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LRRC8/VRAC volume-regulated anion channels are crucial for hearing.
Knecht, D.A., Zeziulia, M., Bhavsar, M., Puchkov, D., Maier, H. and Jentsch, T.J.
Journal of Biological Chemistry
: 107436.
4 June 2024
(In Press)
Gain-of-function variants in CLCN7 cause hypopigmentation and lysosomal storage disease.
Polovitskaya, M.M., Rana, T., Ullrich, K., Murko, S., Bierhals, T., Vogt, G., Stauber, T., Kubisch, C., Santer, R. and Jentsch, T.J.
Journal of Biological Chemistry
: 107437.
3 June 2024
(In Press)
Cardioprotective properties of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids.
Kranrod, J., Konkel, A., Valencia, R., Darwesh, A., Fischer, R., Schunck, W.H. and Seubert, J.M.
Journal of Biological Chemistry 300
(6): 107372.
June 2024
Monitoring mitochondrial translation by pulse SILAC.
Imami, K., Selbach, M. and Ishihama, Y.
Journal of Biological Chemistry 299
(2): 102865.
February 2023
Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
Marino, S.F., Jerke, U., Rolle, S., Daumke, O. and Kettritz, R.
Journal of Biological Chemistry 298
(3): 101598.
March 2022
Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage.
Bubb, K., Holzer, T., Nolte, J.L., Krüger, M., Wilson, R., Schlötzer-Schrehardt, U., Brinckmann, J., Altmüller, J., Aszodi, A., Fleischhauer, L., Clausen-Schaumann, H., Probst, K. and Brachvogel, B.
Journal of Biological Chemistry 297
(4): 101224.
October 2021
Cellular basis of ClC-2 Cl(-) channel-related brain and testis pathologies.
Göppner, C., Soria, A.H., Hoegg-Beiler, M.B. and Jentsch, T.J.
Journal of Biological Chemistry 296
: 100074.
4 January 2021
Ion transporter NKCC1, modulator of neurogenesis in murine olfactory neurons.
Haering, C., Kanageswaran, N., Bouvain, P., Scholz, P., Altmüller, J., Becker, C., Gisselmann, G., Wäring-Bischof, J. and Hatt, H.
Journal of Biological Chemistry 290
(15): 9767-9779.
4 January 2021
11,12-Epoxyeicosatrienoic acid-induced inhibition of FOXO factors promotes endothelial proliferation by down-regulating p27(Kip1).
Potente, M., Fisslthaler, B., Busse, R. and Fleming, I.
Journal of Biological Chemistry 278
(32): 29619-29625.
4 January 2021
Cytochrome P450 2C9-induced endothelial cell proliferation involves induction of mitogen-activated protein (MAP) kinase phosphatase-1, inhibition of the c-Jun N-terminal kinase, and up-regulation of cyclin D1.
Potente, M., Michaelis, U.R., Fisslthaler, B., Busse, R. and Fleming, I.
Journal of Biological Chemistry 277
(18): 15671-15676.
4 January 2021
Pantoea stewartii WceF is a glycan biofilm modifying enzyme with a bacteriophage tailspike-like fold.
Irmscher, T., Roske, Y., Gayk, I., Dunsing, V., Chiantia, S., Heinemann, U. and Barbirz, S.
Journal of Biological Chemistry 296
: 100286.
2021
HIV-1 Gag release from yeast reveals ESCRT interaction with the Gag N-terminal protein region.
Meusser, B., Purfuerst, B. and Luft, F.C.
Journal of Biological Chemistry 295
(52): 17950-17972.
25 December 2020
N-acetylglucosamine drives myelination by triggering oligodendrocyte precursor cell differentiation.
Sy, M., Brandt, A.U., Lee, S.U., Newton, B. L., Pawling, J., Golzar, A., Rahman, A.A., Yu, Z., Cooper, G., Scheel, M., Paul, F., Dennis, J.W. and Demetriou, M.
Journal of Biological Chemistry 295
(51): 17413-17424.
18 December 2020
Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations.
Zhao, W., Bohleber, S., Schmidt, H., Seeher, S., Howard, M.T., Braun, D., Arndt, S., Reuter, U., Wende, H., Birchmeier, C., Fradejas-Villar, N. and Schweizer, U.
Journal of Biological Chemistry 294
(39): 14185-14200.
27 September 2019
Time-resolved DNA release from an O-antigen specific Salmonella bacteriophage with a contractile tail.
Broeker, N.K., Roske, Y., Valleriani, A., Stephan, M.S., Andres, D., Koetz, J., Heinemann, U. and Barbirz, S.
Journal of Biological Chemistry 294
(31): 11751-11761.
2 August 2019
Lysosomal proteome analysis reveals that CLN3-defective cells have multiple enzyme deficiencies associated with changes in intracellular trafficking.
Schmidtke, C., Tiede, S., Thelen, M., Käkelä, R., Jabs, S., Makrypidi, G., Sylvester, M., Schweizer, M., Braren, I., Brocke-Ahmadinejad, N., Cotman, S.L., Schulz, A., Gieselmann, V. and Braulke, T.
Journal of Biological Chemistry 294
(24): 9592-9604.
14 June 2019
Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses.
Kosciuczuk, E.M., Mehrotra, S., Saleiro, D., Kroczynska, B., Majchrzak-Kita, B., Lisowski, P., Driehaus, C., Rogalska, A., Turner, A., Lienhoop, T., Gius, D., Fish, E.N., Vassilopoulos, A. and Platanias, L.C.
Journal of Biological Chemistry 294
(3): 827-837.
18 January 2019
LRRC8 amino-termini influence pore properties and gating of volume-regulated VRAC anion channels.
Zhou, P., Polovitskaya, M.M. and Jentsch, T.J.
Journal of Biological Chemistry 293
(35): 13440-13451.
31 August 2018
Consequences of cathepsin C inactivation on membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
Seren, S., Rashed Abouzaid, M., Eulenberg-Gustavus, C., Hirschfeld, J., Soliman, H., Jerke, U., N'Guessan, K., Dallet-Choisy, S., Lesner, A., Lauritzen, C., Schacher, B., Eickholz, Pe., Nagy, N., Szell, M., Croix, C., Viaud-Massuard, M.C., Al Farraj Aldosari, A., Ragunatha, S., Ibrahim Mostafa, M., Giampieri, F., Battino, M., Cornillier, H., Lorette, G., Stephan, J.L., Goizet, C., Pedersen, J., Gauthier, F., Jenne, D.E., Marchand-Adam, S., Chapple, I.L., Kettritz, R. and Korkmaz, B.
Journal of Biological Chemistry 293
(32): 12415-12428.
10 August 2018
Activation of Smoothened in the Hedgehog pathway unexpectedly increases Gα(s)-dependent cAMP levels in Drosophila.
Praktiknjo, S.D., Saad, F., Maier, D., Ip, P. and Hipfner, D.R.
Journal of Biological Chemistry 293
(35): 13496-13508.
August 2018
LRRC8/VRAC anion channels are required for late stages of spermatid development in mice.
Lück, J.C., Puchkov, D., Ullrich, F. and Jentsch, T.J.
Journal of Biological Chemistry 293
(30): 11796-11808.
27 July 2018
Ca(2+)-activated Cl(-) currents in the murine vomeronasal organ enhance neuronal spiking but are dispensable for male-male aggression.
Münch, J., Billig, G., Huebner, C.A., Leinders-Zufall, T., Zufall, F. and Jentsch, T.J.
Journal of Biological Chemistry 293
(26): 10392-10403.
29 June 2018
Effects of allelic variations in the human myxovirus resistance protein A on its antiviral activity.
Graf, L., Dick, A., Sendker, F., Barth, E., Marz, M., Daumke, O. and Kochs, G.
Journal of Biological Chemistry 293
(9): 3056-3072.
2 March 2018
The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice.
Pelz, L., Purfürst, B. and Rathjen, F.G.
Journal of Biological Chemistry 292
(52): 21490-21503.
29 December 2017
Loss of the Na(+)/H(+) exchanger NHE8 causes male infertility in mice by disrupting acrosome formation.
Oberheide, K., Puchkov, D. and Jentsch, T.J.
Journal of Biological Chemistry 292
(26): 10845-10854.
30 June 2017
Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
Gillissen, B., Richter, A., Richter, A., Preissner, R., Schulze-Osthoff, K., Essmann, F. and Daniel, P.T.
Journal of Biological Chemistry 292
(16): 6478-6492.
21 April 2017
Aggregation of full length immunoglobulin light chains from AL amyloidosis patients is remodeled by epigallocatechin-3-gallate.
Andrich, K., Hegenbart, U., Kimmich, C., Kedia, N., Bergen, H.R., Schönland, S., Wanker, E.E. and Bieschke, J.
Journal of Biological Chemistry 292
(6): 2328-2344.
10 February 2017
Structural characterization and ligand/inhibitor identification provide functional insights into the mycobacterium tuberculosis cytochrome P450 CYP126A1.
Chenge, J.T., Duyet, L.V., Swami, S., McLean, K.J., Kavanagh, M.E., Coyne, A.G., Rigby, S.E.J., Cheesman, M.R., Girvan, H.M., Levy, C.W., Rupp, B., von Kries, J.P., Abell, C., Leys, D. and Munro, A.W.
Journal of Biological Chemistry 292
(4): 1310-1329.
27 January 2017
The A-kinase anchoring protein (AKAP) glycogen synthase kinase 3β interaction protein (GSKIP) regulates β-catenin through its interactions with both protein kinase A (PKA) and GSK3β.
Dema, A., Schröter, M.F., Perets, E., Skroblin, P., Moutty, M.C., Deàk, V.A., Birchmeier, W. and Klussmann, E.
Journal of Biological Chemistry 291
(37): 19618-19630.
9 September 2016
Amyloid-β(1-42) aggregation initiates its cellular uptake and cytotoxicity.
Jin, S., Kedia, N., Illes-Toth, E., Haralampiev, I., Prisner, S., Herrmann, A., Wanker, E.E. and Bieschke, J.
Journal of Biological Chemistry 291
(37): 19590-19606.
9 September 2016
Electrophysiological signature of homomeric and heteromeric glycine receptor channels.
Raltschev, C., Hetsch, F., Winkelmann, A., Meier, J.C. and Semtner, M.
Journal of Biological Chemistry 291
(34): 18030-18040.
19 August 2016
Inactivation and anion selectivity of volume-regulated VRAC channels depend on carboxy-terminal residues of the first extracellular loop.
Ullrich, F., Reincke, S.M., Voss, F.K., Stauber, T. and Jentsch, T.J.
Journal of Biological Chemistry 291
(33): 17040-17048.
12 August 2016
Lysosomal dysfunction caused by cellular accumulation of silica nanoparticles.
Schuetz, I., Lopez-Hernandez, T., Gao, Q., Puchkov, D., Jabs, S., Nordmeyer, D., Schmudde, M., Ruehl, E., Graf, C.M. and Haucke, V.
Journal of Biological Chemistry 291
(27): 14170-14184.
1 July 2016
A complex of Htm1 and the oxidoreductase Pdi1 accelerates degradation of misfolded glycoproteins.
Pfeiffer, A., Stephanowitz, H., Krause, E., Volkwein, C., Hirsch, C., Jarosch, E. and Sommer, T.
Journal of Biological Chemistry 291
(23): 12195-12207.
3 June 2016
Subunit-selective NMDA receptor signaling through BRAG1 and BRAG2 during synapse maturation.
Elagabani, M.N., Briševac, D., Kintscher, M., Pohle, J., Köhr, G., Schmitz, D. and Kornau, H.C.
Journal of Biological Chemistry 291
(17): 9105-9118.
22 April 2016
KCNQ potassium channels modulate sensitivity of skin D-hair mechanoreceptors.
Schütze, S., Orozco, I.J. and Jentsch, T.J.
Journal of Biological Chemistry 291
(11): 5566-5575.
11 March 2016
Poly(ADP-ribosyl)ation of Methyl CpG binding domain protein 2 regulates chromatin structure.
Becker, A., Zhang, P., Allmann, L., Meilinger, D., Bertulat, B., Eck, D., Hofstaetter, M., Bartolomei, G., Hottiger, M.O., Schreiber, V., Leonhardt, H. and Cardoso, M.C.
Journal of Biological Chemistry 291
(10): 4873-4881.
4 March 2016
The A-kinase anchoring protein GSKIP regulates GSK3β activity and controls palatal shelf fusion in mice.
Deák, V.A., Skroblin, P., Dittmayer, C., Knobeloch, K.P., Bachmann, S. and Klussmann, E.
Journal of Biological Chemistry 291
(2): 681-690.
8 January 2016
miR-184 regulates pancreatic β-cell function according to glucose metabolism.
Tattikota, S.G., Rathjen, T., Hausser, J., Khedkar, A., Kabra, U.D., Pandey, V.K., Sury, M.D., Wessels, H.H., Mollet, I.G., Eliasson, L., Selbach, M., Zinzen, R.P., Zavolan, M., Kadener, S., Tschöp, M., Jastroch, M., Friedländer, M.R. and Poy, M.N.
Journal of Biological Chemistry 290
(33): 20284-20294.
14 August 2015
Role of nucleotide binding and GTPase domain dimerization in dynamin-like myxovirus resistance protein A for GTPase activation and antiviral activity.
Dick, A., Graf, L., Olal, D., von der Malsburg, A., Gao, S., Kochs, G. and Daumke, O.
Journal of Biological Chemistry 290
(20): 12779-12792.
15 May 2015
Regulation of sarcoplasmic reticulum Ca(2+) ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2.
Ahmad, F., Shen, W., Vandeput, F., Szabo-Fresnais, N., Krall, J., Degerman, E., Goetz, F., Klussmann, E., Movsesian, M. and Manganiello, V.
Journal of Biological Chemistry 290
(11): 6763-6776.
13 March 2015
Protein kinase Ymr291w/Tda1 is essential for glucose signaling in Saccharomyces cerevisiae on the level of hexokinase isoenzyme ScHxk2 phosphorylation.
Kaps, S., Kettner, K., Migotti, R., Kanashova, T., Krause, U., Roedel, G., Dittmar, G. and Kriegel, T.M.
Journal of Biological Chemistry 290
(10): 6243-6255.
6 March 2015
Disassembly of Lys11- and mixed-linkage polyubiquitin conjugates provide insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.
