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2026

Trem2 exacerbates ischemic brain injury through Gpnmb in a photothrombotic stroke model.
Chen, Xuezhen, Li, Kunyu, Liu, Siyu, Zhao, Junyi, Tiwari, Sagun ORCID logoORCID: https://orcid.org/0000-0001-5207-9900, Zeng, Fan ORCID logoORCID: https://orcid.org/0000-0002-4016-7302, Zhao, Yue, Zhang, Pingping, Tang, Han, Zhao, Hong, Kettenmann, Helmut ORCID logoORCID: https://orcid.org/0000-0001-8208-0291, Xiang, Xianyuan and Zhu, Xinzhou ORCID logoORCID: https://orcid.org/0000-0003-2414-1257
Proceedings of the National Academy of Sciences of the United States of America 123 (16): e2523148123. 21 April 2026

Chronic infection perturbs the affinity hierarchy of antiviral B cells.
Dimitrova, Mirela, Abreu-Mota, Tiago, Fixemer, Jonas, Bonilla, Weldy V., Marx, Anna-Friederike, Lu, Min, Tintignac, Karen, Kastner, Anna Lena, Ertuna, Yusuf I., Florova, Marianna ORCID logoORCID: https://orcid.org/0009-0008-9529-7041, Ciancaglini, Matias ORCID logoORCID: https://orcid.org/0000-0002-1296-5606, Narr, Kerstin, Stauffer, Karsten, Roux, Julien, Demougin, Philippe ORCID logoORCID: https://orcid.org/0009-0002-2820-9909, Wagner, Ingrid, Merkler, Doron ORCID logoORCID: https://orcid.org/0000-0002-0247-2007 and Pinschewer, Daniel D. ORCID logoORCID: https://orcid.org/0000-0002-1594-3189
Proceedings of the National Academy of Sciences of the United States of America 123 (14): e2532422123. 7 April 2026

HairTime: a noninvasive assay for estimating circadian phase from a single hair sample.
Maier, Bert ORCID logoORCID: https://orcid.org/0000-0002-5254-008X, Pilz, Luísa K. ORCID logoORCID: https://orcid.org/0000-0001-7328-6204, Özcakir, Selin, Rahjouei, Ali ORCID logoORCID: https://orcid.org/0000-0003-3973-6333, Abdo, Ashraf N., de Zeeuw, Jan ORCID logoORCID: https://orcid.org/0000-0002-4052-6782, Kunz, Dieter and Kramer, Achim ORCID logoORCID: https://orcid.org/0000-0001-9671-6078
Proceedings of the National Academy of Sciences of the United States of America 123 (13): e2514928123. 31 March 2026

2025

Cryosectioning-enhanced super-resolution microscopy for single-protein imaging across cells and tissues.
Stein, Johannes, Ericsson, Maria, Nofal, Michel, Magni, Lorenzo, Aufmkolk, Sarah, McMillan, Ryan B., Breimann, Laura ORCID logoORCID: https://orcid.org/0000-0001-7702-5749, Herlihy, Conor P., Lee, S. Dean, Willemin, Andréa ORCID logoORCID: https://orcid.org/0000-0002-4370-6914, Wohlmann, Jens, Arguedas-Jimenez, Laura ORCID logoORCID: https://orcid.org/0009-0004-2240-7781, Yin, Peng, Pombo, Ana ORCID logoORCID: https://orcid.org/0000-0002-7493-6288, Church, George M. and Wu, Chao-Ting
Proceedings of the National Academy of Sciences of the United States of America 122 (32): e2504578122. 12 August 2025

Cell type-specific purifying selection of synonymous mitochondrial DNA variation.
Lareau, Caleb A. ORCID logoORCID: https://orcid.org/0000-0003-4179-4807, Maschmeyer, Patrick ORCID logoORCID: https://orcid.org/0000-0002-1705-5302, Yin, Yajie ORCID logoORCID: https://orcid.org/0000-0002-2220-005X, Gutierrez, Jacob C., Dhindsa, Ryan S. ORCID logoORCID: https://orcid.org/0000-0002-8965-0813, Gribling-Burrer, Anne-Sophie, Zielinski, Sebastian ORCID logoORCID: https://orcid.org/0000-0001-5070-1209, Hsieh, Yu-Hsin ORCID logoORCID: https://orcid.org/0000-0003-3037-8728, Nitsch, Lena ORCID logoORCID: https://orcid.org/0000-0003-0775-1969, Dimitrova, Veronika ORCID logoORCID: https://orcid.org/0009-0007-6915-7136, Nalbant, Benan, Buquicchio, Frank A. ORCID logoORCID: https://orcid.org/0000-0002-9910-4947, Abay, Tsion ORCID logoORCID: https://orcid.org/0009-0009-0024-2732, Stickels, Robert R., Ulirsch, Jacob C., Yan, Patrick, Wang, Fangyi ORCID logoORCID: https://orcid.org/0009-0000-8310-3088, Miao, Zhuang, Sandor, Katalin ORCID logoORCID: https://orcid.org/0000-0003-2892-4865, Daniel, Bence, Liu, Vincent, Mendez, Paul L. ORCID logoORCID: https://orcid.org/0000-0003-2025-7981, Knaus, Petra, Meyer, Manpreet ORCID logoORCID: https://orcid.org/0009-0004-5700-8529, Greenleaf, William J. ORCID logoORCID: https://orcid.org/0000-0003-1409-3095, Kundaje, Anshul ORCID logoORCID: https://orcid.org/0000-0003-3084-2287, Smyth, Redmond P. ORCID logoORCID: https://orcid.org/0000-0002-1580-0671, Munschauer, Mathias ORCID logoORCID: https://orcid.org/0000-0001-6143-4548, Ludwig, Leif S. ORCID logoORCID: https://orcid.org/0000-0002-2916-2164 and Satpathy, Ansuman T. ORCID logoORCID: https://orcid.org/0000-0002-5167-537X
Proceedings of the National Academy of Sciences of the United States of America 122 (30): e2505704122. 29 July 2025

Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.
Mobach, S. ORCID logoORCID: https://orcid.org/0000-0001-8320-214X, Bergkamp, N.D. ORCID logoORCID: https://orcid.org/0000-0001-5692-5975, Ma, Z. ORCID logoORCID: https://orcid.org/0000-0003-4285-6598, Haselager, M.V. ORCID logoORCID: https://orcid.org/0000-0002-1410-7285, Anbuhl, S.M., Jurriens, D., van den Bor, J. ORCID logoORCID: https://orcid.org/0000-0002-2411-2379, Wang, Z., Crudden, C., Roos, J.L. ORCID logoORCID: https://orcid.org/0009-0004-4884-7726, Perez Almeria, C.V. ORCID logoORCID: https://orcid.org/0000-0002-7312-8529, Boergonje, R.A., Lohse, M.J. ORCID logoORCID: https://orcid.org/0000-0002-0599-3510, Bosma, R., Eldering, E. ORCID logoORCID: https://orcid.org/0000-0003-0561-6640, Siderius, M. ORCID logoORCID: https://orcid.org/0000-0003-3630-4228, Wu, W., Spaargaren, M. ORCID logoORCID: https://orcid.org/0000-0002-3135-5109, Tonino, S.H., Kater, A.P., Smit, M.J. ORCID logoORCID: https://orcid.org/0000-0003-2713-0238 and Heukers, R. ORCID logoORCID: https://orcid.org/0000-0003-4498-7751
Proceedings of the National Academy of Sciences of the United States of America 122 (24): e2424186122. 17 June 2025

Gonadal sex and temperature independently influence germ cell differentiation and meiotic progression in Trachemys scripta.
Hatkevich, T., Tezak, B.M., Acemel, R.D. ORCID logoORCID: https://orcid.org/0000-0003-4120-0140, Yee Chung, V.W., Lupiáñez, D.G. ORCID logoORCID: https://orcid.org/0000-0002-3165-036X and Capel, B. ORCID logoORCID: https://orcid.org/0000-0002-6587-0969
Proceedings of the National Academy of Sciences of the United States of America 122 (1): e2413191121. 7 January 2025

2024

Architecture of the Sap S-layer of Bacillus anthracis revealed by integrative structural biology.
Sogues, A. ORCID logoORCID: https://orcid.org/0000-0002-5752-6009, Leigh, K. ORCID logoORCID: https://orcid.org/0000-0002-6467-3330, Halingstad, E.V., Van der Verren, S.E., Cecil, A.J., Fioravanti, A. ORCID logoORCID: https://orcid.org/0000-0002-4065-0839, Pak, A.J. ORCID logoORCID: https://orcid.org/0000-0003-2823-6480, Kudryashev, M. ORCID logoORCID: https://orcid.org/0000-0003-3550-6274 and Remaut, H. ORCID logoORCID: https://orcid.org/0000-0002-9775-4102
Proceedings of the National Academy of Sciences of the United States of America 121 (51): e2415351121. 17 December 2024

Molecular architecture of synaptic vesicles.
Kravčenko, U. ORCID logoORCID: https://orcid.org/0009-0004-7176-8444, Ruwolt, M., Kroll, J. ORCID logoORCID: https://orcid.org/0000-0003-4243-4088, Yushkevich, A. ORCID logoORCID: https://orcid.org/0000-0002-8729-9281, Zenkner, M., Ruta, J. ORCID logoORCID: https://orcid.org/0009-0007-0524-6885, Lotfy, R., Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630, Rosenmund, C. ORCID logoORCID: https://orcid.org/0000-0002-3905-2444, Liu, F. and Kudryashev, M. ORCID logoORCID: https://orcid.org/0000-0003-3550-6274
Proceedings of the National Academy of Sciences of the United States of America 121 (49): e2407375121. 3 December 2024

Arabidopsis uses a molecular grounding mechanism and a biophysical circuit breaker to limit floral abscission signaling.
Taylor, I.W. ORCID logoORCID: https://orcid.org/0000-0002-6535-8658, Patharkar, O.R. ORCID logoORCID: https://orcid.org/0000-0002-1242-6549, Mijar, M. ORCID logoORCID: https://orcid.org/0000-0001-7771-3357, Hsu, C.W. ORCID logoORCID: https://orcid.org/0000-0003-3709-9748, Baer, J., Niederhuth, C.E. ORCID logoORCID: https://orcid.org/0000-0003-3268-9079, Ohler, U. ORCID logoORCID: https://orcid.org/0000-0002-0881-3116, Benfey, P.N. ORCID logoORCID: https://orcid.org/0000-0001-5302-758X and Walker, J.C. ORCID logoORCID: https://orcid.org/0000-0002-2050-1641
Proceedings of the National Academy of Sciences of the United States of America 121 (44): e2405806121. 29 October 2024

Incomplete transcriptional dosage compensation of chicken and platypus sex chromosomes is balanced by post-transcriptional compensation.
Lister, N.C. ORCID logoORCID: https://orcid.org/0000-0002-6597-4784, Milton, A.M. ORCID logoORCID: https://orcid.org/0000-0002-2847-2777, Patel, H.R. ORCID logoORCID: https://orcid.org/0000-0003-3169-049X, Waters, S.A. ORCID logoORCID: https://orcid.org/0000-0003-1144-5411, Hanrahan, B.J., McIntyre, K.L., Livernois, A.M., Horspool, W.B., Wee, L.K., Ringel, A.R., Mundlos, S., Robson, M.I. ORCID logoORCID: https://orcid.org/0000-0003-1126-3538, Shearwin-Whyatt, L., Grützner, F. ORCID logoORCID: https://orcid.org/0000-0002-3088-7314, Graves, J.A.M. ORCID logoORCID: https://orcid.org/0000-0001-6480-7856, Ruiz-Herrera, A. ORCID logoORCID: https://orcid.org/0000-0003-3868-6151 and Waters, P.D. ORCID logoORCID: https://orcid.org/0000-0002-4689-8747
Proceedings of the National Academy of Sciences of the United States of America 121 (32): e2322360121. 6 August 2024

IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota.
Röwekamp, I., Maschirow, L. ORCID logoORCID: https://orcid.org/0000-0002-7727-2544, Rabes, A., Fiocca Vernengo, F., Hamann, L. ORCID logoORCID: https://orcid.org/0000-0003-4719-2583, Heinz, G.A. ORCID logoORCID: https://orcid.org/0000-0002-9330-3689, Mashreghi, M.F. ORCID logoORCID: https://orcid.org/0000-0002-8015-6907, Caesar, S., Milek, M. ORCID logoORCID: https://orcid.org/0000-0002-0803-8439, Fagundes Fonseca, A.C. ORCID logoORCID: https://orcid.org/0009-0003-9027-8136, Wienhold, S.M., Nouailles, G. ORCID logoORCID: https://orcid.org/0000-0003-1973-3119, Yao, L. ORCID logoORCID: https://orcid.org/0000-0002-0482-9604, Mousavi, S., Bruder, D. ORCID logoORCID: https://orcid.org/0000-0003-3066-189X, Boehme, J.D. ORCID logoORCID: https://orcid.org/0000-0002-6257-0952, Puzianowska-Kuznicka, M. ORCID logoORCID: https://orcid.org/0000-0001-5295-3848, Beule, D. ORCID logoORCID: https://orcid.org/0000-0002-3284-0632, Witzenrath, M., Löhning, M. ORCID logoORCID: https://orcid.org/0000-0001-6382-7281, Klose, C.S.N., Heimesaat, M.M. ORCID logoORCID: https://orcid.org/0000-0001-6399-651X, Diefenbach, A. ORCID logoORCID: https://orcid.org/0000-0002-9176-9530 and Opitz, B. ORCID logoORCID: https://orcid.org/0000-0003-1276-836X
Proceedings of the National Academy of Sciences of the United States of America 121 (22): e2310864121. 28 May 2024

Structure and function of the hippocampal CA3 module.
Sammons, R.P. ORCID logoORCID: https://orcid.org/0000-0001-9167-9263, Vezir, M., Moreno-Velasquez, L. ORCID logoORCID: https://orcid.org/0000-0001-9735-0039, Cano, G. ORCID logoORCID: https://orcid.org/0000-0003-2076-1547, Orlando, M. ORCID logoORCID: https://orcid.org/0000-0002-9017-0251, Sievers, M., Grasso, E. ORCID logoORCID: https://orcid.org/0009-0009-0746-0193, Metodieva, V.D. ORCID logoORCID: https://orcid.org/0000-0003-1942-5140, Kempter, R. ORCID logoORCID: https://orcid.org/0000-0002-5344-2983, Schmidt, H. and Schmitz, D. ORCID logoORCID: https://orcid.org/0000-0003-2741-5241
Proceedings of the National Academy of Sciences of the United States of America 121 (6): e2312281120. 6 February 2024

A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea.
Mottaghinia, S. ORCID logoORCID: https://orcid.org/0000-0002-9409-3302, Stenzel, S. ORCID logoORCID: https://orcid.org/0000-0003-0926-7759, Tsangaras, K. ORCID logoORCID: https://orcid.org/0000-0001-7454-0454, Nikolaidis, N. ORCID logoORCID: https://orcid.org/0000-0002-5633-1883, Laue, M. ORCID logoORCID: https://orcid.org/0000-0002-6474-9139, Müller, K. ORCID logoORCID: https://orcid.org/0000-0003-1749-4863, Hölscher, H. ORCID logoORCID: https://orcid.org/0009-0006-9621-3001, Löber, U. ORCID logoORCID: https://orcid.org/0000-0001-7468-9531, McEwen, G.K., Donnellan, S.C. ORCID logoORCID: https://orcid.org/0000-0002-5448-3226, Rowe, K.C. ORCID logoORCID: https://orcid.org/0000-0002-1215-9153, Aplin, K.P., Goffinet, C. ORCID logoORCID: https://orcid.org/0000-0002-3959-004X and Greenwood, A.D. ORCID logoORCID: https://orcid.org/0000-0002-8249-1565
Proceedings of the National Academy of Sciences of the United States of America 121 (6): e2220392121. 1 February 2024

2023

Germline C1GALT1C1 mutation causes a multisystem chaperonopathy.
Erger, F. ORCID logoORCID: https://orcid.org/0000-0002-2768-1702, Aryal, R.P., Reusch, B., Matsumoto, Y. ORCID logoORCID: https://orcid.org/0000-0003-2606-2616, Meyer, R., Zeng, J., Knopp, C., Noel, M., Muerner, L., Wenzel, A., Kohl, S., Tschernoster, N., Rappl, G., Rouvet, I., Schröder-Braunstein, J., Seibert, F.S., Thiele, H., Häusler, M.G., Weber, L.T. ORCID logoORCID: https://orcid.org/0000-0003-4116-598X, Büttner-Herold, M., Elbracht, M., Cummings, S.F. ORCID logoORCID: https://orcid.org/0000-0002-8918-5034, Altmüller, J. ORCID logoORCID: https://orcid.org/0000-0003-4372-1521, Habbig, S., Cummings, R.D. and Beck, B.B. ORCID logoORCID: https://orcid.org/0000-0003-0495-7670
Proceedings of the National Academy of Sciences of the United States of America 120 (22): e2211087120. 30 May 2023

TapA acts as specific chaperone in TasA filament formation by strand complementation.
Roske, Y. ORCID logoORCID: https://orcid.org/0000-0001-6237-388X, Lindemann, F. ORCID logoORCID: https://orcid.org/0000-0002-5183-3120, Diehl, A. ORCID logoORCID: https://orcid.org/0000-0001-7295-9972, Cremer, N., Higman, V.A. ORCID logoORCID: https://orcid.org/0000-0002-3204-2665, Schlegel, B., Leidert, M., Driller, K., Turgay, K. ORCID logoORCID: https://orcid.org/0000-0002-8959-492X, Schmieder, P. ORCID logoORCID: https://orcid.org/0000-0001-9968-9327, Heinemann, U. ORCID logoORCID: https://orcid.org/0000-0002-8191-3850 and Oschkinat, H. ORCID logoORCID: https://orcid.org/0000-0002-4384-9544
Proceedings of the National Academy of Sciences of the United States of America 120 (17): e2217070120. 25 April 2023

Mouse models of human multiple myeloma subgroups.
Winkler, W. ORCID logoORCID: https://orcid.org/0000-0001-8807-9259, Farré Díaz, C. ORCID logoORCID: https://orcid.org/0000-0003-4306-2108, Blanc, E. ORCID logoORCID: https://orcid.org/0000-0002-4369-0254, Napieczynska, H. ORCID logoORCID: https://orcid.org/0000-0001-5091-1185, Langner, P. ORCID logoORCID: https://orcid.org/0009-0007-4313-3152, Werner, M. ORCID logoORCID: https://orcid.org/0000-0003-1200-807X, Walter, B. ORCID logoORCID: https://orcid.org/0000-0002-0844-5958, Wollert-Wulf, B. ORCID logoORCID: https://orcid.org/0009-0000-0257-4049, Yasuda, T. ORCID logoORCID: https://orcid.org/0000-0001-9997-6852, Heuser, A. ORCID logoORCID: https://orcid.org/0000-0002-3334-960X, Beule, D. ORCID logoORCID: https://orcid.org/0000-0002-3284-0632, Mathas, S. ORCID logoORCID: https://orcid.org/0000-0001-9626-1413, Anagnostopoulos, I., Rosenwald, A., Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370 and Janz, M. ORCID logoORCID: https://orcid.org/0000-0002-1127-0044
Proceedings of the National Academy of Sciences of the United States of America 120 (10): e2219439120. 7 March 2023

Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
Petrović, S. ORCID logoORCID: https://orcid.org/0000-0003-2238-8651, Roske, Y. ORCID logoORCID: https://orcid.org/0000-0001-6237-388X, Rami, B., Phan, M.H.Q., Panakova, D. ORCID logoORCID: https://orcid.org/0000-0002-8739-6225 and Heinemann, U. ORCID logoORCID: https://orcid.org/0000-0002-8191-3850
Proceedings of the National Academy of Sciences of the United States of America 120 (4): e2208941120. 24 January 2023

