2026

Spreading α-synuclein rewires organelle communication and impairs neuron–astrocyte mitochondrial quality control.
Fritsch, Elisabeth ORCID: https://orcid.org/0000-0002-4207-0395, Horvatovic, Kamelija ORCID: https://orcid.org/0000-0002-3424-1326, Santos Otte, Paula ORCID: https://orcid.org/0009-0009-4556-0574, Koudelka, Tomas ORCID: https://orcid.org/0009-0008-2895-6051, Rossius, Jana ORCID: https://orcid.org/0009-0000-6011-9714, Braeuning, Caroline ORCID: https://orcid.org/0009-0007-1439-9920, Breimann, Laura ORCID: https://orcid.org/0000-0001-7702-5749, Piazza, Ilaria ORCID: https://orcid.org/0000-0001-5895-6134 and Birol, Melissa ORCID: https://orcid.org/0000-0003-3397-8446
bioRxiv : 2026.06.19.733342. 23 June 2026

circVDJ-seq for T cell clonotype detection in single-cell and spatial multi-omics.
Plumbom, Izabela ORCID: https://orcid.org/0009-0006-3720-3700, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Raspe, Raphael, Pascual-Reguant, Anna, Theurillat, Ilan ORCID: https://orcid.org/0000-0002-1125-1951, Pentimalli, Tancredi Massimo ORCID: https://orcid.org/0000-0002-8461-7918, Hsieh, Yu-Hsin ORCID: https://orcid.org/0000-0003-3037-8728, Gil, Marine ORCID: https://orcid.org/0000-0002-3885-7806, Dietrich, Carola, Seeger-Zografakis, Michaela, Quedenau, Claudia ORCID: https://orcid.org/0000-0002-6846-4915, Wilde, Jeannine, Braeuning, Caroline ORCID: https://orcid.org/0009-0007-1439-9920, Fischer, Cornelius ORCID: https://orcid.org/0000-0003-0329-2435, Schuelke, Markus ORCID: https://orcid.org/0000-0003-2824-3891, Seitz, Volkhard, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Eggert, Angelika, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Borodina, Tatiana ORCID: https://orcid.org/0000-0002-6978-016X, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Altmueller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Hauser, Anja Erika and Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295
Genome Medicine 18 (1): 84. 11 June 2026

Unraveling the single-cell spatial landscapes of melanoma brain metastases.
Manukyan, Artür ORCID: https://orcid.org/0000-0002-0441-9517, Peters, Kristin, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Fusco, Federico, Geserick, Felicitas, Rossner, Florian, Lehmann, Annika, Kleo, Karsten ORCID: https://orcid.org/0000-0001-9136-6902, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Altmüller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Plumbom, Izabela ORCID: https://orcid.org/0009-0006-3720-3700, Akalin, Altuna ORCID: https://orcid.org/0000-0002-0468-0117, Jürchott, Karsten, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Delbridge, Claire, Sendler, Matthias, Radke, Josefine ORCID: https://orcid.org/0000-0001-9860-2007 and Redmer, Torben ORCID: https://orcid.org/0000-0002-0050-9478
medRxiv : 2025.08.29.25334740v3. 3 June 2026

Spermidine mitigates immune cell senescence and boosts vaccine responses in healthy older adults -- a pilot study.
Alsaleh, Ghada, Ali, Mohammad ORCID: https://orcid.org/0000-0003-0170-7182, Kayvanjoo, Amir Hossein ORCID: https://orcid.org/0000-0003-1315-8336, Liu, Feng, Moreau, Tanaïs, Bibi, Sagida, Luo, Lin, Govender, Melissa, Carroll, Miles, Hofer, Sebastian J., Tobias, Eisenberg, Magnes, Christoph, Kell, Loren ORCID: https://orcid.org/0000-0003-1322-2027, Chung, Christopher, Deng, Yu, Bhandari, Aneesha, Garner, Lucy ORCID: https://orcid.org/0000-0002-6461-252X, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Chen, Liye, Kronsteiner-Dobramysl, Barbara, Dunachie, Susie, Spiller, Owen B. ORCID: https://orcid.org/0000-0002-9117-6911, Lambe, Teresa, Klenerman, Paul, Jones, Lucy C. and Simon, A. Katharina ORCID: https://orcid.org/0000-0002-4077-7995
Aging Cell 25 (6): e70545. June 2026

Endothelial YAP/TAZ rewiring under cardiometabolic stress drives sex-divergent vascular remodeling in heart failure with preserved ejection fraction.
Klaus-Bergmann, Alexandra ORCID: https://orcid.org/0000-0002-1164-3322, Sievers, Laura Katharina ORCID: https://orcid.org/0000-0002-4677-5181, Versnjak, Jakob, Koch, Katharina, Nawara, Tomasz ORCID: https://orcid.org/0000-0002-4801-4095, Bartels-Klein, Eireen, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Weiner 3rd, January ORCID: https://orcid.org/0000-0003-1438-7819, Meier, Katja, Hollfinger, Irene ORCID: https://orcid.org/0000-0002-6233-8395, Kamer, Ilona, Taube, Martin, Heuser, Arnd ORCID: https://orcid.org/0000-0002-3334-960X, Borodina, Tatiana ORCID: https://orcid.org/0000-0002-6978-016X, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Potente, Michael ORCID: https://orcid.org/0000-0002-5689-0036, Landmesser, Ulf ORCID: https://orcid.org/0000-0002-0214-3203, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Kelm, Marcus, Muller, Dominik N. ORCID: https://orcid.org/0000-0003-3650-5644 and Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384
bioRxiv : 2026.05.07.723127. 13 May 2026

Epithelial mesenchymal transition initiates precancer states in BRCA1 mutation carriers.
Bar-Hai, Neta, Ben-Yishay, Rakefet, Arbili-Yarhi, Sheli, Bernstein-Molho, Rinat, Goldinger, Gil, Balint-Lahat, Nora, Menes, Tehillah, Herman, Naama, Noy, Vered, Mansour, Aiham, Globus, Opher, Hilman, Pnina, Zehavi, Yonathan, Eizenberg-Magar, Inbal, Mahammadov, Elmir ORCID: https://orcid.org/0000-0003-0008-1413, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Antebi, Yaron E., Berger, Raanan and Ishay-Ronen, Dana ORCID: https://orcid.org/0000-0003-0425-1408
bioRxiv : 2026.05.06.723061. 11 May 2026

CACNB3 defects are associated with infantile idiopathic nystagmus.
Jüschke, Christoph ORCID: https://orcid.org/0000-0001-5842-4824, Linsel, Kira, Owczarek-Lipska, Marta, Brandt, Nicola ORCID: https://orcid.org/0000-0003-2483-9292, Zunken, Sarah, Altmüller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Preising, Markus N. ORCID: https://orcid.org/0000-0002-1596-5978, Kastrati, Dennis, Thiele, Holger, Thomas, Mervyn G., Nürnberg, Peter ORCID: https://orcid.org/0000-0002-7228-428X, Lorenz, Birgit, Kellner, Ulrich ORCID: https://orcid.org/0000-0001-5221-4631, Bräuer, Anja U. ORCID: https://orcid.org/0000-0003-3651-1470, Korenke, G. Christoph, Gottlob, Irene and Neidhardt, John ORCID: https://orcid.org/0000-0002-9205-8394
Brain Communications 8 (2): fcag034. 7 February 2026

Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection.
Pfefferkorn, Anna Maria ORCID: https://orcid.org/0000-0002-7126-9838, Jahn, Lorenz ORCID: https://orcid.org/0009-0003-4229-3059, Gauthier, Patrick T. ORCID: https://orcid.org/0000-0002-6103-8307, Kulow, Vera Anna ORCID: https://orcid.org/0000-0002-4226-6697, Roeles, Johannes, Müller-Bötticher, Niklas, Gerhardt, Louisa M.S., Leiz, Janna ORCID: https://orcid.org/0000-0002-6531-7047, Sarfraz, Sadia, Plumbom, Izabela ORCID: https://orcid.org/0009-0006-3720-3700, Greite, Robert, Lovric, Svjetlana ORCID: https://orcid.org/0000-0003-3953-9794, Gamrekelashvili, Jaba ORCID: https://orcid.org/0000-0001-7533-6906, Limbourg, Florian, Schmitz, Jessica ORCID: https://orcid.org/0000-0001-9843-7339, Bräsen, Jan Hinrich ORCID: https://orcid.org/0000-0002-2863-3067, Scheffner, Irina ORCID: https://orcid.org/0000-0002-5930-1866, Sauer, Igor M. ORCID: https://orcid.org/0000-0001-9355-937X, Aigner, Felix, Altmüller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Gwinner, Wilfried ORCID: https://orcid.org/0000-0003-1703-893X, Ishaque, Naveed ORCID: https://orcid.org/0000-0002-8426-901X, Fähling, Michael ORCID: https://orcid.org/0000-0003-1079-5049, Schmidt-Ott, Kai M. ORCID: https://orcid.org/0000-0002-7700-7142, Halloran, Philip F., Ashraf, Muhammad Imtiaz ORCID: https://orcid.org/0000-0002-6789-5393 and Hinze, Christian ORCID: https://orcid.org/0000-0003-2526-1621
Nature Communications 17 (1): 1060. 28 January 2026

Complex human hear bearing skin organoids reveal cell type specific susceptibility and innate immune responses to Herpes Simplex Virus 1.
Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Albertini, Silvia ORCID: https://orcid.org/0000-0002-8540-5378, Friedel, Caroline C. ORCID: https://orcid.org/0000-0003-3569-4877, Manukyan, Artür ORCID: https://orcid.org/0000-0002-0441-9517, Winterfeldt, Annalena, Bracker, Nina, Huang, Jiabin ORCID: https://orcid.org/0000-0002-3480-7115, Krasemann, Susanne ORCID: https://orcid.org/0000-0001-8795-818X, Plumbon, Izabela ORCID: https://orcid.org/0009-0006-3720-3700, Altmüller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Reimer, Rudolph, Schneider, Carola, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Hafezi, Wali, Hansen, Arne, Grundhoff, Adam ORCID: https://orcid.org/0000-0003-0940-7045, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Fischer, Nicole ORCID: https://orcid.org/0000-0002-5092-8179 and Czech-Sioli, Manja ORCID: https://orcid.org/0000-0002-7720-3282
bioRxiv : 2025.02.10.637415v2. 12 January 2026

The dorsal aortic compartment is a developmental source of brown adipose tissue in mice.
Heider, Sophie ORCID: https://orcid.org/0000-0003-4874-6971, Fischer, Cornelius ORCID: https://orcid.org/0000-0003-0329-2435, Secener, Ali Kerim ORCID: https://orcid.org/0000-0003-4806-2852, Vallecillo-Garcı́a, Pedro, Kotsaris, Georgios, Meisen, Zarah G., Pawolski, Verena, Giesecke-Thiel, Claudia ORCID: https://orcid.org/0000-0002-5927-7018, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Schulz, Tim J. ORCID: https://orcid.org/0000-0002-8413-3972, Sauer, Sascha ORCID: https://orcid.org/0000-0002-4794-3693 and Stricker, Sigmar ORCID: https://orcid.org/0000-0002-7174-5363
Nature Communications 17 (1): 286. 8 January 2026

2025

Generation of cirVDJseq libraries from 3’-barcoded cDNA v1.
Plumbom, Izabela ORCID: https://orcid.org/0009-0006-3720-3700, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X and Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295
protocols.io : protocols.io.q26g77zx1gwz/v1. 17 December 2025

AP1 is a pioneer transcription factor that programmes cell fate through MADS-domain protein tetramerisation.
Xu, Xiaocai ORCID: https://orcid.org/0000-0002-2972-4251, Neumann, Manuel ORCID: https://orcid.org/0000-0002-7883-0843, Carew, Frederic ORCID: https://orcid.org/0009-0003-8387-7149, Chen, Peilin ORCID: https://orcid.org/0000-0002-0498-8349, Braeuning, Caroline ORCID: https://orcid.org/0009-0007-1439-9920, Zubieta, Chloe ORCID: https://orcid.org/0000-0003-4558-9333, Muino, Jose M. ORCID: https://orcid.org/0000-0002-6403-7262, Smaczniak, Cezary ORCID: https://orcid.org/0000-0002-4663-8275 and Kaufmann, Kerstin ORCID: https://orcid.org/0000-0001-7960-6256
Genome Biology 26 (1): 418. 9 December 2025

