Article

Rapid and profound treatment response of difficult-to-treat rheumatoid arthritis to CD19 CAR T-cell therapy.
Albach, Fredrik N., Minopoulou, Ioanna, Wilhelm, Artur, Kleyer, Arnd, Wiebe, Edgar, Fleischmann, Anja, Engel, Klaus, Frick, Mareike, Damm, Frederik, Gogolok, Julia, Serve, Sebastian, Locher, Benjamin, Borie, Dominic, Phithak, Elpida, Hinkelmann, Lukas, Ohrndorf, Sarah, Casteleyn, Vincent, Biesen, Robert, Sattler, Arne, Dörner, Thomas, Drzeniek, Norman M., Alexander, Tobias, Zernicke, Jan, Unterwalder, Nadine, Movassaghi, Kamran, Hütter-Krönke, Marie Luise, Schrezenmeier, Eva, Schreiber, Adrian ORCID: https://orcid.org/0000-0003-1244-6379, Furth, Christian, Schett, Georg, Schneider, Udo, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Krönke, Gerhard, Penack, Olaf and Simon, David ORCID: https://orcid.org/0000-0001-8310-7820
EULAR Rheumatology Open June 2026

Heart failure therapy in patients with advanced cancer receiving specialized palliative care (EMPATICC trial).
Anker, Markus S. ORCID: https://orcid.org/0000-0002-4406-8555, Mahabadi, Amir A., Totzeck, Matthias, Tewes, Mitra, Shahzeb Khan, Muhammad, Mincu, Raluca I., Hendgen-Cotta, Ulrike B., Michel, Lars, Mathew, Baicy, Drescher, Ophelia, Schuler, Martin, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Rieger, Kathrin, Ahn, Johann, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Modest, Dominik P., Denecke, Corinna, Kretzler, Lucie, Ramer, Luisa V., Krug, Danara, Landmesser, Ulf, Lehmann, Lorenz, Frey, Norbert, Bercker, Sven, Laufs, Ulrich, Böhm, Michael, Mahfoud, Felix ORCID: https://orcid.org/0000-0002-4425-549X, Merkely, Bela, Diek, Monika, Butler, Javed, Veiser, Anja, Heise, Tim, Hellmich, Martin, Placzek, Marius, Friede, Tim ORCID: https://orcid.org/0000-0001-5347-7441, Anker, Stefan D. and Rassaf, Tienush
European Heart Journal 47 (9): 1034-1046. 1 March 2026

Clinical and echocardiographic phenotype of cardiac wasting in patients with advanced cancer.
Anker, Markus S. ORCID: https://orcid.org/0000-0002-4406-8555, Khan, Muhammad Shahzeb, Nikolski, Anja, Porthun, Jan, Arshad, Muhammad Sameer, Hadzibegovic, Sara, Lena, Alessia, Kretzler, Lucie, Hella, Jonathan L., Witkowski, Marco, Rieger, Kathrin, Ahn, Johann, Modest, Dominik P., Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Totzeck, Matthias, Mahabadi, Amir A., Rassaf, Tienush, Buchmann, Nikolaus, Attanasio, Philipp, Zeller, Tanja, Karakas, Mahir, Tocchetti, Carlo G., Wilkenshoff, Ursula, Cleland, John G.F., von Haehling, Stephan, Butler, Javed and Landmesser, Ulf
European Journal of Heart Failure 27 (11): 2130-2140. November 2025

The prognostic role of frailty and its recognition with simple FRAIL and fried frailty questionnaires in advanced cancer patients.
Weinländer, Pia, Hadzibegovic, Sara, Porthun, Jan, Kretzler, Lucie, Evertz, Ruben, Lena, Alessia, Lück, Laura-Carina, Hella, Jonathan L, Wilkenshoff, Ursula, Stroux, Andrea, Keramida, Kalliopi, Letsch, Anne, Modest, Dominik Paul, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Karakas, Mahir, Abdelwahed, Youssef S., Attanasio, Philipp, Rauch, Ursula, Skurk, Carsten, Doehner, Wolfram, Landmesser, Ulf, von Haehling, Stephan and Anker, Markus S.
Journal of Cachexia Sarcopenia and Muscle 16 (5): e70076. October 2025

Association of an impaired GH‑IGF‑I axis with cardiac wasting in patients with advanced cancer.
Fröhlich, A.K., Porthun, J., Talha, K.M., Lena, A., Hadzibegovic, S., Wilkenshoff, U., Sonntag, F., Nikolski, A., Ramer, L.V., Zeller, T., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Anker, S.D., Haverkamp, W., von Haehling, S., Doehner, W., Rauch, U., Skurk, C., Cleland, J.G.F., Butler, J., Coats, A.J.S., Landmesser, U., Karakas, M. and Anker, M.S. ORCID: https://orcid.org/0000-0002-4406-8555
Clinical Research in Cardiology 114 (9): 1118-1132. September 2025

New cardiovascular biomarkers in patients with advanced cancer – a prospective study comparing MR-proADM, MR-proANP, copeptin, high-sensitivity troponin T and NT-proBNP.
Anker, M.S. ORCID: https://orcid.org/0000-0002-4406-8555, Lück, L.C., Khan, M.S., Porthun, J., Hadzibegovic, S., Lena, A., Wilkenshoff, U., Weinländer, P., Evertz, R., Totzeck, M., Mahabadi, A.A., Rassaf, T., Anker, S.D. ORCID: https://orcid.org/0000-0002-4406-8555, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Karakas, M., Landmesser, U., Butler, J. and von Haehling, S.
European Journal of Heart Failure 27 (6): 1047-1055. June 2025

Outcomes with intensive treatment for acute myeloid leukemia: an analysis of two decades of data from the HARMONY Alliance.
Sobas, M.A., Turki, A.T., Ramiro, A.V., Sánchez, A.H., Elicegui, J.M., González, T., Melchor, R.A., Abáigar, M., Tur, L., Dall'Olio, D., Sträng, E., Tettero, J.M., Castellani, G., Benner, A., Döhner, K., Thiede, C., Metzeler, K.H., Haferlach, T., Damm, F., Ayala, R., Martínez-López, J., Mills, K.I., Sierra, J., Lehmann, S., Porta, M.G.D., Mayer, J., Reinhardt, D., Medina, R.V., Schulze-Rath, R., Barbus, M., Hernández-Rivas, J.M., Huntly, B.J.P., Ossenkoppele, G., Döhner, H. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Haematologica 110 (5): 1126-1140. May 2025

Therapy adherence after interdisciplinary tumour board discussion is associated with improved outcome in soft tissue sarcoma: a Charité Comprehensive Cancer Centre analysis.
Strönisch, A. ORCID: https://orcid.org/0000-0002-0961-4602, Rau, D., Wittenberg, S., Kaul, D., Koulaxouzidis, G., Öllinger, R., von Laffert, M., Jarosch, A., Schäfer, F., Keilholz, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Märdian, S., Striefler, J. and Flörcken, A.
International Journal of Cancer 156 (4): 802-816. 15 February 2025

Advanced disease and CD8(+) TEMRA cells predict severe infections in multiple myeloma.
Tranter, E., Busch, D., Heck, C., Blau, I.W., Nogai, A., Schiele, P., Meisel, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Frentsch, M. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Frontiers in Immunology 16 12 February 2025

Acute promyelocytic leukemia: long-term outcomes from the HARMONY project.
Voso, M.T., Guarnera, L., Lehmann, S., Döhner, K., Döhner, H., Platzbecker, U., Russell, N.H., Dillon, R.J., Thomas, I., Ossenkoppele, G.J., Haferlach, T., Vignetti, M., La Sala, E., Piciocchi, A., Fazi, P., Villaverde Ramiro, Á., Tur Giménez, L., Gurnari, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Hernandez, J.M.
Blood 145 (2): 234-243. 9 January 2025

Measurable residual disease monitoring in AML with FLT3-ITD treated with intensive chemotherapy plus midostaurin.
Rücker, F.G., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Cocciardi, S., Skambraks, S., Luck, T.J., Weber, D., Krzykalla, J., Pozek, E., Schneider, I.J., Corbacioglu, A., Gaidzik, V.I., Meid, A., Aicher, S., Stegelmann, F., Schrade, A., Theis, F., Fiedler, W., Salih, H.R., Wulf, G.G., Salwender, H.J., Schroeder, T., Götze, K.S., Kühn, M.W.M., Lübbert, M., Schlenk, R.F., Benner, A., Thol, F.R., Heuser, M., Ganser, A., Döhner, H. and Döhner, K.
Blood Advances 8 (23): 6067-6080. 10 December 2024

In vitro testing of drug response in primary multiple myeloma cells using a microwell-based technology.
Krüger, J., Blau, I.W., Blau, O., Bettelli, A., Rocchi, L., Bocchi, M., Krönke, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Nogai, A.
Leukemia Research 147 : 107599. December 2024

Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype.
Leppä, A.M. ORCID: https://orcid.org/0000-0003-0849-1759, Grimes, K. ORCID: https://orcid.org/0000-0002-4805-2366, Jeong, H. ORCID: https://orcid.org/0000-0002-1526-3343, Huang, F.Y. ORCID: https://orcid.org/0000-0002-2163-9300, Andrades, A., Waclawiczek, A., Boch, T., Jauch, A., Renders, S., Stelmach, P. ORCID: https://orcid.org/0009-0000-5270-4761, Müller-Tidow, C. ORCID: https://orcid.org/0000-0002-7166-5232, Karpova, D., Sohn, M., Grünschläger, F., Hasenfeld, P., Benito Garagorri, E., Thiel, V., Dolnik, A. ORCID: https://orcid.org/0000-0003-4166-2900, Rodriguez-Martin, B., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mrózek, K. ORCID: https://orcid.org/0000-0002-1408-5063, Eisfeld, A.K. ORCID: https://orcid.org/0000-0001-6442-1419, Krämer, A., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Korbel, J.O. ORCID: https://orcid.org/0000-0002-2798-3794 and Trumpp, A. ORCID: https://orcid.org/0000-0002-6212-3466
Nature Genetics 56 (12): 2790-2803. December 2024

Tracking rare single donor and recipient immune and leukemia cells after allogeneic hematopoietic cell transplantation using mitochondrial DNA mutations.
Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, N., Maurer, K., Kwok, M., Lyu, H., Lu, W.S., Oliveira, G., Gohil, S.H., Leshchiner, I., Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, D.S., Kim, H.T., Li, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, J., Getz, G., Garcia, J.S., Soiffer, R.J., Livak, K.J. and Wu, C.J.
Blood Cancer Discovery 5 (6): 442-459. 1 November 2024

Increased abundance of Firmicutes and depletion of Bacteroidota predicts poor outcome in chronic lymphocytic leukemia.
Paziewska, M., Szelest, Mo., Kiełbus, M., Masternak, M., Zaleska, J., Wawrzyniak, E., Kotkowska, A., Siemieniuk-Ryś, M., Morawska, M., Kalicińska, E., Jabłonowska, P., Wróbel, T., Wolska-Washer, A., Błoński, J.Z., Robak, T., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Giannopoulos, K.
Oncology letters 28 (5): 552. November 2024

Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13).
Weichenhan, D., Riedel, A., Sollier, E., Toprak, U.H., Hey, J., Breuer, K.H., Wierzbinska, J.A., Touzart, A., Lutsik, P., Bähr, M., Östlund, A., Nilsson, T., Jacobsson, S., Waraky, A., Behrens, Y.L., Göhring, G., Schlegelberger, B., Steinek, C., Harz, H., Leonhardt, H., Dolnik, A., Reinhardt, D., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Palmqvist, L., Lipka, D.B. and Plass, C.
Blood Advances 8 (19): 5100-5111. 8 October 2024

Therapy-related AML: long-term outcome in a large cohort of AML-patients with intensive and non-intensive therapy.
Gross, S., Ihlow, J. ORCID: https://orcid.org/0000-0001-5484-1321, Busack, L., Adamiak, K., Schrezenmeier, J. ORCID: https://orcid.org/0000-0001-5239-4513, Jesse, J., Schwarz, M., Flörcken, A., Vuong, L.G., Rieger, K., Krönke, J. ORCID: https://orcid.org/0000-0002-4649-0506, le Coutre, P., Boldt, V., von Brünneck, A.C., Horst, D., Burmeister, T. ORCID: https://orcid.org/0000-0003-4843-2876, Blau, I.W., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Westermann, J.
Blood Cancer Journal 14 (1): 160. 16 September 2024

Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study.
Hernández-Sánchez, A. ORCID: https://orcid.org/0000-0002-6601-3096, González, T., Sobas, M., Sträng, E., Castellani, G. ORCID: https://orcid.org/0000-0003-4892-925X, Abáigar, M., Valk, P.J.M. ORCID: https://orcid.org/0000-0002-8857-9461, Villaverde Ramiro, Á. ORCID: https://orcid.org/0000-0002-7337-7218, Benner, A., Metzeler, K.H. ORCID: https://orcid.org/0000-0003-3920-7490, Azibeiro, R., Tettero, J.M. ORCID: https://orcid.org/0000-0002-0811-0824, Martínez-López, J. ORCID: https://orcid.org/0000-0001-7908-0063, Pratcorona, M., Martínez Elicegui, J. ORCID: https://orcid.org/0000-0001-5294-6162, Mills, K.I. ORCID: https://orcid.org/0000-0002-6362-4481, Thiede, C. ORCID: https://orcid.org/0000-0003-1241-2048, Sanz, G. ORCID: https://orcid.org/0000-0002-2767-8191, Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862, Heuser, M. ORCID: https://orcid.org/0000-0001-5318-9044, Haferlach, T. ORCID: https://orcid.org/0000-0003-0196-2837, Turki, A.T. ORCID: https://orcid.org/0000-0003-1347-3360, Reinhardt, D., Schulze-Rath, R., Barbus, M., Hernández-Rivas, J.M., Huntly, B. ORCID: https://orcid.org/0000-0003-0312-161X, Ossenkoppele, G., Döhner, H. ORCID: https://orcid.org/0000-0003-2116-5536 and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Leukemia 38 (9): 1929-1937. September 2024

Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients.
Halik, A., Tilgner, M., Silva, P., Estrada, N., Altwasser, R. ORCID: https://orcid.org/0009-0002-6216-6068, Jahn, E., Heuser, M., Hou, H.A., Pratcorona, M., Hills, R.K., Metzeler, K.H., Fenwarth, L., Dolnik, A., Terre, C., Kopp, K., Blau, O., Szyska, M. ORCID: https://orcid.org/0000-0002-4213-4600, Christen, F., Krönke, J., Vasseur, L., Löwenberg, B., Esteve, J., Valk, P.J.M., Duchmann, M., Chou, W.C., Linch, D.C., Döhner, H., Gale, R.E., Döhner, K., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Yoshida, K. and Damm, F.
Journal of Hematology & Oncology 17 (1): 70. 19 August 2024

The proteogenomic landscape of multiple myeloma reveals insights into disease biology and therapeutic opportunities.
Ramberger, E. ORCID: https://orcid.org/0000-0003-2760-2696, Sapozhnikova, V., Ng, Y.L.D., Dolnik, A., Ziehm, M. ORCID: https://orcid.org/0000-0001-7074-4054, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Sträng, E., Kull, M., Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Krüger, J. ORCID: https://orcid.org/0000-0001-5789-4082, Benary, M. ORCID: https://orcid.org/0000-0002-3067-2030, Müller, S. ORCID: https://orcid.org/0009-0003-6363-5599, Gao, X., Murgai, A. ORCID: https://orcid.org/0000-0001-9767-7402, Haji, M., Schmidt, A., Lutz, R., Nogai, A., Braune, J. ORCID: https://orcid.org/0000-0003-2026-2641, Laue, D. ORCID: https://orcid.org/0000-0002-7237-9414, Langer, C., Khandanpour, C., Bassermann, F. ORCID: https://orcid.org/0000-0003-4435-2609, Döhner, H. ORCID: https://orcid.org/0000-0003-2116-5536, Engelhardt, M. ORCID: https://orcid.org/0000-0003-0405-1676, Straka, C., Hundemer, M. ORCID: https://orcid.org/0000-0002-5596-2405, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Einsele, H. ORCID: https://orcid.org/0000-0002-7680-0819, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Knop, S. ORCID: https://orcid.org/0000-0003-1276-6639, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X and Krönke, J.
Nature Cancer 5 (8): 1267-1284. August 2024

Effective symptom relief through continuous integration of palliative care in advanced renal cell carcinoma patients: comprehensive measurement using the palliative care base assessment.
Dörr, A. ORCID: https://orcid.org/0009-0005-4464-307X, Vogel, I., Wittenbecher, F., Westermann, J., Thuss-Patience, P., Ahn, J. ORCID: https://orcid.org/0000-0002-5631-4143, Pelzer, U., Hardt, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Flörcken, A. ORCID: https://orcid.org/0000-0001-6462-7214
Palliative Care and Social Practice 18 : 26323524241260424. 24 June 2024

Dynamics of clonal hematopoiesis under DNA-damaging treatment in patients with ovarian cancer.
Arends, C.M. ORCID: https://orcid.org/0000-0003-4417-4750, Kopp, K., Hablesreiter, R. ORCID: https://orcid.org/0000-0002-4586-932X, Estrada, N., Christen, F. ORCID: https://orcid.org/0000-0001-8868-2533, Moll, U.M., Zeillinger, R., Schmitt, W.D. ORCID: https://orcid.org/0000-0002-7870-138X, Sehouli, J., Kulbe, H., Fleischmann, M., Ray-Coquard, I., Zeimet, A., Raspagliesi, F., Zamagni, C., Vergote, I., Lorusso, D., Concin, N., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Braicu, E.I. and Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173
Leukemia 38 (6): 1378-1389. June 2024

Oligonucleotide library screening for identification of virus-specific T-cell receptors.
Welters, M.L., Stadler, S., Anastasopoulou, V., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Leisegang, M. ORCID: https://orcid.org/0000-0003-3692-7142, Kammertöns, T. ORCID: https://orcid.org/0000-0003-3309-5141, Welters, C. ORCID: https://orcid.org/0000-0002-3098-9003 and Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128
European Journal of Immunology 56 (6): e2350908. June 2024

Update and European consensus on a patient-centered core outcome set for multiple myeloma in clinical practice and research.
Oerlemans, S., De Rooij, B.H., Bennink, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Broijl, A., D'Agostino, M., Laane, E., Lupo-Stanghellini, M.T., Perrot, A., Wester, R., Cursaru, V., Scheurer, H., Vesseur, J., Dalal, M., Sen, R., Stamm, T., Ludwig, H. and Sonneveld, P.
Haematologica 109 (6): 1956-1959. June 2024

Thrombus or tumor? A case report of a rare sarcoma entity: intimal sarcoma of the pulmonary arteries.
Dörr, A., Flörcken, A, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Capper, D., Von Deimling, A., Kaul, D., Märdian, S., Starck, C., Horst, D., Dragomir, M.P., Schäfer, F.M. and Jarosch, A.
Molecular Biology Reports 51 : 568. 24 April 2024

Diagnosing recipient- vs. donor-derived posttransplant myelodysplastic neoplasm via targeted single-cell mutational profiling.
Ihlow, J., Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207, Vuong, L.G., Bischoff, P., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Trinks, A. ORCID: https://orcid.org/0000-0001-9983-1506, Blau, O., Behnke, A., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Morkel, M. ORCID: https://orcid.org/0000-0002-2553-9999, Wu, C.J., Westermann, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, von Brünneck, A.C., Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447, Horst, D. and Praktiknjo, S.D. ORCID: https://orcid.org/0000-0002-0186-5271
Med 6 (4): 100548. 11 April 2024

Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry.
Ben Hamza, A., Welters, C., Stadler, S., Brüggemann, M., Dietze, K., Brauns, O., Brümmendorf, T.H., Winkler, T.H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Rosenberger, L., Leisegang, M., Kammertöns, T., Herr, W., Moosmann, A., Strobel, J., Hackstein, H., Dornmair, K., Beier, F. and Hansmann, L.
Blood 143 (14): 1365-1378. 4 April 2024

HLA-C*04:09N is expressed at the cell surface and triggers peptide-specific T-cell activation.
Welters, C., Welters, M.L., Stadler, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Strobel, J., Hackstein, H., Dhamodaran, A. ORCID: https://orcid.org/0000-0001-7711-9593, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128
Haematologica 109 (4): 1121-1127. April 2024

Comparable CD8(+) T-cell responses to SARS-CoV-2 vaccination in single-cell transcriptomics of recently allogeneic transplanted patients and healthy individuals.
Tranter, E. ORCID: https://orcid.org/0000-0001-7752-4126, Frentsch, M., Hütter-Krönke, M.L. ORCID: https://orcid.org/0000-0002-4531-9889, Vuong, G.L., Busch, D., Loyal, L. ORCID: https://orcid.org/0000-0001-5738-4437, Henze, L. ORCID: https://orcid.org/0000-0002-6540-4263, Rosnev, S., Blau, I.W., Thiel, A. ORCID: https://orcid.org/0000-0002-5515-4002, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Journal of Medical Virology 96 (3): e29539. March 2024

Covering hierarchical dirichlet mixture models on binary data to enhance genomic stratifications in onco-hematology.
Dall'Olio, D. ORCID: https://orcid.org/0000-0003-0196-6870, Sträng, E., Turki, A.T., Tettero, J.M., Barbus, M., Schulze-Rath, R. ORCID: https://orcid.org/0000-0003-4589-7213, Elicegui, J.M., Matteuzzi, T., Merlotti, A. ORCID: https://orcid.org/0000-0002-3648-2828, Carota, L., Sala, C. ORCID: https://orcid.org/0000-0002-4889-1047, Della Porta, M.G., Giampieri, E., Hernández-Rivas, J.M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Castellani, G.
PLoS Computational Biology 20 (2): e1011299. 2 February 2024

Genetic characterization of primary mediastinal B-cell lymphoma: pathogenesis and patient outcomes.
Noerenberg, D., Briest, F., Hennch, C., Yoshida, K., Hablesreiter, R., Takeuchi, Y., Ueno, H., Staiger, A.M., Ziepert, M., Asmar, F., Locher, B.N., Toth, E., Weber, T., Amini, R.M., Klapper, W., Bouzani, M., Poeschel, V., Rosenwald, A., Held, G., Campo, E., Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X, Stamatopoulos, K., Kanellis, G., Anagnostopoulos, I., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Goldschmidt, N., Zinzani, P.L., Bödör, C., Rosenquist, R., Vassilakopoulos, T.P., Ott, G., Ogawa, S. and Damm, F.
Journal of Clinical Oncology 42 (4): 452-466. 1 February 2024

