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Article

Structure and function of the hippocampal CA3 module.
Sammons, R.P. and Vezir, M. and Moreno-Velasquez, L. and Cano, G. and Orlando, M. and Sievers, M. and Grasso, E. and Metodieva, V.D. and Kempter, R. and Schmidt, H. and Schmitz, D.
Proceedings of the National Academy of Sciences of the United States of America 121 (6): e2312281120. 6 February 2024

A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea.
Mottaghinia, S. and Stenzel, S. and Tsangaras, K. and Nikolaidis, N. and Laue, M. and Müller, K. and Hölscher, H. and Löber, U. and McEwen, G.K. and Donnellan, S.C. and Rowe, K.C. and Aplin, K.P. and Goffinet, C. and Greenwood, A.D.
Proceedings of the National Academy of Sciences of the United States of America 121 (6): e2220392121. 1 February 2024

Germline C1GALT1C1 mutation causes a multisystem chaperonopathy.
Erger, F. and Aryal, R.P. and Reusch, B. and Matsumoto, Y. and Meyer, R. and Zeng, J. and Knopp, C. and Noel, M. and Muerner, L. and Wenzel, A. and Kohl, S. and Tschernoster, N. and Rappl, G. and Rouvet, I. and Schröder-Braunstein, J. and Seibert, F.S. and Thiele, H. and Häusler, M.G. and Weber, L.T. and Büttner-Herold, M. and Elbracht, M. and Cummings, S.F. and Altmüller, J. and Habbig, S. and Cummings, R.D. and Beck, B.B.
Proceedings of the National Academy of Sciences of the United States of America 120 (22): e2211087120. 30 May 2023

TapA acts as specific chaperone in TasA filament formation by strand complementation.
Roske, Y. and Lindemann, F. and Diehl, A. and Cremer, N. and Higman, V.A. and Schlegel, B. and Leidert, M. and Driller, K. and Turgay, K. and Schmieder, P. and Heinemann, U. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 120 (17): e2217070120. 25 April 2023

Mouse models of human multiple myeloma subgroups.
Winkler, W. and Farré Díaz, C. and Blanc, E. and Napieczynska, H. and Langner, P. and Werner, M. and Walter, B. and Wollert-Wulf, B. and Yasuda, T. and Heuser, A. and Beule, D. and Mathas, S. and Anagnostopoulos, I. and Rosenwald, A. and Rajewsky, K. and Janz, M.
Proceedings of the National Academy of Sciences of the United States of America 120 (10): e2219439120. 7 March 2023

Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
Petrović, S. and Roske, Y. and Rami, B. and Phan, M.H.Q. and Panakova, D. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 120 (4): e2208941120. 24 January 2023

Different classes of genomic inserts contribute to human antibody diversity.
Lebedin, M. and Foglierini, M. and Khorkova, S. and Vázquez García, C. and Ratswohl, C. and Davydov, A.N. and Turchaninova, M.A. and Daubenberger, C. and Chudakov, D.M. and Lanzavecchia, A. and de la Rosa, K.
Proceedings of the National Academy of Sciences of the United States of America 119 (36): e2205470119. 6 September 2022

Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6.
Cockman, M.E. and Sugimoto, Y. and Pegg, H.B. and Masson, N. and Salah, E. and Tumber, A. and Flynn, H.R. and Kirkpatrick, J.M. and Schofield, C.J. and Ratcliffe, P.J.
Proceedings of the National Academy of Sciences of the United States of America 119 (32): e2201483119. 9 August 2022

Functional modulation of PTH1R activation and signaling by RAMP2.
Nemec, K. and Schihada, H. and Kleinau, G. and Zabel, U. and Grushevsky, E.O. and Scheerer, P. and Lohse, M.J. and Maiellaro, I.
Proceedings of the National Academy of Sciences of the United States of America 119 (32): e2122037119. 9 August 2022

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model.
Axelsson Raja, A. and Wakimoto, H. and DeLaughter, D.M. and Reichart, D. and Gorham, J. and Conner, D.A. and Lun, M. and Probst, C.K. and Sakai, N. and Knipe, R.S. and Montesi, S.B. and Shea, B. and Adam, L.P. and Leinwand, L.A. and Wan, W. and Choi, E.S. and Lindberg, E.L. and Patone, G. and Noseda, M. and Hübner, N. and Seidman, C.E. and Tager, A.M. and Seidman, J.G. and Ho, C.Y.
Proceedings of the National Academy of Sciences of the United States of America 119 (28): e2204174119. 12 July 2022

Brain-wide interactions during hippocampal sharp wave ripples.
Nitzan, N. and Swanson, R. and Schmitz, D. and Buzsáki, G.
Proceedings of the National Academy of Sciences of the United States of America 119 (20): e2200931119. 17 May 2022

NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
Doffo, J. and Bamopoulos, S.A. and Köse, H. and Orben, F. and Zang, C. and Pons, M. and den Dekker, A.T. and Brouwer, R.W.W. and Baluapuri, A. and Habringer, S. and Reichert, M. and Illendula, A. and Krämer, O.H. and Schick, M. and Wolf, E. and van IJcken, W.F.J. and Esposito, I. and Keller, U. and Schneider, G. and Wirth, M.
Proceedings of the National Academy of Sciences of the United States of America 119 (9): e2105691119. 1 March 2022

ENHANCED GRAVITROPISM 2 encodes a STERILE ALPHA MOTIF–containing protein that controls root growth angle in barley and wheat.
Kirschner, G.K. and Rosignoli, S. and Guo, L. and Vardanega, I. and Imani, J. and Altmüller, J. and Milner, S.G. and Balzano, R: and Nagel, K.A. and Pflugfelder, D. and Forestan, C. and Bovina, R. and Koller, R. and Stöcker, T.G. and Mascher, M. and Simmonds, J. and Uauy, C. and Schoof, H. and Tuberosa, R. and Salvi, S. and Hochholdinger, F.
Proceedings of the National Academy of Sciences of the United States of America 118 (35): e2101526118. 31 August 2021

The magnitude of germinal center reactions is restricted by a fixed number of preexisting niches.
Avancena, P. and Song, T. and Yao, Y. and Fehlner-Peach, H. and Diamond, B. and Gu, H. and Rajewsky, K. and Zou, Y.R.
Proceedings of the National Academy of Sciences of the United States of America 118 (30): e2100576118. 27 July 2021

Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor.
Ganichkin, O.M. and Vancraenenbroeck, R. and Rosenblum, G. and Hofmann, H. and Mikhailov, A.S. and Daumke, O. and Noel, J.K.
Proceedings of the National Academy of Sciences of the United States of America 118 (28): e2101144118. 13 July 2021

Skin sodium is increased in male patients with multiple sclerosis and related animal models.
Huhn, K. and Linz, P. and Pemsel, F. and Michalke, B. and Seyferth, S. and Kopp, C. and Chaudri, M.A. and Rothhammer, V. and Dörfler, A. and Uder, M. and Nagel, A.M. and Müller, D.N. and Waschbisch, A. and Lee, D.H. and Bäuerle, T. and Linker, R.A. and Haase, S.
Proceedings of the National Academy of Sciences of the United States of America 118 (28): e2102549118. 13 July 2021

Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes.
Bathe-Peters, M. and Gmach, P. and Boltz, H.H. and Einsiedel, J. and Gotthardt, M. and Hübner, H. and Gmeiner, P. and Lohse, M.J. and Annibale, P.
Proceedings of the National Academy of Sciences of the United States of America 118 (23): e2101119118. 8 June 2021

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J. and Grinat, J. and Kosel, F. and Liu, L. and Kunz, S. and Vidal, R.O. and Keil, M. and Haybaeck, J. and Robine, S. and Louvard, D. and Regenbrecht, C. and Sporbert, A. and Sauer, S. and von Eyss, B. and Sigal, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 118 (22): e2019699118. 1 June 2021

Reconstitution of β-adrenergic regulation of Ca(V)1.2: Rad-dependent and Rad-independent protein kinase A mechanisms.
Katz, M. and Subramaniam, S. and Chomsky-Hecht, O. and Tsemakhovich, V. and Flockerzi, V. and Klussmann, E. and Hirsch, J.A. and Weiss, S. and Dascal, N.
Proceedings of the National Academy of Sciences of the United States of America 118 (21): e2100021118. 17 May 2021

Enhanced Ca(2+) signaling, mild primary aldosteronism, and hypertension in a familial hyperaldosteronism mouse model (Cacna1h(M1560V/+)).
Seidel, E. and Schewe, J. and Zhang, J. and Dinh, H.A. and Forslund, S.K. and Markó, L. and Hellmig, N. and Peters, J. and Muller, D.N. and Lifton, R.P. and Nottoli, T. and Stölting, G. and Scholl, U.I.
Proceedings of the National Academy of Sciences of the United States of America 118 (17): e2014876118. 27 April 2021

On the adhesion-velocity relation and length adaptation of motile cells on stepped fibronectin lanes.
Schreiber, C. and Amiri, B. and Heyn, J.C.J. and Rädler, J.O. and Falcke, M.
Proceedings of the National Academy of Sciences of the United States of America 118 (4): e2009959118. 26 January 2021

A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions.
Rodríguez de los Santos, M. and Rivalan, M. and David, F.S. and Stumpf, A. and Pitsch, J. and Tsortouktzidis, D. and Velasquez, L.M. and Voigt, A. and Schilling, K. and Mattei, D. and Long, M. and Vogt, G. and Knaus, A. and Fischer-Zirnsak, B. and Wittler, L. and Timmermann, B. and Robinson, P.N. and Horn, D. and Mundlos, S. and Kornak, U. and Becker, A.J. and Schmitz, D. and Winter, Y. and Krawitz, P.M.
Proceedings of the National Academy of Sciences of the United States of America 118 (2): e2014481118. 12 January 2021

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
Ostkamp, P. and Salmen, A. and Pignolet, B. and Görlich, D. and Andlauer, T.F.M. and Schulte-Mecklenbeck, A. and Gonzalez-Escamilla, G. and Bucciarelli, F. and Gennero, I. and Breuer, J. and Antony, G. and Schneider-Hohendorf, T. and Mykicki, N. and Bayas, A. and Then Bergh, F. and Bittner, S. and Hartung, H.P. and Friese, M.A. and Linker, R.A. and Luessi, F. and Lehmann-Horn, K. and Mühlau, M. and Paul, F. and Stangel, M. and Tackenberg, B. and Tumani, H. and Warnke, C. and Weber, F. and Wildemann, B. and Zettl, U.K. and Ziemann, U. and Müller-Myhsok, B. and Kümpfel, T. and Klotz, L. and Meuth, S.G. and Zipp, F. and Hemmer, B. and Hohlfeld, R. and Brassat, D. and Gold, R. and Gross, C.C. and Lukas, C. and Groppa, S. and Loser, K. and Wiendl, H. and Schwab, N.
Proceedings of the National Academy of Sciences of the United States of America 118 (1): e2018457118. 5 January 2021

Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Barone, M. and Müller, M. and Chiha, S. and Ren, J. and Albat, D. and Soicke, A. and Dohmen, S. and Klein, M. and Bruns, J. and van Dinther, M. and Opitz, R. and Lindemann, P. and Beerbaum, M. and Motzny, K. and Roske, Y. and Schmieder, P. and Volkmer, R. and Nazaré, M. and Heinemann, U. and Oschkinat, H. and Ten Dijke, P. and Schmalz, H.G. and Kühne, R.
Proceedings of the National Academy of Sciences of the United States of America 117 (47): 29684-29690. 24 November 2020

Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists.
Işbilir, A. and Möller, J. and Arimont, M. and Bobkov, V. and Perpiñá-Viciano, C. and Hoffmann, C. and Inoue, A. and Heukers, R. and de Graaf, C. and Smit, M.J. and Annibale, P. and Lohse, M.J.
Proceedings of the National Academy of Sciences of the United States of America 117 (46): 29144-29154. 17 November 2020

The transcription factor C/EBPβ orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions.
Scholz, F. and Grau, M. and Menzel, L. and Graband, A. and Zapukhlyak, M. and Leutz, A. and Janz, M. and Lenz, G. and Rehm, A. and Höpken, U.E.
Proceedings of the National Academy of Sciences of the United States of America 117 (42): 26328-26339. 20 October 2020

Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis.
Sommermann, T. and Yasuda, T. and Ronen, J. and Wirtz, T. and Weber, T. and Sack, U. and Caeser, R. and Zhang, J. and Li, X. and Chu, V.T. and Jauch, A. and Unger, K. and Hodson, D.J. and Akalin, A. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 117 (25): 14421-14432. 23 June 2020

EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake.
Matthaeus, C. and Lahmann, I. and Kunz, S. and Jonas, W. and Melo, A.A. and Lehmann, M. and Larsson, E. and Lundmark, R. and Kern, M. and Blüher, M. and Olschowski, H. and Kompa, J. and Brügger, B. and Müller, D.N. and Haucke, V. and Schürmann, A. and Birchmeier, C. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 117 (13): 7471-7481. 31 March 2020

Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice.
Wenzel, J. and Hansen, C.E. and Bettoni, C. and Vogt, M.A. and Lembrich, B. and Natsagdorj, R. and Huber, G. and Brands, J. and Schmidt, K. and Assmann, J.C. and Stölting, I. and Saar, K. and Sedlacik, J. and Fiehler, J. and Ludewig, P. and Wegmann, M. and Feller, N. and Richter, M. and Müller-Fielitz, H. and Walther, T. and König, G.M. and Kostenis, E. and Raasch, W. and Hübner, N. and Gass, P. and Offermanns, S. and de Wit, C. and Wagner, C.A. and Schwaninger, M.
Proceedings of the National Academy of Sciences of the United States of America 117 (3): 1753-1761. 21 January 2020

Resolving titin's lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes.
Rudolph, F. and Hüttemeister, J. and da Silva Lopes, K. and Jüttner, R. and Yu, L. and Bergmann, N. and Friedrich, D. and Preibisch, S. and Wagner, E. and Lehnart, S.E. and Gregorio, C.C. and Gotthardt, M.
Proceedings of the National Academy of Sciences of the United States of America 116 (50): 25126-25136. 10 December 2019

Human-specific tandem repeat expansion and differential gene expression during primate evolution.
Sulovari, A. and Li, R. and Audano, P.A. and Porubsky, D. and Vollger, M.R. and Logsdon, G.A. and Warren, W.C. and Pollen, A.A. and Chaisson, M.J.P. and Eichler, E.E.
Proceedings of the National Academy of Sciences of the United States of America 116 (46): 23243-23253. 12 November 2019

Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger, K.J. and Neukam, M. and Tattikota, S.G. and Qadri, F. and Puchkov, D. and Willmes, D.M. and Wurmsee, S. and Geisberger, S. and Dechend, R. and Raile, K. and Kurth, T. and Nguyen, G. and Poy, M.N. and Solimena, M. and Muller, D.N. and Birkenfeld, A.L.
Proceedings of the National Academy of Sciences of the United States of America 116 (40): 19983-19988. 1 October 2019

Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.
Omar, F. and Findlay, J.E. and Carfray, G. and Allcock, R.W. and Jiang, Z. and Moore, C. and Muir, A.L. and Lannoy, M. and Fertig, B.A. and Mai, D. and Day, J.P. and Bolger, G. and Baillie, G.S. and Schwiebert, E. and Klussmann, E. and Pyne, N.J. and Ong, A.C.M. and Bowers, K. and Adam, J.M. and Adams, D.R. and Houslay, M.D. and Henderson, D.J.P.
Proceedings of the National Academy of Sciences of the United States of America 116 (27): 13320-13329. 2 July 2019

Preformed chromatin topology assists transcriptional robustness of Shh during limb development.
Paliou, C. and Guckelberger, P. and Schöpflin, R. and Heinrich, V. and Esposito, A. and Chiariello, A.M. and Bianco, S. and Annunziatella, C. and Helmuth, J. and Haas, S. and Jerković, I. and Brieske, N. and Wittler, L. and Timmermann, B. and Nicodemi, M. and Vingron, M. and Mundlos, S. and Andrey, G.
Proceedings of the National Academy of Sciences of the United States of America 116 (25): 12390-12399. 18 June 2019

Insights into IgM-mediated complement activation based on in situ structures of IgM-C1-C4b.
Sharp, T.H. and Boyle, A.L. and Diebolder, C.A. and Kros, A. and Koster, A. and Gros, P.
Proceedings of the National Academy of Sciences of the United States of America 116 (24): 11900-11905. 11 June 2019

Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement.
Grushevskyi, E.O. and Kukaj, T. and Schmauder, R. and Bock, A. and Zabel, U. and Schwabe, T. and Benndorf, K. and Lohse, M.J.
Proceedings of the National Academy of Sciences of the United States of America 116 (20): 10150-10155. 14 May 2019

MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis.
Kotelnikova, E. and Kiani, N.A. and Messinis, D. and Pertsovskaya, I. and Pliaka, V. and Bernardo-Faura, M. and Rinas, M. and Vila, G. and Zubizarreta, I. and Pulido-Valdeolivas, I. and Sakellaropoulos, T. and Faigle, W. and Silberberg, G. and Masso, M. and Stridh, P. and Behrens, J. and Olsson, T. and Martin, R. and Paul, F. and Alexopoulos, L.G. and Saez-Rodriguez, J. and Tegner, J. and Villoslada, P.
Proceedings of the National Academy of Sciences of the United States of America 116 (19): 9671-9676. 7 May 2019

Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice.
Hernandez-Miranda, L.R. and Ibrahim, D.M. and Ruffault, P.L. and Larrosa, M. and Balueva, K. and Müller, T. and de Weerd, W. and Stolte-Dijkstra, I. and Hostra, R.M.W. and Brunet, J.F. and Fortin, G. and Mundlos, S. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 115 (51): 13021-13026. 18 December 2018

Atomistic simulations indicate the functional loop-to-coiled-coil transition in influenza hemagglutinin is not downhill.
Lin, X. and Noel, J.K. and Wang, Q. and Ma, J. and Onuchic, J.N.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): E7905-E7913. 21 August 2018

Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion.
Löber, U. and Hobbs, M. and Dayaram, A. and Tsangaras, K. and Jones, K. and Alquezar-Planas, D.E. and Ishida, Y. and Meers, J. and Mayer, J. and Quedenau, C. and Chen, W. and Johnson, R.N. and Timms, P. and Young, P.R. and Roca, A.L. and Greenwood, A.D.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): 8609-8614. 21 August 2018

Structural changes of TasA in biofilm formation of Bacillus subtilis.
Diehl, A. and Roske, Y. and Ball, L. and Chowdhury, A. and Hiller, M. and Molière, N. and Kramer, R. and Stöppler, D. and Worth, C.L. and Schlegel, B. and Leidert, M. and Cremer, N. and Erdmann, N. and Lopez, D. and Stephanowitz, H. and Krause, E. and van Rossum, B.J. and Schmieder, P. and Heinemann, U. and Turgay, K. and Akbey, Ü. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 115 (13): 3237-3242. 27 March 2018

Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3.
Sowa, A.S. and Martin, E. and Martins, I.M. and Schmidt, J. and Depping, R. and Weber, J.J. and Rother, F. and Hartmann, E. and Bader, M. and Riess, O. and Tricoire, H. and Schmidt, T.
Proceedings of the National Academy of Sciences of the United States of America 115 (11): E2624-E2633. 13 March 2018

Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4(+) and CD8(+) T cell responses.
Choi, I.K. and Wang, Z. and Ke, Q. and Hong, M. and Qian, Y. and Zhao, X. and Liu, Y. and Kim, H.J. and Ritz, J. and Cantor, H. and Rajewsky, K. and Wucherpfennig, K.W. and Zhang, B.
Proceedings of the National Academy of Sciences of the United States of America 115 (4): E686-E695. January 2018

Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest.
Espinosa-Medina, I. and Jevans, B. and Boismoreau, F. and Chettouh, Z. and Enomoto, H. and Müller, T. and Birchmeier, C. and Burns, Alan J and Brunet, J.F.
Proceedings of the National Academy of Sciences of the United States of America 114 (45): 11980-11985. 7 November 2017

Necroptosis controls NET generation and mediates complement activation, endothelial damage, and autoimmune vasculitis.
Schreiber, A. and Rousselle, A. and Becker, J.U. and von Mässenhausen, A. and Linkermann, A. and Kettritz, R.
Proceedings of the National Academy of Sciences of the United States of America 114 (45): E9618-E9625. 7 November 2017

Identification of individuals by trait prediction using whole-genome sequencing data.
Lippert, C. and Sabatini, R. and Maher, M.C. and Kang, E.Y. and Lee, S. and Arikan, O. and Harley, A. and Bernal, A. and Garst, P. and Lavrenko, V. and Yocum, K. and Wong, T. and Zhu, M. and Yang, W.Y. and Chang, C. and Lu, T. and Lee, C.W.H. and Hicks, B. and Ramakrishnan, S. and Tang, H. and Xie, C. and Piper, J. and Brewerton, S. and Turpaz, Y. and Telenti, A. and Roby, R.K. and Och, F.J. and Venter, J.C.
Proceedings of the National Academy of Sciences of the United States of America 114 (38): 10166-10171. 19 September 2017

Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.
Hasegawa, E. and Inafuku, S. and Mulki, L. and Okunuki, Y. and Yanai, R. and Smith, K.E. and Kim, C.B. and Klokman, G. and Bielenberg, D.R. and Puli, N. and Falck, J.R. and Husain, D. and Miller, J.W. and Edin, M.L. and Zeldin, D.C. and Lee, K.S.S. and Hammock, B.D. and Schunck, W.H. and Connor, K.M.
Proceedings of the National Academy of Sciences of the United States of America 114 (36): E7545-E7553. 5 September 2017

Genetic identification of a hindbrain nucleus essential for innate vocalization.
Hernandez-Miranda, L.R. and Ruffault, P.L. and Bouvier, J.C. and Murray, A.J. and Morin-Surun, M.P. and Zampieri, N. and Cholewa-Waclaw, J.B. and Ey, E. and Brunet, J.F. and Champagnat, J. and Fortin, G. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 114 (30): 8095-8100. 25 July 2017

Structural insights into the activation mechanism of dynamin-like EHD ATPases.
Melo, A.A. and Hegde, B.G. and Shah, C. and Larsson, E. and Isas, J.M. and Kunz, S. and Lundmark, R. and Langen, R. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 114 (22): 5629-5634. 30 May 2017

Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.
Tobe, B.T.D. and Crain, A.M. and Winquist, A.M. and Calabrese, B. and Makihara, H. and Zhao, W.N. and Lalonde, J. and Nakamura, H. and Konopaske, G. and Sidor, M. and Pernia, C.D. and Yamashita, N. and Wada, M. and Inoue, Y. and Nakamura, F. and Sheridan, S.D. and Logan, R.W. and Brandel, M. and Wu, D. and Hunsberger, J. and Dorsett, L. and Duerr, C. and Basa, R.C.B. and McCarthy, M.J. and Udeshi, N.D. and Mertins, P. and Carr, S.A. and Rouleau, G.A. and Mastrangelo, L. and Li, J. and Gutierrez, G.J. and Brill, L.M. and Venizelos, N. and Chen, G. and Nye, J.S. and Manji, H. and Price, J.H. and McClung, C.A. and Akiskal, H.S. and Alda, M. and Chuang, D.M.M. and Coyle, J.T. and Liu, Y. and Teng, Y.D. and Ohshima, T. and Mikoshiba, K. and Sidman, R.L. and Halpain, S. and Haggarty, S.J. and Goshima, Y. and Snyder, E.Y.
Proceedings of the National Academy of Sciences of the United States of America 114 (22): E4462-E4471. 30 May 2017

Data-based modeling of drug penetration relates human skin barrier function to the interplay of diffusivity and free-energy profiles.
Schulz, R. and Yamamoto, K. and Klossek, A. and Flesch, R. and Hönzke, S. and Rancan, F. and Vogt, A. and Blume-Peytavi, U. and Hedtrich, S. and Schäfer-Korting, M. and Rühl, E. and Netz, R.R.
Proceedings of the National Academy of Sciences of the United States of America 114 (14): 3631-3636. 4 April 2017

Role of the receptor Mas in macrophage-mediated inflammation in vivo.
Hammer, A. and Yang, G. and Friedrich, J. and Kovacs, A. and Lee, D.H. and Grave, K. and Jörg, S. and Alenina, N. and Grosch, J. and Winkler, J. and Gold, R. and Bader, M. and Manzel, A. and Rump, L.C. and Müller, D.N. and Linker, R.A. and Stegbauer, J.
Proceedings of the National Academy of Sciences of the United States of America 113 (49): 14109-14114. 6 December 2016

Mouse model for acute Epstein-Barr virus infection.
Wirtz, T. and Weber, T. and Kracker, S. and Sommermann, T. and Rajewsky, K. and Yasuda, T.
Proceedings of the National Academy of Sciences of the United States of America 113 (48): 13821-13826. 29 November 2016

Stress-induced brain activity, brain atrophy, and clinical disability in multiple sclerosis.
Weygandt, M. and Meyer-Arndt, L. and Behrens, J.R. and Wakonig, K. and Bellmann-Strobl, J. and Ritter, K. and Scheel, M. and Brandt, A.U. and Labadie, C. and Hetzer, S. and Gold, S.M. and Paul, F. and Haynes, J.D.
Proceedings of the National Academy of Sciences of the United States of America 113 (47): 13444-13449. 22 November 2016

Super-resolution ribosome profiling reveals unannotated translation events in Arabidopsis.
Hsu, P.Y. and Calviello, L. and Wu, H.Y.L. and Li, F.W. and Rothfels, C.J. and Ohler, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 113 (45): E7126-E7135. 8 November 2016

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.
Chu, V.T. and Graf, R. and Wirtz, T. and Weber, T. and Favret, J. and Li, X. and Petsch, K. and Tran, N.T. and Sieweke, M.H. and Berek, C. and Kühn, R. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (44): 12514-12519. 1 November 2016

RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.
Grauel, M.K. and Maglione, M. and Reddy-Alla, S. and Willmes, C.G. and Brockmann, M.M. and Trimbuch, T. and Rosenmund, T. and Pangalos, M. and Vardar, G. and Stumpf, A. and Walter, A.M. and Rost, B.R. and Eickholt, B.J. and Haucke, V. and Schmitz, D. and Sigrist, S.J. and Rosenmund, C.
Proceedings of the National Academy of Sciences of the United States of America 113 (41): 11615-11620. 11 October 2016

Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination.
Braten, O. and Livneh, I. and Ziv, T. and Admon, A. and Kehat, I. and Caspi, L.H. and Gonen, H. and Bercovich, B. and Godzik, A. and Jahandideh, S. and Jaroszewski, L. and Sommer, T. and Kwon, Y.T. and Guharoy, M. and Tompa, P. and Ciechanover, A.
Proceedings of the National Academy of Sciences of the United States of America 113 (32): E4639-E4647. 9 August 2016

Superpriming of synaptic vesicles as a common basis for intersynapse variability and modulation of synaptic strength.
Taschenberger, H. and Woehler, A. and Neher, E.
Proceedings of the National Academy of Sciences of the United States of America 113 (31): E4548-E4557. 2 August 2016

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E. and Herzog, S. and Labi, V. and Yasuda, T. and Köchert, K. and Janz, M. and Villunger, A. and Schmidt-Supprian, M. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5065-5070. 3 May 2016

Tissue-specific DNA demethylation is required for proper B-cell differentiation and function.
Orlanski, S. and Labi, V. and Reizel, Y. and Spiro, A. and Lichtenstein, M. and Levin-Klein, R. and Koralov, S.B. and Skversky, Y. and Rajewsky, K. and Cedar, H. and Bergman, Y.
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5018-5023. 3 May 2016

Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders.
Wakabayashi, A. and Ulirsch, J.C. and Ludwig, L.S. and Fiorini, C. and Yasuda, M. and Choudhuri, A. and McDonel, P. and Zon, L.I. and Sankaran, V.G.
Proceedings of the National Academy of Sciences of the United States of America 113 (16): 4434-4439. 19 April 2016

Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections.
Cano, E. and Carmona, R. and Ruiz-Villalba, A. and Rojas, A. and Chau, Y.Y. and Wagner, K.D. and Wagner, N. and Hastie, N.D. and Munoz-Chapuli, R. and Perez-Pomares, J.M.
Proceedings of the National Academy of Sciences of the United States of America 113 (3): 656-661. 19 January 2016

The B-cell antigen receptor integrates adaptive and innate immune signals.
Otipoby, K.L. and Waisman, A. and Derudder, E. and Srinivasan, L. and Franklin, A. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 112 (39): 12145-12150. 29 September 2015

A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.
Opitz, R. and Mueller, M. and Reuter, C. and Barone, M. and Soicke, A. and Roske, Y. and Piotukh, K. and Huy, P. and Beerbaum, M. and Wiesner, B. and Beyermann, M. and Schmieder, P. and Freund, C. and Volkmer, R. and Oschkinat, H. and Schmalz, H.G. and Kuehne, R.
Proceedings of the National Academy of Sciences of the United States of America 112 (16): 5011-5016. 21 April 2015

VH replacement in primary immunoglobulin repertoire diversification.
Sun, A. and Novobrantseva, T.I. and Coffre, M. and Hewitt, S.L. and Jensen, K. and Skok, J.A. and Rajewsky, K. and Koralov, S.B.
Proceedings of the National Academy of Sciences of the United States of America 112 (5): E458-E466. 3 February 2015

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, S. and Bouhlel, M.A. and Cauchy, P. and Lamprecht, B. and Li, S. and Grau, M. and Hummel, F. and Köchert, K. and Anagnostopoulos, I. and Jöhrens, K. and Hummel, M. and Hiscott, J. and Wenzel, S.S. and Lenz, P. and Schneider, M. and Küppers, R. and Scheidereit, C. and Giefing, M. and Siebert, R. and Rajewsky, K. and Lenz, G. and Cockerill, P.N. and Janz, M. and Dörken, B. and Bonifer, C. and Mathas, S.
Proceedings of the National Academy of Sciences of the United States of America 111 (42): E4513-E4522. 21 October 2014

IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors.
Authier, H. and Billot, K. and Derudder, E. and Bordereaux, D. and Riviere, P. and Rodrigues-Ferreira, S. and Nahmias, C. and Baud, V.
Proceedings of the National Academy of Sciences of the United States of America 111 (41): 14794-14799. 14 October 2014

Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1.
Kayatekin, C. and Matlack, K.E.S. and Hesse, W.R. and Guan, Y. and Chakrabortee, S. and Russ, J. and Wanker, E.E. and Shah, J.V. and Lindquist, S.
Proceedings of the National Academy of Sciences of the United States of America 111 (33): 12085-12090. 19 August 2014

Cytochrome P450-generated metabolites derived from ω-3 fatty acids attenuate neovascularization.
Yanai, R. and Mulki, L. and Hasegawa, E. and Takeuchi, K. and Sweigard, H. and Suzuki, J. and Gaissert, P. and Vavvas, D.G. and Sonoda, K.H. and Rothe, M. and Schunck, W.H. and Miller, J.W. and Connor, K.M.
Proceedings of the National Academy of Sciences of the United States of America 111 (26): 9603-9608. 1 July 2014

Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.
Heuberger, J. and Kosel, F. and Qi, J. and Grossmann, K.S. and Rajewsky, K. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 111 (9): 3472-3477. 4 March 2014

Clostridium difficile toxin CDT hijacks microtubule organization and reroutes vesicle traffic to increase pathogen adherence.
Schwan, C. and Kruppke, A.S. and Nölke, T. and Schumacher, L. and Koch-Nolte, F. and Kudryashev, M. and Stahlberg, H. and Aktories, K.
Proceedings of the National Academy of Sciences of the United States of America 111 (6): 2313-2318. 11 February 2014

Electroconvulsive therapy-induced brain plasticity determines therapeutic outcome in mood disorders.
Dukart, J. and Regen, F. and Kherif, F. and Colla, M. and Bajbouj, M. and Heuser, I. and Frackowiak, R.S. and Draganski, B.
Proceedings of the National Academy of Sciences of the United States of America 111 (3): 1156-1161. 21 January 2014

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.
Rockich, B.E. and Hrycaj, S.M. and Shih, H.P. and Nagy, M.S. and Ferguson, M.A.H. and Kopp, J.L. and Sander, M. and Wellik, D.M. and Spence, J.R.
Proceedings of the National Academy of Sciences of the United States of America 110 (47): E4456-64. 19 November 2013

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T. and Stein, S. and Qi, J. and Wende, H. and Garratt, A.N. and Nave, K.A. and Birchmeier, C. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179. 5 November 2013

Reexposure to nicotine during withdrawal increases the pacemaking activity of cholinergic habenular neurons.
Goerlich, A. and Antolin-Fontes, B. and Ables, J.L. and Frahm, S. and Slimak, M.A. and Dougherty, J.D. and Ibanez-Tallon, I.
Proceedings of the National Academy of Sciences of the United States of America 110 (42): 17077-17082. 15 October 2013

GABA(B) autoreceptor-mediated cell type-specific reduction of inhibition in epileptic mice.
Dugladze, T. and Maziashvili, N. and Boergers, C. and Gurgenidze, S. and Haeussler, U. and Winkelmann, A. and Haas, C.A. and Meier, J.C. and Vida, I. and Kopell, N.J. and Gloveli, T.
Proceedings of the National Academy of Sciences of the United States of America 110 (37): 15073-15078. 10 September 2013

Neurokinin3 receptor as a target to predict and improve learning and memory in the aged organism.
de Souza Silva, M.A. and Lenz, B. and Rotter, A. and Biermann, T. and Peters, O. and Ramirez, A. and Jessen, F. and Maier, W. and Huell, M. and Schroeder, J. and Froelich, L. and Teipel, S. and Gruber, O. and Kornhuber, J. and Huston, J.P. and Mueller, C.P. and Schaeble, S.
Proceedings of the National Academy of Sciences of the United States of America 110 (37): 15097-15102. 10 September 2013

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma.
Pfeifer, M. and Grau, M. and Lenze, D. and Wenzel, S.S. and Wolf, A. and Wollert-Wulf, B. and Dietze, K. and Nogai, H. and Storek, B. and Madle, H. and Dörken, B. and Janz, M. and Dirnhofer, S. and Lenz, P. and Hummel, M. and Tzankov, A. and Lenz, G.
Proceedings of the National Academy of Sciences of the United States of America 110 (30): 12420-12425. 23 July 2013

Interfering with Gal-1-mediated angiogenesis contributes to the pathogenesis of preeclampsia.
Freitag, N. and Tirado-González, I. and Barrientos, G. and Herse, F. and Thijssen, V.L.J.L. and Weedon-Fekjær, S.M. and Schulz, H. and Wallukat, G. and Klapp, B.F. and Nevers, T. and Sharma, S. and Staff, A.C. and Dechend, R. and Blois, S.M.
Proceedings of the National Academy of Sciences of the United States of America 110 (28): 11451-11456. 9 July 2013

Histone deacetylase 10 promotes autophagy-mediated cell survival.
Oehme, I. and Linke, J.P. and Böck, B.C. and Milde, T. and Lodrini, M. and Hartenstein, B. and Wiegand, I. and Eckert, C. and Roth, W. and Kool, M. and Kaden, S. and Gröne, H.J. and Schulte, J.H. and Lindner, S. and Hamacher-Brady, A. and Brady, N.R. and Deubzer, H.E. and Witt, O.
Proceedings of the National Academy of Sciences of the United States of America 110 (28): E2592-E2601. 9 July 2013

Recruitment of oriens-lacunosum-moleculare interneurons during hippocampal ripples.
Pangalos, M. and Donoso, J.R. and Winterer, J. and Zivkovic, A.R. and Kempter, R. and Maier, N. and Schmitz, D.
Proceedings of the National Academy of Sciences of the United States of America 110 (11): 4398-4403. 12 March 2013

Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel.
Jin, L. and Feng, T. and Shih, H.P. and Zerda, R. and Luo, A. and Hsu, J. and Mahdavi, A. and Sander, M. and Tirrell, D.A. and Riggs, A.D. and Ku, H.T.
Proceedings of the National Academy of Sciences of the United States of America 110 (10): 3907-12. 5 March 2013

Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides.
Wefers, B. and Meyer, M. and Ortiz, O. and Hrabé de Angelis, M. and Hansen, J. and Wurst, W. and Kühn, R.
Proceedings of the National Academy of Sciences of the United States of America 110 (10): 3782-3787. 5 March 2013

Compromised fidelity of endocytic synaptic vesicle protein sorting in the absence of stonin 2.
Kononenko, N.L. and Diril, M.K. and Puchkov, D. and Kintscher, M. and Koo, S.J. and Pfuhl, G. and Winter, Y. and Wienisch, M. and Klingauf, J. and Breustedt, J. and Schmitz, D. and Maritzen, T. and Haucke, V.
Proceedings of the National Academy of Sciences of the United States of America 110 (6): E526-E535. 5 February 2013

Fas expression by tumor stroma is required for cancer eradication.
Listopad, J.J. and Kammertoens, T. and Anders, K. and Silkenstedt, B. and Willimsky, G. and Schmidt, K. and Kuehl, A.A. and Loddenkemper, C. and Blankenstein, T.
Proceedings of the National Academy of Sciences of the United States of America 110 (6): 2276-2281. 5 February 2013

Borna disease virus-induced neuronal degeneration dependent on host genetic background and prevented by soluble factors.
Wu, Y.J. and Schulz, H. and Lin, C.C. and Saar, K. and Patone, G. and Fischer, H. and Hübner, N. and Heimrich, B. and Schwemmle, M.
Proceedings of the National Academy of Sciences of the United States of America 110 (5): 1899-1904. 29 January 2013

Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.
Echalier, A. and Pan, Y. and Birol, M. and Tavernier, N. and Pintard, L. and Hoh, F. and Ebel, C. and Galophe, N. and Claret, F.X. and Dumas, C.
Proceedings of the National Academy of Sciences of the United States of America 110 (4): 1273-1278. 22 January 2013

Complexity of chromatin folding is captured by the strings and binders switch model.
Barbieri, M. and Chotalia, M. and Fraser, J. and Lavitas, L.M. and Dostie, J. and Pombo, A. and Nicodemi, M.
Proceedings of the National Academy of Sciences of the United States of America 109 (40): 16173-16178. 2 October 2012

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells.
Vaeth, M. and Schliesser, U. and Mueller, G. and Reissig, S. and Satoh, K. and Tuettenberg, A. and Jonuleit, H. and Waisman, A. and Mueller, M.R. and Serfling, E. and Sawitzki, B.S. and Berberich-Siebelt, F.
Proceedings of the National Academy of Sciences of the United States of America 109 (40): 16258-16263. 2 October 2012

Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.
Greulich, H. and Kaplan, B. and Mertins, P. and Chen, T.H. and Tanaka, K.E. and Yun, C.H. and Zhang, X. and Lee, S.H. and Cho, J. and Ambrogio, L. and Liao, R. and Imielinski, M. and Banerji, S. and Berger, A.H. and Lawrence, M.S. and Zhang, J. and Pho, N.H. and Walker, S.R. and Winckler, W. and Getz, G. and Frank, D. and Hahn, W.C. and Eck, M.J. and Mani, D.R. and Jaffe, J.D. and Carr, S.A. and Wong, K.K. and Meyerson, M.
Proceedings of the National Academy of Sciences of the United States of America 109 (36): 14476-14481. 4 September 2012

Deletion of claudin-10 (Cldn10) in the thick ascending limb impairs paracellular sodium permeability and leads to hypermagnesemia and nephrocalcinosis.
Breiderhoff, T. and Himmerkus, N. and Stuiver, M. and Mutig, K. and Will, C. and Meij, I.C. and Bachmann, S. and Bleich, M. and Willnow, T.E. and Mueller, D.
Proceedings of the National Academy of Sciences of the United States of America 109 (35): 14241-14246. 28 August 2012

Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior.
Warner-Schmidt, J.L. and Schmidt, E.F. and Marshall, J.J. and Rubin, A.J. and Arango-Lievano, M. and Kaplitt, M.G. and Ibanez-Tallon, I. and Heintz, N. and Greengard, P.
Proceedings of the National Academy of Sciences of the United States of America 109 (28): 11360-11365. 10 July 2012

Wnt/beta-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.
Klaus, A. and Mueller, M. and Schulz, H. and Saga, Y. and Martin, J.F. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 109 (27): 10921-10926. 3 July 2012

Modeling disease mutations by gene targeting in one-cell mouse embryos.
Meyer, M. and Ortiz, O. and Hrabe de Angelis, M. and Wurst, W. and Kuehn, R.
Proceedings of the National Academy of Sciences of the United States of America 109 (24): 9354-9359. 12 June 2012

Amorfrutins are potent antidiabetic dietary natural products.
Weidner, C. and de Groot, J.C. and Prasad, A. and Freiwald, A. and Quedenau, C. and Kliem, M. and Witzke, A. and Kodelja, V. and Han, C.T. and Giegold, S. and Baumann, M. and Klebl, B. and Siems, K. and Müller-Kuhrt, L. and Schürmann, A. and Schüler, R. and Pfeiffer, A.F.H. and Schroeder, F.C. and Büssow, K. and Sauer, S.
Proceedings of the National Academy of Sciences of the United States of America 109 (19): 7257-7262. 8 May 2012

The protein expression landscape of the Arabidopsis root.
Petricka, J.J. and Schauer, M.A. and Megraw, M. and Breakfield, N.W. and Thompson, J.W. and Georgiev, S. and Soderblom, E.J. and Ohler, U. and Moseley, M.A. and Grossniklaus, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 109 (18): 6811-6818. 1 May 2012

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages.
Schroder, K. and Irvine, K.M. and Taylor, M.S. and Bokil, N.J. and Le Cao, K.A. and Masterman, K.A. and Labzin, L.I. and Semple, C.A. and Kapetanovic, R. and Fairbairn, L. and Akalin, A. and Faulkner, G.J. and Baillie, J.K. and Gongora, M. and Daub, C.O. and Kawaji, H. and McLachlan, G.J. and Goldman, N. and Grimmond, S.M. and Carninci, P. and Suzuki, H. and Hayashizaki, Y. and Lenhard, B. and Hume, D.A. and Sweet, M.J.
Proceedings of the National Academy of Sciences of the United States of America 109 (16): E944-E953. 17 April 2012

Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter.
Chua, J.J.E. and Butkevich, E. and Worseck, J.M. and Kittelmann, M. and Gronborg, M. and Behrmann, E. and Stelzl, U. and Pavlos, N.J. and Lalowski, M.M. and Eimer, S. and Wanker, E.E. and Klopfenstein, D.R. and Jahn, R.
Proceedings of the National Academy of Sciences of the United States of America 109 (15): 5862-5867. 10 April 2012

Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB.
Voutilainen, M. and Lindfors, P.H. and Lefebvre, S. and Ahtiainen, L. and Fliniaux, I. and Rysti, E. and Murtoniemi, M. and Schneider, P. and Schmidt-Ullrich, R. and Mikkola, M.L.
Proceedings of the National Academy of Sciences of the United States of America 109 (15): 5744-5749. 10 April 2012

Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways.
D'Autreaux, F. and Coppola, E. and Hirsch, M.R. and Birchmeier, C. and Brunet, J.F.
Proceedings of the National Academy of Sciences of the United States of America 108 (50): 20018-20023. 13 December 2011

Interaction of complexes I, III, and IV within the bovine respirasome by single particle cryoelectron tomography.
Dudkina, N.V. and Kudryashev, M. and Stahlberg, H. and Boekema, E.J.
Proceedings of the National Academy of Sciences of the United States of America 108 (37): 15196-15200. 13 September 2011

Cellular correlate of assembly formation in oscillating hippocampal networks in vitro.
Baehner, F. and Weiss, E.K. and Birke, G. and Maier, N. and Schmitz, D. and Rudolph, U. and Frotscher, M. and Traub, R.D. and Both, M. and Draguhn, A.
Proceedings of the National Academy of Sciences of the United States of America 108 (35): E607-E616. 30 August 2011

Malt1-dependent RelB cleavage promotes canonical NF-κB activation in lymphocytes and lymphoma cell lines.
Hailfinger, S. and Nogai, H. and Pelzer, C. and Jaworski, M. and Cabalzar, K. and Charton, J.E. and Guzzardi, M. and Decaillet, C. and Grau, M. and Doerken, B. and Lenz, P. and Lenz, G. and Thome, M.
Proceedings of the National Academy of Sciences of the United States of America 108 (35): 14596-14601. 30 August 2011

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses.
Koo, S.J. and Markovic, S. and Puchkov, D. and Mahrenholz, C.C. and Beceren-Braun, F. and Maritzen, T. and Dernedde, J. and Volkmer, R. and Oschkinat, H. and Haucke, V.
Proceedings of the National Academy of Sciences of the United States of America 108 (33): 13540-13545. 16 August 2011

Cholinergic chemosensory cells in the trachea regulate breathing.
Krasteva, G. and Canning, B.J. and Hartmann, P. and Veres, T.Z. and Papadakis, T. and Muehlfeld, C. and Schliecker, K. and Tallini, Y.N. and Braun, A. and Hackstein, H. and Baal, N. and Weihe, E. and Schuetz, B. and Kotlikoff, M. and Ibanez-Tallon, I. and Kummer, W.
Proceedings of the National Academy of Sciences of the United States of America 108 (23): 9478-9483. 7 June 2011

Critical role of PI3K signaling for NF-κB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells.
Kloo, B. and Nagel, D. and Pfeifer, M. and Grau, M. and Duewel, M. and Vincendeau, M. and Doerken, B. and Lenz, P. and Lenz, G. and Krappmann, D.
Proceedings of the National Academy of Sciences of the United States of America 108 (1): 272-277. 4 January 2011

Derivation of Ca2+ signals from puff properties reveals that pathway function is robust against cell variability but sensitive for control.
Thurley, K. and Falcke, M.
Proceedings of the National Academy of Sciences of the United States of America 108 (1): 427-432. 4 January 2011

Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Guenther, S. and Schlundt, A. and Sticht, J. and Roske, Y. and Heinemann, U. and Wiesmueller, K.H. and Jung, G. and Falk, K. and Roetzschke, O. and Freund, C.
Proceedings of the National Academy of Sciences of the United States of America 107 (51): 22219-22224. 21 December 2010

Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2).
Schwefel, D. and Froehlich, C. and Eichhorst, J. and Wiesner, B. and Behlke, J. and Aravind, L. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 107 (47): 20299-20304. 23 November 2010

A synthetic-natural hybrid oscillator in human cells.
Toettcher, J.E. and Mock, C. and Batchelor, E. and Loewer, A. and Lahav, G.
Proceedings of the National Academy of Sciences of the United States of America 107 (39): 17047-17052. 28 September 2010

Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers.
Zhang, G. and Hoersch, S. and Amsterdam, A. and Whittaker, C.A. and Lees, J.A. and Hopkins, N.
Proceedings of the National Academy of Sciences of the United States of America 107 (39): 16940-16945. 28 September 2010

Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases.
Meyer, M. and de Angelis, M.H. and Wurst, W. and Kühn, R.
Proceedings of the National Academy of Sciences of the United States of America 107 (34): 15022-15026. 24 August 2010

The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus.
Tzingounis, A.V. and Heidenreich, M. and Kharkovets, T. and Spitzmaul, G. and Jensen, H.S. and Nicoll, R.A. and Jentsch, T.J.
Proceedings of the National Academy of Sciences of the United States of America 107 (22): 10232-10237. 1 June 2010

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity.
Bieschke, J. and Russ, J. and Friedrich, R.P. and Ehrnhoefer, D.E. and Wobst, H. and Neugebauer, K. and Wanker, E.E.
Proceedings of the National Academy of Sciences of the United States of America 107 (17): 7710-7715. 27 April 2010

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation.
Haurie, V. and Durrieu-Gaillard, S. and Dumay-Odelot, H. and Da Silva, D. and Rey, C. and Prochazkova, M. and Roeder, R.G. and Besser, D. and Teichmann, M.
Proceedings of the National Academy of Sciences of the United States of America 107 (9): 4176-4181. 2 March 2010

Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion.
Zhang, J. and Piontek, J. and Wolburg, H. and Piehl, C. and Liss, M. and Otten, C. and Christ, A. and Willnow, T.E. and Blasig, I.E. and Abdelilah-Seyfried, S.
Proceedings of the National Academy of Sciences of the United States of America 107 (4): 1425-1430. 26 January 2010

NCLX is an essential component of mitochondrial Na+/Ca2+ exchange.
Palty, R. and Silverman, W.F. and Hershfinkel, M. and Caporale, T. and Sensi, S.L. and Parnis, J. and Nolte, C. and Fishman, D. and Shoshan-Barmatz, V. and Herrmann, S. and Khananshvili, D. and Sekler, I.
Proceedings of the National Academy of Sciences of the United States of America 107 (1): 436-441. 5 January 2010

CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens.
Nitta, T. and Nitta, S. and Lei, Y. and Lipp, M. and Takahama, Y.
Proceedings of the National Academy of Sciences of the United States of America 106 (40): 17129-17133. 6 October 2009

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S. and Wende, H. and Paul, F.E. and Cheret, C. and Garratt, A.N. and Zurborg, S. and Feinberg, K. and Besser, D. and Schulz, H. and Peles, E. and Selbach, M. and Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons.
Schmidt, H. and Stonkute, A. and Juettner, R. and Koesling, D. and Friebe, A. and Rathjen, F.G.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16847-16852. 29 September 2009

Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system.
Stegbauer, J. and Lee, D.H. and Seubert, S. and Ellrichmann, G. and Manzel, A. and Kvakan, H. and Mueller, D.N. and Gaupp, S. and Rump, L.C. and Gold, R. and Linker, R.A.
Proceedings of the National Academy of Sciences of the United States of America 106 (35): 14942-14947. 1 September 2009

Single-molecule force spectroscopy distinguishes target binding modes of calmodulin.
Junker, J.P. and Rief, M.
Proceedings of the National Academy of Sciences of the United States of America 106 (34): 14361-14366. 25 August 2009

Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis.
Blume, M. and Rodriguez-Contreras, D. and Landfear, S. and Fleige, T. and Soldati-Favre, D. and Lucius, R. and Gupta, N.
Proceedings of the National Academy of Sciences of the United States of America 106 (31): 12998-13003. 4 August 2009

Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion.
Markovic, D.S. and Vinnakota, K. and Chirasani, S. and Synowitz, M. and Raguet, H. and Stock, K. and Sliwa, M. and Lehmann, S. and Kaelin, R. and van Rooijen, N. and Holmbeck, K. and Heppner, F.L. and Kiwit, J. and Matyash, V. and Lehnardt, S. and Kaminska, B. and Glass, R. and Kettenmann, H.
Proceedings of the National Academy of Sciences of the United States of America 106 (30): 12530-12535. 28 July 2009

High-resolution profiling and discovery of planarian small RNAs.
Friedlaender, M.R. and Adamidi, C. and Han, T. and Lebedeva, S. and Isenbarger, T.A. and Hirst, M. and Marra, M. and Nusbaum, C. and Lee, W.L. and Jenkin, J.C. and Alvarado, A.S. and Kim, J.K. and Rajewsky, N.
Proceedings of the National Academy of Sciences of the United States of America 106 (28): 11546-11551. 14 July 2009

