Maerz 1991.
Ganten, D.
Schattauer, Stuttgart [u.a.]. 1 January 1992

Genetic mapping in hypertension.
Dzau, V.J., Jacob, H.J., Lindpaintner, K., Ganten, D. and Lander, E.S.
Journal of Vascular Surgery 15 : 930-930. 1 January 1992

Genetic variation in hypertensive and control strains - what are we controlling for anyway (editorial).
Lindpaintner, K., Kreutz, R. and Ganten, D.
Hypertension 19 : 428-430. 1 January 1992

Gesteigerte Aldosteronbiosynthese in TGR(mREN2)27: Funktionelle Bedeutung eines lokalen intraadrenalen Renin-Angiotensin-Systems.
Peters, J., Djavidani, B., Muenter, K., Bader, M., Sander, M., Mullins, J.J. and Ganten, D.
Nieren- und Hochdruckkrankheiten 21 : 545-546. 1 January 1992

High blood pressure in transgenic mice carrying the rat angiotensinogen gene.
Kimura, S., Mullins, J.J., Jacob, H.J., Fuxe, K., Ganten, D. and Kaling, M.
EMBO Journal 11 : 821-827. 1 January 1992

Identification of chromosomal loci associated with genetic hypertension in the rat.
Lindpaintner, K., Hilbert, P., Ganten, D., Georges, M. and Lathrop, M.
Nieren- und Hochdruckkrankheiten 21 : 549-551. 1 January 1992

Left ventricular remodeling after myocardial infarction - does the cardiac renin angiotensin system play a role?
Lindpaintner, K., Niedermaier, N., Drexler, H. and Ganten, D.
Journal of Cardiovascular Pharmacology 20 : S41-S47. 1 January 1992

Maligne Hypertonie: Pathophysiologie - Klinik - Therapie.
Wagner, J., Ritz, E. and Ganten, D.
Deutsches Aerzteblatt 89 : 2624-2629. 1 January 1992

Mechanisms of cardiac growth. The role of the renin-angiotensin system.
Fernandez-Alfonso, M.S., Ganten, D. and Paul, M.
Basic Research in Cardiology 87 : 173-181. 1 January 1992

Molecular genetics of hypertension.
Kreutz, R., Higuchi, M. and Ganten, D.
Clinical and Experimental Hypertension : 15-34. 1 January 1992

Molekulare Genetik der Hypertonie.
Ganten, D., Pfaff, G.M. and Kreutz, R.
Nieren- und Hochdruckkrankheiten 21 : 540-544. 1 January 1992

Molekulargenetik bei arterieller Hypertonie.
Kreutz, R., Peters, J. and Ganten, D.
Deutsche Medizinische Wochenschrift 117 : 1461-1461. 1 January 1992

Molekulargenetische Marker sollen Hochdruck-Forschung vorantreiben. Das Renin-Gen hat eine pathophysiologische Relevanz fuer die Hypertonie.
Ganten, D., Kreutz, R. and Lindpaintner, K.
Aerzte Zeitung 135 : 11-13. 1 January 1992

Pharmacology of Antihypertensive Therapeutics.
Ganten, D. and Bartsch, W.
Handbook of Experimental Pharmacology ; 93 . Springer, Berlin [u.a.]. 1 January 1992

Primary hypertension and the renin angiotensin system - from the laboratory experiment to clinical relevance.
Bader, M., Kreutz, R., Wagner, J., Zeh, K., Boehm, M., Paul, M. and Ganten, D.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats, (Colloque Inserm ; 218). John Libbey Eurotext, Paris, 359-371. 1 January 1992

Primary hypertension in Germany: Epidemiology and treatment.
Wagner, J., Haufe, C.C. and Ganten, D.
Curr Circ 3 : 21-24. 1 January 1992

Regulation der Herzmuskelzelle auf molekularer Ebene : Pharmakologische und klinische Bedeutung. Franz-Gross-Hypertonie-Symposium Kronberg, 5. - 7. Maerz 1992.
Ganten, D., Mall, G. and Hofmann, F.
Fortschritte der Medizin 110 (Suppl 126): 2-19. 1 January 1992

Regulation of hepatic angiotensinogen synthesis and secretion by steroid hormones.
Klett, C., Ganten, D., Hellmann, W., Kaling, M., Ryffel, G.U., Weimarehl, T. and Hackenthal, E.
Endocrinology 130 : 3660-3668. 1 January 1992

