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Structure and function of the global topsoil microbiome.
Bahram, M. and Hildebrand, F. and Forslund, S.K. and Anderson, J.L. and Soudzilovskaia, N.A. and Bodegom, P.M. and Bengtsson-Palme, J. and Anslan, S. and Coelho, L.P. and Harend, H. and Huerta-Cepas, J. and Medema, M.H. and Maltz, M.R. and Mundra, S. and Olsson, P.A. and Pent, M. and Põlme, S. and Sunagawa, S. and Ryberg, M. and Tedersoo, L. and Bork, P.
Nature 560 (7717): 233-237. 9 August 2018

Species-specific activity of antibacterial drug combinations.
Brochado, A.R. and Telzerow, A. and Bobonis, J. and Banzhaf, M. and Mateus, A. and Selkrig, J. and Huth, E. and Bassler, S. and Zamarreño Beas, J. and Zietek, M. and Ng, N. and Foerster, S. and Ezraty, B. and Py, B. and Barras, F. and Savitski, M.M. and Bork, P. and Göttig, S. and Typas, A.
Nature 559 (7713): 259-263. July 2018

Kinase-controlled phase transition of membraneless organelles in mitosis.
Rai, A.K. and Chen, J.X. and Selbach, M. and Pelkmans, L.
Nature 559 (7713): 211-216. July 2018

Extensive impact of non-antibiotic drugs on human gut bacteria.
Maier, L. and Pruteanu, M. and Kuhn, M. and Zeller, G. and Telzerow, A. and Anderson, E.E. and Brochado, A.R. and Fernandez, K.C. and Dose, H. and Mori, H. and Patil, K.R. and Bork, P. and Typas, A.
Nature 555 (7698): 623-628. 29 March 2018

Senescence-associated reprogramming promotes cancer stemness.
Milanovic, M. and Fan, D.N.Y. and Belenki, D. and Däbritz, J.H.M. and Zhao, Z. and Yu, Y. and Dörr, J.R. and Dimitrova, L. and Lenze, D. and Monteiro Barbosa, I.A. and Mendoza-Parra, M.A. and Kanashova, T. and Metzner, M. and Pardon, K. and Reimann, M. and Trumpp, A. and Dörken, B. and Zuber, J. and Gronemeyer, H. and Hummel, M. and Dittmar, G. and Lee, S. and Schmitt, C.A.
Nature 553 (7686): 96-100. 4 January 2018


IL11 is a crucial determinant of cardiovascular fibrosis.
Schafer, S. and Viswanathan, S. and Widjaja, A.A. and Lim, W.W. and Moreno-Moral, A. and DeLaughter, D.M. and Ng, B. and Patone, G. and Chow, K. and Khin, E. and Tan, J. and Chothani, S.P. and Ye, L. and Rackham, O.J. and Ko, N.S. and Sahib, N.E. and Pua, C.J. and Zhen, N.T. and Xie, C. and Wang, M. and Maatz, H. and Lim, S. and Saar, K. and Blachut, S. and Petretto, E. and Schmidt, S. and Putoczki, T. and Guimarães-Camboa, N. and Wakimoto, H. and van Heesch, S. and Sigmundsson, K. and Lim, S.L. and Soon, J.L. and Chao, V.T. and Chua, Y.L. and Tan, T.E. and Evans, S.M. and Loh, Y.J. and Jamal, M.H. and Ong, K.K. and Chua, K.C. and Ong, B.H. and Chakaramakkil, M.J. and Seidman, J.G. and Seidman, C.E. and Hubner, N. and Sin, K.Y. and Cook, S.A.
Nature 552 (7683): 110-115. 7 December 2017

Salt-responsive gut commensal modulates T(H)17 axis and disease.
Wilck, N. and Matus, M.G. and Kearney, S.M. and Olesen, S.W. and Forslund, K. and Bartolomaeus, H. and Haase, S. and Mähler, A. and Balogh, A. and Markó, L. and Vvedenskaya, O. and Kleiner, F.H. and Tsvetkov, D. and Klug, L. and Costea, P.I. and Sunagawa, S. and Maier, L. and Rakova, N. and Schatz, V. and Neubert, P. and Frätzer, C. and Krannich, A. and Gollasch, M. and Grohme, D.A. and Côrte-Real, B.F. and Gerlach, R.G. and Basic, M. and Typas, A. and Wu, C. and Titze, J.M. and Jantsch, J. and Boschmann, M. and Dechend, R. and Kleinewietfeld, M. and Kempa, S. and Bork, P. and Linker, R.A. and Alm, E.J. and Müller, D.N.
Nature 551 (7682): 585-589. 30 November 2017

Single-molecule imaging reveals receptor-G protein interactions at cell surface hot spots.
Sungkaworn, T. and Jobin, M.L. and Burnecki, K. and Weron, A. and Lohse, M.J. and Calebiro, D.
Nature 550 (7677): 543-547. 26 October 2017

A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
Elling, U. and Wimmer, R.A. and Leibbrandt, A. and Burkard, T. and Michlits, G. and Leopoldi, A. and Micheler, T. and Abdeen, D. and Zhuk, S. and Aspalter, I.M. and Handl, C. and Liebergesell, J. and Hubmann, M. and Husa, A.M. and Kinzer, M. and Schuller, N. and Wetzel, E. and van de Loo, N. and Martinez, J.A.Z. and Estoppey, D. and Riedl, R. and Yang, F. and Fu, B. and Dechat, T. and Ivics, Z. and Agu, C.A. and Bell, O. and Blaas, D. and Gerhardt, H. and Hoepfner, D. and Stark, A. and Penninger, J.M.
Nature 550 (7674): 114-118. 5 October 2017

Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.
Pieper, K. and Tan, J. and Piccoli, L. and Foglierini, M. and Barbieri, S. and Chen, Y. and Silacci-Fregni, C. and Wolf, T. and Jarrossay, D. and Anderle, M. and Abdi, A. and Ndungu, F.M. and Doumbo, O.K. and Traore, B. and Tran, T.M. and Jongo, S. and Zenklusen, I. and Crompton, P.D. and Daubenberger, C. and Bull, P.C. and Sallusto, F. and Lanzavecchia, A.
Nature 548 (7669): 597-601. 31 August 2017

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.
Pei, W. and Feyerabend, T.B. and Rössler, J. and Wang, X. and Postrach, D. and Busch, K. and Rode, I. and Klapproth, K. and Dietlein, N. and Quedenau, C. and Chen, W. and Sauer, S. and Wolf, S. and Höfer, T. and Rodewald, H.Re.
Nature 548 (7668): 456-460. 24 August 2017

Cell cycle: continuous chromatin changes.
Beagrie, R.A. and Pombo, A.
Nature 547 (7661): 34-35. 6 July 2017

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.
Varano, G. and Raffel, S. and Sormani, M. and Zanardi, F. and Lonardi, S. and Zasada, C. and Perucho, L. and Petrocelli, V. and Haake, A. and Lee, A.K. and Bugatti, M. and Paul, U. and Van Anken, E. and Pasqualucci, L. and Rabadan, R. and Siebert, R. and Kempa, S. and Ponzoni, M. and Facchetti, F. and Rajewsky, K. and Casola, S.
Nature 546 (7657): 302-306. 8 June 2017