Mansour, W., Nakasone, M.A., von Delbrück, M., Yu, Z., Krutauz, D., Reis, N., Kleifeld, O., Sommer, T., Fushman, D. and Glickman, M.H.
Journal of Biological Chemistry 290
(8): 4688-4704.
20 February 2015
Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation.
Horbelt, D., Boergermann, J.H., Chaikuad, A., Alfano, I., Williams, E., Lukonin, I., Timmel, T., Bullock, A.N. and Knaus, P.
Journal of Biological Chemistry 290
(6): 3390-3404.
6 February 2015
The Src Homology and Collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development.
Mlih, M., Host, L., Martin, S., Niederhoffer, N., Monassier, L., Terrand, J., Messaddeq, N., Radke, M., Gotthardt, M., Bruban, V., Kober, F., Bernard, M., Canet-Soulas, E., Abt-Jijon, F., Boucher, P. and Matz, R.L.
Journal of Biological Chemistry 290
(4): 2419-2430.
23 January 2015
Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP.
Gray, E.J., Petsalaki, E., James, D.A., Bagshaw, R.D., Stacey, M.M., Rocks, O., Gingras, A.C. and Pawson, T.
Journal of Biological Chemistry 289
(51): 35397-35408.
19 December 2014
Structural identification of the VPS18 β-propeller reveals a critical role in the HOPS complex stability and function.
Behrmann, H., Lürick, A., Kuhlee, A., Kleine Balderhaar, H., Bröcker, C., Kümmel, D., Engelbrecht-Vandré, S., Gohlke, U., Raunser, S., Heinemann, U. and Ungermann, C.
Journal of Biological Chemistry 289
(48): 33503-33512.
28 November 2014
The E3-ubiquitin ligase MID1 catalyzes ubiquitination and cleavage of Fu.
Schweiger, S., Dorn, S., Fuchs, M., Köhler, A., Matthes, F., Müller, E.C., Wanker, E., Schneider, R. and Krauß, S.
Journal of Biological Chemistry 289
(46): 31805-31817.
14 November 2014
Ca(2+)-mediated mitochondrial ROS metabolism augments Wnt/β-catenin pathway activation to facilitate cell differentiation.
Rharass, T., Lemcke, H., Lantow, M., Kuznetsov, S.A., Weiss, D.G. and Panáková, D.
Journal of Biological Chemistry 289
(40): 27937-27951.
3 October 2014
Shutdown of achaete-scute homolog-1 expression by heterogeneous nuclear ribonucleoprotein (hnRNP)-A2/B1 in hypoxia.
Kasim, M., Benko, E., Winkelmann, A., Mrowka, R., Staudacher, J.J., Persson, P.B., Scholz, H., Meier, J.C. and Fahling, M.
Journal of Biological Chemistry 289
(39): 26973-26988.
26 September 2014
Neurolysin knockout mice generation and initial phenotype characterization.
Cavalcanti, D.M.L.P., Castro, L.M., Rosa Neto, J.C., Seelaender, M., Neves, R.X., Oliveira, V., Forti, F.L., Iwai, L.K., Gozzo, F.C., Todiras, M., Schadock, I., Barros, C.C., Bader, M. and Ferro, E.S.
Journal of Biological Chemistry 289
(22): 15426-15440.
30 May 2014
Annexin A2 mediates apical trafficking of renal Na(+)-K(+)-2Cl(-)-cotransporter.
Dathe, C., Daigeler, A.L., Seifert, W., Jankowski, V., Mrowka, R., Kalis, R., Wanker, E., Mutig, K., Bachmann, S. and Paliege, A.
Journal of Biological Chemistry 289
(14): 9983-9997.
4 April 2014
Common gating of both CLC subunits underlies voltage-dependent activation of the 2Cl(-)/1H(+) exchanger ClC-7/Ostm1.
Ludwig, C.F., Ullrich, F., Leisle, L., Stauber, T. and Jentsch, T.J.
Journal of Biological Chemistry 288
(40): 28611-28619.
4 October 2013
Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities.
Ebel, P., Vom Dorp, K., Petrasch-Parwez, E., Zlomuzica, A., Kinugawa, K., Mariani, J., Minich, D., Ginkel, C., Welcker, J., Degen, J., Eckhardt, M., Dere, E., Doermann, P. and Willecke, K.
Journal of Biological Chemistry 288
(29): 21433-21447.
19 July 2013
The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells.
Sharma, A., Diecke, S., Zhang, W.Y., Lan, F., He, C., Mordwinkin, N.M., Chua, K.F. and Wu, J.C.
Journal of Biological Chemistry 288
(25): 18439-47.
21 June 2013
β2 integrin-mediated cell-cell contact transfers active myeloperoxidase from neutrophils to endothelial cells.
Jerke, U., Rolle, S., Purfürst, B., Luft, F.C., Nauseef, W.M. and Kettritz, R.
Journal of Biological Chemistry 288
(18): 12910-12919.
3 May 2013
Potentiation of the transient receptor potential vanilloid 1 channel contributes to pruritogenesis in a rat model of liver disease.
Belghiti, M., Estevez-Herrera, J., Gimenez-Garzo, C., Gonzalez-Usano, A., Montoliu, C., Ferrer-Montiel, A., Felipo, V. and Planells-Cases, R.
Journal of Biological Chemistry 288
(14): 9675-9685.
5 April 2013
Vestibular role of KCNQ4 and KCNQ5 K(+) channels revealed by mouse models.
Spitzmaul, G., Tolosa, L., Winkelman, B.H.J., Heidenreich, M., Frens, M.A., Chabbert, C., de Zeeuw, C.I. and Jentsch, T.J.
Journal of Biological Chemistry 288
(13): 9334-9344.
29 March 2013
Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.
Wang, D., Höing, S., Patterson, H.C., Ahmad, U.M., Rathinam, V.A.K., Rajewsky, K., Fitzgerald, K.A. and Golenbock, D.T.
Journal of Biological Chemistry 288
(7): 4594-4601.
15 February 2013
Mechanism for targeting the A-kinase anchoring protein AKAP18δ to the membrane.
Horner, A., Goetz, F., Tampe, R., Klussmann, E. and Pohl, P.
Journal of Biological Chemistry 287
(51): 42495-42501.
14 December 2012
Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin.
Halff, E.F., Diebolder, C.A., Versteeg, M., Schouten, A., Brondijk, T.H.C. and Huizinga, E.G.
Journal of Biological Chemistry 287
(46): 38460-38472.
9 November 2012
p14ARF-induced apoptosis in p53-deficient cells is mediated by the BH3-only protein independent de-repression of Bak through down-regulation of Mcl-1 and Bcl-xL.
Muer, A., Overkamp, T., Gillissen, B., Richter, A., Pretzsch, T., Milojkovic, A., Doerken, B., Daniel, P.T. and Hemmati, P.
Journal of Biological Chemistry 287
(21): 17343-17352.
18 May 2012
Regulation of karyopherin alpha1 and nuclear import by mammalian target of rapamycin.
Fielhaber, J.A., Tan, J., Joung, K.B., Attias, O., Huegel, S., Bader, M., Roux, P.P. and Kristof, A.S.
Journal of Biological Chemistry 287
(18): 14325-14335.
27 April 2012
Membrane topology and intracellular processing of cyclin M2 (CNNM2).
de Baaij, J.H.F., Stuiver, M., Meij, I.C., Lainez, S., Kopplin, K., Venselaar, H., Mueller, D., Bindels, R.J.M. and Hoenderop, J.G.J.
Journal of Biological Chemistry 287
(17): 13644-13655.
20 April 2012
Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex.
Hanna, J., Schütz, A., Zimmermann, F., Behlke, J., Sommer, T. and Heinemann, U.
Journal of Biological Chemistry 287
(11): 8633-8640.
9 March 2012
Identification of membrane-bound variant of metalloendopeptidase neurolysin (EC 3.4.24.16) as the non-AT1, non-AT2 angiotensin binding site.
Wangler, N.J., Santos, K.L., Schadock, I., Hagen, F.K., Escher, E., Bader, M., Speth, R.C. and Karamyan, V.T.
Journal of Biological Chemistry 287
(1): 114-122.
2 January 2012
Inhibition of the biosynthesis of the human endothelin B receptor by the cyclodepsipeptide cotransin.
Westendorf, C., Schmidt, A., Coin, I., Furkert, J., Ridelis, I., Zampatis, D., Rutz, C., Wiesner, B., Rosenthal, W., Beyermann, M. and Schuelein, R.
Journal of Biological Chemistry 286
(41): 35588-35600.
14 October 2011
From molecular details of the interplay between transmembrane helices of the thyrotropin receptor to general aspects of signal transduction in family a G-protein-coupled receptors (GPCRs).
Kleinau, G., Hoyer, I., Kreuchwig, A., Haas, A.K., Rutz, C., Furkert, J., Worth, C.L., Krause, G. and Schülein, R.
Journal of Biological Chemistry 286
(29): 25859-25871.
22 July 2011
The yeast plasma membrane ABC transporter Aus1: Purification, characterization and effect of lipids on its activity.
Marek, M., Milles, S., Schreiber, G., Daleke, D.L., Dittmar, G., Herrmann, A., Mueller, P. and Pomorski, T.G.
Journal of Biological Chemistry 286
(24): 21835-21843.
17 June 2011
Cytokine-induced paracrystals prolong the activity of signal transducers and activators of transcription (STAT) and provide a model for the regulation of protein solubility by small ubiquitin-like modifier (SUMO).
Droescher, M., Begitt, A., Marg, A., Zacharias, M. and Vinkemeier, U.
Journal of Biological Chemistry 286
(21): 18731-18746.
27 May 2011
Interaction of the influenza A virus polymerase PB2 C-terminal region with importin α isoforms provides insights into host adaptation and polymerase assembly.
Boivin, S. and Hart, D.J.
Journal of Biological Chemistry 286
(12): 10439-10448.
25 March 2011
Small molecule AKAP/PKA interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes.
Christian, F., Szaszak, M., Friedl, S., Drewianka, S., Lorenz, D., Goncalves, A., Furkert, J., Vargas, C., Schmieder, P., Goetz, F., Zuehlke, K., Moutty, M., Goettert, H., Joshi, M., Reif, B., Haase, H., Morano, I., Grossmann, S., Klukovits, A., Verli, J., Gaspar, R., Noack, C., Bergmann, M., Kass, R., Hampel, K., Kashin, D., Genieser, H.G., Herberg, F.W., Willoughby, D., Cooper, D.M., Baillie, G.S., Houslay, M.D., von Kries, J.P., Zimmermann, B., Rosenthal, W. and Klussmann, E.
Journal of Biological Chemistry 286
(11): 9079-9096.
18 March 2011
A novel inhibitory domain of Helicobacter pylori protein CagA reduces CagA effects on host cell biology.
Pelz, C., Steininger, S., Weiss, C., Coscia, F. and Vogelmann, R.
Journal of Biological Chemistry 286
(11): 8999-9008.
18 March 2011
Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation.
Jerke, U., Rolle, S., Dittmar, G., Bayat, B., Santoso, S., Sporbert, A., Luft, F.C. and Kettritz, R.
Journal of Biological Chemistry 286
(9): 7070-7081.
4 March 2011
Intrarenal renin angiotensin system revisited: role of megalin-dependent endocytosis along the proximal nephron.
Pohl, M., Kaminski, H., Castrop, H., Bader, M., Himmerkus, N., Bleich, M., Bachmann, S. and Theilig, F.
Journal of Biological Chemistry 285
(53): 41935-41946.
31 December 2010
Crystal structure of hexokinase KlHxk1 of Kluyveromyces lactis: a molecular basis for understanding the control of yeast hexokinase functions via covalent modification and oligomerization.
Kuettner, E.B., Kettner, K., Keim, A., Svergun, D.I., Volke, D., Singer, D., Hoffmann, R., Mueller, E.C., Otto, A., Kriegel, T.M. and Straeter, N.
Journal of Biological Chemistry 285
(52): 41019-41033.
24 December 2010
Sorting motifs of the endosomal/lysosomal CLC chloride transporters.
Stauber, T. and Jentsch, T.J.
Journal of Biological Chemistry 285
(45): 34537-34548.
5 November 2010
Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of omega-3 fatty acids.
Arnold, C., Markovic, M., Blossey, K., Wallukat, G., Fischer, R., Dechend, R., Konkel, A., von Schacky, C., Luft, F.C., Mueller, D.N., Rothe, M. and Schunck, W.H.
Journal of Biological Chemistry 285
(43): 32720-32733.
22 October 2010
The pseudo signal peptide of the corticotropin-releasing factor receptor type 2a decreases receptor expression and prevents Gi-mediated inhibition of adenylyl cyclase activity.
Schulz, K., Rutz, C., Westendorf, C., Ridelis, I., Vogelbein, S., Furkert, J., Schmidt, A., Wiesner, B. and Schuelein, R.
Journal of Biological Chemistry 285
(43): 32878-32887.
22 October 2010
Identification of tubulin deglutamylase among Caenorhabditis elegans and mammalian cytosolic carboxypeptidases (CCPs).
Kimura, Y., Kurabe, N., Ikegami, K., Tsutsumi, K., Konishi, Y., Kaplan, O.I., Kunitomo, H., Iino, Y., Blacque, O.E. and Setou, M.
Journal of Biological Chemistry 285
(30): 22936-22941.
23 July 2010
The late endosomal CLC-6 mediates proton/chloride countertransport in heterologous plasma membrane expression.
Neagoe, I., Stauber, T., Fidzinski, P., Bergsdorf, E.Y. and Jentsch, T.J.
Journal of Biological Chemistry 285
(28): 21689-21697.
9 July 2010
Role of CLC-5 in renal endocytosis is unique among CLC exchangers and does not require py-motif-dependent ubiquitylation.
Rickheit, G., Wartosch, L., Schaffer, S., Stobrawa, S., Novarino, G., Weinert, S. and Jentsch, T.J.
Journal of Biological Chemistry 285
(23): 17595-17603.
4 June 2010
Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal (stromal) stem cells through canonical Wnt signaling and C/EBP.
Qiu, W., Hu, Y., Andersen, T.E., Jafari, A., Li, N., Chen, W. and Kassem, M.
Journal of Biological Chemistry 285
(19): 14438-14449.
7 May 2010
Identification of a linear epitope in sortilin that partakes in pro-neurotrophin binding.
Andersen, O.S., Boisguerin, P., Glerup, S., Skeldal, S., Volkmer, R., Willnow, T.E., Nykjaer, A. and Andersen, O.M.