Renale Renin-mRNA-Expression bei Patienten mit Glomerulonephritis und Hypertonie.
Wagner, J., Paul, M., Haufe, C.C., Volk, S., Ganten, D. and Ritz, E.
Nieren- und Hochdruckkrankheiten 21 : 547-548. 1 January 1992

Report on the Hypertension Summer School (HTSS) Sept. 15-20, 1991.
Ganten, D.
Journal of Human Hypertension 6 : 247-247. 1 January 1992

Role of endocrine brain in the control of hypertension angiotensin II and atrial natriuretic peptide in the brain.
Badoer, E., Unger, T. and Ganten, D.
In: Comprehensive Endocrinology : Brain Endocrinology. Raven Press, New York, 403-430. 1 January 1992

Search for genetic determinants of environmental susceptibility in hypertension: effect of heat, immobilization stress and endotoxin.
Kunes, J., Pravenec, M., Kren, V., Klir, P., Ganten, D., Mullins, J.J., Tremblay, J. and Hamet, P.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats. Colloque Inserm ; 218 . John Libbey Eurotext, Paris, 333-335. 1 January 1992

Sexual dimorphism of blood pressure in transgenic rats TGR(m REN2)27 harboring the murine Ren-2 gene.
Bachmann, J., Ganten, U., Zimmermann, F., Mullins, J.J., Stock, G. and Ganten, D.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats and Related Studies. Colloque Inserm ; 218 . John Libbey Eurotext, Paris, 353-355. 1 January 1992

Sexueller Dimorphismus des Blutdrucks bei TGR(mREN2)27: Einfluss von Androgenen.
Bachmann, J., Ganten, U., Stock, G. and Ganten, D.
Nieren- und Hochdruckkrankheiten 21 : 599-601. 1 January 1992

The Gross, Franz Hypertension Symposium Series - Introduction.
Ganten, D.
Journal of Cardiovascular Pharmacology 20 : 5-6. 1 January 1992

The brain renin-angiotensin system - localization and general significance.
Bunnemann, B., Fuxe, K. and Ganten, D.
Journal of Cardiovascular Pharmacology 19 (Suppl 6): S51-S62. 1 January 1992

The brain renin-angiotensin system: a model for the synthesis of peptides in the brain (Commentary).
Ganten, D. and Speck, G.
Biochemical Pharmacology 27 : 2379-2389. 1 January 1992

The distribution of angiotensin II AT1 receptor subtype messenger RNA in the rat brain.
Bunnemann, B., Iwai, N., Metzger, R., Fuxe, K., Inagami, T. and Ganten, D.
Neuroscience Letters 142 : 155-158. 1 January 1992

The molecular basis of cardiovascular hypertrophy: the role of the renin angiotensin system.
Paul, M. and Ganten, D.
Journal of Cardiovascular Pharmacology 19 (Suppl 5): S51-S58. 1 January 1992

The role of adrenal renin in steroid metabolism and development of hypertension in transgenic rats TGR(Messenger REN2).
Peters, J., Sander, M., Munter, K., Lee, M.A., Djavidani, B., Bader, M., Maser-Gluth, C., Vecsei, P., Ganten, D. and Mullins, J.J.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats (Colloque Inserm ; 218). John Libbey Eurotext, Paris, 345-347. 1 January 1992

The semi-quantitative distribution and cellular localization of angiotensinogen messenger RNA in the rat brain.
Bunnemann, B., Fuxe, K., Metzger, R., Bjelke, B. and Ganten, D.
Journal of Chemical Neuroanatomy 5 : 245-262. 1 January 1992

The tissue renin-angiotensin systems in cardiovascular disease.
Paul, M., Bachmann, J. and Ganten, D.
Trends in Cardiovascular Medicine 2 : 94-99. 1 January 1992

Transgenic rats carrying the mouse renin gene - morphological characterization of a low-renin hypertension model.
Bachmann, S., Peters, J., Engler, E., Ganten, D. and Mullins, J.J.
Kidney International 41 : 24-36. 1 January 1992

Wissenschaft - Wirtschaft - Oeffentlichkeit : Gemeinsames und Trennendes, Bruecken und Huerden in der Forschung. Konferenz der Akademien der Wissenschaften der Bundesrepublik Deutschland.
Schettler, G., Ganten, D. and Baildon, R.
Springer, Berlin [u.a.]. 1 January 1992

Zonal distribution and regulation of adrenal renin in a transgenic model of hypertension in the rat.
Yamaguchi, T., Tokita, Y., Franco-Saenz, R., Mulrow, P.J., Peters, J. and Ganten, D.
Endocrinology 131 : 1955-1962. 1 January 1992