Growth retardation and altered autonomic control in mice lacking brain serotonin.
Alenina, N. and Kikic, D. and Todiras, M. and Mosienko, V. and Qadri, F. and Plehm, R. and Boye, P. and Vilianovitch, L. and Sohr, R. and Tenner, K. and Hoertnagl, H. and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 106 (25): 10332-10337. 23 June 2009

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function.
Wang, S. and Jensen, J.N. and Seymour, P.A. and Hsu, W. and Dor, Y. and Sander, M. and Magnuson, M.A. and Serup, P. and Gu, G.
Proceedings of the National Academy of Sciences of the United States of America 106 (24): 9715-20. 16 June 2009

The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse.
Vasyutina, E. and Martarelli, B. and Brakebusch, C. and Wende, H. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (22): 8935-8940. 2 June 2009

Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma.
Mathas, S. and Kreher, S. and Meaburn, K.J. and Joehrens, K. and Lamprecht, B. and Assaf, C. and Sterry, W. and Kadin, M.E. and Daibata, M. and Joos, S. and Hummel, M. and Stein, H. and Janz, M. and Anagnostopoulos, I. and Schrock, E. and Misteli, T. and Doerken, B.
Proceedings of the National Academy of Sciences of the United States of America 106 (14): 5831-5836. 7 April 2009

miR-375 maintains normal pancreatic α- and β-cell mass.
Poy, M.N. and Hausser, J. and Trajkovski, M. and Braun, M. and Collins, S. and Rorsman, P. and Zavolan, M. and Stoffel, M.
Proceedings of the National Academy of Sciences of the United States of America 106 (14): 5813-5818. 7 April 2009

A role for LYNX2 in anxiety-related behavior.
Tekinay, A.B. and Nong, Y. and Miwa, J.M. and Lieberam, I. and Ibanez-Tallon, I. and Greengard, P. and Heintz, N.
Proceedings of the National Academy of Sciences of the United States of America 106 (11): 4477-4482. 17 March 2009

Quantifying environmental adaptation of metabolic pathways in metagenomics.
Gianoulis, T.A. and Raes, J. and Patel, P.V. and Bjornson, R. and Korbel, J.O. and Letunic, I. and Yamada, T. and Paccanaro, A. and Jensen, L.J. and Snyder, M. and Bork, P. and Gerstein, M.B.
Proceedings of the National Academy of Sciences of the United States of America 106 (5): 1374-1379. 3 February 2009

Distinct mechanisms act in concert to mediate cell cycle arrest.
Toettcher, J.E. and Loewer, A. and Ostheimer, G.J. and Yaffe, M.B. and Tidor, B. and Lahav, G.
Proceedings of the National Academy of Sciences of the United States of America 106 (3): 785-790. 20 January 2009

DGCR8-dependent microRNA biogenesis is essential for skin development.
Yi, R. and Pasolli, H.A. and Landthaler, M. and Hafner, M. and Ojo, T. and Sheridan, R. and Sander, C. and O'Carroll, D. and Stoffel, M. and Tuschl, T. and Fuchs, E.
Proceedings of the National Academy of Sciences of the United States of America 106 (2): 498-502. 13 January 2009

Identification of gene 3' ends by automated EST cluster analysis.
Muro, E.M. and Herrington, R. and Janmohamed, S. and Frelin, C. and Andrade-Navarro, M.A. and Iscove, N.N.
Proceedings of the National Academy of Sciences of the United States of America 105 (51): 20286-20290. 23 December 2008

β-catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation.
Zelarayan, L.C. and Noack, C. and Sekkali, B. and Kmecova, J. and Gehrke, C. and Renger, A. and Zafiriou, M.P. and van der Nagel, R. and Dietz, R. and de Windt, L.J. and Balligand, J.L. and Bergmann, M.W.
Proceedings of the National Academy of Sciences of the United States of America 105 (50): 19762-19767. 16 December 2008

ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear.
Anselmi, F. and Hernandez, V.H. and Crispino, G. and Seydel, A. and Ortolano, S. and Roper, S.D. and Kessaris, N. and Richardson, W. and Rickheit, G. and Filippov, M.A. and Monyer, H. and Mammano, F.
Proceedings of the National Academy of Sciences of the United States of America 105 (48): 18770-18775. 2 December 2008

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas.
Kruschinski, A. and Moosmann, A. and Poschke, I. and Norell, H. and Chmielewski, M. and Seliger, B. and Kiessling, R. and Blankenstein, T. and Abken, H. and Charo, J.
Proceedings of the National Academy of Sciences of the United States of America 105 (45): 17481-17486. 11 November 2008

Evolution of the phospho-tyrosine signaling machinery in premetazoan lineages.
Pincus, D. and Letunic, I. and Bork, P. and Lim, W.A.
Proceedings of the National Academy of Sciences of the United States of America 105 (28): 9680-9684. 15 July 2008

Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking.
Hellmuth, K. and Grosskopf, S. and Lum, C.T. and Wuertele, M. and Roeder, N. and von Kries, J.P. and Rosario, M. and Rademann, J. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 105 (20): 7275-7280. 20 May 2008

Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis.
Martin, M. and Potente, M. and Janssens, V. and Vertommen, D. and Twizere, J.C. and Rider, M.H. and Goris, J. and Dimmeler, S. and Kettmann, R. and Dequiedt, F.
Proceedings of the National Academy of Sciences of the United States of America 105 (12): 4727-4732. 25 March 2008

Transposition of a reconstructed Harbinger element in human cells and functional homology with two transposon-derived cellular genes.
Sinzelle, L. and Kapitonov, V.V. and Grzela, D.P. and Jursch, T. and Jurka, J. and Izsvak, Z. and Ivics, Z.
Proceedings of the National Academy of Sciences of the United States of America 105 (12): 4715-4720. 25 March 2008

Temporal compression mediated by short-term synaptic plasticity.
Leibold, C. and Gundlfinger, A. and Schmidt, R. and Thurley, K. and Schmitz, D. and Kempter, R.
Proceedings of the National Academy of Sciences of the United States of America 105 (11): 4417-4422. 18 March 2008

Requirement of protein kinase D1 for pathological cardiac remodeling.
Fielitz, J. and Kim, M.S. and Shelton, J.M. and Qi, X. and Hill, J.A. and Richardson, J.A. and Bassel-Duby, R. and Olson, E.N.
Proceedings of the National Academy of Sciences of the United States of America 105 (8): 3059-3063. 26 February 2008

A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer.
Kieback, E. and Charo, J. and Sommermeyer, D. and Blankenstein, T. and Uckert, W.
Proceedings of the National Academy of Sciences of the United States of America 105 (2): 623-628. 15 January 2008

Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis.
Klaus, A. and Saga, Y. and Taketo, M.M. and Tzahor, E. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 104 (47): 18531-18536. 20 November 2007

Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
Schaeper, U. and Vogel, R. and Chmielowiec, J. and Huelsken, J. and Rosario, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 104 (39): 15376-15381. 25 September 2007

Proteasomal selection of multiprotein complexes recruited by LIM homeodomain transcription factors.
Guengoer, C. and Taniguchi-Ishigaki, N. and Ma, H. and Drung, A. and Tursun, B. and Ostendorff, H.P. and Bossenz, M. and Becker, C.G. and Becker, T. and Bach, I.
Proceedings of the National Academy of Sciences of the United States of America 104 (38): 15000-15005. 18 September 2007

Quantitative assessment of protein function prediction from metagenomics shotgun sequences.
Harrington, E.D. and Singh, A.H. and Doerks, T. and Letunic, I. and von Mering, C. and Jensen, L.J. and Raes, J. and Bork, P.
Proceedings of the National Academy of Sciences of the United States of America 104 (35): 13913-13918. 28 August 2007

TRPA1 mediates formalin-induced pain.
McNamara, C.R. and Mandel-Brehm, J. and Bautista, D.M. and Siemens, J. and Deranian, K.L. and Zhao, M. and Hayward, N.J. and Chong, J.A. and Julius, D. and Moran, M.M. and Fanger, C.M.
Proceedings of the National Academy of Sciences of the United States of America 104 (33): 13525-13530. 14 August 2007

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Trevisani, M. and Siemens, J. and Materazzi, S. and Bautista, D.M. and Nassini, R. and Campi, B. and Imamachi, N. and Andre, E. and Patacchini, R. and Cottrell, G.S. and Gatti, R. and Basbaum, A.I. and Bunnett, N.W. and Julius, D. and Geppetti, P.
Proceedings of the National Academy of Sciences of the United States of America 104 (33): 13519-13524. 14 August 2007

Cellular cofactors affecting hepatitis C virus infection and replication.
Randall, G. and Panis, M. and Cooper, J.D. and Tellinghuisen, T.L. and Sukhodolets, K.E. and Pfeffer, S. and Landthaler, M. and Landgraf, P. and Kan, S. and Lindenbach, B.D. and Chien, M. and Weir, D.B. and Russo, J.J. and Ju, J. and Brownstein, M.J. and Sheridan, R. and Sander, C. and Zavolan, M. and Tuschl, T. and Rice, C.M.
Proceedings of the National Academy of Sciences of the United States of America 104 (31): 12884-12889. 31 July 2007

Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance.
Piaggio, E. and Mars, L.T. and Cassan, C. and Cabarrocas, J. and Hofstätter, M. and Desbois, S. and Bergereau, E. and Roetzschke, O. and Falk, K. and Liblau, R.S.
Proceedings of the National Academy of Sciences of the United States of America 104 (22): 9393-9398. 29 May 2007

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.
Nielsen, R. and Courtoy, P.J. and Jacobsen, C. and Dom, G. and Lima, W.R. and Jadot, M. and Willnow, T.E. and Devuyst, O. and Christensen, E.I.
Proceedings of the National Academy of Sciences of the United States of America 104 (13): 5407-5412. 27 March 2007

Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction.
Fielitz, J. and van Rooij, E. and Spencer, J.A. and Shelton, J.M. and Latif, S. and van der Nagel, R. and Bezprozvannaya, S. and de Windt, L. and Richardson, J.A. and Bassel-Duby, R. and Olson, E.N.
Proceedings of the National Academy of Sciences of the United States of America 104 (11): 4377-4382. 13 March 2007

RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells.
Vasyutina, E. and Lenhard, D.C. and Wende, H. and Erdmann, B. and Epstein, J.A. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 104 (11): 4443-4448. 13 March 2007

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy.
Radke, M.H. and Peng, J. and Wu, Y. and McNabb, M. and Nelson, O.L. and Granzier, H. and Gotthardt, M.
Proceedings of the National Academy of Sciences of the United States of America 104 (9): 3444-3449. 27 February 2007

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.
Suchting, S. and Freitas, C. and le Noble, F. and Benedito, R. and Breant, C. and Duarte, A. and Eichmann, A.
Proceedings of the National Academy of Sciences of the United States of America 104 (9): 3225-3230. 27 February 2007

SOX9 is required for maintenance of the pancreatic progenitor cell pool.
Seymour, P.A. and Freude, K.K. and Tran, M.N. and Mayes, E.E. and Jensen, J. and Kist, R. and Scherer, G. and Sander, M.
Proceedings of the National Academy of Sciences of the United States of America 104 (6): 1865-70. 6 February 2007

Continuous tooth generation in mouse is induced by activated epithelial Wnt/β-catenin signaling.
Jaervinen, E. and Salazar-Ciudad, I. and Birchmeier, W. and Taketo, M.M. and Jernvall, J. and Thesleff, I.
Proceedings of the National Academy of Sciences of the United States of America 103 (49): 18627-18632. 5 December 2006

Diversin regulates heart formation and gastrulation movements in development.
Moeller, H. and Jenny, A. and Schaeffer, H.J. and Schwarz-Romond, T. and Mlodzik, M. and Hammerschmidt, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 103 (43): 15900-15905. 24 October 2006

Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis.
Sakai, N. and Wada, T. and Yokoyama, H. and Lipp, M. and Ueha, S. and Matsushima, K. and Kaneko, S.
Proceedings of the National Academy of Sciences of the United States of America 103 (38): 14098-14103. 19 September 2006

Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6.
Poet, M. and Kornak, U. and Schweizer, M. and Zdebik, A.A. and Scheel, O. and Hoelter, S. and Wurst, W. and Schmitt, A. and Fuhrmann, J.C. and Planells-Cases, R. and Mole, S.E. and Huebner, C.A. and Jentsch, T.J.
Proceedings of the National Academy of Sciences of the United States of America 103 (37): 13854-13859. 12 September 2006

Unique self-palmitoylation activity of the transport protein particle component Bet3: A mechanism required for protein stability.
Kuemmel, D. and Heinemann, U. and Veit, M.
Proceedings of the National Academy of Sciences of the United States of America 103 (34): 12701-12706. 22 August 2006

Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer.
Hadjihannas, M.V. and Brueckner, M. and Jerchow, B. and Birchmeier, W. and Dietmaier, W. and Behrens, J.
Proceedings of the National Academy of Sciences of the United States of America 103 (28): 10747-10752. 11 July 2006

Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destruction.
Geibel, J. and Sritharan, K. and Geibel, R. and Geibel, P. and Persing, J.S. and Seeger, A. and Roepke, T.K. and Deichstetter, M. and Prinz, C. and Cheng, S.X. and Martin, D. and Hebert, S.C.
Proceedings of the National Academy of Sciences of the United States of America 103 (25): 9390-9397. 20 June 2006

Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.
Wagner, K. and Zhang, P. and Rosenbauer, F. and Drescher, B. and Kobayashi, S. and Radomska, H.S. and Kutok, J.L. and Gilliland, D.G. and Krauter, J. and Tenen, D.G.
Proceedings of the National Academy of Sciences of the United States of America 103 (16): 6338-6343. 18 April 2006

Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots.
Lee, J.Y. and Colinas, J. and Wang, J.Y. and Mace, D. and Ohler, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 103 (15): 6055-6060. 11 April 2006

A structural role for ATP in the formation and stability of the human origin recognition complex.
Ranjan, A. and Gossen, M.
Proceedings of the National Academy of Sciences of the United States of America 103 (13): 4864-4869. 28 March 2006

Cardiac hypertrophy in transgenic rats expressing a dominant-negative mutant of the natriuretic peptide receptor B.
Langenickel, T.H. and Buttgereit, J. and Pagel-Langenickel, I. and Lindner, M. and Monti, J. and Beuerlein, K. and Al-Saadi, N. and Plehm, R. and Popova, E. and Tank, J. and Dietz, R. and Willenbrock, R. and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 103 (12): 4735-4740. 21 March 2006

Sleeping Beauty transposase modulates cell-cycle progression through interaction with Miz-1.
Walisko, O. and Izsvak, Z. and Szabo, K. and Kaufman, C.D. and Herold, S. and Ivics, Z.
Proceedings of the National Academy of Sciences of the United States of America 103 (11): 4062-4067. 14 March 2006

Running in pregnancy transiently increases postnatal hippocampal neurogenesis in the offspring.
Bick-Sander, A. and Steiner, B. and Wolf, S.A. and Babu, H. and Kempermann, G.
Proceedings of the National Academy of Sciences of the United States of America 103 (10): 3852-3857. 7 March 2006

Cell type specific signatures of microRNAs on target mRNA expression.
Sood, P. and Krek, A. and Zavolan, M. and Macino, G. and Rajewsky, N.
Proceedings of the National Academy of Sciences of the United States of America 103 (8): 2746-2751. 21 February 2006

13C isotopologue perturbation studies of Listeria monocytogenes carbon metabolism and its modulation by the virulence regulator PrfA.
Eisenreich, W. and Slaghuis, J. and Laupitz, R. and Bussemer, J. and Stritzker, J. and Schwarz, C. and Schwarz, R. and Dandekar, T. and Goebel, W. and Bacher, A.
Proceedings of the National Academy of Sciences of the United States of America 103 (7): 2040-2045. 14 February 2006

Natural variation and genetic covariance in adult hippocampal neurogenesis.
Kempermann, G. and Chesler, E.J. and Lu, L. and Williams, R.W. and Gage, F.H.
Proceedings of the National Academy of Sciences of the United States of America 103 (3): 780-785. 17 January 2006

Spatial regulation of microRNA gene expression in the Drosophila embryo.
Biemar, F. and Zinzen, R.P. and Ronshaugen, M. and Sementchenko, V. and Manak, J.R. and Levine, M.S.
Proceedings of the National Academy of Sciences of the United States of America 102 (44): 15907-15911. 1 November 2005

Auditory orientation in crickets: pattern recognition controls reactive steering.
Poulet, J.F.A. and Hedwig, B.
Proceedings of the National Academy of Sciences of the United States of America 102 (43): 15665-15669. 25 October 2005

Viral targeting of the interferon-beta-inducing Traf family member-associated NF-kappaB activator (TANK)-binding kinase-1.
Unterstab, G. and Ludwig, S. and Anton, A. and Planz, O. and Dauber, B. and Krappmann, D. and Heins, G. and Ehrhardt, C. and Wolff, T.
Proceedings of the National Academy of Sciences of the United States of America 102 (38): 13640-13645. 9 September 2005

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Andersen, O.M. and Reiche, J. and Schmidt, V. and Gotthardt, M. and Spoelgen, R. and Behlke, J. and von Arnim, C.A.F. and Breiderhoff, T. and Jansen, P. and Wu, X. and Bales, K.R. and Cappai, R. and Masters, C.L. and Gliemann, J. and Mufson, E.J. and Hyman, B.T. and Paul, S.M. and Nykjaer, A. and Willnow, T.E.
Proceedings of the National Academy of Sciences of the United States of America 102 (38): 13461-13466. 7 September 2005

The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex.
Otto, H. and Conz, C. and Maier, P. and Woelfle, T. and Suzuki, C.K. and Jenoe, P. and Ruecknagel, P. and Stahl, J. and Rospert, S.
Proceedings of the National Academy of Sciences of the United States of America 102 (29): 10064-10069. 19 July 2005

Recruitment of DNA methyltransferase I to DNA repair sites.
Mortusewicz, O. and Schermelleh, L. and Walter, J. and Cardoso, M.C. and Leonhardt, H.
Proceedings of the National Academy of Sciences of the United States of America 102 (25): 8905-8909. 21 June 2005

A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse.
Zheng, Z. and Schmidt-Ott, K.M. and Chua, S. and Foster, K.A. and Frankel, R.Z. and Pavlidis, P. and Barasch, J. and D'Agati, V.D. and Gharavi, A.G.
Proceedings of the National Academy of Sciences of the United States of America 102 (7): 2502-2507. 15 February 2005

A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo.
Zhang, X. and Smith, D.L. and Meriin, A.B. and Engemann, S. and Russel, D.E. and Roark, M. and Washington, S.L. and Maxwell, M.M. and Marsh, J.L. and Thompson, L.M. and Wanker, E.E. and Young, A.B. and Housman, D.E. and Bates, G.P. and Sherman, M.Y. and Kazantsev, A.G.
Proceedings of the National Academy of Sciences of the United States of America 102 (3): 892-897. 18 January 2005

Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele.
Graveel, C. and Su, Y. and Koeman, J. and Wang, L.M. and Tessarollo, L. and Fiscella, M. and Birchmeier, C. and Swiatek, P. and Bronson, R. and Vande Woude, G.F.
Proceedings of the National Academy of Sciences of the United States of America 101 (49): 17198-17203. 7 December 2004

Loss of chondroitin 6-O-sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement.
Thiele, H. and Sakano, M. and Kitagawa, H. and Sugahara, K. and Rajab, A. and Hoehne, W. and Ritter, H. and Leschik, G. and Nuernberg, P. and Mundlos, S.
Proceedings of the National Academy of Sciences of the United States of America 101 (27): 10155-10160. 23 June 2004

A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway.
Bush, E. and Fielitz, J. and Melvin, L. and Martinez-Arnold, M. and McKinsey, T.A. and Plichta, R. and Olson, E.N.
Proceedings of the National Academy of Sciences of the United States of America 101 (9): 2870-2875. 2 March 2004

The MafA transcription factor appears to be responsible for tissue-specific expression of insulin.
Matsuoka, T. and Artner, I. and Henderson, E. and Means, A. and Sander, M. and Stein, R.
Proceedings of the National Academy of Sciences of the United States of America 101 (9): 2930-3. 2 March 2004

Met provides essential signals for liver regeneration.
Borowiak, M. and Garratt, A.N. and Wuestefeld, T. and Strehle, M. and Trautwein, C. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 101 (29): 10608-10613. 1 January 2004

Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses.
Moore, K.A. and Nicoll, R.A. and Schmitz, D.
Proceedings of the National Academy of Sciences of the United States of America 100 (24): 14397-14402. 25 November 2003

α1E-containing Ca2+ channels are involved in synaptic plasticity.
Breustedt, J. and Vogt, K.E. and Miller, R.J. and Nicoll, R.A. and Schmitz, D.
Proceedings of the National Academy of Sciences of the United States of America 100 (21): 12450-12455. 14 October 2003

Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2.
Lehmann, K. and Seemann, P. and Stricker, S. and Sammar, M. and Meyer, B. and Suering, K. and Majewski, F. and Tinschert, S. and Grzeschik, K.H. and Mueller, D. and Knaus, P. and Nuernberg, P. and Mundlos, S.
Proceedings of the National Academy of Sciences of the United States of America 100 (21): 12277-12282. 14 October 2003

Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.
Wolfrum, C. and Besser, D. and Luca, E. and Stoffel, M.
Proceedings of the National Academy of Sciences of the United States of America 100 (20): 11624-11629. 30 September 2003

Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas.
Santos, R.A.S. and e Silva, A.C.S. and Maric, C. and Silva, D.M.R. and Machado, R.P. and de Buhr, I. and Heringer-Walther, S. and Pinheiro, S.V.B. and Lopes, M.T. and Bader, M. and Mendes, E.P. and Lemos, V.S. and Campagnole-Santos, M.J. and Schultheiss, H.P. and Speth, R. and Walther, T.
Proceedings of the National Academy of Sciences of the United States of America 100 (14): 8258-8263. 8 July 2003

Preferential megalin-mediated transcytosis of low-hormonogenic thyroglobulin: A control mechanism for thyroid hormone release.
Lisi, S. and Pinchera, A. and McCluskey, R.T. and Willnow, T.E. and Refetoff, S. and Marcocci, C. and Vitti, P. and Menconi, F. and Grasso, L. and Luchetti, F. and Collins, A.B. and Marino, M.
Proceedings of the National Academy of Sciences of the United States of America 100 (25): 14858-14863. 1 January 2003

Genome evolution reveals biochemical networks and functional modules.
von Mering, C. and Zdobnov, E.M. and Tsoka, S. and Ciccarelli, F.D. and Pereira-Leal, J.B. and Ouzounis, C.A. and Bork, P.
Proceedings of the National Academy of Sciences of the United States of America 100 (26): 15428-15433. 1 January 2003

A pH-sensitive histidine residue as control element for ligand release from HLA-DR molecules.
Roetzschke, O. and Lau, J.M. and Hofstätter, M. and Falk, K. and Strominger, J.L.
Proceedings of the National Academy of Sciences of the United States of America 99 (26): 16946-16950. 24 December 2002

Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay.
Heiser, V. and Engemann, S. and Broecker, W. and Dunkel, I. and Boeddrich, A. and Waelter, S. and Nordhoff, E. and Lurz, R. and Schugardt, N. and Rautenberg, S. and Herhaus, C. and Barnickel, G. and Boettcher, H. and Lehrach, H. and Wanker, E.E.
Proceedings of the National Academy of Sciences of the United States of America 99 (Suppl 4): 16400-16406. 10 December 2002

The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions.
Siemens, J. and Kazmierczak, P. and Reynolds, A. and Sticker, M. and Littlewood-Evans, A. and Mueller, U.
Proceedings of the National Academy of Sciences of the United States of America 99 (23): 14946-14951. 12 November 2002

Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy.
Knauf, F. and Rogina, B. and Jiang, Z. and Aronson, P.S. and Helfand, S.L.
Proceedings of the National Academy of Sciences of the United States of America 99 : 14315-14319. 29 October 2002

The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract.
Schell, M.A. and Karmirantzou, M. and Snel, B. and Vilanova, D. and Berger, B. and Pessi, G. and Zwahlen, M.C. and Desiere, F. and Bork, P. and Delley, M. and Pridmore, R.D. and Arigoni, F.
Proceedings of the National Academy of Sciences of the United States of America 99 (22): 14422-14427. 29 October 2002

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Özcelik, C. and Erdmann, B. and Pilz, B. and Wettschureck, N. and Britsch, S. and Hübner, N. and Chien, K.R. and Birchmeier, C. and Garratt, A.N.
Proceedings of the National Academy of Sciences of the United States of America 99 (13): 8880-8885. 25 June 2002

Comparative genomic analysis in the region of a major Plasmodium-refractoriness locus of Anopheles gambiae.
Thomasova, D. and Ton, L.Q. and Copley, R.R. and Zdobnov, E.M. and Wang, X. and Hong, Y.S. and Sim, C. and Bork, P. and Kafatos, F.C. and Collins, F.H.
Proceedings of the National Academy of Sciences of the United States of America 99 : 8179-8184. 11 June 2002

Probabilistic clustering of sequences: inferring new bacterial regulons by comparative genomics.
van Nimwegen, E. and Zavolan, M. and Rajewsky, N. and Siggia, E.D.
Proceedings of the National Academy of Sciences of the United States of America 99 (11): 7323-7328. 28 May 2002

Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure.
Holtwick, R. and Gotthardt, M. and Skryabin, B. and Steinmetz, M. and Potthast, R. and Zetsche, B. and Hammer, R.E. and Herz, J. and Kuhn, M.
Proceedings of the National Academy of Sciences of the United States of America 99 : 7142-7147. 14 May 2002

The identification of functional modules from the genomic association of genes.
Snel, B. and Bork, P. and Huynen, M.A.
Proceedings of the National Academy of Sciences of the United States of America 99 : 5890-5895. 30 April 2002

Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid β-peptide of amyloid plaques.
Perutz, M.F. and Pope, B.J. and Owen, D. and Wanker, E.E. and Scherzinger, E.
Proceedings of the National Academy of Sciences of the United States of America 99 (8): 5596-5600. 16 April 2002

Evidence for a NOD2-independent susceptibility locus for inflammatory bowel disease on chromosome 16p.
Hampe, J. and Frenzel, H. and Mirza, M.M. and Croucher, P.J. and Cuthbert, A. and Mascheretti, S. and Huse, K. and Platzer, M. and Bridger, S. and Meyer, B. and Nuernberg, P. and Stokkers, P. and Krawczak, M. and Mathew, C.G. and Curran, M. and Schreiber, S.
Proceedings of the National Academy of Sciences of the United States of America 99 (1): 321-326. 8 January 2002

Bazooka and atypical protein kinase C are required to regulate oocyte differentiation in the Drosophila ovary.
Cox, D.N. and Seyfried, S.A. and Jan, L.Y. and Jan, Y.N.
Proceedings of the National Academy of Sciences of the United States of America 98 : 14475-14480. 4 December 2001

Vaccination, prevention, and treatment of experimental autoimmune neuritis (EAN) by an oligomerized T cell epitope.
Stienekemeier, M. and Falk, K. and Roetzschke, O. and Weishaupt, A. and Schneider, C. and Toyka, K.V. and Gold, R. and Strominger, J.L.
Proceedings of the National Academy of Sciences of the United States of America 98 (24): 13872-13877. 1 November 2001

Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channel.
Dedek, K. and Kunath, B. and Kananura, C. and Reuner, U. and Jentsch, T.J. and Steinlein, O.K.
Proceedings of the National Academy of Sciences of the United States of America 98 (21): 12272-12277. 9 October 2001

Presynaptic kainate receptors at hippocampal mossy fiber synapses.
Schmitz, D. and Mellor, J. and Frerking, M. and Nicoll, R.A.
Proceedings of the National Academy of Sciences of the United States of America 98 (20): 11003-11008. 25 September 2001

When genetic distance matters: measuring genetic differentiation at microsatellite loci in whole-genome scans of recent and incipient mosquito species.
Wang, R. and Zheng, L. and Toure, Y.T. and Dandekar, T. and Kafatos, F.C.
Proceedings of the National Academy of Sciences of the United States of America 98 (19): 10769-10774. 11 September 2001

The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia.
Fuchs, U. and Rehkamp, G. and Haas, O.A. and Slany, R. and Konig, M. and Bojesen, S. and Bohle, R.M. and Damm-Welk, C. and Ludwig, W.D. and Harbott, J. and Borkhardt, A.
Proceedings of the National Academy of Sciences of the United States of America 98 (15): 8756-8761. 17 July 2001

BDNF but not NT-4 is required for normal flexion reflex plasticity and function.
Heppenstall, P.A. and Lewin, G.R.
Proceedings of the National Academy of Sciences of the United States of America 98 (14): 8107-8112. 3 July 2001

Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia.
Kozyraki, R. and Fyfe, J. and Verroust, P.J. and Jacobsen, C. and Dautry-Varsat, A. and Gburek, J. and Willnow, T.E. and Christensen, E.I. and Moestrup, S.K.
Proceedings of the National Academy of Sciences of the United States of America 98 (22): 12491-12496. 1 January 2001

S100A1: A regulator of myocardial contractility.
Most, P. and Bernotat, J. and Ehlermann, P. and Pleger, S.T. and Reppel, M. and Boerries, M. and Niroomand, F. and Pieske, B. and Janssen, P.M.L. and Eschenhagen, T. and Karczewski, P. and Smith, G.L. and Koch, W.J.K. and Katus, H.A. and Remppis, A.
Proceedings of the National Academy of Sciences of the United States of America 98 (24): 13889-13894. 1 January 2001

Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D-3.
Nykjaer, A. and Fyfe, J.C. and Kozyraki, R. and Leheste, J.R. and Jacobsen, C. and Nielsen, M.S. and Verroust, P.J. and Aminoff, M. and de la Chapelle, A. and Moestrup, S.K. and Ray, R. and Gliemann, J. and Willnow, T.E. and Christensen, E.I.
Proceedings of the National Academy of Sciences of the United States of America 98 (24): 13895-13900. 1 January 2001

Paternal relatedness and age proximity regulate social relationships among adult female rhesus macaques.
Widdig, A. and Nuernberg, P. and Krawczak, M. and Streich, W.J. and Bercovitch, F.B.
Proceedings of the National Academy of Sciences of the United States of America 98 (24): 13769-13773. 1 January 2001

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils.
Muchowski, P.J. and Schaffar, G. and Sittler, A. and Wanker, E.E. and Hayer-Hartl, M.K. and Hartl, F.U.
Proceedings of the National Academy of Sciences of the United States of America 97 (14): 7841-7846. 5 July 2000

Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.
Nylandsted, J. and Rohde, M. and Brand, K. and Bastholm, L. and Elling, F. and Jaattela, M.
Proceedings of the National Academy of Sciences of the United States of America 97 (14): 7871-7876. 5 July 2000

Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors.
Pesquero, J.B. and Araujo, R.C. and Heppenstall, P.A. and Stucky, C.L. and Silva, J.A. and Walther, T. and Oliveira, S.M. and Pesquero, J.L. and Paiva, A.C.M. and Calixto, J.B. and Lewin, G.R. and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 97 (14): 8140-8145. 5 July 2000

Anopheles gambiae pilot gene discovery project: Identification of mosquito innate immunity genes from expressed sequence tags generated from immune-competent cell lines.
Dimopoulos, G. and Casavant, T.L. and Chang, S.R. and Scheetz, T. and Roberts, C. and Donohue, M. and Schultz, J. and Benes, V. and Bork, P. and Ansorge, W. and Soares, M.B. and Kafatos, F.C.
Proceedings of the National Academy of Sciences of the United States of America 97 (12): 6619-6624. 6 June 2000

Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy.
Heiser, V. and Scherzinger, E. and Boeddrich, A. and Nordhoff, E. and Lurz, R. and Schugardt, N. and Lehrach, H. and Wanker, E.E.
Proceedings of the National Academy of Sciences of the United States of America 97 (12): 6739-6744. 6 June 2000

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
Steffan, J.S. and Kazantsev, A. and Spasic-Boskovic, O. and Greenwald, M. and Zhu, Y.Z. and Gohler, H. and Wanker, E.E. and Bates, G.P. and Housman, D.E. and Thompson, L.M.
Proceedings of the National Academy of Sciences of the United States of America 97 : 6763-6768. 6 June 2000

KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway.
Kharkovets, T. and Hardelin, J.P. and Safieddine, S. and Schweizer, M. and El-Amraoui, A. and Petit, C. and Jentsch, T.J.
Proceedings of the National Academy of Sciences of the United States of America 97 (8): 4333-4338. 11 April 2000

Two-dimensional IR correlation spectroscopy: Sequential events in the unfolding process of the lamda Cro-V55C repressor protein.
Fabian, H. and Mantsch, H.H. and Schultz, C.P.
Proceedings of the National Academy of Sciences of the United States of America 96 : 13153-13158. 9 November 1999

Neutral evolution of mutational robustness.
van Nimwegen, E. and Crutchfield, J.P. and Huynen, M.
Proceedings of the National Academy of Sciences of the United States of America 96 : 9716-9720. 17 August 1999

Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases.
Beltinger, C. and Fulda, S. and Kammertoens, T. and Meyer, E. and Uckert, W. and Debatin, K.M.
Proceedings of the National Academy of Sciences of the United States of America 96 : 8699-8704. 20 July 1999

Separation of C/EBP alpha-mediated proliferation arrest and differentiation pathways.
Mueller, C. and Alunni-Fabroni, M. and Kowenz-Leutz, E. and Mo, X.M. and Tommasino, M. and Leutz, A.
Proceedings of the National Academy of Sciences of the United States of America 96 : 7276-7281. 22 June 1999

Conformational variants of class II MHC/peptide complexes induced by N- and C-terminal extensions of minimal peptide epitopes.
Roetzschke, O. and Falk, K. and Mack, J. and Lau, J.M. and Jung, G. and Strominger, J.L.
Proceedings of the National Academy of Sciences of the United States of America 96 : 7445-7450. 22 June 1999

Unexpected abundance of self-splicing introns in the genome of bacteriophage Twort: introns in multiple genes, a single gene with three introns, and exon skipping by group I ribozymes.
Landthaler, M. and Shub, D.A.
Proceedings of the National Academy of Sciences of the United States of America 96 (12): 7005-7010. 8 June 1999

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology.
Scherzinger, E. and Sittler, A. and Schweiger, K. and Heiser, V. and Lurz, R. and Hasenbank, R. and Bates, G.P. and Lehrach, H. and Wanker, E.E.
Proceedings of the National Academy of Sciences of the United States of America 96 (8): 4604-4609. 13 April 1999

Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen.
Schinke, M. and Baltatu, O. and Boehm, M. and Peters, J. and Rascher, W. and Bricca, G. and Lippoldt, A. and Ganten, D. and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 96 : 3975-3980. 30 March 1999

The Opitz syndrome gene product, MID1, associates with microtubules.
Schweiger, S. and Foerster, J. and Lehman, T. and Suckow, V. and Muller, Y.A. and Walter, G. and Davies, T. and Porter, H. and van Bokhoven, H. and Lunt, P.W. and Traub, P. and Ropers, H.H.
Proceedings of the National Academy of Sciences of the United States of America 96 : 2794-2799. 16 March 1999

Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes.
Baron, U. and Schnappinger, D. and Helbl, V. and Gossen, M. and Hillen, W. and Bujard, H.
Proceedings of the National Academy of Sciences of the United States of America 96 : 1013-1018. 2 February 1999

A pyrimidine-rich exonic splicing suppressor binds multiple RNA splicing factors and inhibits spliceosome assembly.
Zheng, Z.M. and Huynen, M. and Baker, C.C.
Proceedings of the National Academy of Sciences of the United States of America 95 (24): 14088-14093. 24 November 1998

Peptide design by artificial neural networks and computer-based evolutionary search.
Schneider, G. and Schrodl, W. and Wallukat, G. and Mueller, J. and Nissen, E. and Roenspeck, W. and Wrede, P. and Kunze, R.
Proceedings of the National Academy of Sciences of the United States of America 95 (21): 12179-12184. 13 October 1998

Copy number control of a transposable element, the I factor, a LINE-like element in Drosophila.
Chaboissiert, M.C. and Bucheton, A. and Finnegan, D.J.
Proceedings of the National Academy of Sciences of the United States of America 95 (20): 11781-11785. 29 September 1998

A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets.
Sander, M. and Griffen, S.C. and Huang, J. and German, M.S.
Proceedings of the National Academy of Sciences of the United States of America 95 (20): 11572-7. 29 September 1998

Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells.
Luo, G. and Ivics, Z. and Izsvak, Z. and Bradley, A.
Proceedings of the National Academy of Sciences of the United States of America 95 (18): 10769-10773. 1 September 1998

Deletion of long-range regulatory elements upstream of SOX9 causes campomelic dysplasia.
Wunderle, V.M. and Critcher, R. and Hastie, N. and Goodfellow, P.N. and Schedl, A.
Proceedings of the National Academy of Sciences of the United States of America 95 (18): 10649-10654. 1 September 1998

The Drosophila LIM-only gene, dLMO, is mutated in Beadex alleles and might represent an evolutionarily conserved function in appendage development.
Zeng, C. and Justice, N.J. and Abdelilah, S. and Chan, Y.M. and Jan, L.Y. and Jan, Y.N.
Proceedings of the National Academy of Sciences of the United States of America 95 (18): 10637-10642. 1 September 1998

ClC-5, the chloride channel mutated in Dent's disease, colocalizes with the proton pump in endocytotically active kidney cells.
Guenther, W. and Luechow, A. and Cluzeaud, F. and Vandewalle, A. and Jentsch, T.J.
Proceedings of the National Academy of Sciences of the United States of America 95 (14): 8075-8080. 7 July 1998

Structure and function of the Bacillus hybrid enzyme GluXyn-1: Native-like jellyroll fold preserved after insertion of autonomous globular domain.
Ay, J. and Goetz, F. and Borriss, R. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 95 (12): 6613-6618. 9 June 1998

Huntingtin aggregation monitored by dynamic light scattering.
Georgalis, Y. and Starikov, E.B. and Hollenbach, B. and Lurz, R. and Scherzinger, E. and Saenger, W. and Lehrach, H. and Wanker, E.E.
Proceedings of the National Academy of Sciences of the United States of America 95 (11): 6118-6121. 26 May 1998

Measuring genome evolution.
Huynen, M.A. and Bork, P.
Proceedings of the National Academy of Sciences of the United States of America 95 (11): 5849-5856. 26 May 1998

SMART, a simple modular architecture research tool: Identification of signaling domains.
Schultz, J. and Milpetz, F. and Bork, P. and Ponting, C.P.
Proceedings of the National Academy of Sciences of the United States of America 95 (11): 5857-5864. 26 May 1998