Phylogenetic ctDNA analysis depicts early stage lung cancer evolution.
Abbosh, C. and Birkbak, N.J. and Wilson, G.A. and Jamal-Hanjani, M. and Constantin, T. and Salari, R. and Quesne, J.L. and Moore, D.A. and Veeriah, S. and Rosenthal, R. and Marafioti, T. and Kirkizlar, E. and Watkins, T.B.K. and McGranahan, N. and Ward, S. and Martinson, L. and Riley, J. and Fraioli, F. and Bakir, M.A. and Grönroos, E. and Zambrana, F. and Endozo, R. and Bi, W.L. and Fennessy, F.M. and Sponer, N. and Johnson, D. and Laycock, J. and Shafi, S. and Czyzewska-Khan, J. and Rowan, A. and Chambers, T. and Matthews, N. and Turajlic, S. and Hiley, C. and Lee, S.M. and Forster, M.D. and Ahmad, T. and Falzon, M. and Borg, E. and Lawrence, D. and Hayward, M. and Kolvekar, S. and Panagiotopoulos, N. and Janes, S.M. and Thakrar, R. and Ahmed, A. and Blackhall, F. and Summers, Y. and Hafez, D. and Naik, A. and Ganguly, A. and Kareht, S. and Shah, R. and Joseph, L. and Quinn, A.M. and Crosbie, P. and Naidu, B. and Middleton, G. and Langman, G. and Trotter, S. and Nicolson, M. and Remmen, H. and Kerr, K. and Chetty, M. and Gomersall, L. and Fennell, D.A. and Nakas, A. and Rathinam, S. and Anand, G. and Khan, S. and Russell, P. and Ezhil, V. and Ismail, B. and Irvin-Sellers, M. and Prakash, V. and Lester, J.F. and Kornaszewska, M. and Attanoos, R. and Adams, H. and Davies, H. and Oukrif, D. and Akarca, A.U. and Hartley, J.A. and Lowe, H.L. and Lock, S. and Iles, N. and Bell, H. and Ngai, Y. and Elgar, G. and Szallasi, Z. and Schwarz, R.F. and Herrero, J. and Stewart, A. and Quezada, S.A. and Van Loo, P. and Dive, C. and Lin, C.J. and Rabinowitz, M. and Aerts, H.J.W.L. and Hackshaw, A. and Shaw, J.A. and Zimmermann, B.G. and Swanton, C.
Nature 545 (7655): 446-451. 25 May 2017

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T. and Friese, C. and Arina, A. and Idel, C. and Briesemeister, D. and Rothe, M. and Ivanov, A. and Szymborska, A. and Patone, G. and Kunz, S. and Sommermeyer, D. and Engels, B. and Leisegang, M. and Textor, A. and Fehling, H.J. and Fruttiger, M. and Lohoff, M. and Herrmann, A. and Yu, H. and Weichselbaum, R. and Uckert, W. and Hübner, N. and Gerhardt, H. and Beule, D. and Schreiber, H. and Blankenstein, T.
Nature 545 (7652): 98-102. 4 May 2017

Complex multi-enhancer contacts captured by genome architecture mapping.
Beagrie, R.A. and Scialdone, A. and Schueler, M. and Kraemer, D.C.A. and Chotalia, M. and Xie, S.Q. and Barbieri, M. and de Santiago, I. and Lavitas, L.M. and Branco, M.R. and Fraser, J. and Dostie, J. and Game, L. and Dillon, N. and Edwards, P.A.W. and Nicodemi, M. and Pombo, A.
Nature 543 (7646): 519-524. 23 March 2017


Formation of new chromatin domains determines pathogenicity of genomic duplications.
Franke, M. and Ibrahim, D.M. and Andrey, G. and Schwarzer, W. and Heinrich, V. and Schoepflin, R. and Kraft, K. and Kempfer, R. and Jerkovic, I. and Chan, W.L. and Spielmann, M. and Timmermann, B. and Wittler, L. and Kurth, I. and Cambiaso, P. and Zuffardi, O. and Houge, G. and Lambie, L. and Brancati, F. and Pombo, A. and Vingron, M. and Spitz, F. and Mundlos, S.
Nature 538 (7624): 265-269. 13 October 2016

Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses.
Roux, S. and Brum, J.R. and Dutilh, B.E. and Sunagawa, S. and Duhaime, M.B. and Loy, A. and Poulos, B.T. and Solonenko, N. and Lara, E. and Poulain, J. and Pesant, S. and Kandels-Lewis, S. and Dimier, C. and Picheral, M. and Searson, S. and Cruaud, C. and Alberti, A. and Duarte, C.M. and Gasol, J.M. and Vaque, D. and Bork, P. and Acinas, S.G. and Wincker, P. and Sullivan, M.B.
Nature 537 (7622): 689-693. 29 September 2016

Human gut microbes impact host serum metabolome and insulin sensitivity.
Pedersen, H.K. and Gudmundsdottir, V. and Nielsen, H.B. and Hyotylainen, T. and Nielsen, T. and Jensen, B.A.H. and Forslund, K. and Hildebrand, F. and Prifti, E. and Falony, G. and Le Chatelier, E. and Levenez, F. and Doré, J. and Mattila, I. and Plichta, D.R. and Pöhö, P. and Hellgren, L.I. and Arumugam, M. and Sunagawa, S. and Vieira-Silva, S. and Jørgensen, T. and Holm, J.B. and Trošt, K. and Kristiansen, K. and Brix, S. and Raes, J. and Wang, J. and Hansen, T. and Bork, P. and Brunak, S. and Oresic, M. and Ehrlich, S.D. and Pedersen, O.
Nature 535 (7612): 376-381. 21 July 2016

Proteogenomics connects somatic mutations to signalling in breast cancer.
Mertins, P. and Mani, D.R. and Ruggles, K.V. and Gillette, M.A. and Clauser, K.R. and Wang, P. and Wang, X. and Qiao, J.W. and Cao, S. and Petralia, F. and Kawaler, E. and Mundt, F. and Krug, K. and Tu, Z. and Lei, J.T. and Gatza, M.L. and Wilkerson, M. and Perou, C.M. and Yellapantula, V. and Huang, K.L. and Lin, C. and McLellan, M.D. and Yan, P. and Davies, S.R. and Townsend, R.R. and Skates, S.J. and Wang, J. and Zhang, B. and Kinsinger, C.R. and Mesri, M. and Rodriguez, H. and Ding, L. and Paulovich, A.G. and Fenyoe, D. and Ellis, M.J. and Carr, S.A.
Nature 534 (7605): 55-62. 2 June 2016

Plankton networks driving carbon export in the oligotrophic ocean.
Guidi, L. and Chaffron, S. and Bittner, L. and Eveillard, D. and Larhlimi, A. and Roux, S. and Darzi, Y. and Audic, S. and Berline, L. and Brum, J. and Coelho, L.P. and Espinoza, J.C.I. and Malviya, S. and Sunagawa, S. and Dimier, C. and Kandels-Lewis, S. and Picheral, M. and Poulain, J. and Searson, S. and Stemmann, L. and Not, F. and Hingamp, P. and Speich, S. and Follows, M. and Karp-Boss, L. and Boss, E. and Ogata, H. and Pesant, S. and Weissenbach, J. and Wincker, P. and Acinas, S.G. and Bork, P. and de Vargas, C. and Iudicone, D. and Sullivan, M.B. and Raes, J. and Karsenti, E. and Bowler, C. and Gorsky, G.
Nature 532 (7600): 465-470. 28 April 2016

FOXO1 couples metabolic activity and growth state in the vascular endothelium.
Wilhelm, K. and Happel, K. and Eelen, G. and Schoors, S. and Oellerich, M.F. and Lim, R. and Zimmermann, B. and Aspalter, I.M. and Franco, C.A. and Boettger, T. and Braun, T. and Fruttiger, M. and Rajewsky, K. and Keller, C. and Brüning, J.C. and Gerhardt, H. and Carmeliet, P. and Potente, M.
Nature 529 (7585): 216-220. 14 January 2016

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.
Tan, J. and Pieper, K. and Piccoli, L. and Abdi, A. and Foglierini, M. and Geiger, R. and Tully, C.M. and Jarrossay, D. and Ndungu, F.M. and Wambua, J. and Bejon, P. and Silacci Fregni, C. and Fernandez-Rodriguez, B. and Barbieri, S. and Bianchi, S. and Marsh, K. and Thathy, V. and Corti, D. and Sallusto, F. and Bull, P. and Lanzavecchia, A.
Nature 529 (7584): 105-109. 7 January 2016


Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.
Forslund, K. and Hildebrandt, F. and Nielsen, T. and Falony, G. and Le Chatelier, E. and Sunagawa, S. and Prifti, E. and Vieira-Silva, S. and Gudmundsdottir, V. and Pedersen, H.K. and Arumugam, M. and Kristiansen, K. and Voigt, A.Y. and Vestergaard, H. and Hercog, R. and Costea, P.I. and Kultima, J.R. and Li, J. and Jørgensen, T. and Levenez, F. and Dore, J. and Nielsen, H.B. and Brunak, S. and Raes, J. and Hansen, T. and Wang, J. and Ehrlich, S.D. and Bork, P. and Pedersen, O.
Nature 528 (7581): 262-266. 10 December 2015

