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Unravelling the collateral damage of antibiotics on gut bacteria.
Maier, L. and Goemans, C.V. and Wirbel, J. and Kuhn, M. and Eberl, C. and Pruteanu, M. and Müller, P. and Garcia-Santamarina, S. and Cacace, E. and Zhang, B. and Gekeler, C. and Banerjee, T. and Anderson, E.E. and Milanese, A. and Löber, U. and Forslund, S.K. and Patil, K.R. and Zimmermann, M. and Stecher, B. and Zeller, G. and Bork, P. and Typas, A.
Nature 13 October 2021 (In Press)

Using DNA sequencing data to quantify T cell fraction and therapy response.
Bentham, R. and Litchfield, K. and Watkins, T.B.K. and Lim, E.L. and Rosenthal, R. and Martínez-Ruiz, C. and Hiley, C.T. and Bakir, M.A. and Salgado, R. and Moore, D.A. and Jamal-Hanjani, M. and Swanton, C. and McGranahan, N.
Nature 597 (7877): 555-560. 23 September 2021

Bioaccumulation of therapeutic drugs by human gut bacteria.
Klünemann, M. and Andrejev, S. and Blasche, S. and Mateus, A. and Phapale, P. and Devendran, S. and Vappiani, J. and Simon, B. and Scott, T.A. and Kafkia, E. and Konstantinidis, D. and Zirngibl, K. and Mastrorilli, E. and Banzhaf, M. and Mackmull, M.T. and Hövelmann, F. and Nesme, L. and Brochado, A.R. and Maier, L. and Bock, T. and Periwal, V. and Kumar, M. and Kim, Y. and Tramontano, M. and Schultz, C. and Beck, M. and Hennig, J. and Zimmermann, M. and Sévin, D.C. and Cabreiro, F. and Savitski, M.M. and Bork, P. and Typas, A. and Patil, K.R.
Nature 597 : 533–538. 23 September 2021

Virus-induced senescence is driver and therapeutic target in COVID-19.
Lee, S. and Yu, Y. and Trimpert, J. and Benthani, F. and Mairhofer, M. and Richter-Pechanska, P. and Wyler, E. and Belenki, D. and Kaltenbrunner, S. and Pammer, M. and Kausche, L. and Firsching, T.C. and Dietert, K. and Schotsaert, M. and Martínez-Romero, C. and Singh, G. and Kunz, S. and Niemeyer, D. and Ghanem, R. and Salzer, H.J.F. and Paar, C. and Mülleder, M. and Uccellini, M. and Michaelis, E.G. and Khan, A. and Lau, A. and Schönlein, M. and Habringer, A. and Tomasits, J. and Adler, J.M. and Kimeswenger, S. and Gruber, A.D. and Hoetzenecker, W. and Steinkellner, H. and Purfuerst, B. and Motz, R. and Di Pierro, F. and Lamprecht, B. and Osterrieder, N. and Landthaler, M. and Drosten, C. and García-Sastre, A. and Langer, R. and Ralser, M. and Eils, R. and Reimann, M. and Fan, D.N.Y. and Schmitt, C.A.
Nature 13 September 2021 (In Press)

Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
Willnow, D. and Benary, U. and Margineanu, A. and Vignola, M.L. and Konrath, F. and Pongrac, I.M. and Karimaddini, Z. and Vigilante, A. and Wolf, J. and Spagnoli, F.M.
Nature 597 (7874): 87-91. 2 September 2021

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Ren, A.A. and Snellings, D.A. and Su, Y.S. and Hong, C.C. and Castro, M. and Tang, A.T. and Detter, M.R. and Hobson, N. and Girard, R. and Romanos, S. and Lightle, R. and Moore, T. and Shenkar, R. and Benavides, C. and Beaman, M.M. and Mueller-Fielitz, H. and Chen, M. and Mericko, P. and Yang, J. and Sung, D.C. and Lawton, M.T. and Ruppert, M. and Schwaninger, M. and Körbelin, J. and Potente, M. and Awad, I.A. and Marchuk, D.A. and Kahn, M.L.
Nature 594 (7862): :271-276. 10 June 2021

Swarm Learning for decentralized and confidential clinical machine learning.
Warnat-Herresthal, S. and Schultze, H. and Shastry, K.L. and Manamohan, S. and Mukherjee, S. and Garg, V. and Sarveswara, R. and Händler, K. and Pickkers, P. and Aziz, N.A. and Ktena, S. and Tran, F. and Bitzer, M. and Ossowski, S. and Casadei, N. and Herr, C. and Petersheim, D. and Behrends, U. and Kern, F. and Fehlmann, T. and Schommers, P. and Lehmann, C. and Augustin, M. and Rybniker, J. and Altmüller, J. and Mishra, N. and Bernardes, J.P. and Krämer, B. and Bonaguro, L. and Schulte-Schrepping, J. and De Domenico, E. and Siever, C. and Kraut, M. and Desai, M. and Monnet, B. and Saridaki, M. and Siegel, C.M. and Drews, A. and Nuesch-Germano, M. and Theis, H. and Heyckendorf, J. and Schreiber, S. and Kim-Hellmuth, S. and Nattermann, J. and Skowasch, D. and Kurth, I. and Keller, A. and Bals, R. and Nürnberg, P. and Rieß, O. and Rosenstiel, P. and Netea, M.G. and Theis, F. and Mukherjee, S. and Backes, M. and Aschenbrenner, A.C. and Ulas, T. and Breteler, M.M.B. and Giamarellos-Bourboulis, E.J. and Kox, M. and Becker, M. and Cheran, S. and Woodacre, M.S. and Goh, E.L. and Schultze, J.L.
Nature 594 (7862): 265-270. 10 June 2021

Skin-resident innate lymphoid cells converge on a pathogenic effector state.
Bielecki, P. and Riesenfeld, S.J. and Hütter, J.C. and Torlai Triglia, E. and Kowalczyk, M.S. and Ricardo-Gonzalez, R.R. and Lian, M. and Amezcua Vesely, M.C. and Kroehling, L. and Xu, H. and Slyper, M. and Muus, C. and Ludwig, L.S. and Christian, E. and Tao, L. and Kedaigle, A.J. and Steach, H.R. and York, A.G. and Skadow, M.H. and Yaghoubi, P. and Dionne, D. and Jarret, A. and McGee, H.M. and Porter, C.B.M. and Licona-Limón, P. and Bailis, W. and Jackson, R. and Gagliani, N. and Gasteiger, G. and Locksley, R.M. and Regev, A. and Flavell, R.A.
Nature 592 (7852): 128-132. 1 April 2021

Arterialization requires the timely suppression of cell growth.
Luo, W. and Garcia-Gonzalez, I. and Fernández-Chacón, M. and Casquero-Garcia, V. and Sanchez-Muñoz, M.S. and Mühleder, S. and Garcia-Ortega, L. and Andrade, J. and Potente, M. and Benedito, R.
Nature 589 (7842): 437-441. 21 January 2021


Cells of the adult human heart.
Litviňuková, M. and Talavera-López, C. and Maatz, H. and Reichart, D. and Worth, C.L. and Lindberg, E.L. and Kanda, M. and Polanski, K. and Heinig, M. and Lee, M.l and Nadelmann, E.R. and Roberts, K. and Tuck, L. and Fasouli, E.S. and DeLaughter, D.M. and McDonough, B. and Wakimoto, H. and Gorham, J.M. and Samari, S. and Mahbubani, K.T. and Saeb-Parsy, K. and Patone, G. and Boyle, J.J. and Zhang, H. and Zhang, H. and Viveiros, A. and Oudit, G.Y. and Bayraktar, O. and Seidman, J.G. and Seidman, C.E. and Noseda, M. and Hubner, N. and Teichmann, S.A.
Nature 588 (7838): 466-472. 17 December 2020

Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.
Jayavelu, A.K. and Schnöder, T.M. and Perner, F. and Herzog, C. and Meiler, A. and Krishnamoorthy, G. and Huber, N. and Mohr, J. and Edelmann-Stephan, B. and Austin, R. and Brandt, S. and Palandri, F. and Schröder, N. and Isermann, B. and Edlich, F. and Sinha, A.U. and Ungelenk, M. and Hübner, C.A. and Zeiser, R. and Rahmig, S. and Waskow, C. and Coldham, I. and Ernst, T. and Hochhaus, A. and Jilg, S. and Jost, P.J. and Mullally, A. and Bullinger, L. and Mertens, P.R. and Lane, S.W. and Mann, M. and Heidel, F.H.
Nature 588 (7836): 157-163. 3 December 2020

LifeTime and improving European healthcare through cell-based interceptive medicine.
Rajewsky, N. and Almouzni, G. and Gorski, S.A. and Aerts, S. and Amit, I. and Bertero, M.G. and Bock, C. and Bredenoord, A.L. and Cavalli, G. and Chiocca, S. and Clevers, H. and De Strooper, B. and Eggert, A. and Ellenberg, J. and Fernández, X.M. and Figlerowicz, M. and Gasser, S.M. and Hubner, N. and Kjems, J. and Knoblich, J.A. and Krabbe, G. and Lichter, P. and Linnarsson, S. and Marine, J.C. and Marioni, J. and Marti-Renom, M.A. and Netea, M.G. and Nickel, D. and Nollmann, M. and Novak, H.R. and Parkinson, H. and Piccolo, S. and Pinheiro, I. and Pombo, A. and Popp, C. and Reik, W. and Roman-Roman, S. and Rosenstiel, P. and Schultze, J.L. and Stegle, O. and Tanay, A. and Testa, G. and Thanos, D. and Theis, F.J. and Torres-Padilla, M.E. and Valencia, A. and Vallot, C. and van Oudenaarden, A. and Vidal, M. and Voet, T.
Nature 587 (7834): 377-386. 19 November 2020

