APL Bioengineering

Remodeling of an in vitro microvessel exposed to cyclic mechanical stretch.
Zeinali, S. ORCID: https://orcid.org/0000-0003-3896-596X, Thompson, E.K., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Geiser, T. and Guenat, O.T. ORCID: https://orcid.org/0000-0003-1103-9712
APL Bioengineering 5 (2): 026102. June 2021

APMIS

Legionella species of different human prevalence induce different rates of apoptosis in human monocytic cells.
Walz, J.M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Faigle, M., Wolburg, H. and Neumeister, B.
APMIS 108 (6): 398-408. January 2000

Advanced Science

Single-cell RNA sequencing delineates renal anti-fibrotic mechanisms mediated by TRPC6 inhibition.
Xu, Yao ORCID: https://orcid.org/0000-0002-3840-9077, Zheng, Zhihuang ORCID: https://orcid.org/0000-0002-5114-3824, Oswald, Marleen Silke, Cheng, Guozhe, Liu, Jun, Zhai, Qidi, Kruegel, Ute, Schaefer, Michael, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384, Endlich, Nicole, Gollasch, Maik ORCID: https://orcid.org/0000-0003-2797-1934, Simm, Stefan and Tsvetkov, Dmitry ORCID: https://orcid.org/0000-0002-6472-971X
Advanced Science 12 (33): e01175. 4 September 2025

External mechanical stability regulates hematoma vascularization in bone healing rather than endothelial YAP/TAZ mechanotransduction.
Mehl, J. ORCID: https://orcid.org/0000-0002-8279-7142, Farahani, S.K., Brauer, E., Klaus-Bergmann, A. ORCID: https://orcid.org/0000-0002-1164-3322, Thiele, T., Ellinghaus, A., Bartels-Klein, E., Koch, K., Schmidt-Bleek, K., Petersen, A., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Vogel, V. and Duda, G.N. ORCID: https://orcid.org/0000-0001-7605-3908
Advanced Science 11 (13): e2307050. 3 April 2024

American Journal of Pathology

A new method for large scale isolation of kidney glomeruli from mice.
Takemoto, M., Asker, N., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Lundkvist, A., Johansson, B.R., Saito, Y. and Betsholtz, C.
American Journal of Pathology 161 (3): 799-805. September 2002

Anatomical Record

The peripapillary glia of the optic nerve head in the chicken retina.
Schuck, J., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Wolburg, H.
Anatomical Record 259 (3): 263-275. 1 July 2000

Angiogenesis

Unique vascular phenotypes following over-expression of individual VEGFA isoforms from the developing lens.
Mitchell, C.A., Rutland, C.S., Walker, M., Nasir, M., Foss, A.J.E., Stewart, C., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Konerding, M.A., Risau, W. and Drexler, H.C.A.
Angiogenesis 9 (4): 209-224. December 2006

Arteriosclerosis Thrombosis and Vascular Biology

Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish.
Geudens, I., Herpers, R., Hermans, K., Segura, I., Ruiz de Almodovar, C., Bussmann, J., De Smet, F., Vandevelde, W., Hogan, B.M., Siekmann, A., Claes, F., Moore, J.C., Pistocchi, A.S., Loges, S., Mazzone, M., Mariggi, G., Bruyère, F., Cotelli, F., Kerjaschki, D., Noël, A., Foidart, J.M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Ny, A., Langenberg, T., Lawson, N.D., Duckers, H.J., Schulte-Merker, S., Carmeliet, P. and Dewerchin, M.
Arteriosclerosis Thrombosis and Vascular Biology 30 (9): 1695-1702. September 2010

BMJ Open

Protocol of the Berlin Long-term Observation of Vascular Events (BeLOVE): a prospective cohort study with deep phenotyping and long-term follow up of cardiovascular high-risk patients.
Weber, J.E. ORCID: https://orcid.org/0000-0002-1666-6021, Ahmadi, M. ORCID: https://orcid.org/0000-0001-5792-4704, Boldt, L.H. ORCID: https://orcid.org/0000-0002-3320-0880, Eckardt, K.U. ORCID: https://orcid.org/0000-0003-3823-0920, Edelmann, F. ORCID: https://orcid.org/0000-0003-4401-5936, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Grittner, U. ORCID: https://orcid.org/0000-0003-2595-0224, Haubold, K. ORCID: https://orcid.org/0000-0001-5108-5356, Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Kollmus-Heege, J. ORCID: https://orcid.org/0000-0003-3183-4932, Landmesser, U. ORCID: https://orcid.org/0000-0002-0214-3203, Leistner, D.M. ORCID: https://orcid.org/0000-0002-4351-420X, Mai, K. ORCID: https://orcid.org/0000-0003-0126-3155, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Nolte, C.H. ORCID: https://orcid.org/0000-0001-5577-1775, Pieske, B. ORCID: https://orcid.org/0000-0002-6466-5306, Piper, S.K. ORCID: https://orcid.org/0000-0002-0147-8992, Rattan, S. ORCID: https://orcid.org/0009-0006-3684-0660, Rauch, G. ORCID: https://orcid.org/0000-0002-2451-1660, Schmidt, S. ORCID: https://orcid.org/0000-0002-6698-5717, Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142, Schönrath, K. ORCID: https://orcid.org/0000-0002-7973-7536, Schulz-Menger, J. ORCID: https://orcid.org/0000-0003-3100-1092, Schweizerhof, O. ORCID: https://orcid.org/0000-0002-8954-4818, Siegerink, B. ORCID: https://orcid.org/0000-0002-8454-9142, Spranger, J. ORCID: https://orcid.org/0000-0002-8900-4467, Ramachandran, V.S. ORCID: https://orcid.org/0000-0001-7357-5970, Witzenrath, M. ORCID: https://orcid.org/0000-0002-9787-5633, Endres, M. ORCID: https://orcid.org/0000-0001-6520-3720 and Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X
BMJ Open 13 (10): e076415. 31 October 2023

Biochemical Society Transactions

VEGFRs and Notch: a dynamic collaboration in vascular patterning.
Jakobsson, L. ORCID: https://orcid.org/0000-0001-7956-587X, Bentley, K. ORCID: https://orcid.org/0000-0002-9391-659X and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Biochemical Society Transactions 37 (Pt 6): 1233-1236. December 2009

Heparan sulphate requirement in platelet-derived growth factor B-mediated pericyte recruitment.
Kurup, S., Abramsson, A., Li, J.P., Lindahl, U., Kjellen, L., Betsholtz, C., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Spillmann, D.
Biochemical Society Transactions 34 (3): 454-455. 1 June 2006

Biochemical and Biophysical Research Communications

NanoSIMS imaging reveals unexpected heterogeneity in nutrient uptake by brown adipocytes.
He, C., Hu, X., Weston, T.A., Jung, R.S., Heizer, P., Tu, Y., Ellison, R., Matsumoto, K., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Tontonoz, P., Fong, L.G., Young, S.G. and Jiang, H.
Biochemical and Biophysical Research Communications 504 (4): 899-902. 12 October 2018

Biological Chemistry

Influence of phosphorylation on intermediate filaments.
Kraxner, J. ORCID: https://orcid.org/0000-0002-3515-7468 and Köster, S. ORCID: https://orcid.org/0000-0002-0009-1024
Biological Chemistry 404 (8-9): 821-827. 20 April 2023

Biology Open

Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification.
Petzold, Tim ORCID: https://orcid.org/0000-0001-9788-6167, Brivio, Sarah ORCID: https://orcid.org/0000-0003-1913-8686, Linnerz, Tanja ORCID: https://orcid.org/0000-0001-8127-780X, Watanabe, Masakatsu ORCID: https://orcid.org/0000-0002-5744-197X, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384 and Bertrand, Julien Y.
Biology Open 14 (8): bio062118. August 2025

First person - Tim Petzold.
Petzold, Tim ORCID: https://orcid.org/0000-0001-9788-6167
Biology Open 14 (8): bio062142. August 2025

Biophysical Journal

PolNet: a tool to quantify network-level cell polarity and blood flow in vascular remodeling.
Bernabeu, M.O., Jones, M.L., Nash, R.W., Pezzarossa, A., Coveney, P.V., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Franco, C.A.
Biophysical Journal 114 (9): 2052-2058. 8 May 2018

Blood

Peripheral mural cell recruitment requires cell-autonomous heparan sulfate.
Stenzel, D., Nye, E., Nisancioglu, M., Adams, R.H., Yamaguchi, Y. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Blood 114 (4): 915-924. 23 July 2009

Bone

How vascularization is reciprocally coupled to chondrogenesis and osteogenesis in bone healing: lessons from the growth plate.
Mehl, Julia, Schmidt-Bleek, Katharina, Ellinghaus, Agnes, Mundlos, Stefan, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384, Duda, Georg N. and Vogel, Viola
Bone 200 : 117595. November 2025

Brain Research Developmental Brain Research

Maturation of the blood-retina barrier in the developing pecten oculi of the chicken.
Liebner, S., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Wolburg, H.
Brain Research Developmental Brain Research 100 (2): 205-219. 18 June 1997

Cancer Cell

Tumor vessel normalization by chloroquine independent of autophagy.
Maes, H., Kuchnio, A., Peric, A., Moens, S., Nys, K., De Bock, K., Quaegebeur, A., Schoors, S., Georgiadou, M., Wouters, J., Vinckier, S., Vankelecom, H., Garmyn, M., Vion, A.C., Radtke, F., Boulanger, C., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Dejana, E., Dewerchin, M., Ghesquière, B., Annaert, W., Agostinis, P. and Carmeliet, P.
Cancer Cell 26 (2): 190-206. 11 August 2014