Crystal structure of the dynamin tetramer.
Reubold, T.F. and Faelber, K. and Plattner, N. and Posor, Y. and Ketel, K. and Curth, U. and Schlegel, J. and Anand, R. and Manstein, D.J. and Noé, F. and Haucke, V. and Daumke, O. and Eschenburg, S.
Nature 525 (7569): 404-408. 17 September 2015

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation.
Baubec, T. and Colombo, D.F. and Wirbelauer, C. and Schmidt, J. and Burger, L. and Krebs, A.R. and Akalin, A. and Schübeler, D.
Nature 520 (7546): 243-247. 9 April 2015

Fatty acid carbon is essential for dNTP synthesis in endothelial cells.
Schoors, S. and Bruning, U. and Missiaen, R. and Queiroz, K.C.S. and Borgers, G. and Elia, I. and Zecchin, A. and Cantelmo, A.R. and Christen, S. and Goveia, J. and Heggermont, W. and Goddé, L. and Vinckier, S. and Van Veldhoven, P.P. and Eelen, G. and Schoonjans, L. and Gerhardt, H. and Dewerchin, M. and Baes, M. and De Bock, K. and Ghesquière, B. and Lunt, S.Y. and Fendt, S.M. and Carmeliet, P.
Nature 520 (7546): 192-197. 9 April 2015

PLD3 in non-familial Alzheimer's disease.
Heilmann, S. and Drichel, D. and Clarimon, J. and Fernández, V. and Lacour, A. and Wagner, H. and Thelen, M. and Hernández, I. and Fortea, J. and Alegret, M. and Blesa, R. and Mauleón, A. and Roca, M.R. and Kornhuber, J. and Peters, O. and Heun, R. and Frölich, L. and Hüll, M. and Heneka, M.T. and Rüther, E. and Riedel-Heller, S. and Scherer, M. and Wiltfang, J. and Jessen, F. and Becker, T. and Tárraga, L. and Boada, M. and Maier, W. and Lleó, A. and Ruiz, A. and Nöthen, M.M. and Ramirez, A.
Nature 520 (7545): E3-E5. 2 April 2015


Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J. and Xie, G. and Singh, M. and Ghanbarian, A.T. and Raskó, T. and Szvetnik, A. and Cai, H. and Besser, D. and Prigione, A. and Fuchs, N.V. and Schumann, G.G. and Chen, W. and Lorincz, M.C. and Ivics, Z. and Hurst, L.D. and Izsvák, Z.
Nature 516 (7531): 405-409. 18 December 2014

Piezo2 is the major transducer of mechanical forces for touch sensation in mice.
Ranade, S.S. and Woo, S.H. and Dubin, A.E. and Moshourab, R.A. and Wetzel, C. and Petrus, M. and Mathur, J. and Bégay, V. and Coste, B. and Mainquist, J. and Wilson, A.J. and Francisco, A.G. and Reddy, K. and Qiu, Z. and Wood, J.N. and Lewin, G.R. and Patapoutian, A.
Nature 516 (7529): 121-125. 4 December 2014

Gibbon genome and the fast karyotype evolution of small apes.
Carbone, L. and Harris, R.A. and Gnerre, S. and Veeramah, K.R. and Lorente-Galdos, B. and Huddleston, J. and Meyer, T.J. and Herrero, J. and Roos, C. and Aken, B. and Anaclerio, F. and Archidiacono, N. and Baker, C. and Barrell, D. and Batzer, M.A. and Beal, K. and Blancher, A. and Bohrson, C.L. and Brameier, M. and Campbell, M.S. and Capozzi, O. and Casola, C. and Chiatante, G. and Cree, A. and Damert, A. and de Jong, P.J. and Dumas, L. and Fernandez-Callejo, M. and Flicek, P. and Fuchs, N.V. and Gut, I. and Gut, M. and Hahn, M.W. and Hernandez-Rodriguez, J. and Hillier, L.W. and Hubley, R. and Ianc, B. and Izsvák, Z. and Jablonski, N.G. and Johnstone, L.M. and Karimpour-Fard, A. and Konkel, M.K. and Kostka, D. and Lazar, N.H. and Lee, S.L. and Lewis, L.R. and Liu, Y. and Locke, D.P. and Mallick, S. and Mendez, F.L. and Muffato, M. and Nazareth, L.V. and Nevonen, K.A. and O'Bleness, M. and Ochis, C. and Odom, D.T. and Pollard, K.S. and Quilez, J. and Reich, D. and Rocchi, M. and Schumann, G.G. and Searle, S. and Sikela, J.M. and Skollar, G. and Smit, A. and Sonmez, K. and ten Hallers, B. and Terhune, E. and Thomas, G.W.C. and Ullmer, B. and Ventura, M. and Walker, J.A. and Wall, J.D. and Walter, L. and Ward, M.C. and Wheelan, S.J. and Whelan, C.W. and White, S. and Wilhelm, L.J. and Woerner, A.E. and Yandell, M. and Zhu, B. and Hammer, M.F. and Marques-Bonet, T. and Eichler, E.E. and Fulton, L. and Fronick, C. and Muzny, D.M. and Warren, W.C. and Worley, K.C. and Rogers, J. and Wilson, R.K. and Gibbs, R.A.
Nature 513 (7517): 195-201. 11 September 2014

Developmental biology: it takes muscle to make blood cells.
Sawamiphak, S. and Stainier, D.Y.R.
Nature 512 (7514): 257-258. 21 August 2014

Two independent transcription initiation codes overlap on vertebrate core promoters.
Haberle, V. and Li, N. and Hadzhiev, Y. and Plessy, C. and Previti, C. and Nepal, C. and Gehrig, J. and Dong, X. and Akalin, A. and Suzuki, A.M. and van IJcken, W.F.J. and Armant, O. and Ferg, M. and Strähle, U. and Carninci, P. and Müller, F. and Lenhard, B.
Nature 507 (7492): 381-385. 20 March 2014

Bone biology: vessels of rejuvenation.
Le Noble, F. and Le Noble, J.
Nature 507 (7492): 313-314. 20 March 2014


Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
Dörr, J.R. and Yu, Y. and Milanovic, M. and Beuster, G. and Zasada, C. and Däbritz, J.H.M. and Lisec, J. and Lenze, D. and Gerhardt, A. and Schleicher, K. and Kratzat, S. and Purfürst, B. and Walenta, S. and Mueller-Klieser, W. and Gräler, M. and Hummel, M. and Keller, U. and Buck, A.K. and Dörken, B. and Willmitzer, L. and Reimann, M. and Kempa, S. and Lee, S. and Schmitt, C.A.
Nature 501 (7467): 421-425. 19 September 2013

M-CSF instructs myeloid lineage fate in single haematopoietic stem cells.
Mossadegh-Keller, N. and Sarrazin, S. and Kandalla, P.K. and Espinosa, L. and Stanley, E.R. and Nutt, S.L. and Moore, J. and Sieweke, M.H.
Nature 497 (7448): 239-243. 9 May 2013

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.
Kleinewietfeld, M. and Manzel, A. and Titze, J. and Kvakan, H. and Yosef, N. and Linker, R.A. and Muller, D.N. and Hafler, D.A.
Nature 496 (7446): 518-522. 25 April 2013

Circular RNAs are a large class of animal RNAs with regulatory potency.
Memczak, S. and Jens, M. and Elefsinioti, A. and Torti, F. and Krueger, J. and Rybak, A. and Maier, L. and Mackowiak, S.D. and Gregersen, L.H. and Munschauer, M. and Loewer, A. and Ziebold, U. and Landthaler, M. and Kocks, C. and le Noble, F. and Rajewsky, N.
Nature 495 (7441): 333-338. 21 March 2013

Genomic variation landscape of the human gut microbiome.
Schloissnig, S. and Arumugam, M. and Sunagawa, S. and Mitreva, M. and Tap, J. and Zhu, A. and Waller, A. and Mende, D.R. and Kultima, J.R. and Martin, J. and Kota, K. and Sunyaev, S.R. and Weinstock, G.M. and Bork, P.
Nature 493 (7430): 45-50. 3 January 2013


FMRP targets distinct mRNA sequence elements to regulate protein expression.
Ascano, M. and Mukherjee, N. and Bandaru, P. and Miller, J.B. and Nusbaum, J.D. and Corcoran, D.L. and Langlois, C. and Munschauer, M. and Dewell, S. and Hafner, M. and Williams, Z. and Ohler, U. and Tuschl, T.
Nature 492 (7429): 382-386. 20 December 2012