Cardiovascular hypertrophy: from molecular biology to clinics, therapy, and prevention. Franz Gross Hypertension Symposium. Kronberg, March 7-9, 1991.
Ganten, Detlev, ed.
Journal of Cardiovascular Pharmacology, 20 (Suppl 1). Raven Press, New York, S1-64. 1992

1991

The influence of cold stress on the myosin heavy chain expression of cardiac and smooth muscle in normotensive and spontaneously hypertensive female rats.
Adler, K., Boels, P., Ganten, U., Ganten, D. and Morano, I.
Circulation Research 69 (6): 1640-1644. December 1991

Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats.
Hilbert, P., Lindpaintner, K., Beckmann, J.S., Serikawa, T., Soubrier, F., Dubay, C.J., Cartwright, P., De Gouyon, B., Julier, C., Takahashi, S., Vincent, M., Ganten, D., Georges, M. and Lathrop, G.M.
Nature 353 (6344): 521-529. 10 October 1991

Genetic mapping of a gene causing hypertension in the stroke- prone spontaneously hypertensive rat.
Jacob, H.J., Lindpaintner, K., Lincoln, S.E., Kusumi, K., Bunker, R.K., Mao, Y.P., Ganten, D., Dzau, V.J. and Lander, E.S.
Cell 67 (1): 213-224. 4 October 1991

Angiotensin II immunoreactivity in the human striatum and hippocampus of elderly controls and patients with senile dementia of the Alzheimer type and multi-infarct dementia.
Savaskan, E., Hoechli, M., Ganten, D. and Chan-Palay, V.
Dementia 2 : 314-323. 1 January 1991

Angiotensin and cell growth: a link to cardiovascular hypertrophy? [editorial].
Schelling, P., Fischer, H. and Ganten, D.
Journal of Hypertension 9 : 3-15. 1 January 1991

Angiotensin in hypertension: new aspects.
Ganten, D., Paul, M., Bader, M. and Mullins, J.J.
In: Peptide Regulation of Cardiovascular Function. Academic Press, Tokyo, 167-190. 1 January 1991

Blutdruckselbstmessung.
Baildon, R. and Ganten, D.
Allgemeinarzt 8 : 616-619. 1 January 1991

Cell biology in hypertension.
Kreutz, R. and Ganten, D.
Current Opinion in Cardiology 6 : 680-685. 1 January 1991

Changes in the central ANF-system of renovascular hypertensive rats.
Bahner, U., Geiger, H., Palkovits, M., Ganten, D., Klotz, B. and Heidland, A.
Kidney International 39 : 33-38. 1 January 1991

Characterization of rat intestinal angiotensin II receptors.
Schinke, M., Doods, H.N., Ganten, D., Wienen, W. and Entzeroth, M.
European Journal of Pharmacology 204 : 165-170. 1 January 1991

Das Renin-Angiotensin-System im Gehirn.
Ganten, D., Bunnemann, B. and Fuxe, K.
In: Herz-Kreislauf-Regulation, Organprotektion und Organschaeden. Schattauer, Stuttgart, 177-183. 1 January 1991

Die Bedeutung extrarenaler Reninsysteme in der Pathogenese der arteriellen Hypertonie.
Paul, M. and Ganten, D.
Verhandlungen der Deutschen Gesellschaft fuer Innere Medizin 97 : 539-544. 1 January 1991

Differences in rat kidney morphology between males, females and testosterone-treated females.
Oudar, O., Elger, M., Bankir, L., Ganten, D., Ganten, U. and Kriz, W.
Renal Physiology and Biochemistry 14 : 92-102. 1 January 1991

Enhanced cardiac angiotensinogen gene expression and angiotensin converting enzyme activity in tachypacing-induced heart failure in rats.
Finckh, M., Hellmann, W., Ganten, D., Furtwangler, A., Allgeier, J., Boltz, M. and Holtz, J.
Basic Research in Cardiology 86 : 303-316. 1 January 1991

Extrarenal Systems: the Brain.
Bunnemann, B., Fuxe, K. and Ganten, D.
In: The Renin-Angiotensin System, Volume 1: Biochemistry Physiology. Gower Medical Publishing, London [u.a.], 41.1-41.17. 1 January 1991

Funktionelle Bedeutung des kardialen Renin-Angiotensin-Sytems.
Dietz, R., Waas, W., Haberbosch, W., Suesselbeck, T., Hauck, S. and Osterziel, K.J.
In: Herz-Kreislauf-Regulation, Organprotektion und Organschaeden. Schattauer, Stuttgart [u.a.], 193-202. 1 January 1991