Journal of Biological Chemistry 285
(16): 12210-12222.
16 April 2010
Disruption of the K+ channel beta-subunit KCNE3 reveals an important role in intestinal and tracheal Cl- transport.
Preston, P., Wartosch, L., Guenzel, D., Fromm, M., Kongsuphol, P., Ousingsawat, J., Kunzelmann, K., Barhanin, J., Warth, R. and Jentsch, T.J.
Journal of Biological Chemistry 285
(10): 7165-7175.
5 March 2010
Glycogen synthase kinase 3β interaction protein functions as an A-kinase anchoring protein.
Hundsrucker, C., Skroblin, P., Christian, F., Zenn, M., Popara, V., Joshi, M., Eichhorst, J., Wiesner, B., Herberg, F.W., Reif, B., Rosenthal, W. and Klussmann, E.
Journal of Biological Chemistry 285
(8): 5507-5521.
19 February 2010
Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1.
Lausen, J., Pless, O., Leonard, F., Kuvardina-Bolling, O.N., Koch, B. and Leutz, A.
Journal of Biological Chemistry 285
(8): 5338-5346.
19 February 2010
Nuclear localization of the p75 neurotrophin receptor intracellular domain.
Parkhurst, C.N., Zampieri, N. and Chao, M.V.
Journal of Biological Chemistry 285
(8): 5361-5368.
19 February 2010
Molecular basis for association of PIPKI gamma-p90 with clathrin adaptor AP-2.
Kahlfeldt, N., Vahedi-Faridi, A., Koo, S.J., Schaefer, J.G., Krainer, G., Keller, S., Saenger, W., Krauss, M. and Haucke, V.
Journal of Biological Chemistry 285
(4): 2734-2749.
22 January 2010
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation.
Lutz, A.K., Exner, N., Fett, M.E., Schlehe, J.S., Kloos, K., Laemmermann, K., Brunner, B., Kurz-Drexler, A., Vogel, F., Reichert, A.S., Bouman, L., Vogt-Weisenhorn, D., Wurst, W., Tatzelt, J., Haass, C. and Winklhofer, K.F.
Journal of Biological Chemistry 284
(34): 22938-22951.
21 August 2009
Residues important for nitrate/proton coupling in plant and mammalian CLC transporters.
Bergsdorf, E.Y., Zdebik, A.A. and Jentsch, T.J.
Journal of Biological Chemistry 284
(17): 11184-11193.
24 April 2009
MEK1 binds directly to βarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization.
Meng, D., Lynch, M.J., Huston, E., Beyermann, M., Eichhorst, J., Adams, D.R., Klussmann, E., Houslay, M.D. and Baillie, G.S.
Journal of Biological Chemistry 284
(17): 11425-1135.
24 April 2009
Translational regulation of the human achaete-scute homologue-1 (hASH1) by fragile x-mental retardation protein (FMRP).
Faehling, M., Mrowka, R., Steege, A., Kirschner, K.M., Benko, E., Foerstera, B., Persson, P.B., Thiele, B.J., Meier, J.C. and Scholz, H.
Journal of Biological Chemistry 284
(7): 4255-4266.
13 February 2009
Cell entry of arginine-rich peptides is independent of endocytosis.
Ter-Avetisyan, G., Tünnemann, G., Nowak, D., Nitschke, M., Herrmann, A., Drab, M. and Cardoso, M.C.
Journal of Biological Chemistry 284
(6): 3370-3378.
6 February 2009
Specific TRPC6 channel activation, a novel approach to stimulate keratinocyte differentiation.
Mueller, M., Essin, K., Hill, K., Beschmann, H., Rubant, S., Schempp, C.M., Gollasch, M., Boehncke, W.H., Harteneck, C., Mueller, W.E.G. and Leuner, K.
Journal of Biological Chemistry 283
(49): 33942-33954.
5 December 2008
G9a-mediated lysine methylation alters the function of CCAAT/enhancer-binding protein-beta.
Pless, O., Kowenz-Leutz, E., Knoblich, M., Lausen, J., Beyerman, M., Walsh, M.J. and Leutz, A.
Journal of Biological Chemistry 283
(39): 26357-26363.
26 September 2008
Splice-specific functions of gephyrin in molybdenum cofactor biosynthesis.
Smolinsky, B., Eichler, S.A., Burchmeier, S., Meier, J.C. and Schwarz, G.
Journal of Biological Chemistry 283
(25): 17370-17379.
20 June 2008
Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis.
Rohe, M., Carlo, A.S., Breyhan, H., Sporbert, A., Militz, D., Schmidt, V., Wozny, C., Harmeier, A., Erdmann, B., Bales, K.R., Wolf, S.A., Kempermann, G., Paul, S.M., Schmitz, D., Bayer, T.A., Willnow, T.E. and Andersen, O.M.
Journal of Biological Chemistry 283
(21): 14826-14834.
23 May 2008
Interaction of syntenin-1 and the NG2 proteoglycan in migratory oligodendrocyte precursor cells.
Chatterjee, N., Stegmueller, J., Schaetzle, P., Karram, K., Koroll, M., Werner, H.B., Nave, K.A. and Trotter, J.
Journal of Biological Chemistry 283
(13): 8310-8317.
28 March 2008
Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy.
Murtaza, I., Wang, H.X., Feng, X., Alenina, N., Bader, M., Prabhakar, B.S. and Li, P.F.
Journal of Biological Chemistry 283
(10): 5996-6004.
7 March 2008
Determinants of anion-proton coupling in mammalian endosomal CLC proteins.
Zdebik, A.A., Zifarelli, G., Bergsdorf, E.Y., Soliani, P., Scheel, O., Jentsch, T.J. and Pusch, M.
Journal of Biological Chemistry 283
(7): 4219-4227.
15 February 2008
AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity.
Ferguson, B.J., Alexander, C., Rossi, S.W., Liiv, I., Rebane, A., Worth, C.L., Wong, J., Laan, M., Peterson, P., Jenkinson, E.J., Anderson, G., Scott, H.S., Cooke, A. and Rich, T.
Journal of Biological Chemistry 283
(3): 1723-1731.
18 January 2008
SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1.
Schmidt, V., Sporbert, A., Rohe, M., Reimer, T., Rehm, A., Andersen, O.M. and Willnow, T.E.
Journal of Biological Chemistry 282
(45): 32956-32964.
9 November 2007
Signal-responsiveness of Ikappa B kinases is determined by Cdc37-assisted transient interaction with Hsp90.
Hinz, M., Broemer, M., Coel Arslan, S., Otto, A., Mueller, E.C., Dettmer, R. and Scheidereit, C.
Journal of Biological Chemistry 282
(44): 32311-32319.
2 November 2007
The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein.
Mistry, A.C., Mallick, R., Froehlich, O., Klein, J.D., Rehm, A., Chen, G. and Sands, J.M.
Journal of Biological Chemistry 282
(41): 30097-30106.
12 October 2007
Atrial glutathione content, calcium current, and contractility.
Carnes, C.A., Janssen, P.M.L., Ruehr, M.L., Nakayama, H., Nakayama, T., Haase, H., Bauer, J.A., Chung, M.K., Fearon, I.M., Gillinov, A.M., Hamlin, R.L. and van Wagoner, D.R.
Journal of Biological Chemistry 282
(38): 28063-28073.
21 September 2007
Beta2-integrins and acquired glycoprotein IIb/IIIa (GPIIb/IIIa) receptors cooperate in NF-kappaB activation of human neutrophils.
Salanova, B., Choi, M., Rolle, S., Wellner, M., Luft, F.C. and Kettritz, R.
Journal of Biological Chemistry 282
(38): 27960-27969.
21 September 2007
Rescue of a nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutant by cell-penetrating peptides.
Oueslati, M., Hermosilla, R., Schoenenberger, E., Oorschot, V., Beyermann, M., Wiesner, B., Schmidt, A., Klumperman, J., Rosenthal, W. and Schuelein, R.
Journal of Biological Chemistry 282
(28): 20676-20685.
13 July 2007
TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain.
Urra, S., Escudero, C.A., Ramos, P., Lisbona, F., Allende, E., Covarrubias, P., Parraguez, J.I., Zampieri, N., Chao, M.V., Annaert, W. and Bronfman, F.C.
Journal of Biological Chemistry 282
(10): 7606-7615.
9 March 2007
A novel glycine receptor beta subunit splice variant predicts an unorthodox transmembrane topology: Assembly into heteromeric receptor complexes.
Oertel, J., Villmann, C., Kettenmann, H., Kirchhoff, F. and Becker, C.M.
Journal of Biological Chemistry 282
(5): 2798-2807.
2 February 2007
Crystal structure of human inosine triphosphatase: Substrate binding and implication of the itpa deficiency mutation p32T.
Stenmark, P., Kursula, P., Flodin, S., Graeslund, S., Landry, R., Nordlund, P. and Schueler, H.
Journal of Biological Chemistry 282
(5): 3182-3187.
2 February 2007
Small organic compounds enhance antigen-loading of class II MHC proteins by targeting the polymorphic P1 pocket.
Hoepner, S., Dickhaut, K., Hofstätter, M., Kraemer, H., Rueckerl, D., Soederhaell, J.A., Gupta, S., Marin-Esteban, V., Kuehne, R., Freund, C., Jung, G., Falk, K. and Roetzschke, O.
Journal of Biological Chemistry 281
(50): 38535-38542.
15 December 2006
Physical and functional interaction of the p14ARF tumor suppressor with ribosomes.
Rizos, H., McKenzie, H.A., Ayub, A.L., Woodruff, S., Becker, T.M., Scurr, L.L., Stahl, J. and Kefford, R.F.
Journal of Biological Chemistry 281
(49): 38080-38088.
8 December 2006
Functional domains of human tryptophan hydroxylase 2 (hTPH2).
Carkaci-Salli, N., Flanagan, J.M., Martz, M.K., Salli, U., Walther, D.J., Bader, M. and Vrana, K.E.
Journal of Biological Chemistry 281
(38): 28105-28112.
22 September 2006
The corticotropin-releasing factor receptor type 2a contains an N-terminal pseudo signal peptide.
Rutz, C., Renner, A., Alken, M., Schulz, K., Beyermann, M., Wiesner, B., Rosenthal, W. and Schuelein, R.
Journal of Biological Chemistry 281
(34): 24910-24921.
25 August 2006
The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion.
Roepke, T.K., Anantharam, A., Kirchhoff, P., Busque, S.M., Young, J.B., Geibel, J.P., Lerner, D.J. and Abbott, G.W.
Journal of Biological Chemistry 281
(33): 23740-23747.
18 August 2006
Cell cycle-controlled interaction of nucleolin with the retinoblastoma protein and cancerous cell transformation.
Grinstein, E., Shan, Y., Karawajew, L., Snijders, P.J., Meijer, C.J., Royer, H.D. and Wernet, P.
Journal of Biological Chemistry 281
(31): 22223-22235.
4 August 2006
The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.
Frese, S., Schubert, W.D., Findeis, A.C., Marquardt, T., Roske, Y.S., Stradal, T.E. and Heinz, D.W.
Journal of Biological Chemistry 281
(26): 18236-18245.
30 June 2006
Mitochondrial membrane potential is dependent on the oligomeric state of F1F0-ATP synthase supracomplexes.
Bornhoevd, C., Vogel, F., Neupert, W. and Reichert, A.S.
Journal of Biological Chemistry 281
(20): 13990-13998.
19 May 2006
GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins.
Kupzig, S., Deaconescu, D., Bouyoucef, D., Walker, S.A., Liu, Q., Polte, C.L., Daumke, O., Ishizaki, T., Lockyer, P.J., Wittinghofer, A. and Cullen, P.J.
Journal of Biological Chemistry 281
(15): 9891-900.
14 April 2006
DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis.
Bhonde, M.R., Hanski, M.L., Budczies, J., Cao, M., Gillissen, B., Moorthy, D., Simonetta, F., Scheruebl, H., Truss, M., Hagemeier, C., Mewes, H.W., Daniel, P.T., Zeitz, M. and Hanski, C.
Journal of Biological Chemistry 281
: 8675-8685.
31 March 2006
Crystal structure of NblA from Anabaena sp. PCC 7120, a small protein playing a key role in phycobilisome degradation.
Bienert, R., Baier, K., Volkmer, R., Lockau, W. and Heinemann, U.
Journal of Biological Chemistry 281
(8): 5216-5223.
24 February 2006
Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis.
Essmann, F., Pohlmann, S., Gillissen, B., Daniel, P.T., Schulze-Osthoff, K. and Jaenicke, R.U.
Journal of Biological Chemistry 280
(44): 37169-37177.
4 November 2005
Extracellular application of NAADP+ induces Ca2+ signaling in astrocytes in situ.
Heidemann, A.C., Schipke, C.G. and Kettenmann, H.
Journal of Biological Chemistry 280
(42): 35630-35640.
21 October 2005
RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells.
Lynch, M.J., Baillie, G.S., Mohamed, A., Li, X., Maisonneuve, C., Klussmann, E., van Heeke, G. and Houslay, M.D.
Journal of Biological Chemistry 280
(39): 33178-33189.
30 September 2005
A critical control element for interleukin-4 memory expression in T helper lymphocytes.
Tykocinski, L.O., Hajkova, P., Chang, H.D., Stamm, T., Soezeri, O., Loehning, M., Hu-Li, J., Niesner, U., Kreher, S., Friedrich, B., Pannetier, C., Gruetz, G., Walter, J., Paul, W.E. and Radbruch, A.
Journal of Biological Chemistry 280
(31): 28177-28185.
5 August 2005
Cleavage of p75 neurotrophin receptor by alpha-secretase and gamma-secretase requires specific receptor domains.
Zampieri, N., Xu, C.F., Neubert, T.A. and Chao, M.V.
Journal of Biological Chemistry 280
(15): 14563-14571.
15 April 2005
Dual functionality of the anti-beta1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors.
Humphries, J.D., Schofield, N.R., Mostafavi-Pour, Z., Green, L.J., Garratt, A.N., Mould, A.P. and Humphries, M.J.
Journal of Biological Chemistry 280
(11): 10234-10243.
18 March 2005
Bax-dependent regulation of Bak by voltage-dependent anion channel 2.
Chandra, D., Choy, G., Daniel, P.T. and Tang, D.G.
Journal of Biological Chemistry 280
: 19051-19061.