Cancer Research

Lymphoma angiogenesis is orchestrated by noncanonical signaling pathways.
Gloger, M. ORCID: https://orcid.org/0000-0002-3319-7642, Menzel, L. ORCID: https://orcid.org/0000-0002-3816-6255, Grau, M., Vion, A.C. ORCID: https://orcid.org/0000-0002-2788-2512, Anagnostopoulos, I., Zapukhlyak, M., Gerlach, K., Kammertöns, T. ORCID: https://orcid.org/0000-0003-3309-5141, Hehlgans, T., Zschummel, M. ORCID: https://orcid.org/0000-0002-4778-8742, Lenz, G., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950
Cancer Research 80 (6): 1316-1329. March 2020

Cell

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K. ORCID: https://orcid.org/0000-0002-8244-6887, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Cheng, J.Y. ORCID: https://orcid.org/0000-0001-8942-0607, Russo, G., Hernandez-Miranda, L.R. ORCID: https://orcid.org/0000-0002-0498-708X, Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Zauber, H. ORCID: https://orcid.org/0000-0003-2595-1147, Rudolph, I.M. ORCID: https://orcid.org/0000-0002-3903-0755, Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Haucke, V. ORCID: https://orcid.org/0000-0003-3119-6993, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Krauss, M., Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Pascual, J.M. and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Cell 175 (1): 239-253. 20 September 2018

Role of PFKFB3-driven glycolysis in vessel sprouting.
De Bock, K., Georgiadou, M., Schoors, S., Kuchnio, A., Wong, B.W., Cantelmo, A.R., Quaegebeur, A., Ghesquière, B., Cauwenberghs, S., Eelen, G., Phng, L.K., Betz, I., Tembuyser, B., Brepoels, K., Welti, J., Geudens, I., Segura, I., Cruys, B., Bifari, F., Decimo, I., Blanco, R., Wyns, S., Vangindertael, J., Rocha, S., Collins, R.T. ORCID: https://orcid.org/0000-0002-1847-4517, Munck, S., Daelemans, D., Imamura, H., Devlieger, R., Rider, M., Van Veldhoven, P.P., Schuit, F., Bartrons, R., Hofkens, J., Fraisl, P., Telang, S., DeBerardinis, R.J., Schoonjans, L., Vinckier, S., Chesney, J., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Dewerchin, M. and Carmeliet, P.
Cell 154 (3): 651-663. 1 August 2013

Basic and therapeutic aspects of angiogenesis.
Potente, M. ORCID: https://orcid.org/0000-0002-5689-0036, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Carmeliet, P.
Cell 146 (6): 873-887. 16 September 2011

Cell Adhesion & Migration

VEGF and Notch signaling: the yin and yang of angiogenic sprouting.
Hellström, M. ORCID: https://orcid.org/0000-0002-7088-9533, Phng, L.K. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Cell Adhesion & Migration 1 (3): 133-136. July 2007

Cell Death and Differentiation

Protein kinase A regulates ferroptosis by controlling GPX4 m(6)A modification through phosphorylation of ALKBH5.
Zhao, X. ORCID: https://orcid.org/0000-0002-4048-6813, Sun, Y. ORCID: https://orcid.org/0009-0005-8556-356X, Zou, J., Wu, Y., Huang, M., Kong, H., Liu, G., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Gu, W. ORCID: https://orcid.org/0000-0002-1480-2368, Zhang, Y. ORCID: https://orcid.org/0000-0002-6465-7488, Shang, M. ORCID: https://orcid.org/0000-0003-4511-4290 and Wang, X. ORCID: https://orcid.org/0000-0002-2457-8726
Cell Death and Differentiation 32 (6): 1617. June 2025

Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems.
Cesca, F., Yabe, A., Spencer-Dene, B., Scholz-Starke, J., Medrihan, L., Maden, C.H., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Orriss, I.R., Baldelli, P., Al-Qatari, M., Koltzenburg, M., Adams, R.H., Benfenati, F. and Schiavo, G.
Cell Death and Differentiation 19 (2): 194-208. February 2012

Cell Metabolism

Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.
Schoors, S., De Bock, K., Cantelmo, A.R., Georgiadou, M., Ghesquière, B., Cauwenberghs, S., Kuchnio, A., Wong, B.W., Quaegebeur, A., Goveia, J., Bifari, F., Wang, X., Blanco, R., Tembuyser, B., Cornelissen, I., Bouché, A., Vinckier, S., Diaz-Moralli, S., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Telang, S., Cascante, M., Chesney, J., Dewerchin, M. and Carmeliet, P.
Cell Metabolism 19 (1): 37-48. 7 January 2014

Cell Reports

Endothelial calcineurin signaling restrains metastatic outgrowth by regulating Bmp2.
Hendrikx, S., Coso, S., Prat-Luri, B., Wetterwald, L., Sabine, A., Franco, C.A., Nassiri, S., Zangger, N., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Delorenzi, M. and Petrova, T.V.
Cell Reports 26 (5): 1227-1241. 29 January 2019

Knockout of the PKN family of Rho effector kinases reveals a non-redundant role for PKN2 in developmental mesoderm expansion.
Quétier, I., Marshall, J.J.T., Spencer-Dene, B., Lachmann, S., Casamassima, A., Franco, C., Escuin, S., Worrall, J.T., Baskaran, P., Rajeeve, V., Howell, M., Copp, A.J., Stamp, G., Rosewell, I., Cutillas, P., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Parker, P.J. and Cameron, A.J.M.
Cell Reports 14 (3): 440-448. 26 January 2016

Cell Stem Cell

Mouse cutaneous melanoma induced by mutant BRaf arises from expansion and dedifferentiation of mature pigmented melanocytes.
Köhler, C., Nittner, D., Rambow, F., Radaelli, E., Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Vandamme, N., Baggiolini, A., Sommer, L., Berx, G., van den Oord, J.J., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Blanpain, C. and Marine, J.C.
Cell Stem Cell 21 (5): 679-693.e6. 2 November 2017

Pericytes or mesenchymal stem cells: is that the question?
Cano, E. ORCID: https://orcid.org/0000-0003-1091-8934, Gebala, V. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Cell Stem Cell 20 (3): 296-297. 2 March 2017

Cell and Tissue Research

Endothelial-pericyte interactions in angiogenesis.
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Betsholtz, C.
Cell and Tissue Research 314 (1): 15-23. October 2003

Ultrastructural localization of adhesion molecules in the healthy and inflamed choroid plexus of the mouse.
Wolburg, K., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Schulz, M., Wolburg, H. and Engelhardt, B.
Cell and Tissue Research 296 (2): 259-269. April 1999

The pecten oculi of the chicken as a new in vivo model of the blood-brain barrier.
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Liebner, S. and Wolburg, H.
Cell and Tissue Research 285 (1): 91-100. June 1996

Cells

Caspase-6 is a non-apoptotic effector of shear-induced morphological adaptation in pulmonary artery endothelial cells in vitro.
Wittig, Corey ORCID: https://orcid.org/0000-0003-4296-9293, Akmeriç, Emir Bora ORCID: https://orcid.org/0000-0003-4463-8017, Michalick, Laura ORCID: https://orcid.org/0000-0002-3959-5828, König, Jakob M., Kuebler, Wolfgang M. ORCID: https://orcid.org/0000-0003-4100-2961, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384 and Szulcek, Robert ORCID: https://orcid.org/0000-0003-0450-7338
Cells 14 (21): 1669. 25 October 2025

Opposite macrophage polarization in different subsets of ovarian cancer: observation from a pilot study.
Vankerckhoven, A., Wouters, R., Mathivet, T., Ceusters, J., Baert, T., Van Hoylandt, A., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Vergote, I. and Coosemans, A.
Cells 9 (2): 305. 27 January 2020

Circulation Research

Metabolic and immune crosstalk in cardiovascular disease.
Mohanta, S.K. ORCID: https://orcid.org/0000-0001-6144-4092, Heron, C. ORCID: https://orcid.org/0000-0002-3376-0685, Klaus-Bergmann, A. ORCID: https://orcid.org/0000-0002-1164-3322, Horstmann, H. ORCID: https://orcid.org/0000-0002-9971-1800, Brakenhielm, E. ORCID: https://orcid.org/0000-0003-3378-8300, Giannarelli, C. ORCID: https://orcid.org/0000-0003-2473-6058, Habenicht, A.J.R. ORCID: https://orcid.org/0000-0003-2901-3027, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Weber, C. ORCID: https://orcid.org/0000-0003-4610-8714
Circulation Research 136 (11): 1433-1453. 23 May 2025

Intramyocardial sprouting tip cells specify coronary arterialization.
Cano, E. ORCID: https://orcid.org/0000-0003-1091-8934, Schwarzkopf, J. ORCID: https://orcid.org/0000-0001-9552-0794, Kanda, M. ORCID: https://orcid.org/0000-0003-3468-3586, Lindberg, E.L. ORCID: https://orcid.org/0000-0002-2979-433X, Hollfinger, I. ORCID: https://orcid.org/0000-0002-6233-8395, Pogontke, C. ORCID: https://orcid.org/0000-0002-9610-9822, Braeuning, C. ORCID: https://orcid.org/0009-0007-1439-9920, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Circulation Research 135 (6): 671-684. 30 August 2024

ATTRACT: arterial flow as attractor for endothelial cell migration.
Georgieva, P.B. ORCID: https://orcid.org/0000-0002-6347-2297, Marchuk, D.A. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Circulation Research 125 (3): 262-264. July 2019