2022

Different classes of genomic inserts contribute to human antibody diversity.
Lebedin, M. ORCID logoORCID: https://orcid.org/0000-0002-3877-7195, Foglierini, M., Khorkova, S. ORCID logoORCID: https://orcid.org/0000-0002-7873-2290, Vázquez García, C. ORCID logoORCID: https://orcid.org/0000-0003-4583-7616, Ratswohl, C. ORCID logoORCID: https://orcid.org/0000-0001-5413-0730, Davydov, A.N., Turchaninova, M.A. ORCID logoORCID: https://orcid.org/0000-0002-8874-0286, Daubenberger, C. ORCID logoORCID: https://orcid.org/0000-0001-7136-0642, Chudakov, D.M. ORCID logoORCID: https://orcid.org/0000-0003-0430-790X, Lanzavecchia, A. and de la Rosa, K. ORCID logoORCID: https://orcid.org/0000-0003-4809-3157
Proceedings of the National Academy of Sciences of the United States of America 119 (36): e2205470119. 6 September 2022

Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6.
Cockman, M.E. ORCID logoORCID: https://orcid.org/0000-0002-3310-4821, Sugimoto, Y. ORCID logoORCID: https://orcid.org/0000-0003-1646-7679, Pegg, H.B. ORCID logoORCID: https://orcid.org/0000-0003-0810-3349, Masson, N. ORCID logoORCID: https://orcid.org/0000-0002-9714-905X, Salah, E. ORCID logoORCID: https://orcid.org/0000-0001-7552-4966, Tumber, A., Flynn, H.R. ORCID logoORCID: https://orcid.org/0000-0001-7002-9130, Kirkpatrick, J.M. ORCID logoORCID: https://orcid.org/0000-0001-9291-7294, Schofield, C.J. ORCID logoORCID: https://orcid.org/0000-0002-0290-6565 and Ratcliffe, P.J. ORCID logoORCID: https://orcid.org/0000-0002-2853-806X
Proceedings of the National Academy of Sciences of the United States of America 119 (32): e2201483119. 9 August 2022

Functional modulation of PTH1R activation and signaling by RAMP2.
Nemec, K. ORCID logoORCID: https://orcid.org/0000-0002-3555-5853, Schihada, H. ORCID logoORCID: https://orcid.org/0000-0002-1889-1636, Kleinau, G. ORCID logoORCID: https://orcid.org/0000-0003-2131-671X, Zabel, U., Grushevsky, E.O. ORCID logoORCID: https://orcid.org/0000-0003-1779-8306, Scheerer, P. ORCID logoORCID: https://orcid.org/0000-0001-5028-2075, Lohse, M.J. ORCID logoORCID: https://orcid.org/0000-0002-0599-3510 and Maiellaro, I. ORCID logoORCID: https://orcid.org/0000-0001-5595-8011
Proceedings of the National Academy of Sciences of the United States of America 119 (32): e2122037119. 9 August 2022

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model.
Axelsson Raja, A., Wakimoto, H., DeLaughter, D.M., Reichart, D., Gorham, J., Conner, D.A., Lun, M., Probst, C.K., Sakai, N., Knipe, R.S., Montesi, S.B., Shea, B., Adam, L.P., Leinwand, L.A. ORCID logoORCID: https://orcid.org/0000-0003-1470-4810, Wan, W., Choi, E.S., Lindberg, E.L. ORCID logoORCID: https://orcid.org/0000-0002-2979-433X, Patone, G. ORCID logoORCID: https://orcid.org/0000-0002-7242-0341, Noseda, M., Hübner, N. ORCID logoORCID: https://orcid.org/0000-0002-1218-6223, Seidman, C.E. ORCID logoORCID: https://orcid.org/0000-0001-6380-1209, Tager, A.M., Seidman, J.G. ORCID logoORCID: https://orcid.org/0000-0002-9082-3566 and Ho, C.Y. ORCID logoORCID: https://orcid.org/0000-0002-7334-7924
Proceedings of the National Academy of Sciences of the United States of America 119 (28): e2204174119. 12 July 2022

Brain-wide interactions during hippocampal sharp wave ripples.
Nitzan, N. ORCID logoORCID: https://orcid.org/0000-0002-9320-4787, Swanson, R., Schmitz, D. ORCID logoORCID: https://orcid.org/0000-0003-2741-5241 and Buzsáki, G. ORCID logoORCID: https://orcid.org/0000-0002-3100-4800
Proceedings of the National Academy of Sciences of the United States of America 119 (20): e2200931119. 17 May 2022

NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
Doffo, J., Bamopoulos, S.A. ORCID logoORCID: https://orcid.org/0000-0002-5997-7735, Köse, H. ORCID logoORCID: https://orcid.org/0000-0003-4307-5654, Orben, F. ORCID logoORCID: https://orcid.org/0000-0002-2196-8702, Zang, C., Pons, M., den Dekker, A.T., Brouwer, R.W.W., Baluapuri, A. ORCID logoORCID: https://orcid.org/0000-0002-3723-7891, Habringer, S. ORCID logoORCID: https://orcid.org/0000-0002-3976-9592, Reichert, M., Illendula, A., Krämer, O.H., Schick, M. ORCID logoORCID: https://orcid.org/0009-0003-8626-0611, Wolf, E. ORCID logoORCID: https://orcid.org/0000-0002-5299-6335, van IJcken, W.F.J. ORCID logoORCID: https://orcid.org/0000-0002-0421-8301, Esposito, I., Keller, U. ORCID logoORCID: https://orcid.org/0000-0002-8485-1958, Schneider, G. ORCID logoORCID: https://orcid.org/0000-0003-1840-4508 and Wirth, M. ORCID logoORCID: https://orcid.org/0000-0002-8340-0872
Proceedings of the National Academy of Sciences of the United States of America 119 (9): e2105691119. 1 March 2022

2021

ENHANCED GRAVITROPISM 2 encodes a STERILE ALPHA MOTIF–containing protein that controls root growth angle in barley and wheat.
Kirschner, G.K., Rosignoli, S. ORCID logoORCID: https://orcid.org/0000-0002-4319-8761, Guo, L. ORCID logoORCID: https://orcid.org/0000-0003-0406-6966, Vardanega, I. ORCID logoORCID: https://orcid.org/0000-0002-3642-9381, Imani, J. ORCID logoORCID: https://orcid.org/0000-0001-8265-1656, Altmüller, J. ORCID logoORCID: https://orcid.org/0000-0003-4372-1521, Milner, S.G., Balzano, R: ORCID logoORCID: https://orcid.org/0000-0001-7405-4456, Nagel, K.A. ORCID logoORCID: https://orcid.org/0000-0003-3025-0388, Pflugfelder, D. ORCID logoORCID: https://orcid.org/0000-0001-6187-2935, Forestan, C. ORCID logoORCID: https://orcid.org/0000-0002-1712-825X, Bovina, R. ORCID logoORCID: https://orcid.org/0000-0001-6170-4587, Koller, R. ORCID logoORCID: https://orcid.org/0000-0001-7251-7242, Stöcker, T.G. ORCID logoORCID: https://orcid.org/0000-0001-7184-9472, Mascher, M., Simmonds, J., Uauy, C. ORCID logoORCID: https://orcid.org/0000-0002-9814-1770, Schoof, H. ORCID logoORCID: https://orcid.org/0000-0002-1527-3752, Tuberosa, R. ORCID logoORCID: https://orcid.org/0000-0001-9143-9569, Salvi, S. ORCID logoORCID: https://orcid.org/0000-0002-0338-8894 and Hochholdinger, F. ORCID logoORCID: https://orcid.org/0000-0002-5155-0884
Proceedings of the National Academy of Sciences of the United States of America 118 (35): e2101526118. 31 August 2021

The magnitude of germinal center reactions is restricted by a fixed number of preexisting niches.
Avancena, P., Song, T. ORCID logoORCID: https://orcid.org/0000-0002-6994-6609, Yao, Y. ORCID logoORCID: https://orcid.org/0000-0003-4637-9063, Fehlner-Peach, H. ORCID logoORCID: https://orcid.org/0000-0003-3021-1741, Diamond, B. ORCID logoORCID: https://orcid.org/0000-0002-3250-3804, Gu, H. ORCID logoORCID: https://orcid.org/0000-0002-0019-6168, Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370 and Zou, Y.R. ORCID logoORCID: https://orcid.org/0000-0002-3864-8908
Proceedings of the National Academy of Sciences of the United States of America 118 (30): e2100576118. 27 July 2021

Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor.
Ganichkin, O.M., Vancraenenbroeck, R. ORCID logoORCID: https://orcid.org/0000-0003-2685-2749, Rosenblum, G., Hofmann, H. ORCID logoORCID: https://orcid.org/0000-0003-1669-3158, Mikhailov, A.S. ORCID logoORCID: https://orcid.org/0000-0002-2416-8401, Daumke, O. ORCID logoORCID: https://orcid.org/0000-0002-6190-1414 and Noel, J.K. ORCID logoORCID: https://orcid.org/0000-0003-3168-6036
Proceedings of the National Academy of Sciences of the United States of America 118 (28): e2101144118. 13 July 2021

Skin sodium is increased in male patients with multiple sclerosis and related animal models.
Huhn, K. ORCID logoORCID: https://orcid.org/0000-0002-6965-2117, Linz, P. ORCID logoORCID: https://orcid.org/0000-0002-8232-1443, Pemsel, F., Michalke, B. ORCID logoORCID: https://orcid.org/0000-0001-6376-2588, Seyferth, S., Kopp, C., Chaudri, M.A., Rothhammer, V., Dörfler, A., Uder, M. ORCID logoORCID: https://orcid.org/0000-0001-6238-4247, Nagel, A.M. ORCID logoORCID: https://orcid.org/0000-0003-0948-1421, Müller, D.N. ORCID logoORCID: https://orcid.org/0000-0003-3650-5644, Waschbisch, A. ORCID logoORCID: https://orcid.org/0000-0002-9305-1979, Lee, D.H., Bäuerle, T., Linker, R.A. ORCID logoORCID: https://orcid.org/0000-0002-8740-3106 and Haase, S. ORCID logoORCID: https://orcid.org/0000-0002-9371-4314
Proceedings of the National Academy of Sciences of the United States of America 118 (28): e2102549118. 13 July 2021

Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes.
Bathe-Peters, M. ORCID logoORCID: https://orcid.org/0000-0002-9618-0856, Gmach, P. ORCID logoORCID: https://orcid.org/0000-0002-5258-0321, Boltz, H.H. ORCID logoORCID: https://orcid.org/0000-0003-0013-5186, Einsiedel, J., Gotthardt, M. ORCID logoORCID: https://orcid.org/0000-0003-1788-3172, Hübner, H. ORCID logoORCID: https://orcid.org/0000-0002-7892-599X, Gmeiner, P. ORCID logoORCID: https://orcid.org/0000-0002-4127-197X, Lohse, M.J. ORCID logoORCID: https://orcid.org/0000-0002-0599-3510 and Annibale, P. ORCID logoORCID: https://orcid.org/0000-0003-3208-5347
Proceedings of the National Academy of Sciences of the United States of America 118 (23): e2101119118. 8 June 2021

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J. ORCID logoORCID: https://orcid.org/0000-0001-7205-732X, Grinat, J. ORCID logoORCID: https://orcid.org/0000-0003-0152-4941, Kosel, F., Liu, L., Kunz, S. ORCID logoORCID: https://orcid.org/0000-0002-0131-3506, Vidal, R.O. ORCID logoORCID: https://orcid.org/0000-0003-4217-2014, Keil, M. ORCID logoORCID: https://orcid.org/0000-0002-6009-9845, Haybaeck, J. ORCID logoORCID: https://orcid.org/0000-0001-5518-3359, Robine, S. ORCID logoORCID: https://orcid.org/0000-0002-8885-0389, Louvard, D. ORCID logoORCID: https://orcid.org/0000-0001-5956-7755, Regenbrecht, C. ORCID logoORCID: https://orcid.org/0000-0001-9494-5977, Sporbert, A. ORCID logoORCID: https://orcid.org/0000-0002-3738-1295, Sauer, S. ORCID logoORCID: https://orcid.org/0000-0002-4794-3693, von Eyss, B. ORCID logoORCID: https://orcid.org/0000-0002-4731-6841, Sigal, M. ORCID logoORCID: https://orcid.org/0000-0003-4772-0761 and Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 118 (22): e2019699118. 1 June 2021

Reconstitution of β-adrenergic regulation of Ca(V)1.2: Rad-dependent and Rad-independent protein kinase A mechanisms.
Katz, M. ORCID logoORCID: https://orcid.org/0000-0002-0327-3026, Subramaniam, S. ORCID logoORCID: https://orcid.org/0000-0001-9574-2100, Chomsky-Hecht, O., Tsemakhovich, V. ORCID logoORCID: https://orcid.org/0000-0002-4969-6497, Flockerzi, V., Klussmann, E. ORCID logoORCID: https://orcid.org/0000-0003-4004-5003, Hirsch, J.A. ORCID logoORCID: https://orcid.org/0000-0001-7544-8668, Weiss, S. ORCID logoORCID: https://orcid.org/0000-0002-0981-6917 and Dascal, N. ORCID logoORCID: https://orcid.org/0000-0002-5397-4146
Proceedings of the National Academy of Sciences of the United States of America 118 (21): e2100021118. 17 May 2021

Enhanced Ca(2+) signaling, mild primary aldosteronism, and hypertension in a familial hyperaldosteronism mouse model (Cacna1h(M1560V/+)).
Seidel, E. ORCID logoORCID: https://orcid.org/0000-0003-3334-3950, Schewe, J. ORCID logoORCID: https://orcid.org/0000-0002-7691-4533, Zhang, J. ORCID logoORCID: https://orcid.org/0000-0003-0049-8032, Dinh, H.A. ORCID logoORCID: https://orcid.org/0000-0002-7367-997X, Forslund, S.K. ORCID logoORCID: https://orcid.org/0000-0003-4285-6993, Markó, L. ORCID logoORCID: https://orcid.org/0000-0003-1888-5575, Hellmig, N., Peters, J., Muller, D.N. ORCID logoORCID: https://orcid.org/0000-0003-3650-5644, Lifton, R.P., Nottoli, T. ORCID logoORCID: https://orcid.org/0000-0002-2218-5590, Stölting, G. ORCID logoORCID: https://orcid.org/0000-0002-2339-0545 and Scholl, U.I. ORCID logoORCID: https://orcid.org/0000-0002-0309-8045
Proceedings of the National Academy of Sciences of the United States of America 118 (17): e2014876118. 27 April 2021

DNA origami demonstrate the unique stimulatory power of single pMHCs as T cell antigens.
Hellmeier, J. ORCID logoORCID: https://orcid.org/0000-0002-7153-9121, Platzer, R., Eklund, A.S. ORCID logoORCID: https://orcid.org/0000-0003-1047-2100, Schlichthaerle, T. ORCID logoORCID: https://orcid.org/0000-0003-4444-2575, Karner, A., Motsch, V. ORCID logoORCID: https://orcid.org/0000-0002-4860-4247, Schneider, M.C. ORCID logoORCID: https://orcid.org/0000-0002-3771-8353, Kurz, E., Bamieh, V., Brameshuber, M. ORCID logoORCID: https://orcid.org/0000-0001-8672-2255, Preiner, J. ORCID logoORCID: https://orcid.org/0000-0002-6755-6543, Jungmann, R. ORCID logoORCID: https://orcid.org/0000-0003-4607-3312, Stockinger, H. ORCID logoORCID: https://orcid.org/0000-0001-6404-4430, Schütz, G.J. ORCID logoORCID: https://orcid.org/0000-0003-1542-1089, Huppa, J.B. ORCID logoORCID: https://orcid.org/0000-0003-2634-8198 and Sevcsik, E. ORCID logoORCID: https://orcid.org/0000-0002-2155-1675
Proceedings of the National Academy of Sciences of the United States of America 118 (4): e2016857118. 26 January 2021

On the adhesion-velocity relation and length adaptation of motile cells on stepped fibronectin lanes.
Schreiber, C., Amiri, B. ORCID logoORCID: https://orcid.org/0000-0001-6824-2741, Heyn, J.C.J. ORCID logoORCID: https://orcid.org/0000-0003-0149-4519, Rädler, J.O. ORCID logoORCID: https://orcid.org/0000-0002-5846-1489 and Falcke, M. ORCID logoORCID: https://orcid.org/0000-0001-7137-1114
Proceedings of the National Academy of Sciences of the United States of America 118 (4): e2009959118. 26 January 2021

A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions.
Rodríguez de los Santos, M. ORCID logoORCID: https://orcid.org/0000-0002-2126-7658, Rivalan, M. ORCID logoORCID: https://orcid.org/0000-0002-1642-7522, David, F.S. ORCID logoORCID: https://orcid.org/0000-0001-9521-5669, Stumpf, A. ORCID logoORCID: https://orcid.org/0000-0002-1510-6970, Pitsch, J., Tsortouktzidis, D. ORCID logoORCID: https://orcid.org/0000-0003-3753-7373, Velasquez, L.M., Voigt, A., Schilling, K., Mattei, D. ORCID logoORCID: https://orcid.org/0000-0001-6221-9321, Long, M., Vogt, G. ORCID logoORCID: https://orcid.org/0000-0002-7475-2972, Knaus, A. ORCID logoORCID: https://orcid.org/0000-0003-0366-0533, Fischer-Zirnsak, B. ORCID logoORCID: https://orcid.org/0000-0002-1075-7571, Wittler, L. ORCID logoORCID: https://orcid.org/0000-0001-7873-6702, Timmermann, B., Robinson, P.N., Horn, D. ORCID logoORCID: https://orcid.org/0000-0003-0870-8911, Mundlos, S., Kornak, U., Becker, A.J., Schmitz, D. ORCID logoORCID: https://orcid.org/0000-0003-2741-5241, Winter, Y. ORCID logoORCID: https://orcid.org/0000-0002-7828-1872 and Krawitz, P.M. ORCID logoORCID: https://orcid.org/0000-0002-3194-8625
Proceedings of the National Academy of Sciences of the United States of America 118 (2): e2014481118. 12 January 2021

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
Ostkamp, P., Salmen, A. ORCID logoORCID: https://orcid.org/0000-0002-4751-299X, Pignolet, B., Görlich, D. ORCID logoORCID: https://orcid.org/0000-0002-2574-9419, Andlauer, T.F.M. ORCID logoORCID: https://orcid.org/0000-0002-2917-5889, Schulte-Mecklenbeck, A. ORCID logoORCID: https://orcid.org/0000-0003-3855-4706, Gonzalez-Escamilla, G. ORCID logoORCID: https://orcid.org/0000-0002-7209-1736, Bucciarelli, F., Gennero, I. ORCID logoORCID: https://orcid.org/0000-0002-8572-7852, Breuer, J., Antony, G. ORCID logoORCID: https://orcid.org/0000-0002-5367-6069, Schneider-Hohendorf, T. ORCID logoORCID: https://orcid.org/0000-0002-3717-5176, Mykicki, N., Bayas, A., Then Bergh, F., Bittner, S. ORCID logoORCID: https://orcid.org/0000-0003-2179-3655, Hartung, H.P., Friese, M.A. ORCID logoORCID: https://orcid.org/0000-0001-6380-2420, Linker, R.A., Luessi, F. ORCID logoORCID: https://orcid.org/0000-0003-4334-4199, Lehmann-Horn, K., Mühlau, M. ORCID logoORCID: https://orcid.org/0000-0002-9545-2709, Paul, F. ORCID logoORCID: https://orcid.org/0000-0002-6378-0070, Stangel, M. ORCID logoORCID: https://orcid.org/0000-0003-2504-5398, Tackenberg, B., Tumani, H. ORCID logoORCID: https://orcid.org/0000-0002-1647-6201, Warnke, C. ORCID logoORCID: https://orcid.org/0000-0002-3510-9255, Weber, F., Wildemann, B., Zettl, U.K. ORCID logoORCID: https://orcid.org/0000-0002-6348-1759, Ziemann, U. ORCID logoORCID: https://orcid.org/0000-0001-8372-3615, Müller-Myhsok, B. ORCID logoORCID: https://orcid.org/0000-0002-0719-101X, Kümpfel, T. ORCID logoORCID: https://orcid.org/0000-0001-7509-5268, Klotz, L., Meuth, S.G. ORCID logoORCID: https://orcid.org/0000-0003-2571-3501, Zipp, F. ORCID logoORCID: https://orcid.org/0000-0002-1231-1928, Hemmer, B. ORCID logoORCID: https://orcid.org/0000-0001-5985-6784, Hohlfeld, R. ORCID logoORCID: https://orcid.org/0000-0002-6302-1488, Brassat, D., Gold, R., Gross, C.C., Lukas, C. ORCID logoORCID: https://orcid.org/0000-0002-8562-9697, Groppa, S., Loser, K., Wiendl, H. and Schwab, N. ORCID logoORCID: https://orcid.org/0000-0001-5494-9885
Proceedings of the National Academy of Sciences of the United States of America 118 (1): e2018457118. 5 January 2021