1 January 2005
NF-κB is transported into the nucleus by importin α3 and importin α4.
Fagerlund, R., Kinnunen, L., Koehler, M., Julkunen, I. and Melen, K.
Journal of Biological Chemistry 280
(16): 15942-15951.
1 January 2005
Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes: An effect of pH.
Rose, C., Kresse, W. and Kettenmann, H.
Journal of Biological Chemistry 280
(22): 20937-20944.
1 January 2005
Mathematical analysis of hepatic high density lipoprotein transport based on quantitative imaging data.
Wuestner, D.
Journal of Biological Chemistry 280
(8): 6766-6779.
1 January 2005
Modulation of the M2 muscarinic acetylcholine receptor activity with monoclonal anti-M2 receptor antibody fragments.
Peter, J.C., Wallukat, G., Tugler, J., Maurice, D., Roegel, J.C., Briand, J.P. and Hoebeke, J.
Journal of Biological Chemistry 279
(53): 55697-55706.
31 December 2004
Pharmacochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors.
Wueller, S., Wiesner, B., Loeffler, A., Furkert, J., Krause, G., Hermosilla, R., Schaefer, M., Schuelein, R., Rosenthal, W. and Oksche, A.
Journal of Biological Chemistry 279
(45): 47254-47263.
5 November 2004
Plasmodium induces swelling-activated ClC-2 anion channels in the host erythrocyte.
Huber, S.M., Duranton, C., Henke, G., Van De Sand, C., Heussler, V., Shumilina, E., Sandu, C.D., Tanneur, V., Brand, V., Kasinathan, R.S., Lang, K.S., Kremsner, P.G., Huebner, C.A., Rust, M.B., Dedek, K., Jentsch, T.J. and Lang, F.
Journal of Biological Chemistry 279
(40): 41444-41452.
1 October 2004
The microglia-activating potential of thrombin: The protease is not involved in the induction of proinflammatory cytokines and chemokines.
Hanisch, U.K., van Rossum, D., Xie, Y., Gast, K., Misselwitz, R., Ariola, S., Goldsteins, G., Koistinaho, J., Kettenmann, H. and Moeller, T.
Journal of Biological Chemistry 279
(50): 51880-51887.
27 September 2004
'Chemical analogues' of HLA-DM can induce a peptide-receptive state in HLA-DR molecules.
Marin-Esteban, V., Falk, K. and Roetzschke, O.
Journal of Biological Chemistry 279
(49): 50684-50690.
20 September 2004
Ligand-dependent differences in the internalization of endothelin A and endothelin B receptor heterodimers.
Gregan, B., Juergensen, J., Papsdorf, G., Furkert, J., Schaefer, M., Beyermann, M., Rosenthal, W. and Oksche, A.
Journal of Biological Chemistry 279
(26): 27679-27687.
25 June 2004
Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells.
Henn, V., Edemir, B., Stefan, E., Wiesner, B., Lorenz, D., Theilig, F., Schmitt, R., Vossebein, L., Tamma, G., Beyermann, M., Krause, E., Herberg, F.W., Valenti, G., Bachmann, S., Rosenthal, W. and Klussmann, E.
Journal of Biological Chemistry 279
(25): 26654-26665.
18 June 2004
Additional disruption of the ClC-2 Cl(-) channel does not exacerbate the cystic fibrosis phenotype of cystic fibrosis transmembrane conductance regulator mouse models.
Zdebik, A.A., Cuffe, J.E., Bertog, M., Korbmacher, C. and Jentsch, T.J.
Journal of Biological Chemistry 279
(21): 22276-22283.
21 May 2004
Inhibitors of protein kinase C (PKC) prevent activated transcription - role of events downstream of NF-κB DNA binding.
Catley, M.C., Cambridge, L.M., Nasuhara, Y., Ito, K., Chivers, J.E., Beaton, A., Holden, N.S., Bergmann, M.W., Barnes, P.J. and Newton, R.
Journal of Biological Chemistry 279
(18): 18457-18466.
30 April 2004
Calcium current in rat cardiomyocytes is modulated by the carboxyl-terminal ahnak domain.
Alvarez, J., Hamplova, J., Hohaus, A., Morano, I., Haase, H. and Vassort, G.
Journal of Biological Chemistry 279
(13): 12456-12461.
26 March 2004
Tyrosine radical formation in the reaction of wild type and mutant cytochrome P450cam with peroxy acids: A multifrequency EPR study of intermediates on the millisecond time scale.
Schuenemann, V., Lendzian, F., Jung, C., Contzen, J., Barra, A.L., Sligar, S.G. and Trautwein, A.X.
Journal of Biological Chemistry 279
(12): 10919-10930.
19 March 2004
Aquaporin-1, nothing but a water channel.
Tsunoda, S.P., Wiesner, B., Lorenz, D., Rosenthal, W. and Pohl, P.
Journal of Biological Chemistry 279
(12): 11364-11367.
19 March 2004
Integrins and cytokines activate nuclear transcription factor-κB in human neutrophils.
Kettritz, R., Choi, M., Rolle, S., Wellner, M. and Luft, F.C.
Journal of Biological Chemistry 279
(4): 2657-2665.
23 January 2004
Expression of nodal, lefty-A, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3.
Besser, D.
Journal of Biological Chemistry 279
(43): 45076-45084.
1 January 2004
Thermodynamic and structural analysis of peptide- and allele-dependent properties of two HLA-B27 subtypes exhibiting differential disease association.
Hillig, R.C., Huelsmeyer, M., Saenger, W., Welfle, K., Misselwitz, R., Welfle, H., Kozerski, C., Volz, A., Uchanska-Ziegler, B. and Ziegler, A.
Journal of Biological Chemistry 279
(1): 652-663.
1 January 2004
TNAP, a novel repressor of NF-kappaB-inducing kinase, suppresses NF-kappaB activation.
Hu, W.H., Mo, X.M., Walters, W.M., Brambilla, R. and Bethea, J.R.
Journal of Biological Chemistry 279
(34): 35975-35983.
1 January 2004
The interaction of protein kinase C isozymes α, ι, and θ with the cytoplasmic domain of L-selectin is modulated by phosphorylation of the receptor.
Kilian, K., Dernedde, J., Mueller, E.C., Bahr, I. and Tauber, R.
Journal of Biological Chemistry 279
(33): 34472-34480.
1 January 2004
The CCAAT enhancer-binding protein alpha (C/EBPalpha) requires a SWI/SNF complex for proliferation arrest.
Mueller, C., Calkhoven, C.F., Sha, X.J. and Leutz, A.
Journal of Biological Chemistry 279
(8): 7353-7358.
1 January 2004
AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1 - Involvement in the nuclear import of RNA-binding protein HuR.
Wang, W.G., Yang, X.L., Kawai, T., de Silanes, I.L., Mazan-Mamczarz, K., Chen, P.L., Chook, Y.M., Quensel, C., Koehler, M. and Gorospe, M.
Journal of Biological Chemistry 279
(46): 48376-48388.
1 January 2004
Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin - A potential mechanism for loss of huntingtin function in Huntington's disease.
Busch, A., Engemann, S., Lurz, R., Okazawa, H., Lehrach, H. and Wanker, E.E.
Journal of Biological Chemistry 278
(42): 41452-41461.
17 October 2003
Formation of critical oligomers is a key event during conformational transition of recombinant Syrian hamster prion protein.
Sokolowski, F., Modler, A.J., Masuch, R., Zirwer, D., Baier, M., Lutsch, G., Moss, D.A., Gast, K. and Naumann, D.
Journal of Biological Chemistry 278
(42): 40481-40492.
17 October 2003
Aminophospholipids have no access to the luminal side of the biliary canaliculus - Implications for the specific lipid composition of the bile fluid.
Tannert, A., Wuestner, D., Bechstein, J., Mueller, P., Devaux, P.F. and Herrmann, A.
Journal of Biological Chemistry 278
(42): 40631-40639.
17 October 2003
The unique hexokinase of Kluyveromyces lactis - Molecular and functional characterization and evaluation of a role in glucose signaling.
Baer, D., Golbik, R., Huebner, G., Lilie, H., Mueller, E.C., Naumann, M., Otto, A., Reuter, R., Breunig, K.D. and Kriegel, T.M.
Journal of Biological Chemistry 278
(41): 39280-39286.
10 October 2003
β-catenin is required for specification of proximal/distal cell fate during lung morphogenesis.
Mucenski, M.L., Wert, S.E., Nation, J.M., Loudy, D.E., Huelsken, J., Birchmeier, W., Morrisey, E.E. and Whitsett, J.A.
Journal of Biological Chemistry 278
(41): 40231-40238.
10 October 2003
scFv single chain antibody variable fragment as inverse agonist of the β(2) -adrenergic receptor.
Peter, J.C., Eftekhari, P., Billiald, P., Wallukat, G. and Hoebeke, J.
Journal of Biological Chemistry 278
(38): 36740-36747.
19 September 2003
Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs.
Olsen, S.K, Garbi, M., Zampieri, N., Eliseenkova, A.V., Ornitz, D.M., Goldfarb, M. and Mohammadi, M.
Journal of Biological Chemistry 278
(36): 34226-34236.
5 September 2003
Importin α nuclear localization signal binding sites for STAT1, STAT2, and influenza a virus nucleoprotein.
Melen, K., Fagerlund, R., Franke, J., Koehler, M., Kinnunen, L. and Julkunen, I.
Journal of Biological Chemistry 278
(30): 28193-28200.
25 July 2003
Design and characterization of a hybrid miniprotein that specifically inhibits porcine pancreatic elastase.
Hilpert, K., Wessner, H., Schneider-Mergener, J., Welfle, K., Misselwitz, R., Welfle, H., Hocke, A.C., Hippenstiel, S. and Hoehne, W.
Journal of Biological Chemistry 278
(27): 24986-24993.
4 July 2003
Essential role of the apolipoprotein E receptor-2 in sperm development.
Andersen, O.M., Yeung, C.H., Vorum, H., Wellner, M., Andreassen, T.K., Erdmann, B., Mueller, E.C., Herz, J., Otto, A., Cooper, T.G. and Willnow, T.E.
Journal of Biological Chemistry 278
(26): 23989-23995.
27 June 2003
The vesicular monoamine content regulates VMAT2 activity through G α(q) mouse platelets - evidence for autoregulation of vesicular transmitter update.
Holtje, M., Winter, S., Walther, D., Pahner, I., Hortnagl, H., Ottersen, O.P., Bader, M. and Ahnert-Hilger, G.
Journal of Biological Chemistry 278
(18): 15850-15858.
2 May 2003
Independent and cooperative activation of chromosomal c-fos promoter by STAT3.
Yang, E., Lerner, L., Besser, D. and Darnell, J.E.
Journal of Biological Chemistry 278
(18): 15794-15799.
2 May 2003
Identification and characterization of the autophosphorylation sites of phosphoinositide 3-kinase isoforms beta and gamma.
Czupalla, C., Culo, M., Mueller, E.C., Brock, C., Reusch, H.P., Spicher, K., Krause, E. and Nuernberg, B.
Journal of Biological Chemistry 278
(13): 11536-11545.
28 March 2003
Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1-and Sp3-dependent activation of two proximal GC-rich promoter elements.
Schaefer, G., Cramer, T., Suske, G., Kemmner, W., Wiedenmann, B. and Hoecker, M.
Journal of Biological Chemistry 278
(10): 8190-8198.
7 March 2003
Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure.
Gotthardt, M., Hammer, R.E., Hübner, N., Monti, J., Witt, C.C., McNabb, M., Richardson, J.A., Granzier, H., Labeit, S. and Herz, J.
Journal of Biological Chemistry 278
(8): 6059-6065.
21 February 2003
Phosphorylation-dependent down-regulation of c-Myb DNA binding is abrogated by a point mutation in the v-myb oncogene.
Andersson, K.B., Kowenz-Leutz, E., Brendeford, E.M., Tygsett, A.H.H., Leutz, A. and Gabrielsen, O.S.
Journal of Biological Chemistry 278
(6): 3816-3824.
7 February 2003
The tailspike protein of Shigella phage Sf6 - A structural homolog of Salmonella phage p22 tailspike protein without sequence similarity in the beta-helix domain.
Freiberg, A., Morona, R., Van den Bosch, L., Jung, C., Behlke, J., Carlin, N., Seckler, R. and Baxa, U.
Journal of Biological Chemistry 278
(3): 1542-1548.
17 January 2003
The Golgi protein RCAS1 controls cell surface expression of tumor-associated O-linked glycan antigens.
Engelsberg, A., Hermosilla, R., Karsten, U., Schuelein, R., Doerken, B. and Rehm, A.
Journal of Biological Chemistry 278
(25): 22998-23007.
1 January 2003
Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA.
Herlan, M., Vogel, F., Boernhovd, C., Neupert, W. and Reichert, A.S.
Journal of Biological Chemistry 278
(30): 27781-27788.
1 January 2003
YB-1 as a cell cycle-regulated transcription factor facilitating cyclin A and cyclin B1 gene expression.
Juerchott, K., Bergmann, S., Stein, U., Walther, W., Janz, M., Manni, I., Piaggio, G., Fietze, E., Dietel, M. and Royer, H.D.
Journal of Biological Chemistry 278
(30): 27988-27996.
1 January 2003
Lithostathine quadruple-helical filaments form proteinase K-resistant deposits in Creutzfeldt-Jakob disease.
Laurine, E., Gregoire, C., Faendrich, M., Engemann, S., Marchal, S., Thion, L., Mohr, M., Monsarrat, B., Michel, B., Dobson, C.M., Wanker, E.E., Erard, M. and Verdier, J.M.
Journal of Biological Chemistry 278
(51): 51770-51778.
1 January 2003
Decreased liver fatty acid binding capacity and altered liver lipid distribution in mice lacking the liver fatty acid-binding protein gene.
Martin, G.G., Danneberg, H., Kumar, L.S., Atshaves, B.P., Erol, E., Bader, M., Schroeder, F. and Binas, B.
Journal of Biological Chemistry 278
(24): 21429-21438.
1 January 2003
Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance.
Most, P., Remppis, A., Pleger, S.T., Loeffler, E., Ehlermann, P., Bernotat, J., Kleuss, C., Heierhorst, J., Ruiz, P., Witt, H., Karczewski, P., Mao, L., Rockman, H.A., Duncan, S.J., Katus, H.A. and Koch, W.J.
Journal of Biological Chemistry 278
(36): 33809-33817.