Successful generation of fully human, second generation, anti-CD19 CAR T cells for clinical use in patients with diverse autoimmune disorders.
Mougiakakos, D., Sengupta, R., Gold, R., Schroers, R., Haghikia, A., Lorente, M., Pendleton, M., Register, A., Heesen, C., Kröger, N., Schett, G., Mackensen, A., Podoll, A., Gutman, J., Furie, R., Bayer, R., Distler, J.H.W., Dietrich, S., Krönke, G., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Walker, K.
Cytotherapy 27 (2): 236-246. February 2024

Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia.
Bruedigam, C. ORCID: https://orcid.org/0000-0002-9580-1446, Porter, A.H., Song, A., Vroeg In de Wei, G., Stoll, T., Straube, J. ORCID: https://orcid.org/0000-0002-1748-0659, Cooper, L., Cheng, G., Kahl, V.F.S., Sobinoff, A.P., Ling, V.Y. ORCID: https://orcid.org/0000-0001-9757-1229, Jebaraj, B.M.C., Janardhanan, Y., Haldar, R., Bray, L.J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Heidel, F.H., Kennedy, G.A., Hill, M.M., Pickett, H.A., Abdel-Wahab, O. ORCID: https://orcid.org/0000-0002-3907-6171, Hartel, G. ORCID: https://orcid.org/0000-0002-5454-6450 and Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209
Nature Cancer 5 (1): 47-65. January 2024

AML with complex karyotype: extreme genomic complexity revealed by combined long-read sequencing and Hi-C technology.
Klever, M.K., Sträng, E., Hetzel, S., Jungnitsch, J., Dolnik, A., Schöpflin, R., Schrezenmeier, J.F.F., Schick, F., Blau, O., Westermann, J., Rücker, F.G., Xia, Z., Döhner, K., Schrezenmeier, H., Spielmann, M., Meissner, A., Melo, U.S., Mundlos, S. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Blood Advances 7 (21): 6520-6531. 14 November 2023

Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients.
Jahn, E. ORCID: https://orcid.org/0009-0001-0741-1166, Saadati, M., Fenaux, P., Gobbi, M., Roboz, G.J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Lutsik, P., Riedel, A., Plass, C. ORCID: https://orcid.org/0000-0003-2554-3952, Jahn, N., Walter, C., Holzmann, K., Hao, Y., Naim, S., Schreck, N., Krzykalla, J., Benner, A. ORCID: https://orcid.org/0000-0002-7238-6956, Keer, H.N., Azab, M., Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862 and Döhner, H. ORCID: https://orcid.org/0000-0003-2116-5536
Leukemia 37 (11): 2187-2196. November 2023

Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Briest, F. ORCID: https://orcid.org/0000-0001-5969-9467, Noerenberg, D., Hennch, C. ORCID: https://orcid.org/0000-0003-4104-5531, Yoshida, K. ORCID: https://orcid.org/0000-0003-4612-2778, Hablesreiter, R. ORCID: https://orcid.org/0000-0002-4586-932X, Nimo, J. ORCID: https://orcid.org/0000-0002-1565-7799, Sasca, D. ORCID: https://orcid.org/0000-0003-0330-7959, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Mansouri, L., Inoue, Y., Wiegand, L. ORCID: https://orcid.org/0000-0002-9917-7396, Staiger, A.M. ORCID: https://orcid.org/0000-0002-5896-3200, Casadei, B., Korkolopoulou, P., Weiner, J. ORCID: https://orcid.org/0000-0003-1438-7819, Lopez-Guillermo, A., Warth, A., Schneider, T., Nagy, Á. ORCID: https://orcid.org/0000-0001-6118-0365, Klapper, W., Hummel, M. ORCID: https://orcid.org/0000-0001-6717-605X, Kanellis, G., Anagnostopoulos, I. ORCID: https://orcid.org/0000-0002-5043-6043, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Rosenquist, R. ORCID: https://orcid.org/0000-0002-0211-8788, Vassilakopoulos, T.P., Ott, G., Ogawa, S. ORCID: https://orcid.org/0000-0002-7778-5374 and Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173
Leukemia 37 (11): 2237-2249. November 2023

Predictive value of DNA methylation patterns in AML patients treated with an azacytidine containing induction regimen.
Schmutz, M., Zucknick, M., Schlenk, R.F., Mertens, D., Benner, A., Weichenhan, D., Mücke, O., Döhner, K., Plass, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Claus, R.
Clinical Epigenetics 15 (1): 171. 26 October 2023

Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.
Eifert, T., Hsu, C.J., Becker, A.L., Graessle, S. ORCID: https://orcid.org/0000-0002-5260-6392, Horne, A. ORCID: https://orcid.org/0000-0002-4209-4573, Bemmann, F. ORCID: https://orcid.org/0009-0007-0533-7138, Zhang, Q., Heuser, M. ORCID: https://orcid.org/0000-0001-5318-9044, Vasioukhin, V., Scholl, S., Hochhaus, A. ORCID: https://orcid.org/0000-0003-0626-0834, Siegerist, F., Endlich, N., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Schnoeder, T.M and Heidel, F.H. ORCID: https://orcid.org/0000-0003-2438-1955
Leukemia 37 (10): 2027-2035. October 2023

Clinical implications and dynamics of clonal hematopoiesis in anti-CD19 CAR T-cell treated patients.
Panagiota, V., Kerschbaum, J.F., Penack, O., Stein, C.M., Arends, C.M., Koenecke, C., Strzelecka, P.M. ORCID: https://orcid.org/0000-0003-0226-6788, Kloos, A., Wiegand, L., Lasch, A., Altwasser, R. ORCID: https://orcid.org/0009-0002-6216-6068, Halik, A., Gabdoulline, R., Thomson, J., Weibl, K., Franke, G.N., Berger, C., Hasenkamp, J., Ayuk, F., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Beutel, G., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Wulf, G.G., Kröger, N., Vucinic, V., Heuser, M. and Damm, F.
HemaSphere 7 (10): e957. October 2023

The recurrent atypical e8a2 BCR::ABL1 transcript with insertion of an inverted 55 base pair ABL1 intron 1b sequence: a detailed molecular analysis.
Burmeister, T., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and le Coutre, P.
Acta Haematologica 146 (5): 413-418. October 2023

Severe hematotoxicity after CD19 CAR-T therapy is associated with suppressive immune dysregulation and limited CAR-T expansion.
Rejeski, K. ORCID: https://orcid.org/0000-0003-3905-0251, Perez, A., Iacoboni, G. ORCID: https://orcid.org/0000-0003-0805-9288, Blumenberg, V. ORCID: https://orcid.org/0000-0003-1379-0876, Bücklein, V.L. ORCID: https://orcid.org/0000-0001-7391-7280, Völkl, S. ORCID: https://orcid.org/0000-0003-2193-3048, Penack, O., Albanyan, O. ORCID: https://orcid.org/0000-0003-4802-5445, Stock, S. ORCID: https://orcid.org/0000-0002-5072-5013, Müller, F. ORCID: https://orcid.org/0000-0001-5487-5839, Karschnia, P. ORCID: https://orcid.org/0000-0002-1254-5310, Petrera, A., Reid, K. ORCID: https://orcid.org/0000-0002-6585-0781, Faramand, R. ORCID: https://orcid.org/0000-0001-7750-781X, Davila, M.L. ORCID: https://orcid.org/0000-0002-6270-3065, Modi, K. ORCID: https://orcid.org/0000-0003-3351-8829, Dean, E.A. ORCID: https://orcid.org/0000-0003-3153-223X, Bachmeier, C. ORCID: https://orcid.org/0000-0002-9832-3670, von Bergwelt-Baildon, M., Locke, F.L., Bethge, W. ORCID: https://orcid.org/0000-0001-6052-2618, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mackensen, A. ORCID: https://orcid.org/0000-0002-0685-4483, Barba, P. ORCID: https://orcid.org/0000-0003-1038-5197, Jain, M.D. ORCID: https://orcid.org/0000-0002-7789-1257 and Subklewe, M. ORCID: https://orcid.org/0000-0001-9154-9469
Science Advances 9 (38): eadg3919. 22 September 2023

Cardiovascular health-related quality of life in cancer: a prospective study comparing the ESC HeartQoL and EORTC QLQ-C30 questionnaire.
Anker, M.S., Potthoff, S.K., Lena, A., Porthun, J., Hadzibegovic, S., Evertz, R., Denecke, C., Fröhlich, A.K., Sonntag, F., Regitz-Zagrosek, V., Rosen, S.D., Lyon, A.R., Lüscher, T.F., Spertus, J.A., Anker, S.D., Karakas, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Landmesser, U., Butler, J. and von Haehling, S.
European Journal of Heart Failure 25 (9): 1635-1647. September 2023

Hand grip strength in patients with advanced cancer: a prospective study.
Hadzibegovic, S., Porthun, J., Lena, A., Weinlaänder, P., Lück, L.C., Potthoff, S.K., Rösnick, L., Fröhlich, A.K., Ramer, L.V., Sonntag, F., Wilkenshoff, U., Ahn, J., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mahabadi, A.A., Totzeck, M., Rassaf, T., von Haehling, S., Coats, A.J.S., Anker, S.D., Roeland, E.J., Landmesser, U. and Anker, M.S. ORCID: https://orcid.org/0000-0002-4406-8555
Journal of Cachexia Sarcopenia and Muscle 14 (4): 1682-1694. August 2023

Inferior outcomes of EU versus US patients treated with CD19 CAR-T for relapsed/refractory large B-cell lymphoma: association with differences in tumor burden, systemic inflammation, bridging therapy utilization, and CAR-T product use.
Bücklein, V., Perez, A., Rejeski, K., Iacoboni, G., Jurinovic, V., Holtick, U., Penack, O., Kharboutli, S., Blumenberg, V., Ackermann, J., Frölich, L., Johnson, G., Patel, K., Arciola, B., Mhaskar, R., Wood, A., Schmidt, C., Albanyan, O., Gödel, P., Hoster, E., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mackensen, A., Locke, F., von Bergwelt, M., Barba, P., Subklewe, M. and Jain, M.D.
HemaSphere 7 (8): e907. August 2023

Patient-reported ability to walk 4 m and to wash: New clinical endpoints and predictors of survival in patients with pre-terminal cancer.
Anker, M.S. ORCID: https://orcid.org/0000-0002-4406-8555, Lena, A., Roeland, E.J., Porthun, J., Schmitz, S., Hadzibegovic, S., Sikorski, P., Wilkenshoff, U., Fröhlich, A.K., Ramer, L.V., Rose, M., Eucker, J., Rassaf, T., Totzeck, M., Lehmann, L.H., von Haehling, S., Coats, A.J.S., Friede, T. ORCID: https://orcid.org/0000-0001-5347-7441, Butler, J., Anker, S.D., Riess, H., Landmesser, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Ahn, J.
Journal of Cachexia Sarcopenia and Muscle 14 (4): 1670-1681. August 2023

Personalizing precision medicine: Patients with AML perceptions about treatment decisions.
Grauman, A., Kontro, M., Haller, K., Nier, S., Aakko, S., Lang, K., Zingaretti, C., Meggiolaro, E., De Padova, S., Marconi, G., Martinelli, G., Heckman, C.A., Simonetti, G., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Kihlbom, U.
Patient Education and Counseling 115 : 107883. 5 July 2023

Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised, open-label, multicentre, phase 3 trial.
Döhner, H., Weber, D., Krzykalla, J., Fiedler, W., Kühn, M.W.M., Schroeder, T., Mayer, K., Lübbert, M., Wattad, M., Götze, K., Fransecky, L., Koller, E., Wulf, G., Schleicher, J., Ringhoffer, M., Greil, R., Hertenstein, B., Krauter, J., Martens, U.M., Nachbaur, D., Samra, M.A., Machherndl-Spandl, S., Basara, N., Leis, C., Schrade, A., Kapp-Schwoerer, S., Cocciardi, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Thol, F., Heuser, M., Paschka, P., Gaidzik, V.I., Saadati, M., Benner, A., Schlenk, R.F., Döhner, K. and Ganser, A.
Lancet Haematology 10 (7): e495-e509. July 2023

Risk factors and characteristics influencing humoral response to COVID-19 vaccination in patients after allogeneic stem cell transplantation.
Hütter-Krönke, M.L., Neagoie, A., Blau, I.W., Wais, V., Vuong, L., Gantner, A., Ahn, J., Penack, O., Schnell, J., Nogai, K.A., Eberspächer, B., Saadati, M., Benner, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, H., Bunjes, D. and Sala, E.
Frontiers in Immunology 14 : 1174289. 3 May 2023

Clinical and prognostic relevance of cardiac wasting in patients with advanced cancer.
Lena, A., Wilkenshoff, U., Hadzibegovic, S., Porthun, J., Rösnick, L., Fröhlich, A.K., Zeller, T., Karakas, M., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Ahn, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Riess, H., Rosen, S.D., Lyon, A.R., Lüscher, T.F., Totzeck, M., Rassaf, T., Burkhoff, D., Mehra, M.R., Bax, J.J., Butler, J., Edelmann, F., Haverkamp, W., Anker, S.D., Packer, M., Coats, A.J.S., von Haehling, S., Landmesser, U. and Anker, M.S.
Journal of the American College of Cardiology 81 (16): 1569-1586. 25 April 2023

Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia.
Straube, J. ORCID: https://orcid.org/0000-0002-1748-0659, Eifert, T., Vu, T. ORCID: https://orcid.org/0000-0003-2831-2957, Janardhanan, Y., Haldar, R., von Eyss, B., Cooper, L., Bruedigam, C., Ling, V.Y. ORCID: https://orcid.org/0000-0001-9757-1229, Cooper, E., Patch, A.M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Schnoeder, T.M., Bywater, M., Heidel, F.H. and Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209
Leukemia 37 (4): 741-750. April 2023

Retained functional normal and preleukemic HSCs at diagnosis are associated to good prognosis in DNMT3Amut NPM1mut AMLs.
Donato, E., Correia, N.C., Andresen, C., Karpova, D., Würth, R., Klein, C., Sohn, M., Przybylla, A., Zeisberger, P., Rothfelder, K., Salih, H.R., Bonig, H., Stasik, S., Röllig, C., Dolnik, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Buchholz, F., Thiede, C.D., Hübschmann, D. and Trumpp, A.
Blood Advances 7 (6): 1011-1018. 28 March 2023

Sarcoma patients admitted to the intensive care unit (ICU): predictive relevance of common sepsis and performance parameters.
Striefler, J.K., Binder, P.T., Brandes, F., Rau, D., Wittenberg, S., Kaul, D., Roohani, S., Jarosch, A. ORCID: https://orcid.org/0000-0002-6040-394X, Schäfer, F.M., Öllinger, R. ORCID: https://orcid.org/0000-0002-4499-1673, Märdian, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Eckardt, K.U., Kruse, J. and Flörcken, A.
Cancer Management and Research 15 : 321-334. 27 March 2023

Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends, C.M. ORCID: https://orcid.org/0000-0003-4417-4750, Liman, T.G., Strzelecka, P.M. ORCID: https://orcid.org/0000-0003-0226-6788, Kufner, A., Löwe, P. ORCID: https://orcid.org/0000-0002-6222-5323, Huo, S. ORCID: https://orcid.org/0000-0002-0119-7517, Stein, C.M. ORCID: https://orcid.org/0000-0002-9015-7671, Piper, S.K. ORCID: https://orcid.org/0000-0002-0147-8992, Tilgner, M. ORCID: https://orcid.org/0000-0003-3196-6214, Sperber, P.S. ORCID: https://orcid.org/0000-0002-9534-2374, Dimitriou, S., Heuschmann, P. ORCID: https://orcid.org/0000-0002-2681-3515, Hablesreiter, R., Harms, C. ORCID: https://orcid.org/0000-0002-2063-2860, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Weber, J.E. ORCID: https://orcid.org/0000-0002-1666-6021, Endres, M. ORCID: https://orcid.org/0000-0001-6520-3720 and Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173
Blood 141 (7): 787-799. 16 February 2023

Response to anti-SARS-CoV-2 mRNA vaccines in multiple myeloma and chronic lymphocytic leukemia patients.
Zaleska, J., Kwasnik, P., Paziewska, M., Purkot, Jo., Szabelak, A., Jurek, M., Masny, N., Dziatkiewicz, I., Pronobis-Szczylik, B., Piebiak, A., Szymczyk, A., Jarosz-Chudzik, K., Bolkun, L., Kozlowska, K., Piszcz, J., Subocz, E., Halka, J., Bator, M., Kalicinska, E., Wrobel, T., Usnarska-Zubkiewicz, L., Rybka, J., Deren-Wagemann, I., Szyca-Smieszniak, M., Dybko, J., Hus, I., Pula, B., Cichocka, E., Rymko, M., Zdunczyk, D., Ziarkiewicz, M., Basak, G.W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Giannopoulos, K. ORCID: https://orcid.org/0000-0003-0135-4030
International Journal of Cancer 15 (4): 705-712. 15 February 2023

Single-cell clonal tracking of persistent T-cells in allogeneic hematopoietic stem cell transplantation.
Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Keilholz, L., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Frentsch, M., Blau, I.W., Vuong, L., Lesch, S., Movasshagi, K., Tietze-Stolley, C., Loyal, L., Henze, L., Penack, O., Stervbo, U. ORCID: https://orcid.org/0000-0002-2831-8868, Babel, N., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Wittenbecher, F. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Frontiers in Immunology 14 : 1114368. 10 February 2023

Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.
Mansouri, L., Thorvaldsdottir, B., Sutton, L.A., Karakatsoulis, G., Meggendorfer, M., Parker, H., Nadeu, F., Brieghel, C., Laidou, S., Moia, R., Rossi, D., Catherwood, M., Kotaskova, J., Delgado, J., Rodríguez-Vicente, A.E., Benito, R., Rigolin, G.M., Bonfiglio, S., Scarfo, L., Mattsson, M., Davis, Z., Gogia, A., Rani, L., Baliakas, P., Foroughi-Asl, H., Jylhä, C., Skaftason, A., Rapado, I., Miras, F., Martinez-Lopez, J., de la Serna, J., Rivas, J.M.H., Thornton, P., Larráyoz, M.J., Calasanz, M.J., Fésüs, V., Mátrai, Z., Bödör, C., Smedby, K.E., Espinet, B., Puiggros, A., Gupta, R., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Bosch, F., Tazón-Vega, B., Baran-Marszak, F., Oscier, D., Nguyen-Khac, F., Zenz, T., Terol, M.J., Cuneo, A., Hernández-Sánchez, M., Pospisilova, S., Mills, K., Gaidano, G., Niemann, C.U., Campo, E., Strefford, J.C., Ghia, P., Stamatopoulos, K. and Rosenquist, R.
Leukemia 37 (2): 339-347. February 2023

Immune phenotypes and checkpoint molecule expression of clonally expanded lymph node-infiltrating T cells in classical Hodgkin lymphoma.
Ballhausen, A. ORCID: https://orcid.org/0000-0002-5470-4973, Ben Hamza, A., Welters, C., Dietze, K., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Rahn, H.P. ORCID: https://orcid.org/0000-0002-5233-3937, Hartmann, S., Hansmann, M.L. and Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128
Cancer Immunology Immunotherapy 72 (2): 515-521. February 2023

Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial.
Denkinger, C.M., Janssen, M., Schäkel, U., Gall, J., Leo, A., Stelmach, P., Weber, S.F., Krisam, J., Baumann, L., Stermann, J., Merle, U., Weigand, M.A., Nusshag, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Schrezenmeier, J.F., Bornhäuser, M., Alakel, N., Witzke, O., Wolf, T., Vehreschild, M.J.G.T., Schmiedel, S., Addo, M.M., Herth, F., Kreuter, M., Tepasse, P.R., Hertenstein, B., Hänel, M., Morgner, A., Kiehl, M., Hopfer, O., Wattad, M.A., Schimanski, C.C., Celik, C., Pohle, T., Ruhe, M., Kern, W.V., Schmitt, A., Lorenz, H.M., Souto-Carneiro, M., Gaeddert, M., Halama, N., Meuer, S., Kräusslich, H.G., Müller, B., Schnitzler, P., Parthé, S., Bartenschlager, R., Gronkowski, M., Klemmer, J., Schmitt, M., Dreger, P., Kriegsmann, K., Schlenk, Ri.F. and Müller-Tidow, C.
Nature Cancer 4 (1): 96-107. January 2023

Patterns, predictors and prognostic relevance of high-grade hematotoxicity after temozolomide or temozolomide-lomustine in the CeTeG/NOA-09 trial.
Weller, J. ORCID: https://orcid.org/0000-0001-5818-5392, Schäfer, N., Schaub, C., Tzaridis, T. ORCID: https://orcid.org/0000-0001-9651-1144, Zeyen, T., Schneider, M. ORCID: https://orcid.org/0000-0002-6025-7479, Potthoff, A.L. ORCID: https://orcid.org/0000-0002-5710-6557, Giordano, F.A., Steinbach, J.P., Zeiner, P.S., Kowalski, T., Sabel, M., Hau, P., Krex, D., Grauer, O., Goldbrunner, R., Schnell, O., Tabatabai, G. ORCID: https://orcid.org/0000-0002-3542-8782, Ringel, F. ORCID: https://orcid.org/0000-0003-3132-7543, Schmidt-Graf, F., Brehmer, S., Tonn, J.C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Vajkoczy, P., Glas, M., Vatter, H., Herrlinger, U. and Seidel, C.
Journal of Neuro-Oncology 161 (1): 147-153. January 2023

Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia.
Ling, V.Y. ORCID: https://orcid.org/0000-0001-9757-1229, Straube, J. ORCID: https://orcid.org/0000-0002-1748-0659, Godfrey, W., Haldar, R., Janardhanan, Y., Cooper, L., Bruedigam, C., Cooper, E., Tavakoli Shirazi, P., Jacquelin, S. ORCID: https://orcid.org/0000-0001-5087-3641, Tey, S.K. ORCID: https://orcid.org/0000-0001-9567-382X, Baell, J., Huang, F. ORCID: https://orcid.org/0000-0002-5290-2490, Jin, J., Zhao, Y., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Bywater, M.J. and Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209
Leukemia 37 (1): 143-153. January 2023