2020

Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Barone, M. ORCID logoORCID: https://orcid.org/0000-0002-6554-6464, Müller, M., Chiha, S., Ren, J., Albat, D., Soicke, A., Dohmen, S., Klein, M., Bruns, J., van Dinther, M., Opitz, R. ORCID logoORCID: https://orcid.org/0000-0003-3143-0997, Lindemann, P. ORCID logoORCID: https://orcid.org/0000-0002-8224-3764, Beerbaum, M., Motzny, K., Roske, Y. ORCID logoORCID: https://orcid.org/0000-0001-6237-388X, Schmieder, P. ORCID logoORCID: https://orcid.org/0000-0001-9968-9327, Volkmer, R., Nazaré, M. ORCID logoORCID: https://orcid.org/0000-0002-1602-2330, Heinemann, U. ORCID logoORCID: https://orcid.org/0000-0002-8191-3850, Oschkinat, H., Ten Dijke, P., Schmalz, H.G. ORCID logoORCID: https://orcid.org/0000-0003-0489-1827 and Kühne, R.
Proceedings of the National Academy of Sciences of the United States of America 117 (47): 29684-29690. 24 November 2020

Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists.
Işbilir, A. ORCID logoORCID: https://orcid.org/0000-0002-9629-1150, Möller, J. ORCID logoORCID: https://orcid.org/0000-0001-8429-3784, Arimont, M. ORCID logoORCID: https://orcid.org/0000-0002-9367-5298, Bobkov, V. ORCID logoORCID: https://orcid.org/0000-0002-5414-8188, Perpiñá-Viciano, C. ORCID logoORCID: https://orcid.org/0000-0003-4647-1521, Hoffmann, C. ORCID logoORCID: https://orcid.org/0000-0003-0884-9300, Inoue, A., Heukers, R., de Graaf, C. ORCID logoORCID: https://orcid.org/0000-0002-1226-2150, Smit, M.J. ORCID logoORCID: https://orcid.org/0000-0003-2713-0238, Annibale, P. ORCID logoORCID: https://orcid.org/0000-0003-3208-5347 and Lohse, M.J. ORCID logoORCID: https://orcid.org/0000-0002-0599-3510
Proceedings of the National Academy of Sciences of the United States of America 117 (46): 29144-29154. 17 November 2020

The transcription factor C/EBPβ orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions.
Scholz, F. ORCID logoORCID: https://orcid.org/0000-0002-0253-081X, Grau, M., Menzel, L. ORCID logoORCID: https://orcid.org/0000-0002-3816-6255, Graband, A. ORCID logoORCID: https://orcid.org/0000-0002-9038-0734, Zapukhlyak, M. ORCID logoORCID: https://orcid.org/0000-0002-2635-6940, Leutz, A. ORCID logoORCID: https://orcid.org/0000-0001-8259-927X, Janz, M. ORCID logoORCID: https://orcid.org/0000-0002-1127-0044, Lenz, G., Rehm, A. ORCID logoORCID: https://orcid.org/0000-0001-7490-1950 and Höpken, U.E. ORCID logoORCID: https://orcid.org/0000-0002-0776-4893
Proceedings of the National Academy of Sciences of the United States of America 117 (42): 26328-26339. 20 October 2020

Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis.
Sommermann, T. ORCID logoORCID: https://orcid.org/0000-0003-2899-0256, Yasuda, T. ORCID logoORCID: https://orcid.org/0000-0001-9997-6852, Ronen, J. ORCID logoORCID: https://orcid.org/0000-0003-3980-6469, Wirtz, T. ORCID logoORCID: https://orcid.org/0009-0005-5677-9804, Weber, T. ORCID logoORCID: https://orcid.org/0000-0003-2079-842X, Sack, U., Caeser, R., Zhang, J., Li, X. ORCID logoORCID: https://orcid.org/0000-0002-1173-1066, Chu, V.T. ORCID logoORCID: https://orcid.org/0000-0003-1327-8696, Jauch, A., Unger, K., Hodson, D.J. ORCID logoORCID: https://orcid.org/0000-0001-6225-2033, Akalin, A. ORCID logoORCID: https://orcid.org/0000-0002-0468-0117 and Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370
Proceedings of the National Academy of Sciences of the United States of America 117 (25): 14421-14432. 23 June 2020

EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake.
Matthaeus, C. ORCID logoORCID: https://orcid.org/0000-0003-3242-1195, Lahmann, I. ORCID logoORCID: https://orcid.org/0000-0003-0640-4519, Kunz, S. ORCID logoORCID: https://orcid.org/0000-0002-0131-3506, Jonas, W., Melo, A.A., Lehmann, M., Larsson, E., Lundmark, R., Kern, M., Blüher, M., Olschowski, H., Kompa, J., Brügger, B., Müller, D.N. ORCID logoORCID: https://orcid.org/0000-0003-3650-5644, Haucke, V. ORCID logoORCID: https://orcid.org/0000-0003-3119-6993, Schürmann, A. ORCID logoORCID: https://orcid.org/0000-0002-4113-4377, Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872 and Daumke, O. ORCID logoORCID: https://orcid.org/0000-0002-6190-1414
Proceedings of the National Academy of Sciences of the United States of America 117 (13): 7471-7481. 31 March 2020

Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice.
Wenzel, J. ORCID logoORCID: https://orcid.org/0000-0001-6313-2439, Hansen, C.E., Bettoni, C., Vogt, M.A., Lembrich, B., Natsagdorj, R., Huber, G., Brands, J., Schmidt, K., Assmann, J.C., Stölting, I., Saar, K. ORCID logoORCID: https://orcid.org/0000-0002-4483-1557, Sedlacik, J., Fiehler, J., Ludewig, P., Wegmann, M., Feller, N., Richter, M. ORCID logoORCID: https://orcid.org/0000-0003-4178-6866, Müller-Fielitz, H., Walther, T., König, G.M., Kostenis, E. ORCID logoORCID: https://orcid.org/0000-0001-8284-5514, Raasch, W., Hübner, N. ORCID logoORCID: https://orcid.org/0000-0002-1218-6223, Gass, P., Offermanns, S., de Wit, C., Wagner, C.A. ORCID logoORCID: https://orcid.org/0000-0002-9874-8898 and Schwaninger, M. ORCID logoORCID: https://orcid.org/0000-0002-4510-9718
Proceedings of the National Academy of Sciences of the United States of America 117 (3): 1753-1761. 21 January 2020

2019

Resolving titin's lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes.
Rudolph, F., Hüttemeister, J., da Silva Lopes, K., Jüttner, R. ORCID logoORCID: https://orcid.org/0000-0003-3565-0698, Yu, L., Bergmann, N., Friedrich, D. ORCID logoORCID: https://orcid.org/0000-0003-2144-9280, Preibisch, S. ORCID logoORCID: https://orcid.org/0000-0002-0276-494X, Wagner, E., Lehnart, S.E. ORCID logoORCID: https://orcid.org/0000-0002-8115-3513, Gregorio, C.C. and Gotthardt, M. ORCID logoORCID: https://orcid.org/0000-0003-1788-3172
Proceedings of the National Academy of Sciences of the United States of America 116 (50): 25126-25136. 10 December 2019

Human-specific tandem repeat expansion and differential gene expression during primate evolution.
Sulovari, A. ORCID logoORCID: https://orcid.org/0000-0003-4354-9020, Li, R., Audano, P.A., Porubsky, D., Vollger, M.R., Logsdon, G.A., Warren, W.C., Pollen, A.A. ORCID logoORCID: https://orcid.org/0000-0003-3263-8634, Chaisson, M.J.P. and Eichler, E.E. ORCID logoORCID: https://orcid.org/0000-0002-8246-4014
Proceedings of the National Academy of Sciences of the United States of America 116 (46): 23243-23253. 12 November 2019

Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger, K.J. ORCID logoORCID: https://orcid.org/0000-0003-1139-3308, Neukam, M., Tattikota, S.G. ORCID logoORCID: https://orcid.org/0000-0003-0318-5533, Qadri, F. ORCID logoORCID: https://orcid.org/0000-0002-8500-489X, Puchkov, D., Willmes, D.M., Wurmsee, S., Geisberger, S. ORCID logoORCID: https://orcid.org/0000-0001-6477-1312, Dechend, R. ORCID logoORCID: https://orcid.org/0000-0001-6636-3080, Raile, K. ORCID logoORCID: https://orcid.org/0000-0002-0842-1737, Kurth, T., Nguyen, G., Poy, M.N. ORCID logoORCID: https://orcid.org/0000-0002-4904-2426, Solimena, M., Muller, D.N. ORCID logoORCID: https://orcid.org/0000-0003-3650-5644 and Birkenfeld, A.L.
Proceedings of the National Academy of Sciences of the United States of America 116 (40): 19983-19988. 1 October 2019

How drag sharpens a T cell's view on antigen.
Schütz, G.J. ORCID logoORCID: https://orcid.org/0000-0003-1542-1089 and Huppa, J.B. ORCID logoORCID: https://orcid.org/0000-0003-2634-8198
Proceedings of the National Academy of Sciences of the United States of America 116 (34): 16669-16671. 20 August 2019

Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.
Omar, F., Findlay, J.E., Carfray, G., Allcock, R.W., Jiang, Z., Moore, C., Muir, A.L., Lannoy, M., Fertig, B.A., Mai, D., Day, J.P., Bolger, G., Baillie, G.S. ORCID logoORCID: https://orcid.org/0000-0003-2469-6316, Schwiebert, E., Klussmann, E. ORCID logoORCID: https://orcid.org/0000-0003-4004-5003, Pyne, N.J., Ong, A.C.M. ORCID logoORCID: https://orcid.org/0000-0002-7211-5400, Bowers, K., Adam, J.M., Adams, D.R., Houslay, M.D. and Henderson, D.J.P.
Proceedings of the National Academy of Sciences of the United States of America 116 (27): 13320-13329. 2 July 2019

Preformed chromatin topology assists transcriptional robustness of Shh during limb development.
Paliou, C. ORCID logoORCID: https://orcid.org/0000-0003-3383-2527, Guckelberger, P., Schöpflin, R., Heinrich, V., Esposito, A. ORCID logoORCID: https://orcid.org/0000-0002-5903-8439, Chiariello, A.M. ORCID logoORCID: https://orcid.org/0000-0002-6112-0167, Bianco, S. ORCID logoORCID: https://orcid.org/0000-0001-5819-060X, Annunziatella, C., Helmuth, J., Haas, S., Jerković, I., Brieske, N., Wittler, L., Timmermann, B., Nicodemi, M. ORCID logoORCID: https://orcid.org/0000-0002-8416-6416, Vingron, M., Mundlos, S. and Andrey, G.
Proceedings of the National Academy of Sciences of the United States of America 116 (25): 12390-12399. 18 June 2019

Insights into IgM-mediated complement activation based on in situ structures of IgM-C1-C4b.
Sharp, T.H. ORCID logoORCID: https://orcid.org/0000-0002-1990-2333, Boyle, A.L. ORCID logoORCID: https://orcid.org/0000-0003-4176-6080, Diebolder, C.A. ORCID logoORCID: https://orcid.org/0000-0001-7694-7362, Kros, A. ORCID logoORCID: https://orcid.org/0000-0002-3983-3048, Koster, A. ORCID logoORCID: https://orcid.org/0000-0003-1717-2549 and Gros, P. ORCID logoORCID: https://orcid.org/0000-0002-7782-2585
Proceedings of the National Academy of Sciences of the United States of America 116 (24): 11900-11905. 11 June 2019

Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement.
Grushevskyi, E.O. ORCID logoORCID: https://orcid.org/0000-0003-1779-8306, Kukaj, T., Schmauder, R., Bock, A. ORCID logoORCID: https://orcid.org/0000-0002-6344-6494, Zabel, U., Schwabe, T., Benndorf, K. and Lohse, M.J. ORCID logoORCID: https://orcid.org/0000-0002-0599-3510
Proceedings of the National Academy of Sciences of the United States of America 116 (20): 10150-10155. 14 May 2019

MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis.
Kotelnikova, E., Kiani, N.A., Messinis, D., Pertsovskaya, I., Pliaka, V., Bernardo-Faura, M., Rinas, M., Vila, G., Zubizarreta, I., Pulido-Valdeolivas, I., Sakellaropoulos, T., Faigle, W., Silberberg, G., Masso, M., Stridh, P., Behrens, J., Olsson, T., Martin, R., Paul, F. ORCID logoORCID: https://orcid.org/0000-0002-6378-0070, Alexopoulos, L.G., Saez-Rodriguez, J., Tegner, J. and Villoslada, P.
Proceedings of the National Academy of Sciences of the United States of America 116 (19): 9671-9676. 7 May 2019

2018

Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice.
Hernandez-Miranda, L.R. ORCID logoORCID: https://orcid.org/0000-0002-0498-708X, Ibrahim, D.M., Ruffault, P.L. ORCID logoORCID: https://orcid.org/0000-0002-3378-3828, Larrosa, M., Balueva, K., Müller, T. ORCID logoORCID: https://orcid.org/0000-0001-8096-1853, de Weerd, W., Stolte-Dijkstra, I., Hostra, R.M.W., Brunet, J.F. ORCID logoORCID: https://orcid.org/0000-0002-1985-6103, Fortin, G., Mundlos, S. and Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 115 (51): 13021-13026. 18 December 2018

Atomistic simulations indicate the functional loop-to-coiled-coil transition in influenza hemagglutinin is not downhill.
Lin, X., Noel, J.K. ORCID logoORCID: https://orcid.org/0000-0003-3168-6036, Wang, Q., Ma, J. and Onuchic, J.N.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): E7905-E7913. 21 August 2018

Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion.
Löber, U. ORCID logoORCID: https://orcid.org/0000-0001-7468-9531, Hobbs, M., Dayaram, A., Tsangaras, K., Jones, K., Alquezar-Planas, D.E., Ishida, Y., Meers, J., Mayer, J., Quedenau, C. ORCID logoORCID: https://orcid.org/0000-0002-6846-4915, Chen, W. ORCID logoORCID: https://orcid.org/0000-0003-3263-1627, Johnson, R.N., Timms, P., Young, P.R., Roca, A.L. and Greenwood, A.D.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): 8609-8614. 21 August 2018

Structural changes of TasA in biofilm formation of Bacillus subtilis.
Diehl, A., Roske, Y. ORCID logoORCID: https://orcid.org/0000-0001-6237-388X, Ball, L., Chowdhury, A., Hiller, M., Molière, N., Kramer, R., Stöppler, D., Worth, C.L. ORCID logoORCID: https://orcid.org/0000-0002-1796-9606, Schlegel, B., Leidert, M., Cremer, N., Erdmann, N., Lopez, D., Stephanowitz, H., Krause, E., van Rossum, B.J., Schmieder, P. ORCID logoORCID: https://orcid.org/0000-0001-9968-9327, Heinemann, U. ORCID logoORCID: https://orcid.org/0000-0002-8191-3850, Turgay, K., Akbey, Ü. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 115 (13): 3237-3242. 27 March 2018

Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3.
Sowa, A.S., Martin, E., Martins, I.M., Schmidt, J., Depping, R., Weber, J.J., Rother, F. ORCID logoORCID: https://orcid.org/0000-0002-4417-2192, Hartmann, E., Bader, M. ORCID logoORCID: https://orcid.org/0000-0003-4780-4164, Riess, O., Tricoire, H. and Schmidt, T.
Proceedings of the National Academy of Sciences of the United States of America 115 (11): E2624-E2633. 13 March 2018

Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4(+) and CD8(+) T cell responses.
Choi, I.K., Wang, Z., Ke, Q., Hong, M., Qian, Y., Zhao, X., Liu, Y., Kim, H.J., Ritz, J., Cantor, H., Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370, Wucherpfennig, K.W. and Zhang, B.
Proceedings of the National Academy of Sciences of the United States of America 115 (4): E686-E695. January 2018

2017

Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest.
Espinosa-Medina, I., Jevans, B., Boismoreau, F., Chettouh, Z., Enomoto, H., Müller, T. ORCID logoORCID: https://orcid.org/0000-0001-8096-1853, Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872, Burns, Alan J and Brunet, J.F. ORCID logoORCID: https://orcid.org/0000-0002-1985-6103
Proceedings of the National Academy of Sciences of the United States of America 114 (45): 11980-11985. 7 November 2017

Necroptosis controls NET generation and mediates complement activation, endothelial damage, and autoimmune vasculitis.
Schreiber, A. ORCID logoORCID: https://orcid.org/0000-0003-1244-6379, Rousselle, A. ORCID logoORCID: https://orcid.org/0000-0002-0641-3143, Becker, J.U., von Mässenhausen, A., Linkermann, A. and Kettritz, R. ORCID logoORCID: https://orcid.org/0000-0001-5821-6718
Proceedings of the National Academy of Sciences of the United States of America 114 (45): E9618-E9625. 7 November 2017

Identification of individuals by trait prediction using whole-genome sequencing data.
Lippert, C. ORCID logoORCID: https://orcid.org/0000-0001-6363-2556, Sabatini, R., Maher, M.C., Kang, E.Y., Lee, S., Arikan, O., Harley, A., Bernal, A., Garst, P., Lavrenko, V., Yocum, K., Wong, T., Zhu, M., Yang, W.Y., Chang, C., Lu, T., Lee, C.W.H., Hicks, B., Ramakrishnan, S., Tang, H., Xie, C., Piper, J., Brewerton, S., Turpaz, Y., Telenti, A., Roby, R.K., Och, F.J. and Venter, J.C.
Proceedings of the National Academy of Sciences of the United States of America 114 (38): 10166-10171. 19 September 2017

Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.
Hasegawa, E., Inafuku, S., Mulki, L., Okunuki, Y., Yanai, R., Smith, K.E., Kim, C.B., Klokman, G., Bielenberg, D.R., Puli, N., Falck, J.R., Husain, D., Miller, J.W., Edin, M.L., Zeldin, D.C., Lee, K.S.S., Hammock, B.D., Schunck, W.H. ORCID logoORCID: https://orcid.org/0000-0001-7965-7731 and Connor, K.M.
Proceedings of the National Academy of Sciences of the United States of America 114 (36): E7545-E7553. 5 September 2017

Genetic identification of a hindbrain nucleus essential for innate vocalization.
Hernandez-Miranda, L.R. ORCID logoORCID: https://orcid.org/0000-0002-0498-708X, Ruffault, P.L. ORCID logoORCID: https://orcid.org/0000-0002-3378-3828, Bouvier, J.C., Murray, A.J., Morin-Surun, M.P., Zampieri, N. ORCID logoORCID: https://orcid.org/0000-0002-2228-9453, Cholewa-Waclaw, J.B. ORCID logoORCID: https://orcid.org/0000-0001-8625-8528, Ey, E., Brunet, J.F., Champagnat, J., Fortin, G. and Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 114 (30): 8095-8100. 25 July 2017

Structural insights into the activation mechanism of dynamin-like EHD ATPases.
Melo, A.A., Hegde, B.G., Shah, C., Larsson, E., Isas, J.M., Kunz, S. ORCID logoORCID: https://orcid.org/0000-0002-0131-3506, Lundmark, R., Langen, R. and Daumke, O. ORCID logoORCID: https://orcid.org/0000-0002-6190-1414
Proceedings of the National Academy of Sciences of the United States of America 114 (22): 5629-5634. 30 May 2017

Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.
Tobe, B.T.D., Crain, A.M., Winquist, A.M., Calabrese, B., Makihara, H., Zhao, W.N., Lalonde, J., Nakamura, H., Konopaske, G., Sidor, M., Pernia, C.D., Yamashita, N., Wada, M., Inoue, Y., Nakamura, F., Sheridan, S.D., Logan, R.W., Brandel, M., Wu, D., Hunsberger, J., Dorsett, L., Duerr, C., Basa, R.C.B., McCarthy, M.J., Udeshi, N.D., Mertins, P. ORCID logoORCID: https://orcid.org/0000-0002-2245-528X, Carr, S.A., Rouleau, G.A., Mastrangelo, L., Li, J., Gutierrez, G.J., Brill, L.M., Venizelos, N., Chen, G., Nye, J.S., Manji, H., Price, J.H., McClung, C.A., Akiskal, H.S., Alda, M., Chuang, D.M.M., Coyle, J.T., Liu, Y., Teng, Y.D., Ohshima, T., Mikoshiba, K., Sidman, R.L., Halpain, S., Haggarty, S.J., Goshima, Y. and Snyder, E.Y.
Proceedings of the National Academy of Sciences of the United States of America 114 (22): E4462-E4471. 30 May 2017

Data-based modeling of drug penetration relates human skin barrier function to the interplay of diffusivity and free-energy profiles.
Schulz, R., Yamamoto, K., Klossek, A., Flesch, R., Hönzke, S., Rancan, F., Vogt, A., Blume-Peytavi, U., Hedtrich, S. ORCID logoORCID: https://orcid.org/0000-0001-6770-3657, Schäfer-Korting, M., Rühl, E. and Netz, R.R.
Proceedings of the National Academy of Sciences of the United States of America 114 (14): 3631-3636. 4 April 2017

George Klein: 1925-2016.
Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370
National Academy of Sciences. 28 March 2017

2016

Role of the receptor Mas in macrophage-mediated inflammation in vivo.
Hammer, A., Yang, G., Friedrich, J., Kovacs, A., Lee, D.H., Grave, K., Jörg, S., Alenina, N. ORCID logoORCID: https://orcid.org/0000-0002-6071-5433, Grosch, J., Winkler, J., Gold, R., Bader, M. ORCID logoORCID: https://orcid.org/0000-0003-4780-4164, Manzel, A., Rump, L.C., Müller, D.N. ORCID logoORCID: https://orcid.org/0000-0003-3650-5644, Linker, R.A. and Stegbauer, J.
Proceedings of the National Academy of Sciences of the United States of America 113 (49): 14109-14114. 6 December 2016

Mouse model for acute Epstein-Barr virus infection.
Wirtz, T. ORCID logoORCID: https://orcid.org/0009-0005-5677-9804, Weber, T. ORCID logoORCID: https://orcid.org/0000-0003-2079-842X, Kracker, S., Sommermann, T. ORCID logoORCID: https://orcid.org/0000-0003-2899-0256, Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370 and Yasuda, T. ORCID logoORCID: https://orcid.org/0000-0001-9997-6852
Proceedings of the National Academy of Sciences of the United States of America 113 (48): 13821-13826. 29 November 2016

Stress-induced brain activity, brain atrophy, and clinical disability in multiple sclerosis.
Weygandt, M. ORCID logoORCID: https://orcid.org/0000-0001-9962-4582, Meyer-Arndt, L. ORCID logoORCID: https://orcid.org/0000-0002-7909-020X, Behrens, J.R., Wakonig, K., Bellmann-Strobl, J. ORCID logoORCID: https://orcid.org/0000-0003-2615-1643, Ritter, K., Scheel, M., Brandt, A.U. ORCID logoORCID: https://orcid.org/0000-0002-9768-014X, Labadie, C., Hetzer, S., Gold, S.M., Paul, F. ORCID logoORCID: https://orcid.org/0000-0002-6378-0070 and Haynes, J.D.
Proceedings of the National Academy of Sciences of the United States of America 113 (47): 13444-13449. 22 November 2016

Super-resolution ribosome profiling reveals unannotated translation events in Arabidopsis.
Hsu, P.Y., Calviello, L. ORCID logoORCID: https://orcid.org/0000-0002-5600-0988, Wu, H.Y.L., Li, F.W., Rothfels, C.J., Ohler, U. ORCID logoORCID: https://orcid.org/0000-0002-0881-3116 and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 113 (45): E7126-E7135. 8 November 2016

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.
Chu, V.T. ORCID logoORCID: https://orcid.org/0000-0003-1327-8696, Graf, R. ORCID logoORCID: https://orcid.org/0000-0002-5400-9938, Wirtz, T. ORCID logoORCID: https://orcid.org/0009-0005-5677-9804, Weber, T. ORCID logoORCID: https://orcid.org/0000-0003-2079-842X, Favret, J., Li, X. ORCID logoORCID: https://orcid.org/0000-0002-1173-1066, Petsch, K., Tran, N.T. ORCID logoORCID: https://orcid.org/0000-0003-0896-8641, Sieweke, M.H. ORCID logoORCID: https://orcid.org/0000-0002-3228-9537, Berek, C., Kühn, R. ORCID logoORCID: https://orcid.org/0000-0003-1694-9803 and Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370
Proceedings of the National Academy of Sciences of the United States of America 113 (44): 12514-12519. 1 November 2016

RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.
Grauel, M.K., Maglione, M., Reddy-Alla, S., Willmes, C.G., Brockmann, M.M., Trimbuch, T. ORCID logoORCID: https://orcid.org/0000-0001-7512-8955, Rosenmund, T., Pangalos, M., Vardar, G., Stumpf, A., Walter, A.M., Rost, B.R., Eickholt, B.J., Haucke, V., Schmitz, D. ORCID logoORCID: https://orcid.org/0000-0003-2741-5241, Sigrist, S.J. and Rosenmund, C.
Proceedings of the National Academy of Sciences of the United States of America 113 (41): 11615-11620. 11 October 2016

Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination.
Braten, O., Livneh, I., Ziv, T., Admon, A., Kehat, I., Caspi, L.H., Gonen, H., Bercovich, B., Godzik, A., Jahandideh, S., Jaroszewski, L., Sommer, T. ORCID logoORCID: https://orcid.org/0000-0001-9990-5202, Kwon, Y.T., Guharoy, M., Tompa, P. and Ciechanover, A.
Proceedings of the National Academy of Sciences of the United States of America 113 (32): E4639-E4647. 9 August 2016

Superpriming of synaptic vesicles as a common basis for intersynapse variability and modulation of synaptic strength.
Taschenberger, H., Woehler, A. ORCID logoORCID: https://orcid.org/0000-0001-5157-9313 and Neher, E.
Proceedings of the National Academy of Sciences of the United States of America 113 (31): E4548-E4557. 2 August 2016

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E. ORCID logoORCID: https://orcid.org/0000-0003-1421-4045, Herzog, S., Labi, V. ORCID logoORCID: https://orcid.org/0000-0001-7538-1520, Yasuda, T. ORCID logoORCID: https://orcid.org/0000-0001-9997-6852, Köchert, K. ORCID logoORCID: https://orcid.org/0000-0002-5548-2022, Janz, M. ORCID logoORCID: https://orcid.org/0000-0002-1127-0044, Villunger, A., Schmidt-Supprian, M. and Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5065-5070. 3 May 2016

Tissue-specific DNA demethylation is required for proper B-cell differentiation and function.
Orlanski, S., Labi, V. ORCID logoORCID: https://orcid.org/0000-0001-7538-1520, Reizel, Y., Spiro, A., Lichtenstein, M., Levin-Klein, R., Koralov, S.B., Skversky, Y., Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370, Cedar, H. and Bergman, Y.
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5018-5023. 3 May 2016

Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders.
Wakabayashi, A., Ulirsch, J.C., Ludwig, L.S. ORCID logoORCID: https://orcid.org/0000-0002-2916-2164, Fiorini, C., Yasuda, M., Choudhuri, A., McDonel, P., Zon, L.I. and Sankaran, V.G.
Proceedings of the National Academy of Sciences of the United States of America 113 (16): 4434-4439. 19 April 2016

Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections.
Cano, E. ORCID logoORCID: https://orcid.org/0000-0003-1091-8934, Carmona, R., Ruiz-Villalba, A., Rojas, A., Chau, Y.Y., Wagner, K.D., Wagner, N., Hastie, N.D., Munoz-Chapuli, R. and Perez-Pomares, J.M.
Proceedings of the National Academy of Sciences of the United States of America 113 (3): 656-661. 19 January 2016

2015

The B-cell antigen receptor integrates adaptive and innate immune signals.
Otipoby, K.L., Waisman, A., Derudder, E. ORCID logoORCID: https://orcid.org/0000-0003-1421-4045, Srinivasan, L., Franklin, A. and Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370
Proceedings of the National Academy of Sciences of the United States of America 112 (39): 12145-12150. 29 September 2015

A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.
Opitz, R. ORCID logoORCID: https://orcid.org/0000-0003-3143-0997, Mueller, M., Reuter, C., Barone, M. ORCID logoORCID: https://orcid.org/0000-0002-6554-6464, Soicke, A., Roske, Y. ORCID logoORCID: https://orcid.org/0000-0001-6237-388X, Piotukh, K., Huy, P., Beerbaum, M., Wiesner, B., Beyermann, M., Schmieder, P. ORCID logoORCID: https://orcid.org/0000-0001-9968-9327, Freund, C., Volkmer, R., Oschkinat, H., Schmalz, H.G. and Kuehne, R.
Proceedings of the National Academy of Sciences of the United States of America 112 (16): 5011-5016. 21 April 2015

VH replacement in primary immunoglobulin repertoire diversification.
Sun, A., Novobrantseva, T.I., Coffre, M., Hewitt, S.L., Jensen, K., Skok, J.A., Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370 and Koralov, S.B.
Proceedings of the National Academy of Sciences of the United States of America 112 (5): E458-E466. 3 February 2015

2014

Essential role for autophagy during invariant NKT cell development.
Salio, M., Puleston, D.J., Mathan, T.S.M., Shepherd, D., Stranks, A.J., Adamopoulou, E., Veerapen, N., Besra, G.S., Hollander, G.A., Simon, A.K. ORCID logoORCID: https://orcid.org/0000-0002-4077-7995 and Cerundolo, V.
Proceedings of the National Academy of Sciences of the United States of America 111 (52): E5678-E5687. 30 December 2014

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, S., Bouhlel, M.A., Cauchy, P., Lamprecht, B., Li, S., Grau, M., Hummel, F., Köchert, K. ORCID logoORCID: https://orcid.org/0000-0002-5548-2022, Anagnostopoulos, I., Jöhrens, K., Hummel, M., Hiscott, J., Wenzel, S.S., Lenz, P., Schneider, M., Küppers, R., Scheidereit, C. ORCID logoORCID: https://orcid.org/0000-0002-0446-6129, Giefing, M., Siebert, R., Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370, Lenz, G., Cockerill, P.N., Janz, M. ORCID logoORCID: https://orcid.org/0000-0002-1127-0044, Dörken, B. ORCID logoORCID: https://orcid.org/0000-0001-7991-3643, Bonifer, C. and Mathas, S. ORCID logoORCID: https://orcid.org/0000-0001-9626-1413
Proceedings of the National Academy of Sciences of the United States of America 111 (42): E4513-E4522. 21 October 2014

IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors.
Authier, H., Billot, K., Derudder, E. ORCID logoORCID: https://orcid.org/0000-0003-1421-4045, Bordereaux, D., Riviere, P., Rodrigues-Ferreira, S., Nahmias, C. and Baud, V.
Proceedings of the National Academy of Sciences of the United States of America 111 (41): 14794-14799. 14 October 2014

Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1.
Kayatekin, C., Matlack, K.E.S., Hesse, W.R., Guan, Y., Chakrabortee, S., Russ, J. ORCID logoORCID: https://orcid.org/0000-0001-6550-761X, Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630, Shah, J.V. and Lindquist, S.
Proceedings of the National Academy of Sciences of the United States of America 111 (33): 12085-12090. 19 August 2014

Cytochrome P450-generated metabolites derived from ω-3 fatty acids attenuate neovascularization.
Yanai, R., Mulki, L., Hasegawa, E., Takeuchi, K., Sweigard, H., Suzuki, J., Gaissert, P., Vavvas, D.G., Sonoda, K.H., Rothe, M. ORCID logoORCID: https://orcid.org/0000-0002-6813-4705, Schunck, W.H. ORCID logoORCID: https://orcid.org/0000-0001-7965-7731, Miller, J.W. and Connor, K.M.
Proceedings of the National Academy of Sciences of the United States of America 111 (26): 9603-9608. 1 July 2014

Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.
Heuberger, J. ORCID logoORCID: https://orcid.org/0000-0001-7205-732X, Kosel, F., Qi, J., Grossmann, K.S., Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370 and Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 111 (9): 3472-3477. 4 March 2014

Michael S. Neuberger 1953-2013.
Rajewsky, K. ORCID logoORCID: https://orcid.org/0000-0002-6633-6370
Proceedings of the National Academy of Sciences of the United States of America 111 (8): 2862-2863. 25 February 2014

Clostridium difficile toxin CDT hijacks microtubule organization and reroutes vesicle traffic to increase pathogen adherence.
Schwan, C., Kruppke, A.S., Nölke, T., Schumacher, L., Koch-Nolte, F., Kudryashev, M. ORCID logoORCID: https://orcid.org/0000-0003-3550-6274, Stahlberg, H. and Aktories, K.
Proceedings of the National Academy of Sciences of the United States of America 111 (6): 2313-2318. 11 February 2014

Electroconvulsive therapy-induced brain plasticity determines therapeutic outcome in mood disorders.
Dukart, J., Regen, F., Kherif, F., Colla, M., Bajbouj, M., Heuser, I., Frackowiak, R.S. and Draganski, B.
Proceedings of the National Academy of Sciences of the United States of America 111 (3): 1156-1161. 21 January 2014

2013

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.
Rockich, B.E., Hrycaj, S.M., Shih, H.P., Nagy, M.S., Ferguson, M.A.H., Kopp, J.L., Sander, M. ORCID logoORCID: https://orcid.org/0000-0001-5308-7785, Wellik, D.M. and Spence, J.R.
Proceedings of the National Academy of Sciences of the United States of America 110 (47): E4456-64. 19 November 2013

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T., Stein, S., Qi, J., Wende, H. ORCID logoORCID: https://orcid.org/0000-0002-9168-8095, Garratt, A.N. ORCID logoORCID: https://orcid.org/0000-0001-9631-3041, Nave, K.A., Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872 and Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179. 5 November 2013

Reexposure to nicotine during withdrawal increases the pacemaking activity of cholinergic habenular neurons.
Goerlich, A., Antolin-Fontes, B. ORCID logoORCID: https://orcid.org/0000-0002-5724-0932, Ables, J.L., Frahm, S. ORCID logoORCID: https://orcid.org/0000-0001-5645-2557, Slimak, M.A. ORCID logoORCID: https://orcid.org/0000-0003-3203-2309, Dougherty, J.D. and Ibanez-Tallon, I.
Proceedings of the National Academy of Sciences of the United States of America 110 (42): 17077-17082. 15 October 2013

Using machine learning to identify disease-relevant regulatory RNAs.
Ohler, U. ORCID logoORCID: https://orcid.org/0000-0002-0881-3116
Proceedings of the National Academy of Sciences of the United States of America 110 (39): 15516-15517. 24 September 2013

GABA(B) autoreceptor-mediated cell type-specific reduction of inhibition in epileptic mice.
Dugladze, T., Maziashvili, N., Boergers, C., Gurgenidze, S., Haeussler, U., Winkelmann, A., Haas, C.A., Meier, J.C. ORCID logoORCID: https://orcid.org/0000-0001-5574-3336, Vida, I., Kopell, N.J. and Gloveli, T.
Proceedings of the National Academy of Sciences of the United States of America 110 (37): 15073-15078. 10 September 2013

Neurokinin3 receptor as a target to predict and improve learning and memory in the aged organism.
de Souza Silva, M.A., Lenz, B., Rotter, A., Biermann, T., Peters, O. ORCID logoORCID: https://orcid.org/0000-0003-0568-2998, Ramirez, A., Jessen, F., Maier, W., Huell, M., Schroeder, J., Froelich, L., Teipel, S., Gruber, O., Kornhuber, J., Huston, J.P., Mueller, C.P. and Schaeble, S.
Proceedings of the National Academy of Sciences of the United States of America 110 (37): 15097-15102. 10 September 2013

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma.
Pfeifer, M., Grau, M., Lenze, D., Wenzel, S.S., Wolf, A., Wollert-Wulf, B. ORCID logoORCID: https://orcid.org/0009-0000-0257-4049, Dietze, K., Nogai, H., Storek, B., Madle, H., Dörken, B. ORCID logoORCID: https://orcid.org/0000-0001-7991-3643, Janz, M. ORCID logoORCID: https://orcid.org/0000-0002-1127-0044, Dirnhofer, S., Lenz, P., Hummel, M., Tzankov, A. and Lenz, G.
Proceedings of the National Academy of Sciences of the United States of America 110 (30): 12420-12425. 23 July 2013

Interfering with Gal-1-mediated angiogenesis contributes to the pathogenesis of preeclampsia.
Freitag, N. ORCID logoORCID: https://orcid.org/0000-0001-5972-1863, Tirado-González, I., Barrientos, G., Herse, F. ORCID logoORCID: https://orcid.org/0000-0002-9305-8134, Thijssen, V.L.J.L., Weedon-Fekjær, S.M., Schulz, H. ORCID logoORCID: https://orcid.org/0000-0002-0226-964X, Wallukat, G., Klapp, B.F., Nevers, T., Sharma, S., Staff, A.C., Dechend, R. ORCID logoORCID: https://orcid.org/0000-0001-6636-3080 and Blois, S.M. ORCID logoORCID: https://orcid.org/0000-0002-0434-2660
Proceedings of the National Academy of Sciences of the United States of America 110 (28): 11451-11456. 9 July 2013

Histone deacetylase 10 promotes autophagy-mediated cell survival.
Oehme, I., Linke, J.P., Böck, B.C., Milde, T., Lodrini, M., Hartenstein, B., Wiegand, I., Eckert, C., Roth, W., Kool, M., Kaden, S., Gröne, H.J., Schulte, J.H. ORCID logoORCID: https://orcid.org/0000-0003-0671-1201, Lindner, S., Hamacher-Brady, A., Brady, N.R., Deubzer, H.E. ORCID logoORCID: https://orcid.org/0000-0002-6115-4893 and Witt, O.
Proceedings of the National Academy of Sciences of the United States of America 110 (28): E2592-E2601. 9 July 2013

Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure.
Beetz, C., Johnson, A., Schuh, A.L., Thakur, S., Varga, R.E., Fothergill, T., Hertel, N., Bomba-Warczak, E., Thiele, H., Nürnberg, G., Altmüller, J. ORCID logoORCID: https://orcid.org/0000-0003-4372-1521, Saxena, R., Chapman, E.R., Dent, E.W., Nürnberg, P. and Audhya, A.
Proceedings of the National Academy of Sciences of the United States of America 110 (13): 5091-5096. 26 March 2013

Recruitment of oriens-lacunosum-moleculare interneurons during hippocampal ripples.
Pangalos, M., Donoso, J.R., Winterer, J., Zivkovic, A.R., Kempter, R., Maier, N. and Schmitz, D. ORCID logoORCID: https://orcid.org/0000-0003-2741-5241
Proceedings of the National Academy of Sciences of the United States of America 110 (11): 4398-4403. 12 March 2013

Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel.
Jin, L., Feng, T., Shih, H.P., Zerda, R., Luo, A., Hsu, J., Mahdavi, A., Sander, M. ORCID logoORCID: https://orcid.org/0000-0001-5308-7785, Tirrell, D.A., Riggs, A.D. and Ku, H.T.
Proceedings of the National Academy of Sciences of the United States of America 110 (10): 3907-12. 5 March 2013

Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides.
Wefers, B., Meyer, M., Ortiz, O., Hrabé de Angelis, M., Hansen, J., Wurst, W. and Kühn, R. ORCID logoORCID: https://orcid.org/0000-0003-1694-9803
Proceedings of the National Academy of Sciences of the United States of America 110 (10): 3782-3787. 5 March 2013

Compromised fidelity of endocytic synaptic vesicle protein sorting in the absence of stonin 2.
Kononenko, N.L., Diril, M.K., Puchkov, D., Kintscher, M., Koo, S.J., Pfuhl, G., Winter, Y., Wienisch, M., Klingauf, J., Breustedt, J., Schmitz, D. ORCID logoORCID: https://orcid.org/0000-0003-2741-5241, Maritzen, T. and Haucke, V.
Proceedings of the National Academy of Sciences of the United States of America 110 (6): E526-E535. 5 February 2013