1 January 2003
RNA-structural mimicry in Escherichia coli ribosomal protein L4-dependent regulation of the S10 operon.
Stelzl, U., Zengel, J.M., Tovbina, M., Walker, M., Nierhaus, K.H., Lindahl, L. and Patel, D.J.
Journal of Biological Chemistry 278
(30): 28237-28245.
1 January 2003
Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol.
Avvakumov, G.V., Grishkovskaya, I., Muller, Y.A. and Hammond, G.L.
Journal of Biological Chemistry 277
(47): 45219-45225.
22 November 2002
The extracellular N terminus of the endothelin B (ETB) receptor is cleaved by a metalloprotease in an agonist-dependent process.
Grantcharova, E., Furkert, J., Reusch, H.P., Krell, H.W., Papsdorf, G., Beyermann, M., Schulein, R., Rosenthal, W. and Oksche, A.
Journal of Biological Chemistry 277
(46): 43933-43941.
15 November 2002
The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor.
Muller, Y.A., Heiring, C., Misselwitz, R., Welfle, K. and Welfle, H.
Journal of Biological Chemistry 277
(45): 43410-43416.
8 November 2002
Proteomic analysis reveals alterations in the renal kallikrein pathway during hypoxia-induced hypertension.
Thongboonkerd, V., Gozal, E., Sachleben, L.R., Arthur, J.M., Pierce, W.M., Cai, J., Chao, J., Bader, M., Pesquero, J.B., Gozal, D. and Klein, J.B.
Journal of Biological Chemistry 277
(38): 34708-34716.
20 September 2002
Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition.
Izsvak, Z., Khare, D., Behlke, J., Heinemann, U., Plasterk, R.H. and Ivics, Z.
Journal of Biological Chemistry 277
(37): 34581-34588.
13 September 2002
Steroid ligands bind human sex hormone-binding globulin in specific orientations and produce distinct changes in protein conformation.
Grishkovskaya, I., Avvakumov, G.V., Hammond, G.L., Catalano, M.G. and Muller, Y.A.
Journal of Biological Chemistry 277
(35): 32086-32093.
30 August 2002
Expression of the human poliovirus Receptor/CD155 gene is activated by sonic hedgehog.
Solecki, D.J., Gromeier, M., Mueller, S., Bernhardt, G. and Wimmer, E.
Journal of Biological Chemistry 277
(28): 25697-25702.
12 July 2002
Calcium/Calmodulin-dependent protein kinase IIdelta2 and gamma insoforms regulate potassium currents of rat brain capillary endothelial cells under hypoxic conditions.
Balla, Z., Hoch, B., Karczewski, P. and Blasig, I.E.
Journal of Biological Chemistry 277
(24): 21306-21314.
14 June 2002
Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae.
Boucher, P., Liu, P., Gotthardt, M., Hiesberger, T., Anderson, R.G. and Herz, J.
Journal of Biological Chemistry 277
: 15507-15513.
3 May 2002
The signal peptide of the G protein-coupled human endothelin B receptor is necessary for translocation of the N-terminal tail across the endoplasmic reticulum membrane.
Koechl, R., Alken, M., Rutz, C., Krause, G., Oksche, A., Rosenthal, W. and Schuelein, R.
Journal of Biological Chemistry 277
(18): 16131-16138.
3 May 2002
Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuehn is perturbed by stimulation of Lef-1/β-catenin signaling.
Wong, M.H., Huelsken, J., Birchmeier, W. and Gordon, J.I.
Journal of Biological Chemistry 277
(18): 15843-15850.
3 May 2002
Asymmetric photocross-linking pattern of restriction endonuclease EcoRII to the DNA recognition sequence.
Muecke, M., Pingoud, V., Grelle, G., Kraft, R., Krueger, D.H. and Reuter, M.
Journal of Biological Chemistry 277
(16): 14288-14293.
19 April 2002
Rap-specific GTPase activating protein follows an alternative mechanism.
Brinkmann, T., Daumke, O., Herbrand, U., Kühlmann, D., Stege, P., Ahmadian, M.R. and Wittinghofer, A.
Journal of Biological Chemistry 277
(15): 12525-31.
12 April 2002
Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo.
Selbach, M., Moese, S., Hauck, C.R., Meyer, T.F. and Backert, S.
Journal of Biological Chemistry 277
(9): 6775-6778.
1 March 2002
Novel pathogenic mechanisms of congenital insensitivity to pain with anhidrosis genetic disorder unveiled by functional analysis of neurotrophic tyrosine receptor kinase type 1/nerve growth factor receptor mutations.
Miranda, C., Di Virgilio, M., Selleri, S., Zanotti, G., Pagliardini, S., Pierotti, M.A. and Greco, A.
Journal of Biological Chemistry 277
(8): 6455-6462.
22 February 2002
The conserved Mynd domain of BS69 binds cellular and oncoviral proteins through a common PXLXP motif.
Ansieau, S. and Leutz, A.
Journal of Biological Chemistry 277
(7): 4906-4910.
1 January 2002
An Src homology 3-like domain is responsible for dimerization of the repressor protein KorB encoded by the promiscuous IncP plasmid RP4.
Delbrueck, H., Ziegelin, G., Lanka, E. and Heinemann, U.
Journal of Biological Chemistry 277
(6): 4191-4198.
1 January 2002
Ligand exchange of major histocompatibility complex class II proteins is triggered by H-bond donor groups of small molecules.
Falk, K., Lau, J.M., Santambrogio, L., Esteban, V.M., Puentes, F., Roetzschke, O. and Strominger, J.L.
Journal of Biological Chemistry 277
(4): 2709-2715.
1 January 2002
Purification and characterization of the human Elongator complex.
Hawkes, N.A., Otero, G., Winkler, G.S., Marshall, N., Dahmus, M.E., Krappmann, D., Scheidereit, C., Thomas, C.L., Schiavo, G., Erdjument-Bromage, H., Tempst, P. and Svejstrup, J.Q.
Journal of Biological Chemistry 277
(4): 3047-3052.
1 January 2002
YB-1 relocates to the nucleus in adenovirus-infected cells and facilitates viral replication by inducing E2 gene expression through the E2 late promoter.
Holm, P.S., Bergmann, S., Juerchott, K., Lage, H., Brand, K., Ladhoff, A., Mantwill, K., Curiel, D.T., Dobbelstein, M., Dietel, M., Gaensbacher, B. and Royer, H.D.
Journal of Biological Chemistry 277
(12): 10427-10434.
1 January 2002
Surface expression and endocytosis of the human cytomegalovirus-encoded chemokine receptor US28 is regulated by agonist-independent phosphorylation.
Mokros, T., Rehm, A., Droese, J., Oppermann, M., Lipp, M. and Höpken, U.E.
Journal of Biological Chemistry 277
(47): 45122-45128.
1 January 2002
Megalin deficiency offers protection from renal aminoglycoside accumulation.
Schmitz, C., Hilpert, J., Jacobsen, C., Boensch, C., Christensen, E.I., Luft, F.C. and Willnow, T.E.
Journal of Biological Chemistry 277
: 618-622.
1 January 2002
A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast.
Stade, K., Vogel, F., Schwienhorst, I., Meusser, B., Volkwein, C., Nentwig, B., Dohmen, R.J. and Sommer, T.
Journal of Biological Chemistry 277
(51): 49554-49561.
1 January 2002
Urokinase-dependent human vascular smooth muscle cell adhesion requires selective vitronectin phosphorylation by ectoprotein kinase CK2.
Stepanova, V., Jerke, U., Sagach, V., Lindschau, C., Dietz, R., Haller, H. and Dumler, I.
Journal of Biological Chemistry 277
: 10265-10272.
1 January 2002
The phosphoglucose isomerase from the hyperthermophilic archaeon Pyrococcus furiosus is a unique glycolytic enzyme that belongs to the cupin superfamily.
Verhees, C.H., Huynen, M.A., Ward, D.E., Schiltz, E., de Vos, W.M. and van der Oost, J.
Journal of Biological Chemistry 276
(44): 40926-40932.
2 November 2001
Protein kinase C regulates the phosphorylation and cellular localization of occludin.
Andreeva, A.Y., Krause, E., Mueller, E.C., Blasig, I.E. and Utepbergenov, D.I.
Journal of Biological Chemistry 276
(42): 38480-38486.
19 October 2001
The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2.
Michelsen, K.S., Aicher, A., Mohaupt, M., Hartung, T., Dimmeler, S., Kirschning, C.J. and Schumann, R.R.
Journal of Biological Chemistry 276
(28): 25680-25686.
13 July 2001
An inhibitory role of Rho in the vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells.
Klussmann, E., Tamma, G., Lorenz, D., Wiesner, B., Maric, K., Hofmann, F., Aktories, K., Valenti, G. and Rosenthal, W.
Journal of Biological Chemistry 276
(23): 20451-20457.
8 June 2001
An internalization signal in ClC-5, an endosomal Cl-channel mutated in dent's disease.
Schwake, M., Friedrich, T. and Jentsch, T.J.
Journal of Biological Chemistry 276
(15): 12049-12054.
13 April 2001
Functional rescue of the nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutants G185C and R202C by a second site suppressor mutation.
Schuelein, R., Zuehlke, K., Krause, G. and Rosenthal, W.
Journal of Biological Chemistry 276
(11): 8384-8392.
16 March 2001
Protein kinase B beta/Akt2 plays a specific role in muscle differentiation.
Vandromme, M., Rochat, A., Meier, R., Carnac, G., Besser, D., Hemmings, B.A., Fernandez, A. and Lamb, N.J.
Journal of Biological Chemistry 276
(11): 8173-8179.
16 March 2001
The MAPK kinase kinase TAK1 plays a central role in coupling the interleukin-1 receptor to both transcriptional and RNA-targeted mechanisms of gene regulation.
Holtmann, H., Enninga, J., Kalble, S., Thiefes, A., Dorrie, A., Broemer, M., Winzen, R., Wilhelm, A., Ninomiya-Tsuji, J., Matsumoto, K., Resch, K. and Kracht, M.
Journal of Biological Chemistry 276
: 3508-3516.
2 February 2001
Pores formed by single subunits in mixed dimers of different CLC chloride channels.
Weinreich, F. and Jentsch, T.J.
Journal of Biological Chemistry 276
(4): 2347-2353.
26 January 2001
Resolution of the human sex hormone-binding globulin dimer interface and evidence for two steroid-binding sites per homodimer.
Avvakumov, G.V., Grishkovskaya, I., Muller, Y.A. and Hammond, G.L.
Journal of Biological Chemistry 276
(37): 34453-34457.
1 January 2001
A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling.
Befort, K., Filliol, D., Decaillot, F.M., Gaveriaux-Ruff, C., Hoehe, M.R. and Kieffer, B.L.
Journal of Biological Chemistry 276
(5): 3130-3137.
1 January 2001
A two-receptor pathway for catabolism of Clara cell secretory protein in the kidney.
Burmeister, R., Boe, I.M., Nykjaer, A., Jacobsen, C., Moestrup, S.K., Verroust, P., Christensen, E.I., Lund, J. and Willnow, T.E.
Journal of Biological Chemistry 276
(16): 13295-13301.
1 January 2001
Alternative use of a mini exon of the L1 gene affects L1 binding to neural ligands.
De Angelis, E., Bruemmendorf, T., Cheng, L., Lemmon, V. and Kenwrick, S.
Journal of Biological Chemistry 276
(35): 32738-32742.
1 January 2001
Ribosomal protein S5 interacts with the internal ribosomal entry site of hepatitis C virus.
Fukushi, S., Okada, M., Stahl, J., Kageyama, T., Hoshino, F.B. and Katayama, K.
Journal of Biological Chemistry 276
(24): 20824-20826.
1 January 2001
The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity.
Koroll, M., Rathjen, F.G. and Volkmer, H.
Journal of Biological Chemistry 276
: 10646-10654.
1 January 2001
Regulation of mu-opioid receptor gene transcription by interleukin-4 and influence of an allelic variation within a STAT6 transcription factor binding site.
Kraus, J., Boerner, C., Giannini, E., Hickfang, K., Braun, H., Mayer, P., Hoehe, M.R., Ambrosch, A., Koenig, W. and Hoelt, V.
Journal of Biological Chemistry 276
(47): 43901-43908.
1 January 2001
Adrenodoxin reductase-adrenodoxin complex structure suggests electron transfer path in steroid biosynthesis.
Mueller, J.J., Lapko, A., Bourenkov, G., Ruckpaul, K. and Heinemann, U.
Journal of Biological Chemistry 276
(4): 2786-2789.
1 January 2001
Tumor necrosis factor-alpha regulates the expression of inducible costimulator receptor ligand on CD34+ progenitor cells during differentiation into antigen presenting cells.
Richter, G., Hayden-Ledbetter, M., Irgang, M., Ledbetter, J.A., Westermann, J., Koerner, I., Daemen, K., Clark, E.A., Aicher, A. and Pezzutto, A.
Journal of Biological Chemistry 276
(49): 45686-45693.
1 January 2001
CALEB binds via its acidic stretch to the fibrinogen-like domain of tenascin-C or tenascin-R and its expression is dynamically regulated after optic nerve lesion.
Schumacher, S., Jung, M., Noerenberg, U., Dorner, A., Chiquet-Ehrismann, R., Stuermer, C.A.O. and Rathjen, F.G.
Journal of Biological Chemistry 276
(10): 7337-7345.
1 January 2001
Hyperthermia-induced nuclear translocation of transcription factor YB-1 leads to enhanced expression of multidrug resistance-related ABC transporters.
Stein, U., Juerchott, K., Walther, W., Bergmann, S., Schlag, P.M. and Royer, H.D.
Journal of Biological Chemistry 276
(30): 28562-28569.
1 January 2001
Cleavage and shedding of E-cadherin after induction of apoptosis.
Steinhusen, U., Weiske, J., Badock, V., Tauber, R., Bommert, K. and Huber, O.
Journal of Biological Chemistry 276
(7): 4972-4980.
1 January 2001
Hypercontractile properties of cardiac muscle fibers in a knock-in mouse model of cardiac myosin-binding protein-C.
Witt, C.C., Gerull, B., Davies, M.J., Centner, T., Linke, W.A. and Thierfelder, L.
Journal of Biological Chemistry 276
(7): 5353-5359.
1 January 2001
Evidence for the role of megalin in renal uptake of transthyretin.