Tissue engineering: Blood vessels on a chip.
Franco, C. and Gerhardt, H.
Nature 488 (7412): 465-466. 23 August 2012

The clonal and mutational evolution spectrum of primary triple-negative breast cancers.
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Nature 486 (7403): 395-399. 21 June 2012

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Nature 486 (7402): 256-260. 29 April 2012

Deregulated MYC expression induces dependence upon AMPK-related kinase 5.
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Nature 483 (7391): 608-612. 29 March 2012


Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.
McDermott-Roe, C. and Ye, J. and Ahmed, R. and Sun, X.M. and Serafin, A. and Ware, J. and Bottolo, L. and Muckett, P. and Canas, X. and Zhang, J. and Rowe, G.C. and Buchan, R. and Lu, H. and Braithwaite, A. and Mancini, M. and Hauton, D. and Marti, R. and Garcia-Arumi, E. and Hubner, N. and Jacob, H. and Serikawa, T. and Zidek, V. and Papousek, F. and Kolar, F. and Cardona, M. and Ruiz-Meana, M. and Garcia-Dorado, D. and Comella, J.X. and Felkin, L.E. and Barton, P.J. and Arany, Z. and Pravenec, M. and Petretto, E. and Sanchis, D. and Cook, S.A.
Nature 478 (7367): 114-118. 6 October 2011

Deep sequencing reveals 50 novel genes for recessive cognitive disorders.
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Nature 478 (7367): 57-63. 6 October 2011

Crystal structure of nucleotide-free dynamin.
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Nature 477 (7366): 556-560. 29 September 2011

Stem cells: Orphan receptors find a home.
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Nature 476 (7360): 287-288. 18 August 2011

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.
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Nature 476 (7360): 298-303. 18 August 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
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Nature 476 (7359): 214-219. 10 August 2011

Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.
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Nature 474 (7352): 511-515. 23 June 2011

Global quantification of mammalian gene expression control.
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Nature 473 (7347): 337-342. 19 May 2011

Enterotypes of the human gut microbiome.
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Nature 473 (7346): 174-180. 12 May 2011

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase.
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Nature 473 (7346): 234-238. 12 May 2011


Gene expression divergence recapitulates the developmental hourglass model.
Kalinka, A.T. and Varga, K.M. and Gerrard, D.T. and Preibisch, S. and Corcoran, D.L. and Jarrells, J. and Ohler, U. and Bergman, C.M. and Tomancak, P.
Nature 468 (7325): 811-814. 9 December 2010

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.
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Nature 467 (7314): 460-464. 23 September 2010

Wnt11 patterns a myocardial electrical gradient through regulation of the L-type Ca(2+) channel.
Panakova, D. and Werdich, A.A. and Macrae, C.A.
Nature 466 (7308): 874-878. 12 August 2010

Loss of fish actinotrichia proteins and the fin-to-limb transition.
Zhang, J. and Wagh, P. and Guay, D. and Sanchez-Pulido, L. and Padhi, B.K. and Korzh, V. and Andrade-Navarro, M.A. and Akimenko, M.A.
Nature 466 (7303): 234-237. 8 July 2010

Developmental sensory experience balances cortical excitation and inhibition.
Dorrn, A.L. and Yuan, K. and Barker, A.J. and Schreiner, C.E. and Froemke, R.C.
Nature 465 (7300): 932-936. 17 June 2010

Structural basis of oligomerization in the stalk region of dynamin-like MxA.
Gao, S. and von der Malsburg, A. and Paeschke, S. and Behlke, J. and Haller, O. and Kochs, G. and Daumke, O.
Nature 465 (7297): 502-506. 27 May 2010

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis.
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Nature 465 (7297): 487-491. 27 May 2010

The genome of a songbird.
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Nature 464 (7289): 757-762. 1 April 2010

Ancient animal microRNAs and the evolution of tissue identity.
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Nature 463 (7284): 1084-1088. 25 February 2010


Central control of fever and female body temperature by RANKL/RANK.
Hanada, R. and Leibbrandt, A. and Hanada, T. and Kitaoka, S. and Furuyashiki, T. and Fujihara, H. and Trichereau, J. and Paolino, M. and Qadri, F. and Plehm, R. and Klaere, S. and Komnenovic, V. and Mimata, H. and Yoshimatsu, H. and Takahashi, N. and von Haeseler, A. and Bader, M. and Kilic, S.S. and Ueta, Y. and Pifl, C. and Narumiya, S. and Penninger, J.M.
Nature 462 (7272): 505-509. 26 November 2009

Combinatorial binding predicts spatio-temporal cis-regulatory activity.
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Nature 462 (7269): 65-70. 5 November 2009

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
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Nature 459 (7249): 1000-1004. 18 June 2009

Clustering of InsP3 receptors by InsP3 retunes their regulation by InsP3 and Ca2+.
Taufiq-Ur-Rahman, and Skupin, A. and Falcke, M. and Taylor, C.W.
Nature 458 (7238): 655-659. 2 April 2009

The ubiquitylation machinery of the endoplasmic reticulum.
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Nature 458 (7237): 453-460. 26 March 2009


The genome of the simian and human malaria parasite Plasmodium knowlesi.
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Nature 455 (7214): 799-803. 9 October 2008

Widespread changes in protein synthesis induced by microRNAs.
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Nature 455 (7209): 58-63. 4 September 2008

Internal brain state regulates membrane potential synchrony in barrel cortex of behaving mice.
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Nature 454 (7206): 881-885. 14 August 2008

Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration.
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Nature 453 (7195): 662-666. 29 May 2008

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population.
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Nature 453 (7194): 524-528. 22 May 2008

The genome of the model beetle and pest tribolium castaneum.

Nature 452 (7190): 949-955. 24 April 2008

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.
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Nature 452 (7187): 650-653. 3 April 2008

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans.
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Nature 451 (7180): 783-788. 14 February 2008


A viral microRNA functions as an orthologue of cellular miR-155.
Gottwein, E. and Mukherjee, N. and Sachse, C. and Frenzel, C. and Majoros, W.H. and Chi, J.T.A. and Braich, R. and Manoharan, M. and Soutschek, J. and Ohler, U. and Cullen, B.R.
Nature 450 (7172): 1096-1099. 13 December 2007

Helicobacter exploits integrin for type IV secretion and kinase activation.
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Nature 449 (7164): 862-866. 18 October 2007

Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling.
Daumke, O. and Lundmark, R. and Vallis, Y. and Martens, S. and Butler, P.J.G. and McMahon, H.T.
Nature 449 (7164): 923-927. 3 October 2007

The menthol receptor TRPM8 is the principal detector of environmental cold.
Bautista, D.M. and Siemens, J. and Glazer, J.M. and Tsuruda, P.R. and Basbaum, A.I. and Stucky, C.L. and Jordt, S.E. and Julius, D.
Nature 448 (7150): 204-208. 12 July 2007

Neuroscience: The brain's garbage men.
Kettenmann, H.
Nature 446 (7139): 987-989. 26 April 2007

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
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Nature 445 (7129): 776-780. 15 February 2007

A stomatin-domain protein essential for touch sensation in the mouse.
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Nature 445 (7124): 206-209. 11 January 2007


Spider toxins activate the capsaicin receptor to produce inflammatory pain.
Siemens, J.E. and Zhou, S. and Piskorowski, R. and Nikai, T. and Lumpkin, E.A. and Basbaum, A.I. and King, D. and Julius, D.
Nature 444 (7116): 208-212. 9 November 2006

Insights into social insects from the genome of the honeybee Apis mellifera.