Endothelial alpha-parvin controls integrity of developing vasculature and is required for maintenance of cell-cell junctions.
Fraccaroli, A., Pitter, B., Taha, A.A., Seebach, J., Huveneers, S., Kirsch, J., Casaroli-Marano, R.P., Zahler, S., Pohl, U., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Schnittler, H.J. and Montanez, E.
Circulation Research 117 (1): 29-40. 19 June 2015

Laminin-binding integrins induce Dll4 expression and Notch signaling in endothelial cells.
Estrach, S., Cailleteau, L., Franco, C.A. ORCID: https://orcid.org/0000-0002-2861-3883, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Stefani, C. ORCID: https://orcid.org/0000-0003-3420-432X, Lemichez, E. ORCID: https://orcid.org/0000-0001-9080-7761, Gagnoux-Palacios, L., Meneguzzi, G. ORCID: https://orcid.org/0000-0002-1609-6540 and Mettouchi, A.
Circulation Research 109 (2): 172-182. 8 July 2011

Cold Spring Harbor Perspectives in Biology

Hold me, but not too tight - endothelial cell-cell junctions in angiogenesis.
Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Cold Spring Harbor Perspectives in Biology 10 (8): a029223. August 2018

Cold Spring Harbor Perspectives in Medicine

VEGF and Notch in tip and stalk cell selection.
Blanco, R. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Cold Spring Harbor Perspectives in Medicine 3 (1): a006569. 1 January 2013

Communicative & Integrative Biology

Tissue guidance without filopodia.
Wacker, A., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Phng, L.K.
Communicative & Integrative Biology 7 (1): e28820. 9 April 2014

Current Opinion in Cell Biology

Endothelial development taking shape.
Wacker, A. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Current Opinion in Cell Biology 23 (6): 676-685. December 2011

Current Opinion in Genetics & Development

Vascular morphogenesis: a Wnt for every vessel?
Franco, C.A., Liebner, S. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Current Opinion in Genetics & Development 19 (5): 476-483. October 2009

Current Opinion in Nephrology and Hypertension

Role of platelet-derived growth factor in mesangium development and vasculopathies: lessons from platelet-derived growth factor and platelet-derived growth factor receptor mutations in mice.
Betsholtz, C., Lindblom, P., Bjarnegard, M., Enge, M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Lindahl, P.
Current Opinion in Nephrology and Hypertension 13 (1): 45-52. January 2004

Development

BMAL1 modulates glutamine supply to control haematopoietic stem and progenitor cell expansion.
Petzold, Tim ORCID: https://orcid.org/0000-0001-9788-6167, Lutes, Lydia K. ORCID: https://orcid.org/0000-0001-6133-6294, Batista, Keila Navarro I., Konle, Antonia, Baechler, Bastien, Jemelin, Stéphane, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384, Golub, Rachel ORCID: https://orcid.org/0000-0002-2306-5363, Scheiermann, Christoph and Bertrand, Julien Y. ORCID: https://orcid.org/0000-0001-6570-4082
Development 153 (8): dev204726. April 2026

In preprints: keeping endothelial cell specification and vascular development in check.
Petzold, T. ORCID: https://orcid.org/0000-0001-9788-6167 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Development 151 (18): dev204338. September 2024

Svep1 stabilises developmental vascular anastomosis in reduced flow conditions.
Coxam, B. ORCID: https://orcid.org/0000-0003-1606-6373, Collins, R.T. ORCID: https://orcid.org/0000-0002-1847-4517, Hußmann, M., Huisman, Y. ORCID: https://orcid.org/0000-0001-5076-826X, Meier, K., Jung, S., Bartels-Klein, E., Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Finotto, L. ORCID: https://orcid.org/0000-0002-4695-9343, Helker, C.S.M., Stainier, D.Y.R. ORCID: https://orcid.org/0000-0002-0382-0026, Schulte-Merker, S. ORCID: https://orcid.org/0000-0003-3617-8807 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Development 149 (6): dev199858. 24 March 2022

WASp controls oriented migration of endothelial cells to achieve functional vascular patterning.
Rosa, A. ORCID: https://orcid.org/0000-0003-4505-9260, Giese, W. ORCID: https://orcid.org/0000-0003-0872-0929, Meier, K., Alt, S. ORCID: https://orcid.org/0000-0003-1877-2968, Klaus-Bergmann, A. ORCID: https://orcid.org/0000-0002-1164-3322, Edgar, L.T. ORCID: https://orcid.org/0000-0002-8586-1605, Bartels, E., Collins, R. ORCID: https://orcid.org/0000-0002-1847-4517, Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Coxam, B. ORCID: https://orcid.org/0000-0003-1606-6373, Bernabeu, M.O. ORCID: https://orcid.org/0000-0002-6456-3756 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Development 149 (3): dev200195. February 2022

Vasohibin-1 selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk.
Bastos de Oliveira, M. ORCID: https://orcid.org/0000-0002-6635-3963, Meier, K., Jung, S., Bartels-Klein, E., Coxam, B. ORCID: https://orcid.org/0000-0003-1606-6373, Geudens, I., Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Skoczylas, R., Fechner, I. ORCID: https://orcid.org/0000-0002-0184-8324, Koltowska, K. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Development 148 (4): dev194993. 19 February 2021

Artery-vein specification in the zebrafish trunk is pre-patterned by heterogeneous Notch activity and balanced by flow-mediated fine tuning.
Geudens, I., Coxam, B. ORCID: https://orcid.org/0000-0003-1606-6373, Alt, S. ORCID: https://orcid.org/0000-0003-1877-2968, Gebala, V., Vion, A.C. ORCID: https://orcid.org/0000-0002-2788-2512, Meier, K., Rosa, A. ORCID: https://orcid.org/0000-0003-4505-9260 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Development 146 (16): dev.181024. 27 August 2019

cAMP-dependent protein kinase A (PKA) regulates angiogenesis by modulating tip cell behavior in a Notch-independent manner.
Nedvetsky, P.I., Zhao, X., Mathivet, T., Aspalter, I.M., Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Metzger, R.J., Mostov, K.E. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Development 143 (19): 3582-3590. 4 October 2016

Integrin signalling regulates YAP and TAZ to control skin homeostasis.
Elbediwy, A., Vincent-Mistiaen, Z.I., Spencer-Dene, B., Stone, R.K., Boeing, S., Wculek, S.K., Cordero, J., Tan, E.H., Ridgway, R., Brunton, V.G., Sahai, E., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Behrens, A., Malanchi, I., Sansom, O.J. and Thompson, B.J.
Development 143 (10): 1674-1687. 15 May 2016

Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
Fan, J., Ponferrada, V.G., Sato, T., Vemaraju, S., Fruttiger, M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Ferrara, N. and Lang, R. A.
Development 141 (2): 448-459. January 2014

Filopodia are dispensable for endothelial tip cell guidance.
Phng, L.K., Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Development 140 (19): 4031-4040. October 2013

SRF selectively controls tip cell invasive behavior in angiogenesis.
Franco, C.A. ORCID: https://orcid.org/0000-0002-2861-3883, Blanc, J., Parlakian, A. ORCID: https://orcid.org/0000-0002-0928-2185, Blanco, R., Aspalter, I.M., Kazakova, N., Diguet, N. ORCID: https://orcid.org/0000-0001-9963-7623, Mylonas, E., Gao-Li, J., Vaahtokari, A., Penard-Lacronique, V. ORCID: https://orcid.org/0000-0001-9435-7331, Fruttiger, M., Rosewell, I., Mericskay, M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Li, Z. ORCID: https://orcid.org/0000-0002-3706-4505
Development 140 (11): 2321-2333. June 2013

A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development.
Villefranc, J.A., Nicoli, S., Bentley, K., Jeltsch, M., Zarkada, G., Moore, J.C., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Alitalo, K. and Lawson, N.D.
Development 140 (7): 1497-1506. April 2013

Coordinating cell behaviour during blood vessel formation.
Geudens, I. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Development 138 (21): 4569-4583. November 2011

Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis.
Stenzel, D., Lundkvist, A., Sauvaget, D., Busse, M., Graupera, M., van der Flier, A., Wijelath, E.S., Murray, J., Sobel, M., Costell, M., Takahashi, S., Fässler, R., Yamaguchi, Y., Gutmann, D.H. ORCID: https://orcid.org/0000-0002-3127-5045, Hynes, R.O. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Development 138 (20): 4451-4463. 15 October 2011

Developmental Biology

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling.
Haigh, J.J., Morelli, P.I., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Haigh, K., Tsien, J., Damert, A., Miquerol, L., Muhlner, U., Klein, R., Ferrara, N., Wagner, E.F., Betsholtz, C. and Nagy, A.
Developmental Biology 262 (2): 225-241. 15 October 2003

Developmental Cell

Apical and basal matrix remodeling control epithelial morphogenesis.
Diaz-de-la-Loza, M.D.C., Ray, R.P., Ganguly, P.S., Alt, S. ORCID: https://orcid.org/0000-0003-1877-2968, Davis, J.R., Hoppe, A., Tapon, N., Salbreux, G. and Thompson, B.J.
Developmental Cell 46 (1): 23-39. 2 July 2018

Morph or move? How distinct endothelial cell responses to blood flow shape vascular networks.
Franco, C.A. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Developmental Cell 41 (6): 574-576. 19 June 2017