Fas expression by tumor stroma is required for cancer eradication.
Listopad, J.J., Kammertoens, T. ORCID logoORCID: https://orcid.org/0000-0003-3309-5141, Anders, K. ORCID logoORCID: https://orcid.org/0000-0002-0429-200X, Silkenstedt, B., Willimsky, G. ORCID logoORCID: https://orcid.org/0000-0002-9693-948X, Schmidt, K. ORCID logoORCID: https://orcid.org/0000-0002-0572-6199, Kuehl, A.A., Loddenkemper, C. and Blankenstein, T. ORCID logoORCID: https://orcid.org/0000-0002-3357-4321
Proceedings of the National Academy of Sciences of the United States of America 110 (6): 2276-2281. 5 February 2013

Borna disease virus-induced neuronal degeneration dependent on host genetic background and prevented by soluble factors.
Wu, Y.J., Schulz, H. ORCID logoORCID: https://orcid.org/0000-0002-0226-964X, Lin, C.C., Saar, K. ORCID logoORCID: https://orcid.org/0000-0002-4483-1557, Patone, G. ORCID logoORCID: https://orcid.org/0000-0002-7242-0341, Fischer, H., Hübner, N. ORCID logoORCID: https://orcid.org/0000-0002-1218-6223, Heimrich, B. and Schwemmle, M.
Proceedings of the National Academy of Sciences of the United States of America 110 (5): 1899-1904. 29 January 2013

Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.
Echalier, A., Pan, Y., Birol, M. ORCID logoORCID: https://orcid.org/0000-0003-3397-8446, Tavernier, N., Pintard, L., Hoh, F., Ebel, C., Galophe, N., Claret, F.X. and Dumas, C.
Proceedings of the National Academy of Sciences of the United States of America 110 (4): 1273-1278. 22 January 2013

2012

Complexity of chromatin folding is captured by the strings and binders switch model.
Barbieri, M., Chotalia, M., Fraser, J., Lavitas, L.M., Dostie, J., Pombo, A. ORCID logoORCID: https://orcid.org/0000-0002-7493-6288 and Nicodemi, M.
Proceedings of the National Academy of Sciences of the United States of America 109 (40): 16173-16178. 2 October 2012

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells.
Vaeth, M., Schliesser, U., Mueller, G., Reissig, S., Satoh, K., Tuettenberg, A., Jonuleit, H., Waisman, A., Mueller, M.R., Serfling, E., Sawitzki, B.S. and Berberich-Siebelt, F.
Proceedings of the National Academy of Sciences of the United States of America 109 (40): 16258-16263. 2 October 2012

Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.
Greulich, H., Kaplan, B., Mertins, P. ORCID logoORCID: https://orcid.org/0000-0002-2245-528X, Chen, T.H., Tanaka, K.E., Yun, C.H., Zhang, X., Lee, S.H., Cho, J., Ambrogio, L., Liao, R., Imielinski, M., Banerji, S., Berger, A.H., Lawrence, M.S., Zhang, J., Pho, N.H., Walker, S.R., Winckler, W., Getz, G., Frank, D., Hahn, W.C., Eck, M.J., Mani, D.R., Jaffe, J.D., Carr, S.A., Wong, K.K. and Meyerson, M.
Proceedings of the National Academy of Sciences of the United States of America 109 (36): 14476-14481. 4 September 2012

Deletion of claudin-10 (Cldn10) in the thick ascending limb impairs paracellular sodium permeability and leads to hypermagnesemia and nephrocalcinosis.
Breiderhoff, T. ORCID logoORCID: https://orcid.org/0000-0002-1676-7498, Himmerkus, N., Stuiver, M., Mutig, K., Will, C., Meij, I.C. ORCID logoORCID: https://orcid.org/0000-0002-8189-2762, Bachmann, S., Bleich, M., Willnow, T.E. ORCID logoORCID: https://orcid.org/0000-0001-9515-7921 and Mueller, D.
Proceedings of the National Academy of Sciences of the United States of America 109 (35): 14241-14246. 28 August 2012

Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior.
Warner-Schmidt, J.L., Schmidt, E.F., Marshall, J.J., Rubin, A.J., Arango-Lievano, M., Kaplitt, M.G., Ibanez-Tallon, I., Heintz, N. and Greengard, P.
Proceedings of the National Academy of Sciences of the United States of America 109 (28): 11360-11365. 10 July 2012

Wnt/beta-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.
Klaus, A. ORCID logoORCID: https://orcid.org/0000-0002-1164-3322, Mueller, M., Schulz, H. ORCID logoORCID: https://orcid.org/0000-0002-0226-964X, Saga, Y., Martin, J.F. and Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 109 (27): 10921-10926. 3 July 2012

Modeling disease mutations by gene targeting in one-cell mouse embryos.
Meyer, M., Ortiz, O., Hrabe de Angelis, M., Wurst, W. and Kuehn, R. ORCID logoORCID: https://orcid.org/0000-0003-1694-9803
Proceedings of the National Academy of Sciences of the United States of America 109 (24): 9354-9359. 12 June 2012

Amorfrutins are potent antidiabetic dietary natural products.
Weidner, C., de Groot, J.C., Prasad, A., Freiwald, A., Quedenau, C. ORCID logoORCID: https://orcid.org/0000-0002-6846-4915, Kliem, M., Witzke, A., Kodelja, V., Han, C.T., Giegold, S., Baumann, M., Klebl, B., Siems, K., Müller-Kuhrt, L., Schürmann, A., Schüler, R., Pfeiffer, A.F.H., Schroeder, F.C., Büssow, K. and Sauer, S. ORCID logoORCID: https://orcid.org/0000-0002-4794-3693
Proceedings of the National Academy of Sciences of the United States of America 109 (19): 7257-7262. 8 May 2012

The protein expression landscape of the Arabidopsis root.
Petricka, J.J., Schauer, M.A., Megraw, M., Breakfield, N.W., Thompson, J.W., Georgiev, S., Soderblom, E.J., Ohler, U. ORCID logoORCID: https://orcid.org/0000-0002-0881-3116, Moseley, M.A., Grossniklaus, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 109 (18): 6811-6818. 1 May 2012

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages.
Schroder, K., Irvine, K.M., Taylor, M.S., Bokil, N.J., Le Cao, K.A., Masterman, K.A., Labzin, L.I., Semple, C.A., Kapetanovic, R., Fairbairn, L., Akalin, A. ORCID logoORCID: https://orcid.org/0000-0002-0468-0124, Faulkner, G.J., Baillie, J.K., Gongora, M., Daub, C.O., Kawaji, H., McLachlan, G.J., Goldman, N., Grimmond, S.M., Carninci, P., Suzuki, H., Hayashizaki, Y., Lenhard, B., Hume, D.A. and Sweet, M.J.
Proceedings of the National Academy of Sciences of the United States of America 109 (16): E944-E953. 17 April 2012

Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter.
Chua, J.J.E., Butkevich, E., Worseck, J.M., Kittelmann, M., Gronborg, M., Behrmann, E., Stelzl, U. ORCID logoORCID: https://orcid.org/0000-0003-2500-3585, Pavlos, N.J., Lalowski, M.M., Eimer, S., Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630, Klopfenstein, D.R. and Jahn, R.
Proceedings of the National Academy of Sciences of the United States of America 109 (15): 5862-5867. 10 April 2012

Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB.
Voutilainen, M., Lindfors, P.H., Lefebvre, S., Ahtiainen, L., Fliniaux, I., Rysti, E., Murtoniemi, M., Schneider, P., Schmidt-Ullrich, R. ORCID logoORCID: https://orcid.org/0000-0002-2472-6530 and Mikkola, M.L.
Proceedings of the National Academy of Sciences of the United States of America 109 (15): 5744-5749. 10 April 2012

2011

Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways.
D'Autreaux, F., Coppola, E., Hirsch, M.R., Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872 and Brunet, J.F.
Proceedings of the National Academy of Sciences of the United States of America 108 (50): 20018-20023. 13 December 2011

Interaction of complexes I, III, and IV within the bovine respirasome by single particle cryoelectron tomography.
Dudkina, N.V., Kudryashev, M. ORCID logoORCID: https://orcid.org/0000-0003-3550-6274, Stahlberg, H. and Boekema, E.J.
Proceedings of the National Academy of Sciences of the United States of America 108 (37): 15196-15200. 13 September 2011

Cellular correlate of assembly formation in oscillating hippocampal networks in vitro.
Baehner, F., Weiss, E.K., Birke, G., Maier, N., Schmitz, D. ORCID logoORCID: https://orcid.org/0000-0003-2741-5241, Rudolph, U., Frotscher, M., Traub, R.D., Both, M. and Draguhn, A.
Proceedings of the National Academy of Sciences of the United States of America 108 (35): E607-E616. 30 August 2011

Malt1-dependent RelB cleavage promotes canonical NF-κB activation in lymphocytes and lymphoma cell lines.
Hailfinger, S., Nogai, H., Pelzer, C., Jaworski, M., Cabalzar, K., Charton, J.E., Guzzardi, M., Decaillet, C., Grau, M., Doerken, B. ORCID logoORCID: https://orcid.org/0000-0001-7991-3643, Lenz, P., Lenz, G. and Thome, M.
Proceedings of the National Academy of Sciences of the United States of America 108 (35): 14596-14601. 30 August 2011

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses.
Koo, S.J., Markovic, S., Puchkov, D., Mahrenholz, C.C., Beceren-Braun, F., Maritzen, T., Dernedde, J., Volkmer, R., Oschkinat, H. and Haucke, V.
Proceedings of the National Academy of Sciences of the United States of America 108 (33): 13540-13545. 16 August 2011

Cholinergic chemosensory cells in the trachea regulate breathing.
Krasteva, G., Canning, B.J., Hartmann, P., Veres, T.Z., Papadakis, T., Muehlfeld, C., Schliecker, K., Tallini, Y.N., Braun, A., Hackstein, H., Baal, N., Weihe, E., Schuetz, B., Kotlikoff, M., Ibanez-Tallon, I. and Kummer, W.
Proceedings of the National Academy of Sciences of the United States of America 108 (23): 9478-9483. 7 June 2011

Structural insights into membrane fusion at the endoplasmic reticulum.
Daumke, O. ORCID logoORCID: https://orcid.org/0000-0002-6190-1414 and Praefcke, G.J.
Proceedings of the National Academy of Sciences of the United States of America 108 (6): 2175-2176. 8 February 2011

Critical role of PI3K signaling for NF-κB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells.
Kloo, B., Nagel, D., Pfeifer, M., Grau, M., Duewel, M., Vincendeau, M., Doerken, B. ORCID logoORCID: https://orcid.org/0000-0001-7991-3643, Lenz, P., Lenz, G. and Krappmann, D.
Proceedings of the National Academy of Sciences of the United States of America 108 (1): 272-277. 4 January 2011

Derivation of Ca2+ signals from puff properties reveals that pathway function is robust against cell variability but sensitive for control.
Thurley, K. and Falcke, M. ORCID logoORCID: https://orcid.org/0000-0001-7137-1114
Proceedings of the National Academy of Sciences of the United States of America 108 (1): 427-432. 4 January 2011

2010

Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Guenther, S., Schlundt, A., Sticht, J., Roske, Y. ORCID logoORCID: https://orcid.org/0000-0001-6237-388X, Heinemann, U. ORCID logoORCID: https://orcid.org/0000-0002-8191-3850, Wiesmueller, K.H., Jung, G., Falk, K., Roetzschke, O. and Freund, C.
Proceedings of the National Academy of Sciences of the United States of America 107 (51): 22219-22224. 21 December 2010

Impacting our young.
Marder, E., Kettenmann, H. ORCID logoORCID: https://orcid.org/0000-0001-8208-0291 and Grillner, S.
Proceedings of the National Academy of Sciences of the United States of America 107 (50): 21233. 14 December 2010

Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2).
Schwefel, D. ORCID logoORCID: https://orcid.org/0000-0002-2945-0908, Froehlich, C. ORCID logoORCID: https://orcid.org/0000-0002-2930-4097, Eichhorst, J., Wiesner, B., Behlke, J., Aravind, L. and Daumke, O. ORCID logoORCID: https://orcid.org/0000-0002-6190-1414
Proceedings of the National Academy of Sciences of the United States of America 107 (47): 20299-20304. 23 November 2010

A synthetic-natural hybrid oscillator in human cells.
Toettcher, J.E., Mock, C., Batchelor, E., Loewer, A. and Lahav, G.
Proceedings of the National Academy of Sciences of the United States of America 107 (39): 17047-17052. 28 September 2010

Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers.
Zhang, G., Hoersch, S., Amsterdam, A., Whittaker, C.A., Lees, J.A. and Hopkins, N.
Proceedings of the National Academy of Sciences of the United States of America 107 (39): 16940-16945. 28 September 2010

Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases.
Meyer, M., de Angelis, M.H., Wurst, W. and Kühn, R. ORCID logoORCID: https://orcid.org/0000-0003-1694-9803
Proceedings of the National Academy of Sciences of the United States of America 107 (34): 15022-15026. 24 August 2010

The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus.
Tzingounis, A.V., Heidenreich, M., Kharkovets, T., Spitzmaul, G., Jensen, H.S., Nicoll, R.A. and Jentsch, T.J. ORCID logoORCID: https://orcid.org/0000-0002-3509-2553
Proceedings of the National Academy of Sciences of the United States of America 107 (22): 10232-10237. 1 June 2010

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity.
Bieschke, J. ORCID logoORCID: https://orcid.org/0000-0002-3485-9767, Russ, J. ORCID logoORCID: https://orcid.org/0000-0001-6550-761X, Friedrich, R.P., Ehrnhoefer, D.E., Wobst, H., Neugebauer, K. and Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630
Proceedings of the National Academy of Sciences of the United States of America 107 (17): 7710-7715. 27 April 2010

Evidence for a functional sidedness to the (α)(β)TCR.
Kuhns, M.S., Girvin, A.T., Klein, L.O., Chen, R., Jensen, K.D.C., Newell, E.W., Huppa, J.B. ORCID logoORCID: https://orcid.org/0000-0003-2634-8198, Lillemeier, B.F., Huse, M., Chien, Y.H., Garcia, K.C. and Davis, M.M.
Proceedings of the National Academy of Sciences of the United States of America 107 (11): 5094-9. 16 March 2010

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation.
Haurie, V., Durrieu-Gaillard, S., Dumay-Odelot, H., Da Silva, D., Rey, C., Prochazkova, M., Roeder, R.G., Besser, D. ORCID logoORCID: https://orcid.org/0000-0002-4958-9624 and Teichmann, M.
Proceedings of the National Academy of Sciences of the United States of America 107 (9): 4176-4181. 2 March 2010

Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion.
Zhang, J., Piontek, J., Wolburg, H., Piehl, C., Liss, M. ORCID logoORCID: https://orcid.org/0000-0002-0585-7850, Otten, C. ORCID logoORCID: https://orcid.org/0000-0002-8230-7350, Christ, A. ORCID logoORCID: https://orcid.org/0000-0002-2019-176X, Willnow, T.E. ORCID logoORCID: https://orcid.org/0000-0001-9515-7921, Blasig, I.E. and Abdelilah-Seyfried, S. ORCID logoORCID: https://orcid.org/0000-0003-3183-3841
Proceedings of the National Academy of Sciences of the United States of America 107 (4): 1425-1430. 26 January 2010

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo.
Mortensen, M., Ferguson, D.J.P., Edelmann, M., Kessler, B., Morten, K.J., Komatsu, M. and Simon, A.K. ORCID logoORCID: https://orcid.org/0000-0002-4077-7995
Proceedings of the National Academy of Sciences of the United States of America 107 (2): 832-7. 12 January 2010

NCLX is an essential component of mitochondrial Na+/Ca2+ exchange.
Palty, R., Silverman, W.F., Hershfinkel, M., Caporale, T., Sensi, S.L., Parnis, J., Nolte, C. ORCID logoORCID: https://orcid.org/0000-0001-5398-3440, Fishman, D., Shoshan-Barmatz, V., Herrmann, S., Khananshvili, D. and Sekler, I.
Proceedings of the National Academy of Sciences of the United States of America 107 (1): 436-441. 5 January 2010

2009

CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens.
Nitta, T., Nitta, S., Lei, Y., Lipp, M. ORCID logoORCID: https://orcid.org/0000-0002-0087-2672 and Takahama, Y.
Proceedings of the National Academy of Sciences of the United States of America 106 (40): 17129-17133. 6 October 2009

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S., Wende, H. ORCID logoORCID: https://orcid.org/0000-0002-9168-8095, Paul, F.E. ORCID logoORCID: https://orcid.org/0000-0001-5181-3122, Cheret, C. ORCID logoORCID: https://orcid.org/0000-0001-7382-0403, Garratt, A.N. ORCID logoORCID: https://orcid.org/0000-0001-9631-3041, Zurborg, S., Feinberg, K., Besser, D. ORCID logoORCID: https://orcid.org/0000-0002-4958-9624, Schulz, H. ORCID logoORCID: https://orcid.org/0000-0002-0226-964X, Peles, E., Selbach, M. ORCID logoORCID: https://orcid.org/0000-0003-2454-8751, Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829 and Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons.
Schmidt, H., Stonkute, A., Juettner, R. ORCID logoORCID: https://orcid.org/0000-0003-3565-0698, Koesling, D., Friebe, A. and Rathjen, F.G. ORCID logoORCID: https://orcid.org/0000-0001-5351-613X
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16847-16852. 29 September 2009

Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system.
Stegbauer, J., Lee, D.H., Seubert, S., Ellrichmann, G., Manzel, A., Kvakan, H., Mueller, D.N. ORCID logoORCID: https://orcid.org/0000-0003-3650-5644, Gaupp, S., Rump, L.C., Gold, R. and Linker, R.A.
Proceedings of the National Academy of Sciences of the United States of America 106 (35): 14942-14947. 1 September 2009

Single-molecule force spectroscopy distinguishes target binding modes of calmodulin.
Junker, J.P. ORCID logoORCID: https://orcid.org/0000-0002-2826-8290 and Rief, M.
Proceedings of the National Academy of Sciences of the United States of America 106 (34): 14361-14366. 25 August 2009

Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis.
Blume, M., Rodriguez-Contreras, D., Landfear, S., Fleige, T., Soldati-Favre, D., Lucius, R. and Gupta, N.
Proceedings of the National Academy of Sciences of the United States of America 106 (31): 12998-13003. 4 August 2009

Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion.
Markovic, D.S., Vinnakota, K., Chirasani, S., Synowitz, M., Raguet, H., Stock, K., Sliwa, M., Lehmann, S., Kaelin, R., van Rooijen, N., Holmbeck, K., Heppner, F.L., Kiwit, J., Matyash, V., Lehnardt, S., Kaminska, B., Glass, R. and Kettenmann, H. ORCID logoORCID: https://orcid.org/0000-0001-8208-0291
Proceedings of the National Academy of Sciences of the United States of America 106 (30): 12530-12535. 28 July 2009

High-resolution profiling and discovery of planarian small RNAs.
Friedlaender, M.R. ORCID logoORCID: https://orcid.org/0000-0001-6577-4363, Adamidi, C., Han, T., Lebedeva, S. ORCID logoORCID: https://orcid.org/0000-0003-0857-8256, Isenbarger, T.A., Hirst, M., Marra, M., Nusbaum, C., Lee, W.L., Jenkin, J.C., Alvarado, A.S., Kim, J.K. and Rajewsky, N. ORCID logoORCID: https://orcid.org/0000-0002-4785-4332
Proceedings of the National Academy of Sciences of the United States of America 106 (28): 11546-11551. 14 July 2009