Sousa, M.M., Norden, A.G.W., Jacobsen, C., Willnow, T.E., Christensen, E.I., Thakker, R.V., Verroust, P.J., Moestrup, S.K. and Saraiva, M.J.
Journal of Biological Chemistry 275
(49): 38176-38181.
8 December 2000
A switch mechanism for Gbetagamma activation of IKACh.
Medina, I., Krapivinsky, G., Arnold, S., Kovoor, P., Krapivinsky, L. and Clapham, D.E.
Journal of Biological Chemistry 275
: 29709-29716.
22 September 2000
Steroid-binding specificity of human sex hormone-binding globulin is influenced by occupancy of a zinc-binding site.
Avvakumov, G.V., Muller, Y.A. and Hammond, G.L.
Journal of Biological Chemistry 275
(34): 25920-25925.
25 August 2000
Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.
Gotthardt, M., Trommsdorff, M., Nevitt, M.F., Shelton, J., Richardson, J.A., Stockinger, W., Nimpf, J. and Herz, J.
Journal of Biological Chemistry 275
(33): 25616-25624.
18 August 2000
The reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2.
Stockinger, W., Brandes, C., Fasching, D., Hermann, M., Gotthardt, M., Herz, J., Schneider, W.J. and Nimpf, J.
Journal of Biological Chemistry 275
(33): 25625-25632.
18 August 2000
Functional and structural analysis of ClC-K chloride channels involved in renal disease.
Waldegger, S. and Jentsch, T.J.
Journal of Biological Chemistry 275
(32): 24527-24533.
11 August 2000
KCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currents.
Schroeder, B.C., Hechenberger, M., Weinreich, F., Kubisch, C. and Jentsch, T.J.
Journal of Biological Chemistry 275
(31): 24089-24095.
4 August 2000
DNA recognition, strand selectivity, and cleavage mode during integrase family site-specific recombination.
Tribble, G., Ahn, Y.T., Lee, J., Dandekar, T. and Jayaram, M.
Journal of Biological Chemistry 275
(29): 22255-22267.
21 July 2000
Mammalian mitochondrial ribosomal proteins (4) - Amino acid sequencing, characterization, and identification of corresponding gene sequences.
O'Brien, T.W., Liu, J.G., Sylvester, J.E., Mougey, E.B., Fischel-Ghodsian, N., Thiede, B., Wittmann-Liebold, B. and Graack, H.R.
Journal of Biological Chemistry 275
(24): 18153-18159.
16 June 2000
Normal blood pressure and plasma renin activity in mice lacking the renin-binding protein, a cellular renin inhibitor.
Schmitz, C., Gotthardt, M., Hinderlich, S., Leheste, J.R., Gross, V., Vorum, H., Christensen, E.I., Luft, F.C., Takahashi, S. and Willnow, T.E.
Journal of Biological Chemistry 275
(20): 15357-15362.
19 May 2000
Mammalian Sec61 is associated with Sec62 and Sec63.
Meyer, H.A., Grau, H., Kraft, R., Kostka, S., Prehn, S., Kalies, K.U. and Hartmann, E.
Journal of Biological Chemistry 275
(19): 14550-14557.
12 May 2000
Surface expression and single channel properties of KCNQ2/KCNQ3, M-type K+ channels involved in epilepsy.
Schwake, M., Pusch, M., Kharkovets, T. and Jentsch, T.J.
Journal of Biological Chemistry 275
(18): 13343-13348.
5 May 2000
Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL.
Sakkab, D., Lewitzky, M., Posern, G., Schaeper, U., Sachs, M., Birchmeier, W. and Feller, S.M.
Journal of Biological Chemistry 275
(15): 10772-10778.
14 April 2000
Novel interaction between the transcription factor CHOP (GADD153) and the ribosomal protein FTE/S3a modulates erythropoiesis.
Cui, K.Y., Coutts, M., Stahl, J. and Sytkowski, A.J.
Journal of Biological Chemistry 275
(11): 7591-7596.
17 March 2000
The C-terminal subdomain (IF2 C-2) contains the entire fMet-tRNA binding site of initiation factor IF2.
Spurio, R., Brandi, L., Caserta, E., Pon, C.L., Gualerzi, C.O., Misselwitz, R., Krafft, C., Welfle, K. and Welfle, H.
Journal of Biological Chemistry 275
(4): 2447-2454.
28 January 2000
Cellular uptake of Clostridium botulinum C2 toxin requires oligomerization and acidification.
Barth, H., Bloecker, D., Behlke, J., Bergsma-Schutter, W., Brisson, A., Benz, R. and Aktories, K.
Journal of Biological Chemistry 275
(25): 18704-18711.
1 January 2000
Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15) - A possible link between interferon regulatory factor signaling and the COP9/signalosome.
Cohen, H., Azriel, A., Cohen, T., Meraro, D., Hashmueli, S., Bech-Otschir, D., Kraft, R., Dubiel, W. and Levi, B.Z.
Journal of Biological Chemistry 275
(50): 39081-39089.
1 January 2000
The IkappaB kinase (IKK) complex is tripartiteand contains IKKgamma but not IKAP as a regular component.
Krappmann, D., Hatada, E.N., Tegethoff, S., Li, J., Klippel, A., Giesel, K., Baeuerle, A. and Scheidereit, C.
Journal of Biological Chemistry 275
: 29779-29787.
1 January 2000
Urokinase stimulates human vascular smooth muscle cell migration via a phosphatidylinositol 3-kinase-tyk2 interaction.
Kusch, A., Tkachuk, S., Haller, H., Dietz, R., Gulba, D.C., Lipp, M. and Dumler, I.
Journal of Biological Chemistry 275
(50): 39466-39473.
1 January 2000
Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily.
Kutay, U., Hartmann, E., Treichel, N., Calado, A., Carmo-Fonseca, M., Prehn, S., Kraft, R., Goerlich, D. and Bischoff, F.R.
Journal of Biological Chemistry 275
(51): 40163-40168.
1 January 2000
Ubiquitin-mediated proteolysis of a short lived regulatory protein depends on its cellular localization.
Lenk, U. and Sommer, T.
Journal of Biological Chemistry 275
(50): 39403-39410.
1 January 2000
Imaging DNA loops induced by restriction endonuclease EcoRII. A single amino acid substitution uncouples target recognition from cooperative DNA interaction and cleavage.
Muecke, M., Lurz, R., Mackeldanz, P., Behlke, J., Krueger, D.H. and Reuter, M.
Journal of Biological Chemistry 275
(39): 30631-30637.
1 January 2000
Identification of a nuclear respiratory factor-1 binding site within the core promoter of the human polio virus receptor/CD155 gene.
Solecki, D., Bernhardt, G., Lipp, M. and Wimmer, E.
Journal of Biological Chemistry 275
(17): 12453-12462.
1 January 2000
Apoptosis-induced cleavage of beta-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential.
Steinhusen, U., Badock, V., Bauer, A., Behrens, J., Wittmann-Liebold, B., Doerken, B. and Bommert, K.
Journal of Biological Chemistry 275
(21): 16345-16353.
1 January 2000
A general approach for identification of RNA-Protein cross-linking sites within native human spliceosomal small nuclear ribonucleoproteins (snRNPs) - Analysis of RNA-protein contacts in native U1 and U4/U6.U5 snRNPs.
Urlaub, H., Hartmuth, K., Kostka, S., Grelle, G. and Luehrmann, R.
Journal of Biological Chemistry 275
(52): 41458-41468.
1 January 2000
Mammalian mitochondrial ribosomal proteins (2) - Amino acid sequencing, characterization, and identification of corresponding gene sequences.
O'Brien, T.W., Fiesler, S.E., Denslow, N.D., Thiede, B., Wittmann-Liebold, B., Mougey, E.B., Sylvester, J.E. and Graack, H.R.
Journal of Biological Chemistry 274
(51): 36043-36051.
17 December 1999
CLC chloride channels in Caenorhabditis elegans.
Schriever, A.M., Friedrich, T., Pusch, M. and Jentsch, T.J.
Journal of Biological Chemistry 274
(48): 34238-34244.
26 November 1999
A single negatively charged residue affects the orientation of a membrane protein in the inner membrane of Escherichia coli only when it is located adjacent to a transmembrane domain.
Rutz, C., Rosenthal, W. and Schuelein, R.
Journal of Biological Chemistry 274
(47): 33757-33763.
19 November 1999
Inactivation of protein-tyrosine phosphatases as mechanism of UV-induced signal transduction.
Gross, S., Knebel, A., Tenev, T., Neininger, A., Gaestel, M., Herrlich, P. and Boehmer, F.D.
Journal of Biological Chemistry 274
: 26378-26386.
10 September 1999
Urokinase induces activation and formation of stat4 and stat1-stat2 complexes in human vascular smooth muscle cells.
Dumler, I., Kopmann, A., Wagner, K., Mayboroda, O.A., Jerke, U., Dietz, R., Haller, H. and Gulba, D.C.
Journal of Biological Chemistry 274
: 24059-24065.
20 August 1999
Functional interactions of the immunoglobulin superfamily member F11 are differentially regulated by the extracellular matrix proteins tenascin-R and tenascin-C.
Zacharias, U., Noerenberg, U. and Rathjen, F.G.
Journal of Biological Chemistry 274
: 24357-24365.
20 August 1999
Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells.
Diebold, S.S., Kursa, P., Wagner, E., Cotten, M. and Zenke, M.
Journal of Biological Chemistry 274
: 19087-19094.
2 July 1999
Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress tumor necrosis factor alpha by phosphorylation.
Rogalla, T., Ehrnsperger, M., Preville, X., Kotlyarov, A., Lutsch, G., Ducasse, C., Paul, C., Wieske, M., Arrigo, A.P., Buchner, J. and Gaestel, M.
Journal of Biological Chemistry 274
(27): 18947-8956.
2 July 1999
MAPKAP kinase 2 phosphorylates serum response factor in vitro and in vivo.
Heidenreich, O., Neininger, A., Schratt, G., Zinck, R., Cahill, M.A., Engel, K., Kotlyarov, A., Kraft, R., Kostka, S., Gaestel, M. and Nordheim, A.
Journal of Biological Chemistry 274
: 14434-14443.
14 May 1999
Photoaffinity labeling and mass spectrometry identify ribosomal protein S3 as a potential target for hybrid polar cytodifferentiation agents.
Webb, Y., Zhou, X.B., Ngo, L., Cornish, V., Stahl, J., Erdjument-Bromage, H., Tempst, P., Rifkind, R.A., Marks, P.A., Breslow, R. and Richon, V.M.
Journal of Biological Chemistry 274
: 14280-14287.
14 May 1999
Megalin antagonizes activation of the parathyroid hormone receptor.
Hilpert, J., Nykjaer, A., Jacobsen, C., Wallukat, G., Nielsen, R., Moestrup, S.K., Haller, H., Luft, F.C., Christensen, E.I. and Willnow, T.E.
Journal of Biological Chemistry 274
(9): 5620-5625.
26 February 1999
Protein kinase A anchoring proteins are required for vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells.
Klussmann, E., Maric, K., Wiesner, B., Beyermann, M. and Rosenthal, W.
Journal of Biological Chemistry 274
(8): 4934-4938.
19 February 1999
Identification and characterization of the cis-acting elements of human CD155 gene core promoter.
Solecki, D., Wimmer, E., Lipp, M. and Bernhardt, G.
Journal of Biological Chemistry 274
: 1791-1800.
15 January 1999
Mutational analysis demonstrates that ClC-4 and ClC-5 directly mediate plasma membrane currents.
Friedrich, T., Breiderhoff, T. and Jentsch, T.J.
Journal of Biological Chemistry 274
(2): 896-902.
8 January 1999
Mammalian mitochondrial ribosomal proteins. N-terminal amino acid sequencing, characterization, and identification of corresponding gene sequencing.
Goldschmidt-Reisin, S., Kitakawa, M., Herfurth, E., Wittmann-Liebold, B., Grohmann, L. and Graack, H.J.
Journal of Biological Chemistry 273
(52): 34828-34836.
25 December 1998
A short DNA methyltransferase isoform restores methylation in vivo.
Gaudet, F., Talbot, D., Leonhardt, H. and Jaenisch, R.
Journal of Biological Chemistry 273
(49): 32725-32729.
4 December 1998
Oxygenation cascade in conversion of n-alkanes to alpha,omega-dioic acids catalyzed by cytochrome P450 52A3.
Scheller, U., Zimmer, T., Becher, D., Schauer, F. and Schunck, W.H.
Journal of Biological Chemistry 273
(49): 32528-32534.
4 December 1998
Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA.
Newton, R., Seybold, J., Kuitert, L.M., Bergmann, M. and Barnes, P.J.
Journal of Biological Chemistry 273
(48): 32312-32321.
27 November 1998
Downstream activation of a TATA-less promoter by Oct-2, Bob1, and NF-κB directs expression of the homing receptor BLR1 to mature B cells.
Wolf, I., Pevzner, V., Kaiser, E., Bernhardt, G., Claudio, E., Siebenlist, U., Foerster, R. and Lipp, M.
Journal of Biological Chemistry 273
(44): 28831-28836.
30 October 1998
Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line - cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.
Brockstedt, E., Rickers, A., Kostka, S., Laubersheimer, A., Doerken, B., Wittmann-Liebold, B., Bommert, K. and Otto, A.
Journal of Biological Chemistry 273
(43): 28057-28064.
23 October 1998
A heterotrimeric G protein of the Gi family is required for cAMP-triggered trafficking of aquaporin 2 in kidney epithelial cells.
Valenti, G., Procino, G., Liebenhoff, U., Frigeri, A., Benedetti, P.A., Ahnert-Hilger, G., Nuernberg, B., Svelto, M. and Rosenthal, W.
Journal of Biological Chemistry 273
(35): 22627-22634.
28 August 1998
Biochemical engineering of neural cell surfaces by the synthetic N-Propanoyl-substituted neuraminic acid precursor.
Schmidt, C., Stehling, P., Schnitzer, J., Reutter, W. and Horstkorte, R.
Journal of Biological Chemistry 273
(30): 19146-19152.
24 July 1998
Golgi localization and functionally important domains in the NH2 and COOH terminus of the yeast CLC putative chloride channel Gef1p.
Schwappach, B., Stobrawa, S., Hechenberger, M., Steinmeyer, K. and Jentsch, T.J.
Journal of Biological Chemistry 273
(24): 15110-15108.
