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Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T. and Meyer, K. and Roske, Y. and Uyar, B. and Akalin, A. and Imami, K. and Ishihama, Y. and Daumke, O. and Selbach, M.
Nature Communications 15 (1): 3146. 11 April 2024

Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Dörner, P.J. and Anandakumar, H. and Röwekamp, I. and Fiocca Vernengo, F. and Millet Pascual-Leone, B. and Krzanowski, M. and Sellmaier, J. and Brüning, U. and Fritsche-Guenther, R. and Pfannkuch, L. and Kurth, F. and Milek, M. and Igbokwe, V. and Löber, U. and Gutbier, B. and Holstein, M. and Heinz, G.A. and Mashreghi, M.F. and Schulte, L.N. and Klatt, A.B. and Caesar, S. and Wienhold, S.M. and Offermanns, S. and Mack, M. and Witzenrath, M. and Jordan, S. and Beule, D. and Kirwan, J.A. and Forslund, S.K. and Wilck, N. and Bartolomaeus, H. and Heimesaat, M.M. and Opitz, B.
Nature Communications 15 (1): 2788. 30 March 2024

Ion mobility-tandem mass spectrometry of mucin-type O-glycans.
Bechtella, L. and Chunsheng, J. and Fentker, K. and Ertürk, G.R. and Safferthal, M. and Polewski, Ł. and Götze, M. and Graeber, S.Y. and Vos, G.M. and Struwe, W.B. and Mall, M.A. and Mertins, P. and Karlsson, N.G. and Pagel, K.
Nature Communications 15 (1): 2611. 23 March 2024

Heterozygous missense variant in GLI2 impairs human endocrine pancreas development.
Mueller, L.M. and Isaacson, A. and Wilson, H. and Salowka, A. and Tay, I. and Gong, M. and Samir Elbarbary, N. and Raile, K. and Spagnoli, F.M.
Nature Communications 15 (1): 2483. 20 March 2024

Canonical and non-canonical integrin-based adhesions dynamically interconvert.
Lukas, F. and Matthaeus, C. and López-Hernández, T. and Lahmann, I. and Schultz, N. and Lehmann, M. and Puchkov, D. and Pielage, J. and Haucke, V. and Maritzen, T.
Nature Communications 15 (1): 2093. 7 March 2024

Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Flügel, T. and Schacherl, M. and Unbehaun, A. and Schroeer, B. and Dabrowski, M. and Bürger, J. and Mielke, T. and Sprink, T. and Diebolder, C.A. and Guillén Schlippe, Y.V. and Spahn, C.M.T.
Nature Communications 15 (1): 1756. 26 February 2024

MarShie: a clearing protocol for 3D analysis of single cells throughout the bone marrow at subcellular resolution.
Mertens, T.F. and Liebheit, A.T. and Ehl, J. and Köhler, R. and Rakhymzhan, A. and Woehler, A. and Katthän, L. and Ebel, G. and Liublin, W. and Kasapi, A. and Triantafyllopoulou, A. and Schulz, T.J. and Niesner, R.A. and Hauser, A.E.
Nature Communications 15 (1): 1764. 26 February 2024

Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment.
Juul-Madsen, K. and Parbo, P. and Ismail, R. and Ovesen, P.L. and Schmidt, V. and Madsen, L.S. and Thyrsted, J. and Gierl, S. and Breum, M. and Larsen, A. and Andersen, M.N. and Romero-Ramos, M. and Holm, C.K. and Andersen, G.R. and Zhao, H. and Schuck, P. and Nygaard, J.V. and Sutherland, D.S. and Eskildsen, S.F. and Willnow, T.E. and Brooks, D.J. and Vorup-Jensen, T.
Nature Communications 15 (1): 1224. 9 February 2024

Sensory Schwann cells set perceptual thresholds for touch and selectively regulate mechanical nociception.
Ojeda-Alonso, J. and Calvo-Enrique, L. and Paricio-Montesinos, R. and Kumar, R. and Zhang, M.D. and Poulet, J.F.A. and Ernfors, P. and Lewin, G.R.
Nature Communications 15 (1): 898. 6 February 2024

Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes.
Company, C. and Schmitt, M.J. and Dramaretska, Y. and Serresi, M. and Kertalli, S. and Jiang, B. and Yin, J.A. and Aguzzi, A. and Barozzi, I. and Gargiulo, G.
Nature Communications 15 (1): 897. 5 February 2024

Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis.
Drexhage, L.Z. and Zhang, S. and Dupont, M. and Ragaller, F. and Sjule, E. and Cabezas-Caballero, J. and Deimel, L.P. and Robertson, H. and Russell, R.A. and Dushek, O. and Sezgin, E. and Karaji, N. and Sattentau, Q.J.
Nature Communications 15 (1): 541. 15 January 2024

Epstein-Barr virus-driven B cell lymphoma mediated by a direct LMP1-TRAF6 complex.
Giehler, F. and Ostertag, M.S. and Sommermann, T. and Weidl, D. and Sterz, K.R. and Kutz, H. and Moosmann, A. and Feller, S.M. and Geerlof, A. and Biesinger, B. and Popowicz, G.M. and Kirchmair, J. and Kieser, A.
Nature Communications 15 (1): 414. 10 January 2024

Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells.
Urzi, A. and Lahmann, I. and Nguyen, L.V.N. and Rost, B.R. and García-Pérez, A. and Lelievre, N. and Merritt-Garza, M.E. and Phan, H.C and Bassell, G.J. and Rossoll, W. and Diecke, S. and Kunz, S. and Schmitz, D. and Gouti, M.
Nature Communications 14 (1): 8043. 19 December 2023

Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery.
Wang, Z. and Shaabani, S. and Gao, X. and Ng, Y.L.D. and Sapozhnikova, V. and Mertins, P. and Krönke, J. and Dömling, A.
Nature Communications 14 (1): 8437. 19 December 2023

RIF1 regulates early replication timing in murine B cells.
Malzl, D. and Peycheva, M. and Rahjouei, A. and Gnan, S. and Klein, K.N. and Nazarova, M. and Schoeberl, U.E. and Gilbert, D.M. and Buonomo, S.C.B. and Di Virgilio, M. and Neumann, T. and Pavri, R.
Nature Communications 14 (1): 8049. 11 December 2023

Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis.
Dönig, J. and Mende, H. and Davila Gallesio, J. and Wagner, K. and Hotz, P. and Schunck, K. and Piller, T. and Hölper, S. and Uhan, S. and Kaulich, M. and Wirth, M. and Keller, U. and Tascher, G. and Bohnsack, K.E. and Müller, S.
Nature Communications 14 (1): 8121. 8 December 2023

The SPOC proteins DIDO3 and PHF3 co-regulate gene expression and neuronal differentiation.
Benedum, J. and Franke, V. and Appel, L.M. and Walch, L. and Bruno, M. and Schneeweiss, R. and Gruber, J. and Oberndorfer, H. and Frank, E. and Strobl, X. and Polyansky, A. and Zagrovic, B. and Akalin, A. and Slade, D.
Nature Communications 14 (1): 7912. 30 November 2023

Associations of myeloid cells with cellular and humoral responses following vaccinations in patients with neuroimmunological diseases.
Wang, M. and Dehlinger, A. and Fernández Zapata, C. and Golan, M. and Gallaccio, G. and Sander, L.E. and Schlickeiser, S. and Kunkel, D. and Schmitz-Hübsch, T. and Sawitzki, B. and Karni, A. and Braun, J. and Loyal, L. and Thiel, A. and Bellmann-Strobl, J. and Paul, F. and Meyer-Arndt, L. and Boettcher, C.
Nature Communications 14 (1): 7728. 25 November 2023

Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner, N. and Cauchy, P. and Franke, V. and Giefing, M. and Fornes, O. and Vankadari, N. and Assi, S.A. and Costanza, M. and Weniger, M.A. and Akalin, A. and Anagnostopoulos, I. and Bukur, T. and Casarotto, M.G. and Damm, F. and Daumke, O. and Edginton-White, B. and Gebhardt, J.C.M. and Grau, M. and Grunwald, S. and Hansmann, M.L. and Hartmann, S. and Huber, L. and Kärgel, E. and Lusatis, S. and Noerenberg, D. and Obier, N. and Pannicke, U. and Fischer, A. and Reisser, A. and Rosenwald, A. and Schwarz, K. and Sundararaj, S. and Weilemann, A. and Winkler, W. and Xu, W. and Lenz, G. and Rajewsky, K. and Wasserman, W.W. and Cockerill, P.N. and Scheidereit, C. and Siebert, R. and Küppers, R. and Grosschedl, R. and Janz, M. and Bonifer, C. and Mathas, S.
Nature Communications 14 (1): 6947. 7 November 2023

Streamlined structure determination by cryo-electron tomography and subtomogram averaging using TomoBEAR.
Balyschew, N. and Yushkevich, A. and Mikirtumov, V. and Sanchez, R.M. and Sprink, T. and Kudryashev, M.
Nature Communications 14 (1): 6543. 17 October 2023

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Budu-Aggrey, A. and Kilanowski, A. and Sobczyk, M.K. and Shringarpure, S.S. and Mitchell, R. and Reis, K. and Reigo, A. and Mägi, R. and Nelis, M. and Tanaka, N. and Brumpton, B.M. and Thomas, L.F. and Sole-Navais, P. and Flatley, C. and Espuela-Ortiz, A. and Herrera-Luis, E. and Lominchar, J.V.T. and Bork-Jensen, J. and Marenholz, I. and Arnau-Soler, A. and Jeong, A. and Fawcett, K.A. and Baurecht, H. and Rodriguez, E. and Alves, A.C. and Kumar, A. and Sleiman, P.M. and Chang, X. and Medina-Gomez, C. and Hu, C. and Xu, C.J. and Qi, C. and El-Heis, S. and Titcombe, P. and Antoun, E. and Fadista, J. and Wang, C.A. and Thiering, E. and Wu, B. and Kress, S. and Kothalawala, D.M. and Kadalayil, L. and Duan, J. and Zhang, H. and Hadebe, S. and Hoffmann, T. and Jorgenson, E. and Choquet, H. and Risch, N. and Njølstad, P. and Andreassen, O.A. and Johansson, S. and Almqvist, C. and Gong, T. and Ullemar, V. and Karlsson, R. and Magnusson, P.K.E. and Szwajda, A. and Burchard, E.G. and Thyssen, J.P. and Hansen, T. and Kårhus, L.L. and Dantoft, T.M. and Jeanrenaud, A.C.S.N. and Ghauri, A. and Arnold, A. and Homuth, G. and Lau, S. and Nöthen, M.M. and Hübner, N. and Imboden, M. and Visconti, A. and Falchi, M. and Bataille, V. and Hysi, P. and Ballardini, N. and Boomsma, D.I. and Hottenga, J.J. and Müller-Nurasyid, M. and Ahluwalia, T.S. and Stokholm, J. and Chawes, B. and Schoos, A.M.M. and Esplugues, A. and Bustamante, M. and Raby, B. and Arshad, S. and German, C. and Esko, T. and Milani, L.A. and Metspalu, A. and Terao, C. and Abuabara, K. and Løset, M. and Hveem, K. and Jacobsson, B. and Pino-Yanes, M. and Strachan, D.P. and Grarup, N. and Linneberg, A. and Lee, Y. and Probst-Hensch, N. and Weidinger, S. and Jarvelin, M.R. and Melén, E. and Hakonarson, H. and Irvine, A.D. and Jarvis, D. and Nijsten, T. and Duijts, L. and Vonk, J.M. and Koppelmann, G.H. and Godfrey, K.M. and Barton, S.J. and Feenstra, B. and Pennell, C.E. and Sly, P.D. and Holt, P.G. and Williams, L.K. and Bisgaard, H. and Bønnelykke, K. and Curtin, J. and Simpson, A. and Murray, C. and Schikowski, T. and Bunyavanich, S. and Weiss, S.T. and Holloway, J.W. and Min, J.L. and Brown, S.J. and Standl, M. and Paternoster, L.
Nature Communications 14 (1): 6172. 4 October 2023

Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide.
Andrikopoulos, P. and Aron-Wisnewsky, J. and Chakaroun, R. and Myridakis, A. and Forslund, S.K. and Nielsen, T. and Adriouch, S. and Holmes, B. and Chilloux, J. and Vieira-Silva, S. and Falony, G. and Salem, J.E. and Andreelli, F. and Belda, E. and Kieswich, J. and Chechi, K. and Puig-Castellvi, F. and Chevalier, M. and Le Chatelier, E. and Olanipekun, M.T. and Hoyles, L. and Alves, R. and Helft, G. and Isnard, R. and Køber, L. and Coelho, L.P. and Rouault, C. and Gauguier, D. and Gøtze, J.P. and Prifti, E. and Froguel, P. and Zucker, J.D. and Bäckhed, F. and Vestergaard, H. and Hansen, T. and Oppert, J.M. and Blüher, M. and Nielsen, J. and Raes, J. and Bork, P. and Yaqoob, M.M. and Stumvoll, M. and Pedersen, O. and Ehrlich, S.D. and Clément, K. and Dumas, M.E.
Nature Communications 14 (1): 5843. 20 September 2023

Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice.
Monsorno, K. and Ginggen, K. and Ivanov, A. and Buckinx, A. and Lalive, A.L. and Tchenio, A. and Benson, S. and Vendrell, M. and D'Alessandro, A. and Beule, D. and Pellerin, L. and Mameli, M. and Paolicelli, R.C.
Nature Communications 14 (1): 5749. 16 September 2023

The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis.
Schoeler, M. and Ellero-Simatos, S. and Birkner, T. and Mayneris-Perxachs, J. and Olsson, L. and Brolin, H. and Löber, U. and Kraft, J.D. and Polizzi, A. and Martí-Navas, M. and Puig, J. and Moschetta, A. and Montagner, A. and Gourdy, P. and Heymes, C. and Guillou, H. and Tremaroli, V. and Fernández-Real, J.M. and Forslund, S.K. and Burcelin, R. and Caesar, R.
Nature Communications 14 (1): 5329. 1 September 2023

Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence.
Lluch, A. and Latorre, J. and Serena-Maione, A. and Espadas, I. and Caballano-Infantes, E. and Moreno-Navarrete, J.M. and Oliveras-Cañellas, N. and Ricart, W. and Malagón, M.M. and Martin-Montalvo, A. and Birchmeier, W. and Szymanski, W. and Graumann, J. and Gómez-Serrano, M. and Sommariva, E. and Fernández-Real, J.M. and Ortega, F.J.
Nature Communications 14 (1): 5106. 22 August 2023

Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level.
John, L. and Poos, A.M. and Brobeil, A. and Schinke, C. and Huhn, S. and Prokoph, N. and Lutz, R. and Wagner, B. and Zangari, M. and Tirier, S.M. and Mallm, J.P. and Schumacher, S. and Vonficht, D. and Solé-Boldo, L. and Quick, S. and Steiger, S. and Przybilla, M.J. and Bauer, K. and Baumann, A. and Hemmer, S. and Rehnitz, C. and Lückerath, C. and Sachpekidis, C. and Mechtersheimer, G. and Haberkorn, U. and Dimitrakopoulou-Strauss, A. and Reichert, P. and Barlogie, B. and Müller-Tidow, C. and Goldschmidt, H. and Hillengass, J. and Rasche, L. and Haas, S.F. and van Rhee, F. and Rippe, K. and Raab, M.S. and Sauer, S. and Weinhold, N.
Nature Communications 14 (1): 5011. 17 August 2023

Robust phenotyping of highly multiplexed tissue imaging data using pixel-level clustering.
Liu, C.C. and Greenwald, N.F. and Kong, A. and McCaffrey, E.F. and Leow, K.X. and Mrdjen, D. and Cannon, B.J. and Rumberger, J.L. and Varra, S.R. and Angelo, M.
Nature Communications 14 (1): 4618. 1 August 2023

Mislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3.
Kornienko, J. and Rodríguez-Martínez, M. and Fenzl, K. and Hinze, F. and Schraivogel, D. and Grosch, M. and Tunaj, B. and Lindenhofer, D. and Schraft, L. and Kueblbeck, M. and Smith, E. and Mao, C. and Brown, E. and Owens, A. and Saguner, A.M. and Meder, B. and Parikh, V. and Gotthardt, M. and Steinmetz, L.M.
Nature Communications 14 (1): 4312. 18 July 2023

Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction.
Yeh, Y.T. and Sona, C. and Yan, X. and Li, Y. and Pathak, A. and McDermott, M.I. and Xie, Z. and Liu, L. and Arunagiri, A. and Wang, Y. and Cazenave-Gassiot, A. and Ghosh, A. and von Meyenn, F. and Kumarasamy, S. and Najjar, S.M. and Jia, S. and Wenk, M.R. and Traynor-Kaplan, A. and Arvan, P. and Barg, S. and Bankaitis, V.A. and Poy, M.N.
Nature Communications 14 (1): 4250. 17 July 2023

Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.
Fuchs, S. and Danßmann, C. and Klironomos, F. and Winkler, A. and Fallmann, J. and Kruetzfeldt, L.M. and Szymansky, A. and Naderi, J. and Bernhart, S.H. and Grunewald, L. and Helmsauer, K. and Rodriguez-Fos, E. and Kirchner, M. and Mertins, P. and Astrahantseff, K. and Suenkel, C. and Toedling, J. and Meggetto, F. and Remke, M. and Stadler, P.F. and Hundsdoerfer, P. and Deubzer, H.E. and Künkele, A. and Lang, P. and Fuchs, J. and Henssen, A.G. and Eggert, A. and Rajewsky, N. and Hertwig, F. and Schulte, J.H.
Nature Communications 14 (1): 3936. 4 July 2023

Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy.
Grosch, M. and Schraft, L. and Chan, A. and Küchenhoff, L. and Rapti, K. and Ferreira, A.M. and Kornienko, J. and Li, S. and Radke, M.H. and Krämer, C. and Clauder-Münster, S. and Perlas, E. and Backs, J. and Gotthardt, M. and Dieterich, C. and van den Hoogenhof, M.M.G. and Grimm, D. and Steinmetz, L.M.
Nature Communications 14 (1): 3714. 22 June 2023