Growth retardation and altered autonomic control in mice lacking brain serotonin.
Alenina, N. ORCID logoORCID: https://orcid.org/0000-0002-6071-5433, Kikic, D., Todiras, M. ORCID logoORCID: https://orcid.org/0000-0002-9373-4753, Mosienko, V. ORCID logoORCID: https://orcid.org/0000-0002-8562-532X, Qadri, F. ORCID logoORCID: https://orcid.org/0000-0002-8500-489X, Plehm, R., Boye, P., Vilianovitch, L., Sohr, R., Tenner, K., Hoertnagl, H. and Bader, M. ORCID logoORCID: https://orcid.org/0000-0003-4780-4164
Proceedings of the National Academy of Sciences of the United States of America 106 (25): 10332-10337. 23 June 2009

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function.
Wang, S., Jensen, J.N., Seymour, P.A., Hsu, W., Dor, Y., Sander, M. ORCID logoORCID: https://orcid.org/0000-0001-5308-7785, Magnuson, M.A., Serup, P. and Gu, G.
Proceedings of the National Academy of Sciences of the United States of America 106 (24): 9715-20. 16 June 2009

The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse.
Vasyutina, E., Martarelli, B., Brakebusch, C., Wende, H. ORCID logoORCID: https://orcid.org/0000-0002-9168-8095 and Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 106 (22): 8935-8940. 2 June 2009

Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma.
Mathas, S. ORCID logoORCID: https://orcid.org/0000-0001-9626-1413, Kreher, S., Meaburn, K.J., Joehrens, K., Lamprecht, B., Assaf, C., Sterry, W., Kadin, M.E., Daibata, M., Joos, S., Hummel, M., Stein, H., Janz, M. ORCID logoORCID: https://orcid.org/0000-0002-1127-0044, Anagnostopoulos, I., Schrock, E., Misteli, T. and Doerken, B. ORCID logoORCID: https://orcid.org/0000-0001-7991-3643
Proceedings of the National Academy of Sciences of the United States of America 106 (14): 5831-5836. 7 April 2009

miR-375 maintains normal pancreatic α- and β-cell mass.
Poy, M.N. ORCID logoORCID: https://orcid.org/0000-0002-4904-2426, Hausser, J., Trajkovski, M., Braun, M., Collins, S., Rorsman, P., Zavolan, M. and Stoffel, M.
Proceedings of the National Academy of Sciences of the United States of America 106 (14): 5813-5818. 7 April 2009

A role for LYNX2 in anxiety-related behavior.
Tekinay, A.B., Nong, Y., Miwa, J.M., Lieberam, I., Ibanez-Tallon, I., Greengard, P. and Heintz, N.
Proceedings of the National Academy of Sciences of the United States of America 106 (11): 4477-4482. 17 March 2009

Quantifying environmental adaptation of metabolic pathways in metagenomics.
Gianoulis, T.A., Raes, J., Patel, P.V., Bjornson, R., Korbel, J.O., Letunic, I., Yamada, T., Paccanaro, A., Jensen, L.J. ORCID logoORCID: https://orcid.org/0000-0001-7885-715X, Snyder, M., Bork, P. ORCID logoORCID: https://orcid.org/0000-0002-2627-833X and Gerstein, M.B.
Proceedings of the National Academy of Sciences of the United States of America 106 (5): 1374-1379. 3 February 2009

Distinct mechanisms act in concert to mediate cell cycle arrest.
Toettcher, J.E., Loewer, A., Ostheimer, G.J., Yaffe, M.B., Tidor, B. and Lahav, G.
Proceedings of the National Academy of Sciences of the United States of America 106 (3): 785-790. 20 January 2009

DGCR8-dependent microRNA biogenesis is essential for skin development.
Yi, R., Pasolli, H.A., Landthaler, M. ORCID logoORCID: https://orcid.org/0000-0002-1075-8734, Hafner, M., Ojo, T., Sheridan, R., Sander, C., O'Carroll, D., Stoffel, M., Tuschl, T. and Fuchs, E.
Proceedings of the National Academy of Sciences of the United States of America 106 (2): 498-502. 13 January 2009

2008

Identification of gene 3' ends by automated EST cluster analysis.
Muro, E.M., Herrington, R., Janmohamed, S., Frelin, C., Andrade-Navarro, M.A. ORCID logoORCID: https://orcid.org/0000-0001-6650-1711 and Iscove, N.N.
Proceedings of the National Academy of Sciences of the United States of America 105 (51): 20286-20290. 23 December 2008

β-catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation.
Zelarayan, L.C. ORCID logoORCID: https://orcid.org/0000-0002-9001-0346, Noack, C., Sekkali, B., Kmecova, J., Gehrke, C., Renger, A., Zafiriou, M.P., van der Nagel, R., Dietz, R., de Windt, L.J., Balligand, J.L. and Bergmann, M.W.
Proceedings of the National Academy of Sciences of the United States of America 105 (50): 19762-19767. 16 December 2008

ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear.
Anselmi, F., Hernandez, V.H., Crispino, G., Seydel, A., Ortolano, S., Roper, S.D., Kessaris, N., Richardson, W., Rickheit, G., Filippov, M.A., Monyer, H. and Mammano, F.
Proceedings of the National Academy of Sciences of the United States of America 105 (48): 18770-18775. 2 December 2008

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas.
Kruschinski, A., Moosmann, A., Poschke, I., Norell, H., Chmielewski, M., Seliger, B., Kiessling, R., Blankenstein, T., Abken, H. and Charo, J. ORCID logoORCID: https://orcid.org/0000-0002-5409-9160
Proceedings of the National Academy of Sciences of the United States of America 105 (45): 17481-17486. 11 November 2008

Evolution of the phospho-tyrosine signaling machinery in premetazoan lineages.
Pincus, D., Letunic, I., Bork, P. ORCID logoORCID: https://orcid.org/0000-0002-2627-833X and Lim, W.A.
Proceedings of the National Academy of Sciences of the United States of America 105 (28): 9680-9684. 15 July 2008

Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking.
Hellmuth, K., Grosskopf, S., Lum, C.T., Wuertele, M., Roeder, N., von Kries, J.P. ORCID logoORCID: https://orcid.org/0000-0003-4716-4988, Rosario, M., Rademann, J. ORCID logoORCID: https://orcid.org/0000-0001-6678-3165 and Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 105 (20): 7275-7280. 20 May 2008

Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis.
Martin, M., Potente, M. ORCID logoORCID: https://orcid.org/0000-0002-5689-0036, Janssens, V., Vertommen, D., Twizere, J.C., Rider, M.H., Goris, J., Dimmeler, S., Kettmann, R. and Dequiedt, F.
Proceedings of the National Academy of Sciences of the United States of America 105 (12): 4727-4732. 25 March 2008

Transposition of a reconstructed Harbinger element in human cells and functional homology with two transposon-derived cellular genes.
Sinzelle, L., Kapitonov, V.V., Grzela, D.P. ORCID logoORCID: https://orcid.org/0000-0002-0667-6488, Jursch, T., Jurka, J., Izsvak, Z. ORCID logoORCID: https://orcid.org/0000-0002-2053-2384 and Ivics, Z. ORCID logoORCID: https://orcid.org/0000-0002-7803-6658
Proceedings of the National Academy of Sciences of the United States of America 105 (12): 4715-4720. 25 March 2008

Temporal compression mediated by short-term synaptic plasticity.
Leibold, C., Gundlfinger, A., Schmidt, R., Thurley, K., Schmitz, D. ORCID logoORCID: https://orcid.org/0000-0003-2741-5241 and Kempter, R.
Proceedings of the National Academy of Sciences of the United States of America 105 (11): 4417-4422. 18 March 2008

Requirement of protein kinase D1 for pathological cardiac remodeling.
Fielitz, J. ORCID logoORCID: https://orcid.org/0000-0001-8522-1045, Kim, M.S., Shelton, J.M., Qi, X., Hill, J.A., Richardson, J.A., Bassel-Duby, R. and Olson, E.N.
Proceedings of the National Academy of Sciences of the United States of America 105 (8): 3059-3063. 26 February 2008

A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer.
Kieback, E. ORCID logoORCID: https://orcid.org/0000-0003-3831-2846, Charo, J. ORCID logoORCID: https://orcid.org/0000-0002-5409-9160, Sommermeyer, D., Blankenstein, T. ORCID logoORCID: https://orcid.org/0000-0002-3357-4321 and Uckert, W.
Proceedings of the National Academy of Sciences of the United States of America 105 (2): 623-628. 15 January 2008

2007

Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis.
Klaus, A. ORCID logoORCID: https://orcid.org/0000-0002-1164-3322, Saga, Y., Taketo, M.M., Tzahor, E. and Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 104 (47): 18531-18536. 20 November 2007

Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
Schaeper, U., Vogel, R., Chmielowiec, J., Huelsken, J., Rosario, M. and Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 104 (39): 15376-15381. 25 September 2007

Proteasomal selection of multiprotein complexes recruited by LIM homeodomain transcription factors.
Guengoer, C., Taniguchi-Ishigaki, N., Ma, H., Drung, A., Tursun, B. ORCID logoORCID: https://orcid.org/0000-0001-7293-8629, Ostendorff, H.P., Bossenz, M., Becker, C.G., Becker, T. and Bach, I.
Proceedings of the National Academy of Sciences of the United States of America 104 (38): 15000-15005. 18 September 2007

Quantitative assessment of protein function prediction from metagenomics shotgun sequences.
Harrington, E.D., Singh, A.H., Doerks, T., Letunic, I., von Mering, C. ORCID logoORCID: https://orcid.org/0000-0001-7734-9102, Jensen, L.J. ORCID logoORCID: https://orcid.org/0000-0001-7885-715X, Raes, J. and Bork, P. ORCID logoORCID: https://orcid.org/0000-0002-2627-833X
Proceedings of the National Academy of Sciences of the United States of America 104 (35): 13913-13918. 28 August 2007

TRPA1 mediates formalin-induced pain.
McNamara, C.R., Mandel-Brehm, J., Bautista, D.M., Siemens, J., Deranian, K.L., Zhao, M., Hayward, N.J., Chong, J.A., Julius, D., Moran, M.M. and Fanger, C.M.
Proceedings of the National Academy of Sciences of the United States of America 104 (33): 13525-13530. 14 August 2007

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Trevisani, M., Siemens, J., Materazzi, S., Bautista, D.M., Nassini, R., Campi, B., Imamachi, N., Andre, E., Patacchini, R., Cottrell, G.S., Gatti, R., Basbaum, A.I., Bunnett, N.W., Julius, D. and Geppetti, P.
Proceedings of the National Academy of Sciences of the United States of America 104 (33): 13519-13524. 14 August 2007

Cellular cofactors affecting hepatitis C virus infection and replication.
Randall, G., Panis, M., Cooper, J.D., Tellinghuisen, T.L., Sukhodolets, K.E., Pfeffer, S., Landthaler, M. ORCID logoORCID: https://orcid.org/0000-0002-1075-8734, Landgraf, P., Kan, S., Lindenbach, B.D., Chien, M., Weir, D.B., Russo, J.J., Ju, J., Brownstein, M.J., Sheridan, R., Sander, C., Zavolan, M., Tuschl, T. and Rice, C.M.
Proceedings of the National Academy of Sciences of the United States of America 104 (31): 12884-12889. 31 July 2007

Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance.
Piaggio, E., Mars, L.T., Cassan, C., Cabarrocas, J., Hofstätter, M. ORCID logoORCID: https://orcid.org/0000-0002-6198-2859, Desbois, S., Bergereau, E., Roetzschke, O., Falk, K. and Liblau, R.S.
Proceedings of the National Academy of Sciences of the United States of America 104 (22): 9393-9398. 29 May 2007

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.
Nielsen, R., Courtoy, P.J., Jacobsen, C., Dom, G., Lima, W.R., Jadot, M., Willnow, T.E. ORCID logoORCID: https://orcid.org/0000-0001-9515-7921, Devuyst, O. and Christensen, E.I.
Proceedings of the National Academy of Sciences of the United States of America 104 (13): 5407-5412. 27 March 2007

Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction.
Fielitz, J. ORCID logoORCID: https://orcid.org/0000-0001-8522-1045, van Rooij, E., Spencer, J.A., Shelton, J.M., Latif, S., van der Nagel, R., Bezprozvannaya, S., de Windt, L., Richardson, J.A., Bassel-Duby, R. and Olson, E.N.
Proceedings of the National Academy of Sciences of the United States of America 104 (11): 4377-4382. 13 March 2007

RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells.
Vasyutina, E., Lenhard, D.C., Wende, H. ORCID logoORCID: https://orcid.org/0000-0002-9168-8095, Erdmann, B., Epstein, J.A. and Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 104 (11): 4443-4448. 13 March 2007

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy.
Radke, M.H. ORCID logoORCID: https://orcid.org/0000-0003-0112-9917, Peng, J., Wu, Y., McNabb, M., Nelson, O.L., Granzier, H. ORCID logoORCID: https://orcid.org/0000-0002-9516-407X and Gotthardt, M. ORCID logoORCID: https://orcid.org/0000-0003-1788-3172
Proceedings of the National Academy of Sciences of the United States of America 104 (9): 3444-3449. 27 February 2007

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.
Suchting, S., Freitas, C., le Noble, F. ORCID logoORCID: https://orcid.org/0000-0001-6195-7672, Benedito, R., Breant, C., Duarte, A. and Eichmann, A.
Proceedings of the National Academy of Sciences of the United States of America 104 (9): 3225-3230. 27 February 2007

SOX9 is required for maintenance of the pancreatic progenitor cell pool.
Seymour, P.A., Freude, K.K., Tran, M.N., Mayes, E.E., Jensen, J., Kist, R., Scherer, G. and Sander, M. ORCID logoORCID: https://orcid.org/0000-0001-5308-7785
Proceedings of the National Academy of Sciences of the United States of America 104 (6): 1865-70. 6 February 2007

2006

Continuous tooth generation in mouse is induced by activated epithelial Wnt/β-catenin signaling.
Jaervinen, E., Salazar-Ciudad, I., Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829, Taketo, M.M., Jernvall, J. and Thesleff, I.
Proceedings of the National Academy of Sciences of the United States of America 103 (49): 18627-18632. 5 December 2006

Murine inner cell mass-derived lineages depend on Sall4 function.
Elling, U., Klasen, C., Eisenberger, T., Anlag, K. and Treier, M. ORCID logoORCID: https://orcid.org/0000-0002-8751-1246
Proceedings of the National Academy of Sciences of the United States of America 103 (44): 16319-16324. 31 October 2006

Diversin regulates heart formation and gastrulation movements in development.
Moeller, H., Jenny, A., Schaeffer, H.J. ORCID logoORCID: https://orcid.org/0000-0003-2010-9153, Schwarz-Romond, T., Mlodzik, M., Hammerschmidt, M. and Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 103 (43): 15900-15905. 24 October 2006

Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis.
Sakai, N., Wada, T., Yokoyama, H., Lipp, M. ORCID logoORCID: https://orcid.org/0000-0002-0087-2672, Ueha, S., Matsushima, K. and Kaneko, S.
Proceedings of the National Academy of Sciences of the United States of America 103 (38): 14098-14103. 19 September 2006

Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6.
Poet, M., Kornak, U., Schweizer, M., Zdebik, A.A., Scheel, O., Hoelter, S., Wurst, W., Schmitt, A., Fuhrmann, J.C. ORCID logoORCID: https://orcid.org/0000-0001-5730-381X, Planells-Cases, R., Mole, S.E., Huebner, C.A. and Jentsch, T.J. ORCID logoORCID: https://orcid.org/0000-0002-3509-2553
Proceedings of the National Academy of Sciences of the United States of America 103 (37): 13854-13859. 12 September 2006

Unique self-palmitoylation activity of the transport protein particle component Bet3: A mechanism required for protein stability.
Kuemmel, D. ORCID logoORCID: https://orcid.org/0000-0003-3950-5914, Heinemann, U. ORCID logoORCID: https://orcid.org/0000-0002-8191-3850 and Veit, M.
Proceedings of the National Academy of Sciences of the United States of America 103 (34): 12701-12706. 22 August 2006

Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer.
Hadjihannas, M.V., Brueckner, M., Jerchow, B., Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829, Dietmaier, W. and Behrens, J.
Proceedings of the National Academy of Sciences of the United States of America 103 (28): 10747-10752. 11 July 2006

Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destruction.
Geibel, J., Sritharan, K., Geibel, R., Geibel, P., Persing, J.S., Seeger, A., Roepke, T.K., Deichstetter, M., Prinz, C., Cheng, S.X., Martin, D. and Hebert, S.C.
Proceedings of the National Academy of Sciences of the United States of America 103 (25): 9390-9397. 20 June 2006

Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.
Wagner, K., Zhang, P., Rosenbauer, F. ORCID logoORCID: https://orcid.org/0000-0001-7977-9421, Drescher, B., Kobayashi, S., Radomska, H.S., Kutok, J.L., Gilliland, D.G., Krauter, J. and Tenen, D.G.
Proceedings of the National Academy of Sciences of the United States of America 103 (16): 6338-6343. 18 April 2006

Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots.
Lee, J.Y., Colinas, J., Wang, J.Y., Mace, D., Ohler, U. ORCID logoORCID: https://orcid.org/0000-0002-0881-3116 and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 103 (15): 6055-6060. 11 April 2006

A structural role for ATP in the formation and stability of the human origin recognition complex.
Ranjan, A. and Gossen, M. ORCID logoORCID: https://orcid.org/0000-0002-1761-4063
Proceedings of the National Academy of Sciences of the United States of America 103 (13): 4864-4869. 28 March 2006

Cardiac hypertrophy in transgenic rats expressing a dominant-negative mutant of the natriuretic peptide receptor B.
Langenickel, T.H., Buttgereit, J., Pagel-Langenickel, I., Lindner, M., Monti, J., Beuerlein, K., Al-Saadi, N., Plehm, R., Popova, E. ORCID logoORCID: https://orcid.org/0000-0002-3043-9650, Tank, J., Dietz, R., Willenbrock, R. and Bader, M. ORCID logoORCID: https://orcid.org/0000-0003-4780-4164
Proceedings of the National Academy of Sciences of the United States of America 103 (12): 4735-4740. 21 March 2006

Sleeping Beauty transposase modulates cell-cycle progression through interaction with Miz-1.
Walisko, O., Izsvak, Z. ORCID logoORCID: https://orcid.org/0000-0002-2053-2384, Szabo, K., Kaufman, C.D. ORCID logoORCID: https://orcid.org/0009-0001-9888-7740, Herold, S. and Ivics, Z. ORCID logoORCID: https://orcid.org/0000-0002-7803-6658
Proceedings of the National Academy of Sciences of the United States of America 103 (11): 4062-4067. 14 March 2006

Running in pregnancy transiently increases postnatal hippocampal neurogenesis in the offspring.
Bick-Sander, A., Steiner, B., Wolf, S.A. ORCID logoORCID: https://orcid.org/0000-0003-0922-8418, Babu, H. and Kempermann, G. ORCID logoORCID: https://orcid.org/0000-0002-5304-4061
Proceedings of the National Academy of Sciences of the United States of America 103 (10): 3852-3857. 7 March 2006

Cell type specific signatures of microRNAs on target mRNA expression.
Sood, P., Krek, A., Zavolan, M., Macino, G. and Rajewsky, N. ORCID logoORCID: https://orcid.org/0000-0002-4785-4332
Proceedings of the National Academy of Sciences of the United States of America 103 (8): 2746-2751. 21 February 2006

13C isotopologue perturbation studies of Listeria monocytogenes carbon metabolism and its modulation by the virulence regulator PrfA.
Eisenreich, W., Slaghuis, J., Laupitz, R., Bussemer, J., Stritzker, J., Schwarz, C., Schwarz, R. ORCID logoORCID: https://orcid.org/0000-0001-9155-4268, Dandekar, T., Goebel, W. and Bacher, A.
Proceedings of the National Academy of Sciences of the United States of America 103 (7): 2040-2045. 14 February 2006

Natural variation and genetic covariance in adult hippocampal neurogenesis.
Kempermann, G. ORCID logoORCID: https://orcid.org/0000-0002-5304-4061, Chesler, E.J., Lu, L., Williams, R.W. and Gage, F.H.
Proceedings of the National Academy of Sciences of the United States of America 103 (3): 780-785. 17 January 2006

2005

Spatial regulation of microRNA gene expression in the Drosophila embryo.
Biemar, F., Zinzen, R.P. ORCID logoORCID: https://orcid.org/0000-0002-8638-5102, Ronshaugen, M., Sementchenko, V., Manak, J.R. and Levine, M.S.
Proceedings of the National Academy of Sciences of the United States of America 102 (44): 15907-15911. 1 November 2005