12 June 1998
Differential expression and association of calcium channel alpha1B and beta subunits during rat brain ontogeny.
Vance, C.L., Begg, C.M., Lee, W.L., Haase, H., Copeland, T.D. and McEnery, M.W.
Journal of Biological Chemistry 273
(23): 14495-14502.
5 June 1998
Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene.
Rosen, H., Reshef, A., Maeda, N., Lippoldt, A., Shpizen, S., Triger, L., Eggertsen, G., Bjorkhem, I. and Leitersdorf, E.
Journal of Biological Chemistry 273
(24): 14805-14812.
June 1998
Induction of ceramide-mediated apoptosis by the anticancer pPhospholipid analog, hexadecylphosphocholine.
Wieder, T., Orfanos, C.E. and Geilen, C.C.
Journal of Biological Chemistry 273
(18): 11025-11031.
1 May 1998
IkappaBalpha degradation and nuclear factor-kappaB DNA binding are insufficient for interleukin-1beta and tumor necrosis factor-alpha-induced kappaB-dependent transcription. Requirement for an additional activation pathway.
Bergmann, M., Hart, L., Lindsay, M., Barnes, P.J. and Newton, R.
Journal of Biological Chemistry 273
: 6607-6610.
1 March 1998
Isozyme function of n-alkane-inducible cytochromes P450 in Candida maltosa revealed by sequential gene disruption.
Ohkuma, M., Zimmer, T., Iida, T., Schunck, W.H., Ohta, A. and Takagi, M.
Journal of Biological Chemistry 273
(7): 3948-3953.
13 February 1998
Crystal structure of barley 1,3-1,4-beta-glucanase at 2.0-A resolution and comparison with Bacillus 1,3-1,4-beta-glucanase.
Mueller, J.J., Thomsen, K.K. and Heinemann, U.
Journal of Biological Chemistry 273
(6): 3438-3446.
6 February 1998
Branched phosphatidylcholines stimulate activity of cytochrome P450SCC (CYP11A1) in phospholipid vesicles by enhancing cholesterol binding, membrane incorporation, and protein exchange.
Kisselev, P., Wessel, R., Pisch, S., Bornscheuer, U., Schmid, R.D. and Schwarz, D.
Journal of Biological Chemistry 273
(3): 1380-1386.
16 January 1998
The Jak/Stat pathway and urokinase receptor signaling inhuman aortic vascular smooth muscle cells.
Dumler, I., Weis, A., Mayboroda, O.A., Maasch, C., Jerke, U., Haller, H. and Gulba, D.C.
Journal of Biological Chemistry 273
(1): 315-321.
2 January 1998
Sustained long-term potentiation and anxiety in mice lacking the Mas protooncogene.
Walther, T., Balschun, D., Voigt, J.P., Fink, H., Zuschratter, W., Birchmeier, C., Ganten, D. and Bader, M.
Journal of Biological Chemistry 273
: 11867-11873.
1 January 1998
12-O-Tetradecanoylphorbol-13-acetate activates the Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of SOS involving serine phosphorylation of Shc in NIH3T3 cells.
El-Shemerly, M.Y., Besser, D., Nagasawa, M. and Nagamine, Y.
Journal of Biological Chemistry 272
(49): 30599-30602.
5 December 1997
Localization of O-glycosylation sites on glycopeptide fragments from lactation-associated MUC1. All putative sites within the tandem repeat are glycosylation targets in vivo.
Mueller, S., Goletz, S., Gooley, A., Lawson, A.M. and Hanisch, F.G.
Journal of Biological Chemistry 272
(40): 24780-24793.
3 October 1997
Interaction of earthworm hemolysin with lipid membranes requires sphingolipids.
Lange, S., Nuessler, F., Kauschke, E., Lutsch, G., Cooper, E.L. and Herrmann, A.
Journal of Biological Chemistry 272
(33): 20884-20892.
15 August 1997
Reconstitution of functional voltage-gated chloride channels from complementary fragments of CLC-1.
Schmidt-Rose, T. and Jentsch, T.J.
Journal of Biological Chemistry 272
(33): 20515-20521.
15 August 1997
Beta subunit heterogeneity in neuronal L-type Ca2+ channels.
Pichler, M., Cassidy, T.N., Reimer, D., Haase, H., Krause, R., Ostler, D. and Striessnig, J.
Journal of Biological Chemistry 272
(21): 13877-13882.
23 May 1997
The yeast SPC22/23 homolog SPC3p is essential for signal peptidase activity.
Meyer, H.A. and Hartmann, E.
Journal of Biological Chemistry 272
(20): 13159-13164.
16 May 1997
The mutation t315a in candida albicans sterol 14 alpha demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity.
Lamb, D.C., Kelly, D.E., Schunck, W.H., Shyadehi, A.Z., Akhtar, M., Lowe, D.J., Baldwin, B.C. and Kelly, S.L.
Journal of Biological Chemistry 272
(9): 5682-5688.
28 February 1997
Cytoskeleton reorganization induces the urokinase-type plasminogen activator gene via the Ras/extracellular signal-regulated kinase (ERK) signaling pathway.
Irigoyen, J.P., Besser, D. and Nagamine, Y.
Journal of Biological Chemistry 272
(3): 1904-1909.
17 January 1997
Specific aspects of electron transfer from adrenodoxin to cytochromes p450scc and p45011beta.
Beckert, V. and Bernhardt, R.
Journal of Biological Chemistry 272
: 4883-4888.
1 January 1997
RNA ligands selected by cleavage stimulation factor (CstF) contain distinct sequence motifs that function as downstream elements in 3' end processing of pre-mRNA.
Beyer, K., Dandekar, T. and Keller, W.
Journal of Biological Chemistry 272
: 26769-26779.
1 January 1997
Introduction of plasmid DNA into isolated mitochondria by electroporation. A novel approach toward gene correction for mitochondrial disorders.
Collombet, J.M., Wheeler, V.C., Vogel, F. and Coutelle, C.
Journal of Biological Chemistry 272
: 5342-5347.
1 January 1997
Purification, structural analysis, and function of natural atac, a cytokine secreted by cd8(+) T cells.
Dorner, B., Mueller, S., Entschladen, F., Schroeder, J.M., Frankel, P., Kraft, R., Friedl, P., Clarklewis, I. and Kroczek, R.A.
Journal of Biological Chemistry 272
: 8817-8823.
1 January 1997
Mouse brain microglia express interleukin-15 and its multimeric receptor complex functionally coupled to Janus kinase activity.
Hanisch, U.K., Lyons, S.A., Prinz, M., Nolte, C., Weber, J.R., Kettenmann, H. and Kirchhoff, F.
Journal of Biological Chemistry 272
: 28853-28860.
1 January 1997
Organization of the neurofascin gene and analysis of developmentally regulated alternative splicing.
Hassel, B., Rathjen, F.G. and Volkmer, H.
Journal of Biological Chemistry 272
: 28742-28749.
1 January 1997
Transient changes of the conformation of hemagglutinin of influenza virus at low ph detected by time resolved circular dichroism spectroscopy.
Korte, T., Ludwig, K., Krumbiegel, M., Zirwer, D., Damaschun, G. and Herrmann, A.
Journal of Biological Chemistry 272
: 9764-9770.
1 January 1997
Farnesol inhibits L-type Ca2+ channels in vascular smooth muscle cells.
Roullet, J.B., Luft, U.C., Xue, H., Chapman, J., Bychkov, R., Roullet, C.M., Luft, F.C., Haller, H. and McCarron, D.A.
Journal of Biological Chemistry 272
: 32240-32246.
1 January 1997
Cis-elements required for the demethylation of the mouse M-lysozyme downstream enhancer.
Schmitz, A., Short, M., Ammerpohl, O., Asbrand, C., Nickel, J. and Renkawitz, R.
Journal of Biological Chemistry 272
: 20850-20856.
1 January 1997
The promoters for human and monkey poliovirus receptors: requirements for basic and cell type specific activity.
Solecki, D., Schwarz, S., Wimmer, E., Lipp, M. and Bernhardt, G.
Journal of Biological Chemistry 272
: 5579-5586.
1 January 1997
Identification and sequence analysis of contact sites between ribosomal proteins and rRNA in Escherichia Coli 30S subunits by a new approach using matrix assisted laser desorption ionization mass spectrometry combined with N-terminal microsequencing.
Urlaub, H., Thiede, B., Mueller, E.C., Brimacombe, R. and Wittmann-Liebold, B.
Journal of Biological Chemistry 272
: 14547-14555.
1 January 1997
Identification of pirin, a novel highly conserved nuclear protein.
Wendler, W.M.F., Kremmer, E., Foerster, R. and Winnacker, E.L.
Journal of Biological Chemistry 272
: 8482-8489.
1 January 1997
A family of putative chloride channels from Arabidopsis and functional complementation of a yeast strain with a CLC gene disruption.
Hechenberger, M., Schwappach, B., Fischer, W.N., Frommer, W.B., Jentsch, T.J. and Steinmeyer, K.
Journal of Biological Chemistry 271
(52): 33632-33638.
27 December 1996
Structurally related spc1p and spc2p of yeast signal peptidase complex are functionally distinct.
Mullins, C., Meyer, H.A., Hartmann, E., Green, N. and Fang, H.
Journal of Biological Chemistry 271
(46): 29094-29099.
15 November 1996
Membrane targeting and determination of transmembrane topology of the human vasopressin V2 receptor.
Schuelein, R., Rutz, C. and Rosenthal, W.
Journal of Biological Chemistry 271
(46): 28844-28852.
15 November 1996
The major subunit of the asialoglycoprotein receptor is expressed on the hepatocellular surface in mice lacking the minor receptor subunit.
Braun, J.R., Willnow, T.E., Ishibashi, S., Ashwell, G. and Herz, J.
Journal of Biological Chemistry 271
(35): 21160-21166.
30 August 1996
The homologue of mammalian SPC12 is important for efficient signal peptidase activity in saccharomyces cerevisiae.
Fang, H., Panzner, S., Mullins, C., Hartmann, E. and Green, N.
Journal of Biological Chemistry 271
(28): 16460-16465.
12 July 1996
The multiple carrier model of nonribosomal peptide biosynthesis at modular multienzymatic templates.
Stein, T., Vater, J., Kruft, V., Otto, A., Wittmann-Liebold, B., Franke, P., Panico, M., McDowell, R. and Morris, H.R.
Journal of Biological Chemistry 271
(26): 15428-15435.
28 June 1996
Alpha-branched 1,2-diacyl phosphatidylcholines as effectors of activity of cytochrome P450SCC (CYP11A1). Modeling the structure of the fatty acyl chain region of cardiolipin.
Schwarz, D., Kisselev, P., Wessel, R., Jueptner, O. and Schmid, R.D.
Journal of Biological Chemistry 271
(22): 12840-12846.
31 May 1996
The mechanism of the acyl-carbon bond cleavage reaction catalyzed by recombinant sterol 14 alpha-demethylase of Candida albicans (other names are: lanosterol 14 alpha-demethylase, P-45014DM, and CYP51).
Shyadehi, A.Z., Lamb, D.C., Kelly, S.L., Kelly, D.E., Schunck, W.H., Wright, J.N., Corina, D. and Akhtar, M.
Journal of Biological Chemistry 271
(21): 12445-12450.
24 May 1996
Cell cycle regulation of nuclear factor p92 DNA binding activity by novel phase specific inhibitors.
Grinstein, E., Weinert, I., Droese, B., Pagano, M. and Royer, H.D.
Journal of Biological Chemistry 271
(16): 9215-9222.
19 April 1996
Engineering a mineralocorticoid to a glucocorticoid synthesizing cytochrome P450.
Boettner, B., Schrauber, H. and Bernhardt, R.
Journal of Biological Chemistry 271
(14): 8028-8033.
5 April 1996
Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo.
Isakoff, S., Yu, Y.P., Su, Y.P., Blaikie, P., Yajnik, V., Rose, E., Weidner, K.M., Sachs, M., Margolis, B. and Skolnik, E.
Journal of Biological Chemistry 271
(8): 3959-3962.
23 February 1996
Membrane topology of the 12- and the 25-kDa subunits of the mammalian signal peptidase complex.
Kalies, K.U. and Hartmann, E.
Journal of Biological Chemistry 271
(7): 3925-3929.
16 February 1996
Mechanisms identified in the transcriptional control of epithelial gene expression.
Hennig, G., Loewrick, O., Birchmeier, W. and Behrens, J.
Journal of Biological Chemistry 271
: 595-602.
1 January 1996
Identification of residues within the shc phosphotyrosine binding phosphotyrosine interaction domain crucial for phosphopeptide interaction.
Yajnik, V., Blaikie, P., Bork, P. and Margolis, B.
Journal of Biological Chemistry 271
(4): 1813-1816.
1 January 1996
Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease.
Steinmeyer, K., Schwappach, B., Bens, M., Vandewalle, A. and Jentsch, T.J.
Journal of Biological Chemistry 270
(52): 31172-31177.
29 December 1995
The role of threonine-54 in adrenodoxin for the properties of its iron-sulfur cluster and its electron transfer function.
Uhlmann, H. and Bernhardt, R.
Journal of Biological Chemistry 270
(50): 29959-29966.
15 December 1995
Activation and nuclear translocation of mitogen-activated protein kinases by polyomavirus middle-T or serum depend on phosphatidylinositol 3-kinase.
Urich, M., el Shemerly, M.Y., Besser, D., Nagamine, Y. and Ballmer-Hofer, K.
Journal of Biological Chemistry 270
(49): 29286-29292.
8 December 1995
Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif.
Engel, K., Schultz, H., Martin, F., Kotlyarov, A., Plath, K., Hahn, M., Heinemann, U. and Gaestel, M.
Journal of Biological Chemistry 270
(45): 27213-27221.
10 November 1995
Peptide environment of the peptidyl transferase center from Escherichia coli 70 S ribosomes as determined by thermoaffinity labeling with dihydrospiramycin.
Bischof, O., Urlaub, H., Kruft, V. and Wittmann-Liebold, B.
Journal of Biological Chemistry 270
(39): 23060-23064.
29 September 1995
Identification of a transactivation function in the progesterone receptor that interacts with the TAFII110 subunit of the TFIID complex.
Schwerk, C., Klotzbuecher, M., Sachs, M., Ulber, V. and Klein-Hitpass, L.
Journal of Biological Chemistry 270
(36): 21331-21338.