Genetic basis of hypertension.
Ganten, D., Takahashi, S., Lindpaintner, K. and Mullins, J.J.
Hypertension 18 : III109-III114. 1 January 1991

Glucocorticoid- and estrogen-responsive elements in the 5'- flanking region of the rat angiotensinogen gene.
Feldmer, M., Kaling, M., Takahashi, S., Mullins, J.J. and Ganten, D.
Journal of Hypertension 9 : 1005-1012. 1 January 1991

Herz-Kreislauf-Regulation, Organprotektion und Organschaeden : Franz Gross Hypertonie Symposium, Schlosshotel Kronberg, 1. - 3. Maerz 1990.
Ganten, D. and Mall, G.
Schattauer, Stuttgart [u.a.]. 1 January 1991

Kardiovaskulaere Hypertrophie: Bedeutung des Renin-Angiotensin Systems.
Paul, M., Wagner, J. and Ganten, D.
In: Herz-Kreislauf-Regulation, Organprotektion und Organschaeden. Schattauer, Stuttgart, 99-108. 1 January 1991

Local angiotensin formation in hindlimbs of uremic hypertensive and renovascular hypertensive rats.
Kuczera, M., Hilgers, K.F., Lisson, C., Ganten, D., Hilgenfeldt, U., Ritz, E. and Mann, J.F.
Journal of Hypertension 9 : 41-48. 1 January 1991

Molekulare Genetik des Bluthochdrucks.
Kreutz, R., Lindpaintner, K. and Ganten, D.
Muenchener Medizinische Wochenschrift 133 : 724-728. 1 January 1991

Preparation and analysis of transgenic rats expressing the mouse Ren-2 gene.
Lee, M.A., Zhao, Y., Peters, J., Ganten, D., Zimmermann, F., Ganten, U., Bachmann, S., Bader, M. and Mullins, J.J.
Journal of Vascular Medicine and Biology 3 : 50-54. 1 January 1991

Sexual dimorphism of blood pressure: possible role of the renin- angiotensin system.
Bachmann, J., Feldmer, M., Ganten, U., Stock, G. and Ganten, D.
Journal of Steroid Biochemistry and Molecular Biology 40 : 511-515. 1 January 1991

The brain renin angiotensin system and its possible involvement in volume transmission.
Bunnemann, B., Fuxe, K., Bjelke, B. and Ganten, D.
In: Volume Transmission in the Brain : Novel Mechanisms for Neural Transmission , Conference, Stockholm, Sweden, September 28-30, 1989 (Advances in Neuroscience ; 1). Raven Press, New York, 131-158. 1 January 1991

The cardiac renin-angiotensin system. An appraisal of present experimental and clinical evidence.
Lindpaintner, K. and Ganten, D.
Circulation Research 68 : 905-921. 1 January 1991

The cardiac renin-angiotensin system: a synopsis of current experimental and clinical data.
Lindpaintner, K. and Ganten, D.
News in Physiological Sciences 6 : 227-232. 1 January 1991

The cardiac renin-angiotensin system: a synopsis of current experimental and clinical data.
Lindpaintner, K. and Ganten, D.
Acta Cardiologica 46 : 385-397. 1 January 1991

The role of neuropeptides in cardiovascular regulation.
Ganten, D., Paul, M. and Lang, R.E.
Cardiovascular Drugs and Therapy 5 : 119-130. 1 January 1991

Tissue distribution of ren-2 expression in transgenic rats.
Peters, J., Bader, M., Ganten, D. and Mullins, J.J.
In: Genetic Approaches to Coronary Heart Disease and Hypertension. Springer, Berlin [u.a.], 74-80. 1 January 1991

Tissue renin-angiotensin systems and their modulation: the heart as a paradigm for new aspects of converting enzyme inhibition.
Lindpaintner, K. and Ganten, D.
Cardiology 79 (Suppl 1): 32-44. 1 January 1991

Transgenic rats: new animal models in hypertension research. Invited lecture.
Ganten, D., Lindpaintner, K., Ganten, U., Peters, J., Zimmermann, F., Bader, M. and Mullins, J.J.
Hypertension 17 : 843-855. 1 January 1991

Vascular production and regulation of angiotensin.
Hilgers, K.F., Mann, J.F., Hilgenfeldt, U. and Ganten, D.
Blood Vessels 28 : 201-209. 1 January 1991