The dorsal aortic compartment is a developmental source of brown adipose tissue in mice.
Secener, Kerim ORCID: https://orcid.org/0000-0003-4806-2852, Pöhle-Kronawitter, Sophie, Fischer, Cornelius ORCID: https://orcid.org/0000-0003-0329-2435, Vallecillo García, Pedro, Kotsaris, Georgios, Pawolski, Verena, Giesecke-Thiel, Claudia, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Schulz, Tim J., Sauer, Sascha ORCID: https://orcid.org/0000-0002-4794-3693 and Stricker, Sigmar
[Dataset] 2 December 2025

The deubiquitinase OTUD7B ameliorates central nervous system autoimmunity by inhibiting degradation of glial fibrillary acidic protein and astrocyte hyperinflammation.
Harit, K., Yi, W., Jeron, A., Schmidt, J., Beckervordersandfort-Bonk, R., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Plumbon, I., Manukyan, A. ORCID: https://orcid.org/0000-0002-0441-9517, Deckert, M., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Wang, X., Nishanth, G. and Schlüter, D.
[Dataset] 1 December 2025

Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation.
Harit, Kunjan, Yi, Wenjing, Jeron, Andreas, Schmidt, Jakob, Beckervordersandforth, Ruth ORCID: https://orcid.org/0000-0002-3617-7567, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Manukyan, Artür ORCID: https://orcid.org/0000-0002-0441-9517, Deckert, Martina, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Altmüller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Wang, Xu ORCID: https://orcid.org/0000-0001-8428-9339, Nishanth, Gopala ORCID: https://orcid.org/0000-0002-7280-5663 and Schlüter, Dirk ORCID: https://orcid.org/0000-0003-1478-3328
Nature Communications 16 (1): 9279. 20 October 2025

Extended supplementary data for manuscript: Gene regulatory mechanisms of cellular memory of a single cocaine exposure in VTA dopaminergic neurons.
Zea-Redondo, Luna ORCID: https://orcid.org/0000-0001-9064-9126, Franke, Vedran ORCID: https://orcid.org/0000-0003-3606-6792, Paul, Eleanor J., Kukalev, Alexander ORCID: https://orcid.org/0000-0001-5847-3773, Arguedas Jimenez, Laura ORCID: https://orcid.org/0009-0004-2240-7781, Braeuning, Caroline ORCID: https://orcid.org/0009-0007-1439-9920, Marin, Oscar, Akalin, Altuna ORCID: https://orcid.org/0000-0002-0468-0117, Ungless, Mark A., Winick-Ng, Warren ORCID: https://orcid.org/0000-0002-8716-5558 and Pombo, Ana ORCID: https://orcid.org/0000-0002-7493-6288
[Dataset] 4 September 2025

Cellular dynamics and epidermal specialization during Arabidopsis floral development at single-cell resolution.
Chen, Siye ORCID: https://orcid.org/0009-0001-3521-5955, Neumann, Manuel ORCID: https://orcid.org/0000-0002-7883-0843, He, Zhaohui ORCID: https://orcid.org/0000-0002-8976-9494, Carew, Frederic ORCID: https://orcid.org/0009-0003-8387-7149, Smaczniak, Cezary ORCID: https://orcid.org/0000-0002-4663-8275, Braeuning, Caroline ORCID: https://orcid.org/0009-0007-1439-9920, Richter, Sarah, Zhang, Yingjue ORCID: https://orcid.org/0009-0001-7787-131X, Zhou, Xinkai ORCID: https://orcid.org/0000-0001-8791-294X and Kaufmann, Kerstin ORCID: https://orcid.org/0000-0001-7960-6256
bioRxiv : 2025.09.01.672611. 1 September 2025

A clinically relevant morpho-molecular classification of lung neuroendocrine tumours.
Sexton-Oates, Alexandra, Mathian, Emilie, Candeli, Noah, Lim, Yuliya, Voegele, Catherine ORCID: https://orcid.org/0000-0002-9592-8869, Di Genova, Alex ORCID: https://orcid.org/0000-0002-3120-9283, Mange, Laurane ORCID: https://orcid.org/0009-0007-8560-1364, Li, Zhaozhi, van Weert, Tijmen, Hillen, Lisa M., Blazquez-Encinas, Ricardo, Gonzalez-Perez, Abel, Morrison, Maike L. ORCID: https://orcid.org/0000-0003-0430-1401, Lauricella, Eleonora, Mangiante, Lise ORCID: https://orcid.org/0000-0001-8309-0950, Bonheme, Lisa, Moonen, Laura, Absenger, Gudrun, Altmuller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Degletagne, Cyril, Brustugun, Odd Terje, Cahais, Vincent, Centonze, Giovanni, Chabrier, Amelie, Cuenin, Cyrille, Damiola, Francesca, de Montpreville, Vincent Thomas, Deleuze, Jean-Francois, Dingemans, Anne-Marie C., Fadel, Elie, Gadot, Nicolas, Ghantous, Akram, Graziano, Paolo, Hofman, Paul, Hofman, Veronique, Ibanez-Costa, Alejandro, Lacomme, Stephanie, Lopez-Bigas, Nuria, Lund-Iversen, Marius, Milione, Massimo, Muscarella, Lucia Anna, Pedraza-Arevalo, Sergio, Perrin, Corinne, Planchard, Gaetane, Popper, Helmut, Roz, Luca, Sparaneo, Angelo, Buikhuisen, Wieneke ORCID: https://orcid.org/0000-0002-0799-7187, Van den Berg, Jose, Tesselaar, Margot, Kim, Jaehee, Speel, Ernst-Jan M., Tabone-Eglinger, Severine, Walter, Thomas, Wright, Gavin, Castano, Justo P., Chalabreysse, Lara, Chen, Liming, Caux, Christophe, Volante, Marco, Girard, Nicolas, Vignaud, Jean-Michel, Conde, Esther, Mansuet-Lupo, Audrey ORCID: https://orcid.org/0000-0002-7196-2114, Brcic, Luka ORCID: https://orcid.org/0000-0002-9098-8416, Pelosi, Giuseppe ORCID: https://orcid.org/0000-0003-4725-4692, Papotti, Mauro, Lantuejoul, Sylvie, Derks, Jules, Dayton, Talya ORCID: https://orcid.org/0000-0002-7994-7963, Alcala, Nicolas ORCID: https://orcid.org/0000-0002-5961-5064, Foll, Matthieu ORCID: https://orcid.org/0000-0001-9006-8436 and Fernandez-Cuesta, Lynnette ORCID: https://orcid.org/0000-0002-9290-4589
medRxiv : 2025.07.18.25331556. 18 July 2025

Factor-H-related protein 1 (FHR1), a promotor of para-inflammation in age-related macular degeneration.
Sekulic, Andjela, Herr, Sarah M., Mulfaul, Kelly, Pompös, Inga-Marie ORCID: https://orcid.org/0000-0001-9314-8378, Winkler, Silvia, Dietrich, Carola, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Mullins, Robert F., Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Zipfel, Peter F., Sennlaub, Florian, Skerka, Christine and Strauß, Olaf
Journal of Neuroinflammation 22 (1): 173. 3 July 2025

Mapping CD4+ T cell diversity in CSF to identify endophenotypes of multiple sclerosis.
Crowley, T. ORCID: https://orcid.org/0000-0002-1404-6005, Chen, J. ORCID: https://orcid.org/0000-0002-4355-4121, Rosiewicz, K.S. ORCID: https://orcid.org/0000-0002-6926-7227, Jopp-Saile, L. ORCID: https://orcid.org/0000-0002-7032-3003, Herold, G., Biese, C., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Kerkering, J. ORCID: https://orcid.org/0000-0002-6432-7104, Alisch, M. ORCID: https://orcid.org/0009-0000-8316-6193, Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070 and Siffrin, V. ORCID: https://orcid.org/0000-0002-1532-2868
Brain Communications 7 (3): fcaf231. 19 June 2025

A macrophage-predominant immunosuppressive microenvironment and therapeutic vulnerabilities in advanced salivary gland cancer.
Zuljan, E., von der Emde, B., Piwonski, I., Pestana, A., Klinghammer, K. ORCID: https://orcid.org/0000-0001-6425-4833, Mock, A. ORCID: https://orcid.org/0000-0002-3332-9166, Horak, P. ORCID: https://orcid.org/0000-0003-4536-9306, Heining, C., Klauschen, F. ORCID: https://orcid.org/0000-0002-9131-2389, Pretzell, I., Boerries, M. ORCID: https://orcid.org/0000-0002-3670-0602, Brandts, C.H., Kreutzfeldt, S. ORCID: https://orcid.org/0000-0003-3278-4586, Teleanu, M.V., Hübschmann, D. ORCID: https://orcid.org/0000-0002-6041-7049, Morris, L.G.T. ORCID: https://orcid.org/0000-0002-4417-2280, Heiland, M. ORCID: https://orcid.org/0000-0002-4987-2913, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Glimm, H. ORCID: https://orcid.org/0000-0003-4104-1135, Fröhling, S. ORCID: https://orcid.org/0000-0001-7907-4595, Ochsenreither, S. ORCID: https://orcid.org/0000-0001-6024-4312, Keilholz, U., Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632 and Rieke, D.T. ORCID: https://orcid.org/0000-0003-0027-7977
Nature Communications 16 (1): 5303. 12 June 2025

The IL-22–oncostatin M axis promotes intestinal inflammation and tumorigenesis.
Cineus, R. ORCID: https://orcid.org/0000-0003-4393-5757, Luo, Y. ORCID: https://orcid.org/0009-0003-0401-467X, Saliutina, M., Manna, S. ORCID: https://orcid.org/0000-0003-2360-0618, Cancino, C.A., Velasco Blázquez, L., Wang, L., Bösel, D., Abdelrahman, A., Klementowicz, J.E., Scherl, A., Hainbuch, S., Bréart, B., Kwon, G., Konopka, A., Guerra, G.M., von Coburg, E. ORCID: https://orcid.org/0009-0001-8546-8854, Gerbeth, Lo., Roels, J., Heinrich, F. ORCID: https://orcid.org/0000-0001-6097-5422, Müller, N. ORCID: https://orcid.org/0000-0003-1559-7711, Durek, P. ORCID: https://orcid.org/0000-0002-6179-0670, Deigendesch, N. ORCID: https://orcid.org/0000-0002-6036-3327, Ziai, J., Hung, J., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Kühl, A.A. ORCID: https://orcid.org/0000-0003-2293-5387, Wirtz, S. ORCID: https://orcid.org/0000-0001-6936-7431, Löhning, M. ORCID: https://orcid.org/0000-0001-6382-7281, Keir, M. ORCID: https://orcid.org/0000-0002-0637-4092, Diefenbach, A. ORCID: https://orcid.org/0000-0002-9176-9530, Mashreghi, M.F. ORCID: https://orcid.org/0000-0002-8015-6907, Siegmund, B. ORCID: https://orcid.org/0000-0002-0055-958X, Schumann, M., Romagnani, C. ORCID: https://orcid.org/0000-0002-5167-7463, West, N.R. and Hegazy, A.N. ORCID: https://orcid.org/0000-0002-2946-8251
Nature Immunology 26 (6): 837-853. June 2025