A substrate of the centisome 63 type III protein secretion system of Salmonella typhimurium is encoded by a cryptic bacteriophage.
Hardt, W.D. and Urlaub, H. and Galan, J.E.
Proceedings of the National Academy of Sciences of the United States of America 95 (5): 2574-2579. 3 March 1998

Superactivation of an immune response triggered by oligomerized T cell epitopes.
Roetzschke, O. and Falk, K. and Strominger, J.L.
Proceedings of the National Academy of Sciences of the United States of America 94 (26): 14642-14647. 23 December 1997

Insulin-like growth factors-I and -II differentially regulate endogenous acetylcholine release from the rat hippocampal formation.
Kar, S. and Seto, D. and Dore, S. and Hanisch, U. and Quirion, R.
Proceedings of the National Academy of Sciences of the United States of America 94 (25): 14054-14059. 9 December 1997

Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein.
Dhordain, P. and Albagli, O. and Lin, R.J. and Ansieau, S. and Quief, S. and Leutz, A. and Kerckaert, J.P. and Evans, R.M. and Leprince, D.
Proceedings of the National Academy of Sciences of the United States of America 94 (20): 10762-10767. 30 September 1997

Genetic influence on neurogenesis in the dentate gyrus of adult mice.
Kempermann, G. and Kuhn, H.G. and Gage, F.H.
Proceedings of the National Academy of Sciences of the United States of America 94 (19): 10409-10414. 16 September 1997

Transmembrane topology of a CLC chloride channel.
Schmidt-Rose, T. and Jentsch, T.J.
Proceedings of the National Academy of Sciences of the United States of America 94 (14): 7633-7638. 8 July 1997

Frequency-domain techniques enhance optical mammography. Initial clinical results.
Franceschini, M.A. and Moesta, K.T. and Fantini, S. and Gaida, G. and Gratton, E. and Jess, H. and Mantulin, W.W. and Seeber, M. and Schlag, P.M. and Kaschke, M.
Proceedings of the National Academy of Sciences of the United States of America 94 (12): 6468-6473. 10 June 1997

Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs.
Mushegian, A.R. and Bassett, D.E. and Boguski, M.S. and Bork, P. and Koonin, E.V.
Proceedings of the National Academy of Sciences of the United States of America 94 : 5831-5836. 1 January 1997

Intrastriatally injected c-fos antisense oligonucleotide interferes with striatonigral but not striatopallidal gamma-aminobutyric acid transmission in the conscious rat.
Sommer, W. and Rimondini, R. and O'Connor, W. and Hansson, A. and Ungerstedt, U. and Fuxe, K.
Proceedings of the National Academy of Sciences of the United States of America 93 (24): 14134-14139. 26 November 1996

Heteromultimeric CLC chloride channels with novel properties.
Lorenz, C. and Pusch, M. and Jentsch, T.J.
Proceedings of the National Academy of Sciences of the United States of America 93 (23): 13362-13366. 12 November 1996

Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene.
Tucker, K.L. and Talbot, D. and Lee, M.A. and Leonhardt, H. and Jaenisch, R.
Proceedings of the National Academy of Sciences of the United States of America 93 (23): 12920-12925. 12 November 1996

Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice.
Kistner, A. and Gossen, M. and Zimmermann, F. and Jerecic, J. and Ullmer, C. and Lubbert, H. and Bujard, H.
Proceedings of the National Academy of Sciences of the United States of America 93 (20): 10933-10938. 1 October 1996

Defective forebrain development in mice lacking gp330/megalin.
Willnow, T.E. and Hilpert, J. and Armstrong, S.A. and Rohlmann, A. and Hammer, R.E. and Burns, D.K. and Herz, J.
Proceedings of the National Academy of Sciences of the United States of America 93 (16): 8460-8464. 6 August 1996

Identification of functional domains and evolution of Tc1-like transposable elements.
Ivics, Z. and Izsvak, Z. and Minter, A. and Hackett, P.B.
Proceedings of the National Academy of Sciences of the United States of America 93 (10): 5008-5013. 14 May 1996

Induction of cellular immunity in chimpanzees to human tumor associated antigen mucin by vaccination with MUC-1 cDNA-transfected Epstein-Barr virus-immortalized autologous B cells.
Pecher, G. and Finn, O.J.
Proceedings of the National Academy of Sciences of the United States of America 93 (4): 1699-1704. 20 February 1996

DANA elements: a family of composite, tRNA-derived short interspersed DNA elements associated with mutational activities in zebrafish (Danio rerio).
Izsvak, Z. and Ivics, Z. and Garcia-Estefania, D. and Fahrenkrug, S.C. and Hackett, P.B.
Proceedings of the National Academy of Sciences of the United States of America 93 (3): 1077-1081. 6 February 1996

Efficient gene transfer into human hepatocytes by baculovirus vectors.
Hofmann, C. and Sandig, V. and Jennings, G. and Rudolph, M. and Schlag, P.M. and Strauss, M.
Proceedings of the National Academy of Sciences of the United States of America 92 (22): 10099-10103. 24 October 1995

VIP21/caveolin is a cholesterol-binding protein.
Murata, M. and Peraenen, J. and Schreiner, R. and Wieland, F. and Kurzchalia, T.V. and Simons, K.
Proceedings of the National Academy of Sciences of the United States of America 92 (22): 10339-10343. 24 October 1995

Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10.
Kreutz, R. and Hübner, N. and James, M.R. and Bihoreau, M.T. and Gauguier, D. and Lathrop, G.M. and Ganten, D. and Lindpaintner, K.
Proceedings of the National Academy of Sciences of the United States of America 92 (19): 8778-8782. 12 September 1995

Functional expression of low density lipoprotein receptor- related protein is controlled by receptor-associated protein in vivo.
Willnow, T.E. and Armstrong, S.A. and Hammer, R.E. and Herz, J.
Proceedings of the National Academy of Sciences of the United States of America 92 (10): 4537-4541. 9 May 1995

Lactation is disrupted by alpha-lactalbumin deficiency and can by restored by human alpha-lactalbumin gene replacement in mice.
Stacey, A. and Schnieke, A. and Kerr, M. and Scott, A. and McKee, C. and Cottingham, I. and Binas, B. and Wilde, C. and Colman, A.
Proceedings of the National Academy of Sciences of the United States of America 92 (7): 2835-2839. 28 March 1995

A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development.
Riethmacher, D. and Brinkmann, V. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 92 (3): 855-859. 31 January 1995

Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.
Weidner, K.M. and Sachs, M. and Riethmacher, D. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 92 : 2597-2601. 1 January 1995

Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.
Furth, P.A. and Onge, S.T. and Boger, H. and Gruss, P. and Gossen, M. and Kistner, A. and Bujard, H. and Hennighausen, L.
Proceedings of the National Academy of Sciences of the United States of America 91 (20): 9302-9306. 27 September 1994

Two highly homologous members of the ClC chloride channel family in both rat and human kidney.
Kieferle, S. and Fong, P. and Bens, M. and Vandewalle, A. and Jentsch, T.J.
Proceedings of the National Academy of Sciences of the United States of America 91 (15): 6943-6947. 19 July 1994

Crystal structure of CspA, the major cold shock protein of Escherichia coli.
Schindelin, H. and Jiang, W. and Inouye, M. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 91 (11): 5119-5123. 24 May 1994

Cyclin D1 expression is regulated by the retinoblastoma protein.
Mueller, H. and Lukas, J. and Schneider, A. and Warthoe, P. and Bartek, J. and Eilers, M. and Strauss, M.
Proceedings of the National Academy of Sciences of the United States of America 91 (8): 2945-2949. 12 April 1994

E-cadherin gene mutations in human gastric carcinoma cell lines.
Oda, T. and Kanai, Y. and Oyama, T. and Yoshiura, K. and Shimoyama, Y. and Birchmeier, W. and Sugimura, T. and Hirohashi, S.
Proceedings of the National Academy of Sciences of the United States of America 91 (5): 1858-1862. 1 March 1994

Role of adrenal renin in the regulation of adrenal steroidogenesis corticotropin.
Sander, M. and Ganten, D. and Mellon, S.H.
Proceedings of the National Academy of Sciences of the United States of America 91 (1): 148-152. 4 January 1994

Native-like in vivo folding of a circularly permuted jellyroll protein shown by crystal structure analysis.
Hahn, M. and Piotukh, K. and Borriss, R. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 91 : 10417-10421. 1 January 1994

Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development.
Meyer, D. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 91 : 1064-1068. 1 January 1994

Allele-specific peptide ligand motifs of HLA-C molecules.
Falk, K. and Roetzschke, O. and Grahovac, B. and Schendel, D. and Stevanovic, S. and Gnau, V. and Jung, G. and Strominger, J.L. and Rammensee, H.G.
Proceedings of the National Academy of Sciences of the United States of America 90 (24): 12005-12009. 15 December 1993

Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.
Corral, J. and Forster, A. and Thompson, S. and Lampert, F. and Kaneko, Y. and Slater, R. and Kroes, W.G. and van der Schoot, C.E. and Ludwig, W.D. and Karpas, A. and Pocock, C. and Cotter, F. and Rabitts, T.H.
Proceedings of the National Academy of Sciences of the United States of America 90 (18): 8538-8542. 15 September 1993

A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2.
Thierfelder, L.H. and MacRae, C. and Watkins, H. and Tomfohrde, J. and Williams, M. and McKenna, W. and Bohm, K. and Noeske, G. and Schlepper, M. and Bowcock, A.
Proceedings of the National Academy of Sciences of the United States of America 90 (13): 6270-6274. 1 July 1993

Mechanisms of rejection induced by tumor cell-targeted gene transfer of interleukin 2, interleukin 4, interleukin 7, tumor necrosis factor, or interferon-gamma.
Hock, H. and Dorsch, M. and Kunzendorf, U. and Qin, Z. and Diamantstein, T. and Blankenstein, T.
Proceedings of the National Academy of Sciences of the United States of America 90 (7): 2774-2778. 1 April 1993

Molecular and active-site structure of a Bacillus (1-3,1-4)-beta-glucanase.
Keitel, T. and Simon, O. and Borriss, R. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 90 : 5287-5291. 1 January 1993

An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins.
Bork, P. and Sander, C. and Valencia, A.
Proceedings of the National Academy of Sciences of the United States of America 89 (16): 7290-7294. 15 August 1992

Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes.
Ganten, D. and Wagner, J. and Zeh, K. and Bader, M. and Michel, J.B. and Paul, M. and Zimmermann, F. and Ruf, P. and Hilgenfeldt, U. and Ganten, U. and Kaling, M. and Bachmann, S. and Fukamizu, A. and Mullins, J.J. and Murakami, K.
Proceedings of the National Academy of Sciences of the United States of America 89 : 7806-7810. August 1992

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
Gossen, M. and Bujard, H.
Proceedings of the National Academy of Sciences of the United States of America 89 (12): 5547-5551. 15 June 1992

Proposed acquisition of an animal protein domain by bacteria.
Bork, P. and Doolittle, R.F.
Proceedings of the National Academy of Sciences of the United States of America 89 : 8990-8994. 1 January 1992

A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis.
Hartmann, G. and Naldini, L. and Weidner, K.M. and Sachs, M. and Vigna, E. and Comoglio, P.M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 89 : 11574-11578. 1 January 1992

The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappaB DNA binding.
Hatada, E.N. and Nieters, A. and Wulczyn, F.G. and Naumann, M. and Meyer, R. and Nucifora, G. and McKeithan, T.W. and Scheidereit, C.
Proceedings of the National Academy of Sciences of the United States of America 89 (6): 2489-2493. 1 January 1992

Completely functional double-barreled chloride channel expressed from a single Torpedo cDNA.
Bauer, C.K. and Steinmeyer, K. and Schwarz, J.R. and Jentsch, T.J.
Proceedings of the National Academy of Sciences of the United States of America 88 (24): 11052-11056. 15 December 1991

Editorial

Michael S. Neuberger 1953-2013.
Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 111 (8): 2862-2863. 25 February 2014

Using machine learning to identify disease-relevant regulatory RNAs.
Ohler, U.
Proceedings of the National Academy of Sciences of the United States of America 110 (39): 15516-15517. 24 September 2013

Structural insights into membrane fusion at the endoplasmic reticulum.
Daumke, O. and Praefcke, G.J.
Proceedings of the National Academy of Sciences of the United States of America 108 (6): 2175-2176. 8 February 2011

Impacting our young.
Marder, E. and Kettenmann, H. and Grillner, S.
Proceedings of the National Academy of Sciences of the United States of America 107 (50): 21233. 14 December 2010

Polyglutamine fibrillogenesis: The pathway unfolds.
Ross, C.A. and Poirier, M.A. and Wanker, E.E. and Amzel, M.
Proceedings of the National Academy of Sciences of the United States of America 100 (1): 1-3. 7 January 2003

Other

George Klein: 1925-2016.
Rajewsky, K.
National Academy of Sciences. 28 March 2017

This list was generated on Thu Mar 28 02:29:26 2024 CET.
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