Relapse of NPM1-mutated AML with extramedullary manifestation 17 years after allogeneic hematopoietic stem cell transplantation.
Braune, J. ORCID: https://orcid.org/0000-0003-2026-2641, Rieger, K., Blau, O. ORCID: https://orcid.org/0000-0002-4304-5079, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Krönke, J.
Case Reports in Hematology 2022 : 3317936. 28 December 2022

TIGIT blockade repolarizes AML-associated TIGIT(+) M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis.
Brauneck, F. ORCID: https://orcid.org/0000-0002-0026-3658, Fischer, B., Witt, M., Muschhammer, J., Oelrich, J., da Costa Avelar, P.H. ORCID: https://orcid.org/0000-0002-0347-7002, Tsoka, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Seubert, E., Smit, D.J. ORCID: https://orcid.org/0000-0002-3190-9511, Bokemeyer, C., Ackermann, C., Wellbrock, J., Haag, F. and Fiedler, W.
Journal for ImmunoTherapy of Cancer 10 (12): e004794. 22 December 2022

Immune phenotypes and target antigens of clonally expanded bone marrow T cells in treatment-naïve multiple myeloma.
Welters, C. ORCID: https://orcid.org/0000-0002-3098-9003, Lammoglia Cobo, M.F. ORCID: https://orcid.org/0000-0002-0369-0364, Stein, C.A. ORCID: https://orcid.org/0000-0002-7892-8007, Hsu, M.T. ORCID: https://orcid.org/0000-0002-5862-4305, Ben Hamza, A. ORCID: https://orcid.org/0000-0003-3021-7406, Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207, Chen, X. ORCID: https://orcid.org/0000-0002-5614-1406, Buccitelli, C. ORCID: https://orcid.org/0000-0001-5865-4961, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Dietze, K. ORCID: https://orcid.org/0000-0002-8329-8329, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Moosmann, A. ORCID: https://orcid.org/0000-0001-8044-5146, Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Gerbitz, A. ORCID: https://orcid.org/0000-0002-0105-2086, Strobel, J. ORCID: https://orcid.org/0000-0002-1117-0350, Hackstein, H. ORCID: https://orcid.org/0000-0001-9722-8180, Rahn, H.P. ORCID: https://orcid.org/0000-0002-5233-3937, Dornmair, K. ORCID: https://orcid.org/0000-0003-0342-5373, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128
Cancer Immunology Research 10 (11): 1407-1419. 1 November 2022

Widely applicable, extended flow cytometric stem cell enumeration panel for quality control of advanced cellular products.
Haussmann, K., Streitz, M., Takvorian, A., Grund, J., Skenderi, Z., Tietze-Bürger, C., Movassaghi, K., Künkele, A., Blum, A. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Scientific Reports 12 (1): 17995. 26 October 2022

Building a Healthcare Alliance for Resourceful Medicine Offensive Against Neoplasms in hematologY added value framework for hematologic malignancies: a comparative analysis of existing tools.
Cerisoli, F., Ali, F., Bereczky, T., Bolaños, N., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Dhanasiri, S., Gallagher, J., Pérez, S.G., Geissler, J., Guillevic, Y., Harrison, K., Naoum, A., Portulano, C., Rodríguez Vicente, A.E., Schulze-Rath, R., Gómez, G.Y., Sanz, G. and Hernández Rivas, J.M.
Value in Health 25 (10): 1760-1767. October 2022

Midostaurin plus intensive chemotherapy for younger and older patients with AML and FLT3 internal tandem duplications.
Döhner, H., Weber, D., Krzykalla, J., Fiedler, W., Wulf, G.G., Salih, H.R., Lübbert, M., Kühn, M., Schroeder, T., Salwender, H., Götze, K.S., Westermann, J., Fransecky, L., Mayer, K., Hertenstein, B., Ringhoffer, M., Tischler, H.J., Machherndl-Spandl, S., Schrade, A., Paschka, P., Gaidzik, V.I., Theis, F., Thol, F.R., Heuser, M., Schlenk, R.F., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Saadati, M., Benner, A., Larson, R.A., Stone, R.M., Döhner, K. and Ganser, A.
Blood Advances 6 (18): 5345-5355. 27 September 2022

Comorbidities rather than older age define outcome in adult patients with tumors of the Ewing sarcoma family.
Striefler, J.K. ORCID: https://orcid.org/0000-0002-0612-3023, Schmiester, M., Brandes, F., Dörr, A., Pahl, S., Kaul, D., Rau, D., Dobrindt, E.M., Koulaxouzidis, G., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Märdian, S. and Flörcken, A.
Cancer Medicine 11 (17): 3213-3225. September 2022

Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.
Jahn, N., Jahn, E., Saadati, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Larson, R.A. ORCID: https://orcid.org/0000-0001-9168-3203, Ottone, T., Amadori, S., Prior, T.W., Brandwein, J.M., Appelbaum, F.R., Medeiros, B.C. ORCID: https://orcid.org/0000-0001-6972-8137, Tallman, M.S., Ehninger, G., Heuser, M. ORCID: https://orcid.org/0000-0001-5318-9044, Ganser, A., Pallaud, C., Gathmann, I., Krzykalla, J., Benner, A., Bloomfield, C.D. ORCID: https://orcid.org/0000-0001-5465-7591, Thiede, C. ORCID: https://orcid.org/0000-0003-1241-2048, Stone, R.M. ORCID: https://orcid.org/0000-0002-7526-2633, Döhner, H. and Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862
Leukemia 36 (9): 2218-2227. September 2022

Concomitant cytotoxic effector differentiation of CD4(+) and CD8(+) T cells in response to EBV-Infected B cells.
Tamura, Y., Yamane, K., Kawano, Y., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Wirtz, T. ORCID: https://orcid.org/0009-0005-5677-9804, Weber, T. ORCID: https://orcid.org/0000-0003-2079-842X, Sander, S. ORCID: https://orcid.org/0000-0003-4645-3366, Ohki, S., Kitajima, Y. ORCID: https://orcid.org/0000-0001-6277-5918, Okada, S. ORCID: https://orcid.org/0000-0002-4622-5657, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Yasuda, T. ORCID: https://orcid.org/0000-0001-9997-6852
Cancers 14 (17): 4118. 25 August 2022

Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia.
Zhai, Y., Singh, P., Dolnik, A., Brazda, P., Atlasy, N., Del Gaudio, N., Döhner, K., Döhner, H., Minucci, S., Martens, J., Altucci, L., Megchelenbrink, W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Stunnenberg, H.G.
Molecular Cancer 21 (1): 166. 19 August 2022

The landscape of genetic aberrations in myxofibrosarcoma.
Takeuchi, Y., Yoshida, K., Halik, A., Kunitz, A., Suzuki, H., Kakiuchi, N., Shiozawa, Y., Yokoyama, A., Inoue, Y., Hirano, T., Yoshizato, T., Aoki, K., Fujii, Y., Nannya, Y., Makishima, H., Pfitzner, B.M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Hirata, M., Jinnouchi, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Okamoto, T., Haga, H., Ogawa, S. and Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173
International Journal of Cancer 151 (4): 565-577. 15 August 2022

Unified classification and risk-stratification in Acute Myeloid Leukemia.
Tazi, Y. ORCID: https://orcid.org/0000-0002-1595-9631, Arango-Ossa, J.E., Zhou, Y., Bernard, E. ORCID: https://orcid.org/0000-0002-2057-7187, Thomas, I., Gilkes, A., Freeman, S. ORCID: https://orcid.org/0000-0003-1869-180X, Pradat, Y. ORCID: https://orcid.org/0000-0002-4647-5779, Johnson, S.J., Hills, R., Dillon, R., Levine, M.F. ORCID: https://orcid.org/0000-0001-5156-9086, Leongamornlert, D. ORCID: https://orcid.org/0000-0002-3486-3168, Butler, A., Ganser, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862, Ottmann, O., Adams, R. ORCID: https://orcid.org/0000-0003-3915-7243, Döhner, H. ORCID: https://orcid.org/0000-0003-2116-5536, Campbell, P.J. ORCID: https://orcid.org/0000-0002-3921-0510, Burnett, A.K. ORCID: https://orcid.org/0000-0003-1734-5817, Dennis, M., Russell, N.H., Devlin, S.M. ORCID: https://orcid.org/0000-0002-6801-720X, Huntly, B.J.P. ORCID: https://orcid.org/0000-0003-0312-161X and Papaemmanuil, E. ORCID: https://orcid.org/0000-0003-1709-8983
Nature Communications 13 (1): 4622. 8 August 2022

Acute myeloid leukemia: negative prognostic impact of early blast persistence can be in part overcome by a later remission prior to post-induction therapy.
Ihlow, J., Gross, S., Busack, L., Flörcken, A., Jesse, J., Schwarz, M., Neuendorff, N.R., von Brünneck, A.C., Anagnostopoulos, I., Türkmen, S., Blau, I.W., Burmeister, T., Horst, D., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Westermann, J.
Haematologica 107 (8): 1773-1785. August 2022

Long-term observation of the frequency of secondary colorectal cancer and other malignancies in tyrosine kinase inhibitor treated chronic myeloid leukemia patients and controls.
Winkelmann, N., Schwarz, M., Hildebrandt, B., Henke, O., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Stintzing, S. and le Coutre, P. ORCID: https://orcid.org/0000-0003-4532-1097
eJHaem: The Official Journal of the British Society for Haematology 3 (3): 949-953. August 2022

Rapid single-cell identification of Epstein-Barr virus-specific T-cell receptors for cellular therapy.
Lammoglia Cobo, M.F. ORCID: https://orcid.org/0000-0002-0369-0364, Welters, C. ORCID: https://orcid.org/0000-0002-3098-9003, Rosenberger, L., Leisegang, M. ORCID: https://orcid.org/0000-0003-3692-7142, Dietze, K., Pircher, C., Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207, Gary, R., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Takvorian, A., Moosmann, A., Dornmair, K. ORCID: https://orcid.org/0000-0003-0342-5373, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Kammertöns, T. ORCID: https://orcid.org/0000-0003-3309-5141, Gerbitz, A. ORCID: https://orcid.org/0000-0002-0105-2086 and Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128
Cytotherapy 24 (8): 818-826. August 2022

The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells.
Viñado, A.C., Calvo, I.A. ORCID: https://orcid.org/0000-0001-6619-4571, Cenzano, I. ORCID: https://orcid.org/0000-0002-9030-3069, Olaverri, D. ORCID: https://orcid.org/0000-0003-1740-6616, Cocera, M. ORCID: https://orcid.org/0000-0002-5679-1206, San Martin-Uriz, P., Romero, J.P., Vilas-Zornoza, A., Vera, L., Gomez-Cebrian, N. ORCID: https://orcid.org/0000-0001-5604-9223, Puchades-Carrasco, L. ORCID: https://orcid.org/0000-0003-0340-7458, Lisi-Vega, L.E. ORCID: https://orcid.org/0000-0001-7664-5356, Apaolaza, I. ORCID: https://orcid.org/0000-0002-8961-4513, Valera, P., Guruceaga, E. ORCID: https://orcid.org/0000-0003-0547-681X, Granero-Molto, F. ORCID: https://orcid.org/0000-0003-4817-5232, Ripalda-Cemborain, P. ORCID: https://orcid.org/0000-0001-8425-3563, Luck, T.J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Planes, F.J. ORCID: https://orcid.org/0000-0003-1155-3105, Rifon, J.J., Méndez-Ferrer, S. ORCID: https://orcid.org/0000-0002-9805-9988, Yusuf, R.Z., Pardo-Saganta, A., Prosper, F. ORCID: https://orcid.org/0000-0001-6115-8790 and Saez, B. ORCID: https://orcid.org/0000-0001-7908-7089
Leukemia 36 (8): 1969-1979. August 2022