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.
Lin, M. and Hartl, K. and Heuberger, J. and Beccaceci, G. and Berger, H. and Li, H. and Liu, L. and Müllerke, S. and Conrad, T. and Heymann, F. and Woehler, A. and Tacke, F. and Rajewsky, N. and Sigal, M.
Nature Communications 14 (1): 3025. 25 May 2023

Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2.
Li, R. and Shao, J. and Jin, Y.J. and Kawase, H. and Ong, Y.T. and Troidl, K. and Quan, Q. and Wang, L. and Bonnavion, R. and Wietelmann, A. and Helmbacher, F. and Potente, M. and Graumann, J. and Wettschureck, N. and Offermanns, S.
Nature Communications 14 (1): 1980. 8 April 2023

Role of TMEM100 in mechanically insensitive nociceptor un-silencing.
Nees, T.A. and Wang, N. and Adamek, P. and Zeitzschel, N. and Verkest, C. and La Porta, C. and Schaefer, I. and Virnich, J. and Balkaya, S. and Prato, V. and Morelli, C. and Begay, V. and Lee, Y.J. and Tappe-Theodor, A. and Lewin, G.R. and Heppenstall, P.A. and Taberner, F.J. and Lechner, S.G.
Nature Communications 14 (1): 1899. 5 April 2023

The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
Meier, M. and Gupta, M. and Akgül, S. and McDougall, M. and Imhof, T. and Nikodemus, D. and Reuten, R. and Moya-Torres, A. and To, V. and Ferens, F. and Heide, F. and Padilla-Meier, G.P. and Kukura, P. and Huang, W. and Gerisch, B. and Mörgelin, M. and Poole, K. and Antebi, A. and Koch, M. and Stetefeld, J.
Nature Communications 14 (1): 1226. 3 March 2023

Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation.
Li, B. and Zeis, P. and Zhang, Y. and Alekseenko, A. and Fürst, E. and Sanchez, Y.P. and Lin, G. and Tekkedil, M.M. and Piazza, I. and Steinmetz, L.M. and Pelechano, V.
Nature Communications 14 (1): 910. 17 February 2023

Cryo-EM captures early ribosome assembly in action.
Qin, B. and Lauer, S.M. and Balke, A. and Vieira-Vieira, C.H. and Bürger, J. and Mielke, T. and Selbach, M. and Scheerer, P. and Spahn, C.M.T. and Nikolay, R.
Nature Communications 14 (1): 898. 17 February 2023

Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19.
Mothes, R. and Pascual-Reguant, A. and Koehler, R. and Liebeskind, J. and Liebheit, A. and Bauherr, S. and Philipsen, L. and Dittmayer, C. and Laue, M. and von Manitius, R. and Elezkurtaj, S. and Durek, P. and Heinrich, F. and Heinz, G.A. and Guerra, G.M. and Obermayer, B. and Meinhardt, J. and Ihlow, J. and Radke, J. and Heppner, F.L. and Enghard, P. and Stockmann, H. and Aschman, T. and Schneider, J. and Corman, V.M. and Sander, L.E. and Mashreghi, M.F. and Conrad, T. and Hocke, A.C. and Niesner, R.A. and Radbruch, H. and Hauser, A.E.
Nature Communications 14 (1): 791. 11 February 2023

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Appel, L.M. and Franke, V. and Benedum, J. and Grishkovskaya, I. and Strobl, X. and Polyansky, A. and Ammann, G. and Platzer, S. and Neudolt, A. and Wunder, A. and Walch, L. and Kaiser, S. and Zagrovic, B. and Djinovic-Carugo, K. and Akalin, A. and Slade, D.
Nature Communications 14 (1): 166. 11 January 2023

Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.
Leng, H. and Zhang, H. and Li, L. and Zhang, S. and Wang, Y. and Chavda, S.J. and Galas-Filipowicz, D. and Lou, H. and Ersek, A. and Morris, E.V. and Sezgin, E. and Lee, Y.H. and Li, Y. and Lechuga-Vieco, A.V. and Tian, M. and Mi, J.Q. and Yong, K. and Zhong, Q. and Edwards, C.M. and Simon, A.K. and Horwood, N.J.
Nature Communications 13 (1): 7868. 22 December 2022

Calcium-permeable channelrhodopsins for the photocontrol of calcium signalling.
Fernandez Lahore, R.G. and Pampaloni, N.P. and Peter, E. and Heim, M.M. and Tillert, L. and Vierock, J. and Oppermann, J. and Walther, J. and Schmitz, D. and Owald, D. and Plested, A.J.R. and Rost, B.R. and Hegemann, P.
Nature Communications 13 (1): 7844. 21 December 2022

Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.
Melo, A.A. and Sprink, T. and Noel, J.K. and Vázquez-Sarandeses, E. and van Hoorn, C. and Mohd, S. and Loerke, J. and Spahn, C.M.T. and Daumke, O.
Nature Communications 13 (1): 7641. 10 December 2022

Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease.
Widjaja, A.A. and Viswanathan, S. and Shekeran, S.G. and Adami, E. and Lim, W.W. and Chothani, S. and Tan, J. and Goh, J.W.T. and Chen, H.M. and Lim, S.Y. and Boustany-Kari, C.M. and Hawkins, J. and Petretto, E. and Hübner, N. and Schafer, S. and Coffman, T.M. and Cook, S.A.
Nature Communications 13 (1): 7497. 5 December 2022

Cell type diversity in a developing octopus brain.
Styfhals, R. and Zolotarov, G. and Hulselmans, G. and Spanier, K.I. and Poovathingal, S. and Elagoz, A.M. and De Winter, S. and Deryckere, A. and Rajewsky, N. and Ponte, G. and Fiorito, G. and Aerts, S. and Seuntjens, E.
Nature Communications 13 (1): 7392. 30 November 2022

Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma.
Cichocki, F. and Bjordahl, R. and Goodridge, J.P. and Mahmood, S. and Gaidarova, S. and Abujarour, R. and Davis, Z.B. and Merino, A. and Tuininga, K. and Wang, H. and Kumar, A. and Groff, B. and Witty, A. and Bonello, G. and Huffman, J. and Dailey, T. and Lee, T.T. and Malmberg, K.J. and Walcheck, B. and Höpken, U. and Rehm, A. and Valamehr, B. and Miller, J.S.
Nature Communications 13 (1): 7341. 29 November 2022

DNA methylation-based classification of sinonasal tumors.
Jurmeister, P. and Glöß, S. and Roller, R. and Leitheiser, M. and Schmid, S. and Mochmann, L.H. and Payá Capilla, E. and Fritz, R. and Dittmayer, C. and Friedrich, C. and Thieme, A. and Keyl, P. and Jarosch, A. and Schallenberg, S. and Bläker, H. and Hoffmann, I. and Vollbrecht, C. and Lehmann, A. and Hummel, M. and Heim, D. and Haji, M. and Harter, P. and Englert, B. and Frank, S. and Hench, J. and Paulus, W. and Hasselblatt, M. and Hartmann, W. and Dohmen, H. and Keber, U. and Jank, P. and Denkert, C. and Stadelmann, C. and Bremmer, F. and Richter, A. and Wefers, A. and Ribbat-Idel, J. and Perner, S. and Idel, C. and Chiariotti, L. and Della Monica, R. and Marinelli, A. and Schüller, U. and Bockmayr, M. and Liu, J. and Lund, V.J. and Forster, M. and Lechner, M. and Lorenzo-Guerra, S.L. and Hermsen, M. and Johann, P.D. and Agaimy, A. and Seegerer, P. and Koch, A. and Heppner, F. and Pfister, S.M. and Jones, D.T.W. and Sill, M. and von Deimling, A. and Snuderl, M. and Müller, K.R. and Forgó, E. and Howitt, B.E. and Mertins, P. and Klauschen, F. and Capper, D.
Nature Communications 13 (1): 7148. 28 November 2022

Differential compartmentalization of myeloid cell phenotypes and responses towards the CNS in Alzheimer's disease.
Fernández Zapata, C. and Giacomello, G. and Spruth, E.J. and Middeldorp, J. and Gallaccio, G. and Dehlinger, A. and Dames, C. and Leman, J.K.H. and van Dijk, R.E. and Meisel, A. and Schlickeiser, S. and Kunkel, D. and Hol, E.M. and Paul, F. and Parr, M.K. and Priller, J. and Böttcher, C.
Nature Communications 13 (1): 7210. 23 November 2022

pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation.
Boix, O. and Martinez, M. and Vidal, S. and Giménez-Alejandre, M. and Palenzuela, L. and Lorenzo-Sanz, L. and Quevedo, L. and Moscoso, O. and Ruiz-Orera, J. and Ximénez-Embún, P. and Ciriaco, N. and Nuciforo, P. and Stephan-Otto Attolini, C. and Albà, M.M. and Muñoz, J. and Tian, T.V. and Varela, I. and Vivancos, A. and Ramón Y Cajal, S. and Muñoz, P. and Rivas, C. and Abad, M.
Nature Communications 13 (1): 6840. 11 November 2022

Molecular identity of proprioceptor subtypes innervating different muscle groups in mice.
Dietrich, S. and Company, C. and Song, K. and Lowenstein, E.D. and Riedel, L. and Birchmeier, C. and Gargiulo, G. and Zampieri, N.
Nature Communications 13 (1): 6867. 11 November 2022

Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation.
Ortiz-Zapater, E. and Bagley, D.C. and Hernandez, V.L. and Roberts, L.B. and Maguire, T.J.A. and Voss, F. and Mertins, P. and Kirchner, M. and Peset-Martin, I. and Woszczek, G. and Rosenblatt, J. and Gotthardt, M. and Santis, G. and Parsons, M.
Nature Communications 13 (1): 6407. 27 October 2022

Identifying interpretable gene-biomarker associations with functionally informed kernel-based tests in 190,000 exomes.
Monti, R. and Rautenstrauch, P. and Ghanbari, M. and James, A.R. and Kirchler, M. and Ohler, U. and Konigorski, S. and Lippert, C.
Nature Communications 13 (1): 5332. 10 September 2022

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation.
Zhou, D. and Borsa, M. and Puleston, D.J. and Zellner, S. and Capera, J. and Sanderson, S. and Schifferer, M. and Hester, S.S. and Ge, X. and Fischer, R. and Jostins, L. and Behrends, C. and Alsaleh, G. and Simon, A.K.
Nature Communications 13 (1): 5174. 2 September 2022

A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity.
Kedor, C. and Freitag, H. and Meyer-Arndt, L. and Wittke, K. and Hanitsch, L.G. and Zoller, T. and Steinbeis, F. and Haffke, M. and Rudolf, G. and Heidecker, B. and Bobbert, T. and Spranger, J. and Volk, H.D. and Skurk, C. and Konietschke, F. and Paul, F. and Behrends, U. and Bellmann-Strobl, J. and Scheibenbogen, C.
Nature Communications 13 (1): 5104. 30 August 2022

Unified classification and risk-stratification in Acute Myeloid Leukemia.
Tazi, Y. and Arango-Ossa, J.E. and Zhou, Y. and Bernard, E. and Thomas, I. and Gilkes, A. and Freeman, S. and Pradat, Y. and Johnson, S.J. and Hills, R. and Dillon, R. and Levine, M.F. and Leongamornlert, D. and Butler, A. and Ganser, A. and Bullinger, L. and Döhner, K. and Ottmann, O. and Adams, R. and Döhner, H. and Campbell, P.J. and Burnett, A.K. and Dennis, M. and Russell, N.H. and Devlin, S.M. and Huntly, B.J.P. and Papaemmanuil, E.
Nature Communications 13 (1): 4622. 8 August 2022

Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice.
Schepanski, S. and Chini, M. and Sternemann, V. and Urbschat, C. and Thiele, K. and Sun, T. and Zhao, Y. and Poburski, M. and Woestemeier, A. and Thieme, M.T. and Zazara, D.E. and Alawi, M. and Fischer, N. and Heeren, J. and Vladimirov, N. and Woehler, A. and Puelles, V.G. and Bonn, S. and Gagliani, N. and Hanganu-Opatz, I.L. and Arck, P.C.
Nature Communications 13 (1): 4571. 5 August 2022

Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Dorado Garcia, H. and Pusch, F. and Bei, Y. and von Stebut, J. and Ibáñez, G. and Guillan, K. and Imami, K. and Gürgen, D. and Rolff, J. and Helmsauer, K. and Meyer-Liesener, S. and Timme, N. and Bardinet, V. and Chamorro González, R. and MacArthur, I.C. and Chen, C.Y. and Schulz, J. and Wengner, A.M. and Furth, C. and Lala, B. and Eggert, A. and Seifert, G. and Hundsoerfer, P. and Kirchner, M. and Mertins, P. and Selbach, M. and Lissat, A. and Dubois, F. and Horst, D. and Schulte, J.H. and Spuler, S. and You, D. and Dela Cruz, F. and Kung, A.L. and Haase, K. and Di Virgilio, M. and Scheer, M. and Ortiz, M.V. and Henssen, A.G.
Nature Communications 13 (1): 4297. 25 July 2022

Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding.
Conte, M. and Irani, E. and Chiariello, A.M. and Abraham, A. and Bianco, S. and Esposito, A. and Nicodemi, M.
Nature Communications 13 (1): 4070. 13 July 2022

Temperature elevations can induce switches to homoclinic action potentials that alter neural encoding and synchronization.
Hesse, J. and Schleimer, J.H. and Maier, N. and Schmitz, D. and Schreiber, S.
Nature Communications 13 (1): 3934. 8 July 2022

Mafa-dependent GABAergic activity promotes mouse neonatal apneas.
Lecoin, L. and Dempsey, B. and Garancher, A. and Bourane, S. and Ruffault, P.L. and Morin-Surun, M.P. and Rocques, N. and Goulding, M. and Eychène, A. and Pouponnot, C. and Fortin, G. and Champagnat, J.
Nature Communications 13 (1): 3284. 7 June 2022

Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth.
Dzamukova, M. and Brunner, T.M. and Miotla-Zarebska, J. and Heinrich, F. and Brylka, L. and Mashreghi, M.F. and Kusumbe, A. and Kühn, R. and Schinke, T. and Vincent, T.L.. and Löhning, M.
Nature Communications 13 (1): 3059. 1 June 2022

Serotonin limits generation of chromaffin cells during adrenal organ development.
Kameneva, P. and Melnikova, V.I. and Kastriti, M.E. and Kurtova, A. and Kryukov, E. and Murtazina, A. and Faure, L. and Poverennaya, I. and Artemov, A.V. and Kalinina, T.S. and Kudryashov, N.V. and Bader, M. and Skoda, J. and Chlapek, P. and Curylova, L. and Sourada, L. and Neradil, J. and Tesarova, M. and Pasqualetti, M. and Gaspar, P. and Yakushov, V.D. and Sheftel, B.I. and Zikmund, T. and Kaiser, J. and Fried, K. and Alenina, N. and Voronezhskaya, E.E. and Adameyko, I.
Nature Communications 13 (1): 2901. 25 May 2022

HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.
Zinnall, U. and Milek, M. and Minia, I. and Vieira-Vieira, C.H. and Müller, S. and Mastrobuoni, G. and Hazapis, O.G. and Del Giudice, S. and Schwefel, D. and Bley, N. and Voigt, F. and Chao, J.A. and Kempa, S. and Hüttelmaier, S. and Selbach, M. and Landthaler, M.
Nature Communications 13 (1): 2727. 18 May 2022

The genomic and transcriptional landscape of primary central nervous system lymphoma.
Radke, J. and Ishaque, N. and Koll, R. and Gu, Z. and Schumann, E. and Sieverling, L. and Uhrig, S. and Hübschmann, D. and Toprak, U.H. and López, C. and Hostench, X.P. and Borgoni, S. and Juraeva, D. and Pritsch, F. and Paramasivam, N. and Balasubramanian, G.P. and Schlesner, M. and Sahay, S. and Weniger, M. and Pehl, D. and Radbruch, H. and Osterloh, A. and Korfel, A. and Misch, M. and Onken, J. and Faust, K. and Vajkoczy, P. and Moskopp, D. and Wang, Y. and Jödicke, A. and Trümper, L. and Anagnostopoulos, I. and Lenze, D. and Küppers, R. and Hummel, M. and Schmitt, C.A. and Wiestler, O.D. and Wolf, S. and Unterberg, A. and Eils, R. and Herold-Mende, C. and Brors, B. and Siebert, R. and Wiemann, S. and Heppner, F.L.
Nature Communications 13 (1): 2558. 10 May 2022

USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer.
Nelson, J.K. and Thin, M.Z. and Evan, T. and Howell, S. and Wu, M. and Almeida, B. and Legrave, N. and Koenis, D. S. and Koifman, G. and Sugimoto, Y. and Llorian Sopena, M. and MacRae, J. and Nye, E. and Howell, M. and Snijders, A.P. and Prachalias, A. and Zen, Y. and Sarker, D. and Behrens, A.
Nature Communications 13 (1): 2070. 19 April 2022

BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.
Kapalczynska, M. and Lin, M. and Maertzdorf, J. and Heuberger, J. and Muellerke, S. and Zuo, X. and Vidal, R. and Shureiqi, I. and Fischer, A.S. and Sauer, S. and Berger, H. and Kidess, E. and Mollenkopf, H.J. and Tacke, F. and Meyer, T.F. and Sigal, M.
Nature Communications 13 (1): 1577. 24 March 2022

The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.
Günes Günsel, G. and Conlon, T.M. and Jeridi, A. and Kim, R. and Ertüz, Z. and Lang, N.J. and Ansari, M. and Novikova, M. and Jiang, D. and Strunz, M. and Gaianova, M. and Hollauer, C. and Gabriel, C. and Angelidis, I. and Doll, S. and Pestoni, J.C. and Edelmann, S.L. and Kohlhepp, M.S. and Guillot, A. and Bassler, K. and Van Eeckhoutte, H.P. and Kayalar, Ö. and Konyalilar, N. and Kanashova, T. and Rodius, S. and Ballester-López, C. and Genes Robles, C.M. and Smirnova, N. and Rehberg, M. and Agarwal, C. and Krikki, I. and Piavaux, B. and Verleden, S.E. and Vanaudenaerde, B. and Königshoff, M. and Dittmar, G. and Bracke, K.R. and Schultze, J.L. and Watz, H. and Eickelberg, O. and Stoeger, T. and Burgstaller, G. and Tacke, F. and Heissmeyer, V. and Rinkevich, Y. and Bayram, H. and Schiller, H.B. and Conrad, M. and Schneider, R. and Yildirim, A.Ö.
Nature Communications 13 (1): 1303. 14 March 2022

Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity.
Cabral-Marques, O. and Halpert, G. and Schimke, L.F. and Ostrinski, Y. and Vojdani, A. and Baiocchi, G.C. and Freire, P.P. and Filgueiras, I.S. and Zyskind, I. and Lattin, M.T. and Tran, F. and Schreiber, S. and Marques, A.H.C. and Plaça, D.R. and Fonseca, D.L.M. and Humrich, J.Y. and Müller, A. and Giil, L.M. and Graßhoff, H. and Schumann, A. and Hackel, A. and Junker, J. and Meyer, C. and Ochs, H.D. and Lavi, Y.B. and Scheibenbogen, C. and Dechend, R. and Jurisica, I. and Schulze-Forster, K. and Silverberg, J.I. and Amital, H. and Zimmerman, J. and Heidecke, H. and Rosenberg, A.Z. and Riemekasten, G. and Shoenfeld, Y.
Nature Communications 13 (1): 1220. 9 March 2022

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng, Y.L.D. and Ramberger, E. and Bohl, S.R. and Dolnik, A. and Steinebach, C. and Conrad, T. and Müller, S. and Popp, O. and Kull, M. and Haji, M. and Gütschow, M. and Döhner, H. and Walther, W. and Keller, U. and Bullinger, L. and Mertins, P. and Krönke, J.
Nature Communications 13 (1): 1009. 23 February 2022

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.
Pekayvaz, K. and Leunig, A. and Kaiser, R. and Joppich, M. and Brambs, S. and Janjic, A. and Popp, O. and Nixdorf, D. and Fumagalli, V. and Schmidt, N. and Polewka, V. and Anjum, A. and Knottenberg, V. and Eivers, L. and Wange, L.E. and Gold, C. and Kirchner, M. and Muenchhoff, M. and Hellmuth, J.C. and Scherer, C. and Rubio-Acero, R. and Eser, T. and Deák, F. and Puchinger, K. and Kuhl, N. and Linder, A. and Saar, K. and Tomas, L. and Schulz, C. and Wieser, A. and Enard, W. and Kroidl, I. and Geldmacher, C. and von Bergwelt-Baildon, M. and Keppler, O.T. and Munschauer, M. and Iannacone, M. and Zimmer, R. and Mertins, P. and Hubner, N. and Hoelscher, M. and Massberg, S. and Stark, K. and Nicolai, L.
Nature Communications 13 (1): 1018. 23 February 2022

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.
Schick, M. and Zhang, L. and Maurer, S. and Maurer, H.C. and Isaakaidis, K. and Schneider, L. and Patra, U. and Schunck, K. and Rohleder, E. and Hofstetter, J. and Baluapuri, A. and Scherger, A.K. and Slotta-Huspenina, J. and Hettler, F. and Weber, J. and Engleitner, T. and Maresch, R. and Slawska, J. and Lewis, R. and Istvanffy, R. and Habringer, S. and Steiger, K. and Baiker, A. and Oostendorp, R.A.J. and Miething, C. and Lenhof, H.P. and Bassermann, F. and Chapuy, B. and Wirth, M. and Wolf, E. and Rad, R. and Müller, S. and Keller, U.
Nature Communications 13 (1): 281. 12 January 2022

Skeletal muscle derived Musclin protects the heart during pathological overload.
Szaroszyk, M. and Kattih, B. and Martin-Garrido, A. and Trogisch, F.A. and Dittrich, G.M. and Grund, A. and Abouissa, A. and Derlin, K. and Meier, M. and Holler, T. and Korf-Klingebiel, M. and Völker, K. and Macedo, T.G. and Tortola, C.P. and Boschmann, M. and Huang, N. and Froese, N. and Zwadlo, C. and Malek Mohammadi, M. and Luo, X. and Wagner, M. and Cordero, J. and Geffers, R. and Batkai, S. and Thum, T. and Bork, N. and Nikolaev, V.O. and Müller, O.J. and Katus, H.A. and El-Armouche, A. and Kraft, T. and Springer, J. and Dobreva, G. and Wollert, K.C. and Fielitz, J. and von Haehling, S. and Kuhn, M. and Bauersachs, J. and Heineke, J.
Nature Communications 13 (1): 149. 10 January 2022

RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation.
Poetz, F. and Corbo, J. and Levdansky, Y. and Spiegelhalter, A. and Lindner, D. and Magg, V. and Lebedeva, S. and Schweiggert, J. and Schott, J. and Valkov, E. and Stoecklin, G.
Nature Communications 12 (1): 7175. 9 December 2021

Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions.
Schmelz, K. and Toedling, J. and Huska, M. and Cwikla, M.C. and Kruetzfeldt, L.M. and Proba, J. and Ambros, P.F. and Ambros, I.M. and Boral, S. and Lodrini, M. and Chen, C.Y. and Burkert, M. and Guergen, D. and Szymansky, A. and Astrahantseff, K. and Kuenkele, A. and Haase, K. and Fischer, M. and Deubzer, H.E. and Hertwig, F. and Hundsdoerfer, P. and Henssen, A.G. and Schwarz, R.F. and Schulte, J.H. and Eggert, A.
Nature Communications 12 (1): 6804. 23 November 2021

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities.
Kruse, T. and Benz, C. and Garvanska, D.H. and Lindqvist, R. and Mihalic, F. and Coscia, F. and Inturi, R. and Sayadi, A. and Simonetti, L. and Nilsson, E. and Ali, M. and Kliche, J. and Moliner Morro, A. and Mund, A. and Andersson, E. and McInerney, G. and Mann, M. and Jemth, P. and Davey, N.E. and Överby, A.K. and Nilsson, J. and Ivarsson, Y.
Nature Communications 12 (1): 6761. 19 November 2021

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.
Geusz, R.J. and Wang, A. and Lam, D.K. and Vinckier, N.K. and Alysandratos, K.D. and Roberts, D.A. and Wang, J. and Kefalopoulou, S. and Ramirez, A. and Qiu, Y. and Chiou, J. and Gaulton, K.J. and Ren, B. and Kotton, D.N. and Sander, M.
Nature Communications 12 (1): 6636. 17 November 2021

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4.
Grosche, S. and Marenholz, I. and Esparza-Gordillo, J. and Arnau-Soler, A. and Pairo-Castineira, E. and Rüschendorf, F. and Ahluwalia, T.S. and Almqvist, C. and Arnold, A. and Baurecht, H. and Bisgaard, H. and Bønnelykke, K. and Brown, S.J. and Bustamante, M. and Curtin, J.A. and Custovic, A. and Dharmage, S.C. and Esplugues, A. and Falchi, M. and Fernandez-Orth, D. and Ferreira, M.A.R. and Franke, A. and Gerdes, S. and Gieger, C. and Hakonarson, H. and Holt, P.G. and Homuth, G. and Hubner, N. and Hysi, P.G. and Jarvelin, M.R. and Karlsson, R. and Koppelman, G.H. and Lau, S. and Lutz, M. and Magnusson, P.K.E. and Marks, G.B. and Müller-Nurasyid, M. and Nöthen, M.M. and Paternoster, L. and Pennell, C.E. and Peters, A. and Rawlik, K. and Robertson, C.F. and Rodriguez, E. and Sebert, S. and Simpson, A. and Sleiman, P.M.A. and Standl, M. and Stölzl, D. and Strauch, K. and Szwajda, A. and Tenesa, A. and Thompson, P.J. and Ullemar, V. and Visconti, A. and Vonk, J.M. and Wang, C.A. and Weidinger, S. and Wielscher, M. and Sargent, C.L. and Xu, C.J. and Lee, Y.A.
Nature Communications 12 (1): 6618. 16 November 2021

Lysine acetylation regulates the interaction between proteins and membranes.
Okada, A.K. and Teranishi, K. and Ambroso, M.R. and Isas, J.M. and Vazquez-Sarandeses, E. and Lee, J.Y. and Melo, A.A. and Pandey, P. and Merken, D. and Berndt, L. and Lammers, M. and Daumke, O. and Chang, K. and Haworth, I.S. and Langen, R.
Nature Communications 12 (1): 6466. 9 November 2021

A medullary centre for lapping in mice.
Dempsey, B. and Sungeelee, S. and Bokiniec, P. and Chettouh, Z. and Diem, S. and Autran, S. and Harrell, E.R. and Poulet, J.F.A. and Birchmeier, C. and Carey, H. and Genovesio, A. and McMullan, S. and Goridis, C. and Fortin, G. and Brunet, J.F.
Nature Communications 12 : 6307. 2 November 2021

PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.
Appel, L.M. and Franke, V. and Bruno, M. and Grishkovskaya, I. and Kasiliauskaite, A. and Kaufmann, T. and Schoeberl, U.E. and Puchinger, M.G. and Kostrhon, S. and Ebenwaldner, C. and Sebesta, M. and Beltzung, E. and Mechtler, K. and Lin, G. and Vlasova, A. and Leeb, M. and Pavri, R. and Stark, A. and Akalin, A. and Stefl, R. and Bernecky, C. and Djinovic-Carugo, K. and Slade, D.
Nature Communications 12 (1): 6078. 19 October 2021

Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma.
Liang, H.C. and Costanza, M. and Prutsch, N. and Zimmerman, M.W. and Gurnhofer, E. and Montes-Mojarro, I.A. and Abraham, B.J. and Prokoph, N. and Stoiber, S. and Tangermann, S. and Lobello, C. and Oppelt, J. and Anagnostopoulos, I. and Hielscher, T. and Pervez, S. and Klapper, W. and Zammarchi, F. and Silva, D.A. and Garcia, K.C. and Baker, D. and Janz, M. and Schleussner, N. and Fend, F. and Pospíšilová, Š. and Janiková, A. and Wallwitz, J. and Stoiber, D. and Simonitsch-Klupp, I. and Cerroni, L. and Pileri, S. and de Leval, L. and Sibon, D. and Fataccioli, V. and Gaulard, P. and Assaf, C. and Knörr, F. and Damm-Welk, C. and Woessmann, W. and Turner, S.D. and Look, A.T. and Mathas, S. and Kenner, L. and Merkel, O.
Nature Communications 12 (1): 5577. 22 September 2021

MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Brägelmann, J. and Lorenz, C. and Borchmann, S. and Nishii, K. and Wegner, J. and Meder, L. and Ostendorp, J. and Ast, D.F. and Heimsoeth, A. and Nakasuka, T. and Hirabae, A. and Okawa, S. and Dammert, M.A. and Plenker, D. and Klein, S. and Lohneis, P. and Gu, J. and Godfrey, L.K. and Forster, J. and Trajkovic-Arsic, M. and Zillinger, T. and Haarmann, M. and Quaas, A. and Lennartz, S. and Schmiel, M. and D'Rozario, J. and Thomas, E.S. and Li, H. and Schmitt, C.A. and George, J. and Thomas, R.K. and von Karstedt, S. and Hartmann, G. and Büttner, R. and Ullrich, R.T. and Siveke, J.T. and Ohashi, K. and Schlee, M. and Sos, M.L.
Nature Communications 12 (1): 5505. 17 September 2021

Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.
Bloehdorn, J. and Braun, A. and Taylor-Weiner, A. and Jebaraj, B.M.C. and Robrecht, S. and Krzykalla, J. and Pan, H. and Giza, A. and Akylzhanova, G. and Holzmann, K. and Scheffold, A. and Johnston, H.E. and Yeh, R.F. and Klymenko, T. and Tausch, E. and Eichhorst, B. and Bullinger, L. and Fischer, K. and Weisser, M. and Robak, T. and Schneider, C. and Gribben, J. and Dahal, L.N. and Carter, M.J. and Elemento, O. and Landau, D.A. and Neuberg, D.S. and Cragg, M.S. and Benner, A. and Hallek, M. and Wu, C.J. and Döhner, H. and Stilgenbauer, S. and Mertens, D.
Nature Communications 12 (1): 5395. 13 September 2021

CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression.
Franke, M. and De la Calle-Mustienes, E. and Neto, A. and Almuedo-Castillo, M. and Irastorza-Azcarate, I. and Acemel, R.D. and Tena, J.J. and Santos-Pereira, J.M. and Gómez-Skarmeta, J.L.
Nature Communications 12 (1): 5415. 13 September 2021

Locus specific epigenetic modalities of random allelic expression imbalance.
Marion-Poll, L. and Forêt, B. and Zielinski, D. and Massip, F. and Attia, M. and Carter, A.C. and Syx, L. and Chang, H.Y. and Gendrel, A.V. and Heard, E.
Nature Communications 12 (1): 5330. 9 September 2021

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4.
Diener, J. and Baggiolini, A. and Pernebrink, M. and Dalcher, D. and Lerra, L. and Cheng, P.F. and Varum, S. and Häusel, J. and Stierli, S. and Treier, M. and Studer, L. and Basler, K. and Levesque, M.P. and Dummer, R. and Santoro, R. and Cantù, C. and Sommer, L.
Nature Communications 12 (1): 5056. 20 August 2021

A simple pressure-assisted method for MicroED specimen preparation.
Zhao, J. and Xu, H. and Lebrette, H. and Carroni, M. and Taberman, H. and Högbom, M. and Zou, X.
Nature Communications 12 (1): 5036. 19 August 2021

Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19.
Nouailles, G. and Wyler, E. and Pennitz, P. and Postmus, D. and Vladimirova, D. and Kazmierski, J. and Pott, F. and Dietert, K. and Muelleder, M. and Farztdinov, V. and Obermayer, B. and Wienhold, S.M. and Andreotti, S. and Hoefler, T. and Sawitzki, B. and Drosten, C. and Sander, L.E. and Suttorp, N. and Ralser, M. and Beule, D. and Gruber, A.D. and Goffinet, C. and Landthaler, M. and Trimpert, J. and Witzenrath, M.
Nature Communications 12 (1): 4869. 11 August 2021

Place fields of single spikes in hippocampus involve Kcnq3 channel-dependent entrainment of complex spike bursts.
Gao, X. and Bender, F. and Soh, H. and Chen, C. and Altafi, M. and Schütze, S. and Heidenreich, M. and Gorbati, M. and Corbu, M.A. and Carus-Cadavieco, M. and Korotkova, T. and Tzingounis, A.V. and Jentsch, T.J. and Ponomarenko, A.
Nature Communications 12 (1): 4801. 10 August 2021

SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity.
Boehm, V. and Kueckelmann, S. and Gerbracht, J.V. and Kallabis, S. and Britto-Borges, T. and Altmüller, J. and Krüger, M. and Dieterich, C. and Gehring, N.H.
Nature Communications 12 (1): 3965. 25 June 2021

Post-myocardial infarction heart failure dysregulates the bone vascular niche.
Hoffmann, J. and Luxán, G. and Abplanalp, W.T. and Glaser, S.F. and Rasper, T. and Fischer, A. and Muhly-Reinholz, M. and Potente, M. and Assmus, B. and John, D. and Zeiher, A.M. and Dimmeler, S.
Nature Communications 12 (1): 3964. 25 June 2021

SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Gassen, N.C. and Papies, J. and Bajaj, T. and Emanuel, J. and Dethloff, F. and Chua, R.L. and Trimpert, J. and Heinemann, N. and Niemeyer, C. and Weege, F. and Hönzke, K. and Aschman, T. and Heinz, D.E. and Weckmann, K. and Ebert, T. and Zellner, A. and Lennarz, M. and Wyler, E. and Schroeder, S. and Richter, A. and Niemeyer, D. and Hoffmann, K. and Meyer, T.F. and Heppner, F.L. and Corman, V.M. and Landthaler, M. and Hocke, A.C. and Morkel, M. and Osterrieder, N. and Conrad, C. and Eils, R. and Radbruch, H. and Giavalisco, P. and Drosten, C. and Müller, M.A.
Nature Communications 12 (1): 3818. 21 June 2021

Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories.
Friedrich, C. and Schallenberg, S. and Kirchner, M. and Ziehm, M. and Niquet, S. and Haji, M. and Beier, C. and Neudecker, J. and Klauschen, F. and Mertins, P.
Nature Communications 12 (1): 3576. 11 June 2021

Spatio-temporal mRNA tracking in the early zebrafish embryo.
Holler, K. and Neuschulz, A. and Drewe-Boß, P. and Mintcheva, J. and Spanjaard, B. and Arsiè, R. and Ohler, U. and Landthaler, M. and Junker, J.P.
Nature Communications 12 : 3358. 7 June 2021