SEC24C deficiency causes trafficking and glycosylation abnormalities in an epileptic encephalopathy with cataracts and dyserythropoeisis.
Bögershausen, N., Cavdarli, B., Nagai, T., Milev, M.P., Wolff, A., Mehranfar, M., Schmidt, J., Choudhary, D., Gutiérrez-Gutiérrez, Ó., Cyganek, L., Saint-Dic, D., Zibat, A., Köhrer, K., Wollenweber, T.E., Wieczorek, D., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Kaçar, D., Haliloğlu, G., Li, Y., Thiel, C., Sacher, M., Knapik, E.W., Yigit, G. and Wollnik, B.
JCI Insight 10 (9): e173484. 8 May 2025

Senescent syncytiotrophoblast secretion during early onset preeclampsia.
Nonn, O. ORCID: https://orcid.org/0000-0001-6385-2866, Debnath, O. ORCID: https://orcid.org/0009-0009-2845-055X, Valdes, D.S. ORCID: https://orcid.org/0000-0002-1309-5147, Sallinger, K., Secener, A.K. ORCID: https://orcid.org/0000-0003-4806-2852, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Tiesmeyer, S. ORCID: https://orcid.org/0000-0002-0492-1523, Nimo, J. ORCID: https://orcid.org/0000-0002-1565-7799, Kuenzer, T. ORCID: https://orcid.org/0000-0001-6882-1217, Ulrich, J., Maxian, T. ORCID: https://orcid.org/0000-0002-8009-8479, Knöfler, M., Karau, P. ORCID: https://orcid.org/0000-0001-6590-1975, Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Kroneis, T. ORCID: https://orcid.org/0000-0002-4761-9340, Frolova, A. ORCID: https://orcid.org/0000-0001-5469-7366, Neuper, L., Haase, N. ORCID: https://orcid.org/0000-0003-0727-1738, Malt, A. ORCID: https://orcid.org/0009-0005-4049-0846, Müller-Bötticher, N. ORCID: https://orcid.org/0000-0001-5103-7282, Kräker, K. ORCID: https://orcid.org/0000-0002-4032-5382, Kedziora, S. ORCID: https://orcid.org/0000-0003-0124-2557, Forstner, D. ORCID: https://orcid.org/0000-0001-5451-7580, Eils, R., Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530, Haider, S. ORCID: https://orcid.org/0000-0003-2409-1317, Verlohren, S. ORCID: https://orcid.org/0000-0003-3507-8636, Stern, C. ORCID: https://orcid.org/0000-0002-6330-1236, Sugulle, M. ORCID: https://orcid.org/0000-0003-4160-3978, Jones, S. ORCID: https://orcid.org/0000-0002-3106-6155, Thilaganathan, B. ORCID: https://orcid.org/0000-0002-5531-4301, Kaitu'u-Lino, T.J. ORCID: https://orcid.org/0000-0001-6233-9737, Tong, S., Huppertz, B. ORCID: https://orcid.org/0000-0003-4814-2158, El-Heliebi, A. ORCID: https://orcid.org/0000-0002-7679-6856, Staff, A.C. ORCID: https://orcid.org/0000-0001-9247-5721, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Gauster, M. ORCID: https://orcid.org/0000-0003-0386-6857, Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X and Herse, F. ORCID: https://orcid.org/0000-0002-9305-8134
Hypertension 82 (5): 787-799. May 2025

UBE3C links ubiquitin signaling to epitranscriptomic control of cortical neurogenesis.
Borisova, Ekaterina, Cuthill, Katherine J. ORCID: https://orcid.org/0000-0003-3328-3249, Dannenberg, Rike, Koch, Janina, Nowaczyk, Julius ORCID: https://orcid.org/0009-0009-7068-4958, Schaub, Theres, Schwark, Manuela ORCID: https://orcid.org/0009-0008-1711-457X, Kastelic, N., Kupryianchyk-Schultz, I. ORCID: https://orcid.org/0009-0007-6442-4469, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Pentimalli, T.M. ORCID: https://orcid.org/0000-0002-8461-7918, Fokkens, T.J. ORCID: https://orcid.org/0009-0005-4689-4024, Stein, F., Dietrich, C., Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Schwefel, D. ORCID: https://orcid.org/0000-0002-2945-0908, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Rybak-Wolf, A. ORCID: https://orcid.org/0000-0002-1192-5290, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Haberkant, P. ORCID: https://orcid.org/0000-0002-5608-9062, Lorenz, S. ORCID: https://orcid.org/0000-0002-9639-2381, Brose, N. ORCID: https://orcid.org/0000-0003-0938-8534, Kawabe, H. ORCID: https://orcid.org/0000-0001-5650-8696, Tarabykin, V. ORCID: https://orcid.org/0000-0001-8931-7263 and Ambrozkiewicz, M.C. ORCID: https://orcid.org/0000-0001-5225-5230
bioRxiv : 2025.04.09.646620v2. 29 April 2025

Interleukin-12 signaling drives Alzheimer’s disease pathology through disrupting neuronal and oligodendrocyte homeostasis.
Schneeberger, S., Kim, S.J. ORCID: https://orcid.org/0000-0001-8357-0073, Geesdorf, M.N., Friebel, E. ORCID: https://orcid.org/0000-0003-1419-2376, Eede, P., Jendrach, M. ORCID: https://orcid.org/0000-0002-8601-2277, Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Braeuning, C. ORCID: https://orcid.org/0009-0007-1439-9920, Ruhwedel, T. ORCID: https://orcid.org/0000-0002-9535-9395, Hülsmeier, A.J. ORCID: https://orcid.org/0000-0001-6987-8979, Gimber, N. ORCID: https://orcid.org/0000-0001-9456-3063, Foerster, M., Obst, J., Andreadou, M. ORCID: https://orcid.org/0000-0001-6757-4664, Mundt, S. ORCID: https://orcid.org/0000-0003-2169-2109, Schmoranzer, J., Prokop, S., Kessler, W., Kuhlmann, T., Möbius, W. ORCID: https://orcid.org/0000-0002-2902-7165, Nave, K.A. ORCID: https://orcid.org/0000-0001-8724-9666, Hornemann, T. ORCID: https://orcid.org/0000-0002-4218-1087, Becher, B. ORCID: https://orcid.org/0000-0002-1541-7867, Edgar, J.M. ORCID: https://orcid.org/0000-0002-3869-0962, Karaiskos, N. ORCID: https://orcid.org/0000-0001-7771-3947, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Heppner, F.L. ORCID: https://orcid.org/0000-0001-9816-8917
Nature Aging 5 (4): 622-641. April 2025

Rapid brain tumor classification from sparse epigenomic data.
Brändl, B. ORCID: https://orcid.org/0000-0003-1044-1355, Steiger, M. ORCID: https://orcid.org/0000-0002-3747-685X, Kubelt, C., Rohrandt, C., Zhu, Z. ORCID: https://orcid.org/0000-0003-3779-4265, Evers, M., Wang, G., Schuldt, B., Afflerbach, A.K., Wong, D., Lum, A., Halldorsson, S., Djirackor, L., Leske, H., Magadeeva, S., Smičius, R., Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Schmidt, N.O., Schüller, U. ORCID: https://orcid.org/0000-0002-8731-1121, Vik-Mo, E.O. ORCID: https://orcid.org/0000-0001-8303-4123, Proescholdt, M., Riemenschneider, M.J., Zadeh, G. ORCID: https://orcid.org/0000-0002-6637-4502, Ammerpohl, O., Yip, S. ORCID: https://orcid.org/0000-0002-8514-9861, Synowitz, M., van Bömmel, A. ORCID: https://orcid.org/0000-0002-8434-8586, Kretzmer, H. ORCID: https://orcid.org/0000-0002-0723-4980 and Müller, F.J. ORCID: https://orcid.org/0000-0001-9478-8430
Nature Medicine 31 (3): 840-848. March 2025

Formation of amyloid-like HTTex1 aggregates in neurons, downregulation of synaptic proteins and early mortality of Huntington's disease flies are causally linked.
Ast, A. ORCID: https://orcid.org/0000-0002-2312-1257, Roth, L., Brusendorf, L., Schindler, F. ORCID: https://orcid.org/0000-0002-3320-8284, Ammar, O.W.M. ORCID: https://orcid.org/0009-0003-5341-4434, Berberich, S., Edel, J., Bonsor, M. ORCID: https://orcid.org/0000-0001-5447-084X, Georgii, E., Hänig, C. ORCID: https://orcid.org/0000-0003-1973-7646, Langnick, C., Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Piraud, M., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Petzoldt, A.G. and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
bioRxiv : 2025.02.06.636778. 7 February 2025

Esophageal adenocarcinoma relapse after chemoradiation is dominated by a basal-like subtype.
Hoppe, S., Noseir, S., Yazbeck, A., Zaburannyi, N., Grossbach, J., Lyu, S.I., Velazquez Camacho, O., Müller, S., Gebauer, F., Richartz, V., Holz, B., Berg, J., Achter, V., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Becker, K., Arolt, C., Meder, L., Zhao, Y., Schlößer, H., Baus, W.W., Kamp, F., Baues, C., Beyer, A. ORCID: https://orcid.org/0000-0002-3891-2123, Odenthal, M., Quaas, A., Buettner, R. and Hillmer, A.M. ORCID: https://orcid.org/0000-0002-3381-7266
bioRxiv : 2025.01.28.635332. 1 February 2025

Genetic alterations, therapy response, and survival among patients with triple-negative breast cancer: a secondary analysis of a randomized clinical trial.
Richters, L., Gluz, O., Weber-Lassalle, N., Christgen, M., Haverkamp, H., Kuemmel, S., Kayali, M., Kates, R.E., Grischke, E.M., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Forstbauer, H., Thiele, H., Braun, M., Warm, M., Ossowski, A., Wuerstlein, R., Ernst, C., Graeser, M., Linn, S.C., Nitz, U., Hauke, J., Kreipe, H.H., Schmutzler, R.K., Hahnen, E. and Harbeck, N.
JAMA Network Open 8 (2): e2461639. February 2025

Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4(+) T cells as predictors for response to integrin α4β7-blocking therapy in inflammatory bowel disease.
Horn, V., Cancino, C.A., Steinheuer, L.M., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Fritz, K., Nguyen, A.L., Juhran, K.S., Plattner, C., Bösel, D., Oldenburg, L., Burns, M., Schulz, A.R., Saliutina, M., Mantzivi, E., Lissner, D., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Mashreghi, M.F., Zundler, S., Sonnenberg, E., Schumann, M., Haag, L.M., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Flatz, L., Trjanoski, Z., D'Haens, G., Weidinger, C., Mei, H.E., Siegmund, B., Thurley, K. and Hegazy, A.N.
Gastroenterology 168 (2): 327-343. February 2025

TERT expression and clinical outcome in pulmonary carcinoids.
Werr, L. ORCID: https://orcid.org/0000-0002-3697-4136, Bartenhagen, C. ORCID: https://orcid.org/0000-0002-2522-1454, Rosswog, C. ORCID: https://orcid.org/0000-0002-8855-6198, Cartolano, M., Voegele, C. ORCID: https://orcid.org/0000-0002-9592-8869, Sexton-Oates, A., Di Genova, A. ORCID: https://orcid.org/0000-0002-3120-9283, Ernst, A. ORCID: https://orcid.org/0000-0003-2375-1889, Kahlert, Y. ORCID: https://orcid.org/0009-0006-0556-0439, Hemstedt, N., Höppner, S. ORCID: https://orcid.org/0000-0002-2318-1874, Mansuet Lupo, A. ORCID: https://orcid.org/0000-0002-7196-2114, Pelosi, G. ORCID: https://orcid.org/0000-0003-4725-4692, Brcic, L. ORCID: https://orcid.org/0000-0002-9098-8416, Papotti, M., George, J., Bosco, G., Quaas, A., Tang, L.H., Robzyk, K., Kadota, K., Roh, M.S., Fanaroff, R.E. ORCID: https://orcid.org/0009-0000-1451-000X, Falcon, C.J. ORCID: https://orcid.org/0000-0001-9143-1639, Büttner, R. ORCID: https://orcid.org/0000-0001-8806-4786, Lantuejoul, S., Rekhtman, N. ORCID: https://orcid.org/0000-0001-5801-3144, Rudin, C.M. ORCID: https://orcid.org/0000-0001-5204-3465, Travis, W.D., Alcala, N. ORCID: https://orcid.org/0000-0002-5961-5064, Fernandez-Cuesta, L., Foll, M. ORCID: https://orcid.org/0000-0001-9006-8436, Peifer, M. ORCID: https://orcid.org/0000-0002-5243-5503, Thomas, R.K. and Fischer, M. ORCID: https://orcid.org/0000-0003-1363-1242
Journal of Clinical Oncology 43 (2): 214-225. 10 January 2025