Pervasive chromosomal instability and karyotype order in tumour evolution.
Watkins, T.B.K. and Lim, E.L. and Petkovic, M. and Elizalde, S. and Birkbak, N.J. and Wilson, G.A. and Moore, D.A. and Grönroos, E. and Rowan, A. and Dewhurst, S.M. and Demeulemeester, J. and Dentro, S.C. and Horswell, S. and Au, L. and Haase, K. and Escudero, M. and Rosenthal, R. and Bakir, M.A. and Xu, H. and Litchfield, K. and Lu, W.T. and Mourikis, T.P. and Dietzen, M. and Spain, L. and Cresswell, G.D. and Biswas, D. and Lamy, P. and Nordentoft, I. and Harbst, K. and Castro-Giner, F. and Yates, L.R. and Caramia, F. and Jaulin, F. and Vicier, C. and Tomlinson, I.P.M. and Brastianos, P.K. and Cho, R.J. and Bastian, B.C. and Dyrskjøt, L. and Jönsson, G.B. and Savas, P. and Loi, S. and Campbell, P.J. and Andre, F. and Luscombe, N.M. and Steeghs, N. and Tjan-Heijnen, V.C.G. and Szallasi, Z. and Turajlic, S. and Jamal-Hanjani, M. and Van Loo, P. and Bakhoum, S.F. and Schwarz, R.F. and McGranahan, N. and Swanton, C.
Nature 587 (7832): 126-132. 5 November 2020

Rescue of oxytocin response and social behaviour in a mouse model of autism.
Hörnberg, H. and Pérez-Garci, E. and Schreiner, D. and Hatstatt-Burklé, L. and Magara, F. and Baudouin, S. and Matter, A. and Nacro, K. and Pecho-Vrieseling, E. and Scheiffele, P.
Nature 584 (7820): 252-256. 13 August 2020

Epigenetic regulator function through mouse gastrulation.
Grosswendt, S. and Kretzmer, H. and Smith, Z.D. and Kumar, A.S. and Hetzel, S. and Wittler, L. and Klages, S. and Timmermann, B. and Mukherji, S. and Meissner, A.
Nature 584 (7819): 102-108. 6 August 2020

Statin therapy is associated with lower prevalence of gut microbiota dysbiosis.
Vieira-Silva, S. and Falony, G. and Belda, E. and Nielsen, T. and Aron-Wisnewsky, J. and Chakaroun, R. and Forslund, S.K. and Assmann, K. and Valles-Colomer, M. and Nguyen, T..D. and Proost, S. and Prifti, E. and Tremaroli, V. and Pons, N. and Le Chatelier, E. and Andreelli, F. and Bastard, J.P. and Coelho, L.P. and Galleron, N. and Hansen, T.H. and Hulot, J.S. and Lewinter, C. and Pedersen, H.K. and Quinquis, B. and Rouault, C. and Roume, H. and Salem, J.E. and Søndertoft, N.B. and Touch, S. and Dumas, M.E. and Ehrlich, S.D. and Galan, P. and Gøtze, J.P. and Hansen, T. and Holst, J.J. and Køber, L. and Letunic, I. and Nielsen, J. and Oppert, J.M. and Stumvoll, M. and Vestergaard, H. and Zucker, J.D. and Bork, P. and Pedersen, O. and Bäckhed, F. and Clément, K. and Raes, J.
Nature 581 (7808): 310-315. 21 May 2020

Pan-cancer analysis of whole genomes.

Nature 578 (7793): 82-93. 6 February 2020

Genomic basis for RNA alterations in cancer.
Calabrese, C. and Davidson, N.R. and Demircioğlu, D. and Fonseca, N.A. and He, Y. and Kahles, A. and Lehmann, K.V. and Liu, F. and Shiraishi, Y. and Soulette, C.M. and Urban, L. and Greger, L. and Li, S. and Liu, D. and Perry, M.D. and Xiang, Q. and Zhang, F. and Zhang, J. and Bailey, P. and Erkek, S. and Hoadley, K.A. and Hou, Y. and Huska, M.R. and Kilpinen, H. and Korbel, J.O. and Marin, M.G. and Markowski, J. and Nandi, T. and Pan-Hammarström, Q. and Pedamallu, C.S. and Siebert, R. and Stark, S.G. and Su, H. and Tan, P. and Waszak, S.M. and Yung, C. and Zhu, S. and Awadalla, P. and Creighton, C.J. and Meyerson, M. and Ouellette, B.F.F. and Wu, K. and Yang, H. and Brazma, A. and Brooks, A.N. and Göke, J. and Rätsch, G. and Schwarz, R.F. and Stegle, O. and Zhang, Z.
Nature 578 (7793): 129-136. 6 February 2020


Gene expression cartography.
Nitzan, M. and Karaiskos, N. and Friedman, N. and Rajewsky, N.
Nature 576 (7785): 132-137. 5 December 2019

The advent and rise of monoclonal antibodies.
Rajewsky, K.
Nature 575 (7781): 47-49. November 2019

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.
Lee, J. and Termglinchan, V. and Diecke, S. and Itzhaki, I. and Lam, C.K. and Garg, P. and Lau, E. and Greenhaw, M. and Seeger, T. and Wu, H. and Zhang, J.Z and Chen, X. and Gil, I.P. and Ameen, M. and Sallam, K. and Rhee, J.W. and Churko, J.M. and Chaudhary, R. and Chour, T. and Wang, P.J. and Snyder, M.P. and Chang, H.Y. and Karakikes, I. and Wu, J.C.
Nature 572 (7769): 335-340. 15 August 2019

Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1.
Faelber, K. and Dietrich, L. and Noel, J.K. and Wollweber, F. and Pfitzner, A.K. and Mühleip, A. and Sánchez, R. and Kudryashev, M. and Chiaruttini, N. and Lilie, H. and Schlegel, J. and Rosenbaum, E. and Hessenberger, M. and Matthaeus, C. and Kunz, S. and von der Malsburg, A. and Noé, F. and Roux, A. and van der Laan, M. and Kühlbrandt, W. and Daumke, O.
Nature 571 (7765): 429-433. 18 July 2019

Molecular recording of mammalian embryogenesis.
Chan, M.M. and Smith, Z.D. and Grosswendt, S. and Kretzmer, H. and Norman, T.M. and Adamson, B. and Jost, M. and Quinn, J.J. and Yang, D. and Jones, M.G. and Khodaverdian, A. and Yosef, N. and Meissner, A. and Weissman, J.S.
Nature 570 (7759): 77-82. 6 June 2019

Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts.
Eckert, M.A. and Coscia, F. and Chryplewicz, A. and Chang, J.W. and Hernandez, K.M. and Pan, S. and Tienda, S.M. and Nahotko, D.A. and Li, G. and Blaženović, I. and Lastra, R.R. and Curtis, M. and Yamada, S.D. and Perets, R. and McGregor, S.M. and Andrade, J. and Fiehn, O. and Moellering, R.E. and Mann, M. and Lengyel, E.
Nature 569 (7758): 723-728. 30 May 2019

Nitrosative stress drives heart failure with preserved ejection fraction.
Schiattarella, G.G. and Altamirano, F. and Tong, D. and French, K.M. and Villalobos, E. and Kim, S.Y. and Luo, X. and Jiang, N. and May, H.I. and Wang, Z.V. and Hill, T.M. and Mammen, P.P.A. and Huang, J. and Lee, D.I. and Hahn, V.S. and Sharma, K. and Kass, D.A. and Lavandero, S. and Gillette, T.G. and Hill, J.A.
Nature 568 (7752): 351-356. 18 April 2019

Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.
Farrelly, L.A. and Thompson, R.E. and Zhao, S. and Lepack, A.E. and Lyu, Y. and Bhanu, N.V. and Zhang, B. and Loh, Y.H.E. and Ramakrishnan, A. and Vadodaria, K.C. and Heard, K.J. and Erikson, G. and Nakadai, T. and Bastle, R.M. and Lukasak, B.J. and Zebroski, H. and Alenina, N. and Bader, M. and Berton, O. and Roeder, R.G. and Molina, H. and Gage, F.H. and Shen, L. and Garcia, B.A. and Li, H. and Muir, T.W. and Maze, I.
Nature 567 (7749): 535-539. 28 March 2019

Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.
Messal, H.A. and Alt, S. and Ferreira, R.M.M. and Gribben, C. and Wang, V.M.Y. and Cotoi, C.G. and Salbreux, G. and Behrens, A.
Nature 566 (7742): 126-130. 7 February 2019


Structure and function of the global topsoil microbiome.
Bahram, M. and Hildebrand, F. and Forslund, S.K. and Anderson, J.L. and Soudzilovskaia, N.A. and Bodegom, P.M. and Bengtsson-Palme, J. and Anslan, S. and Coelho, L.P. and Harend, H. and Huerta-Cepas, J. and Medema, M.H. and Maltz, M.R. and Mundra, S. and Olsson, P.A. and Pent, M. and Põlme, S. and Sunagawa, S. and Ryberg, M. and Tedersoo, L. and Bork, P.
Nature 560 (7717): 233-237. 9 August 2018

Species-specific activity of antibacterial drug combinations.
Brochado, A.R. and Telzerow, A. and Bobonis, J. and Banzhaf, M. and Mateus, A. and Selkrig, J. and Huth, E. and Bassler, S. and Zamarreño Beas, J. and Zietek, M. and Ng, N. and Foerster, S. and Ezraty, B. and Py, B. and Barras, F. and Savitski, M.M. and Bork, P. and Göttig, S. and Typas, A.
Nature 559 (7713): 259-263. July 2018

Kinase-controlled phase transition of membraneless organelles in mitosis.
Rai, A.K. and Chen, J.X. and Selbach, M. and Pelkmans, L.
Nature 559 (7713): 211-216. July 2018

Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.
Fernández, Á.F. and Sebti, S. and Wei, Y. and Zou, Z. and Shi, M. and McMillan, K.L. and He, C. and Ting, T. and Liu, Y. and Chiang, W.C. and Marciano, D.K. and Schiattarella, G.G. and Bhagat, G. and Moe, O.W. and Hu, M.C. and Levine, B.
Nature 558 (7708): 136-140. 7 June 2018