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
de Rojas, I. and Moreno-Grau, S. and Tesi, N. and Grenier-Boley, B. and Andrade, V. and Jansen, I.E. and Pedersen, N.L. and Stringa, N. and Zettergren, A. and Hernández, I. and Montrreal, L. and Antúnez, C. and Antonell, A. and Tankard, R.M. and Bis, J.C. and Sims, R. and Bellenguez, C. and Quintela, I. and González-Perez, A. and Calero, M. and Franco-Macías, E. and Macías, J. and Blesa, R. and Cervera-Carles, L. and Menéndez-González, M. and Frank-García, A. and Royo, J.L. and Moreno, F. and Huerto Vilas, R. and Baquero, M. and Diez-Fairen, M. and Lage, C. and García-Madrona, S. and García-González, P. and Alarcón-Martín, E. and Valero, S. and Sotolongo-Grau, O. and Ullgren, A. and Naj, A.C. and Lemstra, A.W. and Benaque, A. and Pérez-Cordón, A. and Benussi, A. and Rábano, A. and Padovani, A. and Squassina, A. and de Mendonça, A. and Arias Pastor, A. and Kok, A.A.L. and Meggy, A. and Pastor, A.B. and Espinosa, A. and Corma-Gómez, A. and Martín Montes, A. and Sanabria, Á. and DeStefano, A.L. and Schneider, A. and Haapasalo, A. and Kinhult Ståhlbom, A. and Tybjærg-Hansen, A. and Hartmann, A.M. and Spottke, A. and Corbatón-Anchuelo, A. and Rongve, A. and Borroni, B. and Arosio, B. and Nacmias, B. and Nordestgaard, B.G. and Kunkle, B.W. and Charbonnier, C. and Abdelnour, C. and Masullo, C. and Martínez Rodríguez, C. and Muñoz-Fernandez, C. and Dufouil, C. and Graff, C. and Ferreira, C.B. and Chillotti, C. and Reynolds, C.A. and Fenoglio, C. and Van Broeckhoven, C. and Clark, C. and Pisanu, C. and Satizabal, C.L. and Holmes, C. and Buiza-Rueda, D. and Aarsland, D. and Rujescu, D. and Alcolea, D. and Galimberti, D. and Wallon, D. and Seripa, D. and Grünblatt, E. and Dardiotis, E. and Düzel, E. and Scarpini, E. and Conti, E. and Rubino, E. and Gelpi, E. and Rodriguez-Rodriguez, E. and Duron, E. and Boerwinkle, E. and Ferri, E. and Tagliavini, F. and Küçükali, F. and Pasquier, F. and Sanchez-Garcia, F. and Mangialasche, F. and Jessen, F. and Nicolas, G. and Selbæk, G. and Ortega, G. and Chêne, G. and Hadjigeorgiou, G. and Rossi, G. and Spalletta, G. and Giaccone, G. and Grande, G. and Binetti, G. and Papenberg, G. and Hampel, H. and Bailly, H. and Zetterberg, H. and Soininen, H. and Karlsson, I.K. and Alvarez, I. and Appollonio, I. and Giegling, I. and Skoog, I. and Saltvedt, I. and Rainero, I. and Rosas Allende, I. and Hort, J. and Diehl-Schmid, J. and Van Dongen, J. and Vidal, J.S. and Lehtisalo, J. and Wiltfang, J. and Thomassen, J.Q. and Kornhuber, J. and Haines, J.L. and Vogelgsang, J. and Pineda, J.A. and Fortea, J. and Popp, J. and Deckert, J. and Buerger, K. and Morgan, K. and Fließbach, K. and Sleegers, K. and Molina-Porcel, L. and Kilander, L. and Weinhold, L. and Farrer, L.A. and Wang, L.S. and Kleineidam, L. and Farotti, L. and Parnetti, L. and Tremolizzo, L. and Hausner, L. and Benussi, L. and Froelich, L. and Ikram, M.A. and Deniz-Naranjo, M.C. and Tsolaki, M. and Rosende-Roca, M. and Löwenmark, M. and Hulsman, M. and Spallazzi, M. and Pericak-Vance, M.A. and Esiri, M. and Bernal Sánchez-Arjona, M. and Dalmasso, M.C. and Martínez-Larrad, M.T. and Arcaro, M. and Nöthen, M.M. and Fernández-Fuertes, M. and Dichgans, M. and Ingelsson, M. and Herrmann, M.J. and Scherer, M. and Vyhnalek, M. and Kosmidis, M.H. and Yannakoulia, M. and Schmid, M. and Ewers, M. and Heneka, M.T. and Wagner, M. and Scamosci, M. and Kivipelto, M. and Hiltunen, M. and Zulaica, M. and Alegret, M. and Fornage, M. and Roberto, N. and van Schoor, N.M. and Seidu, N.M. and Banaj, N. and Armstrong, N.J. and Scarmeas, N. and Scherbaum, N. and Goldhardt, O. and Hanon, O. and Peters, O. and Skrobot, O.A. and Quenez, O. and Lerch, O. and Bossù, P. and Caffarra, P. and Dionigi Rossi, P. and Sakka, P. and Mecocci, P. and Hoffmann, P. and Holmans, P.A. and Fischer, P. and Riederer, P. and Yang, Q. and Marshall, R. and Kalaria, R.N. and Mayeux, R. and Vandenberghe, R. and Cecchetti, R. and Ghidoni, R. and Frikke-Schmidt, R. and Sorbi, S. and Hägg, S. and Engelborghs, S. and Helisalmi, S. and Botne Sando, S. and Kern, S. and Archetti, S. and Boschi, S. and Fostinelli, S. and Gil, S. and Mendoza, S. and Mead, S. and Ciccone, S. and Djurovic, S. and Heilmann-Heimbach, S. and Riedel-Heller, S. and Kuulasmaa, T. and Del Ser, T. and Lebouvier, T. and Polak, T. and Ngandu, T. and Grimmer, T. and Bessi, V. and Escott-Price, V. and Giedraitis, V. and Deramecourt, Vi. and Maier, W. and Jian, X. and Pijnenburg, Y.A.L. and Kehoe, P.G. and Garcia-Ribas, G. and Sánchez-Juan, P. and Pastor, P. and Pérez-Tur, J. and Piñol-Ripoll, G. and Lopez de Munain, A. and García-Alberca, J.M. and Bullido, M.J. and Álvarez, V. and Lleó, A. and Real, L.M. and Mir, P. and Medina, M. and Scheltens, P. and Holstege, H. and Marquié, M. and Sáez, M.E. and Carracedo, Á. and Amouyel, P. and Schellenberg, G.D. and Williams, J. and Seshadri, S. and van Duijn, C.M. and Mather, K.A. and Sánchez-Valle, R. and Serrano-Ríos, M. and Orellana, A. and Tárraga, L. and Blennow, K. and Huisman, M. and Andreassen, O.A. and Posthuma, D. and Clarimón, J. and Boada, M. and van der Flier, W.M. and Ramirez, A. and Lambert, J.C. and van der Lee, S.J. and Ruiz, A.
Nature Communications 12 (1): 3417. 7 June 2021

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network.
Grapotte, M. and Saraswat, M. and Bessière, C. and Menichelli, C. and Ramilowski, J.A. and Severin, J. and Hayashizaki, Y. and Itoh, M. and Tagami, M. and Murata, M. and Kojima-Ishiyama, M. and Noma, S. and Noguchi, S. and Kasukawa, T. and Hasegawa, A. and Suzuki, H. and Nishiyori-Sueki, H. and Frith, M.C. and Chatelain, C. and Carninci, P. and de Hoon, M.J.L. and Wasserman, W.W. and Bréhélin, L. and Lecellier, C.H.
Nature Communications 12 (1): 3297. 2 June 2021

EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells.
Roy, S. and Rizvi, Z.A. and Clarke, A.J. and Macdonald, F. and Pandey, A. and Zaiss, D.M.W. and Simon, A.K. and Awasthi, A.
Nature Communications 12 (1): 3182. 1 June 2021

Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology.
Kargapolova, Y. and Rehimi, R. and Kayserili, H. and Brühl, J. and Sofiadis, K. and Zirkel, A. and Palikyras, S. and Mizi, A. and Li, Y. and Yigit, G. and Hoischen, A. and Frank, S. and Russ, N. and Trautwein, J. and van Bon, B. and Gilissen, C. and Laugsch, M. and Gusmao, E.G. and Josipovic, N. and Altmüller, J. and Nürnberg, P. and Längst, G. and Kaiser, F.J. and Watrin, E. and Brunner, H. and Rada-Iglesias, A. and Kurian, L. and Wollnik, B. and Bouazoune, K. and Papantonis, A.
Nature Communications 12 (1): 3014. 21 May 2021

Asymmetric cell division shapes naive and virtual memory T-cell immunity during ageing.
Borsa, M. and Barandun, N. and Gräbnitz, F. and Barnstorf, I. and Baumann, N.S. and Pallmer, K. and Baumann, S. and Stark, D. and Balaz, M. and Oetiker, N. and Wagen, F. and Wolfrum, C. and Simon, A.K. and Joller, N. and Barral, Y. and Spörri, R. and Oxenius, A.
Nature Communications 12 (1): 2715. 11 May 2021

Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients.
Maifeld, A. and Bartolomaeus, H. and Löber, U. and Avery, E.G. and Steckhan, N. and Markó, L. and Wilck, N. and Hamad, I. and Šušnjar, U. and Mähler, A. and Hohmann, C. and Chen, C.Y. and Cramer, H. and Dobos, G. and Lesker, T.R. and Strowig, T. and Dechend, R. and Bzdok, D. and Kleinewietfeld, M. and Michalsen, A. and Müller, D.N. and Forslund, S.K.
Nature Communications 12 (1): 1970. 30 March 2021

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak, G. and Rybak-Wolf, A. and Lisowski, P. and Pentimalli, T.M. and Jüttner, R. and Glažar, P. and Uppal, K. and Bottani, E. and Brunetti, D. and Secker, C. and Zink, A. and Meierhofer, D. and Henke, M.T. and Dey, M. and Ciptasari, U. and Mlody, B. and Hahn, T. and Berruezo-Llacuna, M. and Karaiskos, N. and Di Virgilio, M. and Mayr, J.A. and Wortmann, S.B. and Priller, J. and Gotthardt, M. and Jones, D.P. and Mayatepek, E. and Stenzel, W. and Diecke, S. and Kühn, R. and Wanker, E.E. and Rajewsky, N. and Schuelke, M. and Prigione, A.
Nature Communications 12 (1): 1929. 26 March 2021

Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ejection fraction.
Schiattarella, G.G. and Altamirano, F. and Kim, S.Y. and Tong, D. and Ferdous, A. and Piristine, H. and Dasgupta, S. and Wang, X. and French, K.M. and Villalobos, E. and Spurgin, S.B. and Waldman, M. and Jiang, N. and May, H.I. and Hill, T.M. and Luo, Y. and Yoo, H. and Zaha, V.G. and Lavandero, S. and Gillette, T.G. and Hill, J.A.
Nature Communications 12 (1): 1684. 16 March 2021

Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics.
Velten, L. and Story, B.A. and Hernández-Malmierca, P. and Raffel, S. and Leonce, D.R. and Milbank, J. and Paulsen, M. and Demir, A. and Szu-Tu, C. and Frömel, R. and Lutz, C. and Nowak, D. and Jann, J.C. and Pabst, C. and Boch, T. and Hofmann, W.K. and Müller-Tidow, C. and Trumpp, A. and Haas, S. and Steinmetz, L.M.
Nature Communications 12 (1): 1366. 1 March 2021

Oscillations of Delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells.
Zhang, Y. and Lahmann, I. and Baum, K. and Shimojo, H. and Mourikis, P. and Wolf, J. and Kageyama, R. and Birchmeier, C.
Nature Communications 12 (1): 1318. 26 February 2021

Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Hartlieb, S.A. and Sieverling, L. and Nadler-Holly, M. and Ziehm, M. and Toprak, U.H. and Herrmann, C. and Ishaque, N. and Okonechnikov, K. and Gartlgruber, M. and Park, Y.G. and Wecht, E.M. and Savelyeva, L. and Henrich, K.O. and Rosswog, C. and Fischer, M. and Hero, B. and Jones, D.T.W. and Pfaff, E. and Witt, O. and Pfister, S.M. and Volckmann, Ri. and Koster, J. and Kiesel, K. and Rippe, K. and Taschner-Mandl, S. and Ambros, P. and Brors, B. and Selbach, M. and Feuerbach, L. and Westermann, F.
Nature Communications 12 (1): 1269. 24 February 2021

Asymmetric opening of the homopentameric 5-HT(3A) serotonin receptor in lipid bilayers.
Zhang, Y. and Dijkman, P.M. and Zou, R. and Zandl-Lang, M. and Sanchez, R.M. and Eckhardt-Strelau, L. and Köfeler, H. and Vogel, H. and Yuan, S. and Kudryashev, M.
Nature Communications 12 (1): 1074. 16 February 2021

Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.
Iftekhar, A. and Berger, H. and Bouznad, N. and Heuberger, J. and Boccellato, F. and Dobrindt, U. and Hermeking, H. and Sigal, M. and Meyer, T.F.
Nature Communications 12 (1): 1003. 12 February 2021

Uncovering de novo gene birth in yeast using deep transcriptomics.
Blevins, W.R. and Ruiz-Orera, J. and Messeguer, X. and Blasco-Moreno, B. and Villanueva-Cañas, J.L. and Espinar, L. and Díez, J. and Carey, L.B. and Albà, M.M.
Nature Communications 12 (1): 604. 27 January 2021

Endophilin A2 deficiency protects rodents from autoimmune arthritis by modulating T cell activation.
Norin, U. and Rintisch, C. and Meng, L. and Forster, F. and Ekman, D. and Tuncel, J. and Klocke, K. and Bäcklund, J. and Yang, M. and Bonner, M.Y and Lahore, G.F. and James, J. and Shchetynsky, K. and Bergquist, M. and Gjertsson, I. and Hubner, N. and Bäckdahl, L. and Holmdahl, R.
Nature Communications 12 (1): 610. 27 January 2021

Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington's disease mice.
Alcalá-Vida, R. and Seguin, J. and Lotz, C. and Molitor, A.M. and Irastorza-Azcarate, I. and Awada, A. and Karasu, N. and Bombardier, A. and Cosquer, B. and Skarmeta, J.L.G. and Cassel, J.C. and Boutillier, A.L. and Sexton, T. and Merienne, K.
Nature Communications 12 (1): 364. 13 January 2021

CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin's lymphoma and tumor-supportive follicular T helper cells.
Bunse, M. and Pfeilschifter, J. and Bluhm, J. and Zschummel, M. and Joedicke, J.J. and Wirges, A. and Stark, H. and Kretschmer, V. and Chmielewski, M. and Uckert, W. and Abken, H. and Westermann, J. and Rehm, A. and Höpken, U.E.
Nature Communications 12 (1): 240. 11 January 2021

The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Grinat, J. and Heuberger, J. and Vidal, R. and Goveas, N. and Kosel, F. and Berenguer-Llergo, A. and Kranz, A. and Wulf-Goldenberg, A. and Behrens, D. and Melcher, B. and Sauer, S. and Vieth, M. and Batlle, E. and Stewart, A. and Birchmeier, W.
Nature Communications 11 (1): 6422. 21 December 2020

Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells.
Kim, M. and Franke, V. and Brandt, B. and Lowenstein, E.D. and Schöwel, V. and Spuler, S. and Akalin, A. and Birchmeier, C.
Nature Communications 11 : 6375. 11 December 2020

Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology.
Molinaro, A. and Bel Lassen, P. and Henricsson, M. and Wu, H. and Adriouch, S. and Belda, E. and Chakaroun, R. and Nielsen, T. and Bergh, P.O. and Rouault, C. and André, S. and Marquet, F. and Andreelli, F. and Salem, J.E. and Assmann, K. and Bastard, J.P. and Forslund, S. and Le Chatelier, E. and Falony, G. and Pons, N. and Prifti, E. and Quinquis, B. and Roume, H. and Vieira-Silva, S. and Hansen, T.H. and Pedersen, H.K. and Lewinter, C. and Sønderskov, N.B. and Køber, L. and Vestergaard, H. and Hansen, T. and Zucker, J.D. and Galan, P. and Dumas, M.E. and Raes, J. and Oppert, J.M. and Letunic, I. and Nielsen, J. and Bork, P. and Ehrlich, S.D. and Stumvoll, M. and Pedersen, O. and Aron-Wisnewsky, J. and Clément, K. and Bäckhed, F.
Nature Communications 11 (1): 5881. 18 November 2020

Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma.
Helmsauer, K. and Valieva, M.E. and Ali, S. and Chamorro Gonzalez, R. and Schöpflin, R. and Röefzaad, C. and Bei, Y. and Dorado Garcia, H. and Rodriguez-Fos, E. and Puiggròs, M. and Kasack, K. and Haase, K. and Keskeny, C. and Chen, C.Y. and Kuschel, L.P. and Euskirchen, P. and Heinrich, V. and Robson, M.I. and Rosswog, C. and Toedling, J. and Szymansky, A. and Hertwig, F. and Fischer, M. and Torrents, D. and Eggert, A. and Schulte, J.H. and Mundlos, S. and Henssen, A.G. and Koche, R.P.
Nature Communications 11 (1): 5823. 16 November 2020

Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin.
Dyring-Andersen, B. and Løvendorf, M.B. and Coscia, F. and Santos, A. and Møller, L.B.P. and Colaço, A.R. and Niu, L. and Bzorek, M. and Doll, S. and Andersen, J.L. and Clark, R.A. and Skov, L. and Teunissen, M.B.M. and Mann, M.
Nature Communications 11 (1): 5587. 5 November 2020

Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits.
Quach, B.C. and Bray, M.J. and Gaddis, N.C. and Liu, M. and Palviainen, T. and Minica, C.C. and Zellers, S. and Sherva, R. and Aliev, F. and Nothnagel, M. and Young, K.A. and Marks, J.A. and Young, H. and Carnes, M.U. and Guo, Y. and Waldrop, A. and Sey, N..A. and Landi, M.T. and McNeil, D.W. and Drichel, D. and Farrer, L.A. and Markunas, C.A. and Vink, J.M. and Hottenga, J.J. and Iacono, W.G. and Kranzler, H.R. and Saccone, N.L. and Neale, M.C. and Madden, P. and Rietschel, M. and Marazita, M.L. and McGue, M. and Won, H. and Winterer, G. and Grucza, R. and Dick, D.M. and Gelernter, J. and Caporaso, N.E. and Baker, T.B. and Boomsma, D.I. and Kaprio, J. and Hokanson, J.E. and Vrieze, S. and Bierut, L.J. and Johnson, E.O. and Hancock, D.B.
Nature Communications 11 (1): 5562. 3 November 2020

Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Grunwald, S. and Hopf, L.V.M. and Bock-Bierbaum, T. and Lally, C.C.M. and Spahn, C.M.T. and Daumke, O.
Nature Communications 11 (1): 5506. 2 November 2020

YAP and TAZ protect against white adipocyte cell death during obesity.
Wang, L. and Wang, S.P. and Shi, Y. and Li, R. and Günther, S. and Ong, Y.T. and Potente, M. and Yuan, Z. and Liu, E. and Offermanns, S.
Nature Communications 11 (1): 5455. 28 October 2020

Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.
Lutsik, P. and Baude, A. and Mancarella, D. and Öz, S. and Kühn, A. and Toth, R. and Hey, J. and Toprak, U.H. and Lim, J. and Nguyen, V.H. and Jiang, C. and Mayakonda, A. and Hartmann, M. and Rosemann, F. and Breuer, K. and Vonficht, D. and Grünschläger, F. and Lee, S. and Schuhmacher, M.K. and Kusevic, D. and Jauch, A. and Weichenhan, D. and Zustin, J. and Schlesner, M. and Haas, S. and Park, J.H. and Park, Y.J. and Oppermann, U. and Jeltsch, A. and Haller, F. and Fellenberg, J. and Lindroth, A.M. and Plass, C.
Nature Communications 11 (1): 5414. 27 October 2020