Design and characterization of G-quadruplex RNA aptamers reveal RNA-binding by KDM5 lysine demethylases.
Luige, J. ORCID: https://orcid.org/0000-0003-1314-8103, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Armaos, A., Louloupi, A. ORCID: https://orcid.org/0000-0003-3729-9002, Vincent, A., Meierhofer, D. ORCID: https://orcid.org/0000-0002-0170-868X, Gajhede, M., Tartaglia, G.G. and Ørom, U.A.V. ORCID: https://orcid.org/0000-0002-0643-0592
Computational and Structural Biotechnology Journal 27 : 2719-2729. 2025

2024

Circulating tumor DNA sequencing for biologic classification and individualized risk stratification in patients with Hodgkin Lymphoma.
Heger, J.M. ORCID: https://orcid.org/0000-0001-9463-8504, Mammadova, L., Mattlener, J. ORCID: https://orcid.org/0000-0001-7048-0351, Sobesky, S., Cirillo, M. ORCID: https://orcid.org/0000-0001-9881-0260, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Kirst, E., Reinke, S., Klapper, W., Bröckelmann, P.J. ORCID: https://orcid.org/0000-0001-9662-9900, Ferdinandus, J. ORCID: https://orcid.org/0000-0002-3481-7997, Kaul, H., Schneider, G. ORCID: https://orcid.org/0000-0001-6175-2554, Schneider, J. ORCID: https://orcid.org/0000-0001-7163-819X, Schleifenbaum, J.K. ORCID: https://orcid.org/0000-0001-7204-3235, Ullrich, R.T., Freihammer, M., Awerkiew, S. ORCID: https://orcid.org/0000-0001-5739-319X, Lohmann, M., Klein, F. ORCID: https://orcid.org/0000-0003-1376-1792, Nürnberg, P. ORCID: https://orcid.org/0000-0002-7228-428X, Hallek, M. ORCID: https://orcid.org/0000-0002-7425-4455, Rossi, D. ORCID: https://orcid.org/0000-0002-2837-1597, Mauz-Körholz, C. ORCID: https://orcid.org/0000-0002-8205-8665, Gattenlöhner, S., Bräuninger, A., Borchmann, P. ORCID: https://orcid.org/0000-0003-3782-2158, von Tresckow, B. ORCID: https://orcid.org/0000-0003-1410-4487 and Borchmann, S.
Journal of Clinical Oncology 42 (35): 4218-4230. 10 December 2024

Effective inhibitor removal from wastewater samples increases sensitivity of RT-dPCR and sequencing analyses and enhances the stability of wastewater-based surveillance.
Linzner, N., Bartel, A. ORCID: https://orcid.org/0000-0002-1280-6138, Schumacher, V., Grau, J.H. ORCID: https://orcid.org/0000-0002-5328-3652, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Preuß, H., Garske, S., Bitzegeio, J., Kirst, E.B., Liere, K. ORCID: https://orcid.org/0000-0003-1504-1449, Hoppe, S., Borodina, T.A. ORCID: https://orcid.org/0000-0002-6978-016X, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Meixner, M., Sagebiel, D. and Böckelmann, U.
Microorganisms 12 (12): 2475. December 2024

Heat stress causes chromatin accessibility and related gene expression changes in crown tissues of barley (Hordeum vulgare).
Kiełbowicz-Matuk, A., Smaczniak, C., Mikołajczak, K., Kuczyńska, A., Xu, X., Braeuning, C. ORCID: https://orcid.org/0009-0007-1439-9920 and Krajewski, P. ORCID: https://orcid.org/0000-0001-5318-9896
Plant Molecular Biology 114 (6): 115. 22 October 2024

Spatiotemporal transcriptomic mapping of regenerative inflammation in skeletal muscle reveals a dynamic multilayered tissue architecture.
Patsalos, A., Halasz, L., Oleksak, D., Wei, X., Nagy, G., Tzerpos, P., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Hammers, D.W., Sweeney, H.L. and Nagy, L.
Journal of Clinical Investigation 134 (20): e173858. 15 October 2024

Intercellular extrachromosomal DNA copy-number heterogeneity drives neuroblastoma cell state diversity.
Stöber, M.C., Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Wittstruck, N. ORCID: https://orcid.org/0009-0000-4378-3226, Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Eggert, A., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Koche, R.P., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268 and Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618
Cell Reports 43 (9): 114711. 24 September 2024

A homozygous nonsense mutation identified in COL7A1 in a family with autosomal recessive dystrophic epidermolysis bullosa.
Ayub, M., Xiong, X., Anwer, S., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Naeem, M., Hassan, N., Khan, K., Motameny, S., Khaliq, S., Rehman, F.U., Uddin, S.A., Wali, A., Betz, R. and Basit, S.
Journal of Medicine and Life 17 (9): 892-896. 9 September 2024

Intramyocardial sprouting tip cells specify coronary arterialization.
Cano, E. ORCID: https://orcid.org/0000-0003-1091-8934, Schwarzkopf, J. ORCID: https://orcid.org/0000-0001-9552-0794, Kanda, M. ORCID: https://orcid.org/0000-0003-3468-3586, Lindberg, E.L. ORCID: https://orcid.org/0000-0002-2979-433X, Hollfinger, I. ORCID: https://orcid.org/0000-0002-6233-8395, Pogontke, C. ORCID: https://orcid.org/0000-0002-9610-9822, Braeuning, C. ORCID: https://orcid.org/0009-0007-1439-9920, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Circulation Research 135 (6): 671-684. 30 August 2024

Pathogen dynamics and discovery of novel viruses and enzymes by deep nucleic acid sequencing of wastewater.
Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Lauber, C., Manukyan, A. ORCID: https://orcid.org/0000-0002-0441-9517, Deter, A., Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Wylezich, C. ORCID: https://orcid.org/0000-0002-0436-4480, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Seitz, S., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521 and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
Environment International 190 : 108875. August 2024

Single-nucleus and spatial transcriptome reveal adrenal homeostasis in normal and tumoural adrenal glands.
Altieri, B. ORCID: https://orcid.org/0000-0003-2616-3249, Secener, A.K. ORCID: https://orcid.org/0000-0003-4806-2852, Sai, S. ORCID: https://orcid.org/0000-0001-6865-341X, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Sbiera, S., Arampatzi, P., Kircher, S., Herterich, S., Landwehr, L.S., Vitcetz, S.N., Braeuning, C. ORCID: https://orcid.org/0009-0007-1439-9920, Fassnacht, M. ORCID: https://orcid.org/0000-0001-6170-6398, Ronchi, C.L. ORCID: https://orcid.org/0000-0001-5020-2071 and Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693
Clinical and Translational Medicine 14 (8): e1798. August 2024

Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome.
Busley, A.V., Gutiérrez-Gutiérrez, Ó., Hammer, E., Koitka, F., Mirzaiebadizi, A., Steinegger, M., Pape, C., Böhmer, L., Schroeder, H., Kleinsorge, M., Engler, M., Cirstea, I.C., Gremer, L., Willbold, D., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Marbach, F., Hasenfuss, G., Zimmermann, W.H., Ahmadian, M.R., Wollnik, B. and Cyganek, L.
Cell Reports 43 (7): 114448. 23 July 2024

In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia.
Bakina, O. ORCID: https://orcid.org/0000-0002-3486-9906, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Mitic, N. ORCID: https://orcid.org/0000-0003-0141-1293, Vidal, R.O. ORCID: https://orcid.org/0000-0003-4217-2014, Obrusnik, T., Sai, S. ORCID: https://orcid.org/0000-0001-6865-341X, Nolte, C. ORCID: https://orcid.org/0000-0001-5398-3440, Semtner, M. ORCID: https://orcid.org/0000-0001-9379-9023 and Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291
PLoS ONE 19 (7): e0302376. 11 July 2024

Diagnosing recipient- vs. donor-derived posttransplant myelodysplastic neoplasm via targeted single-cell mutational profiling.
Ihlow, J., Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207, Vuong, L.G., Bischoff, P., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Trinks, A. ORCID: https://orcid.org/0000-0001-9983-1506, Blau, O., Behnke, A., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Morkel, M. ORCID: https://orcid.org/0000-0002-2553-9999, Wu, C.J., Westermann, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, von Brünneck, A.C., Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447, Horst, D. and Praktiknjo, S.D. ORCID: https://orcid.org/0000-0002-0186-5271
Med 6 (4): 100548. 11 April 2024

T- and L-type calcium channels maintain calcium oscillations in the murine zona glomerulosa.
Dinh, H.A. ORCID: https://orcid.org/0000-0002-7367-997X, Volkert, M., Secener, A.K. ORCID: https://orcid.org/0000-0003-4806-2852, Scholl, U.I. ORCID: https://orcid.org/0000-0002-0309-8045 and Stölting, G. ORCID: https://orcid.org/0000-0002-2339-0545
Hypertension 81 (4): 811-822. April 2024

Activation of gp130 signaling in T cells drives T(H)17-mediated multi-organ autoimmunity.
Baumgartner, F. ORCID: https://orcid.org/0000-0003-0768-1956, Bamopoulos, S.A. ORCID: https://orcid.org/0000-0002-5997-7735, Faletti, L. ORCID: https://orcid.org/0000-0002-9213-2478, Hsiao, H.J., Holz, M. ORCID: https://orcid.org/0009-0002-1294-8205, Gonzalez-Menendez, I., Solé-Boldo, L. ORCID: https://orcid.org/0000-0002-6974-9066, Horne, A. ORCID: https://orcid.org/0000-0002-4209-4573, Gosavi, S., Özerdem, C. ORCID: https://orcid.org/0000-0001-6772-0422, Singh, N., Liebig, S. ORCID: https://orcid.org/0000-0002-5494-8476, Ramamoorthy, S. ORCID: https://orcid.org/0000-0003-3468-4247, Lehmann, M. ORCID: https://orcid.org/0000-0002-3786-7375, Demel, U. ORCID: https://orcid.org/0000-0002-6480-4185, Kühl, A.A. ORCID: https://orcid.org/0000-0003-2293-5387, Wartewig, T. ORCID: https://orcid.org/0000-0001-8699-1690, Ruland, J. ORCID: https://orcid.org/0000-0002-8381-3597, Wunderlich, F.T. ORCID: https://orcid.org/0000-0002-9209-3501, Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Rose-John, S. ORCID: https://orcid.org/0000-0002-7519-3279, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Quintanilla-Martinez, L., Feske, S., Ehl, S. ORCID: https://orcid.org/0000-0002-9265-2721, Glauben, R. ORCID: https://orcid.org/0000-0003-2889-2525 and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
Science Signaling 17 (824): eadc9662. 20 February 2024

The role of microRNAs in defining LSECs cellular identity and in regulating F8 gene expression.
Jamil, M. A., Al-Rifai, R., Nuesgen, N., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Oldenburg, J. and El-Maarri, O.
Frontiers in Genetics 15 : 1302685. 19 February 2024

SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells.
Kalnytska, O. ORCID: https://orcid.org/0009-0005-8276-3849, Qvist, P., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921 and Schmidt, V. ORCID: https://orcid.org/0000-0002-5851-1087
iScience 27 (1): 108725. 19 January 2024