Auditory orientation in crickets: pattern recognition controls reactive steering.
Poulet, J.F.A. ORCID logoORCID: https://orcid.org/0000-0003-0296-5415 and Hedwig, B.
Proceedings of the National Academy of Sciences of the United States of America 102 (43): 15665-15669. 25 October 2005

Viral targeting of the interferon-beta-inducing Traf family member-associated NF-kappaB activator (TANK)-binding kinase-1.
Unterstab, G., Ludwig, S., Anton, A., Planz, O., Dauber, B., Krappmann, D. ORCID logoORCID: https://orcid.org/0000-0001-7640-3234, Heins, G., Ehrhardt, C. and Wolff, T.
Proceedings of the National Academy of Sciences of the United States of America 102 (38): 13640-13645. 9 September 2005

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Andersen, O.M. ORCID logoORCID: https://orcid.org/0000-0003-4226-3354, Reiche, J., Schmidt, V. ORCID logoORCID: https://orcid.org/0000-0002-5851-1087, Gotthardt, M. ORCID logoORCID: https://orcid.org/0000-0003-1788-3172, Spoelgen, R., Behlke, J., von Arnim, C.A.F., Breiderhoff, T. ORCID logoORCID: https://orcid.org/0000-0002-1676-7498, Jansen, P., Wu, X., Bales, K.R., Cappai, R., Masters, C.L., Gliemann, J., Mufson, E.J., Hyman, B.T., Paul, S.M., Nykjaer, A. and Willnow, T.E. ORCID logoORCID: https://orcid.org/0000-0001-9515-7921
Proceedings of the National Academy of Sciences of the United States of America 102 (38): 13461-13466. 7 September 2005

The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex.
Otto, H., Conz, C., Maier, P., Woelfle, T., Suzuki, C.K., Jenoe, P., Ruecknagel, P., Stahl, J. and Rospert, S.
Proceedings of the National Academy of Sciences of the United States of America 102 (29): 10064-10069. 19 July 2005

Recruitment of DNA methyltransferase I to DNA repair sites.
Mortusewicz, O., Schermelleh, L., Walter, J., Cardoso, M.C. ORCID logoORCID: https://orcid.org/0000-0001-8427-8859 and Leonhardt, H. ORCID logoORCID: https://orcid.org/0000-0002-5086-6449
Proceedings of the National Academy of Sciences of the United States of America 102 (25): 8905-8909. 21 June 2005

A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse.
Zheng, Z., Schmidt-Ott, K.M., Chua, S., Foster, K.A., Frankel, R.Z., Pavlidis, P., Barasch, J., D'Agati, V.D. and Gharavi, A.G.
Proceedings of the National Academy of Sciences of the United States of America 102 (7): 2502-2507. 15 February 2005

A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo.
Zhang, X., Smith, D.L., Meriin, A.B., Engemann, S., Russel, D.E., Roark, M., Washington, S.L., Maxwell, M.M., Marsh, J.L., Thompson, L.M., Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630, Young, A.B., Housman, D.E., Bates, G.P., Sherman, M.Y. and Kazantsev, A.G.
Proceedings of the National Academy of Sciences of the United States of America 102 (3): 892-897. 18 January 2005

2004

Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele.
Graveel, C., Su, Y., Koeman, J., Wang, L.M., Tessarollo, L., Fiscella, M., Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872, Swiatek, P., Bronson, R. and Vande Woude, G.F.
Proceedings of the National Academy of Sciences of the United States of America 101 (49): 17198-17203. 7 December 2004

Loss of chondroitin 6-O-sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement.
Thiele, H., Sakano, M., Kitagawa, H., Sugahara, K., Rajab, A., Hoehne, W., Ritter, H., Leschik, G., Nuernberg, P. and Mundlos, S.
Proceedings of the National Academy of Sciences of the United States of America 101 (27): 10155-10160. 23 June 2004

A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway.
Bush, E., Fielitz, J. ORCID logoORCID: https://orcid.org/0000-0001-8522-1045, Melvin, L., Martinez-Arnold, M., McKinsey, T.A., Plichta, R. and Olson, E.N.
Proceedings of the National Academy of Sciences of the United States of America 101 (9): 2870-2875. 2 March 2004

The MafA transcription factor appears to be responsible for tissue-specific expression of insulin.
Matsuoka, T., Artner, I., Henderson, E., Means, A., Sander, M. ORCID logoORCID: https://orcid.org/0000-0001-5308-7785 and Stein, R.
Proceedings of the National Academy of Sciences of the United States of America 101 (9): 2930-3. 2 March 2004

Met provides essential signals for liver regeneration.
Borowiak, M. ORCID logoORCID: https://orcid.org/0000-0002-5829-1213, Garratt, A.N. ORCID logoORCID: https://orcid.org/0000-0001-9631-3041, Wuestefeld, T., Strehle, M., Trautwein, C. and Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 101 (29): 10608-10613. 1 January 2004

2003

Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses.
Moore, K.A., Nicoll, R.A. and Schmitz, D. ORCID logoORCID: https://orcid.org/0000-0003-2741-5241
Proceedings of the National Academy of Sciences of the United States of America 100 (24): 14397-14402. 25 November 2003

α1E-containing Ca2+ channels are involved in synaptic plasticity.
Breustedt, J., Vogt, K.E., Miller, R.J., Nicoll, R.A. and Schmitz, D. ORCID logoORCID: https://orcid.org/0000-0003-2741-5241
Proceedings of the National Academy of Sciences of the United States of America 100 (21): 12450-12455. 14 October 2003

Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2.
Lehmann, K., Seemann, P., Stricker, S., Sammar, M., Meyer, B., Suering, K., Majewski, F., Tinschert, S., Grzeschik, K.H., Mueller, D., Knaus, P., Nuernberg, P. and Mundlos, S.
Proceedings of the National Academy of Sciences of the United States of America 100 (21): 12277-12282. 14 October 2003

Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.
Wolfrum, C., Besser, D., Luca, E. and Stoffel, M.
Proceedings of the National Academy of Sciences of the United States of America 100 (20): 11624-11629. 30 September 2003

Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas.
Santos, R.A.S. ORCID logoORCID: https://orcid.org/0000-0001-8738-5852, e Silva, A.C.S., Maric, C., Silva, D.M.R., Machado, R.P., de Buhr, I., Heringer-Walther, S., Pinheiro, S.V.B., Lopes, M.T., Bader, M. ORCID logoORCID: https://orcid.org/0000-0003-4780-4164, Mendes, E.P., Lemos, V.S., Campagnole-Santos, M.J. ORCID logoORCID: https://orcid.org/0000-0001-9483-4206, Schultheiss, H.P., Speth, R. and Walther, T.
Proceedings of the National Academy of Sciences of the United States of America 100 (14): 8258-8263. 8 July 2003

Polyglutamine fibrillogenesis: The pathway unfolds.
Ross, C.A., Poirier, M.A., Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630 and Amzel, M.
Proceedings of the National Academy of Sciences of the United States of America 100 (1): 1-3. 7 January 2003

Preferential megalin-mediated transcytosis of low-hormonogenic thyroglobulin: A control mechanism for thyroid hormone release.
Lisi, S., Pinchera, A., McCluskey, R.T., Willnow, T.E. ORCID logoORCID: https://orcid.org/0000-0001-9515-7921, Refetoff, S., Marcocci, C., Vitti, P., Menconi, F., Grasso, L., Luchetti, F., Collins, A.B. and Marino, M.
Proceedings of the National Academy of Sciences of the United States of America 100 (25): 14858-14863. 1 January 2003

Genome evolution reveals biochemical networks and functional modules.
von Mering, C. ORCID logoORCID: https://orcid.org/0000-0001-7734-9102, Zdobnov, E.M., Tsoka, S., Ciccarelli, F.D., Pereira-Leal, J.B., Ouzounis, C.A. and Bork, P. ORCID logoORCID: https://orcid.org/0000-0002-2627-833X
Proceedings of the National Academy of Sciences of the United States of America 100 (26): 15428-15433. 1 January 2003

2002

A pH-sensitive histidine residue as control element for ligand release from HLA-DR molecules.
Roetzschke, O., Lau, J.M., Hofstätter, M. ORCID logoORCID: https://orcid.org/0000-0002-6198-2859, Falk, K. and Strominger, J.L.
Proceedings of the National Academy of Sciences of the United States of America 99 (26): 16946-16950. 24 December 2002

Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay.
Heiser, V., Engemann, S., Broecker, W., Dunkel, I., Boeddrich, A. ORCID logoORCID: https://orcid.org/0000-0001-9118-050X, Waelter, S., Nordhoff, E., Lurz, R., Schugardt, N., Rautenberg, S., Herhaus, C., Barnickel, G., Boettcher, H., Lehrach, H. and Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630
Proceedings of the National Academy of Sciences of the United States of America 99 (Suppl 4): 16400-16406. 10 December 2002

The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions.
Siemens, J., Kazmierczak, P., Reynolds, A., Sticker, M., Littlewood-Evans, A. and Mueller, U.
Proceedings of the National Academy of Sciences of the United States of America 99 (23): 14946-14951. 12 November 2002

Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy.
Knauf, F., Rogina, B., Jiang, Z., Aronson, P.S. and Helfand, S.L.
Proceedings of the National Academy of Sciences of the United States of America 99 : 14315-14319. 29 October 2002

The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract.
Schell, M.A., Karmirantzou, M., Snel, B., Vilanova, D., Berger, B., Pessi, G., Zwahlen, M.C., Desiere, F., Bork, P., Delley, M., Pridmore, R.D. and Arigoni, F.
Proceedings of the National Academy of Sciences of the United States of America 99 (22): 14422-14427. 29 October 2002

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Özcelik, C., Erdmann, B., Pilz, B., Wettschureck, N., Britsch, S. ORCID logoORCID: https://orcid.org/0000-0003-4379-3322, Hübner, N. ORCID logoORCID: https://orcid.org/0000-0002-1218-6223, Chien, K.R., Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872 and Garratt, A.N. ORCID logoORCID: https://orcid.org/0000-0001-9631-3041
Proceedings of the National Academy of Sciences of the United States of America 99 (13): 8880-8885. 25 June 2002

Comparative genomic analysis in the region of a major Plasmodium-refractoriness locus of Anopheles gambiae.
Thomasova, D., Ton, L.Q., Copley, R.R., Zdobnov, E.M., Wang, X., Hong, Y.S., Sim, C., Bork, P., Kafatos, F.C. and Collins, F.H.
Proceedings of the National Academy of Sciences of the United States of America 99 : 8179-8184. 11 June 2002

Probabilistic clustering of sequences: inferring new bacterial regulons by comparative genomics.
van Nimwegen, E., Zavolan, M., Rajewsky, N. ORCID logoORCID: https://orcid.org/0000-0002-4785-4332 and Siggia, E.D.
Proceedings of the National Academy of Sciences of the United States of America 99 (11): 7323-7328. 28 May 2002

Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure.
Holtwick, R., Gotthardt, M. ORCID logoORCID: https://orcid.org/0000-0003-1788-3172, Skryabin, B., Steinmetz, M., Potthast, R., Zetsche, B., Hammer, R.E., Herz, J. and Kuhn, M.
Proceedings of the National Academy of Sciences of the United States of America 99 : 7142-7147. 14 May 2002

The identification of functional modules from the genomic association of genes.
Snel, B., Bork, P. and Huynen, M.A.
Proceedings of the National Academy of Sciences of the United States of America 99 : 5890-5895. 30 April 2002

Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid β-peptide of amyloid plaques.
Perutz, M.F., Pope, B.J., Owen, D., Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630 and Scherzinger, E.
Proceedings of the National Academy of Sciences of the United States of America 99 (8): 5596-5600. 16 April 2002

Evidence for a NOD2-independent susceptibility locus for inflammatory bowel disease on chromosome 16p.
Hampe, J., Frenzel, H., Mirza, M.M., Croucher, P.J., Cuthbert, A., Mascheretti, S., Huse, K., Platzer, M., Bridger, S., Meyer, B., Nuernberg, P., Stokkers, P., Krawczak, M., Mathew, C.G., Curran, M. and Schreiber, S.
Proceedings of the National Academy of Sciences of the United States of America 99 (1): 321-326. 8 January 2002

2001

Bazooka and atypical protein kinase C are required to regulate oocyte differentiation in the Drosophila ovary.
Cox, D.N., Seyfried, S.A. ORCID logoORCID: https://orcid.org/0000-0003-3183-3841, Jan, L.Y. and Jan, Y.N.
Proceedings of the National Academy of Sciences of the United States of America 98 : 14475-14480. 4 December 2001

Vaccination, prevention, and treatment of experimental autoimmune neuritis (EAN) by an oligomerized T cell epitope.
Stienekemeier, M., Falk, K., Roetzschke, O., Weishaupt, A., Schneider, C., Toyka, K.V., Gold, R. and Strominger, J.L.
Proceedings of the National Academy of Sciences of the United States of America 98 (24): 13872-13877. 1 November 2001

Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channel.
Dedek, K., Kunath, B., Kananura, C., Reuner, U., Jentsch, T.J. ORCID logoORCID: https://orcid.org/0000-0002-3509-2553 and Steinlein, O.K.
Proceedings of the National Academy of Sciences of the United States of America 98 (21): 12272-12277. 9 October 2001

Presynaptic kainate receptors at hippocampal mossy fiber synapses.
Schmitz, D. ORCID logoORCID: https://orcid.org/0000-0003-2741-5241, Mellor, J., Frerking, M. and Nicoll, R.A.
Proceedings of the National Academy of Sciences of the United States of America 98 (20): 11003-11008. 25 September 2001

When genetic distance matters: measuring genetic differentiation at microsatellite loci in whole-genome scans of recent and incipient mosquito species.
Wang, R., Zheng, L., Toure, Y.T., Dandekar, T. and Kafatos, F.C.
Proceedings of the National Academy of Sciences of the United States of America 98 (19): 10769-10774. 11 September 2001

The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia.
Fuchs, U., Rehkamp, G., Haas, O.A., Slany, R., Konig, M., Bojesen, S., Bohle, R.M., Damm-Welk, C., Ludwig, W.D., Harbott, J. and Borkhardt, A.
Proceedings of the National Academy of Sciences of the United States of America 98 (15): 8756-8761. 17 July 2001

BDNF but not NT-4 is required for normal flexion reflex plasticity and function.
Heppenstall, P.A. and Lewin, G.R. ORCID logoORCID: https://orcid.org/0000-0002-2890-6352
Proceedings of the National Academy of Sciences of the United States of America 98 (14): 8107-8112. 3 July 2001

Tumor necrosis factor-related apoptosis-inducing ligand in T cell development: sensitivity of human thymocytes.
Simon, A.K. ORCID logoORCID: https://orcid.org/0000-0002-4077-7995, Williams, O., Mongkolsapaya, J., Jin, B., Xu, X.N., Walczak, H. and Screaton, G.R.
Proceedings of the National Academy of Sciences of the United States of America 98 (9): 5158-63. 24 April 2001

Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia.
Kozyraki, R., Fyfe, J., Verroust, P.J., Jacobsen, C., Dautry-Varsat, A., Gburek, J., Willnow, T.E. ORCID logoORCID: https://orcid.org/0000-0001-9515-7921, Christensen, E.I. and Moestrup, S.K.
Proceedings of the National Academy of Sciences of the United States of America 98 (22): 12491-12496. 1 January 2001

S100A1: A regulator of myocardial contractility.
Most, P., Bernotat, J., Ehlermann, P., Pleger, S.T., Reppel, M., Boerries, M., Niroomand, F., Pieske, B., Janssen, P.M.L., Eschenhagen, T., Karczewski, P., Smith, G.L., Koch, W.J.K., Katus, H.A. and Remppis, A.
Proceedings of the National Academy of Sciences of the United States of America 98 (24): 13889-13894. 1 January 2001

Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D-3.
Nykjaer, A., Fyfe, J.C., Kozyraki, R., Leheste, J.R., Jacobsen, C., Nielsen, M.S., Verroust, P.J., Aminoff, M., de la Chapelle, A., Moestrup, S.K., Ray, R., Gliemann, J., Willnow, T.E. ORCID logoORCID: https://orcid.org/0000-0001-9515-7921 and Christensen, E.I.
Proceedings of the National Academy of Sciences of the United States of America 98 (24): 13895-13900. 1 January 2001

Paternal relatedness and age proximity regulate social relationships among adult female rhesus macaques.
Widdig, A., Nuernberg, P., Krawczak, M., Streich, W.J. and Bercovitch, F.B.
Proceedings of the National Academy of Sciences of the United States of America 98 (24): 13769-13773. 1 January 2001

2000

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils.
Muchowski, P.J., Schaffar, G., Sittler, A., Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630, Hayer-Hartl, M.K. and Hartl, F.U.
Proceedings of the National Academy of Sciences of the United States of America 97 (14): 7841-7846. 5 July 2000

Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.
Nylandsted, J., Rohde, M., Brand, K., Bastholm, L., Elling, F. and Jaattela, M.
Proceedings of the National Academy of Sciences of the United States of America 97 (14): 7871-7876. 5 July 2000

Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors.
Pesquero, J.B., Araujo, R.C. ORCID logoORCID: https://orcid.org/0000-0003-0095-4608, Heppenstall, P.A., Stucky, C.L., Silva, J.A., Walther, T., Oliveira, S.M., Pesquero, J.L., Paiva, A.C.M., Calixto, J.B., Lewin, G.R. ORCID logoORCID: https://orcid.org/0000-0002-2890-6352 and Bader, M. ORCID logoORCID: https://orcid.org/0000-0003-4780-4164
Proceedings of the National Academy of Sciences of the United States of America 97 (14): 8140-8145. 5 July 2000

Anopheles gambiae pilot gene discovery project: Identification of mosquito innate immunity genes from expressed sequence tags generated from immune-competent cell lines.
Dimopoulos, G., Casavant, T.L., Chang, S.R., Scheetz, T., Roberts, C., Donohue, M., Schultz, J., Benes, V., Bork, P., Ansorge, W., Soares, M.B. and Kafatos, F.C.
Proceedings of the National Academy of Sciences of the United States of America 97 (12): 6619-6624. 6 June 2000

Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy.
Heiser, V., Scherzinger, E., Boeddrich, A., Nordhoff, E., Lurz, R., Schugardt, N., Lehrach, H. and Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630
Proceedings of the National Academy of Sciences of the United States of America 97 (12): 6739-6744. 6 June 2000

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
Steffan, J.S., Kazantsev, A., Spasic-Boskovic, O., Greenwald, M., Zhu, Y.Z., Gohler, H., Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630, Bates, G.P., Housman, D.E. and Thompson, L.M.
Proceedings of the National Academy of Sciences of the United States of America 97 : 6763-6768. 6 June 2000

KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway.
Kharkovets, T., Hardelin, J.P., Safieddine, S., Schweizer, M., El-Amraoui, A., Petit, C. and Jentsch, T.J. ORCID logoORCID: https://orcid.org/0000-0002-3509-2553
Proceedings of the National Academy of Sciences of the United States of America 97 (8): 4333-4338. 11 April 2000

1999

Pax6 is essential for establishing ventral-dorsal cell boundaries in pituitary gland development.
Kioussi, C., O'Connell, S., St-Onge, L., Treier, M. ORCID logoORCID: https://orcid.org/0000-0002-8751-1246, Gleiberman, A.S., Gruss, P. and Rosenfeld, M.G.
Proceedings of the National Academy of Sciences of the United States of America 96 (25): 14378-14382. 7 December 1999

Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes.
McDowell, T.L., Gibbons, R.J., Sutherland, H., O'Rourke, D.M., Bickmore, W.A., Pombo, A. ORCID logoORCID: https://orcid.org/0000-0002-7493-6288, Turley, H., Gatter, K., Picketts, D.J., Buckle, V.J., Chapman, L., Rhodes, D. and Higgs, D.R.
Proceedings of the National Academy of Sciences of the United States of America 96 (24): 13983-8. 23 November 1999