Formin-mediated actin polymerization at endothelial junctions is required for vessel lumen formation and stabilization.
Phng, L.K., Gebala, V., Bentley, K., Philippides, A., Wacker, A., Mathivet, T., Sauteur, L., Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Belting, H.G., Affolter, M. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Developmental Cell 32 (1): 123-132. 12 January 2015

The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling.
Birdsey, G.M., Shah, A.V., Dufton, N., Reynolds, L.E., Osuna Almagro, L., Yang, Y., Aspalter, I.M., Khan, S.T., Mason, J.C., Dejana, E., Göttgens, B., Hodivala-Dilke, K., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Adams, R.H. and Randi, A.M.
Developmental Cell 32 (1): 82-96. 12 January 2015

Angiogenesis: a team effort coordinated by notch.
Phng, L.K. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Developmental Cell 16 (2): 196-208. 17 February 2009

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis.
Phng, L.K., Potente, M. ORCID: https://orcid.org/0000-0002-5689-0036, Leslie, J.D., Babbage, J., Nyqvist, D., Lobov, I., Ondr, J.K., Rao, S., Lang, R.A., Thurston, G. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Developmental Cell 16 (1): 70-82. 20 January 2009

Developmental Dynamics

Coelomic epithelium-derived cells in visceral morphogenesis.
Ariza, L., Carmona, R. ORCID: https://orcid.org/0000-0002-9686-473X, Canete, A. ORCID: https://orcid.org/0000-0003-4752-8251, Cano, E. ORCID: https://orcid.org/0000-0003-1091-8934 and Munoz-Chapuli, R. ORCID: https://orcid.org/0000-0001-6392-6802
Developmental Dynamics 245 (3): 307-322. March 2016

Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate.
Wright, D., Ferjentsik, Z., Chong, S.W., Qiu, X., Yun-Jin, J. ORCID: https://orcid.org/0000-0003-0499-7306, Malapert, P., Pourquié, O. ORCID: https://orcid.org/0000-0001-5189-1227, Van Hateren, N., Wilson, S.A. ORCID: https://orcid.org/0000-0003-3073-258X, Franco, C., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Dale, J.K. ORCID: https://orcid.org/0000-0002-9294-947X and Maroto, M.
Developmental Dynamics 238 (12): 3043-3055. December 2009

Neuropilin-1 is required for endothelial tip cell guidance in the developing central nervous system.
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Ruhrberg, C., Abramsson, A., Fujisawa, H., Shima, D. and Betsholtz, C.
Developmental Dynamics 231 (3): 503-509. November 2004

N-cadherin mediates pericytic-endothelial interaction during brain angiogenesis in the chicken.
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Wolburg, H. and Redies, C.
Developmental Dynamics 218 (3): 472-479. July 2000

Differential expression of endothelial β-catenin and plakoglobin during development and maturation of the blood-brain and blood-retina barrier in the chicken.
Liebner, S., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Wolburg, H.
Developmental Dynamics 217 (1): 86-98. January 2000

EMBO Journal

PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7.
Martin, M., Geudens, I., Bruyr, J., Potente, M. ORCID: https://orcid.org/0000-0002-5689-0036, Bleuart, A., Lebrun, M., Simonis, N., Deroanne, C., Twizere, J.C., Soubeyran, P., Peixoto, P., Mottet, D., Janssens, V., Hofmann, W.K., Claes, F., Carmeliet, P., Kettmann, R., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Dequiedt, F.
EMBO Journal 32 (18): 2491-2503. 11 September 2013

Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy.
Enge, M., Bjarnegård, M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Gustafsson, E., Kalén, M., Asker, N., Hammes, H.-P., Shani, M., Fässler, R. and Betsholtz, C.
EMBO Journal 21 (16): 4307-4316. 15 August 2002

EMBO Molecular Medicine

Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma.
Finotto, L. ORCID: https://orcid.org/0000-0002-4695-9343, Cole, B. ORCID: https://orcid.org/0000-0001-5899-5598, Giese, W. ORCID: https://orcid.org/0000-0003-0872-0929, Baumann, E. ORCID: https://orcid.org/0000-0002-7804-4885, Claeys, A., Vanmechelen, M. ORCID: https://orcid.org/0000-0002-8342-3150, Decraene, B. ORCID: https://orcid.org/0000-0002-2523-452X, Derweduwe, M. ORCID: https://orcid.org/0000-0002-4960-4847, Dubroja Lakic, N., Shankar, G., Nagathihalli Kantharaju, M., Albrecht, J.P. ORCID: https://orcid.org/0000-0002-3792-9695, Geudens, I. ORCID: https://orcid.org/0000-0003-3297-4208, Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Ligon, K.L. ORCID: https://orcid.org/0000-0002-7733-600X, Boeckx, B. ORCID: https://orcid.org/0000-0002-0296-6680, Lambrechts, D. ORCID: https://orcid.org/0000-0002-3429-302X, Harrington, K. ORCID: https://orcid.org/0000-0002-7237-1973, Van Den Bosch, L. ORCID: https://orcid.org/0000-0003-0104-4067, De Vleeschouwer, S. ORCID: https://orcid.org/0000-0002-9576-9917, De Smet, F. ORCID: https://orcid.org/0000-0002-6669-3335 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
EMBO Molecular Medicine 15 (11): e18144. 8 November 2023

Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth.
Mathivet, T. ORCID: https://orcid.org/0000-0001-7761-1684, Bouleti, C., Van Woensel, M., Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Verschuere, T., Phng, L.K., Dejaegher, J., Balcer, M., Matsumoto, K., Georgieva, P.B. ORCID: https://orcid.org/0000-0002-6347-2297, Belmans, J., Sciot, R., Stockmann, C., Mazzone, M. ORCID: https://orcid.org/0000-0001-8824-4015, De Vleeschouwer, S. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
EMBO Molecular Medicine 9 (12): 1629-1645. 1 December 2017

EMBO Reports

PAR-3 controls endothelial planar polarity and vascular inflammation under laminar flow.
Hikita, T., Mirzapourshafiyi, F., Barbacena, P., Riddell, M., Pasha, A., Li, M., Kawamura, T., Brandes, R.P., Hirose, T., Ohno, S., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Matsuda, M., Franco, C.A. ORCID: https://orcid.org/0000-0002-2861-3883 and Nakayama, M. ORCID: https://orcid.org/0000-0002-0153-7198
EMBO Reports 19 (9): e45253. 1 September 2018

Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo.
Stenzel, D., Franco, C.A. ORCID: https://orcid.org/0000-0002-2861-3883, Estrach, S., Mettouchi, A., Sauvaget, D., Rosewell, I., Schertel, A., Armer, H., Domogatskaya, A. ORCID: https://orcid.org/0000-0002-6468-1963, Rodin, S. ORCID: https://orcid.org/0000-0002-6954-1986, Tryggvason, K., Collinson, L., Sorokin, L. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
EMBO Reports 12 (11): 1135-1143. 1 November 2011

Endocrinology

Pericyte insulin receptors modulate retinal vascular remodeling and endothelial angiopoietin signaling.
Warmke, N., Platt, F., Bruns, A.F., Ozber, C.H., Haywood, N.J., Abudushalamu, Y., Slater, C., Palin, V., Sukumar, P., Wheatcroft, S.B. ORCID: https://orcid.org/0000-0002-6741-9012, Yuldasheva, N.Y., Kearney, M.T., Griffin, K.J. ORCID: https://orcid.org/0000-0002-3154-3273 and Cubbon, R.M. ORCID: https://orcid.org/0000-0001-7844-3600
Endocrinology 162 (11): bqab182. 1 November 2021

European Journal of Heart Failure

Deep phenotyping of heart failure with preserved ejection fraction through multi-omics integration.
Versnjak, Jakob ORCID: https://orcid.org/0009-0009-6179-1014, Kuehne, Titus ORCID: https://orcid.org/0000-0003-1631-4824, Fahjen, Pauline ORCID: https://orcid.org/0000-0002-5015-0643, Jovanovic, Nina ORCID: https://orcid.org/0000-0001-6300-9705, Löber, Ulrike ORCID: https://orcid.org/0000-0001-7468-9531, Schiattarella, Gabriele G. ORCID: https://orcid.org/0000-0002-7582-7171, Wilck, Nicola ORCID: https://orcid.org/0000-0003-3189-5364, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384, Müller, Dominik N. ORCID: https://orcid.org/0000-0003-3650-5644, Edelmann, Frank ORCID: https://orcid.org/0000-0003-4401-5936, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Eils, Roland ORCID: https://orcid.org/0000-0002-0034-4036, Gotthardt, Michael ORCID: https://orcid.org/0000-0003-1788-3172, Forslund, Sofia K. ORCID: https://orcid.org/0000-0003-4285-6993, Wild, Benjamin ORCID: https://orcid.org/0000-0002-7492-8448 and Kelm, Marcus ORCID: https://orcid.org/0000-0003-4971-0452
European Journal of Heart Failure 27 (12): 3243-3259. December 2025

European Journal of Immunology

Dendritic cell expression of the Notch ligand jagged2 is not essential for Th2 response induction in vivo.
Worsley, A.G.F., LeibundGut-Landmann, S. ORCID: https://orcid.org/0000-0002-5724-4837, Slack, E. ORCID: https://orcid.org/0000-0002-2473-1145, Phng, L.K., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Reis e Sousa, C. ORCID: https://orcid.org/0000-0001-7392-2119 and MacDonald, A.S.
European Journal of Immunology 38 (4): 1043-1049. April 2008