Interferon regulatory factor 4 plays a pivotal role in the development of aGVHD-associated colitis.
Frueh, J.T., Campe, J., Sunaga-Franze, D.Y. ORCID: https://orcid.org/0000-0002-6851-9162, Verheyden, N.A., Ghimire, S., Meedt, E., Haslinger, D., Harenkamp, S., Staudenraus, D., Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Kreft, A., Schubert, R., Lohoff, M., Krueger, A., Bonig, H., Chiocchetti, A.G., Zeiser, R., Holler, E. and Ullrich, E. ORCID: https://orcid.org/0000-0001-8530-1192
OncoImmunology 13 (1): 2296712. 2024

2023

Osteopontin in colitis-associated carcinoma.
Manna, S., Sehn, M., Cardoso da Silva, D., Wiese, J.J., Heldt, C., Plumbom, I. ORCID: https://orcid.org/0009-0006-3720-3700, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Husemann, C.C., Kleo, K., Derêzanin, L., Dony, V., Farahani, S.K., Weiss, F., Branchi, F., Kühl, A.A., Schallenberg, S., Weiner, J. ORCID: https://orcid.org/0000-0003-1438-7819, Elezkurtaj, S., Weixler, B., Gröne, J., Siegmund, B., Hummel, M. and Schumann, M.
bioRxiv : 2023.12.15.571952. 16 December 2023

VoltRon: a spatial omics analysis platform for multi-resolution and multi-omics integration using image registration.
Manukyan, A. ORCID: https://orcid.org/0000-0002-0441-9517, Bahry, E. ORCID: https://orcid.org/0000-0002-6358-2576, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Becher, E., Pascual-Reguant, Anna, Plumbom, I. ORCID: https://orcid.org/0009-0006-3720-3700, Dikmen, H.O., Elezkurtaj, S., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Hauser, A.E., Hocke, A., Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Schmidt, D. ORCID: https://orcid.org/0000-0002-8621-9438, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
bioRxiv : 2023.12.15.571667. 15 December 2023

XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes.
Chatzinikolaou, G. ORCID: https://orcid.org/0000-0002-0868-0683, Stratigi, K. ORCID: https://orcid.org/0000-0001-7476-6410, Siametis, A. ORCID: https://orcid.org/0000-0003-0668-7563, Goulielmaki, E. ORCID: https://orcid.org/0000-0003-1651-3137, Akalestou-Clocher, A. ORCID: https://orcid.org/0000-0002-1267-6054, Tsamardinos, I. ORCID: https://orcid.org/0000-0002-2492-959X, Topalis, P. ORCID: https://orcid.org/0000-0002-1635-4810, Austin, C., Bouwman, B.A.M. ORCID: https://orcid.org/0000-0002-9827-9497, Crosetto, N., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521 and Garinis, G.A. ORCID: https://orcid.org/0000-0002-3200-5004
Science Advances 9 (45): eadi2095. 10 November 2023

Spatial and single-cell profiling of the metabolome, transcriptome and epigenome of the aging mouse liver.
Nikopoulou, C. ORCID: https://orcid.org/0000-0001-7982-7737, Kleinenkuhnen, N., Parekh, S. ORCID: https://orcid.org/0000-0002-4826-1651, Sandoval, T., Ziegenhain, C. ORCID: https://orcid.org/0000-0003-2208-4877, Schneider, F., Giavalisco, P. ORCID: https://orcid.org/0000-0002-4636-1827, Donahue, K.F., Vesting, A.J., Kirchner, M. ORCID: https://orcid.org/0000-0003-0276-0495, Bozukova, M., Vossen, C., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Wunderlich, T. ORCID: https://orcid.org/0000-0002-9209-3501, Sandberg, R. ORCID: https://orcid.org/0000-0001-6473-1740, Kondylis, V. ORCID: https://orcid.org/0000-0002-6970-8731, Tresch, A. ORCID: https://orcid.org/0000-0002-4146-6371 and Tessarz, P. ORCID: https://orcid.org/0000-0002-6953-9835
Nature Aging 3 (11): 1430-1445. November 2023

NCBench: providing an open, reproducible, transparent, adaptable, and continuous benchmark approach for DNA-sequencing-based variant calling.
Hanssen, F., Gabernet, G., Smith, N.H. ORCID: https://orcid.org/0009-0008-0026-0757, Mertes, C., Neogi, A.G., Brandhoff, L., Ossowski, A., Altmueller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Becker, K., Petzold, A., Sturm, M., Stöcker, T., Sivalingam, S., Brand, F., Schmidt, A., Buness, A., Probst, A.J., Motameny, S. ORCID: https://orcid.org/0000-0003-1186-1108 and Köster, J. ORCID: https://orcid.org/0000-0001-9818-9320
F1000Research 12 : 1125. 11 September 2023

Potential contribution of ancient introgression to the evolution of a derived reproductive strategy in ricefishes.
Flury, J.M. ORCID: https://orcid.org/0000-0001-9994-5490, Meusemann, K., Martin, S., Hilgers, L., Spanke, T., Böhne, A. ORCID: https://orcid.org/0000-0002-1284-3115, Herder, F., Mokodongan, D., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Wowor, D., Misof, B., Nolte, A.W. and Schwarzer, J.
Genome Biology and Evolution 15 (8): evad138. 29 August 2023

Long-read sequencing identifies a common transposition haplotype predisposing for CLCNKB deletions.
Tschernoster, N. ORCID: https://orcid.org/0000-0002-6058-9342, Erger, F., Kohl, S., Reusch, B., Wenzel, A., Walsh, S., Thiele, H., Becker, C., Franitza, M., Bartram, M.P., Kömhoff, M., Schumacher, L., Kukat, C., Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Nürnberg, P., Rinschen, M.M., Driller, J.H., Pedersen, B.P., Schlingmann, K.P., Hüttel, B., Bockenhauer, D., Beck, B. and Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521
Genome Medicine 15 (1): 62. 23 August 2023

The interleukin-11 receptor variant p.W307R results in craniosynostosis in humans.
Ahmad, I., Lokau, J., Kespohl, B., Malik, N.A., Baig, S.M., Hartig, R., Behme, D., Schwab, R., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Jameel, M., Mucha, S., Thiele, H., Tariq, M., Nürnberg, P., Erdmann, J. and Garbers, C.
Scientific Reports 13 (1): 13479. 18 August 2023

Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
Sholokh, A. ORCID: https://orcid.org/0000-0002-1263-2078, Walter, S., Markó, L. ORCID: https://orcid.org/0000-0003-1888-5575, McMurray, B.J., Sunaga-Franze, D.Y. ORCID: https://orcid.org/0000-0002-6851-9162, Xu, M., Zühlke, K., Russwurm, M., Bartolomaeus, T.U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Langanki, R., Qadri, F. ORCID: https://orcid.org/0000-0002-8500-489X, Heuser, A. ORCID: https://orcid.org/0000-0002-3334-960X, Patzak, A., Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Bähring, S. ORCID: https://orcid.org/0000-0001-8734-9755, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Persson, P.B., Maass, P.G. ORCID: https://orcid.org/0000-0002-2742-8301, Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164 and Klussmann, E. ORCID: https://orcid.org/0000-0003-4004-5003
Kidney International 104 (2): 388-393. August 2023

Platelet-derived factors dysregulate placental sphingosine-1-phosphate receptor 2 in human trophoblasts.
Lyssy, F., Guettler, J. ORCID: https://orcid.org/0000-0002-8141-5712, Brugger, B.A., Stern, C., Forstner, D., Nonn, O. ORCID: https://orcid.org/0000-0001-6385-2866, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Herse, F., Wernitznig, S., Hirschmugl, B., Wadsack, C. and Gauster, M.
Reproductive BioMedicine Online 47 (2): 103215. August 2023

Ablation of collagen XII disturbs joint extracellular matrix organization and causes patellar subluxation.
Zhu, M., Metzen, F., Hopkinson, M., Betz, J., Heilig, J., Sodhi, J., Imhof, T., Niehoff, A., Birk, D.E., Izu, Y., Krüger, M., Pitsillides, A. A., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, van Osch, G.J.V.M., Straub, V., Schreiber, G., Paulsson, M., Koch, M. and Brachvogel, B.
iScience 26 (7): 107225. 21 July 2023

Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
Jiang, Q., Stachelscheid, J., Bloehdorn, J., Pacholewska, A., Aszyk, C.M., Grotenhuijs, F., Müller, T.A., Onder, O., Wagle, P., Herling, C.D., Kleppe, M., Wang, Z., Coombes, K.R., Robrecht, S., Dalvi, P.S., Plosnita, B., Mayer, P., Abruzzo, L.V., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Gathof, B.S., Persigehl, T., Fischer, K., Jebaraj, B.M.C., Rienhoff, H.Y., Ecker, R.C., Zhao, Y., Bruns, C.J., Stilgenbauer, S., Elenitoba-Johnson, K.S.J., Hallek, M., Schweiger, M.R., Odenthal, M., Vasyutina, E. and Herling, M.
Blood 142 (1): 44-61. 6 July 2023

iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
Kerkering, J. ORCID: https://orcid.org/0000-0002-6432-7104, Muinjonov, B. ORCID: https://orcid.org/0000-0002-9380-8038, Rosiewicz, K.S. ORCID: https://orcid.org/0000-0002-6926-7227, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Biese, C., Schiweck, J., Chien, C. ORCID: https://orcid.org/0000-0001-8280-9513, Zocholl, D., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070, Alisch, M. ORCID: https://orcid.org/0009-0000-8316-6193 and Siffrin, V. ORCID: https://orcid.org/0000-0002-1532-2868
Journal of Clinical Investigation 133 (13): e164637. 3 July 2023

A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation.
Vallecillo-García, P., Orgeur, M., Comai, G., Poehle-Kronnawitter, S., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Gloger, M. ORCID: https://orcid.org/0000-0002-3319-7642, Dumas, C.E., Giesecke-Thiel, C., Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Tajbakhsh, S., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Stricker, S.
Immunity 56 (6): 1204-1219. 13 June 2023

The phenotypic and genotypic spectrum of epilepsy and intellectual disability in adults: Implications for genetic testing.
von Brauchitsch, S., Haslinger, D., Lindlar, S., Thiele, H., Bernsen, N., Zahnert, F. ORCID: https://orcid.org/0000-0003-0366-6724, Reif, P.S., Balcik, Y., Au, P.Y.B., Josephson, C. ORCID: https://orcid.org/0000-0002-3607-834X, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Strzelczyk, A. ORCID: https://orcid.org/0000-0001-6288-9915, Knake, S., Rosenow, F., Chiocchetti, A. and Klein, K.M. ORCID: https://orcid.org/0000-0002-6654-1665
Epilepsia Open 8 (2): 497-508. June 2023

Germline C1GALT1C1 mutation causes a multisystem chaperonopathy.
Erger, F. ORCID: https://orcid.org/0000-0002-2768-1702, Aryal, R.P., Reusch, B., Matsumoto, Y. ORCID: https://orcid.org/0000-0003-2606-2616, Meyer, R., Zeng, J., Knopp, C., Noel, M., Muerner, L., Wenzel, A., Kohl, S., Tschernoster, N., Rappl, G., Rouvet, I., Schröder-Braunstein, J., Seibert, F.S., Thiele, H., Häusler, M.G., Weber, L.T. ORCID: https://orcid.org/0000-0003-4116-598X, Büttner-Herold, M., Elbracht, M., Cummings, S.F. ORCID: https://orcid.org/0000-0002-8918-5034, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Habbig, S., Cummings, R.D. and Beck, B.B. ORCID: https://orcid.org/0000-0003-0495-7670
Proceedings of the National Academy of Sciences of the United States of America 120 (22): e2211087120. 30 May 2023

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.
Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512, Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Beccaceci, G. ORCID: https://orcid.org/0000-0002-6453-3725, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, Li, H. ORCID: https://orcid.org/0000-0001-5677-3377, Liu, L. ORCID: https://orcid.org/0000-0002-9553-5475, Müllerke, S., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Heymann, F., Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Communications 14 (1): 3025. 25 May 2023

scEC(&)T-seq: a method for parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single human cells.
Chamorro González, Rocío ORCID: https://orcid.org/0000-0002-5653-7259, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Kasack, Katharina and Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X
Research Square. 23 May 2023