The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models.
Klems, A. and van Rijssel, J. and Ramms, A.S. and Wild, R. and Hammer, J. and Merkel, M. and Derenbach, L. and Préau, L. and Hinkel, R. and Suarez-Martinez, I. and Schulte-Merker, S. and Vidal, R. and Sauer, S. and Kivelä, R. and Alitalo, K. and Kupatt, C. and van Buul, J.D. and le Noble, F.
Nature Communications 11 (1): 5319. 21 October 2020

Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis.
Bogdanow, B. and Schmidt, M. and Weisbach, H. and Gruska, I. and Vetter, B. and Imami, K. and Ostermann, E. and Brune, W. and Selbach, M. and Hagemeier, C. and Wiebusch, L.
Nature Communications 11 (1): 4845. 24 September 2020

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Bailey, M.H. and Meyerson, W.U. and Dursi, L.J. and Wang, L.B. and Dong, G. and Liang, W.W. and Weerasinghe, A. and Li, S. and Li, Y. and Kelso, S. and Saksena, G. and Ellrott, K. and Wendl, M.C. and Wheeler, D.A. and Getz, G. and Simpson, J.T. and Gerstein, M.B. and Ding, Li
Nature Communications 11 (1): 4748. 21 September 2020

A machine learning-based chemoproteomic approach to identify drug targets and binding sites in complex proteomes.
Piazza, I. and Beaton, N. and Bruderer, R. and Knobloch, T. and Barbisan, C. and Chandat, L. and Sudau, A. and Siepe, I. and Rinner, O. and de Souza, N. and Picotti, P. and Reiter, L.
Nature Communications 11 (1): 4200. 21 August 2020

Subnanometer-resolution structure determination in situ by hybrid subtomogram averaging - single particle cryo-EM.
Sanchez, R.M. and Zhang, Y. and Chen, W. and Dietrich, L. and Kudryashev, M.
Nature Communications 11 (1): 3709. 24 July 2020

H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients.
Schleich, K. and Kase, J. and Dörr, J.R. and Trescher, S. and Bhattacharya, A. and Yu, Y. and Wailes, E.M. and Fan, D.N.Y. and Lohneis, P. and Milanovic, M. and Lau, A. and Lenze, D. and Hummel, M. and Chapuy, B. and Leser, U. and Reimann, M. and Lee, S. and Schmitt, C.A.
Nature Communications 11 (1): 3651. 20 July 2020

Deep learning for genomics using Janggu.
Kopp, W. and Monti, R. and Tamburrini, A. and Ohler, U. and Akalin, A.
Nature Communications 11 (1): 3488. 13 July 2020

Polymer physics indicates chromatin folding variability across single-cells results from state degeneracy in phase separation.
Conte, M. and Fiorillo, L. and Bianco, S. and Chiariello, A.M. and Esposito, A. and Nicodemi, M.
Nature Communications 11 (1): 3289. 3 July 2020

Deconstructing sarcomeric structure-function relations in titin-BioID knock-in mice.
Rudolph, F. and Fink, C. and Hüttemeister, J. and Kirchner, M. and Radke, M.H. and Lopez Carballo, J. and Wagner, E. and Kohl, T. and Lehnart, S.E. and Mertins, P. and Gotthardt, M.
Nature Communications 11 (1): 3133. 19 June 2020

Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica.
Agasing, A.M. and Wu, Q. and Khatri, B. and Borisow, N. and Ruprecht, K. and Brandt, A.U. and Gawde, S. and Kumar, G. and Quinn, J.L. and Ko, R.M. and Mao-Draayer, Y. and Lessard, C.J. and Paul, F. and Axtell, R.C.
Nature Communications 11 (1): 2856. 5 June 2020

Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing.
Stangl, C. and de Blank, S. and Renkens, I. and Westera, L. and Verbeek, T. and Valle-Inclan, J.E. and Chamorro González, R. and Henssen, A.G. and van Roosmalen, M.J. and Stam, R.W. and Voest, E.E. and Kloosterman, W.P. and van Haaften, G. and Monroe, G.R.
Nature Communications 11 (1): 2861. 5 June 2020

FoxO1-Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth.
Ferdous, A. and Wang, Z.V. and Luo, Y. and Li, D.L. and Luo, X. and Schiattarella, G.G. and Altamirano, F. and May, H.I. and Battiprolu, P.K. and Nguyen, A. and Rothermel, B.A. and Lavandero, S. and Gillette, T.G. and Hill, J.A.
Nature Communications 11 (1): 2551. 21 May 2020

Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Marchetto, A. and Ohmura, S. and Orth, M.F. and Knott, M.M.L. and Colombo, M.V. and Arrigoni, C. and Bardinet, V. and Saucier, D. and Wehweck, F.S. and Li, J. and Stein, S. and Gerke, J.S. and Baldauf, M.C. and Musa, J. and Dallmayer, M. and Romero-Pérez, L. and Hölting, T.L.B. and Amatruda, J.F. and Cossarizza, A. and Henssen, A.G. and Kirchner, T. and Moretti, M. and Cidre-Aranaz, F. and Sannino, G. and Grünewald, T.G.P.
Nature Communications 11 (1): 2423. 15 May 2020

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.
Vinckier, N.K. and Patel, N.A. and Geusz, R.J. and Wang, A. and Wang, J. and Matta, I. and Harrington, A.R. and Wortham, M. and Wetton, N. and Wang, J. and Jhala, U.S. and Rosenfeld, M.G. and Benner, C.W. and Shih, H.P. and Sander, M.
Nature Communications 11 (1): 2082. 29 April 2020

Integrative functional genomics decodes herpes simplex virus 1.
Whisnant, A.W. and Jürges, C.S. and Hennig, T. and Wyler, E. and Prusty, B. and Rutkowski, A.J. and L'hernault, A. and Djakovic, L. and Göbel, M. and Döring, K. and Menegatti, J. and Antrobus, R. and Matheson, N.J. and Künzig, F.W.H. and Mastrobuoni, G. and Bielow, C. and Kempa, S. and Liang, C. and Dandekar, T. and Zimmer, R. and Landthaler, M. and Grässer, F. and Lehner, P.J. and Friedel, C.C. and Erhard, F. and Dölken, L.
Nature Communications 11 (1): 2038. 27 April 2020

Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity.
Seo, J.A. and Kang, M.C. and Yang, W.M. and Hwang, W.M. and Kim, S.S. and Hong, S.H. and Heo, J.I. and Vijyakumar, A. and Pereira de Moura, L. and Uner, A. and Huang, H. and Lee, S.H. and Lima, I.S. and Park, K.S. and Kim, M.S. and Dagon, Y. and Willnow, T.E. and Aroda, V. and Ciaraldi, T.P. and Henry, R.R. and Kim, Y.B.
Nature Communications 11 (1): 2024. 24 April 2020

Propagation of hippocampal ripples to the neocortex by way of a subiculum-retrosplenial pathway.
Nitzan, N. and McKenzie, S. and Beed, P. and English, D.F. and Oldani, S. and Tukker, J.J. and Buzsáki, G. and Schmitz, D.
Nature Communications 11 (1): 1947. 23 April 2020

Ribosome profiling at isoform level reveals evolutionary conserved impacts of differential splicing on the proteome.
Reixachs-Solé, M. and Ruiz-Orera, J. and Albà, M.M. and Eyras, E.
Nature Communications 11 (1): 1768. 14 April 2020

Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes.
Chong, C. and Müller, M. and Pak, H.S. and Harnett, D. and Huber, F. and Grun, D. and Leleu, M. and Auger, A. and Arnaud, M. and Stevenson, B.J. and Michaux, J. and Bilic, I. and Hirsekorn, A. and Calviello, L. and Simó-Riudalbas, L. and Planet, E. and Lubiński, J. and Bryśkiewicz, M. and Wiznerowicz, M. and Xenarios, I. and Zhang, L. and Trono, D. and Harari, A. and Ohler, U. and Coukos, G. and Bassani-Sternberg, M.
Nature Communications 11 (1): 1293. 10 March 2020

Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features.
Ray, J.P. and de Boer, C.G. and Fulco, C.P. and Lareau, C.A. and Kanai, M. and Ulirsch, J.C. and Tewhey, R. and Ludwig, L.S. and Reilly, S.K. and Bergman, D.T. and Engreitz, J.M. and Issner, R. and Finucane, H.K. and Lander, E.S. and Regev, A. and Hacohen, N.
Nature Communications 11 (1): 1237. 6 March 2020

Tracing tumorigenesis in a solid tumor model at single-cell resolution.
Praktiknjo, S.D. and Obermayer, B. and Zhu, Q. and Fang, L. and Liu, H. and Quinn, H. and Stoeckius, M. and Kocks, C. and Birchmeier, W. and Rajewsky, N.
Nature Communications 11 (1): 991. 20 February 2020

Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients.
Fendler, A. and Bauer, D. and Busch, J. and Jung, K. and Wulf-Goldenberg, A. and Kunz, S. and Song, K. and Myszczyszyn, A. and Elezkurtaj, S. and Erguen, B. and Jung, S. and Chen, W. and Birchmeier, W.
Nature Communications 11 (1): 929. 17 February 2020

High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Zhang, Y. and Chen, F. and Fonseca, N.A. and He, Y. and Fujita, M. and Nakagawa, H. and Zhang, Z. and Brazma, A. and Creighton, C.J.
Nature Communications 11 (1): 736. 5 February 2020

Human and mouse essentiality screens as a resource for disease gene discovery.
Cacheiro, P. and Muñoz-Fuentes, V. and Murray, S.A. and Dickinson, M.E. and Bucan, M. and Nutter, L.M.J. and Peterson, K.A. and Haselimashhadi, H. and Flenniken, A.M. and Morgan, H. and Westerberg, H. and Konopka, T. and Hsu, C.W. and Christiansen, A. and Lanza, D.G. and Beaudet, A.L. and Heaney, J.D. and Fuchs, H. and Gailus-Durner, V. and Sorg, T. and Prochazka, J. and Novosadova, V. and Lelliott, C.J. and Wardle-Jones, H. and Wells, S. and Teboul, L. and Cater, H. and Stewart, M. and Hough, T. and Wurst, W. and Sedlacek, R. and Adams, D.J. and Seavitt, J.R. and Tocchini-Valentini, G. and Mammano, F. and Braun, R.E. and McKerlie, C. and Herault, Y. and de Angelis, M.H. and Mallon, A.M. and Lloyd, K.C.K. and Brown, S.D.M. and Parkinson, H. and Meehan, T.F. and Smedley, D.
Nature Communications 11 (1): 655. 31 January 2020

Rapid and deep-scale ubiquitylation profiling for biology and translational research.
Udeshi, N.D. and Mani, D.C. and Satpathy, S. and Fereshetian, S. and Gasser, J.A. and Svinkina, T. and Olive, M.E. and Ebert, B.L. and Mertins, P. and Carr, S.A.
Nature Communications 11 (1): 359. 17 January 2020

Cold-induced urticarial autoinflammatory syndrome related to factor XII activation.
Scheffel, J. and Mahnke, N.A. and Hofman, Z.L.M. and Maat, S.d. and Wu, J. and Bonnekoh, H. and Pengelly, R.J. and Ennis, S. and Holloway, J.W. and Kirchner, M. and Mertins, P. and Church, M.K. and Maurer, M. and Maas, C. and Krause, K.
Nature Communications 11 (1): 179. 10 January 2020

Single-cell analysis based dissection of clonality in myelofibrosis.
Mylonas, E. and Yoshida, K. and Frick, M. and Hoyer, K. and Christen, F. and Kaeda, J. and Obenaus, M. and Noerenberg, D. and Hennch, C. and Chan, W. and Ochi, Y. and Shiraishi, Y. and Shiozawa, Y. and Zenz, T. and Oakes, C.C. and Sawitzki, B. and Schwarz, M. and Bullinger, L. and le Coutre, P. and Rose-Zerilli, M.J.J. and Ogawa, S. and Damm, F.
Nature Communications 11 (1): 73. 7 January 2020

Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage.
Goulielmaki, E. and Ioannidou, A. and Tsekrekou, M. and Stratigi, K. and Poutakidou, I.K. and Gkirtzimanaki, K. and Aivaliotis, M. and Evangelou, K. and Topalis, P. and Altmüller, J. and Gorgoulis, V.G. and Chatzinikolaou, G. and Garinis, G.A.
Nature Communications 11 (1): 42. 2 January 2020

CD8(+) T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.
Gross, C.C. and Meyer, C. and Bhatia, U. and Yshii, L. and Kleffner, I. and Bauer, J. and Tröscher, A.R. and Schulte-Mecklenbeck, A. and Herich, S. and Schneider-Hohendorf, T. and Plate, H. and Kuhlmann, T. and Schwaninger, M. and Brück, W. and Pawlitzki, M. and Laplaud, D.A. and Loussouarn, D. and Parratt, J. and Barnett, M. and Buckland, M.E. and Hardy, T.A. and Reddel, S.W. and Ringelstein, M. and Dörr, J. and Wildemann, B. and Kraemer, M. and Lassmann, H. and Höftberger, R. and Beltrán, E. and Dornmair, K. and Schwab, N. and Klotz, L. and Meuth, S.G. and Martin-Blondel, G. and Wiendl, H. and Liblau, R.
Nature Communications 10 (1): 5779. 18 December 2019

Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.
Marg, A. and Escobar Fernandez, H. and Karaiskos, N. and Grunwald, S.A. and Metzler, E. and Kieshauer, J. and Sauer, S. and Pasemann, D. and Malfatti, E. and Mompoint, D. and Quijano-Roy, S. and Boltengagen, A. and Schneider, J. and Schülke, M. and Kunz, S. and Carlier, R. and Birchmeier, C. and Amthor, H. and Spuler, A. and Kocks, C. and Rajewsky, N. and Spuler, S.
Nature Communications 10 (1): 5776. 18 December 2019

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B. and Wang, X. and Eichelbaum, K. and Sadewasser, A. and Husic, I. and Paki, K. and Budt, M. and Hergeselle, M. and Vetter, B. and Hou, J. and Chen, W. and Wiebusch, L. and Meyer, I.M. and Wolff, T. and Selbach, M.
Nature Communications 10 (1): 5518. 4 December 2019

Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation.
Schewe, J. and Seidel, E. and Forslund, S. and Marko, L. and Peters, J. and Muller, D.N. and Fahlke, C. and Stölting, G. and Scholl, U.
Nature Communications 10 (1): 5155. 14 November 2019

Full-length transcriptome reconstruction reveals a large diversity of RNA and protein isoforms in rat hippocampus.
Wang, X. and You, X. and Langer, J.D. and Hou, J. and Rupprecht, F. and Vlatkovic, I. and Quedenau, C. and Tushev, G. and Epstein, I. and Schaefke, B. and Sun, W. and Fang, L. and Li, G. and Hu, Y. and Schuman, E.M. and Chen, W.
Nature Communications 10 (1): 5009. 1 November 2019

Unstable TTTTA/TTTCA expansions in MARCH6 are associated with Familial Adult Myoclonic Epilepsy type 3.
Florian, R.T. and Kraft, F. and Leitão, E. and Kaya, S. and Klebe, S. and Magnin, E. and van Rootselaar, A.F. and Buratti, J. and Kühnel, T. and Schröder, C. and Giesselmann, S. and Tschernoster, N. and Altmüller, J. and Lamiral, A. and Keren, B. and Nava, C. and Bouteiller, D. and Forlani, S. and Jornea, L. and Kubica, R. and Ye, T. and Plassard, D. and Jost, B. and Meyer, V. and Deleuze, J.F. and Delpu, Y. and Avarello, M.D.M. and Vijfhuizen, L.S. and Rudolf, G. and Hirsch, E. and Kroes, T. and Reif, P.S. and Rosenow, F. and Ganos, C. and Vidailhet, M. and Thivard, L. and Mathieu, A. and Bourgeron, T. and Kurth, I. and Rafehi, H. and Steenpass, L. and Horsthemke, B. and LeGuern, E. and Klein, K.M. and Labauge, P. and Bennett, M.F. and Bahlo, M. and Gecz, J. and Corbett, M.A. and Tijssen, M.A.J and van den Maagdenberg, A.M.J.M. and Depienne, C.
Nature Communications 10 (1): 4919. 29 October 2019

Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program.
Wyler, E. and Franke, V. and Menegatti, J. and Kocks, C. and Boltengagen, A. and Praktiknjo, S. and Walch-Rückheim, B. and Bosse, J. and Rajewsky, N. and Grässer, F. and Akalin, A. and Landthaler, M.
Nature Communications 10 (1): 4878. 25 October 2019

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.
Wong, J.B. and Hewitt, S.L. and Heltemes-Harris, L.M. and Mandal, M. and Johnson, K. and Rajewsky, K. and Koralov, S.B. and Clark, M.R. and Farrar, M.A. and Skok, J.A.
Nature Communications 10 (1): 4768. 18 October 2019

Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism.
Göppner, C. and Orozco, I.J. and Hoegg-Beiler, M.B. and Soria, A.H. and Hübner, C.A. and Fernandes-Rosa, F.L. and Boulkroun, S. and Zennaro, M.C. and Jentsch, T.J.
Nature Communications 10 (1): 4678. 15 October 2019

R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.
Harnack, C. and Berger, H. and Antanaviciute, A. and Vidal, R. and Sauer, S. and Simmons, A. and Meyer, T.F. and Sigal, M.
Nature Communications 10 (1): 4368. 25 September 2019

Identification of proteins and miRNAs that specifically bind an mRNA in vivo.
Theil, K. and Imami, K. and Rajewsky, N.
Nature Communications 10 (1): 4205. 16 September 2019

Maximizing binary interactome mapping with a minimal number of assays.
Choi, S.G. and Olivet, J. and Cassonnet, P. and Vidalain, P.O. and Luck, K. and Lambourne, L. and Spirohn, K. and Lemmens, I. and Dos Santos, M. and Demeret, C. and Jones, L. and Rangarajan, S. and Bian, W. and Coutant, E.P. and Janin, Y.L. and van der Werf, S. and Trepte, P. and Wanker, E.E. and De Las Rivas, J. and Tavernier, J. and Twizere, J.C. and Hao, T. and Hill, D.E. and Vidal, M. and Calderwood, M.A. and Jacob, Y.
Nature Communications 10 (1): 3907. 29 August 2019

Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids.
Alcala, N. and Leblay, N. and Gabriel, A.A.G. and Mangiante, L. and Hervas, D. and Giffon, T. and Sertier, A.S. and Ferrari, A. and Derks, J. and Ghantous, A. and Delhomme, T.M. and Chabrier, A. and Cuenin, C. and Abedi-Ardekani, B. and Boland, A. and Olaso, R. and Meyer, V. and Altmuller, J. and Le Calvez-Kelm, F. and Durand, G. and Voegele, C. and Boyault, S. and Moonen, L. and Lemaitre, N. and Lorimier, P. and Toffart, A.C. and Soltermann, A. and Clement, J.H. and Saenger, J. and Field, J.K. and Brevet, M. and Blanc-Fournier, C. and Galateau-Salle, F. and Le Stang, N. and Russell, P.A. and Wright, G. and Sozzi, G. and Pastorino, U. and Lacomme, S. and Vignaud, J.M. and Hofman, V. and Hofman, P. and Brustugun, O.T. and Lund-Iversen, M. and Thomas de Montpreville, V. and Muscarella, L.A. and Graziano, P. and Popper, H. and Stojsic, J. and Deleuze, J.F. and Herceg, Z. and Viari, A. and Nuernberg, P. and Pelosi, G. and Dingemans, A.M.C. and Milione, M. and Roz, L. and Brcic, L. and Volante, M. and Papotti, M.G. and Caux, C. and Sandoval, J. and Hernandez-Vargas, H. and Brambilla, E. and Speel, E.J.M. and Girard, N. and Lantuejoul, S. and McKay, J.D. and Foll, M. and Fernandez-Cuesta, L.
Nature Communications 10 (1): 3407. 20 August 2019

WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.
Chen, H. and Moreno-Moral, A. and Pesce, F. and Devapragash, N. and Mancini, M. and Heng, E.L. and Rotival, M. and Srivastava, P.K. and Harmston, N. and Shkura, K. and Rackham, O.J.L. and Yu, W.P. and Sun, X.M. and Tee, N.G.Z. and Tan, E.L.S. and Barton, P.J.R. and Felkin, L.E. and Lara-Pezzi, E. and Angelini, G. and Beltrami, C. and Pravenec, M. and Schafer, A. and Bottolo, L. and Hubner, N. and Emanueli, C. and Cook, S.A. and Petretto, E.
Nature Communications 10 (1): 3616. 9 August 2019

Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy.
Bhaskara, R.M. and Grumati, P. and Garcia-Pardo, J. and Kalayil, S. and Covarrubias-Pinto, A. and Chen, W. and Kudryashev, M. and Dikic, I. and Hummer, G.
Nature Communications 10 (1): 2370. 30 May 2019

Blimp1(+) cells generate functional mouse sebaceous gland organoids in vitro.
Feldman, A. and Mukha, D. and Maor, I.I. and Sedov, E. and Koren, E. and Yosefzon, Y. and Shlomi, T. and Fuchs, Y.
Nature Communications 10 (1): 2348. 28 May 2019

Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk.
Greenwald, W.W. and Chiou, J. and Yan, J. and Qiu, Y. and Dai, N. and Wang, A. and Nariai, N. and Aylward, A. and Han, J.Y. and Kadakia, N. and Regue, L. and Okino, M.L. and Drees, F. and Kramer, D. and Vinckier, N. and Minichiello, L. and Gorkin, D. and Avruch, J. and Frazer, K.A. and Sander, M. and Ren, B. and Gaulton, K.J.
Nature Communications 10 (1): 2078. 7 May 2019

Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation.
Cocciardi, S. and Dolnik, A. and Kapp-Schwoerer, S. and Rücker, F.G. and Lux, S. and Blätte, T.J. and Skambraks, S. and Krönke, J. and Heidel, F.H. and Schnöder, T.M. and Corbacioglu, A. and Gaidzik, V.I. and Paschka, P. and Teleanu, V. and Göhring, G. and Thol, F. and Heuser, M. and Ganser, A. and Weber, D. and Sträng, E. and Kestler, H.A. and Döhner, H. and Bullinger, L. and Döhner, K.
Nature Communications 10 (1): 2031. 2 May 2019

Multi-platform discovery of haplotype-resolved structural variation in human genomes.
Chaisson, M.J.P. and Sanders, A.D. and Zhao, X. and Malhotra, A. and Porubsky, D. and Rausch, T. and Gardner, E.J. and Rodriguez, O.L. and Guo, L. and Collins, R.L. and Fan, X. and Wen, J. and Handsaker, R.E. and Fairley, S. and Kronenberg, Z.N. and Kong, X. and Hormozdiari, F. and Lee, D. and Wenger, A.M. and Hastie, A.R. and Antaki, D. and Anantharaman, T. and Audano, P.A. and Brand, H. and Cantsilieris, S. and Cao, H. and Cerveira, E. and Chen, C. and Chen, X. and Chin, C.S. and Chong, Z. and Chuang, N.T. and Lambert, C.C. and Church, D.M. and Clarke, L. and Farrell, A. and Flores, J. and Galeev, T. and Gorkin, D.U. and Gujral, M. and Guryev, V. and Heaton, W.H. and Korlach, J. and Kumar, S. and Kwon, J.Y. and Lam, E.T. and Lee, J.E. and Lee, J. and Lee, W.P. and Lee, S.P. and Li, S. and Marks, P. and Viaud-Martinez, K. and Meiers, S. and Munson, K.M. and Navarro, F.C.P. and Nelson, B.J. and Nodzak, C. and Noor, A. and Kyriazopoulou-Panagiotopoulou, S. and Pang, A.W.C. and Qiu, Y. and Rosanio, G. and Ryan, M. and Stütz, A. and Spierings, D.C.J. and Ward, A. and Welch, A.E. and Xiao, M. and Xu, W. and Zhang, C. and Zhu, Q. and Zheng-Bradley, X. and Lowy, E. and Yakneen, S. and McCarroll, S. and Jun, G. and Ding, L. and Koh, C.L. and Ren, B. and Flicek, P. and Chen, K. and Gerstein, M.B. and Kwok, P.Y. and Lansdorp, P.M. and Marth, G.T. and Sebat, J. and Shi, X. and Bashir, A. and Ye, K. and Devine, S.E. and Talkowski, M.E. and Mills, R.E. and Marschall, T. and Korbel, J.O. and Eichler, E.E. and Lee, C.
Nature Communications 10 (1): 1784. 16 April 2019

Global identification of functional microRNA-mRNA interactions in Drosophila.
Wessels, H.H. and Lebedeva, S. and Hirsekorn, A. and Wurmus, R. and Akalin, A. and Mukherjee, N. and Ohler, U.
Nature Communications 10 (1): 1626. 9 April 2019

Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
Niogret, C. and Miah, S.M.S. and Rota, G. and Fonta, N.P. and Wang, H. and Held, W. and Birchmeier, W. and Sexl, V. and Yang, W. and Vivier, E. and Ho, P.C. and Brossay, L. and Guarda, G.
Nature Communications 10 (1): 1444. 29 March 2019

Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly.
Lahrouchi, N. and George, A. and Ratbi, I. and Schneider, R. and Elalaoui, S.C. and Moosa, S. and Bharti, S. and Sharma, R. and Abu-Asab, M. and Onojafe, F. and Adadi, N. and Lodder, E.M. and Laarabi, F.Z. and Lamsyah, Y. and Elorch, H. and Chebbar, I. and Postma, A.V. and Lougaris, V. and Plebani, A. and Altmueller, J. and Kyrieleis, H. and Meiner, V. and McNeill, H. and Bharti, K. and Lyonnet, S. and Wollnik, B. and Henrion-Caude, A. and Berraho, A. and Hildebrandt, F. and Bezzina, C.R. and Brooks, B.P. and Sefiani, A.
Nature Communications 10 (1): 1180. 12 March 2019

Microbial abundance, activity and population genomic profiling with mOTUs2.
Milanese, A. and Mende, D.R. and Paoli, L. and Salazar, G. and Ruscheweyh, H.J. and Cuenca, M. and Hingamp, P. and Alves, R. and Costea, P.I. and Coelho, L.P. and Schmidt, T.S.B. and Almeida, A. and Mitchell, A.L. and Finn, R.D. and Huerta-Cepas, J. and Bork, P. and Zeller, G. and Sunagawa, S.
Nature Communications 10 (1): 1014. 4 March 2019

Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
Urdaneta, E.C. and Vieira-Vieira, C.H. and Hick, T. and Wessels, H.H. and Figini, D. and Moschall, R. and Medenbach, J. and Ohler, U. and Granneman, S. and Selbach, M. and Beckmann, B.M.
Nature Communications 10 (1): 990. 1 March 2019

E47 modulates hepatic glucocorticoid action.
Hemmer, M.C. and Wierer, M. and Schachtrup, K. and Downes, M. and Hübner, N. and Evans, R.M. and Uhlenhaut, N.H.
Nature Communications 10 (1): 306. 18 January 2019

Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Starossom, S.C. and Campo Garcia, J. and Woelfle, T. and Romero-Suarez, S. and Olah, M. and Watanabe, F. and Cao, L. and Yeste, A. and Tukker, J.J. and Quintana, F.J. and Imitola, J. and Witzel, F. and Schmitz, D. and Morkel, M. and Paul, F. and Infante-Duarte, C. and Khoury, S.J.
Nature Communications 10 (1): 217. 15 January 2019

A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding.
Hernáez, B. and Alonso-Lobo, J.M. and Montanuy, I. and Fischer, C. and Sauer, S. and Sigal, L. and Sevilla, N. and Alcamí, A.
Nature Communications 9 (1): 5440. 21 December 2018

aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability.
Riddell, M. and Nakayama, A. and Hikita, T. and Mirzapourshafiyi, F. and Kawamura, T. and Pasha, A. and Li, M. and Masuzawa, M. and Looso, M. and Steinbacher, T. and Ebnet, K. and Potente, M. and Hirose, T. and Ohno, S. and Fleming, I. and Gattenlöhner, S. and Aung, P.P. and Phung, T. and Yamasaki, O. and Yanagi, T. and Umemura, H. and Nakayama, M.
Nature Communications 9 (1): 5357. 17 December 2018

Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis.
Campa, C.C. and Silva, R.L. and Margaria, J.P. and Pirali, T. and Mattos, M.S. and Kraemer, L.R. and Reis, D.C. and Grosa, G. and Copperi, F. and Dalmarco, E.M. and Lima-Júnior, R.C.P. and Aprile, S. and Sala, V. and Dal Bello, F. and Prado, D.S. and Alves-Filho, J.C. and Medana, C. and Cassali, G.D. and Tron, G.C. and Teixeira, M.M. and Ciraolo, E. and Russo, R.C. and Hirsch, E.
Nature Communications 9 (1): 5232. 12 December 2018

GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis.
Cabral-Marques, O. and Marques, A. and Giil, L.M. and De Vito, R. and Rademacher, J. and Günther, J. and Lange, T. and Humrich, J.Y. and Klapa, S. and Schinke, S. and Schimke, L.F. and Marschner, G. and Pitann, S. and Adler, S. and Dechend, R. and Müller, D.N. and Braicu, I. and Sehouli, J. and Schulze-Forster, K. and Trippel, T. and Scheibenbogen, C. and Staff, A. and Mertens, P.R. and Löbel, M. and Mastroianni, J. and Plattfaut, C. and Gieseler, F. and Dragun, D. and Engelhardt, B.E. and Fernandez-Cabezudo, M.J. and Ochs, H.D. and Al-Ramadi, B.K. and Lamprecht, P. and Mueller, A. and Heidecke, H. and Riemekasten, G.
Nature Communications 9 (1): 5224. 6 December 2018

Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors.
Escot, S. and Willnow, D. and Naumann, H. and Di Francescantonio, S. and Spagnoli, F.M.
Nature Communications 9 (1): 5082. 30 November 2018

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets.
Decaesteker, B. and Denecker, G. and Van Neste, C. and Dolman, E.M. and Van Loocke, W. and Gartlgruber, M. and Nunes, C. and De Vloed, F. and Depuydt, P. and Verboom, K. and Rombaut, D. and Loontiens, S. and De Wyn, J. and Kholosy, W.M. and Koopmans, B. and Essing, A.H.W. and Herrmann, C. and Dreidax, D. and Durinck, K. and Deforce, D. and van Nieuwerburgh, F. and Henssen, A. and Versteeg, R. and Boeva, V. and Schleiermacher, G. and van Nes, J. and Mestdagh, P. and Vanhauwaert, S. and Schulte, J.H. and Westermann, F. and Molenaar, J.J. and De Preter, K. and Speleman, F.
Nature Communications 9 (1): 4866. 19 November 2018

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.
Angulo-Urarte, A. and Casado, P. and Castillo, S.D. and Kobialka, P. and Kotini, M.P. and Figueiredo, A.M. and Castel, P. and Rajeeve, V. and Milà-Guasch, M. and Millan, J. and Wiesner, C. and Serra, H. and Muixi, L. and Casanovas, O. and Viñals, F. and Affolter, M. and Gerhardt, H. and Huveneers, S. and Belting, H.G. and Cutillas, P.R. and Graupera, M.
Nature Communications 9 (1): 4826. 16 November 2018

Potassium channel-based optogenetic silencing.
Bernal Sierra, Y.A. and Rost, B.R. and Pofahl, M. and Fernandes, A.M. and Kopton, R.A. and Moser, S. and Holtkamp, D. and Masala, N. and Beed, P. and Tukker, J.J. and Oldani, S. and Bönigk, W. and Kohl, P. and Baier, H. and Schneider-Warme, F. and Hegemann, P. and Beck, H. and Seifert, R. and Schmitz, D.
Nature Communications 9 (1): 4611. 5 November 2018

ARTS mediates apoptosis and regeneration of the intestinal stem cell niche.
Koren, E. and Yosefzon, Y. and Ankawa, R. and Soteriou, D. and Jacob, A. and Nevelsky, A. and Ben-Yosef, R. and Bar-Sela, G. and Fuchs, Y.
Nature Communications 9 (1): 4582. 2 November 2018

Determinants of promoter and enhancer transcription directionality in metazoans.
Ibrahim, M.M. and Karabacak, A. and Glahs, A. and Kolundzic, E. and Hirsekorn, A. and Carda, A. and Tursun, B. and Zinzen, R.P. and Lacadie, S.A. and Ohler, U.
Nature Communications 9 (1): 4472. 26 October 2018

Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells.
Stone, O.A. and El-Brolosy, M. and Wilhelm, K. and Liu, X. and Romão, A.M. and Grillo, E. and Lai, J.K.H. and Günther, S. and Jeratsch, S. and Kuenne, C. and Lee, I.C. and Braun, T. and Santoro, M.M. and Locasale, J.W. and Potente, M. and Stainier, D.Y.R.
Nature Communications 9 (1): 4077. 9 October 2018

Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy.
Iannotti, F.A. and Pagano, E. and Guardiola, O. and Adinolfi, S. and Saccone, V. and Consalvi, S. and Piscitelli, F. and Gazzerro, E. and Busetto, G. and Carrella, D. and Capasso, R. and Puri, P.L. and Minchiotti, G. and Di Marzo, V.
Nature Communications 9 (1): 3950. 27 September 2018

Structural basis for membrane tethering by a bacterial dynamin-like pair.
Liu, J. and Noel, J.K. and Low, H.H.
Nature Communications 9 (1): 3345. 21 August 2018

The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Zehender, A. and Huang, J. and Györfi, A.H. and Matei, A.E. and Trinh-Minh, T. and Xu, X. and Li, Y.N. and Chen, C.W. and Lin, J. and Dees, C. and Beyer, C. and Gelse, K. and Zhang, Z.Y. and Bergmann, C. and Ramming, A. and Birchmeier, W. and Distler, O. and Schett, G. and Distler, J.H.W.
Nature Communications 9 (1): 3259. 14 August 2018

Role of VTA dopamine neurons and neuroligin 3 in sociability traits related to nonfamiliar conspecific interaction.
Bariselli, S. and Hörnberg, H. and Prévost-Solié, C. and Musardo, S. and Hatstatt-Burklé, L. and Scheiffele, P. and Bellone, C.
Nature Communications 9 (1): 3173. 9 August 2018

Embryos and embryonic stem cells from the white rhinoceros.
Hildebrandt, T.B. and Hermes, R. and Colleoni, S. and Diecke, S. and Holtze, S. and Renfree, M.B. and Stejskal, J. and Hayashi, K. and Drukker, M. and Loi, P. and Göritz, F. and Lazzari, G. and Galli, C.
Nature Communications 9 (1): 2589. 4 July 2018

Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity.
Merks, A.M. and Swinarski, M. and Meyer, A.M. and Müller, N.V. and Özcan, I. and Donat, S. and Burger, A. and Gilbert, S. and Mosimann, C. and Abdelilah-Seyfried, S. and Panáková, D.
Nature Communications 9 (1): 2161. 4 June 2018

Postnatal DNA demethylation and its role in tissue maturation.
Reizel, Y. and Sabag, O. and Skversky, Y. and Spiro, A. and Steinberg, B. and Bernstein, D. and Wang, A. and Kieckhaefer, J. and Li, C. and Pikarsky, E. and Levin-Klein, R. and Goren, A. and Rajewsky, K. and Kaestner, K.H. and Cedar, H.
Nature Communications 9 (1): 2040. 23 May 2018

Continuous addition of progenitors forms the cardiac ventricle in zebrafish.
Felker, A. and Prummel, K.D. and Merks, A.M. and Mickoleit, M. and Brombacher, E.C. and Huisken, J. and Panáková, D. and Mosimann, C.
Nature Communications 9 (1): 2001. 21 May 2018

LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion.
Stuhlmann, T. and Planells-Cases, R. and Jentsch, T.J.
Nature Communications 9 (1): 1974. 17 May 2018

Linear mitochondrial DNA is rapidly degraded by components of the replication machinery.
Peeva, V. and Blei, D. and Trombly, G. and Corsi, S. and Szukszto, M.J. and Rebelo-Guiomar, P. and Gammage, P.A. and Kudin, A.P. and Becker, C. and Altmüller, J. and Minczuk, M. and Zsurka, G. and Kunz, W.S.
Nature Communications 9 (1): 1727. 30 April 2018