Extensive impact of non-antibiotic drugs on human gut bacteria.
Maier, L. and Pruteanu, M. and Kuhn, M. and Zeller, G. and Telzerow, A. and Anderson, E.E. and Brochado, A.R. and Fernandez, K.C. and Dose, H. and Mori, H. and Patil, K.R. and Bork, P. and Typas, A.
Nature 555 (7698): 623-628. 29 March 2018

Senescence-associated reprogramming promotes cancer stemness.
Milanovic, M. and Fan, D.N.Y. and Belenki, D. and Däbritz, J.H.M. and Zhao, Z. and Yu, Y. and Dörr, J.R. and Dimitrova, L. and Lenze, D. and Monteiro Barbosa, I.A. and Mendoza-Parra, M.A. and Kanashova, T. and Metzner, M. and Pardon, K. and Reimann, M. and Trumpp, A. and Dörken, B. and Zuber, J. and Gronemeyer, H. and Hummel, M. and Dittmar, G. and Lee, S. and Schmitt, C.A.
Nature 553 (7686): 96-100. 4 January 2018


IL11 is a crucial determinant of cardiovascular fibrosis.
Schafer, S. and Viswanathan, S. and Widjaja, A.A. and Lim, W.W. and Moreno-Moral, A. and DeLaughter, D.M. and Ng, B. and Patone, G. and Chow, K. and Khin, E. and Tan, J. and Chothani, S.P. and Ye, L. and Rackham, O.J. and Ko, N.S. and Sahib, N.E. and Pua, C.J. and Zhen, N.T. and Xie, C. and Wang, M. and Maatz, H. and Lim, S. and Saar, K. and Blachut, S. and Petretto, E. and Schmidt, S. and Putoczki, T. and Guimarães-Camboa, N. and Wakimoto, H. and van Heesch, S. and Sigmundsson, K. and Lim, S.L. and Soon, J.L. and Chao, V.T. and Chua, Y.L. and Tan, T.E. and Evans, S.M. and Loh, Y.J. and Jamal, M.H. and Ong, K.K. and Chua, K.C. and Ong, B.H. and Chakaramakkil, M.J. and Seidman, J.G. and Seidman, C.E. and Hubner, N. and Sin, K.Y. and Cook, S.A.
Nature 552 (7683): 110-115. 7 December 2017

Salt-responsive gut commensal modulates T(H)17 axis and disease.
Wilck, N. and Matus, M.G. and Kearney, S.M. and Olesen, S.W. and Forslund, K. and Bartolomaeus, H. and Haase, S. and Mähler, A. and Balogh, A. and Markó, L. and Vvedenskaya, O. and Kleiner, F.H. and Tsvetkov, D. and Klug, L. and Costea, P.I. and Sunagawa, S. and Maier, L. and Rakova, N. and Schatz, V. and Neubert, P. and Frätzer, C. and Krannich, A. and Gollasch, M. and Grohme, D.A. and Côrte-Real, B.F. and Gerlach, R.G. and Basic, M. and Typas, A. and Wu, C. and Titze, J.M. and Jantsch, J. and Boschmann, M. and Dechend, R. and Kleinewietfeld, M. and Kempa, S. and Bork, P. and Linker, R.A. and Alm, E.J. and Müller, D.N.
Nature 551 (7682): 585-589. 30 November 2017

Single-molecule imaging reveals receptor-G protein interactions at cell surface hot spots.
Sungkaworn, T. and Jobin, M.L. and Burnecki, K. and Weron, A. and Lohse, M.J. and Calebiro, D.
Nature 550 (7677): 543-547. 26 October 2017

A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
Elling, U. and Wimmer, R.A. and Leibbrandt, A. and Burkard, T. and Michlits, G. and Leopoldi, A. and Micheler, T. and Abdeen, D. and Zhuk, S. and Aspalter, I.M. and Handl, C. and Liebergesell, J. and Hubmann, M. and Husa, A.M. and Kinzer, M. and Schuller, N. and Wetzel, E. and van de Loo, N. and Martinez, J.A.Z. and Estoppey, D. and Riedl, R. and Yang, F. and Fu, B. and Dechat, T. and Ivics, Z. and Agu, C.A. and Bell, O. and Blaas, D. and Gerhardt, H. and Hoepfner, D. and Stark, A. and Penninger, J.M.
Nature 550 (7674): 114-118. 5 October 2017

The 4D nucleome project.
Dekker, J. and Belmont, A.S. and Guttman, M. and Leshyk, V.O. and Lis, J.T. and Lomvardas, S. and Mirny, L.A. and O'Shea, C.C. and Park, P.J. and Ren, B. and Politz, J.C.R. and Shendure, J. and Zhong, S.
Nature 549 (7671): 219-226. 14 September 2017

Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.
Pieper, K. and Tan, J. and Piccoli, L. and Foglierini, M. and Barbieri, S. and Chen, Y. and Silacci-Fregni, C. and Wolf, T. and Jarrossay, D. and Anderle, M. and Abdi, A. and Ndungu, F.M. and Doumbo, O.K. and Traore, B. and Tran, T.M. and Jongo, S. and Zenklusen, I. and Crompton, P.D. and Daubenberger, C. and Bull, P.C. and Sallusto, F. and Lanzavecchia, A.
Nature 548 (7669): 597-601. 31 August 2017

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.
Pei, W. and Feyerabend, T.B. and Rössler, J. and Wang, X. and Postrach, D. and Busch, K. and Rode, I. and Klapproth, K. and Dietlein, N. and Quedenau, C. and Chen, W. and Sauer, S. and Wolf, S. and Höfer, T. and Rodewald, H.Re.
Nature 548 (7668): 456-460. 24 August 2017

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.
Sigal, M. and Logan, C.Y. and Kapalczynska, M. and Mollenkopf, H.J. and Berger, H. and Wiedenmann, B. and Nusse, R. and Amieva, M.R. and Meyer, T.F.
Nature 548 (7668): 451-455. 24 August 2017

Cell cycle: continuous chromatin changes.
Beagrie, R.A. and Pombo, A.
Nature 547 (7661): 34-35. 6 July 2017

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.
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Nature 546 (7657): 302-306. 8 June 2017

Phylogenetic ctDNA analysis depicts early stage lung cancer evolution.
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Nature 545 (7655): 446-451. 25 May 2017

FGF-dependent metabolic control of vascular development.
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Nature 545 (7653): 224-228. 11 May 2017

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
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Nature 545 (7652): 98-102. 4 May 2017

Complex multi-enhancer contacts captured by genome architecture mapping.
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Nature 543 (7646): 519-524. 23 March 2017

Hypoxia induces heart regeneration in adult mice.
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Nature 541 (7636): 222-227. 12 January 2017


Formation of new chromatin domains determines pathogenicity of genomic duplications.
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Nature 538 (7624): 265-269. 13 October 2016

Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses.
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Nature 537 (7622): 689-693. 29 September 2016

Human gut microbes impact host serum metabolome and insulin sensitivity.
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Nature 535 (7612): 376-381. 21 July 2016

Proteogenomics connects somatic mutations to signalling in breast cancer.
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Nature 534 (7605): 55-62. 2 June 2016

Plankton networks driving carbon export in the oligotrophic ocean.
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Nature 532 (7600): 465-470. 28 April 2016

FOXO1 couples metabolic activity and growth state in the vascular endothelium.
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Nature 529 (7585): 216-220. 14 January 2016

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.
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Nature 529 (7584): 105-109. 7 January 2016


Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.
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Nature 528 (7581): 262-266. 10 December 2015

Crystal structure of the dynamin tetramer.
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Nature 525 (7569): 404-408. 17 September 2015

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation.
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Nature 520 (7546): 243-247. 9 April 2015

Fatty acid carbon is essential for dNTP synthesis in endothelial cells.
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Nature 520 (7546): 192-197. 9 April 2015

PLD3 in non-familial Alzheimer's disease.
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Nature 520 (7545): E3-E5. 2 April 2015


Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J. and Xie, G. and Singh, M. and Ghanbarian, A.T. and Raskó, T. and Szvetnik, A. and Cai, H. and Besser, D. and Prigione, A. and Fuchs, N.V. and Schumann, G.G. and Chen, W. and Lorincz, M.C. and Ivics, Z. and Hurst, L.D. and Izsvák, Z.
Nature 516 (7531): 405-409. 18 December 2014

Piezo2 is the major transducer of mechanical forces for touch sensation in mice.
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Nature 516 (7529): 121-125. 4 December 2014

Gibbon genome and the fast karyotype evolution of small apes.
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Nature 513 (7517): 195-201. 11 September 2014

Developmental biology: it takes muscle to make blood cells.
Sawamiphak, S. and Stainier, D.Y.R.
Nature 512 (7514): 257-258. 21 August 2014

Two independent transcription initiation codes overlap on vertebrate core promoters.
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Nature 507 (7492): 381-385. 20 March 2014

Bone biology: vessels of rejuvenation.
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Nature 507 (7492): 313-314. 20 March 2014


Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
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Nature 501 (7467): 421-425. 19 September 2013

M-CSF instructs myeloid lineage fate in single haematopoietic stem cells.
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Nature 497 (7448): 239-243. 9 May 2013

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.
Kleinewietfeld, M. and Manzel, A. and Titze, J. and Kvakan, H. and Yosef, N. and Linker, R.A. and Muller, D.N. and Hafler, D.A.
Nature 496 (7446): 518-522. 25 April 2013

Circular RNAs are a large class of animal RNAs with regulatory potency.
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Nature 495 (7441): 333-338. 21 March 2013

MicroRNA-34a regulates cardiac ageing and function.
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Nature 495 (7439): 107-110. 7 March 2013

Genomic variation landscape of the human gut microbiome.
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Nature 493 (7430): 45-50. 3 January 2013


FMRP targets distinct mRNA sequence elements to regulate protein expression.
Ascano, M. and Mukherjee, N. and Bandaru, P. and Miller, J.B. and Nusbaum, J.D. and Corcoran, D.L. and Langlois, C. and Munschauer, M. and Dewell, S. and Hafner, M. and Williams, Z. and Ohler, U. and Tuschl, T.
Nature 492 (7429): 382-386. 20 December 2012