The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
Grasedieck, S., Cabantog, A., MacPhee, L., Im, J., Ruess, C., Demir, B., Sperb, N., Rücker, F.G., Döhner, K., Herold, T., Pollack, J.R., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Rouhi, A. and Kuchenbauer, F.
Haematologica 107 (8): 1758-1772. August 2022

Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma.
Schmiester, M., Maier, R., Riedel, R., Durek, P., Frentsch, M., Kolling, S., Mashreghi, M.F., Jenq, R., Zhang, L., Peterson, C.B. ORCID: https://orcid.org/0000-0003-3316-0468, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Chang, H.D. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Gut Microbes 14 (1): e2081475. 29 May 2022

Paired donor and recipient immunophenotyping in allogeneic hematopoietic stem cell transplantation: a cellular network approach.
Wittenbecher, F., Lesch, S., Kolling, S., Blau, I.W., Vuong, L., Borchert, F., Movasshagi, K., Tietze-Bürger, C., Penack, O., Ahn, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Frentsch, M. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Frontiers in Immunology 13 : 874499. 23 May 2022

The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL.
Rejeski, K. ORCID: https://orcid.org/0000-0003-3905-0251, Perez, A., Iacoboni, G., Penack, O., Bücklein, V., Jentzsch, L., Mougiakakos, D., Johnson, G., Arciola, B., Carpio, C., Blumenberg, V., Hoster, E., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Locke, F.L., von Bergwelt-Baildon, M., Mackensen, A., Bethge, W., Barba, P., Jain, M.D. ORCID: https://orcid.org/0000-0002-7789-1257 and Subklewe, M.
Journal for ImmunoTherapy of Cancer 10 (5): e004475. 17 May 2022

Antigen presentation safeguards the integrity of the hematopoietic stem cell pool.
Hernández-Malmierca, P., Vonficht, D. ORCID: https://orcid.org/0000-0002-5579-7083, Schnell, A., Uckelmann, H.J., Bollhagen, A., Mahmoud, M.A.A., Landua, S.L., van der Salm, E., Trautmann, C., Raffel, S., Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Lutz, R., Ghosh, M., Renders, S., Correia, N., Donato, E., Dixon, K.O., Hirche, C., Andresen, C., Robens, Cl., Werner, P.S., Boch, T., Eisel, D., Osen, W., Pilz, F., Przybylla, A., Klein, C., Buchholz, F., Milsom, M.D., Essers, M.A.G., Eichmüller, S.B., Hofmann, W.K., Nowak, D., Hübschmann, D., Hundemer, M., Thiede, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Müller-Tidow, C., Armstrong, S.A., Trumpp, A., Kuchroo, V.K. and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Cell Stem Cell 29 (5): 760-775. 5 May 2022

Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade.
Kofla, G., Radecke, C., Frentsch, M., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Stintzing, S., Riess, H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
OncoImmunology 11 (1): 2068109. 25 April 2022

EASIX and severe endothelial complications after CD19-directed CAR-T Cell therapy-a cohort study.
Korell, F., Penack, O., Mattie, M., Schreck, N., Benner, A., Krzykalla, J., Wang, Z., Schmitt, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Müller-Tidow, C., Dreger, P. and Luft, T.
Frontiers in Immunology 13 : 877477. 8 April 2022

FIRE-9 - PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer.
Raschzok, N., Stintzing, S., Heinemann, V., Rauch, G., Ricke, J., Guckenberger, M., Kurreck, A., Alig, A.H.S., Stahler, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Schmelzle, M., Schöning, W., Lurje, G., Krenzien, F., Haase, O., Rau, B., Gebauer, B., Sauer, I.M., Pratschke, J. and Modest, D.P.
BMC Cancer 22 (1): 359. 2 April 2022

Managing hematological cancer patients during the COVID-19 pandemic: an ESMO-EHA interdisciplinary expert consensus.
Buske, C., Dreyling, M., Alvarez-Larrán, A., Apperley, J., Arcaini, L., Besson, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Corradini, P., Della Porta, M.G., Dimopoulos, M., D’Sa, S., Eich, H.T., Foà, R., Ghia, P., Gomes da Silva, M., Gribben, J., Hajek, R., Harrison, C., Heuser, M., Kiesewetter, B., Kiladjian, J.J., Kröger, N., Moreau, P., Passweg, J.R., Peyvandi, F., Rea, D., Ribera, J.M., Robak, T., San-Miguel, J.F., Santini, V., Sanz, G., Sonneveld, P., von Lilienfeld-Toal, M., Wendtner, C., Pentheroudakis, G. and Passamonti, F.
ESMO Open 7 (2): 100403. April 2022

Modeling clonal hematopoiesis in umbilical cord blood cells by CRISPR/Cas9.
Christen, F., Hablesreiter, R., Hoyer, K., Hennch, C. ORCID: https://orcid.org/0000-0003-4104-5531, Maluck-Böttcher, A., Segler, A., Madadi, A., Frick, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Briest, F. ORCID: https://orcid.org/0000-0001-5969-9467 and Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173
Leukemia 36 (4): 1102-1110. April 2022

Simultaneous genetic ablation of PD-1, LAG-3, and TIM-3 in CD8 T cells delays tumor growth and improves survival outcome.
Ciraolo, E. ORCID: https://orcid.org/0000-0002-5601-1695, Althoff, S., Ruß, J., Rosnev, S. ORCID: https://orcid.org/0000-0003-0256-7038, Butze, M., Pühl, M., Frentsch, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
International Journal of Molecular Sciences 23 (6): 3207. 16 March 2022

Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
Arends, C.M., Dimitriou, S., Stahler, A. ORCID: https://orcid.org/0000-0003-1041-0137, Hablesreiter, R., Strzelecka, P.M. ORCID: https://orcid.org/0000-0003-0226-6788, Stein, C.M. ORCID: https://orcid.org/0000-0002-9015-7671, Tilgner, M. ORCID: https://orcid.org/0000-0003-3196-6214, Saiki, R., Ogawa, S. ORCID: https://orcid.org/0000-0002-7778-5374, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Modest, D.P., Stintzing, S. ORCID: https://orcid.org/0000-0002-3297-5801, Heinemann, V. and Damm, F.
Blood 139 (10): 1593-1597. 10 March 2022

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng, Y.L.D. ORCID: https://orcid.org/0000-0001-7959-454X, Ramberger, E. ORCID: https://orcid.org/0000-0003-2760-2696, Bohl, S.R., Dolnik, A., Steinebach, C. ORCID: https://orcid.org/0000-0001-5638-1955, Conrad, T., Müller, S., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Kull, M., Haji, M., Gütschow, M., Döhner, H., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X and Krönke, J. ORCID: https://orcid.org/0000-0002-4649-0506
Nature Communications 13 (1): 1009. 23 February 2022

PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder, T.M., Schwarzer, A., Jayavelu, A.K., Hsu, C.J., Kirkpatrick, J. ORCID: https://orcid.org/0000-0001-9291-7294, Döhner, K., Perner, F., Eifert, T., Huber, N., Arreba-Tutusaus, P., Dolnik, A., Assi, S.A. ORCID: https://orcid.org/0000-0001-5634-1347, Nafria, M. ORCID: https://orcid.org/0000-0002-5329-7966, Jiang, L., Dai, Y.T. ORCID: https://orcid.org/0000-0001-8275-2115, Chen, Z., Chen, S.J., Kellaway, S.G. ORCID: https://orcid.org/0000-0002-4011-7460, Ptasinska, A., Ng, E.S. ORCID: https://orcid.org/0000-0002-7970-8129, Stanley, E.G., Elefanty, A.G. ORCID: https://orcid.org/0000-0001-6448-8314, Buschbeck, M., Bierhoff, H., Brodt, S. ORCID: https://orcid.org/0000-0003-1286-8766, Matziolis, G., Fischer, K.D., Hochhaus, A., Chen, C.W. ORCID: https://orcid.org/0000-0002-8737-6830, Heidenreich, O. ORCID: https://orcid.org/0000-0001-5404-6483, Mann, M., Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Ori, A. ORCID: https://orcid.org/0000-0002-3046-0871, von Eyss, B. ORCID: https://orcid.org/0000-0002-4731-6841, Bonifer, C. and Heidel, F. ORCID: https://orcid.org/0000-0003-2438-1955
Blood 139 (7): 1080-1097. 17 February 2022

Acute left ventricular insufficiency in a Burkitt Lymphoma patient with myocardial involvement and extensive local tumor cell lysis: a case report.
Schmiester, M. ORCID: https://orcid.org/0000-0002-8713-572X, Tranter, E., Lorusso, A., Blaschke, F. ORCID: https://orcid.org/0000-0001-7193-0318, Geisel, D., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Damm, F. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
BMC Cardiovascular Disorders 22 (1): 31. 4 February 2022

Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S. ORCID: https://orcid.org/0000-0002-0736-6019, Bittner, A. ORCID: https://orcid.org/0000-0001-6434-0950, Frick, M., Kase, J., Hoffmann, J., Trenker, C., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bogner, C., Hüttmann, A., Dürig, J., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Marks, R., Krohn, U., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Leukemia & Lymphoma 63 (1): 84-92. January 2022

Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.
Rücker, F.G., Du, L., Luck, T.J., Benner, A. ORCID: https://orcid.org/0000-0002-7238-6956, Krzykalla, J., Gathmann, I., Voso, M.T. ORCID: https://orcid.org/0000-0002-6164-4761, Amadori, S., Prior, T.W., Brandwein, J.M., Appelbaum, F.R., Medeiros, B.C. ORCID: https://orcid.org/0000-0001-6972-8137, Tallman, M.S., Savoie, L., Sierra, J., Pallaud, C., Sanz, M.A. ORCID: https://orcid.org/0000-0003-1489-1177, Jansen, J.H., Niederwieser, D. ORCID: https://orcid.org/0000-0002-4737-1103, Fischer, T., Ehninger, G., Heuser, M. ORCID: https://orcid.org/0000-0001-5318-9044, Ganser, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Larson, R.A. ORCID: https://orcid.org/0000-0001-9168-3203, Bloomfield, C.D. ORCID: https://orcid.org/0000-0001-5465-7591, Stone, R.M., Döhner, H., Thiede, C. ORCID: https://orcid.org/0000-0003-1241-2048 and Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862
Leukemia 36 (1): 90-99. January 2022

Survey of long-term experiences of sperm cryopreservation in oncological and non-oncological patients: usage and reproductive outcomes of a large monocentric cohort.
Lackamp, N., Wilkemeyer, I., Jelas, I., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Stintzing, S. and le Coutre, P.
Frontiers in Oncology 11 : 772809. 5 November 2021

Netboost: boosting-supported network analysis improves high-dimensional omics prediction in acute myeloid leukemia and Huntington's disease.
Schlosser, P. ORCID: https://orcid.org/0000-0002-8460-0462, Knaus, J. ORCID: https://orcid.org/0000-0002-7470-3791, Schmutz, M. ORCID: https://orcid.org/0000-0002-7453-7260, Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862, Plass, C. ORCID: https://orcid.org/0000-0003-2554-3952, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Claus, R. ORCID: https://orcid.org/0000-0003-2617-8766, Binder, H. ORCID: https://orcid.org/0000-0002-5666-8662, Lübbert, M. and Schumacher, M. ORCID: https://orcid.org/0000-0002-5037-0099
IEEE/ACM Transactions on Computational Biology and Bioinformatics 18 (6): 2635-2648. 1 November 2021