Single synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo.
Jouhanneau, J.S. and Kremkow, J. and Poulet, J.F.A.
Nature Communications 9 (1): 1540. 18 April 2018

Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid.
Birol, M. and Kumar, S. and Rhoades, E. and Miranker, A.D.
Nature Communications 9 (1): 1312. 3 April 2018

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.
Yang, J.Y. and Deng, X.Y. and Li, Y.S. and Ma, X.C. and Feng, J.X. and Yu, B. and Chen, Y. and Luo, Y.L. and Wang, X. and Chen, M.L. and Fang, Z.X. and Zheng, F.X. and Li, Y.P. and Zhong, Q. and Kang, T.B. and Song, L.B. and Xu, R.H. and Zeng, M.S. and Chen, W. and Zhang, H. and Xie, W. and Gao, S.
Nature Communications 9 (1): 1165. 21 March 2018

Voltage gating of mechanosensitive PIEZO channels.
Moroni, M. and Servin-Vences, M.R. and Fleischer, R. and Sánchez-Carranza, O. and Lewin, G.R.
Nature Communications 9 (1): 1096. 15 March 2018

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors.
George, J. and Walter, V. and Peifer, M. and Alexandrov, L.B. and Seidel, D. and Leenders, F. and Maas, L. and Müller, C. and Dahmen, I. and Delhomme, T.M. and Ardin, M. and Leblay, N. and Byrnes, G. and Sun, R. and De Reynies, A. and McLeer-Florin, A. and Bosco, G. and Malchers, F. and Menon, R. and Altmüller, J. and Becker, C. and Nürnberg, P. and Achter, V. and Lang, U. and Schneider, P.M. and Bogus, M. and Soloway, M.G. and Wilkerson, M.D. and Cun, Y. and McKay, J.D. and Moro-Sibilot, D. and Brambilla, C.G. and Lantuejoul, S. and Lemaitre, N. and Soltermann, A. and Weder, W. and Tischler, V. and Brustugun, O.T. and Lund-Iversen, M. and Helland, Å. and Solberg, S. and Ansén, S. and Wright, G. and Solomon, B. and Roz, L. and Pastorino, U. and Petersen, I. and Clement, J.H. and Sänger, J. and Wolf, J. and Vingron, M. and Zander, T. and Perner, S. and Travis, W.D. and Haas, S.A. and Olivier, M. and Foll, M. and Büttner, R. and Hayes, D.N. and Brambilla, E. and Fernandez-Cuesta, L. and Thomas, R.K.
Nature Communications 9 (1): 1048. 13 March 2018

Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia.
Herling, C.D. and Abedpour, N. and Weiss, J. and Schmitt, A. and Jachimowicz, R.D. and Merkel, O. and Cartolano, M. and Oberbeck, S. and Mayer, P. and Berg, V. and Thomalla, D. and Kutsch, N. and Stiefelhagen, M. and Cramer, P. and Wendtner, C.M. and Persigehl, T. and Saleh, A. and Altmüller, J. and Nürnberg, P. and Pallasch, C. and Achter, V. and Lang, U. and Eichhorst, B. and Castiglione, R. and Schäfer, S.C. and Büttner, R. and Kreuzer, K.A. and Reinhardt, H.C. and Hallek, M. and Frenzel, L.P. and Peifer, M.
Nature Communications 9 (1): 727. 20 February 2018

Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL.
Schrader, A. and Crispatzu, G. and Oberbeck, S. and Mayer, P. and Pützer, S. and von Jan, J. and Vasyutina, E. and Warner, K. and Weit, N. and Pflug, N. and Braun, T. and Andersson, E.I. and Yadav, B. and Riabinska, A. and Maurer, B. and Ventura Ferreira, M.S. and Beier, F. and Altmüller, J. and Lanasa, M. and Herling, C.D. and Haferlach, T. and Stilgenbauer, S. and Hopfinger, G. and Peifer, M. and Brümmendorf, T.H. and Nürnberg, P. and Elenitoba-Johnson, K.S.J. and Zha, S. and Hallek, M. and Moriggl, R. and Reinhardt, H.C. and Stern, M.H. and Mustjoki, S. and Newrzela, S. and Frommolt, P. and Herling, M.
Nature Communications 9 (1): 697. 15 February 2018

A global ocean atlas of eukaryotic genes.
Carradec, Q. and Pelletier, E. and Da Silva, C. and Alberti, A. and Seeleuthner, Y. and Blanc-Mathieu, R. and Lima-Mendez, G. and Rocha, F. and Tirichine, L. and Labadie, K. and Kirilovsky, A. and Bertrand, A. and Engelen, S. and Madoui, M.A. and Méheust, R. and Poulain, J. and Romac, S. and Richter, D.J. and Yoshikawa, G. and Dimier, C. and Kandels-Lewis, S. and Picheral, M. and Searson, S. and Jaillon, O. and Aury, J.M. and Karsenti, E. and Sullivan, M.B. and Sunagawa, S. and Bork, P. and Not, F. and Hingamp, P. and Raes, J. and Guidi, L. and Ogata, H. and De Vargas, C. and Iudicone, D. and Bowler, C. and Wincker, P.
Nature Communications 9 (1): 373. 25 January 2018

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
Rozman, J. and Rathkolb, B. and Oestereicher, M.A. and Schütt, C. and Ravindranath, A.C. and Leuchtenberger, S. and Sharma, S. and Kistler, M. and Willershäuser, M. and Brommage, R. and Meehan, T.F. and Mason, J. and Haselimashhadi, H. and Hough, T. and Mallon, A.M. and Wells, S. and Santos, L. and Lelliott, C.J. and White, J.K. and Sorg, T. and Champy, M.F. and Bower, L.R. and Reynolds, C. L. and Flenniken, A.M. and Murray, St.A. and Nutter, L.M.J. and Svenson, K.L. and West, D. and Tocchini-Valentini, G.P. and Beaudet, A.L. and Bosch, F. and Braun, R.B. and Dobbie, M.S. and Gao, X. and Herault, Y. and Moshiri, A. and Moore, B.A. and Kent Lloyd, K.C. and McKerlie, C. and Masuya, H. and Tanaka, N. and Flicek, P. and Parkinson, H.E. and Sedlacek, R. and Seong, J.K. and Wang, C.K.L. and Moore, M. and Brown, S.D. and Tschöp, M.H. and Wurst, W. and Klingenspor, M. and Wolf, E. and Beckers, J. and Machicao, F. and Peter, A. and Staiger, H. and Häring, H.U. and Grallert, H. and Campillos, M. and Maier, H. and Fuchs, H. and Gailus-Durner, V. and Werner, T. and Hrabe de Angelis, M.
Nature Communications 9 (1): 288. 18 January 2018

Perturbation-response genes reveal signaling footprints in cancer gene expression.
Schubert, M. and Klinger, B. and Klünemann, M. and Sieber, A. and Uhlitz, F. and Sauer, S. and Garnett, M.J. and Blüthgen, N. and Saez-Rodriguez, J.
Nature Communications 9 (1): 20. 2 January 2018

Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1.
Pose-Utrilla, J. and García-Guerra, L. and Del Puerto, A. and Martin, A. and Jurado-Arjona, J. and De León-Reyes, N.S. and Gamir-Morralla, A. and Sebastián-Serrano, A. and García-Gallo, M. and Kremer, L. and Fielitz, J. and Ireson, C. and Pérez-Álvarez, M.J. and Ferrer, I. and Hernández, F. and Ávila, J. and Lasa, M. and Campanero, M.R. and Iglesias, T.
Nature Communications 8 (1): 2275. 22 December 2017

Evolutionary action and structural basis of the allosteric switch controlling β(2)AR functional selectivity.
Schönegge, A.M. and Gallion, J. and Picard, L.P. and Wilkins, A.D. and Le Gouill, C. and Audet, M. and Stallaert, W. and Lohse, M.J. and Kimmel, M. and Lichtarge, O. and Bouvier, M.
Nature Communications 8 (1): 2169. 18 December 2017

Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling.
Sassi, Y. and Avramopoulos, P. and Ramanujam, D. and Grüter, L. and Werfel, S. and Giosele, S. and Brunner, A.D. and Esfandyari, D. and Papadopoulou, A.S and De Strooper, B. and Hübner, N. and Kumarswamy, R. and Thum, T. and Yin, X. and Mayr, M. and Laggerbauer, B. and Engelhardt, S.
Nature Communications 8 (1): 1614. 20 November 2017

Transient cardiomyocyte fusion regulates cardiac development in zebrafish.
Sawamiphak, S. and Kontarakis, Z. and Filosa, A. and Reischauer, S. and Stainier, D.Y.R.
Nature Communications 8 (1): 1525. 15 November 2017

Dense and accurate whole-chromosome haplotyping of individual genomes.
Porubsky, D. and Garg, S. and Sanders, A.D. and Korbel, J.O. and Guryev, V. and Lansdorp, P.M. and Marschall, T.
Nature Communications 8 (1): 1293. 3 November 2017

Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.
Marenholz, I. and Grosche, S. and Kalb, B. and Rüschendorf, F. and Blümchen, K. and Schlags, R. and Harandi, N. and Price, M. and Hansen, G. and Seidenberg, J. and Röblitz, H. and Yürek, S. and Tschirner, S. and Hong, X. and Wang, X. and Homuth, G. and Schmidt, C.O. and Nöthen, M.M. and Hübner, N. and Niggemann, B. and Beyer, K. and Lee, Y.A.
Nature Communications 8 (1): 1056. 20 October 2017

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.
Bowl, M.R. and Simon, M.M. and Ingham, N.J. and Greenaway, S. and Santos, L. and Cater, H. and Taylor, S. and Mason, J. and Kurbatova, N. and Pearson, S. and Bower, L.R. and Clary, D.A. and Meziane, H. and Reilly, P. and Minowa, O. and Kelsey, L. and Tocchini-Valentini, G.P. and Gao, X. and Bradley, A. and Skarnes, W.C. and Moore, M. and Beaudet, A.L. and Justice, M.J. and Seavitt, J. and Dickinson, M.E. and Wurst, W. and Hrabe de Angelis, M. and Herault, Y. and Wakana, S. and Nutter, L.M.J. and Flenniken, A.M. and McKerlie, C. and Murray, S.A. and Svenson, K.L. and Braun, R.E. and West, D.B. and Lloyd, K.C.K. and Adams, D.J. and White, J. and Karp, N. and Flicek, P. and Smedley, D. and Meehan, T.F. and Parkinson, H.E. and Teboul, L.M. and Wells, S. and Steel, K.P. and Mallon, A.M. and Brown, S.D.M.
Nature Communications 8 (1): 886. 12 October 2017

Activating de novo mutations in NFE2L2 encoding NRF2 cause a multisystem disorder.
Huppke, P. and Weissbach, S. and Church, J.A. and Schnur, R. and Krusen, M. and Dreha-Kulaczewski, S. and Kühn-Velten, W.N. and Wolf, A. and Huppke, B. and Millan, F. and Begtrup, A. and Almusafri, F. and Thiele, H. and Altmüller, J. and Nürnberg, P. and Müller, M. and Gärtner, J.
Nature Communications 8 (1): 818. 10 October 2017

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A. and van den Bruck, D. and Ciolli Mattioli, C. and Franke, V. and Imami, K. and McShane, E. and Moreno-Estelles, M. and Calviello, L. and Filipchyk, A. and Peguero-Sanchez, E. and Müller, T. and Woehler, A. and Birchmeier, C. and Merino, E. and Rajewsky, N. and Ohler, U. and Mazzoni, E.O. and Selbach, M. and Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Retinol saturase coordinates liver metabolism by regulating ChREBP activity.
Heidenreich, S. and Witte, N. and Weber, P. and Goehring, I. and Tolkachov, A. and von Loeffelholz, C. and Döcke, S. and Bauer, M. and Stockmann, M. and Pfeiffer, A.F.H. and Birkenfeld, A.L. and Pietzke, M. and Kempa, S. and Muenzner, M. and Schupp, M.
Nature Communications 8 (1): 384. 30 August 2017

The endothelial transcription factor ERG mediates angiopoietin-1-dependent control of notch signalling and vascular stability.
Shah, A.V. and Birdsey, G.M. and Peghaire, C. and Pitulescu, M.E. and Dufton, N.P. and Yang, Y. and Weinberg, I. and Osuna Almagro, L. and Payne, L. and Mason, J.C. and Gerhardt, H. and Adams, R.H. and Randi, A.M.
Nature Communications 8 : 16002. 11 July 2017

Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression.
Kar, G. and Kim, J.K. and Kolodziejczyk, A.A. and Natarajan, K.N. and Torlai Triglia, E. and Mifsud, B. and Elderkin, S. and Marioni, J.C. and Pombo, A. and Teichmann, S.A.
Nature Communications 8 (1): 36. 26 June 2017

Identification of the elementary structural units of the DNA damage response.
Natale, F. and Rapp, A. and Yu, W. and Maiser, A. and Harz, H. and Scholl, A. and Grulich, S. and Anton, T. and Hoerl, D. and Chen, W. and Durante, M. and Taucher-Scholz, G. and Leonhardt, H. and Cardoso, M.C.
Nature Communications 8 : 15760. 12 June 2017

Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions.
Hessenberger, M. and Zerbes, R.M. and Rampelt, H. and Kunz, S. and Xavier, A.H. and Purfürst, B. and Lilie, H. and Pfanner, N. and van der Laan, M. and Daumke, O.
Nature Communications 8 : 15258. 31 May 2017

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts.
Huang, K.L. and Li, S. and Mertins, P. and Cao, S. and Gunawardena, H.P. and Ruggles, K.V. and Mani, D.R. and Clauser, K.R. and Tanioka, M. and Usary, J. and Kavuri, S.M. and Xie, L. and Yoon, C. and Qiao, J.W. and Wrobel, J. and Wyczalkowski, M.A. and Erdmann-Gilmore, P. and Snider, J.E. and Hoog, J. and Singh, P. and Niu, B. and Guo, Z. and Sun, S.Q. and Sanati, S. and Kawaler, E. and Wang, X. and Scott, A. and Ye, K. and McLellan, M.D. and Wendl, M.C. and Malovannaya, A. and Held, J.M. and Gillette, M.A. and Fenyö, D. and Kinsinger, C.R. and Mesri, M. and Rodriguez, H. and Davies, S.R. and Perou, C.M. and Ma, C. and Townsend, R.R. and Chen, X. and Carr, S.A. and Ellis, M.J. and Ding, L.
Nature Communications 8 : 14864. 28 March 2017

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N. and Naumann, H. and Ruzittu, S. and Mah, N. and Pongrac, I.M. and Cozzitorto, C. and Hommel, A. and Andrade-Navarro, M.A. and Bonifacio, E. and Spagnoli, F.M.
Nature Communications 8 : 14127. 13 February 2017

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Schütte, M. and Risch, T. and Abdavi-Azar, N. and Boehnke, K. and Schumacher, D. and Keil, M. and Yildiriman, R. and Jandrasits, C. and Borodina, T. and Amstislavskiy, V. and Worth, C.L. and Schweiger, C. and Liebs, S. and Lange, M. and Warnatz, H.J. and Butcher, L.M. and Barrett, J.E. and Sultan, M. and Wierling, C. and Golob-Schwarzl, N. and Lax, S. and Uranitsch, S. and Becker, M. and Welte, Y. and Regan, J.L. and Silvestrov, M. and Kehler, I. and Fusi, A. and Kessler, T. and Herwig, R. and Landegren, U. and Wienke, D. and Nilsson, M. and Velasco, J.A. and Garin-Chesa, P. and Reinhard, C. and Beck, S. and Schäfer, R. and Regenbrecht, C.R.A. and Henderson, D. and Lange, B. and Haybaeck, J. and Keilholz, U. and Hoffmann, J. and Lehrach, H. and Yaspo, M.L.
Nature Communications 8 : 14262. 10 February 2017

DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.
Mamlouk, S. and Childs, L.H. and Aust, D. and Heim, D. and Melching, F. and Oliveira, C. and Wolf, T. and Durek, P. and Schumacher, D. and Blaeker, H. and von Winterfeld, M. and Gastl, B. and Moehr, K. and Menne, A. and Zeugner, S. and Redmer, T. and Lenze, D. and Tierling, S. and Moebs, M. and Weichert, W. and Folprecht, G. and Blanc, E. and Beule, D. and Schaefer, R. and Morkel, M. and Klauschen, F. and Leser, U. and Sers, C.
Nature Communications 8 : 14093. 25 January 2017

How EF-Tu can contribute to efficient proofreading of aa-tRNA by the ribosome.
Noel, J.K. and Whitford, P.C.
Nature Communications 7 : 13314. 31 October 2016

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A. and Roske, Y. and Barth, C. and Lleras Forero, L. and Bravo-Rodriguez, K. and Redel, Al. and Kostova, S. and McShane, E. and Opitz, R. and Faelber, K. and Rau, K. and Mielke, T. and Daumke, O. and Selbach, M. and Sanchez-Garcia, E. and Rocks, O. and Panáková, D. and Heinemann, U. and Wanker, E.E.
Nature Communications 7 : 13047. 20 October 2016

Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L. and Czajkowski, M.T. and Barth, C. and Müller, P.M. and McShane, E. and Grunwald, S. and Beaudette, P. and Mecklenburg, N. and Volkmer, R. and Zühlke, K. and Dittmar, G. and Selbach, M. and Hammes, A. and Daumke, O. and Klussmann, E. and Urbé, S. and Rocks, O.
Nature Communications 7 : 12963. 7 October 2016

Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Coscia, F. and Watters, K.M. and Curtis, M. and Eckert, M.A. and Chiang, C.Y. and Tyanova, S. and Montag, A. and Lastra, R.R. and Lengyel, E. and Mann, M.
Nature Communications 7 : 12645. 26 August 2016

reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in CD4(+) memory T cells.
Kinkley, S. and Helmuth, J. and Polansky, J.K. and Dunkel, I. and Gasparoni, G. and Froehler, S. and Chen, W. and Walter, J. and Hamann, A. and Chung, H.R.
Nature Communications 7 : 12514. 17 August 2016