8 September 1995
Signal sequence processing in rough microsomes.
Lyko, F., Martoglio, B., Jungnickel, B., Rapoport, T.A. and Dobberstein, B.
Journal of Biological Chemistry 270
(34): 19873-19878.
25 August 1995
Organization of the alpha-globin promoter and possible role of nuclear factor i in an alpha-globin-inducible and in a noninducible cell line.
Rein, T., Foerster, R., Krause, A., Winnacker, E.L. and Zorbas, H.
Journal of Biological Chemistry 270
(33): 19643-19650.
18 August 1995
Phosphorylation of elongation factor Tu prevents ternary complex formation.
Alexander, C., Bilgin, N., Lindschau, C., Mesters, J.R., Kraal, B., Hilgenfeld, R., Erdmann, V.A. and Lippmann, C.
Journal of Biological Chemistry 270
(24): 14541-14547.
16 June 1995
Implication of mammalian ribosomal protein S3 in the processing of DNA damage.
Kim, J., Chubatsu, L.S., Admon, A., Stahl, J., Fellous, R. and Linn, S.
Journal of Biological Chemistry 270
(23): 13620-13629.
9 June 1995
Transient free radicals in iron/oxygen reconstition of mutant protein R2 Y122F.
Sahlin, M., Lassmann, G., Poetsch, S., Sjoeberg, A. and Graeslund, A.
Journal of Biological Chemistry 270
(21): 12361-12372.
26 May 1995
A mutation of angiotensinogen in a patent with preeclampsia leads to alteredkinetics of the renin-angiotensin system.
Inoue, I., Rohrwasser, A., Helin, C., Jeunemaitre, X., Crain, P., Bohlender, J., Lifton, R.P., Corvol, P., Ward, K. and Lalouel, J.M.
Journal of Biological Chemistry 270
(19): 11430-11436.
12 May 1995
Crystal structure and site-directed mutagenesis of Bacillus macerans endo-1,3-1,4-beta-glucanase.
Hahn, M., Olsen, O., Politz, O., Borriss, R. and Heinemann, U.
Journal of Biological Chemistry 270
(7): 3081-3088.
17 February 1995
Differential recognition of alpha1-antitrypsin-elastase and alpha1-antichymotrypsin-cathepsin G complexes by the low density lipoprotein receptor-related protein.
Poller, W., Willnow, T.E., Hilpert, J. and Herz, J.
Journal of Biological Chemistry 270
(6): 2841-2845.
10 February 1995
Thrombin, phorbol ester, and cAMP regulate thrombin receptor protein and mRNA expression by different pathways.
Zacharias, U., Xu, Y.C., Hagege, J., Sraer, J.D., Brass, L.F. and Rondeau, E.
Journal of Biological Chemistry 270
(2): 545-550.
13 January 1995
Characterization of the scatter factor/hepatocyte growth factor gene promoter - positive and negative regulatory elements direct gene expression to mesenchymal cells.
Plaschke-Schluetter, A., Behrens, J., Gherardi, E. and Birchmeier, W.
Journal of Biological Chemistry 270
: 830-836.
1 January 1995
Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel module - the WW domain.
Sudol, M., Bork, P., Einbond, A., Kastury, K., Druck, T., Negrini, M., Huebner, K. and Lehman, D.
Journal of Biological Chemistry 270
: 14733-14741.
1 January 1995
C1 repressor-mediated DNA looping is involved in C1 autoregulation of bacteriophage P1.
Heinzel, T., Lurz, R., Dobrinski, B., Velleman, M. and Schuster, H.
Journal of Biological Chemistry 269
(50): 31885-31890.
16 December 1994
Modulation of the beta-adrenergic response of cardiomyocytes by specific lipoxygenase products involves their incorporation into phosphatidylinositol and activation of protein kinase C.
Wallukat, G., Morwinski, R. and Kuehn, H.
Journal of Biological Chemistry 269
(46): 29055-29060.
18 November 1994
Role of innervation, excitability, and myogenic factors in the expression of the muscular chloride channel ClC-1. A study on normal and myotonic muscle.
Klocke, R., Steinmeyer, K., Jentsch, T.J. and Jockusch, H.
Journal of Biological Chemistry 269
(44): 27635-27639.
4 November 1994
C-terminal region of adrenodoxin affects its structural integrity and determines differences in its electron transfer function to cytochrome P-450.
Uhlmann, H., Kraft, R. and Bernhardt, R.
Journal of Biological Chemistry 269
(36): 22557-22564.
9 September 1994
Low density lipoprotein receptor-related protein is necessary for the internalization of both tissue-type plasminogen activator- inhibitor complexes and free tissue-type plasminogen activator.
Orth, K., Willnow, T.E., Herz, J., Gething, M.J. and Sambrook, J.
Journal of Biological Chemistry 269
(33): 21117-21122.
19 August 1994
Identification of novel ubiquitous and cell type-specific factors that specifically recognize immunoglobulin heavy and light chain promoters.
Franke, S., Scholz, G. and Scheidereit, C.
Journal of Biological Chemistry 269
(31): 20075-20082.
5 August 1994
Analysis of the puromycin finding site in the 70 S ribosome of Escherichia coli at the peptide level.
Bischof, O., Kruft, V. and Wittmann-Liebold, B.
Journal of Biological Chemistry 269
(28): 18315-18319.
15 July 1994
Molecular dissection of ligand binding sites on the low density lipoprotein receptor-related protein.
Willnow, T.E., Orth, K. and Herz, J.
Journal of Biological Chemistry 269
(22): 15827-15832.
3 June 1994
Identification of tumor-associated protein variants during rat hepatocarcinogenesis. Aldose reductase.
Zeindl-Eberhart, E., Jungblut, P., Otto, A. and Rabes, H.M.
Journal of Biological Chemistry 269
(20): 14589-14594.
20 May 1994
Cell binding and internalization by filamentous phage displaying a cyclic Arg-Gly-AsP-containing peptide.
Hart, S.L., Knight, A.M., Harbottle, R.P., Mistry, A., Hunger, H.D., Cutler, D.F., Williamson, R. and Coutelle, C.
Journal of Biological Chemistry 269
(17): 12468-12474.
29 April 1994
Generation of the soluble and functional cytosolic domain of microsomal cytochrome P450 52A3.
Scheller, U., Kraft, R., Schroeder, K.L. and Schunck, W.H.
Journal of Biological Chemistry 269
(17): 12779-12783.
29 April 1994
Tryptophan radicals formed by iron/oxygen reaction with E.coli ribonucleotide reductase protein R2 mutant Y122F.
Sahlin, M., Lassmann, G., Poetsch, S., Slaby, A., Sjoeberg, B.M. and Graeslund, A.
Journal of Biological Chemistry 269
(16): 11699-11702.
22 April 1994
Nonsense and missense mutations in the muscular chloride channel gene Clc-1 of myotonic mice.
Gronemeier, M., Condie, A., Prosser, J., Steinmeyer, K., Jentsch, T.J. and Jockusch, H.
Journal of Biological Chemistry 269
(8): 5963-5967.
25 February 1994
Mutations of tyrosine 82 in bovine adrenodoxin that affect binding to cytochromes P45011A1 and P45011B1 but not electron transfer.
Beckert, V., Dettmer, R. and Bernhardt, R.
Journal of Biological Chemistry 269
(4): 2568-2673.
28 January 1994
Phosphorylation and supramolecular organization of murine small heat shock protein HSP25 abolish its actin polymerization- inhibiting activity.
Benndorf, R., Hayess, K., Ryazantsev, S., Wieske, M., Behlke, J. and Lutsch, G.
Journal of Biological Chemistry 269
: 20780-20784.
1 January 1994
The motility signal of scatter factor /hepatocyte growth factor mediated through the receptor tyrosine kinase Met requires intracellular action of Ras.
Hartmann, G., Weidner, K.M., Schwarz, H. and Birchmeier, W.
Journal of Biological Chemistry 269
: 21936-21939.
1 January 1994
Molecular structure and expression of rat bradykinin B2 receptor gene. Evidence for alterative splicing.
Pesquero, J.B., Lindsey, C.J., Zeh, K., Paiva, A.C.M., Ganten, D. and Bader, M.
Journal of Biological Chemistry 43
: 26920-26925.
1 January 1994
Dipeptide processing activates recombinant human prochymase.
Urata, H., Karnik, S.S., Graham, R.M. and Husain, A.
Journal of Biological Chemistry 268
(32): 24318-24322.
15 November 1993
Nephrogenic diabetes insipidus. A V2 vasopressin receptor unable to stimulate adenylyl cyclase.
Rosenthal, W., Antaramian, A., Gilbert, S. and Birnbaumer, M.
Journal of Biological Chemistry 268
(18): 13030-13033.
25 June 1993
Cross-linked amino acids in the protein pairs L3-L19 and L23-L29 of Bacillus stearothermophilus ribosomes after treatment with diepoxybutane.
Herwig, S., Kruft, V., Eckart, K. and Wittmann-Liebold, B.
Journal of Biological Chemistry 268
(7): 4643-4650.
5 March 1993
Small heat shock proteins are molecular chaperones.
Jakob, U., Gaestel, M., Engel, K. and Buchner, J.
Journal of Biological Chemistry 268
(3): 1517-1520.
25 January 1993
Site-specific photocross-linking reveals that Sec61p and TRAM contact different regions of a membrane-inserted signal sequence.
High, S., Martoglio, B., Goerlich, D., Andersen, S.S.L., Ashford, A.J., Giner, A., Hartmann, E., Prehn, S., Rapoport, T.A., Dobberstein, B. and Brunner, J.
Journal of Biological Chemistry 268
: 26745-26751.
1 January 1993
Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance.
Willnow, T.E., Goldstein, J.L., Orth, K., Brown, M.S. and Herz, J.
Journal of Biological Chemistry 267
(36): 26172-26180.
25 December 1992
Spectral analysis of the protein-derived tyrosyl radicals from prostaglandin H synthase.
DeGray, J.A., Lassmann, G., Curtis, J.F., Kennedy, L.J., Marnett, L.J., Eling, T.E. and Mason, R.P.
Journal of Biological Chemistry 267
(33): 32583-23588.
25 November 1992
Dephosphorylation of the small heat shock protein HSP 25 by calcium/calmodulin-dependent (type 2B) protein phosphatase.
Gaestel, M., Benndorf, R., Hayess, K., Priemer, E. and Engel, K.
Journal of Biological Chemistry 267
: 21607-21611.
1 January 1992
Involvement of pertussis toxin-sensitive G-proteins in the hormonal inhibition of dihydropyridine-sensitive Ca2+ currents in an insulin-secreting cell line (RINm5F).
Schmidt, A., Hescheler, J., Offermanns, S., Spicher, K., Hinsch, K.D., Klinz, F.J., Codina, J., Birnbaumer, L., Gausepohl, H., Frank, R., Schultz, G. and Rosenthal, W.
Journal of Biological Chemistry 266
(27): 18025-18033.
25 September 1991
Evidence for opioid receptor-mediated activation of the G-proteins, Go and Gi2, in membranes of neuroblastoma x glioma (NG108-15) hybrid cells.
Offermanns, S., Schultz, G. and Rosenthal, W.
Journal of Biological Chemistry 266
(6): 3365-3368.
25 February 1991
Identification of the phosphorylation sites of the murine small heat shock protein hsp25.
Gaestel, M., Schroeder, W., Benndorf, R., Lippmann, C., Buchner, K., Hucho, F., Erdmann, V.A. and Bielka, H.
Journal of Biological Chemistry 266
: 14721-14724.
1 January 1991
Electron spin resonance investigation of tyrosyl radicals of prostaglandin H synthase.
Lassmann, G., Odenwaller, R., Curtis, J.F., DeGray, J.A., Mason, R.P., Marnett, L.J. and Eling, T.E.
Journal of Biological Chemistry 266
: 20045-20055.
1 January 1991
An active serine is involved in covalent substrate amino acid binding at each reaction center of gramicidin S synthetase.
Schlumbohm, W., Stein, T., Ullrich, C., Vater, J., Krause, M., Marahiel, M.A., Kruft, V. and Wittmann-Liebold, B.
Journal of Biological Chemistry 266
: 23135-23141.
1 January 1991
The regulation of intracellular pH in monkey kidney epithelial cells (BSC-1). Roles of Na+/H+ antiport, Na+-HCO3(-)-(NaCO3-) symport, and Cl-/HCO3- exchange.
Jentsch, T.J., Janicke, I., Sorgenfrei, D., Keller, S.K. and Wiederholt, M.
Journal of Biological Chemistry 261
(26): 12120-12127.
15 September 1986
Kinetic properties of the sodium bicarbonate (carbonate) symport in monkey kidney epithelial cells (BSC-1). Interactions between Na+, HCO-3, and pH.
Jentsch, T.J., Schwartz, P., Schill, B.S., Langner, B., Lepple, A.P., Keller, S.K. and Wiederholt, M.
Journal of Biological Chemistry 261
(23): 10673-10679.
15 August 1986
Kidney epithelial cells of monkey origin (BSC-1) express a sodium bicarbonate cotransport. Characterization by 22Na+ flux measurements.
Jentsch, T.J., Schill, B.S., Schwartz, P., Matthes, H., Keller, S.K. and Wiederholt, M.
Journal of Biological Chemistry 260
(29): 15554-15560.
15 December 1985
Characterization by two-dimensional peptide mapping of the gamma subunits of Ns and Ni, the regulatory proteins of adenylyl cyclase, and of transducin, the guanine nucleotide-binding protein of rod outer segments of the eye.
Hildebrandt, J.D., Codina, J., Rosenthal, W., Birnbaumer, L., Neer, E.J., Yamazaki, A. and Bitensky, M.W.
Journal of Biological Chemistry 260
(27): 14867-14872.
25 November 1985
A bicarbonate-dependent process inhibitable by disulfonic stilbenes and a Na+/H+ exchange mediate 22Na+ uptake into cultured bovine corneal endothelium.
Jentsch, T.J., Stahlknecht, T.R., Hollwede, H., Fischer, D.G., Keller, S.K. and Wiederholt, M.
Journal of Biological Chemistry 260
(2): 795-801.
25 January 1985
Review
Dynamin-like MxA GTPase: Structural insights into oligomerization and implications for antiviral activity.
Haller, O., Gao, S., von der Malsburg, A., Daumke, O. and Kochs, G.
Journal of Biological Chemistry 285
(37): 28419-28424.
10 September 2010
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