Nature 443 (7114): 931-949. 26 October 2006

Co-evolution of transcriptional and post-translational cell-cycle regulation.
Jensen, L.J. and Jensen, T.S. and de Lichtenberg, U. and Brunak, S. and Bork, P.
Nature 443 (7111): 594-597. 4 October 2006

Hungary's 'reforms' are threatening basic science.
Izsvak, Z. and Ivics, Z. and Mates, L.
Nature 443 (7110): 394. 28 September 2006

Proteome survey reveals modularity of the yeast cell machinery.
Gavin, A.C. and Aloy, P. and Grandi, P. and Krause, R. and Boesche, M. and Marzioch, M. and Rau, C. and Jensen, L.J. and Bastuck, S. and Duempelfeld, B. and Edelmann, A. and Heurtier, M.A. and Hoffman, V. and Hoefert, C. and Klein, K. and Hudak, M. and Michon, A.M. and Schelder, M. and Schirle, M. and Remor, M. and Rudi, T. and Hooper, S. and Bauer, A. and Bouwmeester, T. and Casari, G. and Drewes, G. and Neubauer, G. and Rick, J.M. and Kuster, B. and Bork, P. and Russell, R.B. and Superti-Furga, G.
Nature 440 (7084): 631-636. 30 March 2006

Robust Salmonella metabolism limits possibilities for new antimicrobials.
Becker, D. and Selbach, M. and Rollenhagen, C. and Ballmaier, M. and Meyer, T.F. and Mann, M. and Bumann, D.
Nature 440 (7082): 303-307. 16 March 2006

ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function.
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Nature 440 (7081): 220-223. 9 March 2006


Silencing of microRNAs in vivo with 'antagomirs'.
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Nature 438 (7068): 685-689. 1 December 2005

Initial sequence of the chimpanzee genome and comparison with the human genome.
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Nature 437 (7055): 69-87. 1 September 2005

Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance.
Willimsky, G. and Blankenstein, T.
Nature 437 (7055): 141-146. 1 September 2005

Oncogene-induced senescence as an initial barrier in lymphoma development.
Braig, M. and Lee, S. and Loddenkemper, C. and Rudolph, C. and Peters, A.H. and Schlegelberger, B. and Stein, H. and Doerken, B. and Jenuwein, T. and Schmitt, C.A.
Nature 436 (7051): 660-665. 4 August 2005

Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins.
Scheel, O. and Zdebik, A.A. and Lourdel, S. and Jentsch, T.J.
Nature 436 (7049): 424-427. 21 July 2005

Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
Hillier, L.W. and Graves, T.A. and Fulton, R.S. and Fulton, L.A. and Pepin, K.H. and Minx, P. and Wagner-McPherson, C. and Layman, D. and Wylie, K. and Sekhon, M. and Becker, M.C. and Fewell, G.A. and Delehaunty, K.D. and Miner, T.L. and Nash, W.E. and Kremitzki, C. and Oddy, L. and Du, H. and Sun, H. and Bradshaw-Cordum, H. and Ali, J. and Carter, J. and Cordes, M. and Harris, A. and Isak, A. and van Brunt, A. and Nguyen, C. and Du, F. and Courtney, L. and Kalicki, J. and Ozersky, P. and Abbott, S. and Armstrong, J. and Belter, E.A. and Caruso, L. and Cedroni, M. and Cotton, M. and Davidson, T. and Desai, A. and Elliott, G. and Erb, T. and Fronick, C. and Gaige, T. and Haakenson, W. and Haglund, K. and Holmes, A. and Harkins, R. and Kim, K. and Kruchowski, S.S. and Strong, C.M. and Grewal, N. and Goyea, E. and Hou, S. and Levy, A. and Martinka, S. and Mead, K. and McLellan, M.D. and Meyer, R. and Randall-Maher, J. and Tomlinson, C. and uphin-Kohlberg, S. and Kozlowicz-Reilly, A. and Shah, N. and Swearengen-Shahid, S. and Snider, J. and Strong, J.T. and Thompson, J. and Yoakum, M. and Leonard, S. and Pearman, C. and Trani, L. and Radionenko, M. and Waligorski, J.E. and Wang, C. and Rock, S.M. and Tin-Wollam, A.M. and Maupin, R. and Latreille, P. and Wendl, M.C. and Yang, S.P. and Pohl, C. and Wallis, J.W. and Spieth, J. and Bieri, T.A. and Berkowicz, N. and Nelson, J.O. and Osborne, J. and Ding, L. and Meyer, R. and Sabo, A. and Shotland, Y. and Sinha, P. and Wohldmann, P.E. and Cook, L.L. and Hickenbotham, M.T. and Eldred, J. and Williams, D. and Jones, T.A. and She, X. and Ciccarelli, F.D. and Izaurralde, E. and Taylor, J. and Schmutz, J. and Myers, R.M. and Cox, D.R. and Huang, X. and McPherson, J.D. and Mardis, E.R. and Clifton, S.W. and Warren, W.C. and Chinwalla, A.T. and Eddy, S.R. and Marra, M.A. and Ovcharenko, I. and Furey, T.S. and Miller, W. and Eichler, E.E. and Bork, P. and Suyama, M. and Torrents, D. and Waterston, R.H. and Wilson, R.K.
Nature 434 : 724-731. 1 January 2005


Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.
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Nature 432 (7018): 695-716. 9 December 2004

The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system.
Lu, X. and Le Noble, F. and Yuan, L. and Jiang, Q. and De Lafarge, B. and Sugiyama, D. and Breant, C. and Claes, F. and De Smet, F. and Thomas, J.L. and Autiero, M. and Carmeliet, P. and Tessier-Lavigne, M. and Eichmann, A.
Nature 432 (7014): 179-186. 11 November 2004

A pancreatic islet-specific microRNA regulates insulin secretion.
Poy, M.N. and Eliasson, L. and Krutzfeldt, J. and Kuwajima, S. and Ma, X. and Macdonald, P.E. and Pfeffer, S. and Tuschl, T. and Rajewsky, N. and Rorsman, P. and Stoffel, M.
Nature 432 (7014): 226-230. 11 November 2004

Complex auditory behaviour emerges from simple reactive steering.
Hedwig, B. and Poulet, J.F.A.
Nature 430 (7001): 781-785. 12 August 2004

Cadherin 23 is a component of the tip link in hair-cell stereocilia.
Siemens, J. and Lillo, C. and Dumont, R.A. and Reynolds, A. and Williams, D.S. and Gillespie, P.G. and Mueller, U.
Nature 428 (6986): 950-955. 29 April 2004

Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells.
Soellner, C. and Rauch, G.J. and Siemens, J. and Geisler, R. and Schuster, S.C. and Mueller, U. and Nicolson, T.
Nature 428 (6986): 955-959. 29 April 2004

Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs, R.A. and Weinstock, G.M. and Metzker, M.L. and Muzny, D.M. and Sodergren, E.J. and Scherer, S. and Scott, G. and Steffen, D. and Worley, K.C. and Burch, P.E. and Okwuonu, G. and Hines, S. and Lewis, L. and DeRamo, C. and Delgado, O. and Dugan-Rocha, S. and Miner, G. and Morgan, M. and Hawes, A. and Gill, R. and Holt, R.A. and Adams, M.D. and Amanatides, P.G. and Baden-Tillson, H. and Barnstead, M. and Chin, S. and Evans, C.A. and Ferriera, S. and Fosler, C. and Glodek, A. and Gu, Z. and Jennings, D. and Kraft, C.L. and Nguyen, T. and Pfannkoch, C.M. and Sitter, C. and Sutton, G.G. and Venter, J.C. and Woodage, T. and Smith, D. and Lee, H.M. and Gustafson, E. and Cahill, P. and Kana, A. and Doucette-Stamm, L. and Weinstock, K. and Fechtel, K. and Weiss, R.B. and Dunn, D.M. and Green, E.D. and Blakesley, R.W. and Bouffard, G.G. and de Jong, P.J. and Osoegawa, K. and Zhu, B. and Marra, M. and Schein, J. and Bosdet, I. and Fjell, C. and Jones, S. and Krzywinski, M. and Mathewson, C. and Siddiqui, A. and Wye, N. and McPherson, J. and Zhao, S. and Fraser, C.M. and Shetty, J. and Shatsman, S. and Geer, K. and Chen, Y. and Abramzon, S. and Nierman, W.C. and Havlak, P.H. and Chen, R. and Durbin, K.J. and Egan, A. and Ren, Y. and Song, X.Z. and Li, B. and Liu, Y. and Qin, X. and Cawley, S. and Worley, K.C. and Cooney, A.J. and D'Souza, L.M. and Martin, K. and Wu, J.Q. and Gonzalez-Garay, M.L. and Jackson, A.R. and Kalafus, K.J. and McLeod, M.P. and Milosavljevic, A. and Virk, D. and Volkov, A. and Wheeler, D.A. and Zhang, Z. and Bailey, J.A. and Eichler, E.E. and Tuzun, E. and Birney, E. and Mongin, E. and Ureta-Vidal, A. and Woodwark, C. and Zdobnov, E. and Bork, P. and Suyama, M. and Torrents, D. and Alexandersson, M. and Trask, B.J. and Young, J.M. and Huang, H. and Wang, H. and Xing, H. and Daniels, S. and Gietzen, D. and Schmidt, J. and Stevens, K. and Vitt, U. and Wingrove, J. and Camara, F. and Alba, M.M. and Abril, J.F. and Guigo, R. and Smit, A. and Dubchak, I. and Rubin, E.M. and Couronne, O. and Poliakov, A. and Huebner, N. and Ganten, D. and Goesele, C. and Hummel, O. and Kreitler, T. and Lee, Y.A. and Monti, J. and Schulz, H. and Zimdahl, H. and Himmelbauer, H. and Lehrach, H. and Jacob, H.J. and Bromberg, S. and Gullings-Handley, J. and Jensen-Seaman, M.I. and Kwitek, A.E. and Lazar, J. and Pasko, D. and Tonellato, P.J. and Twigger, S. and Ponting, C.P. and Duarte, J.M. and Rice, S. and Goodstadt, L. and Beatson, S.A. and Emes, R.D. and Winter, E.E. and Webber, C. and Brandt, P. and Nyakatura, G. and Adetobi, M. and Chiaromonte, F. and Elnitski, L. and Eswara, P. and Hardison, R.C. and Hou, M. and Kolbe, D. and Makova, K. and Miller, W. and Nekrutenko, A. and Riemer, C. and Schwartz, S. and Taylor, J. and Yang, S. and Zhang, Y. and Lindpaintner, K. and Andrews, T.D. and Caccamo, M. and Clamp, M. and Clarke, L. and Curwen, V. and Durbin, R. and Eyras, E. and Searle, S.M. and Cooper, G.M. and Batzoglou, S. and Brudno, M. and Sidow, A. and Stone, E.A. and Venter, J.C. and Payseur, B.A. and Bourque, G. and Lopez-Otin, C. and Puente, X.S. and Chakrabarti, K. and Chatterji, S. and Dewey, C. and Pachter, L. and Bray, N. and Yap, V.B. and Caspi, A. and Tesler, G. and Pevzner, P.A. and Haussler, D. and Roskin, K.M. and Baertsch, R. and Clawson, H. and Furey, T.S. and Hinrichs, A.S. and Karolchik, D. and Kent, W.J. and Rosenbloom, K.R. and Trumbower, H. and Weirauch, M. and Cooper, D.N. and Stenson, P.D. and Ma, B. and Brent, M. and Arumugam, M. and Shteynberg, D. and Copley, R.R. and Taylor, M.S. and Riethman, H. and Mudunuri, U. and Peterson, J. and Guyer, M. and Felsenfeld, A. and Old, S. and Mockrin, S. and Collins, F.
Nature 428 (6982): 493-521. 1 April 2004

Sortilin is essential for proNGF-induced neuronal cell death.
Nykjaer, A. and Lee, R. and Teng, K.K. and Jansen, P. and Madsen, P. and Nielsen, M.S. and Jacobsen, C. and Kliemannel, M. and Schwarz, E. and Willnow, T.E. and Hempstead, B.L. and Petersen, C.M.
Nature 427 (6977): 843-848. 26 February 2004


Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion.
Prinz, M. and Heikenwalder, M. and Junt, T. and Schwarz, P. and Glatzel, M. and Heppner, F.L. and Fu, Y.X. and Lipp, M. and Aguzzi, A.
Nature 425 (6961): 957-962. 30 October 2003

The DNA sequence of human chromosome 7.
Hillier, L.W. and Fulton, R.S. and Fulton, L.A. and Graves, T.A. and Pepin, K.H. and Wagner-McPherson, C. and Layman, D. and Maas, J. and Jaeger, S. and Walker, R. and Wylie, K. and Sekhon, M. and Becker, M.C. and O'Laughlin, M.D. and Schaller, M.E. and Fewell, G.A. and Delehaunty, K.D. and Miner, T.L. and Nash, W.E. and Cordes, M. and Du, H. and Sun, H. and Edwards, J. and Bradshaw-Cordum, H. and Ali, J. and Andrews, S. and Isak, A. and VanBrunt, A. and Nguyen, C. and Du, F.Y. and Lamar, B. and Courtney, L. and Kalicki, J. and Ozersky, P. and Bielicki, L. and Scott, K. and Holmes, A. and Harkins, R. and Harris, A. and Strong, C.M. and Hou, S.F. and Tomlinson, C. and Dauphin-Kohlberg, S. and Kozlowicz-Reilly, A. and Leonard, S. and Rohlfing, T. and Rock, S.M. and Tin-Wollam, A.M. and Abbott, A. and Minx, P. and Maupin, R. and Strowmatt, C. and Latreille, P. and Miller, N. and Johnson, D. and Murray, J. and Woessner, J.P. and Wendl, M.C. and Yang, S.P. and Schultz, B.R. and Wallis, J.W. and Spieth, J. and Bieri, T.A. and Nelson, J.O. and Berkowicz, N. and Wohldmann, P.E. and Cook, L.L. and Hickenbotham, M.T. and Eldred, J. and Williams, D. and Bedell, J.A. and Mardis, E.R. and Clifton, S.W. and Chissoe, S.L. and Marra, M.A. and Raymond, C. and Haugen, E. and Gillett, W. and Zhou, Y. and James, R. and Phelps, K. and Iadanoto, S. and Bubb, K. and Simms, E. and Levy, R. and Clendenning, J. and Kaul, R. and Kent, W.J. and Furey, T.S. and Baertsch, R.A. and Brent, M.R. and Keibler, E. and Flicek, P. and Bork, P. and Suyama, M. and Bailey, J.A. and Portnoy, M.E. and Torrents, D. and Chinwalla, A.T. and Gish, W.R. and Eddy, S.R. and McPherson, J.D. and Olson, M.V. and Eichler, E.E. and Green, E.D. and Waterston, R.H. and Wilson, R.K.
Nature 424 : 157-164. 1 January 2003


Initial sequencing and comparative analysis of the mouse genome.
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Nature 420 (6915): 520-562. 5 December 2002

Metabolic network structure determines key aspects of functionality and regulation.
Stelling, J. and Klamt, S. and Bettenbrock, K. and Schuster, S. and Gilles, E.D.
Nature 420 (6912): 190-193. 14 November 2002

A corollary discharge maintains auditory sensitivity during sound production.
Poulet, J.F.A. and Hedwig, B.
Nature 418 (6900): 872-876. 22 August 2002

Genome organization: Teamed up for transcription.
von Mering, C. and Bork, P.
Nature 417 (6891): 797-798. 20 June 2002

Comparative assessment of large-scale data sets of protein-protein interactions.
von Mering, C. and Krause, R. and Snel, B. and Cornell, M. and Oliver, S.G. and Fields, S. and Bork, P.
Nature 417 (6887): 399-403. 23 May 2002

Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter Kcc4.
Boettger, T. and Huebner, C.A. and Maier, H. and Rust, M.B. and Beck, F.X. and Jentsch, T.J.
Nature 416 (6883): 874-878. 25 April 2002

Chloride channels are different.
Jentsch, T.J.
Nature 415 (6869): 276-277. 17 January 2002

Functional organization of the yeast proteome by systematic analysis of protein complexes.
Gavin, A.C. and Boesche, M. and Krause, R. and Grandi, P. and Marzioch, M. and Bauer, A. and Schultz, J. and Rick, J.M. and Michon, A.M. and Cruciat, C.M. and Remor, M. and Hoefert, C. and Schelder, M. and Brajenovic, M. and Ruffner, H. and Merino, A. and Klein, K. and Hudak, M. and Dickson, D. and Rudi, T. and Gnau, V. and Bauch, A. and Bastuck, S. and Huhse, B. and Leutwein, C. and Heurtier, M.A. and Copley, R.R. and Edelmann, A. and Querfurth, E. and Rybin, V. and Drewes, G. and Raida, M. and Bouwmeester, T. and Bork, P. and Seraphin, B. and Kuester, B. and Neubauer, G. and Superti-Furga, G.
Nature 415 (6868): 141-147. 10 January 2002

Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position.
Reif, K. and Ekland, E.H. and Ohl, L. and Nakano, H. and Lipp, M. and Foerster, R. and Cyster, J.G.
Nature 416 : 94-99. 1 January 2002


Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.
Estevez, R. and Boettger, T. and Stein, V. and Birkenhaeger, R. and Otto, E. and Hildebrandt, F. and Jentsch, T.J.
Nature 414 (6863): 558-561. 29 November 2001

Planned law could put German research at risk.
Jentsch, T.
Nature 413 (6858): 772. 25 October 2001

Hero or villain? Stasi archives shed light on russian scientist.
Hossfeld, U. and Walker, M.
Nature 411 (6835): 237. 17 May 2001

Skewed maturation of memory HIV-specific CD8 T lymphocytes.
Champagne, P. and Ogg, G.S. and King, A.S. and Knabenhans, C. and Ellefsen, K. and Nobile, M. and Appay, V. and Rizzardi, G.P. and Fleury, S. and Lipp, M. and Foerster, R. and Rowland-Jones, S. and Sekaly, R.P. and McMichael, A.J. and Pantaleo, G.
Nature 410 (6824): 106-111. 1 March 2001

The draft sequences. Filling in the gaps.
Bork, P. and Copley, R.
Nature 409 (6822): 818-820. 15 February 2001

Initial sequencing and analysis of the human genome.
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Nature 409 (6822): 860-921. 15 February 2001

Genome speak.
Bork, P. and Copley, R.
Nature 409 : 815. 1 January 2001


Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III.
Gonczy, P. and Echeverri, G. and Oegema, K. and Coulson, A. and Jones, S.J. and Copley, R.R. and Duperon, J. and Oegema, J. and Brehm, M. and Cassin, E. and Hannak, E. and Kirkham, M. and Pichler, S. and Flohrs, K. and Goessen, A. and Leidel, S. and Alleaume, A.M. and Martin, C. and Ozlu, N. and Bork, P. and Hyman, A.A.
Nature 408 (6810): 331-336. 16 November 2000

ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease.
Piwon, N. and Guenther, W. and Schwake, M. and Boesl, M.R. and Jentsch, T.J.
Nature 408 (6810): 369-373. 16 November 2000

The mammalian sodium channel BNC1 is required for normal touch sensation.
Price, M.P. and Lewin, G.R. and McIlwrath, S.L. and Cheng, C. and Xie, J.H. and Heppenstall, P.A. and Stucky, C.L. and Mannsfeldt, A.G. and Brennan, T.J. and Drummond, H.A. and Qiao, J. and Benson, C.J. and Tarr, D.E. and Hrstka, R.F. and Yang, B.L. and Williamson, R.A. and Welsh, M.J.
Nature 407 (6807): 1007-1011. 26 October 2000

Kainate receptors and synaptic plasticity.
Nicoll, R.A. and Mellor, J. and Frerking, M. and Schmitz, D.
Nature 406 (6799): 957. 31 August 2000

A chemokine-driven positive feedback loop organizes lymphoid follicles.
Ansel, K.M. and Ngo, V.N. and Hyman, P.L. and Luther, S.A. and Foerster, R. and Sedgwick, J.D. and Browning, J.L. and Lipp, M. and Cyster, J.G.
Nature 406 (6793): 309-314. 20 July 2000

A function for dysfunction - Ion channels and disease.
Jentsch, T.J.
Nature 406 (6793): 236-237. 20 July 2000

Distinguished scientists back Germany's DFG . .
Jahn, R. and Boeck, A. and Breiner, K.M. and Breunig, K.D. and Bujard, H. and Campos-Ortega, J. and Ganten, D. and Grummt, I. and Gruss, P. and Goridis, C. and Huber, R. and Hoch, M. and Jaeckle, H. and Kahmann, R. and Koch-Brandt, C. and Leptin, M. and Michel, H. and Noegel, A. and Neher, E. and Nuesslein-Volhard, C. and Pfanner, N. and Sandhoff, K. and Schoen, A. and Schwille, P. and Simons, K. and Zrenner, E.
Nature 404 : 922-922. 27 April 2000

A constitutively open potassium channel formed by KCNQ1 and KCNE3.
Schroeder, B.C. and Waldegger, S. and Fehr, S. and Bleich, M. and Warth, R. and Greger, R. and Jentsch, T.J.
Nature 403 (6766): 196-199. 13 January 2000


Two subsets of memory T lymphocytes with distinct homing potentials and effector functions.
Sallusto, F. and Lenig, D. and Foerster, R. and Lipp, M. and Lanzavecchia, A.
Nature 401 (6754): 708-712. 14 October 1999

Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP.
Yeung, K. and Seitz, T. and Li, S.F. and Janosch, P. and McFerran, B. and Kaiser, C. and Fee, F. and Katsanakis, K.D. and Rose, D.W. and Mischak, H. and Sedivy, J.M. and Kolch, W.
Nature 401 (6749): 173-177. 9 September 1999

The mahogany protein is a receptor involved in suppression of obesity.
Nagle, D.L. and McGrail, S.H. and Vitale, J. and Wolf, E.A. and Dussault, B.J. and DiRocco, L. and Holmgren, L. and Montagno, J. and Bork, P. and Huszar, D. and Fairchild-Huntress, V. and Ge, P. and Keilty, J. and Ebeling, C. and Baldini, L. and Gilchrist, J. and Burn, P. and Carlson, G.A. and Moore, K.J.
Nature 398 : 148-152. 11 March 1999

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28.
Hutloff, A. and Dittrich, A.M. and Beier, K.C. and Eljaschewitsch, B. and Kraft, R. and Anagnostopoulos, I. and Kroczek, R.A.
Nature 397 (6716): 263-266. 21 January 1999


Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy.
Schroeder, B.C. and Kubisch, C. and Stein, V. and Jentsch, T.J.
Nature 396 (6712): 687-690. 17 December 1998

Signal transduction. Docking IkappaB kinases.
Scheidereit, C.
Nature 395 : 225-226. 17 September 1998

Csk controls antigen receptor-mediated development and selection of T-lineage cells.
Schmedt, C. and Saijo, K. and Niidome, T. and Kuehn, R. and Aizawa, S. and Tarakhovsky, A.
Nature 394 (6696): 901-904. 27 August 1998

Microdomains of GPI-anchored proteins in living cells revealed by crosslinking.
Friedrichson, T. and Kurzchalia, T.V.
Nature 394 (6695): 802-805. 20 August 1998

Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro.
Draguhn, A. and Traub, R.D. and Schmitz, D. and Jefferys, J.G.R.
Nature 394 (6689): 189-192. 9 July 1998

CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells.
Henn, V. and Slupsky, J.R. and Graefe, M. and Anagnostopoulos, I. and Foerster, R. and Mueller-Berghaus, G. and Kroczek, R.A.
Nature 391 (667): 591-594. 1 January 1998


Severe neuropathies in mice with targeted mutations in the ErbB3 receptor.
Riethmacher, D. and Sonnenberg-Riethmacher, E. and Brinkmann, V. and Yamaai, T. and Lewin, G.R. and Birchmeier, C.
Nature 389 (6652): 725-730. 16 October 1997

More hippocampal neurons in adult mice living in an enriched environment.
Kempermann, G. and Kuhn, H.G. and Gage, F.H.
Nature 386 (6624): 493-495. 3 April 1997

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation.
Plemper, R.K. and Bohmler, S. and Bordallo, J. and Sommer, T. and Wolf, D.H.
Nature 388 : 891-895. 1 January 1997


Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
Weidner, K.M. and Dicesare, S. and Sachs, M. and Brinkmann, V. and Behrens, J. and Birchmeier, W.
Nature 384 (6605): 173-176. 14 November 1996

Two physically distinct pores in the dimeric ClC-0 chloride channel.
Ludewig, U. and Pusch, M. and Jentsch, T.J.
Nature 383 (6598): 340-343. 26 September 1996

The C5a chemoattractant receptor mediates mucosal defence to infection.
Hoepken, U.E. and Lu, B. and Gerard, N.P. and Gerard, C.
Nature 383 (6595): 86-89. 5 September 1996