European Journal of Neuroscience

N-cadherin expression in endothelial cells during early angiogenesis in the eye and brain of the chicken: relation to blood-retina and blood-brain barrier development.
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Liebner, S., Redies, C. and Wolburg, H.
European Journal of Neuroscience 11 (4): 1191-1201. April 1999

Experientia Supplementum

How do endothelial cells orientate?
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Betsholtz, C.
Experientia Supplementum 94 : 3-15. 2005

Role of pericytes in vascular morphogenesis.
Betsholtz, C., Lindblom, P. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Experientia Supplementum 94 : 115-125. 2005

Experimental Cell Research

Introduction to the ECR special angiogenesis issue.
Claesson-Welsh, L. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Experimental Cell Research 319 (9): 1239. 15 May 2013

FASEB Journal

Therapeutic antibodies targeting angiomotin inhibit angiogenesis in vivo.
Levchenko, T., Veitonmäki, N., Lundkvist, A., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Ming, Y., Berggren, K., Kvanta, A., Carlsson, R. and Holmgren, L.
FASEB Journal 22 (3): 880-889. March 2008

FEMS Microbiology Letters

Localization of Legionella bacteria within ribosome-studded phagosomes is not restricted to Legionella pneumophila.
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Walz, M.J., Faigle, M., Northoff, H., Wolburg, H. and Neumeister, B.
FEMS Microbiology Letters 192 (1): 145-152. 1 November 2000

Frontiers in Cardiovascular Medicine

Brief research report: Quantitative analysis of potential coronary microvascular disease in suspected long-COVID syndrome.
Doeblin, P., Steinbeis, F., Scannell, C.M., Goetze, C., Al-Tabatabaee, S., Erley, J., Faragli, A., Pröpper, F., Witzenrath, M., Zoller, T., Stehning, C., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Sánchez-González, J., Alskaf, E., Kühne, T., Pieske, B. ORCID: https://orcid.org/0000-0002-6466-5306, Tschöpe, C., Chiribiri, A. and Kelle, S.
Frontiers in Cardiovascular Medicine 9 : 877416. 31 May 2022

Formation and maintenance of the natural bypass vessels of the brain.
Perovic, T. ORCID: https://orcid.org/0000-0003-2269-0738, Harms, C. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Frontiers in Cardiovascular Medicine 9 : 778773. 22 March 2022

Frontiers in Physiology

Endothelial cell orientation and polarity are controlled by shear stress and VEGF through distinct signaling pathways.
Vion, A.C. ORCID: https://orcid.org/0000-0002-2788-2512, Perovic, T. ORCID: https://orcid.org/0000-0003-2269-0738, Petit, C., Hollfinger, I. ORCID: https://orcid.org/0000-0002-6233-8395, Bartels-Klein, E., Frampton, E., Gordon, E., Claesson-Welsh, L. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Frontiers in Physiology 11 : 623769. 2 March 2021

Genes & Development

Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development.
Abramsson, A., Kurup, S., Busse, M., Yamada, S., Lindblom, P., Schallmeiner, E., Stenzel, D., Sauvaget, D., Ledin, J., Ringvall, M., Landegren, U., Kjellén, L., Bondjers, G., Li, J.P., Lindahl, U., Spillmann, D., Betsholtz, C. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Genes & Development 21 (3): 316-331. 1 February 2007

Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall.
Lindblom, P., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Liebner, S., Abramsson, A., Enge, M., Hellstrom, M., Backstrom, G., Fredriksson, S., Landegren, U., Nystrom, H.C., Bergstrom, G., Dejana, E., Ostman, A., Lindahl, P. and Betsholtz, C.
Genes & Development 17 (15): 1835-1840. 1 August 2003

Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis.
Ruhrberg, C. ORCID: https://orcid.org/0000-0002-3212-9381, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Golding, M., Watson, R., Ioannidou, S., Fujisawa, H., Betsholtz, C. and Shima, D.T.
Genes & Development 16 (20): 2684-2698. 15 October 2002

Genesis

Intron with transgenic marker (InTraM) facilitates high-throughput screening of endogenous gene reporter lines.
Collins, R.T. ORCID: https://orcid.org/0000-0002-1847-4517, Coxam, B. ORCID: https://orcid.org/0000-0003-1606-6373, Fechner, I. ORCID: https://orcid.org/0000-0002-0184-8324, Unterweger, I. ORCID: https://orcid.org/0000-0001-7041-8638, Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Meier, K. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Genesis 58 (10-11): e23391. November 2020

Glia

R- and B-cadherin expression defines subpopulations of glial cells involved in axonal guidance in the optic nerve head of the chicken.
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Rascher, G., Schuck, J., Weigold, U., Redies, C. and Wolburg, H.
Glia 31 (2): 131-143. August 2000

Differentiation of a unique macroglial cell type in the pecten oculi of the chicken.
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Schuck, J. and Wolburg, H.
Glia 28 (3): 201-214. December 1999

Health and Quality of Life Outcomes

Converting PROMIS®-29 v2.0 profile data to SF-36 physical and mental component summary scores in patients with cardiovascular disorders.
Liegl, G., Fischer, F.H., Martin, C.N., Rönnefarth, M., Blumrich, A., Ahmadi, M., Boldt, L.H., Eckardt, K.U., Endres, M., Edelmann, F., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Grittner, U., Haghikia, A., Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Landmesser, U., Leistner, D., Mai, K., Kollmus-Heege, J., Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Nolte, C.H., Piper, S.K., Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142, Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X, Rattan, S., Rohrpasser-Napierkowski, Ira, Schönrath, K., Schulz-Menger, J. ORCID: https://orcid.org/0000-0003-3100-1092, Schweizerhof, O., Spranger, J. ORCID: https://orcid.org/0000-0002-8900-4467, Weber, J.E., Witzenrath, M., Schmidt, S. and Rose, M.
Health and Quality of Life Outcomes 22 (1): 64. 15 August 2024

Human Molecular Genetics

Lack of CCM1 induces hypersprouting and impairs response to flow.
Mleynek, T.M., Chan, A.C., Redd, M., Gibson, C.C., Davis, C.T., Shi, D.S., Chen, T., Carter, K.L., Ling, J., Blanco, R., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Whitehead, K. and Li, D.Y.
Human Molecular Genetics 23 (23): 6223-6234. 1 December 2014

International Journal of Cancer

Glioma-derived galectin-1 regulates innate and adaptive antitumor immunity.
Verschuere, T., Toelen, J., Maes, W., Poirier, F., Boon, L., Tousseyn, T., Mathivet, T., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Mathieu, V., Kiss, R., Lefranc, F., Van Gool, S.W. and De Vleeschouwer, S.
International Journal of Cancer 134 (4): 873-884. 15 February 2014

International Journal of Molecular Sciences

Vascular and liver homeostasis in juvenile mice require endothelial cyclic AMP-dependent protein kinase A.
Nedvetsky, P.I. ORCID: https://orcid.org/0000-0002-0572-9074, Cornelissen, I., Mathivet, T. ORCID: https://orcid.org/0000-0001-7761-1684, Bouleti, C., Ou, P., Baatsen, P. ORCID: https://orcid.org/0000-0003-4500-581X, Zhao, X. ORCID: https://orcid.org/0000-0002-4048-6813, Schuit, F., Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Mostov, K.E. ORCID: https://orcid.org/0000-0002-8123-6247 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
International Journal of Molecular Sciences 23 (19): 11419. 27 September 2022

International Review of Cytology

The pecten oculi of the chicken: a model system for vascular differentiation and barrier maturation.
Wolburg, H., Liebner, S., Reichenbach, A. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
International Review of Cytology 187 : 111-159. 1999

IntraVital

Intravital imaging reveals conversion between distinct tumor vascular morphologies and localized vascular response to Sunitinib.
Manning, C.S., Jenkins, R., Hooper, S., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Marais, R., Adams, S., Adams, R.H., van Rheenen, J. and Sahai, E.
IntraVital 2 (1): e24790. January 2013

JBMR Plus

Directed vascularization in bone regeneration requires bone marrow reconstitution.
Mehl, Julia ORCID: https://orcid.org/0000-0002-8279-7142, Thiele, Tobias, Ellinghaus, Agnes, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384 and Duda, Georg N.
JBMR Plus 9 (12): ziaf162. December 2025

JCI Insight

Endothelial deletion of adipose triglyceride lipase protects against heart failure with preserved ejection fraction.
Schwanbeck, J., Stahnke, M., Eberlein, A., Goeritzer, M., Schulze, A., Pernitsch, D., Kolb, D., Grabner, G.F., Bartolomaeus, T.U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Schiattarella, G.G. ORCID: https://orcid.org/0000-0002-7582-7171, Cocera Ortega, L., López-Anguita, N. ORCID: https://orcid.org/0000-0003-3373-7191, Kershaw, E.E., Maatz, H. ORCID: https://orcid.org/0000-0002-9232-6272, Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Zechner, R., Foryst-Ludwig, A. and Kintscher, U.
JCI Insight 10 (5): e187145. 10 March 2025

Journal of Cell Biology

Blood flow meets mitophagy.
Akmeriç, E.B. ORCID: https://orcid.org/0000-0003-4463-8017 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Journal of Cell Biology 221 (7): e202206033. 4 July 2022

Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression.
Vion, A.C. ORCID: https://orcid.org/0000-0002-2788-2512, Alt, S. ORCID: https://orcid.org/0000-0003-1877-2968, Klaus-Bergmann, A. ORCID: https://orcid.org/0000-0002-1164-3322, Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Zheng, T. ORCID: https://orcid.org/0000-0003-3385-7353, Perovic, T. ORCID: https://orcid.org/0000-0003-2269-0738, Hammoutene, A., Oliveira, M.B. ORCID: https://orcid.org/0000-0002-6635-3963, Bartels-Klein, E., Hollfinger, I. ORCID: https://orcid.org/0000-0002-6233-8395, Rautou, P.E. ORCID: https://orcid.org/0000-0001-9567-1859, Bernabeu, M.O. ORCID: https://orcid.org/0000-0002-6456-3756 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Journal of Cell Biology 217 (5): 1651-1665. 7 May 2018

Blood flow boosts BMP signaling to keep vessels in shape.
Franco, C.A. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Journal of Cell Biology 214 (7): 793-795. 26 September 2016

Wnt/β-catenin signaling controls development of the blood-brain barrier.
Liebner, S., Corada, M., Bangsow, T., Babbage, J., Taddei, A., Czupalla, C.J., Reis, M., Felici, A., Wolburg, H., Fruttiger, M. ORCID: https://orcid.org/0000-0002-6962-5485, Taketo, M.M., von Melchner, H., Plate, K.H., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Dejana, E.
Journal of Cell Biology 183 (3): 409-417. 3 November 2008

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia.
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Golding, M., Fruttiger, M., Ruhrberg, C., Lundkvist, A., Abramsson, A., Jeltsch, M., Mitchell, C., Alitalo, K., Shima, D. and Betsholtz, C.
Journal of Cell Biology 161 (6): 1163-1177. 23 June 2003

Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis.
Hellström, M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Kalén, M., Li, X., Eriksson, U., Wolburg, H. and Betsholtz, C.
Journal of Cell Biology 153 (3): 543-553. 30 April 2001

Journal of Cell Science

DLC1 is a direct target of activated YAP/TAZ that drives collective migration and sprouting angiogenesis.
van der Stoel, M., Schimmel, L., Nawaz, K., van Stalborch, A.M., de Haan, A., Klaus-Bergmann, A. ORCID: https://orcid.org/0000-0002-1164-3322, Valent, E.T., Koenis, D.S., van Nieuw Amerongen, G.P., de Vries, C.J., de Waard, V., Gloerich, M., van Buul, J.D. and Huveneers, S.
Journal of Cell Science 133 (3): jcs239947. 12 February 2020

Journal of Clinical Investigation

Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice.
Fu, J., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, McDaniel, J.M., Xia, B., Liu, X., Ivanciu, L., Ny, A., Hermans, K., Silasi-Mansat, R. ORCID: https://orcid.org/0000-0001-9590-6160, McGee, S., Nye, E., Ju, T., Ramirez, M.I. ORCID: https://orcid.org/0000-0001-6294-4419, Carmeliet, P., Cummings, R.D., Lupu, F. ORCID: https://orcid.org/0000-0003-1249-9278 and Xia, L.
Journal of Clinical Investigation 118 (11): 3725-3737. November 2008

Pericytes limit tumor cell metastasis.
Xian, X., Håkansson, J., Ståhlberg, A., Lindblom, P., Betsholtz, C., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Semb, H.
Journal of Clinical Investigation 116 (3): 642-651. 1 March 2006

Journal of Controlled Release

Development of siRNA-loaded chitosan nanoparticles targeting Galectin-1 for the treatment of glioblastoma multiforme via intranasal administration.
Van Woensel, M., Wauthoz, N., Rosière, R., Mathieu, V., Kiss, R., Lefranc, F., Steelant, B., Dilissen, E., Van Gool, S.W., Mathivet, T., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Amighi, K. and De Vleeschouwer, S.
Journal of Controlled Release 227 : 71-81. 10 April 2016

Journal of Experimental Medicine

Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis.
Soler, A., Serra, H., Pearce, W., Angulo, A., Guillermet-Guibert, J., Friedman, L.S., Viñals, F., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Casanovas, O., Graupera, M. and Vanhaesebroeck, B.
Journal of Experimental Medicine 210 (10): 1937-1945. 23 September 2013

Journal of Molecular Medicine

A map of human circular RNAs in clinically relevant tissues.
Maass, P.G. ORCID: https://orcid.org/0000-0002-2742-8301, Glažar, P. ORCID: https://orcid.org/0000-0003-0842-0088, Memczak, S. ORCID: https://orcid.org/0000-0001-9518-7135, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Hollfinger, I. ORCID: https://orcid.org/0000-0002-6233-8395, Schreyer, L., Sauer, A.V., Toka, O., Aiuti, A., Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199 and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
Journal of Molecular Medicine 95 (11): 1179-1189. November 2017

Pericytes: gatekeepers in tumour cell metastasis?
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Semb, H. ORCID: https://orcid.org/0000-0002-6747-787X
Journal of Molecular Medicine 86 (2): 135-144. February 2008

Journal of Theoretical Biology

Agent-based simulation of notch-mediated tip cell selection in angiogenic sprout initialisation.
Bentley, K. ORCID: https://orcid.org/0000-0002-9391-659X, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Bates, P.A. ORCID: https://orcid.org/0000-0003-0621-0925
Journal of Theoretical Biology 250 (1): 25-36. 7 January 2008

Journal of the American Heart Association

Loss of endothelial YAP/TAZ reduces the size of chronic stroke lesions and alters the endothelial environment.
Göttert, Ria ORCID: https://orcid.org/0000-0003-4756-7381, Kikhia, Majed ORCID: https://orcid.org/0000-0002-7719-9455, Herzog, Marie-Louise, Pan, Wen, Klaus-Bergmann, Alexandra ORCID: https://orcid.org/0000-0002-1164-3322, Weiner, January ORCID: https://orcid.org/0000-0003-1438-7819, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Knauss, Samuel ORCID: https://orcid.org/0000-0002-3046-9075, Kronenberg, Golo ORCID: https://orcid.org/0000-0002-5310-9849, Bader, Michael ORCID: https://orcid.org/0000-0003-4780-4164, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384, Endres, Matthias ORCID: https://orcid.org/0000-0001-6520-3720 and Gertz, Karen ORCID: https://orcid.org/0000-0002-1203-641X
Journal of the American Heart Association 15 (6): e040079. 17 March 2026

Journal of the Royal Society Interface

Association between erythrocyte dynamics and vessel remodelling in developmental vascular networks.
Zhou, Q. ORCID: https://orcid.org/0000-0003-3560-2311, Perovic, T. ORCID: https://orcid.org/0000-0003-2269-0738, Fechner, I. ORCID: https://orcid.org/0000-0002-0184-8324, Edgar, L.T., Hoskins, P.R., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Krüger, T. ORCID: https://orcid.org/0000-0003-2934-2699 and Bernabeu, M.O. ORCID: https://orcid.org/0000-0002-6456-3756
Journal of the Royal Society Interface 18 (179): 20210113. June 2021

Computer simulations reveal complex distribution of haemodynamic forces in a mouse retina model of angiogenesis.
Bernabeu, M.O., Jones, M.L., Nielsen, J.H., Krüger, T., Nash, R.W., Groen, D., Schmieschek, S., Hetherington, J., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Franco, C.A. and Coveney, P.V.
Journal of the Royal Society Interface 11 (99): 20140543. 6 October 2014

Methods in Molecular Biology

Imaging glioma progression by intravital microscopy.
Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Matsumoto, K. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Methods in Molecular Biology 1862 : 227-243. 2019

Imaging of endothelial cell dynamic behavior in zebrafish.
Coxam, B. ORCID: https://orcid.org/0000-0003-1606-6373 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Methods in Molecular Biology 1846 : 181-195. 2018

Microsystems & Nanoengineering

A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions.
Fonseca, C.G. ORCID: https://orcid.org/0000-0002-1978-0612, Silvério, V. ORCID: https://orcid.org/0000-0002-8368-3374, Barata, D. ORCID: https://orcid.org/0000-0002-8753-7403, Giese, W. ORCID: https://orcid.org/0000-0003-0872-0929, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Cardoso, S. ORCID: https://orcid.org/0000-0001-6913-6529 and Franco, C.A. ORCID: https://orcid.org/0000-0002-2861-3883
Microsystems & Nanoengineering 9 : 114. 15 September 2023

Molecular Biology of the Cell

Three-dimensional superresolution fluorescence microscopy maps the variable molecular architecture of the nuclear pore complex.
Sabinina, V.J., Hossain, M.J., Hériché, J.K., Hoess, P., Nijmeijer, B., Mosalaganti, S., Kueblbeck, M., Callegari, A., Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Beck, M., Ries, J. and Ellenberg, J.
Molecular Biology of the Cell 32 (17): 1523-1533. 15 August 2021

Molecular and Cellular Biology

Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking αv integrins.
McCarty, J.H., Monahan-Earley, R.A., Brown, L.F., Keller, M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Rubin, K., Shani, M., Dvorak, H.F., Wolburg, H., Bader, B.L., Dvorak, A.M. and Hynes, R.O.
Molecular and Cellular Biology 22 (21): 7667-7677. November 2002

Nature

Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.
Messal, H.A., Alt, S. ORCID: https://orcid.org/0000-0003-1877-2968, Ferreira, R.M.M., Gribben, C., Wang, V.M.Y., Cotoi, C.G., Salbreux, G. and Behrens, A.
Nature 566 (7742): 126-130. 7 February 2019