The fate of oxidative strand breaks in mitochondrial DNA.
Trombly, G., Said, A.M., Kudin, A.P., Peeva, V., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Becker, K., Köhrer, K. ORCID: https://orcid.org/0000-0003-3644-2022, Zsurka, G. ORCID: https://orcid.org/0000-0002-6379-849X and Kunz, W.S. ORCID: https://orcid.org/0000-0003-1113-3493
Antioxidants 12 (5): 1087. 12 May 2023

The genetic spectrum of congenital ocular motor apraxia type Cogan: an observational study, continued.
Schröder, S., Yigit, G., Li, Y., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Büttel, H.M., Fiedler, B., Kretzschmar, C., Nürnberg, P., Seeger, J., Serpieri, V., Valente, E.M., Wollnik, B., Boltshauser, E. and Brockmann, K. ORCID: https://orcid.org/0000-0001-6823-9091
Orphanet Journal of Rare Diseases 18 (1): 101. 2 May 2023

Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Stöber, M.C. ORCID: https://orcid.org/0000-0002-6679-5577, Xu, R. ORCID: https://orcid.org/0000-0002-5618-246X, Giurgiu, M. ORCID: https://orcid.org/0000-0001-5007-7442, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Kasack, K., Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, van Leen, E. ORCID: https://orcid.org/0000-0001-9545-4803, Helmsauer, K. ORCID: https://orcid.org/0000-0003-0773-4114, Dorado Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Stefanova, M.E. ORCID: https://orcid.org/0000-0002-4419-2839, Hung, K.L. ORCID: https://orcid.org/0000-0002-3662-4662, Bei, Y. ORCID: https://orcid.org/0000-0002-2104-8025, Schmelz, K., Lodrini, M., Mundlos, S., Chang, H.Y. ORCID: https://orcid.org/0000-0002-9459-4393, Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Koche, R.P. ORCID: https://orcid.org/0000-0002-6820-5083 and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Nature Genetics 55 (5): 880-890. May 2023

Genomic ALK alterations in primary and relapsed neuroblastoma.
Rosswog, C. ORCID: https://orcid.org/0000-0002-8855-6198, Fassunke, J. ORCID: https://orcid.org/0000-0002-8391-5577, Ernst, A., Schömig-Markiefka, B., Merkelbach-Bruse, S., Bartenhagen, C., Cartolano, M., Ackermann, S. ORCID: https://orcid.org/0000-0002-5869-7344, Theissen, J., Blattner-Johnson, M., Jones, B., Schramm, K., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Nürnberg, P., Ortmann, M., Berthold, F., Peifer, M. ORCID: https://orcid.org/0000-0002-5243-5503, Büttner, R. ORCID: https://orcid.org/0000-0001-8806-4786, Westermann, F., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Simon, T. ORCID: https://orcid.org/0000-0002-3425-8451, Hero, B. and Fischer, M. ORCID: https://orcid.org/0000-0003-1363-1242
British Journal of Cancer 128 (8): 1559-1571. 12 April 2023

Expanding the spectrum of EEF1D neurodevelopmental disorders: biallelic variants in the guanine exchange domain.
Averdunk, L., Al-Thihli, K., Surowy, H., Lüdecke, H.J., Drechsler, M., Yigit, G. ORCID: https://orcid.org/0000-0003-2777-0198, Smorag, L., Hallak, B.A., Li, Y., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Guthoff, T., Wallot, M., Nürnberg, P., Wollnik, B., Abou Jamra, R., Al-Maawali, A. ORCID: https://orcid.org/0000-0002-1404-8887 and Wieczorek, D.
Clinical Genetics 103 (4): 484-491. April 2023

Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita with microcephaly.
Schnabel, F. ORCID: https://orcid.org/0000-0002-9966-8937, Schuler, E., Al-Maawali, A., Chaurasia, A., Syrbe, S., Al-Kindi, A., Bhavani, G.S., Shukla, A., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Nürnberg, P., Banka, S., Girisha, K.M., Li, Y., Wollnik, B. and Yigit, G.
Human Genetics 142 (4): 543-552. April 2023

Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity.
Mangiante, L. ORCID: https://orcid.org/0000-0001-8309-0950, Alcala, N. ORCID: https://orcid.org/0000-0002-5961-5064, Sexton-Oates, A., Di Genova, A. ORCID: https://orcid.org/0000-0002-8582-4660, Gonzalez-Perez, A., Khandekar, A., Bergstrom, E.N., Kim, J. ORCID: https://orcid.org/0000-0002-5210-2004, Liu, X., Blazquez-Encinas, R., Giacobi, C., Le Stang, N., Boyault, S. ORCID: https://orcid.org/0000-0002-2297-6894, Cuenin, C., Tabone-Eglinger, S. ORCID: https://orcid.org/0000-0003-4247-1321, Damiola, F. ORCID: https://orcid.org/0000-0002-0238-1252, Voegele, C., Ardin, M., Michallet, M.C., Soudade, L., Delhomme, T.M. ORCID: https://orcid.org/0000-0003-0265-4246, Poret, A., Brevet, M., Copin, M.C., Giusiano-Courcambeck, S., Damotte, D., Girard, C., Hofman, V., Hofman, P., Mouroux, J., Cohen, C., Lacomme, S., Mazieres, J., de Montpreville, V.T., Perrin, C., Planchard, G., Rousseau, N., Rouquette, I., Sagan, C., Scherpereel, A., Thivolet, F., Vignaud, J.M., Jean, D., Ilg, A.G.S., Olaso, R. ORCID: https://orcid.org/0000-0001-7631-9657, Meyer, V., Boland-Auge, A. ORCID: https://orcid.org/0000-0001-8789-5676, Deleuze, J.F. ORCID: https://orcid.org/0000-0002-5358-4463, Altmuller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Nuernberg, P., Ibáñez-Costa, A. ORCID: https://orcid.org/0000-0003-4649-0095, Castaño, J.P. ORCID: https://orcid.org/0000-0002-3145-7287, Lantuejoul, S., Ghantous, A., Maussion, C. ORCID: https://orcid.org/0000-0003-2266-5276, Courtiol, P., Hernandez-Vargas, H. ORCID: https://orcid.org/0000-0001-6045-2103, Caux, C., Girard, N., Lopez-Bigas, N. ORCID: https://orcid.org/0000-0003-4925-8988, Alexandrov, L.B., Galateau-Salle, F. ORCID: https://orcid.org/0000-0002-2814-1644, Foll, M. ORCID: https://orcid.org/0000-0001-9006-8436 and Fernandez-Cuesta, L. ORCID: https://orcid.org/0000-0002-0724-6703
Nature Genetics 55 (4): 607-618. April 2023

The genomic landscape across 474 surgically accessible epileptogenic human brain lesions.
López-Rivera, J.A., Leu, C., Macnee, M., Khoury, J., Hoffmann, L., Coras, R., Kobow, K., Bhattarai, N., Pérez-Palma, E., Hamer, H., Brandner, S., Rössler, K., Bien, C.G., Kalbhenn, T., Pieper, T., Hartlieb, T., Butler, E., Genovese, G., Becker, K., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Niestroj, L.M., Ferguson, L., Busch, R.M., Nürnberg, P., Najm, I., Blümcke, I. and Lal, D.
Brain 146 (4): 1342-1356. April 2023

Epigenetic regulation of plastin 3 expression by the macrosatellite DXZ4 and the transcriptional regulator CHD4.
Strathmann, E.A., Hölker, I., Tschernoster, N., Hosseinibarkooie, S., Come, J., Martinat, C., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521 and Wirth, B. ORCID: https://orcid.org/0000-0003-4051-5191
American Journal of Human Genetics 110 (3): 442-459. 2 March 2023

Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19.
Mothes, R., Pascual-Reguant, A. ORCID: https://orcid.org/0000-0002-5042-3699, Koehler, R., Liebeskind, J., Liebheit, A. ORCID: https://orcid.org/0009-0007-6743-8313, Bauherr, S. ORCID: https://orcid.org/0000-0002-3736-3361, Philipsen, L. ORCID: https://orcid.org/0000-0001-5112-495X, Dittmayer, C., Laue, M. ORCID: https://orcid.org/0000-0002-6474-9139, von Manitius, R., Elezkurtaj, S., Durek, P., Heinrich, F. ORCID: https://orcid.org/0000-0001-6097-5422, Heinz, G.A. ORCID: https://orcid.org/0000-0002-9330-3689, Guerra, G.M., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Meinhardt, J., Ihlow, J., Radke, J. ORCID: https://orcid.org/0000-0001-9860-2007, Heppner, F.L. ORCID: https://orcid.org/0000-0001-9816-8917, Enghard, P., Stockmann, H. ORCID: https://orcid.org/0000-0002-0934-7620, Aschman, T. ORCID: https://orcid.org/0000-0002-2101-6146, Schneider, J. ORCID: https://orcid.org/0000-0002-0494-1022, Corman, V.M. ORCID: https://orcid.org/0000-0002-3605-0136, Sander, L.E. ORCID: https://orcid.org/0000-0002-0476-9947, Mashreghi, M.F. ORCID: https://orcid.org/0000-0002-8015-6907, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Hocke, A.C. ORCID: https://orcid.org/0000-0002-6935-8612, Niesner, R.A. ORCID: https://orcid.org/0000-0001-8969-5432, Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397 and Hauser, A.E. ORCID: https://orcid.org/0000-0002-7725-9526
Nature Communications 14 (1): 791. 11 February 2023

A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation.
Neuschulz, A. ORCID: https://orcid.org/0000-0001-6163-3344, Bakina, O. ORCID: https://orcid.org/0000-0002-3486-9906, Badillo Lisakowski, V. ORCID: https://orcid.org/0000-0001-5906-2589, Olivares-Chauvet, P., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Gotthardt, M. ORCID: https://orcid.org/0000-0003-1788-3172, Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
Molecular Systems Biology 19 (2): e11147. 10 February 2023

Single-cell clonal tracking of persistent T-cells in allogeneic hematopoietic stem cell transplantation.
Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Keilholz, L., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Frentsch, M., Blau, I.W., Vuong, L., Lesch, S., Movasshagi, K., Tietze-Stolley, C., Loyal, L., Henze, L., Penack, O., Stervbo, U. ORCID: https://orcid.org/0000-0002-2831-8868, Babel, N., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Wittenbecher, F. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Frontiers in Immunology 14 : 1114368. 10 February 2023

Modeling of ACTN4-based podocytopathy using Drosophila nephrocytes.
Odenthal, J., Dittrich, S., Ludwig, V., Merz, T., Reitmeier, K., Reusch, B., Höhne, M., Cosgun, Z.C., Hohenadel, M., Putnik, J., Göbel, H., Rinschen, M.M., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Koehler, S., Schermer, B., Benzing, T., Beck, B.B., Brinkkötter, P.T., Habbig, S. and Bartram, M.P.
Kidney International Reports 8 (2): 317-329. February 2023

Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Keil, P., Wulf, A., Kachariya, N., Reuscher, S., Hühn, K., Silbern, I., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Keller, M., Stehle, R., Zarnack, K. ORCID: https://orcid.org/0000-0003-3527-3378, Sattler, M. ORCID: https://orcid.org/0000-0002-1594-0527, Urlaub, H. ORCID: https://orcid.org/0000-0003-1837-5233 and Sträßer, K. ORCID: https://orcid.org/0000-0003-3533-5516
Nucleic Acids Research 51 (2): 831-851. 25 January 2023

Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and development.
Freitag, K. ORCID: https://orcid.org/0000-0002-5244-3140, Eede, P., Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Sterczyk, N., Schneeberger, S., Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632 and Heppner, F.L. ORCID: https://orcid.org/0000-0001-9816-8917
Communications Biology 6 (1): 40. 13 January 2023