Glycolytic regulation of cell rearrangement in angiogenesis.
Cruys, B. and Wong, B.W. and Kuchnio, A. and Verdegem, D. and Cantelmo, A. R. and Conradi, L.C. and Vandekeere, S. and Bouché, A. and Cornelissen, I. and Vinckier, S. and Merks, R.M.H. and Dejana, E. and Gerhardt, H. and Dewerchin, M. and Bentley, K. and Carmeliet, P.
Nature Communications 7 : 12240. 20 July 2016

Disruption of Kcc2-dependent inhibition of olfactory bulb output neurons suggests its importance in odour discrimination.
Gödde, K. and Gschwend, O. and Puchkov, D. and Pfeffer, C.K. and Carleton, A. and Jentsch, T.J.
Nature Communications 7 : 12043. 8 July 2016

Wars2 is a determinant of angiogenesis.
Wang, M. and Sips, P. and Khin, E. and Rotival, M. and Sun, X. and Ahmed, R. and Widjaja, A.A. and Schafer, S. and Yusoff, P. and Choksi, Pe.K. and Ko, N.S.J. and Singh, M.K. and Epstein, D. and Guan, Y. and Houštěk, J. and Mracek, T. and Nuskova, H. and Mikell, B. and Tan, J. and Pesce, F. and Kolar, F. and Bottolo, L. and Mancini, M. and Hubner, N. and Pravenec, M. and Petretto, E. and MacRae, C. and Cook, S.A.
Nature Communications 7 : 12061. 8 July 2016

Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3.
Van Haute, L. and Dietmann, S. and Kremer, L. and Hussain, S. and Pearce, S.F. and Powell, C.A. and Rorbach, J. and Lantaff, R. and Blanco, S. and Sauer, S. and Kotzaeridou, U. and Hoffmann, G.F. and Memari, Y. and Kolb-Kokocinski, A. and Durbin, R. and Mayr, J.A. and Frye, M. and Prokisch, H. and Minczuk, M.
Nature Communications 7 : 12039. 30 June 2016

Foldamer-mediated manipulation of a pre-amyloid toxin.
Kumar, S. and Birol, M. and Schlamadinger, D.E. and Wojcik, S.P. and Rhoades, E. and Miranker, A.D.
Nature Communications 7 : 11412. 25 April 2016

Energy efficiency trade-offs drive nucleotide usage in transcribed regions.
Chen, W.H. and Lu, G. and Bork, P. and Hu, S. and Lercher, M.J.
Nature Communications 7 : 11334. 21 April 2016

4D visualization of replication foci in mammalian cells corresponding to individual replicons.
Chagin, V.O. and Casas-Delucchi, C.S. and Reinhart, M. and Schermelleh, L. and Markaki, Y. and Maiser, A. and Bolius, J.J. and Bensimon, A. and Fillies, M. and Domaing, P. and Rozanov, Y.M. and Leonhardt, H. and Cardoso, M.C.
Nature Communications 7 : 11231. 7 April 2016

Serial interactome capture of the human cell nucleus.
Conrad, T. and Albrecht, A.-S. and Rodrigues de Melo Costa, V. and Sauer, S. and Meierhofer, D. and Ørom, U.A.
Nature Communications 7 : 11212. 4 April 2016

Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering.
Voigt, F. and Wiedemann, L. and Zuliani, C. and Querques, I. and Sebe, A. and Mátés, L. and Izsvák, Z. and Ivics, Z. and Barabas, O.
Nature Communications 7 : 11126. 30 March 2016

Cyanobacterial symbionts diverged in the late Cretaceous towards lineage-specific nitrogen fixation factories in single-celled phytoplankton.
Cornejo-Castillo, F.M. and Cabello, A.M. and Salazar, G. and Sanchez-Baracaldo, P. and Lima-Mendez, G. and Hingamp, P. and Alberti, A. and Sunagawa, S. and Bork, P. and de Vargas, C. and Raes, J. and Bowler, C. and Wincker, P. and Zehr, J.P. and Gasol, J.M. and Massana, R. and Acinas, S.G.
Nature Communications 7 : 11071. 22 March 2016

A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes.
Grabundzija, I. and Messing, S.A. and Thomas, J. and Cosby, R.L. and Bilic, I. and Miskey, C. and Gogol-Döring, A. and Kapitonov, V. and Diem, T. and Dalda, A. and Jurka, J. and Pritham, E.J. and Dyda, F. and Izsvák, Z. and Ivics, Z.
Nature Communications 7 : 10716. 2 March 2016

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children.
Korpela, K. and Salonen, A. and Virta, L.J. and Kekkonen, R.A. and Forslund, K. and Bork, P. and de Vos, W.M.
Nature Communications 7 : 10410. 26 January 2016

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells.
Klawitter, S. and Fuchs, N.V. and Upton, K.R. and Muñoz-Lopez, M. and Shukla, R. and Wang, J. and Garcia-Cañadas, M. and Lopez-Ruiz, C. and Gerhardt, D.J. and Sebe, A. and Grabundzija, I. and Merkert, S. and Gerdes, P. and Pulgarin, J.A. and Bock, A. and Held, U. and Witthuhn, A. and Haase, A. and Sarkadi, B. and Löwer, J. and Wolvetang, E.J. and Martin, U. and Ivics, Z. and Izsvák, Z. and Garcia-Perez, J.L. and Faulkner, G.J. and Schumann, G.G.
Nature Communications 7 : 10286. 8 January 2016

Structure of a bacterial type III secretion system in contact with a host membrane in situ.
Nans, A. and Kudryashev, M. and Saibil, H.R. and Hayward, R.D.
Nature Communications 6 : 10114. 11 December 2015

Cold-aggravated pain in humans caused by a hyperactive Na(V)1.9 channel mutant.
Leipold, E. and Hanson-Kahn, A. and Frick, M. and Gong, P. and Bernstein, J.A. and Voigt, M. and Katona, I. and Oliver Goral, R. and Altmüller, J. and Nürnberg, P. and Weis, J. and Hübner, C.A. and Heinemann, S.H. and Kurth, I.
Nature Communications 6 : 10049. 8 December 2015

Meta-analysis identifies seven susceptibility loci involved in the atopic march.
Marenholz, I. and Esparza-Gordillo, J. and Rüschendorf, F. and Bauerfeind, A. and Strachan, D.P. and Spycher, B.D. and Baurecht, H. and Margaritte-Jeannin, P. and Sääf, A. and Kerkhof, M. and Ege, M. and Baltic, S. and Matheson, M.C. and Li, J. and Michel, S. and Ang, W.Q. and McArdle, W. and Arnold, A. and Homuth, G. and Demenais, F. and Bouzigon, E. and Söderhäll, C. and Pershagen, G. and de Jongste, J.C. and Postma, D.S. and Braun-Fahrlaender, C. and Horak, E. and Ogorodova, L.M. and Puzyrev, V.P. and Bragina, E.Y. and Hudson, T.J. and Morin, C. and Duffy, D.L. and Marks, G.B. and Robertson, C.F. and Montgomery, G.W. and Musk, B. and Thompson, P.J. and Martin, N.G. and James, A. and Sleiman, P. and Toskala, E. and Rodriguez, E. and Fölster-Holst, R. and Franke, A. and Lieb, W. and Gieger, C. and Heinzmann, A. and Rietschel, E. and Keil, T. and Cichon, S. and Nöthen, M.M. and Pennell, C.E. and Sly, P.D. and Schmidt, C.O. and Matanovic, A. and Schneider, V. and Heinig, M. and Hübner, N. and Holt, P.G. and Lau, S. and Kabesch, M. and Weidinger, S. and Hakonarson, H. and Ferreira, M.A.R. and Laprise, C. and Freidin, M.B. and Genuneit, J. and Koppelman, G.H. and Melén, E. and Dizier, M.H. and Henderson, A.J. and Lee, Y.A.
Nature Communications 6 : 8804. 6 November 2015

Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility.
Feutlinske, F. and Browarski, M. and Ku, M.C. and Trnka, P. and Waiczies, S. and Niendorf, T. and Stallcup, W.B. and Glass, R. and Krause, E. and Maritzen, T.
Nature Communications 6 : 8535. 5 October 2015

Diffusional spread and confinement of newly exocytosed synaptic vesicle proteins.
Gimber, N. and Tadeus, G. and Maritzen, T. and Schmoranzer, J. and Haucke, V.
Nature Communications 6 : 8392. 24 September 2015

Chamber identity programs drive early functional partitioning of the heart.
Mosimann, C. and Panáková, D. and Werdich, A.A. and Musso, G. and Burger, A. and Lawson, K.L. and Carr, L.A. and Nevis, K.R. and Sabeh, M.K and Zhou, Y. and Davidson, A.J. and DiBiase, A. and Burns, C.E. and Burns, C.G. and MacRae, C.A. and Zon, L.I.
Nature Communications 6 : 8146. 26 August 2015

PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.
Serra, H. and Chivite, I. and Angulo-Urarte, A. and Soler, A. and Sutherland, J.D. and Arruabarrena-Aristorena, A. and Ragab, A. and Lim, R. and Malumbres, M. and Fruttiger, M. and Potente, M. and Serrano, M. and Fabra, A. and Vinals, F. and Casanovas, O. and Pandolfi, P.P. and Bigas, A. and Carracedo, A. and Gerhardt, H. and Graupera, M.
Nature Communications 6 : 7935. 31 July 2015

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.
Murakawa, Y. and Hinz, M. and Mothes, J. and Schuetz, A. and Uhl, M. and Wyler, E. and Yasuda, T. and Mastrobuoni, G. and Friedel, C.C. and Dölken, L. and Kempa, S. and Schmidt-Supprian, M. and Blüthgen, N. and Backofen, R. and Heinemann, U. and Wolf, J. and Scheidereit, C. and Landthaler, M.
Nature Communications 6 : 7367. 14 July 2015

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.
Aspalter, I.M. and Gordon, E. and Dubrac, A. and Ragab, A. and Narloch, J. and Vizán, P. and Geudens, I. and Collins, R.T. and Franco, C.A. and Abrahams, C.L. and Thurston, G. and Fruttiger, M. and Rosewell, I. and Eichmann, A. and Gerhardt, H.
Nature Communications 6 : 7264. 17 June 2015

Translational regulation shapes the molecular landscape of complex disease phenotypes.
Schafer, S. and Adami, E. and Heinig, M. and Costa Rodrigues, K.E. and Kreuchwig, F. and Silhavy, J. and van Heesch, S. and Simaite, D. and Rajewsky, N. and Cuppen, E. and Pravenec, M. and Vingron, M. and Cook, S.A. and Hubner, N.
Nature Communications 6 : 7200. 26 May 2015

Photoswitchable fatty acids enable optical control of TRPV1.
Frank, J.A. and Moroni, M. and Moshourab, R. and Sumser, M. and Lewin, G.R. and Trauner, D.
Nature Communications 6 : 7118. 21 May 2015

eQTL mapping identifies insertion- and deletion-specific eQTLs in multiple tissues.
Huang, J. and Chen, J. and Esparza, J. and Ding, J. and Elder, J.T. and Abecasis, G.R. and Lee, Y.A. and Lathrop, G.M. and Moffatt, M.F. and Cookson, W.O.C. and Liang, L.
Nature Communications 6 : 6821. 8 May 2015

KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations.
Fidzinski, P. and Korotkova, T. and Heidenreich, M. and Maier, N. and Schuetze, S. and Kobler, O. and Zuschratter, W. and Schmitz, D. and Ponomarenko, A. and Jentsch, T.J.
Nature Communications 6 : 6254. 4 February 2015

Roquin binding to target mRNAs involves a winged helix-turn-helix motif.
Schuetz, A. and Murakawa, Y. and Rosenbaum, E. and Landthaler, M. and Heinemann, U.
Nature Communications 5 : 5701. 11 December 2014

Chlamydia infection depends on a functional MDM2-p53 axis.
Gonzalez, E. and Rother, M. and Kerr, M.C. and Al-Zeer, M.A. and Abu-Lubad, M. and Kessler, M. and Brinkmann, V. and Loewer, A. and Meyer, T.F.
Nature Communications 5 : 5201. 13 November 2014

Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ.
Rehm, A. and Gätjen, M. and Gerlach, K. and Scholz, F. and Mensen, A. and Gloger, M. and Heinig, K. and Lamprecht, B. and Mathas, S. and Bégay, V. and Leutz, A. and Lipp, M. and Dörken, B. and Höpken, U.E.
Nature Communications 5 : 5057. 30 September 2014

Warped linear mixed models for the genetic analysis of transformed phenotypes.
Fusi, N. and Lippert, C. and Lawrence, N.D. and Stegle, O.
Nature Communications 5 : 4890. 19 September 2014

AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.
Mojallal, M. and Zheng, Y. and Hultin, S. and Audebert, S. and van Harn, T. and Johnsson, P. and Lenander, C. and Fritz, N. and Mieth, C. and Corcoran, M. and Lembo, F. and Hallstroem, M. and Hartman, J. and Mazure, N.M. and Weide, T. and Grander, D. and Borg, J.P. and Uhlen, P. and Holmgren, L.
Nature Communications 5 : 4557. 1 August 2014

WT1 controls antagonistic FGF and BMP-pSMAD pathways in early renal progenitors.
Motamedi, F.J. and Badro, D.A. and Clarkson, M. and Rita Lecca, M. and Bradford, S.T. and Buske, F.A. and Saar, K. and Hübner, N. and Bräendli, A.W. and Schedl, A.
Nature Communications 5 : 4444. 17 July 2014

MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2.
Hinkel, R. and Trenkwalder, T. and Petersen, B. and Husada, W. and Gesenhues, F. and Lee, S. and Hannappel, E. and Bock-Marquette, I. and Theisen, D. and Leitner, L. and Boekstegers, P. and Cierniewski, C. and Mueller, O.J. and le Noble, F. and Adams, R.H. and Weinl, C. and Nordheim, A. and Reichart, B. and Weber, C. and Olson, E. and Posern, G. and Deindl, E. and Niemann, H. and Kupatt, C.
Nature Communications 5 : 3970. 9 June 2014

Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance.
de Almeida, P.E. and Meyer, E.H. and Kooreman, N.G. and Diecke, S. and Dey, D. and Sanchez-Freire, V. and Hu, S. and Ebert, A. and Odegaard, J. and Mordwinkin, N.M. and Brouwer, T.P. and Lo, D. and Montoro, D.T. and Longaker, M.T. and Negrin, R.S. and Wu, J.C.
Nature Communications 5 : 3903. 30 May 2014

Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.
Aksoy, I. and Giudice, V. and Delahaye, E. and Wianny, F. and Aubry, M. and Mure, M. and Chen, J. and Jauch, R. and Bogu, G.K. and Nolden, T. and Himmelbauer, H. and Doss, M.X. and Sachinidis, A. and Schulz, H. and Hummel, O. and Martinelli, P. and Hübner, N. and Stanton, L.W. and Real, F.X. and Bourillot, P.Y. and Savatier, P.
Nature Communications 5 : 3719. 28 April 2014

Tuning piezo ion channels to detect molecular-scale movements relevant for fine touch.
Poole, K. and Herget, R. and Lapatsina, L. and Ngo, H.D. and Lewin, G.R.
Nature Communications 5 : 3520. 24 March 2014

Disrupting MLC1 and GlialCAM and ClC-2 interactions in leukodystrophy entails glial chloride channel dysfunction.
Hoegg-Beiler, M.B. and Sirisi, S. and Orozco, I.J. and Ferrer, I. and Hohensee, S. and Auberson, M. and Goedde, K. and Vilches, C. and de Heredia, M.L. and Nunes, V. and Estévez, R. and Jentsch, T.J.
Nature Communications 5 : 3475. 19 March 2014

Role of RIM1α in short- and long-term synaptic plasticity at cerebellar parallel fibres.
Kintscher, M. and Wozny, C. and Johenning, F.W. and Schmitz, D. and Breustedt, J.
Nature Communications 4 : 2392. 3 September 2013

Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1-PP2A protein complex.
Krauss, S. and Griesche, N. and Jastrzebska, E. and Chen, C. and Rutschow, D. and Achmüller, C. and Dorn, S. and Boesch, S.M. and Lalowski, M. and Wanker, E. and Schneider, R. and Schweiger, S.
Nature Communications 4 : 1511. 26 February 2013

A chronic model of arthritis supported by a strain-specific periarticular lymph node in BALB/c mice.
Baddack, U. and Hartmann, S. and Bang, H. and Grobe, J. and Loddenkemper, C. and Lipp, M. and Mueller, G.
Nature Communications 4 : 1644. 2013

A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.
Fujita, K. and Nakamura, Y. and Oka, T. and Ito, H. and Tamura, T. and Tagawa, K. and Sasabe, T. and Katsuta, A. and Motoki, K. and Shiwaku, H. and Sone, M. and Yoshida, C. and Katsuno, M. and Eishi, Y. and Murata, M. and Taylor, J.P. and Wanker, E.E. and Kono, K. and Tashiro, S. and Sobue, G. and La Spada, A.R. and Okazawa, H.
Nature Communications 4 : 1816. 2013

Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides.
Lättig-Tünnemann, G. and Prinz, M. and Hoffmann, D. and Behlke, J. and Palm-Apergi, C. and Morano, I. and Herce, H.D. and Cardoso, M.C.
Nature Communications 2 : 453. 30 August 2011

Histone acetylation controls the inactive X chromosome replication dynamics.
Casas-Delucchi, C.S. and Brero, A. and Rahn, H.P. and Solovei, I. and Wutz, A. and Cremer, T. and Leonhardt, H. and Cardoso, M.C.
Nature Communications 2 (1): 222. March 2011

Differential use of importin-alpha isoforms governs cell tropism and host adaptation of influenza virus.
Gabriel, G. and Klingel, K. and Otte, A. and Thiele, S. and Hudjetz, B. and Arman-Kalcek, G. and Sauter, M. and Shmidt, T. and Rother, F. and Baumgarte, S. and Keiner, B. and Hartmann, E. and Bader, M. and Brownlee, G.G. and Fodor, E. and Klenk, H.D.
Nature Communications 2 (1): 156. January 2011

Letter

The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing.
Goulielmaki, E. and Tsekrekou, M. and Batsiotos, N. and Ascensão-Ferreira, M. and Ledaki, E. and Stratigi, K. and Chatzinikolaou, G. and Topalis, P. and Kosteas, T. and Altmüller, J. and Demmers, J.A. and Barbosa-Morais, N.L. and Garinis, G.A.
Nature Communications 12 (1): 3153. 26 May 2021