A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
Elling, U., Wimmer, R.A., Leibbrandt, A., Burkard, T., Michlits, G., Leopoldi, A., Micheler, T., Abdeen, D., Zhuk, S., Aspalter, I.M., Handl, C., Liebergesell, J., Hubmann, M., Husa, A.M., Kinzer, M., Schuller, N., Wetzel, E., van de Loo, N., Martinez, J.A.Z., Estoppey, D., Riedl, R., Yang, F., Fu, B., Dechat, T., Ivics, Z. ORCID: https://orcid.org/0000-0002-7803-6658, Agu, C.A., Bell, O., Blaas, D., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Hoepfner, D., Stark, A. and Penninger, J.M.
Nature 550 (7674): 114-118. 5 October 2017

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T. ORCID: https://orcid.org/0000-0003-3309-5141, Friese, C., Arina, A., Idel, C., Briesemeister, D. ORCID: https://orcid.org/0000-0002-5673-8552, Rothe, M. ORCID: https://orcid.org/0000-0002-6813-4705, Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Patone, G. ORCID: https://orcid.org/0000-0002-7242-0341, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Sommermeyer, D., Engels, B. ORCID: https://orcid.org/0000-0001-9682-2954, Leisegang, M. ORCID: https://orcid.org/0000-0003-3692-7142, Textor, A. ORCID: https://orcid.org/0000-0002-9952-4650, Fehling, H.J., Fruttiger, M., Lohoff, M., Herrmann, A., Yu, H., Weichselbaum, R., Uckert, W., Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Schreiber, H. and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Nature 545 (7652): 98-102. 4 May 2017

FOXO1 couples metabolic activity and growth state in the vascular endothelium.
Wilhelm, K., Happel, K., Eelen, G., Schoors, S., Oellerich, M.F., Lim, R., Zimmermann, B., Aspalter, I.M., Franco, C.A., Boettger, T., Braun, T., Fruttiger, M., Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Keller, C., Brüning, J.C., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Carmeliet, P. and Potente, M. ORCID: https://orcid.org/0000-0002-5689-0036
Nature 529 (7585): 216-220. 14 January 2016

Fatty acid carbon is essential for dNTP synthesis in endothelial cells.
Schoors, S., Bruning, U., Missiaen, R., Queiroz, K.C.S., Borgers, G., Elia, I., Zecchin, A., Cantelmo, A.R., Christen, S., Goveia, J., Heggermont, W., Goddé, L., Vinckier, S., Van Veldhoven, P.P., Eelen, G., Schoonjans, L., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Dewerchin, M., Baes, M., De Bock, K., Ghesquière, B., Lunt, S.Y., Fendt, S.M. and Carmeliet, P.
Nature 520 (7546): 192-197. 9 April 2015

Tissue engineering: Blood vessels on a chip.
Franco, C. ORCID: https://orcid.org/0000-0002-2861-3883 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Nature 488 (7412): 465-466. 23 August 2012

Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.
Stefater, J.A., Lewkowich, I., Rao, S., Mariggi, G., Carpenter, A.C., Burr, A.R., Fan, J., Ajima, R., Molkentin, J.D., Williams, B.O., Wills-Karp, M., Pollard, J.W., Yamaguchi, T., Ferrara, N., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Lang, R.A.
Nature 474 (7352): 511-515. 23 June 2011

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase.
Guarani, V., Deflorian, G., Franco, C.A., Krüger, M., Phng, L.K., Bentley, K., Toussaint, L., Dequiedt, F., Mostoslavsky, R., Schmidt, M.H.H., Zimmermann, B., Brandes, R.P., Mione, M., Westphal, C.H., Braun, T., Zeiher, A.M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Dimmeler, S. and Potente, M. ORCID: https://orcid.org/0000-0002-5689-0036
Nature 473 (7346): 234-238. 12 May 2011

Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration.
Graupera, M. ORCID: https://orcid.org/0000-0003-4608-4185, Guillermet-Guibert, J. ORCID: https://orcid.org/0000-0003-3173-4907, Foukas, L.C., Phng, L.K., Cain, R.J., Salpekar, A., Pearce, W., Meek, S., Millan, J., Cutillas, P.R. ORCID: https://orcid.org/0000-0002-3426-2274, Smith, A.J.H., Ridley, A.J. ORCID: https://orcid.org/0000-0001-8186-5708, Ruhrberg, C. ORCID: https://orcid.org/0000-0002-3212-9381, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Vanhaesebroeck, B.
Nature 453 (7195): 662-666. 29 May 2008

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
Hellström, M. ORCID: https://orcid.org/0000-0002-7088-9533, Phng, L.K., Hofmann, J.J., Wallgard, E., Coultas, L., Lindblom, P., Alva, J., Nilsson, A.K., Karlsson, L., Gaiano, N., Yoon, K. ORCID: https://orcid.org/0000-0002-2361-9039, Rossant, J., Iruela-Arispe, M.L., Kalén, M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Betsholtz, C.
Nature 445 (7129): 776-780. 15 February 2007

Nature Cardiovascular Research

Mechanosensitive PIEZO2 channels shape coronary artery development.
Pampols-Perez, M. ORCID: https://orcid.org/0009-0008-1619-204X, Fürst, C., Sánchez-Carranza, O. ORCID: https://orcid.org/0000-0002-8745-5176, Cano, E. ORCID: https://orcid.org/0000-0003-1091-8934, Garcia-Contreras, J.A., Mais, L. ORCID: https://orcid.org/0000-0002-9281-2668, Luo, W. ORCID: https://orcid.org/0000-0001-5202-8855, Raimundo, S. ORCID: https://orcid.org/0009-0000-3353-5456, Lindberg, E.L. ORCID: https://orcid.org/0000-0002-2979-433X, Taube, M., Heuser, A. ORCID: https://orcid.org/0000-0002-3334-960X, Sporbert, A. ORCID: https://orcid.org/0000-0002-3738-1295, Kainmueller, D. ORCID: https://orcid.org/0000-0002-9830-2415, Bernabeu, M.O., Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352 and Hammes, A. ORCID: https://orcid.org/0000-0003-1663-8378
Nature Cardiovascular Research 4 (7): 921-937. July 2025

Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis.
Jin, Y. ORCID: https://orcid.org/0000-0001-9704-973X, Ding, Y. ORCID: https://orcid.org/0000-0003-4672-7611, Richards, M., Kaakinen, M., Giese, W. ORCID: https://orcid.org/0000-0003-0872-0929, Baumann, E. ORCID: https://orcid.org/0000-0002-7804-4885, Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Rosa, A. ORCID: https://orcid.org/0000-0003-4505-9260, Nordling, S., Schimmel, L., Akmeriç, E.B. ORCID: https://orcid.org/0000-0003-4463-8017, Pena, A., Nwadozi, E., Jamalpour, M., Holstein, K. ORCID: https://orcid.org/0000-0003-1540-8378, Sáinz-Jaspeado, M., Bernabeu, M.O. ORCID: https://orcid.org/0000-0002-6456-3756, Welsh, M. ORCID: https://orcid.org/0000-0002-5467-9755, Gordon, E., Franco, C.A. ORCID: https://orcid.org/0000-0002-2861-3883, Vestweber, D., Eklund, L., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Claesson-Welsh, L. ORCID: https://orcid.org/0000-0003-4275-2000
Nature Cardiovascular Research 1 (12): 1156–1173. December 2022

Nature Cell Biology

Blood flow drives lumen formation by inverse membrane blebbing during angiogenesis in vivo.
Gebala, V., Collins, R. ORCID: https://orcid.org/0000-0002-1847-4517, Geudens, I., Phng, L.K. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Nature Cell Biology 18 (4): 443-450. April 2016

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis.
Bentley, K., Franco, C.A., Philippides, A., Blanco, R., Dierkes, M., Gebala, V., Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Jones, M., Aspalter, I.M., Cagna, G., Weström, S., Claesson-Welsh, L., Vestweber, D. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Nature Cell Biology 16 (4): 309-321. April 2014

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.
Tammela, T., Zarkada, G., Nurmi, H., Jakobsson, L. ORCID: https://orcid.org/0000-0001-7956-587X, Heinolainen, K., Tvorogov, D., Zheng, W. ORCID: https://orcid.org/0000-0003-0021-6672, Franco, C.A. ORCID: https://orcid.org/0000-0002-2861-3883, Murtomäki, A., Aranda, E., Miura, N., Ylä-Herttuala, S. ORCID: https://orcid.org/0000-0001-7593-2708, Fruttiger, M., Mäkinen, T. ORCID: https://orcid.org/0000-0002-9338-1257, Eichmann, A., Pollard, J.W., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Alitalo, K. ORCID: https://orcid.org/0000-0002-7331-0902
Nature Cell Biology 13 (10): 1202-1213. 11 September 2011

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting.
Jakobsson, L. ORCID: https://orcid.org/0000-0001-7956-587X, Franco, C.A. ORCID: https://orcid.org/0000-0002-2861-3883, Bentley, K. ORCID: https://orcid.org/0000-0002-9391-659X, Collins, R.T., Ponsioen, B., Aspalter, I.M., Rosewell, I., Busse, M., Thurston, G., Medvinsky, A., Schulte-Merker, S. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Nature Cell Biology 12 (10): 943-953. October 2010

Nature Communications

Polarity-JaM: an image analysis toolbox for cell polarity, junction and morphology quantification.
Giese, W. ORCID: https://orcid.org/0000-0003-0872-0929, Albrecht, J.P. ORCID: https://orcid.org/0000-0002-3792-9695, Oppenheim, O. ORCID: https://orcid.org/0000-0002-5299-3193, Akmeriç, E.B. ORCID: https://orcid.org/0000-0003-4463-8017, Kraxner, J. ORCID: https://orcid.org/0000-0002-3515-7468, Schmidt, D. ORCID: https://orcid.org/0000-0002-8621-9438, Harrington, K.I. ORCID: https://orcid.org/0000-0002-7237-1973 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Nature Communications 16 (1): 1474. 8 February 2025