2022

SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution.
Schumann, V.F. ORCID: https://orcid.org/0000-0003-0227-7428, de Castro Cuadrat, R.R. ORCID: https://orcid.org/0000-0001-8289-2599, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Wurmus, R. ORCID: https://orcid.org/0009-0003-0140-4189, Deter, A., Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Dohmen, J. ORCID: https://orcid.org/0000-0002-7826-3025, Faxel, M. ORCID: https://orcid.org/0009-0007-4891-1734, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Blume, A. ORCID: https://orcid.org/0000-0003-3045-8234, Freimuth, J. ORCID: https://orcid.org/0000-0002-9259-3696, Meixner, M., Grau, J.H., Liere, K., Hackenbeck, T., Zietzschmann, F., Gnirss, R., Böckelmann, U., Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Barke, N. ORCID: https://orcid.org/0009-0004-5862-6628, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
Science of the Total Environment 853 : 158931. 20 December 2022

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
Ercu, M., Mücke, M.B. ORCID: https://orcid.org/0000-0002-4957-3307, Pallien, T., Markó, L. ORCID: https://orcid.org/0000-0003-1888-5575, Sholokh, A. ORCID: https://orcid.org/0000-0002-1263-2078, Schächterle, C., Aydin, A. ORCID: https://orcid.org/0000-0002-2890-0225, Kidd, A., Walter, S. ORCID: https://orcid.org/0000-0002-2041-2921, Esmati, Y. ORCID: https://orcid.org/0000-0001-9010-8119, McMurray, B.J. ORCID: https://orcid.org/0000-0003-3394-0667, Lato, D.F. ORCID: https://orcid.org/0000-0002-9263-8532, Sunaga-Franze, D.Y. ORCID: https://orcid.org/0000-0002-6851-9162, Dierks, P.H. ORCID: https://orcid.org/0000-0001-5903-8343, Flores, B.I.M., Walker-Gray, R., Gong, M. ORCID: https://orcid.org/0000-0001-7384-3429, Merticariu, C., Zühlke, K., Russwurm, M., Liu, T., Batolomaeus, T.U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Pautz, S., Schelenz, S., Taube, M., Napieczynska, H. ORCID: https://orcid.org/0000-0001-5091-1185, Heuser, A. ORCID: https://orcid.org/0000-0002-3334-960X, Eichhorst, J., Lehmann, M., Miller, D.C. ORCID: https://orcid.org/0000-0001-9852-677X, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Qadri, F. ORCID: https://orcid.org/0000-0002-8500-489X, Popova, E. ORCID: https://orcid.org/0000-0002-3043-9650, Langanki, R., Movsesian, M.A., Herberg, F.W. ORCID: https://orcid.org/0000-0001-7117-7653, Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Maass, P.G. ORCID: https://orcid.org/0000-0002-2742-8301, Bähring, S. ORCID: https://orcid.org/0000-0001-8734-9755, Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164 and Klussmann, E. ORCID: https://orcid.org/0000-0003-4004-5003
Circulation 146 (23): 1758-1778. 6 December 2022

Detailed stratified GWAS analysis for severe COVID-19 in four European populations.
Degenhardt, F., Ellinghaus, D., Juzenas, S., Lerga-Jaso, J., Wendorff, M., Maya-Miles, D., Uellendahl-Werth, F., ElAbd, H., Rühlemann, M.C., Arora, J., Özer, O., Lenning, O.B., Myhre, R., Vadla, M.S., Wacker, E.M., Wienbrandt, L., Ortiz, A.B., de Salazar, A., Chercoles, A.G., Palom, A., Ruiz, A., Garcia-Fernandez, A.E., Blanco-Grau, A., Mantovani, A., Zanella, A., Holten, A.R., Mayer, A., Bandera, A., Cherubini, A., Protti, A., Aghemo, A., Gerussi, A., Ramirez, A., Braun, A., Nebel, A., Barreira, A., Lleo, A., Teles, A., Kildal, A.B., Biondi, A., Caballero-Garralda, A., Ganna, A., Gori, A., Glück, A., Lind, A., Tanck, A., Hinney, A., Nolla, A.C., Fracanzani, A.L., Peschuck, A., Cavallero, A., Dyrhol-Riise, A.M., Ruello, A., Julià, A., Muscatello, A., Pesenti, A., Voza, A., Rando-Segura, A., Solier, A., Schmidt, A., Cortes, B., Mateos, B., Nafria-Jimenez, B., Schaefer, B., Jensen, B., Bellinghausen, C., Maj, C., Ferrando, C., Horra, C., Quereda, C., Skurk, C., Thibeault, C., Scollo, C., Herr, C., Spinner, C.D., Gassner, C., Lange, C., Hu, C., Paccapelo, C., Lehmann, C., Angelini, C., Cappadona, C., Azuure, C., Bianco, C., Cea, C., Sancho, C., Hoff, D.A.L., Galimberti, D., Prati, D., Haschka, D., Jiménez, D., Pestaña, D., Toapanta, D., Muñiz-Diaz, E., Azzolini, E., Sandoval, E., Binatti, E., Scarpini, E., Helbig, E.T., Casalone, E., Urrechaga, E., Paraboschi, E.M., Pontali, E., Reverter, E., Calderón, E.J., Navas, E., Solligård, E., Contro, E., Arana-Arri, E., Aziz, F., Garcia, F., Sánchez, F.G., Ceriotti, F., Martinelli-Boneschi, F., Peyvandi, F., Kurth, F., Blasi, F., Malvestiti, F., Medrano, F.J., Mesonero, F., Rodriguez-Frias, F., Hanses, F., Müller, F., Hemmrich-Stanisak, G., Bellani, G., Grasselli, G., Pezzoli, G., Costantino, G., Albano, G., Cardamone, G., Bellelli, G., Citerio, G., Foti, G., Lamorte, G., Matullo, G., Baselli, G., Kurihara, H., Neb, H., My, I., Kurth, I., Hernández, I., Pink, I., Rojas, I., Galván-Femenia, I., Holter, J.C., Afset, J.E., Heyckendorf, J., Kässens, J., Damås, J.K., Rybniker, J., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Ampuero, J., Martín, J., Erdmann, J., Banales, J.M., Badia, J.R., Dopazo, J., Schneider, J., Bergan, J., Barretina, J., Walter, J., Quero, J.H., Goikoetxea, J., Delgado, J., Guerrero, J.M., Fazaal, J., Kraft, J., Schröder, J., Risnes, K., Banasik, K., Müller, K.E., Gaede, K.I., Garcia-Etxebarria, K., Tonby, K., Heggelund, L., Izquierdo-Sanchez, L., Bettini, L.Rachele, Sumoy, L., Sander, L.E., Lippert, L.J., Terranova, L., Nkambule, L., Knopp, L., Gustad, L.T., Garbarino, L., Santoro, L., Téllez, L., Roade, L., Ostadreza, M., Intxausti, M., Kogevinas, M., Riveiro-Barciela, M., Berger, M.M., Schaefer, M., Niemi, M.E.K., Gutiérrez-Stampa, M.A., Carrabba, M., Figuera Basso, M.E., Valsecchi, M.G., Hernandez-Tejero, M., Vehreschild, M.J.G.T, Manunta, M., Acosta-Herrera, M., D'Angiò, M., Baldini, M., Cazzaniga, M., Grimsrud, M.M., Cornberg, M., Nöthen, M.M., Marquié, M., Castoldi, M., Cordioli, M., Cecconi, M., D'Amato, M., Augustin, M., Tomasi, M., Boada, M., Dreher, M., Seilmaier, M.J., Joannidis, M., Wittig, M., Mazzocco, M., Ciccarelli, M., Rodríguez-Gandía, M., Bocciolone, M., Miozzo, M., Ayo, N.I., Blay, N., Chueca, N., Montano, N., Braun, N., Ludwig, N., Marx, N., Martínez, N., Cornely, O.A., Witzke, O., Palmieri, O., Faverio, P., Preatoni, P., Bonfanti, P., Omodei, P., Tentorio, P., Castro, P., Rodrigues, P.M., España, P.P., Hoffmann, P., Rosenstiel, P., Schommers, P., Suwalski, P., Pablo, R., Ferrer, R., Bals, R., Gualtierotti, R., Gallego-Durán, R., Nieto, R., Carpani, R., Morilla, R., Badalamenti, S., Haider, S., Ciesek, S., May, S., Bombace, S., Marsal, S., Pigazzini, S., Klein, S., Pelusi, S., Wilfling, S., Bosari, S., Volland, S., Brunak, S., Raychaudhuri, S., Schreiber, S., Heilmann-Heimbach, S., Aliberti, S., Ripke, S., Dudman, S., Wesse, T., Zheng, T., Bahmer, T., Eggermann, T., Illig, T., Brenner, T., Pumarola, T., Feldt, T., Folseraas, T., Cejudo, T.G., Landmesser, U., Protzer, U., Hehr, U., Rimoldi, V., Monzani, V., Skogen, V., Keitel, V., Kopfnagel, V., Friaza, V., Andrade, V., Moreno, V., Albrecht, W., Peter, W., Poller, W., Farre, X., Yi, X., Wang, X., Khodamoradi, Y., Karadeniz, Z., Latiano, A., Goerg, S., Bacher, P., Koehler, P., Tran, F., Zoller, H., Schulte, E.C., Heidecker, B., Ludwig, K.U., Fernández, J., Romero-Gómez, M., Albillos, A., Invernizzi, P., Buti, M., Duga, S., Bujanda, L., Hov, J.R., Lenz, T.L., Asselta, R., Cid, R., Valenti, L., Karlsen, T.H., Cáceres, M. and Franke, A.
Human Molecular Genetics 31 (23): 3945-3966. 1 December 2022

NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition.
Vesting, A.J., Jais, A., Klemm, P., Steuernagel, L., Wienand, P., Fog-Tonnesen, M., Hvid, H., Schumacher, A.L., Kukat, C., Nolte, H., Georgomanolis, T., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Pasparakis, M., Schmidt, A., Krüger, M., Supprian, M.S., Waisman, A., Straub, B.K., Raschzok, N., Bernier, M., Birkenfeld, A.L., Hövelmeyer, N., Brüning, J.C. and Wunderlich, F.T.
Molecular Metabolism 66 : 101626. December 2022

Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies.
Thomalla, D., Beckmann, L., Grimm, C., Oliverio, M., Meder, L., Herling, C.D., Nieper, P., Feldmann, T., Merkel, O., Lorsy, E., da Palma Guerreiro, A., von Jan, J., Kisis, I., Wasserburger, E., Claasen, J., Faitschuk-Meyer, E., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Nürnberg, P., Yang, T.P., Lienhard, M., Herwig, R., Kreuzer, K.A., Pallasch, C.P., Buettner, R., Schäfer, S.C., Hartley, J., Abken, H., Peifer, M., Kashkar, H., Knittel, G., Eichhorst, B., Ullrich, R.T., Herling, M., Reinhardt, H.C., Hallek, M., Schweiger, M.R. and Frenzel, L.P.
Blood 140 (20): 2113-2126. 17 November 2022

Somatic mosaicism in STAG2-associated cohesinopathies: Expansion of the genotypic and phenotypic spectrum.
Schmidt, J., Dreha-Kulaczewski, S., Zafeiriou, M.P., Schreiber, M.K., Wilken, B., Funke, R., Neuhofer, C.M., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Thiele, H., Nürnberg, P., Biskup, S., Li, Y., Zimmermann, W.H., Kaulfuß, S., Yigit, G. and Wollnik, B.
Frontiers in Cell and Developmental Biology 10 : 1025332. 16 November 2022

Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.
Houwaart, Torsten, Belhaj, S., Tawalbeh, E., Nagels, D., Fröhlich, Y., Finzer, P., Ciruela, P., Sabrià, A., Herrero, M., Andrés, C., Antón, A., Benmoumene, A., Asskali, D., Haidar, H., von Dahlen, J., Nicolai, J., Stiller, M., Blum, J., Lange, C., Adelmann, C., Schroer, B., Osmers, U., Grice, C., Kirfel, P.P., Jomaa, H., Strelow, D., Hülse, L., Pigulla, M., Kreuzer, P., Tyshaieva, A., Weber, J., Wienemann, T., Kohns Vasconcelos, M., Hoffmann, K., Lübke, N., Hauka, S., Andree, M., Scholz, C.J., Jazmati, N., Göbels, K., Zotz, R., Pfeffer, K., Timm, J., Ehlkes, L., Walker, A. and Dilthey, A.T.
Eurosurveillance 27 (43): 2101089. 27 October 2022