Two-dimensional IR correlation spectroscopy: Sequential events in the unfolding process of the lamda Cro-V55C repressor protein.
Fabian, H., Mantsch, H.H. and Schultz, C.P.
Proceedings of the National Academy of Sciences of the United States of America 96 : 13153-13158. 9 November 1999

Neutral evolution of mutational robustness.
van Nimwegen, E., Crutchfield, J.P. and Huynen, M.
Proceedings of the National Academy of Sciences of the United States of America 96 : 9716-9720. 17 August 1999

Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases.
Beltinger, C., Fulda, S., Kammertoens, T. ORCID logoORCID: https://orcid.org/0000-0003-3309-5141, Meyer, E., Uckert, W. and Debatin, K.M.
Proceedings of the National Academy of Sciences of the United States of America 96 : 8699-8704. 20 July 1999

Separation of C/EBP alpha-mediated proliferation arrest and differentiation pathways.
Mueller, C., Alunni-Fabroni, M., Kowenz-Leutz, E., Mo, X.M., Tommasino, M. and Leutz, A. ORCID logoORCID: https://orcid.org/0000-0001-8259-927X
Proceedings of the National Academy of Sciences of the United States of America 96 : 7276-7281. 22 June 1999

Conformational variants of class II MHC/peptide complexes induced by N- and C-terminal extensions of minimal peptide epitopes.
Roetzschke, O., Falk, K., Mack, J., Lau, J.M., Jung, G. and Strominger, J.L.
Proceedings of the National Academy of Sciences of the United States of America 96 : 7445-7450. 22 June 1999

Unexpected abundance of self-splicing introns in the genome of bacteriophage Twort: introns in multiple genes, a single gene with three introns, and exon skipping by group I ribozymes.
Landthaler, M. ORCID logoORCID: https://orcid.org/0000-0002-1075-8734 and Shub, D.A.
Proceedings of the National Academy of Sciences of the United States of America 96 (12): 7005-7010. 8 June 1999

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology.
Scherzinger, E., Sittler, A., Schweiger, K., Heiser, V., Lurz, R., Hasenbank, R., Bates, G.P., Lehrach, H. and Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630
Proceedings of the National Academy of Sciences of the United States of America 96 (8): 4604-4609. 13 April 1999

Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen.
Schinke, M., Baltatu, O., Boehm, M., Peters, J., Rascher, W., Bricca, G., Lippoldt, A., Ganten, D. and Bader, M. ORCID logoORCID: https://orcid.org/0000-0003-4780-4164
Proceedings of the National Academy of Sciences of the United States of America 96 : 3975-3980. 30 March 1999

The Opitz syndrome gene product, MID1, associates with microtubules.
Schweiger, S., Foerster, J., Lehman, T., Suckow, V., Muller, Y.A., Walter, G., Davies, T., Porter, H., van Bokhoven, H., Lunt, P.W., Traub, P. and Ropers, H.H.
Proceedings of the National Academy of Sciences of the United States of America 96 : 2794-2799. 16 March 1999

Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes.
Baron, U., Schnappinger, D., Helbl, V., Gossen, M., Hillen, W. and Bujard, H.
Proceedings of the National Academy of Sciences of the United States of America 96 : 1013-1018. 2 February 1999

1998

A pyrimidine-rich exonic splicing suppressor binds multiple RNA splicing factors and inhibits spliceosome assembly.
Zheng, Z.M., Huynen, M. and Baker, C.C.
Proceedings of the National Academy of Sciences of the United States of America 95 (24): 14088-14093. 24 November 1998

Peptide design by artificial neural networks and computer-based evolutionary search.
Schneider, G., Schrodl, W., Wallukat, G., Mueller, J., Nissen, E., Roenspeck, W., Wrede, P. and Kunze, R.
Proceedings of the National Academy of Sciences of the United States of America 95 (21): 12179-12184. 13 October 1998

Copy number control of a transposable element, the I factor, a LINE-like element in Drosophila.
Chaboissiert, M.C., Bucheton, A. and Finnegan, D.J.
Proceedings of the National Academy of Sciences of the United States of America 95 (20): 11781-11785. 29 September 1998

A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets.
Sander, M. ORCID logoORCID: https://orcid.org/0000-0001-5308-7785, Griffen, S.C., Huang, J. and German, M.S.
Proceedings of the National Academy of Sciences of the United States of America 95 (20): 11572-7. 29 September 1998

Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells.
Luo, G., Ivics, Z. ORCID logoORCID: https://orcid.org/0000-0002-7803-6658, Izsvak, Z. ORCID logoORCID: https://orcid.org/0000-0002-2053-2384 and Bradley, A.
Proceedings of the National Academy of Sciences of the United States of America 95 (18): 10769-10773. 1 September 1998

Deletion of long-range regulatory elements upstream of SOX9 causes campomelic dysplasia.
Wunderle, V.M., Critcher, R., Hastie, N., Goodfellow, P.N. and Schedl, A.
Proceedings of the National Academy of Sciences of the United States of America 95 (18): 10649-10654. 1 September 1998

The Drosophila LIM-only gene, dLMO, is mutated in Beadex alleles and might represent an evolutionarily conserved function in appendage development.
Zeng, C., Justice, N.J., Abdelilah, S., Chan, Y.M., Jan, L.Y. and Jan, Y.N.
Proceedings of the National Academy of Sciences of the United States of America 95 (18): 10637-10642. 1 September 1998

ClC-5, the chloride channel mutated in Dent's disease, colocalizes with the proton pump in endocytotically active kidney cells.
Guenther, W., Luechow, A., Cluzeaud, F., Vandewalle, A. and Jentsch, T.J. ORCID logoORCID: https://orcid.org/0000-0002-3509-2553
Proceedings of the National Academy of Sciences of the United States of America 95 (14): 8075-8080. 7 July 1998

Structure and function of the Bacillus hybrid enzyme GluXyn-1: Native-like jellyroll fold preserved after insertion of autonomous globular domain.
Ay, J., Goetz, F., Borriss, R. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 95 (12): 6613-6618. 9 June 1998

Huntingtin aggregation monitored by dynamic light scattering.
Georgalis, Y., Starikov, E.B., Hollenbach, B., Lurz, R., Scherzinger, E., Saenger, W., Lehrach, H. and Wanker, E.E. ORCID logoORCID: https://orcid.org/0000-0001-8072-1630
Proceedings of the National Academy of Sciences of the United States of America 95 (11): 6118-6121. 26 May 1998

Measuring genome evolution.
Huynen, M.A. and Bork, P.
Proceedings of the National Academy of Sciences of the United States of America 95 (11): 5849-5856. 26 May 1998

SMART, a simple modular architecture research tool: Identification of signaling domains.
Schultz, J., Milpetz, F., Bork, P. and Ponting, C.P.
Proceedings of the National Academy of Sciences of the United States of America 95 (11): 5857-5864. 26 May 1998

A substrate of the centisome 63 type III protein secretion system of Salmonella typhimurium is encoded by a cryptic bacteriophage.
Hardt, W.D., Urlaub, H. and Galan, J.E.
Proceedings of the National Academy of Sciences of the United States of America 95 (5): 2574-2579. 3 March 1998

1997

Superactivation of an immune response triggered by oligomerized T cell epitopes.
Roetzschke, O., Falk, K. and Strominger, J.L.
Proceedings of the National Academy of Sciences of the United States of America 94 (26): 14642-14647. 23 December 1997

Insulin-like growth factors-I and -II differentially regulate endogenous acetylcholine release from the rat hippocampal formation.
Kar, S., Seto, D., Dore, S., Hanisch, U. and Quirion, R.
Proceedings of the National Academy of Sciences of the United States of America 94 (25): 14054-14059. 9 December 1997

Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein.
Dhordain, P., Albagli, O., Lin, R.J., Ansieau, S., Quief, S., Leutz, A. ORCID logoORCID: https://orcid.org/0000-0001-8259-927X, Kerckaert, J.P., Evans, R.M. and Leprince, D.
Proceedings of the National Academy of Sciences of the United States of America 94 (20): 10762-10767. 30 September 1997

Genetic influence on neurogenesis in the dentate gyrus of adult mice.
Kempermann, G. ORCID logoORCID: https://orcid.org/0000-0002-5304-4061, Kuhn, H.G. and Gage, F.H.
Proceedings of the National Academy of Sciences of the United States of America 94 (19): 10409-10414. 16 September 1997

Transmembrane topology of a CLC chloride channel.
Schmidt-Rose, T. and Jentsch, T.J. ORCID logoORCID: https://orcid.org/0000-0002-3509-2553
Proceedings of the National Academy of Sciences of the United States of America 94 (14): 7633-7638. 8 July 1997

Frequency-domain techniques enhance optical mammography. Initial clinical results.
Franceschini, M.A., Moesta, K.T., Fantini, S., Gaida, G., Gratton, E., Jess, H., Mantulin, W.W., Seeber, M., Schlag, P.M. and Kaschke, M.
Proceedings of the National Academy of Sciences of the United States of America 94 (12): 6468-6473. 10 June 1997

Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs.
Mushegian, A.R., Bassett, D.E., Boguski, M.S., Bork, P. and Koonin, E.V.
Proceedings of the National Academy of Sciences of the United States of America 94 : 5831-5836. 1 January 1997

1996

Intrastriatally injected c-fos antisense oligonucleotide interferes with striatonigral but not striatopallidal gamma-aminobutyric acid transmission in the conscious rat.
Sommer, W., Rimondini, R., O'Connor, W., Hansson, A., Ungerstedt, U. and Fuxe, K.
Proceedings of the National Academy of Sciences of the United States of America 93 (24): 14134-14139. 26 November 1996

Heteromultimeric CLC chloride channels with novel properties.
Lorenz, C., Pusch, M. and Jentsch, T.J. ORCID logoORCID: https://orcid.org/0000-0002-3509-2553
Proceedings of the National Academy of Sciences of the United States of America 93 (23): 13362-13366. 12 November 1996

Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene.
Tucker, K.L., Talbot, D., Lee, M.A., Leonhardt, H. ORCID logoORCID: https://orcid.org/0000-0002-5086-6449 and Jaenisch, R.
Proceedings of the National Academy of Sciences of the United States of America 93 (23): 12920-12925. 12 November 1996

Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice.
Kistner, A., Gossen, M., Zimmermann, F., Jerecic, J., Ullmer, C., Lubbert, H. and Bujard, H.
Proceedings of the National Academy of Sciences of the United States of America 93 (20): 10933-10938. 1 October 1996

Defective forebrain development in mice lacking gp330/megalin.
Willnow, T.E. ORCID logoORCID: https://orcid.org/0000-0001-9515-7921, Hilpert, J., Armstrong, S.A., Rohlmann, A., Hammer, R.E., Burns, D.K. and Herz, J.
Proceedings of the National Academy of Sciences of the United States of America 93 (16): 8460-8464. 6 August 1996

Identification of functional domains and evolution of Tc1-like transposable elements.
Ivics, Z. ORCID logoORCID: https://orcid.org/0000-0002-7803-6658, Izsvak, Z. ORCID logoORCID: https://orcid.org/0000-0002-2053-2384, Minter, A. and Hackett, P.B.
Proceedings of the National Academy of Sciences of the United States of America 93 (10): 5008-5013. 14 May 1996

Induction of cellular immunity in chimpanzees to human tumor associated antigen mucin by vaccination with MUC-1 cDNA-transfected Epstein-Barr virus-immortalized autologous B cells.
Pecher, G. and Finn, O.J.
Proceedings of the National Academy of Sciences of the United States of America 93 (4): 1699-1704. 20 February 1996

DANA elements: a family of composite, tRNA-derived short interspersed DNA elements associated with mutational activities in zebrafish (Danio rerio).
Izsvak, Z. ORCID logoORCID: https://orcid.org/0000-0002-2053-2384, Ivics, Z. ORCID logoORCID: https://orcid.org/0000-0002-7803-6658, Garcia-Estefania, D., Fahrenkrug, S.C. and Hackett, P.B.
Proceedings of the National Academy of Sciences of the United States of America 93 (3): 1077-1081. 6 February 1996

1995

Efficient gene transfer into human hepatocytes by baculovirus vectors.
Hofmann, C., Sandig, V., Jennings, G., Rudolph, M., Schlag, P.M. and Strauss, M.
Proceedings of the National Academy of Sciences of the United States of America 92 (22): 10099-10103. 24 October 1995

VIP21/caveolin is a cholesterol-binding protein.
Murata, M., Peraenen, J., Schreiner, R., Wieland, F., Kurzchalia, T.V. and Simons, K.
Proceedings of the National Academy of Sciences of the United States of America 92 (22): 10339-10343. 24 October 1995

Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10.
Kreutz, R., Hübner, N. ORCID logoORCID: https://orcid.org/0000-0002-1218-6223, James, M.R., Bihoreau, M.T., Gauguier, D., Lathrop, G.M., Ganten, D. and Lindpaintner, K.
Proceedings of the National Academy of Sciences of the United States of America 92 (19): 8778-8782. 12 September 1995

Functional expression of low density lipoprotein receptor- related protein is controlled by receptor-associated protein in vivo.
Willnow, T.E. ORCID logoORCID: https://orcid.org/0000-0001-9515-7921, Armstrong, S.A., Hammer, R.E. and Herz, J.
Proceedings of the National Academy of Sciences of the United States of America 92 (10): 4537-4541. 9 May 1995

Lactation is disrupted by alpha-lactalbumin deficiency and can by restored by human alpha-lactalbumin gene replacement in mice.
Stacey, A., Schnieke, A., Kerr, M., Scott, A., McKee, C., Cottingham, I., Binas, B., Wilde, C. and Colman, A.
Proceedings of the National Academy of Sciences of the United States of America 92 (7): 2835-2839. 28 March 1995

A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development.
Riethmacher, D., Brinkmann, V. and Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 92 (3): 855-859. 31 January 1995

Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.
Weidner, K.M., Sachs, M., Riethmacher, D. and Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 92 : 2597-2601. 1 January 1995

1994

Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.
Furth, P.A., Onge, S.T., Boger, H., Gruss, P., Gossen, M., Kistner, A., Bujard, H. and Hennighausen, L.
Proceedings of the National Academy of Sciences of the United States of America 91 (20): 9302-9306. 27 September 1994

Divergent T-cell cytokine patterns in inflammatory arthritis.
Simon, A.K. ORCID logoORCID: https://orcid.org/0000-0002-4077-7995, Seipelt, E. and Sieper, J.
Proceedings of the National Academy of Sciences of the United States of America 91 (18): 8562-6. 30 August 1994

Two highly homologous members of the ClC chloride channel family in both rat and human kidney.
Kieferle, S., Fong, P., Bens, M., Vandewalle, A. and Jentsch, T.J. ORCID logoORCID: https://orcid.org/0000-0002-3509-2553
Proceedings of the National Academy of Sciences of the United States of America 91 (15): 6943-6947. 19 July 1994

Crystal structure of CspA, the major cold shock protein of Escherichia coli.
Schindelin, H., Jiang, W., Inouye, M. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 91 (11): 5119-5123. 24 May 1994

Cyclin D1 expression is regulated by the retinoblastoma protein.
Mueller, H., Lukas, J., Schneider, A., Warthoe, P., Bartek, J., Eilers, M. and Strauss, M.
Proceedings of the National Academy of Sciences of the United States of America 91 (8): 2945-2949. 12 April 1994

E-cadherin gene mutations in human gastric carcinoma cell lines.
Oda, T., Kanai, Y., Oyama, T., Yoshiura, K., Shimoyama, Y., Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829, Sugimura, T. and Hirohashi, S.
Proceedings of the National Academy of Sciences of the United States of America 91 (5): 1858-1862. 1 March 1994

A subset of HLA-B27 molecules contains peptides much longer than nonamers.
Urban, R.G., Chicz, R.M., Lane, W.S., Strominger, J.L., Rehm, A. ORCID logoORCID: https://orcid.org/0000-0001-7490-1950, Kenter, M.J., UytdeHaag, F.G., Ploegh, H., Uchanska-Ziegler, B. and Ziegler, A.
Proceedings of the National Academy of Sciences of the United States of America 91 (4): 1534-1538. 15 February 1994

Role of adrenal renin in the regulation of adrenal steroidogenesis corticotropin.
Sander, M. ORCID logoORCID: https://orcid.org/0000-0001-5308-7785, Ganten, D. and Mellon, S.H.
Proceedings of the National Academy of Sciences of the United States of America 91 (1): 148-152. 4 January 1994

Native-like in vivo folding of a circularly permuted jellyroll protein shown by crystal structure analysis.
Hahn, M., Piotukh, K., Borriss, R. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 91 : 10417-10421. 1 January 1994

Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development.
Meyer, D. and Birchmeier, C. ORCID logoORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 91 : 1064-1068. 1 January 1994

1993

Allele-specific peptide ligand motifs of HLA-C molecules.
Falk, K., Roetzschke, O., Grahovac, B., Schendel, D., Stevanovic, S., Gnau, V., Jung, G., Strominger, J.L. and Rammensee, H.G.
Proceedings of the National Academy of Sciences of the United States of America 90 (24): 12005-12009. 15 December 1993

Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.
Corral, J., Forster, A., Thompson, S., Lampert, F., Kaneko, Y., Slater, R., Kroes, W.G., van der Schoot, C.E., Ludwig, W.D., Karpas, A., Pocock, C., Cotter, F. and Rabitts, T.H.
Proceedings of the National Academy of Sciences of the United States of America 90 (18): 8538-8542. 15 September 1993

A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2.
Thierfelder, L.H., MacRae, C., Watkins, H., Tomfohrde, J., Williams, M., McKenna, W., Bohm, K., Noeske, G., Schlepper, M. and Bowcock, A.
Proceedings of the National Academy of Sciences of the United States of America 90 (13): 6270-6274. 1 July 1993

Mechanisms of rejection induced by tumor cell-targeted gene transfer of interleukin 2, interleukin 4, interleukin 7, tumor necrosis factor, or interferon-gamma.
Hock, H., Dorsch, M., Kunzendorf, U., Qin, Z., Diamantstein, T. and Blankenstein, T. ORCID logoORCID: https://orcid.org/0000-0002-3357-4321
Proceedings of the National Academy of Sciences of the United States of America 90 (7): 2774-2778. 1 April 1993

Molecular and active-site structure of a Bacillus (1-3,1-4)-beta-glucanase.
Keitel, T., Simon, O., Borriss, R. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 90 : 5287-5291. 1 January 1993

1992

An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins.
Bork, P., Sander, C. and Valencia, A.
Proceedings of the National Academy of Sciences of the United States of America 89 (16): 7290-7294. 15 August 1992

Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes.
Ganten, D., Wagner, J., Zeh, K., Bader, M. ORCID logoORCID: https://orcid.org/0000-0003-4780-4164, Michel, J.B., Paul, M., Zimmermann, F., Ruf, P., Hilgenfeldt, U., Ganten, U., Kaling, M., Bachmann, S., Fukamizu, A., Mullins, J.J. and Murakami, K.
Proceedings of the National Academy of Sciences of the United States of America 89 : 7806-7810. August 1992

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
Gossen, M. and Bujard, H.
Proceedings of the National Academy of Sciences of the United States of America 89 (12): 5547-5551. 15 June 1992

Proposed acquisition of an animal protein domain by bacteria.
Bork, P. and Doolittle, R.F.
Proceedings of the National Academy of Sciences of the United States of America 89 : 8990-8994. 1 January 1992

A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis.
Hartmann, G., Naldini, L., Weidner, K.M., Sachs, M., Vigna, E., Comoglio, P.M. and Birchmeier, W. ORCID logoORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 89 : 11574-11578. 1 January 1992

The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappaB DNA binding.
Hatada, E.N., Nieters, A., Wulczyn, F.G., Naumann, M., Meyer, R., Nucifora, G., McKeithan, T.W. and Scheidereit, C. ORCID logoORCID: https://orcid.org/0000-0002-0446-6129
Proceedings of the National Academy of Sciences of the United States of America 89 (6): 2489-2493. 1 January 1992

1991

Completely functional double-barreled chloride channel expressed from a single Torpedo cDNA.
Bauer, C.K., Steinmeyer, K., Schwarz, J.R. and Jentsch, T.J. ORCID logoORCID: https://orcid.org/0000-0002-3509-2553
Proceedings of the National Academy of Sciences of the United States of America 88 (24): 11052-11056. 15 December 1991

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