Survivin’ acute myeloid leukaemia - a personalised target for inv(16) patients.
Greiner, J. ORCID: https://orcid.org/0000-0003-1256-173X, Brown, E., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Hills, R.K., Morris, V., Döhner, H., Mills, K.I. ORCID: https://orcid.org/0000-0002-6362-4481 and Guinn, B.A. ORCID: https://orcid.org/0000-0003-0639-4541
International Journal of Molecular Sciences 22 (19): 10482. 1 October 2021

Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.
Bloehdorn, J. ORCID: https://orcid.org/0000-0003-1433-9702, Braun, A. ORCID: https://orcid.org/0000-0003-0925-5598, Taylor-Weiner, A., Jebaraj, B.M.C., Robrecht, S., Krzykalla, J., Pan, H., Giza, A., Akylzhanova, G., Holzmann, K., Scheffold, A., Johnston, H.E., Yeh, R.F., Klymenko, T., Tausch, E., Eichhorst, B., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Fischer, K., Weisser, M., Robak, T. ORCID: https://orcid.org/0000-0002-3411-6357, Schneider, C., Gribben, J. ORCID: https://orcid.org/0000-0002-8505-7430, Dahal, L.N. ORCID: https://orcid.org/0000-0001-8390-6593, Carter, M.J., Elemento, O. ORCID: https://orcid.org/0000-0002-8061-9617, Landau, D.A. ORCID: https://orcid.org/0000-0003-2346-9541, Neuberg, D.S. ORCID: https://orcid.org/0000-0003-2566-3145, Cragg, M.S., Benner, A. ORCID: https://orcid.org/0000-0002-7238-6956, Hallek, M., Wu, C.J. ORCID: https://orcid.org/0000-0002-3348-5054, Döhner, H., Stilgenbauer, S. and Mertens, D.
Nature Communications 12 (1): 5395. 13 September 2021

58/w mit zunehmender psychomotorischer Verlangsamung und Zephalgien [58/f with increasing psychomotor retardation and headache].
Onken, J.S. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Onkologe 27 : 79-84. September 2021

CD4+ T cell dependent B cell recovery and function after autologous hematopoietic stem cell transplantation.
Heck, C., Steiner, S., Kaebisch, E.M., Frentsch, M., Wittenbecher, F., Scheibenbogen, C., Hanitsch, L.G., Nogai, A., le Coutre, P., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Blau, I.W. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Frontiers in Immunology 12 : 736137. September 2021

COVID19-associated cardiomyocyte dysfunction, arrhythmias and the effect of Canakinumab.
Dimai, S., Semmler, L., Prabhu, A., Stachelscheid, H. ORCID: https://orcid.org/0000-0002-9283-4605, Huettemeister, J., Klaucke, S.C., Lacour, P., Blaschke, F. ORCID: https://orcid.org/0000-0001-7193-0318, Kruse, J., Parwani, A., Boldt, L.H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Pieske, B.M. ORCID: https://orcid.org/0000-0002-6466-5306, Heinzel, F.R. and Hohendanner, F. ORCID: https://orcid.org/0000-0002-0194-4615
PLoS ONE 16 (8): e0255976. 19 August 2021

A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3.
Halatsch, M.E., Kast, R.E., Karpel-Massler, G., Mayer, B., Zolk, O., Schmitz, B., Scheuerle, A., Maier, L., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mayer-Steinacker, R., Schmidt, C., Zeiler, K., Elshaer, Z., Panther, P., Schmelzle, B., Hallmen, A., Dwucet, A., Siegelin, M.D., Westhoff, M.A., Beckers, K., Bouche, G. and Heiland, T.
Neuro-Oncology Advances 3 (1): vdab075. 7 August 2021

Polatuzumab vedotin as a salvage and bridging treatment in relapsed or refractory large B-cell lymphomas.
Liebers, N., Duell, J., Fitzgerald, D. ORCID: https://orcid.org/0000-0003-4927-7484, Kerkhoff, A., Noerenberg, D., Kaebisch, E. ORCID: https://orcid.org/0000-0001-7752-4126, Acker, F. ORCID: https://orcid.org/0000-0002-6207-0237, Fuhrmann, S. ORCID: https://orcid.org/0000-0002-7785-2565, Leng, C., Welslau, M., Chemnitz, J., Middeke, J.M., Weber, T. ORCID: https://orcid.org/0000-0002-8724-9348, Holtick, U., Trappe, R., Pfannes, R., Liersch, R., Spoer, C., Fuxius, S., Gebauer, N., Caillé, L., Geer, T., Koenecke, C. ORCID: https://orcid.org/0000-0001-7025-1735, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Claus, R. ORCID: https://orcid.org/0000-0003-2617-8766, Mougiakakos, D., Mayer, S., Huettmann, A. ORCID: https://orcid.org/0000-0003-2230-3873, Pott, C., Trummer, A., Wulf, G., Brunnberg, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Hess, G., Mueller-Tidow, C., Glass, B., Lenz, G., Dreger, P. and Dietrich, S.
Blood Advances 5 (13): 2707-2716. 13 July 2021

Early bilirubinemia after allogeneic stem cell transplantation - an endothelial complication.
Dai, H., Penack, O., Radujkovic, A., Schult, D., Majer-Lauterbach, J., Blau, I.W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Jiang, S., Müller-Tidow, C., Dreger, P. ORCID: https://orcid.org/0000-0002-7429-8570 and Luft, T.
Bone Marrow Transplantation 56 (7): 1573-1583. July 2021

Long-term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges.
Herda, S., Heimann, A., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Ciraolo, E. ORCID: https://orcid.org/0000-0002-5601-1695, Althoff, S., Ruß, J., Grunert, C. ORCID: https://orcid.org/0000-0001-8376-8629, Busse, A. ORCID: https://orcid.org/0000-0002-3470-6947, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Pezzutto, A. ORCID: https://orcid.org/0000-0002-3246-4470, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632 and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
International Journal of Cancer 148 (12): 3097-3110. 15 June 2021

Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.
Schmalbrock, L.K. ORCID: https://orcid.org/0000-0002-6080-6175, Dolnik, A., Cocciardi, S., Sträng, E., Theis, F., Jahn, N., Panina, E., Blätte, T.J., Herzig, J.K., Skambraks, S., Rücker, F.G., Gaidzik, V.I., Paschka, P., Fiedler, W., Salih, H.R., Wulf, G.G., Schroeder, T., Lübbert, M., Schlenk, R.F., Thol, F., Heuser, M., Larson, R.A., Ganser, A., Stunnenberg, H.G., Minucci, S., Stone, R.M., Bloomfield, C.D., Döhner, H., Döhner, K. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Blood 137 (22): 3093-3104. 3 June 2021

Comprehensive CRISPR-Cas9 screens identify genetic determinants of drug responsiveness in multiple myeloma.
Bohl, S.R., Schmalbrock, L.K. ORCID: https://orcid.org/0000-0002-6080-6175, Bauhuf, I., Meyer, T., Dolnik, A., Szyska, M. ORCID: https://orcid.org/0000-0002-4213-4600, Blätte, T.J. ORCID: https://orcid.org/0000-0002-9859-1261, Knödler, S., Röhner, L. ORCID: https://orcid.org/0000-0003-1474-8039, Miller, D., Kull, M., Langer, C., Döhner, H., Letai, A., Damm, F., Heckl, D., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Krönke, J. ORCID: https://orcid.org/0000-0002-4649-0506
Blood Advances 5 (9): 2391-2402. 11 May 2021

Posttransplantation MRD monitoring in patients with AML by next-generation sequencing using DTA and non-DTA mutations.
Heuser, M. ORCID: https://orcid.org/0000-0001-5318-9044, Heida, B., Büttner, K., Wienecke, C.P., Teich, K., Funke, C., Brandes, M., Klement, P., Liebich, A., Wichmann, M., Neziri, B., Chaturvedi, A., Kloos, A., Mintzas, K., Gaidzik, V.I., Paschka, P., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Fiedler, W., Heim, A., Puppe, W., Krauter, J., Döhner, K., Döhner, H., Ganser, A. ORCID: https://orcid.org/0000-0003-3510-4304, Stadler, M., Hambach, L., Gabdoulline, R. and Thol, F.
Blood Advances 5 (9): 2294-2304. 11 May 2021

Clinical outcome of older adults with acute myeloid leukemia: an analysis of a large tertiary referral center over two decades.
Ihlow, J., Gross, S., Neuendorff, N.R., Busack, L., Herneth, A., Singh, A., Schwarz, M., Flörcken, A., Anagnostopoulos, I., Türkmen, S., Burmeister, T., Blau, I.W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Westermann, J.
Journal of Geriatric Oncology 12 (4): 540-549. May 2021

DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia.
Giacopelli, B., Wang, M., Cleary, A., Wu, Y.Z., Schultz, A.R., Schmutz, M., Blachly, J.S., Eisfeld, A.K., Mundy-Bosse, B., Vosberg, S., Greif, P.A., Claus, R., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Garzon, R., Coombes, K.R., Bloomfield, C.D., Druker, B.J., Tyner, J.W., Byrd, J.C. and Oakes, C.C.
Genome Research 31 (5): 747-761. May 2021

A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: results from the CONKO-005 trial.
Hoyer, K., Hablesreiter, R., Inoue, Y., Yoshida, K., Briest, F., Christen, F., Kakiuchi, N., Yoshizato, T., Shiozawa, Y., Shiraishi, Y., Striefler, J.K., Bischoff, S., Lohneis, P., Putter, H., Blau, O., Keilholz, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Pelzer, U., Hummel, M., Riess, H., Ogawa, S., Sinn, M. and Damm, F.
EBioMedicine 66 : 103327. April 2021

Deregulated expression of circular RNAs in acute myeloid leukemia.
Lux, S. ORCID: https://orcid.org/0000-0003-3826-5242, Blätte, T.J. ORCID: https://orcid.org/0000-0002-9859-1261, Gillissen, B., Richter, A., Cocciardi, S., Skambraks, S., Schwarz, K., Schrezenmeier, H., Döhner, H., Döhner, K., Dolnik, A. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Blood Advances 5 (5): 1490-1503. 9 March 2021

B cell depletion and signs of sepsis-acquired immunodeficiency in bone marrow and spleen of COVID-19 deceased.
Ihlow, J. ORCID: https://orcid.org/0000-0001-5484-1321, Michaelis, E., Greuel, S., Heynol, V., Lehmann, A., Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Meinhardt, J., Miller, F., Herbst, H., Corman, V.M., Westermann, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Horst, D., von Brünneck, A.C. and Elezkurtaj, S.
International Journal of Infectious Diseases 103 : 628-635. February 2021

Impact of a specialised palliative care intervention in patients with advanced soft tissue sarcoma - a single-centre retrospective analysis.
Brandes, F., Striefler, J.K., Dörr, A., Schmiester, M., Märdian, S., Koulaxouzidis, G., Kaul, D., Behzadi, A., Thuss-Patience, P., Ahn, J., Pelzer, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Flörcken, A.
BMC Palliative Care 20 (1): 16. 14 January 2021