A novel MAP3K20 mutation causing centronuclear myopathy-6 with fiber-type disproportion in a Pakistani family.
Ahmad, I. ORCID: https://orcid.org/0000-0003-4845-9227, Khan, A., Noor Ul Ayan, H., Budde, B., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Korejo, A.A., Nürnberg, G., Thiele, H., Tariq, M. ORCID: https://orcid.org/0000-0002-5334-403X, Nürnberg, P. and Erdmann, J.
Journal of Human Genetics 11 October 2022

Candesartan does not activate PPAR(γ) and its target genes in early gestation trophoblasts.
Neuper, L., Kummer, D., Forstner, D. ORCID: https://orcid.org/0000-0001-5451-7580, Guettler, J. ORCID: https://orcid.org/0000-0002-8141-5712, Ghaffari-Tabrizi-Wizsy, N., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Juch, H., Nonn, O. ORCID: https://orcid.org/0000-0001-6385-2866 and Gauster, M. ORCID: https://orcid.org/0000-0003-0386-6857
International Journal of Molecular Sciences 23 (20): 12326. October 2022

WARS1 and SARS1: two tRNA synthetases implicated in autosomal recessive microcephaly.
Bögershausen, N., Krawczyk, H.E., Jamra, R.A., Lin, S.J. ORCID: https://orcid.org/0000-0002-7559-6529, Yigit, G., Hüning, I., Polo, A.M., Vona, B. ORCID: https://orcid.org/0000-0002-6719-3447, Huang, K., Schmidt, J., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Luppe, J., Platzer, K., Dörgeloh, B.B., Busche, A., Biskup, S., Mendes, M.I., Smith, D.E.C., Salomons, G.S., Zibat, A., Bültmann, E., Nürnberg, P., Spielmann, M., Lemke, J.R., Li, Y., Zenker, M. ORCID: https://orcid.org/0000-0003-1618-9269, Varshney, G.K., Hillen, H.S., Kratz, C.P. and Wollnik, B.
Human Mutation 43 (10): 1454-1471. October 2022

Reliable assessment of telomere maintenance mechanisms in neuroblastoma.
Meeser, A., Bartenhagen, C., Werr, L., Hellmann, A.M., Kahlert, Y., Hemstedt, N., Nürnberg, P., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Ackermann, S., Hero, B., Simon, T., Peifer, M., Fischer, M. and Rosswog, C. ORCID: https://orcid.org/0000-0002-8855-6198
Cell and Bioscience 12 (1): 160. 24 September 2022

Alport syndrome and autosomal dominant tubulointerstitial kidney disease frequently underlie end stage renal disease of unknown origin - a single center analysis.
Leenen, E., Erger, F., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Wenzel, A., Thiele, H., Harth, A., Tschernoster, N., Lokhande, S., Joerres, A., Becker, J.U., Ekici, A., Huettel, B., Beck, B. and Weidemann, A.
Nephrology Dialysis Transplantation 37 (10): 1895-1905. 22 September 2022

Mutations in TAF8 cause a neurodegenerative disorder.
Wong, K.M. ORCID: https://orcid.org/0000-0002-5449-6318, Jepsen, W.M., Efthymiou, S., Salpietro, V., Sanchez-Castillo, M., Yip, J., Kriouile, Y., Diegmann, S. ORCID: https://orcid.org/0000-0001-9134-6303, Dreha-Kulaczewski, S., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Thiele, H., Nürnberg, P. ORCID: https://orcid.org/0000-0002-7228-428X, Toosi, M.B., Akhondian, J., Ghayoor Karimiani, E., Hummel-Abmeier, H., Huppke, B., Houlden, H. ORCID: https://orcid.org/0000-0002-2866-7777, Gärtner, J., Maroofian, R. and Huppke, P.
Brain 145 (9): 3022-3034. September 2022

Single cell‐ and spatial 'omics revolutionize physiology.
Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295 and Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521
Acta Physiologica 235 (4): e13848. August 2022

Full-length spatial transcriptomics reveals the unexplored isoform diversity of the myocardium post-MI.
Boileau, E., Li, X., Naarmann-de Vries, I.S., Becker, C., Casper, R., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Leuschner, F. and Dieterich, C. ORCID: https://orcid.org/0000-0001-9468-6311
Frontiers in Genetics 13 : 912572. 22 July 2022

De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway.
Asif, M., Kaygusuz, E., Shinawi, M., Nickelsen, A., Hsieh, T.C., Wagle, P., Budde, B., Hochscherf, J., Abdullah, U., Höning, S., Nienberg, C., Lindenblatt, D., Noegel, A.A., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Thiele, H., Motameny, S., Fleischer, N., Segal, I., Pais, L., Tinschert, S., Samra, N.G., Savatt, J.M., Rudy, N.L., De Luca, C., Fortugno, P., White, S.M., Krawitz, P., Hurst, A.C.E., Niefind, K., Jose, J., Brancati, F., Nürnberg, P. and Hussain, M.S.
Human Genetics and Genomics Advances 3 (3): 100111. 14 July 2022

Uncovering the contribution of moderate-penetrance susceptibility genes to breast cancer by whole-exome sequencing and targeted enrichment sequencing of candidate genes in women of European ancestry.
Dumont, M. ORCID: https://orcid.org/0000-0002-5488-4839, Weber-Lassalle, N., Joly-Beauparlant, C., Ernst, C. ORCID: https://orcid.org/0000-0001-7756-8815, Droit, A., Feng, B.J., Dubois, S., Collin-Deschesnes, A.C., Soucy, P., Vallée, M., Fournier, F., Lemaçon, A. ORCID: https://orcid.org/0000-0002-1817-7029, Adank, M.A., Allen, J. ORCID: https://orcid.org/0000-0002-8677-2225, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Arnold, N., Ausems, M.G.E.M. ORCID: https://orcid.org/0000-0003-0305-3477, Berutti, R., Bolla, M.K., Bull, S. ORCID: https://orcid.org/0000-0002-3280-7154, Carvalho, S., Cornelissen, S., Dufault, M.R., Dunning, A.M., Engel, C. ORCID: https://orcid.org/0000-0002-7247-282X, Gehrig, A., Geurts-Giele, W.R.R., Gieger, C., Green, J. ORCID: https://orcid.org/0000-0002-7005-2928, Hackmann, K., Helmy, M., Hentschel, J., Hogervorst, F.B.L., Hollestelle, A. ORCID: https://orcid.org/0000-0003-1166-1966, Hooning, M.J., Horváth, J., Ikram, M.A., Kaulfuß, S. ORCID: https://orcid.org/0000-0003-2577-9711, Keeman, R., Kuang, D. ORCID: https://orcid.org/0000-0003-3554-0464, Luccarini, C., Maier, W., Martens, J.W.M. ORCID: https://orcid.org/0000-0002-3428-3366, Niederacher, D., Nürnberg, P. ORCID: https://orcid.org/0000-0002-7228-428X, Ott, C.E. ORCID: https://orcid.org/0000-0003-3627-3791, Peters, A. ORCID: https://orcid.org/0000-0001-6645-0985, Pharoah, P.D.P., Ramirez, A. ORCID: https://orcid.org/0000-0003-4991-763X, Ramser, J., Riedel-Heller, S., Schmidt, G., Shah, M., Scherer, M., Stäbler, A., Strom, T.M., Sutter, C., Thiele, H., van Asperen, C.J., van der Kolk, L., van der Luijt, R.B., Volk, A.E., Wagner, M. ORCID: https://orcid.org/0000-0003-2589-6440, Waisfisz, Q., Wang, Q., Wang-Gohrke, S., Weber, B.H.F. ORCID: https://orcid.org/0000-0002-8808-7723, Devilee, P. ORCID: https://orcid.org/0000-0002-8023-2009, Tavtigian, S., Bader, G.D. ORCID: https://orcid.org/0000-0003-0185-8861, Meindl, A., Goldgar, D.E., Andrulis, I.L. ORCID: https://orcid.org/0000-0002-4226-6435, Schmutzler, R.K., Easton, D.F., Schmidt, M.K. ORCID: https://orcid.org/0000-0002-2228-429X, Hahnen, E. and Simard, J. ORCID: https://orcid.org/0000-0001-6906-3390
Cancers 14 (14): 3363. 11 July 2022

Prevalence of cancer predisposition germline variants in male breast cancer patients: results of the German Consortium for Hereditary Breast and Ovarian Cancer.
Rolfes, M., Borde, J., Möllenhoff, K. ORCID: https://orcid.org/0000-0001-7861-3892, Kayali, M., Ernst, C. ORCID: https://orcid.org/0000-0001-7756-8815, Gehrig, A., Sutter, C. ORCID: https://orcid.org/0000-0003-4051-5888, Ramser, J., Niederacher, D., Horváth, J., Arnold, N., Meindl, A., Auber, B., Rump, A., Wang-Gohrke, S., Ritter, J., Hentschel, J., Thiele, H., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Nürnberg, P. ORCID: https://orcid.org/0000-0002-7228-428X, Rhiem, K., Engel, C., Wappenschmidt, B., Schmutzler, R.K., Hahnen, E. and Hauke, J.
Cancers 14 (13): 3292. 5 July 2022

Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model.
Freitag, K. ORCID: https://orcid.org/0000-0002-5244-3140, Sterczyk, N., Wendlinger, S. ORCID: https://orcid.org/0000-0001-6771-4794, Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Schulz, J., Farztdinov, V., Mülleder, M., Ralser, M., Houtman, J., Fleck, L., Braeuning, C. ORCID: https://orcid.org/0009-0007-1439-9920, Sansevrino, R., Hoffmann, C., Milovanovic, D., Sigrist, S.J., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Heppner, F.L. and Jendrach, M.
Journal of Neuroinflammation 19 (1): 172. 2 July 2022

De novo whole genome assembly of the Roborovski dwarf hamster (Phodopus roborovskii) genome, an animal model for severe/critical COVID-19.
Andreotti, S. ORCID: https://orcid.org/0000-0001-7678-9720, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Nouailles, G., Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Bieniara, M., Trimpert, J. and Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806
Genome Biology and Evolution 14 (7): evac100. July 2022

Male carriers of HLA-C*04:01 have increased risk of cardiac injury in COVID-19.
Suwalski, P. ORCID: https://orcid.org/0000-0002-2678-2595, Violano, M., Müller, M., Patriki, D., Thibeault, C. ORCID: https://orcid.org/0000-0002-8979-9386, Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Wang, X., Karadeniz, Z., Saccomanno, J., Doehn, J.M., Hübner, R.H. ORCID: https://orcid.org/0000-0001-5969-2089, Hinzmann, B. ORCID: https://orcid.org/0000-0003-0229-3081, Beer, H.J., Wiggli, B., Siemann, S., Suttorp, N. ORCID: https://orcid.org/0000-0002-3958-1151, Witzenrath, M. ORCID: https://orcid.org/0000-0002-9787-5633, Hippenstiel, S. ORCID: https://orcid.org/0000-0002-5146-1064, Skurk, C. ORCID: https://orcid.org/0000-0003-4953-601X, Poller, W. ORCID: https://orcid.org/0000-0002-2805-6634, Sander, L.E. ORCID: https://orcid.org/0000-0002-0476-9947, Kurth, F. ORCID: https://orcid.org/0000-0002-3807-473X, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Guettouche, T., Landmesser, U. ORCID: https://orcid.org/0000-0002-0214-3203 and Heidecker, B. ORCID: https://orcid.org/0000-0002-3811-7920
Journal of Cardiovascular Aging 2 (3): 33. 27 June 2022