Functional interaction of beta-catenin with the transcription factor LEF-1.
Behrens, J. and von Kries, J.P. and Kuehl, M. and Bruhn, L. and Wedlich, D. and Grosschedl, R. and Birchmeier, W.
Nature 382 (6592): 638-642. 15 August 1996

A common molecular basis for three inherited kidney stone diseases.
Lloyd, S.E. and Pearce, S.H. and Fisher, S.E. and Steinmeyer, K. and Schwappach, B. and Scheinman, S.J. and Harding, B. and Bolino, A. and Devoto, M. and Goodyer, P. and Rigden, S.P. and Wrong, O. and Jentsch, T.J. and Craig, I.W. and Thakker, R.V.
Nature 379 (6564): 445-449. 1 February 1996

Requirement of mammalian DNA polymerase-beta in base-excision repair.
Sobol, R.W. and Horton, J.K. and Kuehn, R. and Gu, H. and Singhal, R.K. and Prasad, R. and Rajewsky, K. and Wilson, S.H.
Nature 379 (6561): 183-186. 11 January 1996

Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein.
Brocke, S. and Gijbels, K. and Allegretta, M. and Ferber, I. and Piercy, C. and Blankenstein, T. and Martin, R. and Utz, U. and Karin, N. and Mitchell, D. and Veromaa, T. and Waisman, A. and Gaur, A. and Conlon, P. and Ling, N. and Fairchild, P.J. and Wraith, D.C. and Ogarra, A. and Fathman, C.G. and Steinman, L.
Nature 379 (6563): 343-346. 1 January 1996


Multiple essential functions of neuregulin in development.
Meyer, D. and Birchmeier, C.
Nature 378 (6555): 386-390. 23 November 1995

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud.
Bladt, F. and Riethmacher, D. and Isenmann, S. and Aguzzi, A. and Birchmeier, C.
Nature 376 (6543): 768-771. 31 August 1995

Scatter factor/hepatocyte growth factor is essential for liver development.
Schmidt, C. and Bladt, F. and Goedecke, S. and Brinkmann, V. and Zschiesche, W. and Sharpe, M. and Gherardi, E. and Birchmeier, C.
Nature 373 (6515): 699-702. 23 February 1995

Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion.
Pusch, M. and Ludewig, U. and Rehfeldt, A. and Jentsch, T.J.
Nature 373 (6514): 527-531. 9 February 1995

Challenging times for bioinformatics.
Casari, G. and Andrade, M.A. and Bork, P. and Daruvar, A. and Ouzounis, C. and Schneider, R. and Tamames, J. and Valencia, A. and Sander, C.
Nature 376 : 647-648. 1 January 1995

Distinct functions for the two importin subunits in nuclear protein import.
Goerlich, D. and Vogel, F. and Mills, A.D. and Hartmann, E. and Laskey, R.A.
Nature 377 : 246-248. 1 January 1995


Implications for dorsoventral axis determination from the zebrafish mutation janus.
Abdelilah, S. and Solnica-Krezel, L. and Stainier, D.Y. and Driever, W.
Nature 370 (6489): 468-471. 11 August 1994

NMDA receptors and activity-dependent tuning of the receptive fields of spinal cord neurons.
Lewin, G.R. and Mckintosh, E. and McMahon, S.B.
Nature 369 (6480): 482-485. 9 June 1994

Trinity of cation channels.
Jentsch, T.J.
Nature 367 (6462): 412-413. 3 February 1994

Evolutionary conservation of components of the protein translocation complex.
Hartmann, E. and Sommer, T. and Prehn, S. and Goerlich, D. and Jentsch, S. and Rapoport, T.A.
Nature 367 : 654-657. 1 January 1994


Universal nucleic acid-binding domain revealed by crystal structure of the B. subtilis major cold-shock protein.
Schindelin, H. and Marahiel, M.A. and Heinemann, U.
Nature 364 (6433): 164-168. 8 July 1993

Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis.
Bommert, K. and Charlton, M.P. and DeBello, W.M. and Chin, G.J. and Betz, H. and Augustine, G.J.
Nature 363 (6425): 163-165. 13 May 1993

A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice.
Schedl, A. and Montoliu, L. and Kelsey, G. and Schutz, G.
Nature 362 (6417): 258-261. 18 March 1993

Qa-2 molecules are peptide receptors of higher stringency than ordinary class I molecules.
Roetzschke, O. and Falk, K. and Stevanovic, S. and Grahovac, B. and Soloski, M.J. and Jung, G. and Rammensee, H.G.
Nature 361 (6413): 642-644. 18 February 1993

Benzodiazepine-induced motor impairment linked to point mutation in cerebellar GABAA receptor.
Korpi, E.R. and Kleingoor, C. and Kettenmann, H. and Seeburg, P.H.
Nature 361 : 356-359. 1 January 1993

A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum.
Sommer, T. and Jentsch, S.
Nature 365 : 176-179. 1 January 1993


Regions involved in the opening of CIC-2 chloride channel by voltage and cell volume.
Gruender, S. and Thiemann, A. and Pusch, M. and Jentsch, T.J.
Nature 360 (6406): 759-762. 24 December 1992

Molecular identification of the gene responsible for congenital nephrogenic diabetes insipidus.
Rosenthal, W. and Seibold, A. and Antaramian, A. and Lonergan, M. and Arthus, M.F. and Hendy, G.N. and Birnbaumer, M. and Bichet, D.G.
Nature 359 (6392): 233-235. 17 September 1992

Molecular cloning of the receptor for human antidiuretic hormone.
Birnbaumer, M. and Seibold, A. and Gilbert, S. and Ishido, M. and Barberis, C. and Antaramian, A. and Brabet, P. and Rosenthal, W.
Nature 357 (6376): 333-335. 28 May 1992

A chloride channel widely expressed in epithelial and non-epithelial cells.
Thiemann, A. and Gruender, S. and Pusch, M. and Jentsch, T.J.
Nature 356 (6364): 57-60. 5 March 1992

What's in a genome?
Bork, P. and Ouzounis, C. and Sander, C. and Scharf, M. and Schneider, R. and Sonnhammer, E.
Nature 358 : 287. 1 January 1992

A protein of the endoplasmic reticulum involved early in polypeptide translocation.
Goerlich, D. and Hartmann, E. and Prehn, S. and Rapoport, T.A.
Nature 357 : 47-52. 1 January 1992

Signal sequence identified.
Hartmann, E. and Rapoport, T.A. and Prehn, S.
Nature 358 : 198. 1 January 1992

Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappaB.
Wulczyn, F.G. and Naumann, M. and Scheidereit, C.
Nature 358 (6387): 597-599. 1 January 1992


Inactivation of muscle chloride channel by transposon insertion in myotonic mice.
Steinmeyer, K. and Klocke, R. and Ortland, C. and Gronemeier, M. and Jockusch, H. and Gruender, S. and Jentsch, T.J.
Nature 354 (6351): 304-308. 28 November 1991

Primary structure and functional expression of a developmentally regulated skeletal muscle chloride channel.
Steinmeyer, K. and Ortland, C. and Jentsch, T.J.
Nature 354 (6351): 301-304. 28 November 1991

Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats.
Hilbert, P. and Lindpaintner, K. and Beckmann, J.S. and Serikawa, T. and Soubrier, F. and Dubay, C.J. and Cartwright, P. and De Gouyon, B. and Julier, C. and Takahashi, S. and Vincent, M. and Ganten, D. and Georges, M. and Lathrop, G.M.
Nature 353 (6344): 521-529. 10 October 1991

Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents.
Kleuss, C. and Hescheler, J. and Ewel, C. and Rosenthal, W. and Schultz, G. and Wittig, B.
Nature 353 (6339): 43-48. 5 September 1991

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene.
Kitamura, D. and Roes, J. and Kuehn, R. and Rajewsky, K.
Nature 350 (6317): 423-426. 4 April 1991

Protein translocation. A bacterium catches up.
Rapoport, T.A.
Nature 349 : 107-108. 1 January 1991


Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes.
Jentsch, T.J. and Steinmeyer, K. and Schwarz, G.
Nature 348 (6301): 510-514. 6 December 1990


The GTP-binding protein, Go, regulates neuronal calcium channels.
Hescheler, J. and Rosenthal, W. and Trautwein, W. and Schultz, G.
Nature 325 (6103): 445-447. 29 January 1987

This list was generated on Sat Oct 20 02:34:44 2018 CEST.
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