TFE3 activation in a TSC1-altered malignant PEComa: challenging the dichotomy of the underlying pathogenic mechanisms.
Schmiester, M., Dolnik, A., Kornak, U., Pfitzner, B., Hummel, M., Treue, D., Hartmann, A., Agaimy, A., Weyerer, V., Lekaj, A., Brakemeier, S., Peters, R., Öllinger, R., Märdian, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Striefler, J.K. and Flörcken, A.
Journal of Pathology Clinical Research 7 (1): 3-9. January 2021

Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial.
Kapp-Schwoerer, S., Weber, D., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Krönke, J., Theis, F., Rücker, F.G., Teleanu, M.V., Panina, E., Jahn, N., Herzig, J., Kubanek, L., Schrade, A., Göhring, G., Fiedler, W., Kindler, T, Schroeder, T., Mayer, K.T., Lübbert, M., Wattad, M., Götze, K.S. ORCID: https://orcid.org/0000-0002-6276-8002, Horst, H.A., Koller, E., Wulf, G. ORCID: https://orcid.org/0000-0002-7669-3785, Schleicher, J., Bentz, M., Krauter, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Krzykalla, J., Benner, A. ORCID: https://orcid.org/0000-0002-7238-6956, Schlenk, R.F. ORCID: https://orcid.org/0000-0003-2215-2059, Thol, F., Heuser, M., Ganser, A., Döhner, H ORCID: https://orcid.org/0000-0003-2116-5536 and Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862
Blood 136 (26): 3041-3050. 24 December 2020

Genomic heterogeneity in core-binding factor acute myeloid leukemia and its clinical implication.
Jahn, N., Terzer, T. ORCID: https://orcid.org/0000-0003-2495-3589, Sträng, E., Dolnik, A., Cocciardi, S., Panina, E., Corbacioglu, A., Herzig, J., Weber, D., Schrade, A., Götze, K. ORCID: https://orcid.org/0000-0002-6276-8002, Schröder, T., Lübbert, M., Wellnitz, D., Koller, E., Schlenk, R.F. ORCID: https://orcid.org/0000-0003-2215-2059, Gaidzik, V.I., Paschka, P., Rücker, F.G., Heuser, M., Thol, F., Ganser, A., Benner, A. ORCID: https://orcid.org/0000-0002-7238-6956, Döhner, H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Döhner, K.
Blood Advances 4 (24): 6342-6352. 22 December 2020

Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.
Jayavelu, A.K., Schnöder, T.M., Perner, F., Herzog, C., Meiler, A. ORCID: https://orcid.org/0000-0003-0012-7952, Krishnamoorthy, G. ORCID: https://orcid.org/0000-0002-7798-6707, Huber, N., Mohr, J., Edelmann-Stephan, B., Austin, R., Brandt, S., Palandri, F. ORCID: https://orcid.org/0000-0001-8367-5668, Schröder, N., Isermann, B., Edlich, F., Sinha, A.U., Ungelenk, M., Hübner, C.A., Zeiser, R. ORCID: https://orcid.org/0000-0001-6565-3393, Rahmig, S., Waskow, C. ORCID: https://orcid.org/0000-0003-3261-0922, Coldham, I. ORCID: https://orcid.org/0000-0003-4602-6292, Ernst, T., Hochhaus, A., Jilg, S., Jost, P.J. ORCID: https://orcid.org/0000-0003-2454-0362, Mullally, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mertens, P.R., Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209, Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799 and Heidel, F.H. ORCID: https://orcid.org/0000-0003-2438-1955
Nature 588 (7836): 157-163. 3 December 2020

Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1.
Tausch, E., Beck, P., Schlenk, R.F., Jebaraj, B.M.C., Dolnik, A., Yosifov, D.Y., Hillmen, P., Offner, F., Janssens, A., Babu, K.G., Grosicki, S., Mayer, J., Panagiotidis, P., McKeown, A., Gupta, I.V., Skorupa, A., Pallaud, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mertens, D., Döhner, H. and Stilgenbauer, S.
Haematologica 105 (10): 2440-2447. October 2020

Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells.
Raffel, S. ORCID: https://orcid.org/0000-0003-4671-1097, Klimmeck, D., Falcone, M. ORCID: https://orcid.org/0000-0003-0906-5735, Demir, A. ORCID: https://orcid.org/0000-0001-7327-7682, Pouya, A. ORCID: https://orcid.org/0000-0002-9458-1648, Zeisberger, P., Lutz, C., Tinelli, M., Bischel, O., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Thiede, C., Flörcken, A., Westermann, J., Ehninger, G., Ho, A.D., Müller-Tidow, C. ORCID: https://orcid.org/0000-0002-7166-5232, Gu, Z., Herrmann, C. ORCID: https://orcid.org/0000-0003-4989-4722, Krijgsveld, J. ORCID: https://orcid.org/0000-0001-7549-9326, Trumpp, A. ORCID: https://orcid.org/0000-0002-6212-3466 and Hansson, J. ORCID: https://orcid.org/0000-0001-9174-8089
Blood 136 (13): 1507-1519. 24 September 2020

Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
Yusuf, R.Z., Saez, B., Sharda, A., van Gastel, N. ORCID: https://orcid.org/0000-0002-0563-3590, Yu, V.W.C. ORCID: https://orcid.org/0000-0002-6658-0285, Baryawno, N., Scadden, E.W., Acharya, S., Chattophadhyay, S., Huang, C., Viswanathan, V. ORCID: https://orcid.org/0000-0001-9878-3629, S'aulis, D., Cobert, J., Sykes, D.B. ORCID: https://orcid.org/0000-0002-9788-0221, Keibler, M.A., Das, S., Hutchinson, J.N. ORCID: https://orcid.org/0000-0002-7804-7576, Churchill, M. ORCID: https://orcid.org/0000-0001-7202-3891, Mukherjee, S., Lee, D. ORCID: https://orcid.org/0000-0001-6828-401X, Mercier, F., Doench, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Logan, D.J., Schreiber, S., Stephanopoulos, G., Rizzo, W.B. and Scadden, D.T.
Blood 136 (11): 1303-1316. 10 September 2020

Endothelial damage and dysfunction in acute graft-versus-host disease.
Cordes, S., Mokhtari, Z., Bartosova, M., Mertlitz, S., Riesner, K., Shi, Y., Mengwasser, J., Kalupa, M., McGeary, A., Schleifenbaum, J. ORCID: https://orcid.org/0000-0002-3195-1517, Schrezenmeier, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Diaz-Ricart, M., Palomo, M., Carrreras, E., Beutel, G., Schmitt, C.P., Beilhack, A. and Penack, O.
Haematologica 106 (8): 2147-2160. 1 August 2020

Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients.
Lauber, C., Correia, N., Trumpp, A., Rieger, M.A., Dolnik, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Roeder, I. and Seifert, M. ORCID: https://orcid.org/0000-0002-2844-053X
Scientific Reports 10 (1): 12761. 29 July 2020

Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia.
Becker, H. ORCID: https://orcid.org/0000-0002-6919-4048, Pfeifer, D., Ihorst, G., Pantic, M., Wehrle, J., Rüter, B.H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Hackanson, B., Germing, U., Kuendgen, A., Platzbecker, U., Döhner, K., Ganser, A., Hagemeijer, A., Wijermans, P.W., Döhner, H., Duyster, J. and Lübbert, M.
Annals of Hematology 99 (7): 1551-1560. July 2020

Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax.
Tausch, E., Schneider, C., Robrecht, S., Zhang, C., Dolnik, A., Bloehdorn, J., Bahlo, J., Al-Sawaf, O., Ritgen, M., Fink, A.M., Eichhorst, B., Kreuzer, K.A., Tandon, M., Humphrey, K., Jiang, Y., Schary, W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mertens, D., Lurà, M.P., Kneba, M., Döhner, H., Fischer, K., Hallek, M. and Stilgenbauer, S.
Blood 135 (26): 2402-2412. 25 June 2020

Core outcome set measurement for future clinical trials in acute myeloid leukemia: the HARMONY study protocol using a multi-stakeholder consensus-based Delphi process and a final consensus meeting.
Lang, K.M. ORCID: https://orcid.org/0000-0001-8855-884X, Harrison, K.L., Williamson, P.R., Huntly, B.J.P., Ossenkoppele, G., Geissler, J., Bereczky, T., Hernández-Rivas, J.M., Chevrou-Séverac, H., Goodbody, R., Schulze-Rath, R. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Trials 21 (1): 437. 27 May 2020

Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.
Edelmann, J., Holzmann, K., Tausch, E., Saunderson, E.A., Jebaraj, B.M.C., Steinbrecher, D., Dolnik, A., Blätte, T.J., Landau, D.A., Saub, J., Estenfelder, S., Ibach, S., Cymbalista, F., Leblond, V., Delmer, A., Bahlo, J., Robrecht, S., Fischer, K., Goede, V., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Wu, C.J., Mertens, D., Ficz, G., Gribben, J.G., Hallek, M., Döhner, H. and Stilgenbauer, S.
Haematologica 105 (5): 1379-1390. May 2020

Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.
Greiner, J. ORCID: https://orcid.org/0000-0003-1256-173X, Götz, M., Hofmann, S., Schrezenmeier, H., Wiesneth, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, H. and Schneider, V.
Cancer Immunology Immunotherapy 69 (4): 629-640. April 2020

Functional classification of TP53 mutations in acute myeloid leukemia.
Dutta, S., Pregartner, G., Rücker, F.G., Heitzer, E. ORCID: https://orcid.org/0000-0002-8815-7859, Zebisch, A. ORCID: https://orcid.org/0000-0002-4861-7021, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Berghold, A., Döhner, K. and Sill, H. ORCID: https://orcid.org/0000-0003-0993-4371
Cancers 12 (3): 637. 10 March 2020

Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1).
Meyer, T., Jahn, N., Lindner, S., Röhner, L., Dolnik, A., Weber, D., Scheffold, A., Köpff, S., Paschka, P., Gaidzik, V.I., Heckl, D., Wiese, S., Ebert, B.L., Döhner, H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, K. and Krönke, J.
Leukemia 34 (2): 404-415. February 2020

Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel.
Jiang, S., Penack, O., Terzer, T., Schult, D., Majer-Lauterbach, J., Radujkovic, A., Blau, I.W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Müller-Tidow, C., Dreger, P. and Luft, T.
Haematologica 106 (2): 446-453. February 2020

Therapeutic targeting of preleukemia cells in a mouse model of mutant acute myeloid leukemia.
Uckelmann, H.J. ORCID: https://orcid.org/0000-0003-2048-7357, Kim, S.M. ORCID: https://orcid.org/0000-0003-0015-1821, Wong, E.M., Hatton, C. ORCID: https://orcid.org/0000-0001-9903-4291, Giovinazzo, H., Gadrey, J.Y. ORCID: https://orcid.org/0000-0001-7749-7703, Krivtsov, A.V. ORCID: https://orcid.org/0000-0002-5511-1686, Rücker, F.G., Döhner, K., McGeehan, G.M., Levine, R.L., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Vassiliou, G.S. ORCID: https://orcid.org/0000-0003-4337-8022 and Armstrong, S.A. ORCID: https://orcid.org/0000-0002-9099-4728
Science 367 (6477): 586-590. 31 January 2020