Tissue engineering: Blood vessels on a chip.
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Nature 488 (7412): 465-466. 23 August 2012

The clonal and mutational evolution spectrum of primary triple-negative breast cancers.
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Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.
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Nature 486 (7402): 256-260. 29 April 2012

Deregulated MYC expression induces dependence upon AMPK-related kinase 5.
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Nature 483 (7391): 608-612. 29 March 2012


Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.
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Nature 478 (7367): 114-118. 6 October 2011

Deep sequencing reveals 50 novel genes for recessive cognitive disorders.
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Crystal structure of nucleotide-free dynamin.
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Stem cells: Orphan receptors find a home.
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Nature 476 (7360): 287-288. 18 August 2011

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.
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Nature 476 (7360): 298-303. 18 August 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
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Nature 476 (7359): 214-219. 10 August 2011

Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.
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Nature 474 (7352): 511-515. 23 June 2011

Global quantification of mammalian gene expression control.
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Nature 473 (7347): 337-342. 19 May 2011

Enterotypes of the human gut microbiome.
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Nature 473 (7346): 174-180. 12 May 2011

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase.
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Nature 473 (7346): 234-238. 12 May 2011


Gene expression divergence recapitulates the developmental hourglass model.
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Nature 468 (7325): 811-814. 9 December 2010

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.
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Nature 467 (7314): 460-464. 23 September 2010

Wnt11 patterns a myocardial electrical gradient through regulation of the L-type Ca(2+) channel.
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Loss of fish actinotrichia proteins and the fin-to-limb transition.
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Developmental sensory experience balances cortical excitation and inhibition.
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Nature 465 (7300): 932-936. 17 June 2010

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The genome of a songbird.
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Ancient animal microRNAs and the evolution of tissue identity.
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Nature 463 (7284): 1084-1088. 25 February 2010


Central control of fever and female body temperature by RANKL/RANK.
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Nature 462 (7272): 505-509. 26 November 2009

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Nature 462 (7269): 65-70. 5 November 2009

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
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Nature 459 (7249): 1000-1004. 18 June 2009

Clustering of InsP3 receptors by InsP3 retunes their regulation by InsP3 and Ca2+.
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Nature 458 (7238): 655-659. 2 April 2009

The ubiquitylation machinery of the endoplasmic reticulum.
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Nature 458 (7237): 453-460. 26 March 2009


The genome of the simian and human malaria parasite Plasmodium knowlesi.
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Nature 455 (7214): 799-803. 9 October 2008

Widespread changes in protein synthesis induced by microRNAs.
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Nature 454 (7206): 881-885. 14 August 2008

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The genome of the model beetle and pest tribolium castaneum.

Nature 452 (7190): 949-955. 24 April 2008

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.
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The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans.
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A viral microRNA functions as an orthologue of cellular miR-155.
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Nature 450 (7172): 1096-1099. 13 December 2007

Helicobacter exploits integrin for type IV secretion and kinase activation.
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Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling.
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Nature 449 (7164): 923-927. 3 October 2007

The menthol receptor TRPM8 is the principal detector of environmental cold.
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Neuroscience: The brain's garbage men.
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Nature 446 (7139): 987-989. 26 April 2007

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
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A stomatin-domain protein essential for touch sensation in the mouse.
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Spider toxins activate the capsaicin receptor to produce inflammatory pain.
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Insights into social insects from the genome of the honeybee Apis mellifera.

Nature 443 (7114): 931-949. 26 October 2006

Co-evolution of transcriptional and post-translational cell-cycle regulation.
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Hungary's 'reforms' are threatening basic science.
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Nature 443 (7110): 394. 28 September 2006

Proteome survey reveals modularity of the yeast cell machinery.
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Robust Salmonella metabolism limits possibilities for new antimicrobials.
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ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function.
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Nature 438 (7068): 685-689. 1 December 2005

Initial sequence of the chimpanzee genome and comparison with the human genome.
Mikkelsen, T.S. and Hillier, L.W. and Eichler, E.E. and Zody, M.C. and Jaffe, D.B. and Yang, S.P. and Enard, W. and Hellmann, I. and Lindblad-Toh, K. and Altheide, T.K. and Archidiacono, N. and Bork, P. and Butler, J. and Chang, J.L. and Cheng, Z. and Chinwalla, A.T. and de Jong, P. and Delehaunty, K.D. and Fronick, C.C. and Fulton, L.L. and Gilad, Y. and Glusman, G. and Gnerre, S. and Graves, T.A. and Hayakawa, T. and Hayden, K.E. and Huang, X.Q. and Ji, H.K. and Kent, W.J. and King, M.C. and Kulbokas, E.J. and Lee, M.K. and Liu, G. and Lopez-Otin, C. and Makova, K.D. and Man, O. and Mardis, E.R. and Mauceli, E. and Miner, T.L. and Nash, W.E. and Nelson, J.O. and Paeaebo, S. and Patterson, N.J. and Pohl, C.S. and Pollard, K.S. and Pruefer, K. and Puente, X.S. and Reich, D. and Rocchi, M. and Rosenbloom, K. and Ruvolo, M. and Richter, D.J. and Schaffner, S.F. and Smit, A.F.A. and Smith, S.M. and Suyama, M. and Taylor, J. and Torrents, D. and Tuzun, E. and Varki, A. and Velasco, G. and Ventura, M. and Wallis, J.W. and Wendl, M.C. and Wilson, R.K. and Lander, E.S. and Waterston, R.H.
Nature 437 (7055): 69-87. 1 September 2005

Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance.
Willimsky, G. and Blankenstein, T.
Nature 437 (7055): 141-146. 1 September 2005

Oncogene-induced senescence as an initial barrier in lymphoma development.
Braig, M. and Lee, S. and Loddenkemper, C. and Rudolph, C. and Peters, A.H. and Schlegelberger, B. and Stein, H. and Doerken, B. and Jenuwein, T. and Schmitt, C.A.
Nature 436 (7051): 660-665. 4 August 2005

Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins.
Scheel, O. and Zdebik, A.A. and Lourdel, S. and Jentsch, T.J.
Nature 436 (7049): 424-427. 21 July 2005

Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
Hillier, L.W. and Graves, T.A. and Fulton, R.S. and Fulton, L.A. and Pepin, K.H. and Minx, P. and Wagner-McPherson, C. and Layman, D. and Wylie, K. and Sekhon, M. and Becker, M.C. and Fewell, G.A. and Delehaunty, K.D. and Miner, T.L. and Nash, W.E. and Kremitzki, C. and Oddy, L. and Du, H. and Sun, H. and Bradshaw-Cordum, H. and Ali, J. and Carter, J. and Cordes, M. and Harris, A. and Isak, A. and van Brunt, A. and Nguyen, C. and Du, F. and Courtney, L. and Kalicki, J. and Ozersky, P. and Abbott, S. and Armstrong, J. and Belter, E.A. and Caruso, L. and Cedroni, M. and Cotton, M. and Davidson, T. and Desai, A. and Elliott, G. and Erb, T. and Fronick, C. and Gaige, T. and Haakenson, W. and Haglund, K. and Holmes, A. and Harkins, R. and Kim, K. and Kruchowski, S.S. and Strong, C.M. and Grewal, N. and Goyea, E. and Hou, S. and Levy, A. and Martinka, S. and Mead, K. and McLellan, M.D. and Meyer, R. and Randall-Maher, J. and Tomlinson, C. and uphin-Kohlberg, S. and Kozlowicz-Reilly, A. and Shah, N. and Swearengen-Shahid, S. and Snider, J. and Strong, J.T. and Thompson, J. and Yoakum, M. and Leonard, S. and Pearman, C. and Trani, L. and Radionenko, M. and Waligorski, J.E. and Wang, C. and Rock, S.M. and Tin-Wollam, A.M. and Maupin, R. and Latreille, P. and Wendl, M.C. and Yang, S.P. and Pohl, C. and Wallis, J.W. and Spieth, J. and Bieri, T.A. and Berkowicz, N. and Nelson, J.O. and Osborne, J. and Ding, L. and Meyer, R. and Sabo, A. and Shotland, Y. and Sinha, P. and Wohldmann, P.E. and Cook, L.L. and Hickenbotham, M.T. and Eldred, J. and Williams, D. and Jones, T.A. and She, X. and Ciccarelli, F.D. and Izaurralde, E. and Taylor, J. and Schmutz, J. and Myers, R.M. and Cox, D.R. and Huang, X. and McPherson, J.D. and Mardis, E.R. and Clifton, S.W. and Warren, W.C. and Chinwalla, A.T. and Eddy, S.R. and Marra, M.A. and Ovcharenko, I. and Furey, T.S. and Miller, W. and Eichler, E.E. and Bork, P. and Suyama, M. and Torrents, D. and Waterston, R.H. and Wilson, R.K.
Nature 434 : 724-731. 1 January 2005


Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.
Hillier, L.W. and Miller, W. and Birney, E. and Warren, W. and Hardison, R.C. and Ponting, C.P. and Bork, P. and Burt, D.W. and Groenen, M.A.M. and Delany, M.E. and Dodgson, J.B. and Chinwalla, A.T. and Cliften, P.F. and Clifton, S.W. and Delehaunty, K.D. and Fronick, C. and Fulton, R.S. and Graves, T.A. and Kremitzki, C. and Layman, D. and Magrini, V. and McPherson, J.D. and Miner, T.L. and Minx, P. and Nash, W.E. and Nhan, M.N. and Nelson, J.O. and Oddy, L.G. and Pohl, C.S. and Randall-Maher, J. and Smith, S.M. and Wallis, J.W. and Yang, S.P. and Romanov, M.N. and Rondelli, C.M. and Paton, B. and Smith, J. and Morrice, D. and Daniels, L. and Tempest, H.G. and Robertson, L. and Masabanda, J.S. and Griffin, D.K. and Vignal, A. and Fillon, V. and Jacobbson, L. and Kerje, S. and Andersson, L. and Crooijmans, R.P.M. and Aerts, J. and van der Poel, J.J. and Ellegren, H. and Caldwell, R.B. and Hubbard, S.J. and Grafham, D.V. and Kierzek, A.M. and McLaren, S.R. and Overton, I.M. and Arakawa, H. and Beattie, K.J. and Bezzubov, Y. and Boardman, P.E. and Bonfield, J.K. and Croning, M.D.R. and Davies, R.M. and Francis, M.D. and Humphray, S.J. and Scott, C.E. and Taylor, R.G. and Tickle, C. and Brown, W.R.A. and Rogers, J. and Buerstedde, J.M. and Wilson, S.A. and Stubbs, L. and Ovcharenko, I. and Gordon, L. and Lucas, S. and Miller, M.M. and Inoko, H. and Shiina, T. and Kaufman, J. and Salomonsen, J. and Skjoedt, K. and Wong, G.K.S. and Wang, J. and Liu, B. and Wang, J. and Yu, J. and Yang, H.M. and Nefedov, M. and Koriabine, M. and de Jong, P.J. and Goodstadt, L. and Webber, C. and Dickens, N.J. and Letunic, I. and Suyama, M. and Torrents, D. and von Mering, C. and Zdobnov, E.M. and Makova, K. and Nekrutenko, A. and Elnitski, L. and Eswara, P. and King, D.C. and Yang, S. and Tyekucheva, S. and Radakrishnan, A. and Harris, R.S. and Chiaromonte, F. and Taylor, J. and He, J.B. and Rijnkels, M. and Griffiths-Jones, S. and Ureta-Vidal, A. and Hoffman, M.M. and Severin, J. and Searle, S.M.J. and Law, A.S. and Speed, D. and Waddington, D. and Cheng, Z. and Tuzun, E. and Eichler, E. and Bao, Z.R. and Flicek, P. and Shteynberg, D.D. and Brent, M.R. and Bye, J.M. and Huckle, E.J. and Chatterji, S. and Dewey, C. and Pachter, L. and Kouranov, A. and Mourelatos, Z. and Hatzigeorgiou, A.G. and Paterson, A.H. and Ivarie, R. and Brandstrom, M. and Axelsson, E. and Backstrom, N. and Berlin, S. and Webster, M.T. and Pourquie, O. and Reymond, A. and Ucla, C. and Antonarakis, S.E. and Long, M.Y. and Emerson, J.J. and Betran, E. and Dupanloup, I. and Kaessmann, H. and Hinrichs, A.S. and Bejerano, G. and Furey, T.S. and Harte, R.A. and Raney, B. and Siepel, A. and Kent, W.J. and Haussler, D. and Eyras, E. and Castelo, R. and Abril, J.F. and Castellano, S. and Camara, F. and Parra, G. and Guigo, R. and Bourque, G. and Tesler, G. and Pevzner, P.A. and Smit, A. and Fulton, L.A. and Mardis, E.R. and Wilson, R.K.
Nature 432 (7018): 695-716. 9 December 2004

The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system.
Lu, X. and le Noble, F. and Yuan, L. and Jiang, Q. and de Lafarge, B. and Sugiyama, D. and Breant, C. and Claes, F. and de Smet, F. and Thomas, J.L. and Autiero, M. and Carmeliet, P. and Tessier-Lavigne, M. and Eichmann, A.
Nature 432 (7014): 179-186. 11 November 2004

A pancreatic islet-specific microRNA regulates insulin secretion.
Poy, M.N. and Eliasson, L. and Krutzfeldt, J. and Kuwajima, S. and Ma, X. and Macdonald, P.E. and Pfeffer, S. and Tuschl, T. and Rajewsky, N. and Rorsman, P. and Stoffel, M.
Nature 432 (7014): 226-230. 11 November 2004

Complex auditory behaviour emerges from simple reactive steering.
Hedwig, B. and Poulet, J.F.A.
Nature 430 (7001): 781-785. 12 August 2004

Cadherin 23 is a component of the tip link in hair-cell stereocilia.
Siemens, J. and Lillo, C. and Dumont, R.A. and Reynolds, A. and Williams, D.S. and Gillespie, P.G. and Mueller, U.
Nature 428 (6986): 950-955. 29 April 2004

Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells.
Soellner, C. and Rauch, G.J. and Siemens, J. and Geisler, R. and Schuster, S.C. and Mueller, U. and Nicolson, T.
Nature 428 (6986): 955-959. 29 April 2004

Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs, R.A. and Weinstock, G.M. and Metzker, M.L. and Muzny, D.M. and Sodergren, E.J. and Scherer, S. and Scott, G. and Steffen, D. and Worley, K.C. and Burch, P.E. and Okwuonu, G. and Hines, S. and Lewis, L. and DeRamo, C. and Delgado, O. and Dugan-Rocha, S. and Miner, G. and Morgan, M. and Hawes, A. and Gill, R. and Holt, R.A. and Adams, M.D. and Amanatides, P.G. and Baden-Tillson, H. and Barnstead, M. and Chin, S. and Evans, C.A. and Ferriera, S. and Fosler, C. and Glodek, A. and Gu, Z. and Jennings, D. and Kraft, C.L. and Nguyen, T. and Pfannkoch, C.M. and Sitter, C. and Sutton, G.G. and Venter, J.C. and Woodage, T. and Smith, D. and Lee, H.M. and Gustafson, E. and Cahill, P. and Kana, A. and Doucette-Stamm, L. and Weinstock, K. and Fechtel, K. and Weiss, R.B. and Dunn, D.M. and Green, E.D. and Blakesley, R.W. and Bouffard, G.G. and de Jong, P.J. and Osoegawa, K. and Zhu, B. and Marra, M. and Schein, J. and Bosdet, I. and Fjell, C. and Jones, S. and Krzywinski, M. and Mathewson, C. and Siddiqui, A. and Wye, N. and McPherson, J. and Zhao, S. and Fraser, C.M. and Shetty, J. and Shatsman, S. and Geer, K. and Chen, Y. and Abramzon, S. and Nierman, W.C. and Havlak, P.H. and Chen, R. and Durbin, K.J. and Egan, A. and Ren, Y. and Song, X.Z. and Li, B. and Liu, Y. and Qin, X. and Cawley, S. and Worley, K.C. and Cooney, A.J. and D'Souza, L.M. and Martin, K. and Wu, J.Q. and Gonzalez-Garay, M.L. and Jackson, A.R. and Kalafus, K.J. and McLeod, M.P. and Milosavljevic, A. and Virk, D. and Volkov, A. and Wheeler, D.A. and Zhang, Z. and Bailey, J.A. and Eichler, E.E. and Tuzun, E. and Birney, E. and Mongin, E. and Ureta-Vidal, A. and Woodwark, C. and Zdobnov, E. and Bork, P. and Suyama, M. and Torrents, D. and Alexandersson, M. and Trask, B.J. and Young, J.M. and Huang, H. and Wang, H. and Xing, H. and Daniels, S. and Gietzen, D. and Schmidt, J. and Stevens, K. and Vitt, U. and Wingrove, J. and Camara, F. and Alba, M.M. and Abril, J.F. and Guigo, R. and Smit, A. and Dubchak, I. and Rubin, E.M. and Couronne, O. and Poliakov, A. and Huebner, N. and Ganten, D. and Goesele, C. and Hummel, O. and Kreitler, T. and Lee, Y.A. and Monti, J. and Schulz, H. and Zimdahl, H. and Himmelbauer, H. and Lehrach, H. and Jacob, H.J. and Bromberg, S. and Gullings-Handley, J. and Jensen-Seaman, M.I. and Kwitek, A.E. and Lazar, J. and Pasko, D. and Tonellato, P.J. and Twigger, S. and Ponting, C.P. and Duarte, J.M. and Rice, S. and Goodstadt, L. and Beatson, S.A. and Emes, R.D. and Winter, E.E. and Webber, C. and Brandt, P. and Nyakatura, G. and Adetobi, M. and Chiaromonte, F. and Elnitski, L. and Eswara, P. and Hardison, R.C. and Hou, M. and Kolbe, D. and Makova, K. and Miller, W. and Nekrutenko, A. and Riemer, C. and Schwartz, S. and Taylor, J. and Yang, S. and Zhang, Y. and Lindpaintner, K. and Andrews, T.D. and Caccamo, M. and Clamp, M. and Clarke, L. and Curwen, V. and Durbin, R. and Eyras, E. and Searle, S.M. and Cooper, G.M. and Batzoglou, S. and Brudno, M. and Sidow, A. and Stone, E.A. and Venter, J.C. and Payseur, B.A. and Bourque, G. and Lopez-Otin, C. and Puente, X.S. and Chakrabarti, K. and Chatterji, S. and Dewey, C. and Pachter, L. and Bray, N. and Yap, V.B. and Caspi, A. and Tesler, G. and Pevzner, P.A. and Haussler, D. and Roskin, K.M. and Baertsch, R. and Clawson, H. and Furey, T.S. and Hinrichs, A.S. and Karolchik, D. and Kent, W.J. and Rosenbloom, K.R. and Trumbower, H. and Weirauch, M. and Cooper, D.N. and Stenson, P.D. and Ma, B. and Brent, M. and Arumugam, M. and Shteynberg, D. and Copley, R.R. and Taylor, M.S. and Riethman, H. and Mudunuri, U. and Peterson, J. and Guyer, M. and Felsenfeld, A. and Old, S. and Mockrin, S. and Collins, F.
Nature 428 (6982): 493-521. 1 April 2004

Sortilin is essential for proNGF-induced neuronal cell death.
Nykjaer, A. and Lee, R. and Teng, K.K. and Jansen, P. and Madsen, P. and Nielsen, M.S. and Jacobsen, C. and Kliemannel, M. and Schwarz, E. and Willnow, T.E. and Hempstead, B.L. and Petersen, C.M.
Nature 427 (6977): 843-848. 26 February 2004


Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion.
Prinz, M. and Heikenwalder, M. and Junt, T. and Schwarz, P. and Glatzel, M. and Heppner, F.L. and Fu, Y.X. and Lipp, M. and Aguzzi, A.
Nature 425 (6961): 957-962. 30 October 2003

The DNA sequence of human chromosome 7.
Hillier, L.W. and Fulton, R.S. and Fulton, L.A. and Graves, T.A. and Pepin, K.H. and Wagner-McPherson, C. and Layman, D. and Maas, J. and Jaeger, S. and Walker, R. and Wylie, K. and Sekhon, M. and Becker, M.C. and O'Laughlin, M.D. and Schaller, M.E. and Fewell, G.A. and Delehaunty, K.D. and Miner, T.L. and Nash, W.E. and Cordes, M. and Du, H. and Sun, H. and Edwards, J. and Bradshaw-Cordum, H. and Ali, J. and Andrews, S. and Isak, A. and VanBrunt, A. and Nguyen, C. and Du, F.Y. and Lamar, B. and Courtney, L. and Kalicki, J. and Ozersky, P. and Bielicki, L. and Scott, K. and Holmes, A. and Harkins, R. and Harris, A. and Strong, C.M. and Hou, S.F. and Tomlinson, C. and Dauphin-Kohlberg, S. and Kozlowicz-Reilly, A. and Leonard, S. and Rohlfing, T. and Rock, S.M. and Tin-Wollam, A.M. and Abbott, A. and Minx, P. and Maupin, R. and Strowmatt, C. and Latreille, P. and Miller, N. and Johnson, D. and Murray, J. and Woessner, J.P. and Wendl, M.C. and Yang, S.P. and Schultz, B.R. and Wallis, J.W. and Spieth, J. and Bieri, T.A. and Nelson, J.O. and Berkowicz, N. and Wohldmann, P.E. and Cook, L.L. and Hickenbotham, M.T. and Eldred, J. and Williams, D. and Bedell, J.A. and Mardis, E.R. and Clifton, S.W. and Chissoe, S.L. and Marra, M.A. and Raymond, C. and Haugen, E. and Gillett, W. and Zhou, Y. and James, R. and Phelps, K. and Iadanoto, S. and Bubb, K. and Simms, E. and Levy, R. and Clendenning, J. and Kaul, R. and Kent, W.J. and Furey, T.S. and Baertsch, R.A. and Brent, M.R. and Keibler, E. and Flicek, P. and Bork, P. and Suyama, M. and Bailey, J.A. and Portnoy, M.E. and Torrents, D. and Chinwalla, A.T. and Gish, W.R. and Eddy, S.R. and McPherson, J.D. and Olson, M.V. and Eichler, E.E. and Green, E.D. and Waterston, R.H. and Wilson, R.K.
Nature 424 : 157-164. 1 January 2003


Initial sequencing and comparative analysis of the mouse genome.
Waterston, R.H. and Lindblad-Toh, K. and Birney, E. and Rogers, J. and Abril, J.F. and Agarwal, P. and Agarwala, R. and Ainscough, R. and Alexandersson, M. and An, P. and Antonarakis, S.E. and Attwood, J. and Baertsch, R. and Bailey, J. and Barlow, K. and Beck, S. and Berry, E. and Birren, B. and Bloom, T. and Bork, P. and Botcherby, M. and Bray, N. and Brent, M.R. and Brown, D.G. and Brown, S.D. and Bult, C. and Burton, J. and Butler, J. and Campbell, R.D. and Carninci, P. and Cawley, S. and Chiaromonte, F. and Chinwalla, A.T. and Church, D.M. and Clamp, M. and Clee, C. and Collins, F.S. and Cook, L.L. and Copley, R.R. and Coulson, A. and Couronne, O. and Cuff, J. and Curwen, V. and Cutts, T. and Daly, M. and David, R. and Davies, J. and Delehaunty, K.D. and Deri, J. and Dermitzakis, E.T. and Dewey, C. and Dickens, N.J. and Diekhans, M. and Dodge, S. and Dubchak, I. and Dunn, D.M. and Eddy, S.R. and Elnitski, L. and Emes, R.D. and Eswara, P. and Eyras, E. and Felsenfeld, A. and Fewell, G.A. and Flicek, P. and Foley, K. and Frankel, W.N. and Fulton, L.A. and Fulton, R.S. and Furey, T.S. and Gage, D. and Gibbs, R.A. and Glusman, G. and Gnerre, S. and Goldman, N. and Goodstadt, L. and Grafham, D. and Graves, T.A. and Green, E.D. and Gregory, S. and Guigo, R. and Guyer, M. and Hardison, R.C. and Haussler, D. and Hayashizaki, Y. and Hillier, L.W. and Hinrichs, A. and Hlavina, W. and Holzer, T. and Hsu, F. and Hua, A. and Hubbard, T. and Hunt, A. and Jackson, I. and Jaffe, D.B. and Johnson, L.S. and Jones, M. and Jones, T.A. and Joy, A. and Kamal, M. and Karlsson, E.K. and Karolchik, D. and Kasprzyk, A. and Kawai, J. and Keibler, E. and Kells, C. and Kent, W.J. and Kirby, A. and Kolbe, D.L. and Korf, I. and Kucherlapati, R.S. and Kulbokas, E.J. and Kulp, D. and Landers, T. and Leger, J.P. and Leonard, S. and Letunic, I. and LeVine, R. and Li, J. and Li, M. and Lloyd, C. and Lucas, S. and Ma, B. and Maglott, D.R. and Mardis, E.R. and Matthews, L. and Mauceli, E. and Mayer, J.H. and McCarthy, M. and McCombie, W.R. and McLaren, S. and McLay, K. and McPherson, J.D. and Meldrim, J. and Meredith, B. and Mesirov, J.P. and Miller, W. and Miner, T.L. and Mongin, E. and Montgomery, K.T. and Morgan, M. and Mott, R. and Mullikin, J.C. and Muzny, D.M. and Nash, W.E. and Nelson, J.O. and Nhan, M.N. and Nicol, R. and Ning, Z. and Nusbaum, C. and O'Connor, M.J. and Okazaki, Y. and Oliver, K. and Overton-Larty, E. and Pachter, L. and Parra, G. and Pepin, K.H. and Peterson, J. and Pevzner, P. and Plumb, R. and Pohl, C.S. and Poliakov, A. and Ponce, T.C. and Ponting, C.P. and Potter, S. and Quail, M. and Reymond, A. and Roe, B.A. and Roskin, K.M. and Rubin, E.M. and Rust, A.G. and Santos, R. and Sapojnikov, V. and Schultz, B. and Schultz, J. and Schwartz, M.S. and Schwartz, S. and Scott, C. and Seaman, S. and Searle, S. and Sharpe, T. and Sheridan, A. and Shownkeen, R. and Sims, S. and Singer, J.B. and Slater, G. and Smit, A. and Smith, D.R. and Spencer, B. and Stabenau, A. and Stange-Thomann, N. and Sugnet, C. and Suyama, M. and Tesler, G. and Thompson, J. and Torrents, D. and Trevaskis, E. and Tromp, J. and Ucla, C. and Ureta-Vidal, A. and Vinson, J.P. and von Niederhausern, A.C. and Wade, C.M. and Wall, M. and Weber, R.J. and Weiss, R.B. and Wendl, M.C. and West, A.P. and Wetterstrand, K. and Wheeler, R. and Whelan, S. and Wierzbowski, J. and Willey, D. and Williams, S. and Wilson, R.K. and Winter, E. and Worley, K.C. and Wyman, D. and Yang, S. and Yang, S.P. and Zdobnov, E.M. and Zody, M.C. and Lander, E.S.
Nature 420 (6915): 520-562. 5 December 2002

Metabolic network structure determines key aspects of functionality and regulation.
Stelling, J. and Klamt, S. and Bettenbrock, K. and Schuster, S. and Gilles, E.D.
Nature 420 (6912): 190-193. 14 November 2002

A corollary discharge maintains auditory sensitivity during sound production.
Poulet, J.F.A. and Hedwig, B.
Nature 418 (6900): 872-876. 22 August 2002

Genome organization: Teamed up for transcription.
von Mering, C. and Bork, P.
Nature 417 (6891): 797-798. 20 June 2002

Comparative assessment of large-scale data sets of protein-protein interactions.
von Mering, C. and Krause, R. and Snel, B. and Cornell, M. and Oliver, S.G. and Fields, S. and Bork, P.
Nature 417 (6887): 399-403. 23 May 2002

Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter Kcc4.
Boettger, T. and Huebner, C.A. and Maier, H. and Rust, M.B. and Beck, F.X. and Jentsch, T.J.
Nature 416 (6883): 874-878. 25 April 2002

Chloride channels are different.
Jentsch, T.J.
Nature 415 (6869): 276-277. 17 January 2002

Functional organization of the yeast proteome by systematic analysis of protein complexes.
Gavin, A.C. and Boesche, M. and Krause, R. and Grandi, P. and Marzioch, M. and Bauer, A. and Schultz, J. and Rick, J.M. and Michon, A.M. and Cruciat, C.M. and Remor, M. and Hoefert, C. and Schelder, M. and Brajenovic, M. and Ruffner, H. and Merino, A. and Klein, K. and Hudak, M. and Dickson, D. and Rudi, T. and Gnau, V. and Bauch, A. and Bastuck, S. and Huhse, B. and Leutwein, C. and Heurtier, M.A. and Copley, R.R. and Edelmann, A. and Querfurth, E. and Rybin, V. and Drewes, G. and Raida, M. and Bouwmeester, T. and Bork, P. and Seraphin, B. and Kuester, B. and Neubauer, G. and Superti-Furga, G.
Nature 415 (6868): 141-147. 10 January 2002

Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position.
Reif, K. and Ekland, E.H. and Ohl, L. and Nakano, H. and Lipp, M. and Foerster, R. and Cyster, J.G.
Nature 416 : 94-99. 1 January 2002


Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.
Estevez, R. and Boettger, T. and Stein, V. and Birkenhaeger, R. and Otto, E. and Hildebrandt, F. and Jentsch, T.J.
Nature 414 (6863): 558-561. 29 November 2001

Planned law could put German research at risk.
Jentsch, T.
Nature 413 (6858): 772. 25 October 2001

Hero or villain? Stasi archives shed light on russian scientist.
Hossfeld, U. and Walker, M.
Nature 411 (6835): 237. 17 May 2001

Skewed maturation of memory HIV-specific CD8 T lymphocytes.
Champagne, P. and Ogg, G.S. and King, A.S. and Knabenhans, C. and Ellefsen, K. and Nobile, M. and Appay, V. and Rizzardi, G.P. and Fleury, S. and Lipp, M. and Foerster, R. and Rowland-Jones, S. and Sekaly, R.P. and McMichael, A.J. and Pantaleo, G.
Nature 410 (6824): 106-111. 1 March 2001

The draft sequences. Filling in the gaps.
Bork, P. and Copley, R.
Nature 409 (6822): 818-820. 15 February 2001

Initial sequencing and analysis of the human genome.
Lander, E.S. and Linton, L.M. and Birren, B. and Nusbaum, C. and Zody, M.C. and Baldwin, J. and Devon, K. and Dewar, K. and Doyle, M. and FitzHugh, W. and Funke, R. and Gage, D. and Harris, K. and Heaford, A. and Howland, J. and Kann, L. and Lehoczky, J. and LeVine, R. and McEwan, P. and McKernan, K. and Meldrim, J. and Mesirov, J.P. and Miranda, C. and Morris, W. and Naylor, J. and Raymond, C. and Rosetti, M. and Santos, R. and Sheridan, A. and Sougnez, C. and Stange-Thomann, N. and Stojanovic, N. and Subramanian, A. and Wyman, D. and Rogers, J. and Sulston, J. and Ainscough, R. and Beck, S. and Bentley, D. and Burton, J. and Clee, C. and Carter, N. and Coulson, A. and Deadman, R. and Deloukas, P. and Dunham, A. and Dunham, I. and Durbin, R. and French, L. and Grafham, D. and Gregory, S. and Hubbard, T. and Humphray, S. and Hunt, A. and Jones, M. and Lloyd, C. and McMurray, A. and Matthews, L. and Mercer, S. and Milne, S. and Mullikin, J.C. and Mungall, A. and Plumb, R. and Ross, M. and Shownkeen, R. and Sims, S. and Waterston, R.H. and Wilson, R.K. and Hillier, L.W. and McPherson, J.D. and Marra, M.A. and Mardis, E.R. and Fulton, L.A. and Chinwalla, A.T. and Pepin, K.H. and Gish, W.R. and Chissoe, S.L. and Wendl, M.C. and Delehaunty, K.D. and Miner, T.L. and Delehaunty, A. and Kramer, J.B. and Cook, L.L. and Fulton, R.S. and Johnson, D.L. and Minx, P.J. and Clifton, S.W. and Hawkins, T. and Branscomb, E. and Predki, P. and Richardson, P. and Wenning, S. and Slezak, T. and Doggett, N. and Cheng, J.F. and Olsen, A. and Lucas, S. and Elkin, C. and Uberbacher, E. and Frazier, M. and Gibbs, R.A. and Muzny, D.M. and Scherer, S.E. and Bouck, J.B. and Sodergren, E.J. and Worley, K.C. and Rives, C.M. and Gorrell, J.H. and Metzker, M.L. and Naylor, S.L. and Kucherlapati, R.S. and Nelson, D.L. and Weinstock, G.M. and Sakaki, Y. and Fujiyama, A. and Hattori, M. and Yada, T. and Toyoda, A. and Itoh, T. and Kawagoe, C. and Watanabe, H. and Totoki, Y. and Taylor, T. and Weissenbach, J. and Heilig, R. and Saurin, W. and Artiguenave, F. and Brottier, P. and Bruls, T. and Pelletier, E. and Robert, C. and Wincker, P. and Rosenthal, A. and Platzer, M. and Nyakatura, G. and Taudien, S. and Rump, A. and Yang, H.M. and Yu, J. and Wang, J. and Huang, G.Y. and Gu, J. and Hood, L. and Rowen, L. and Madan, A. and Qin, S.Z. and Davis, R.W. and Federspiel, N.A. and Abola, A.P. and Proctor, M.J. and Myers, R.M. and Schmutz, J. and Dickson, M. and Grimwood, J. and Cox, D.R. and Olson, M.V.
Nature 409 (6822): 860-921. 15 February 2001

Genome speak.
Bork, P. and Copley, R.
Nature 409 : 815. 1 January 2001


Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III.
Gonczy, P. and Echeverri, G. and Oegema, K. and Coulson, A. and Jones, S.J. and Copley, R.R. and Duperon, J. and Oegema, J. and Brehm, M. and Cassin, E. and Hannak, E. and Kirkham, M. and Pichler, S. and Flohrs, K. and Goessen, A. and Leidel, S. and Alleaume, A.M. and Martin, C. and Ozlu, N. and Bork, P. and Hyman, A.A.
Nature 408 (6810): 331-336. 16 November 2000

ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease.
Piwon, N. and Guenther, W. and Schwake, M. and Boesl, M.R. and Jentsch, T.J.
Nature 408 (6810): 369-373. 16 November 2000

The mammalian sodium channel BNC1 is required for normal touch sensation.
Price, M.P. and Lewin, G.R. and McIlwrath, S.L. and Cheng, C. and Xie, J.H. and Heppenstall, P.A. and Stucky, C.L. and Mannsfeldt, A.G. and Brennan, T.J. and Drummond, H.A. and Qiao, J. and Benson, C.J. and Tarr, D.E. and Hrstka, R.F. and Yang, B.L. and Williamson, R.A. and Welsh, M.J.
Nature 407 (6807): 1007-1011. 26 October 2000

Kainate receptors and synaptic plasticity.
Nicoll, R.A. and Mellor, J. and Frerking, M. and Schmitz, D.
Nature 406 (6799): 957. 31 August 2000

A chemokine-driven positive feedback loop organizes lymphoid follicles.
Ansel, K.M. and Ngo, V.N. and Hyman, P.L. and Luther, S.A. and Foerster, R. and Sedgwick, J.D. and Browning, J.L. and Lipp, M. and Cyster, J.G.
Nature 406 (6793): 309-314. 20 July 2000

A function for dysfunction - Ion channels and disease.
Jentsch, T.J.
Nature 406 (6793): 236-237. 20 July 2000

Distinguished scientists back Germany's DFG . .
Jahn, R. and Boeck, A. and Breiner, K.M. and Breunig, K.D. and Bujard, H. and Campos-Ortega, J. and Ganten, D. and Grummt, I. and Gruss, P. and Goridis, C. and Huber, R. and Hoch, M. and Jaeckle, H. and Kahmann, R. and Koch-Brandt, C. and Leptin, M. and Michel, H. and Noegel, A. and Neher, E. and Nuesslein-Volhard, C. and Pfanner, N. and Sandhoff, K. and Schoen, A. and Schwille, P. and Simons, K. and Zrenner, E.
Nature 404 : 922-922. 27 April 2000

A constitutively open potassium channel formed by KCNQ1 and KCNE3.
Schroeder, B.C. and Waldegger, S. and Fehr, S. and Bleich, M. and Warth, R. and Greger, R. and Jentsch, T.J.
Nature 403 (6766): 196-199. 13 January 2000


Two subsets of memory T lymphocytes with distinct homing potentials and effector functions.
Sallusto, F. and Lenig, D. and Foerster, R. and Lipp, M. and Lanzavecchia, A.
Nature 401 (6754): 708-712. 14 October 1999

Cytochrome P450 2C is an EDHF synthase in coronary arteries.
Fisslthaler, B. and Popp, R. and Kiss, L. and Potente, M. and Harder, D.R. and Fleming, I. and Busse, R.
Nature 401 (6752): 493-497. 30 September 1999

Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP.
Yeung, K. and Seitz, T. and Li, S.F. and Janosch, P. and McFerran, B. and Kaiser, C. and Fee, F. and Katsanakis, K.D. and Rose, D.W. and Mischak, H. and Sedivy, J.M. and Kolch, W.
Nature 401 (6749): 173-177. 9 September 1999

The mahogany protein is a receptor involved in suppression of obesity.
Nagle, D.L. and McGrail, S.H. and Vitale, J. and Wolf, E.A. and Dussault, B.J. and DiRocco, L. and Holmgren, L. and Montagno, J. and Bork, P. and Huszar, D. and Fairchild-Huntress, V. and Ge, P. and Keilty, J. and Ebeling, C. and Baldini, L. and Gilchrist, J. and Burn, P. and Carlson, G.A. and Moore, K.J.
Nature 398 : 148-152. 11 March 1999

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28.
Hutloff, A. and Dittrich, A.M. and Beier, K.C. and Eljaschewitsch, B. and Kraft, R. and Anagnostopoulos, I. and Kroczek, R.A.
Nature 397 (6716): 263-266. 21 January 1999


Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy.
Schroeder, B.C. and Kubisch, C. and Stein, V. and Jentsch, T.J.
Nature 396 (6712): 687-690. 17 December 1998

Signal transduction. Docking IkappaB kinases.
Scheidereit, C.
Nature 395 : 225-226. 17 September 1998

Csk controls antigen receptor-mediated development and selection of T-lineage cells.
Schmedt, C. and Saijo, K. and Niidome, T. and Kuehn, R. and Aizawa, S. and Tarakhovsky, A.
Nature 394 (6696): 901-904. 27 August 1998

Microdomains of GPI-anchored proteins in living cells revealed by crosslinking.
Friedrichson, T. and Kurzchalia, T.V.
Nature 394 (6695): 802-805. 20 August 1998

Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro.
Draguhn, A. and Traub, R.D. and Schmitz, D. and Jefferys, J.G.R.
Nature 394 (6689): 189-192. 9 July 1998

CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells.
Henn, V. and Slupsky, J.R. and Graefe, M. and Anagnostopoulos, I. and Foerster, R. and Mueller-Berghaus, G. and Kroczek, R.A.
Nature 391 (667): 591-594. 1 January 1998


Severe neuropathies in mice with targeted mutations in the ErbB3 receptor.
Riethmacher, D. and Sonnenberg-Riethmacher, E. and Brinkmann, V. and Yamaai, T. and Lewin, G.R. and Birchmeier, C.
Nature 389 (6652): 725-730. 16 October 1997

More hippocampal neurons in adult mice living in an enriched environment.
Kempermann, G. and Kuhn, H.G. and Gage, F.H.
Nature 386 (6624): 493-495. 3 April 1997

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation.
Plemper, R.K. and Bohmler, S. and Bordallo, J. and Sommer, T. and Wolf, D.H.
Nature 388 : 891-895. 1 January 1997


Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
Weidner, K.M. and Dicesare, S. and Sachs, M. and Brinkmann, V. and Behrens, J. and Birchmeier, W.
Nature 384 (6605): 173-176. 14 November 1996

Two physically distinct pores in the dimeric ClC-0 chloride channel.
Ludewig, U. and Pusch, M. and Jentsch, T.J.
Nature 383 (6598): 340-343. 26 September 1996

The C5a chemoattractant receptor mediates mucosal defence to infection.
Höpken, U.E. and Lu, B. and Gerard, N.P. and Gerard, C.
Nature 383 (6595): 86-89. 5 September 1996

Functional interaction of beta-catenin with the transcription factor LEF-1.
Behrens, J. and von Kries, J.P. and Kuehl, M. and Bruhn, L. and Wedlich, D. and Grosschedl, R. and Birchmeier, W.
Nature 382 (6592): 638-642. 15 August 1996

A common molecular basis for three inherited kidney stone diseases.
Lloyd, S.E. and Pearce, S.H. and Fisher, S.E. and Steinmeyer, K. and Schwappach, B. and Scheinman, S.J. and Harding, B. and Bolino, A. and Devoto, M. and Goodyer, P. and Rigden, S.P. and Wrong, O. and Jentsch, T.J. and Craig, I.W. and Thakker, R.V.
Nature 379 (6564): 445-449. 1 February 1996

Requirement of mammalian DNA polymerase-beta in base-excision repair.
Sobol, R.W. and Horton, J.K. and Kühn, R. and Gu, H. and Singhal, R.K. and Prasad, R. and Rajewsky, K. and Wilson, S.H.
Nature 379 (6561): 183-186. 11 January 1996

Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein.
Brocke, S. and Gijbels, K. and Allegretta, M. and Ferber, I. and Piercy, C. and Blankenstein, T. and Martin, R. and Utz, U. and Karin, N. and Mitchell, D. and Veromaa, T. and Waisman, A. and Gaur, A. and Conlon, P. and Ling, N. and Fairchild, P.J. and Wraith, D.C. and Ogarra, A. and Fathman, C.G. and Steinman, L.
Nature 379 (6563): 343-346. 1 January 1996


Multiple essential functions of neuregulin in development.
Meyer, D. and Birchmeier, C.
Nature 378 (6555): 386-390. 23 November 1995

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud.
Bladt, F. and Riethmacher, D. and Isenmann, S. and Aguzzi, A. and Birchmeier, C.
Nature 376 (6543): 768-771. 31 August 1995

Scatter factor/hepatocyte growth factor is essential for liver development.
Schmidt, C. and Bladt, F. and Goedecke, S. and Brinkmann, V. and Zschiesche, W. and Sharpe, M. and Gherardi, E. and Birchmeier, C.
Nature 373 (6515): 699-702. 23 February 1995

Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion.
Pusch, M. and Ludewig, U. and Rehfeldt, A. and Jentsch, T.J.
Nature 373 (6514): 527-531. 9 February 1995

Challenging times for bioinformatics.
Casari, G. and Andrade, M.A. and Bork, P. and Daruvar, A. and Ouzounis, C. and Schneider, R. and Tamames, J. and Valencia, A. and Sander, C.
Nature 376 : 647-648. 1 January 1995

Distinct functions for the two importin subunits in nuclear protein import.
Goerlich, D. and Vogel, F. and Mills, A.D. and Hartmann, E. and Laskey, R.A.
Nature 377 : 246-248. 1 January 1995


Implications for dorsoventral axis determination from the zebrafish mutation janus.
Abdelilah, S. and Solnica-Krezel, L. and Stainier, D.Y. and Driever, W.
Nature 370 (6489): 468-471. 11 August 1994

NMDA receptors and activity-dependent tuning of the receptive fields of spinal cord neurons.
Lewin, G.R. and Mckintosh, E. and McMahon, S.B.
Nature 369 (6480): 482-485. 9 June 1994

Trinity of cation channels.
Jentsch, T.J.
Nature 367 (6462): 412-413. 3 February 1994

Evolutionary conservation of components of the protein translocation complex.
Hartmann, E. and Sommer, T. and Prehn, S. and Goerlich, D. and Jentsch, S. and Rapoport, T.A.
Nature 367 : 654-657. 1 January 1994


Universal nucleic acid-binding domain revealed by crystal structure of the B. subtilis major cold-shock protein.
Schindelin, H. and Marahiel, M.A. and Heinemann, U.
Nature 364 (6433): 164-168. 8 July 1993

Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis.
Bommert, K. and Charlton, M.P. and DeBello, W.M. and Chin, G.J. and Betz, H. and Augustine, G.J.
Nature 363 (6425): 163-165. 13 May 1993

A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice.
Schedl, A. and Montoliu, L. and Kelsey, G. and Schutz, G.
Nature 362 (6417): 258-261. 18 March 1993

Qa-2 molecules are peptide receptors of higher stringency than ordinary class I molecules.
Roetzschke, O. and Falk, K. and Stevanovic, S. and Grahovac, B. and Soloski, M.J. and Jung, G. and Rammensee, H.G.
Nature 361 (6413): 642-644. 18 February 1993

Benzodiazepine-induced motor impairment linked to point mutation in cerebellar GABAA receptor.
Korpi, E.R. and Kleingoor, C. and Kettenmann, H. and Seeburg, P.H.
Nature 361 : 356-359. 1 January 1993

A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum.
Sommer, T. and Jentsch, S.
Nature 365 : 176-179. 1 January 1993


Regions involved in the opening of CIC-2 chloride channel by voltage and cell volume.
Gruender, S. and Thiemann, A. and Pusch, M. and Jentsch, T.J.
Nature 360 (6406): 759-762. 24 December 1992

Molecular identification of the gene responsible for congenital nephrogenic diabetes insipidus.
Rosenthal, W. and Seibold, A. and Antaramian, A. and Lonergan, M. and Arthus, M.F. and Hendy, G.N. and Birnbaumer, M. and Bichet, D.G.
Nature 359 (6392): 233-235. 17 September 1992

Molecular cloning of the receptor for human antidiuretic hormone.
Birnbaumer, M. and Seibold, A. and Gilbert, S. and Ishido, M. and Barberis, C. and Antaramian, A. and Brabet, P. and Rosenthal, W.
Nature 357 (6376): 333-335. 28 May 1992

A chloride channel widely expressed in epithelial and non-epithelial cells.
Thiemann, A. and Gruender, S. and Pusch, M. and Jentsch, T.J.
Nature 356 (6364): 57-60. 5 March 1992

What's in a genome?
Bork, P. and Ouzounis, C. and Sander, C. and Scharf, M. and Schneider, R. and Sonnhammer, E.
Nature 358 : 287. 1 January 1992

A protein of the endoplasmic reticulum involved early in polypeptide translocation.
Goerlich, D. and Hartmann, E. and Prehn, S. and Rapoport, T.A.
Nature 357 : 47-52. 1 January 1992

Signal sequence identified.
Hartmann, E. and Rapoport, T.A. and Prehn, S.
Nature 358 : 198. 1 January 1992

Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappaB.
Wulczyn, F.G. and Naumann, M. and Scheidereit, C.
Nature 358 (6387): 597-599. 1 January 1992


Inactivation of muscle chloride channel by transposon insertion in myotonic mice.
Steinmeyer, K. and Klocke, R. and Ortland, C. and Gronemeier, M. and Jockusch, H. and Gruender, S. and Jentsch, T.J.
Nature 354 (6351): 304-308. 28 November 1991

Primary structure and functional expression of a developmentally regulated skeletal muscle chloride channel.
Steinmeyer, K. and Ortland, C. and Jentsch, T.J.
Nature 354 (6351): 301-304. 28 November 1991

Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats.
Hilbert, P. and Lindpaintner, K. and Beckmann, J.S. and Serikawa, T. and Soubrier, F. and Dubay, C.J. and Cartwright, P. and De Gouyon, B. and Julier, C. and Takahashi, S. and Vincent, M. and Ganten, D. and Georges, M. and Lathrop, G.M.
Nature 353 (6344): 521-529. 10 October 1991

Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents.
Kleuss, C. and Hescheler, J. and Ewel, C. and Rosenthal, W. and Schultz, G. and Wittig, B.
Nature 353 (6339): 43-48. 5 September 1991

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene.
Kitamura, D. and Roes, J. and Kühn, R. and Rajewsky, K.
Nature 350 (6317): 423-426. 4 April 1991

Protein translocation. A bacterium catches up.
Rapoport, T.A.
Nature 349 : 107-108. 1 January 1991


Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes.
Jentsch, T.J. and Steinmeyer, K. and Schwarz, G.
Nature 348 (6301): 510-514. 6 December 1990


The GTP-binding protein, Go, regulates neuronal calcium channels.
Hescheler, J. and Rosenthal, W. and Trautwein, W. and Schultz, G.
Nature 325 (6103): 445-447. 29 January 1987

This list was generated on Mon Oct 25 02:29:34 2021 CEST.
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