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.
Angulo-Urarte, A., Casado, P. ORCID: https://orcid.org/0000-0002-4207-9349, Castillo, S.D., Kobialka, P., Kotini, M.P., Figueiredo, A.M., Castel, P., Rajeeve, V., Milà-Guasch, M., Millan, J., Wiesner, C., Serra, H., Muixi, L., Casanovas, O. ORCID: https://orcid.org/0000-0002-4298-3995, Viñals, F., Affolter, M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Huveneers, S., Belting, H.G. ORCID: https://orcid.org/0000-0002-1538-4364, Cutillas, P.R. and Graupera, M.
Nature Communications 9 (1): 4826. 16 November 2018

The endothelial transcription factor ERG mediates angiopoietin-1-dependent control of notch signalling and vascular stability.
Shah, A.V., Birdsey, G.M., Peghaire, C., Pitulescu, M.E., Dufton, N.P., Yang, Y., Weinberg, I., Osuna Almagro, L., Payne, L., Mason, J.C., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Adams, R.H. and Randi, A.M.
Nature Communications 8 : 16002. 11 July 2017

Glycolytic regulation of cell rearrangement in angiogenesis.
Cruys, B., Wong, B.W., Kuchnio, A., Verdegem, D., Cantelmo, A. R., Conradi, L.C., Vandekeere, S., Bouché, A., Cornelissen, I., Vinckier, S., Merks, R.M.H., Dejana, E., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Dewerchin, M., Bentley, K. and Carmeliet, P.
Nature Communications 7 : 12240. 20 July 2016

PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.
Serra, H., Chivite, I., Angulo-Urarte, A., Soler, A., Sutherland, J.D., Arruabarrena-Aristorena, A., Ragab, A., Lim, R., Malumbres, M., Fruttiger, M., Potente, M. ORCID: https://orcid.org/0000-0002-5689-0036, Serrano, M., Fabra, A., Vinals, F., Casanovas, O., Pandolfi, P.P., Bigas, A., Carracedo, A., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Graupera, M.
Nature Communications 6 : 7935. 31 July 2015

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.
Aspalter, I.M., Gordon, E., Dubrac, A., Ragab, A., Narloch, J., Vizán, P., Geudens, I., Collins, R.T. ORCID: https://orcid.org/0000-0002-1847-4517, Franco, C.A., Abrahams, C.L., Thurston, G., Fruttiger, M., Rosewell, I., Eichmann, A. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Nature Communications 6 : 7264. 17 June 2015

Nature Medicine

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Jones, C.A., London, N.R., Chen, H. ORCID: https://orcid.org/0000-0003-0676-4610, Park, K.W. ORCID: https://orcid.org/0000-0003-2771-249X, Sauvaget, D., Stockton, R.A., Wythe, J.D., Suh, W., Larrieu-Lahargue, F., Mukouyama, Y.S. ORCID: https://orcid.org/0000-0002-9084-4922, Lindblom, P., Seth, P., Frias, A., Nishiya, N., Ginsberg, M.H., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Zhang, K. and Li, D.Y.
Nature Medicine 14 (4): 448-453. April 2008

Nature Metabolism

A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth.
Ong, Y.T., Andrade, J. ORCID: https://orcid.org/0000-0002-4577-8620, Armbruster, M., Shi, C. ORCID: https://orcid.org/0000-0002-8645-2002, Castro, M. ORCID: https://orcid.org/0000-0001-7851-7446, Costa, A.S.H., Sugino, T., Eelen, G., Zimmermann, B., Wilhelm, K., Lim, J. ORCID: https://orcid.org/0000-0002-1740-8710, Watanabe, S., Guenther, S., Schneider, A., Zanconato, F., Kaulich, M. ORCID: https://orcid.org/0000-0002-9528-8822, Pan, D. ORCID: https://orcid.org/0000-0003-2890-4645, Braun, T. ORCID: https://orcid.org/0000-0002-6165-4804, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Efeyan, A. ORCID: https://orcid.org/0000-0002-3806-6799, Carmeliet, P. ORCID: https://orcid.org/0000-0001-7961-1821, Piccolo, S. ORCID: https://orcid.org/0000-0002-1600-3092, Grosso, A.R. and Potente, M. ORCID: https://orcid.org/0000-0002-5689-0036
Nature Metabolism 4 (6): 672-682. June 2022

Nature Protocols

Quantitative assessment of angiogenesis, perfused blood vessels and endothelial tip cells in the postnatal mouse brain.
Wälchli, T., Mateos, J.M., Weinman, O., Babic, D., Regli, L., Hoerstrup, S.P., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Schwab, M.E. and Vogel, J.
Nature Protocols 10 (1): 53-74. January 2015

Neuro-Oncology Advances

Long-lived tumor-associated macrophages in glioma.
Georgieva, P.B. ORCID: https://orcid.org/0000-0002-6347-2297, Mathivet, T., Alt, S. ORCID: https://orcid.org/0000-0003-1877-2968, Giese, W. ORCID: https://orcid.org/0000-0003-0872-0929, Riva, M., Balcer, M. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Neuro-Oncology Advances 2 (1): vdaa127. 9 November 2020

Neuron

Wiring the vascular network with neural cues: a CNS perspective.
Waächli, T., Wacker, A., Frei, K., Regli, L., Schwab, M.E., Hoerstrup, S.P., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Engelhardt, B.
Neuron 87 (2): 271-296. 15 July 2015

Novartis Foundation Symposium

Growth factor gradients in vascular patterning.
Lundkvist, A., Lee, S., Iruela-Arispe, L., Betsholtz, C. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Novartis Foundation Symposium 283 : 194-201. 20 July 2007

Nutrients

Role of vitamin A/retinoic acid in regulation of embryonic and adult hematopoiesis.
Canete, A., Cano, E. ORCID: https://orcid.org/0000-0003-1091-8934, Munoz-Chapuli, R. and Carmona, R.
Nutrients 9 (2): 159. 20 February 2017

Organogenesis

VEGF and endothelial guidance in angiogenic sprouting.
Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Organogenesis 4 (4): 241-246. October 2008

PLoS Biology

Dynamic endothelial cell rearrangements drive developmental vessel regression.
Franco, C.A., Jones, M.L., Bernabeu, M.O., Geudens, I., Mathivet, T., Rosa, A., Lopes, F.M., Lima, A.P., Ragab, A., Collins, R.T. ORCID: https://orcid.org/0000-0002-1847-4517, Phng, L.K., Coveney, P.V. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
PLoS Biology 13 (4): e1002125. 17 April 2015

PLoS Computational Biology

External mechanical loading overrules cell-cell mechanical communication in sprouting angiogenesis during early bone regeneration.
Dazzi, C. ORCID: https://orcid.org/0000-0002-5435-0554, Mehl, J., Benamar, M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Knaus, P., Duda, G.N. and Checa, S. ORCID: https://orcid.org/0000-0002-1444-5858
PLoS Computational Biology 19 (11): e1011647. 13 November 2023

On the preservation of vessel bifurcations during flow-mediated angiogenic remodelling.
Edgar, L.T., Franco, C.A. ORCID: https://orcid.org/0000-0002-2861-3883, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Bernabeu, M.O. ORCID: https://orcid.org/0000-0002-6456-3756
PLoS Computational Biology 17 (2): e1007715. 4 February 2021

Tipping the balance: robustness of tip cell selection, migration and fusion in angiogenesis.
Bentley, K., Mariggi, G., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Bates, P.A.
PLoS Computational Biology 5 (10): e1000549. 30 October 2009

PLoS ONE

Visualization of endothelial actin cytoskeleton in the mouse retina.
Fraccaroli, A., Franco, C.A., Rognoni, E., Neto, F., Rehberg, M., Aszodi, A., Wedlich-Söldner, R., Pohl, U., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Montanez, E.
PLoS ONE 7 (10): e47488. 24 October 2012

N-CAM exhibits a regulatory function in pathological angiogenesis in oxygen induced retinopathy.
Håkansson, J., Ståhlberg, A., Wolfhagen Sand, F., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Semb, H.
PLoS ONE 6 (10): e26026. 17 October 2011

A two-way communication between microglial cells and angiogenic sprouts regulates angiogenesis in aortic ring cultures.
Rymo, S.F., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Wolfhagen Sand, F., Lang, R., Uv, A. and Betsholtz, C.
PLoS ONE 6 (1): e15846. 10 January 2011

Imaging transient blood vessel fusion events in zebrafish by correlative volume electron microscopy.
Armer, H.E.J., Mariggi, G., Png, K.M.Y., Genoud, C., Monteith, A.G., Bushby, A.J., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Collinson, L.M.
PLoS ONE 4 (11): e7716. 6 November 2009

Photoacoustics

A backward-mode optical-resolution photoacoustic microscope for 3D imaging using a planar Fabry-Pérot sensor.
Baumann, E. ORCID: https://orcid.org/0000-0002-7804-4885, Pohle, U., Zhang, E., Allen, T. ORCID: https://orcid.org/0000-0002-4139-0231, Villringer, C. ORCID: https://orcid.org/0000-0001-5158-2424, Pulwer, S., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Laufer, J.
Photoacoustics 24 : 100293. December 2021

Proceedings of SPIE

Development of a backward-mode photoacoustic microscope using a Fabry-Pérot sensor.
Pohle, U., Baumann, E. ORCID: https://orcid.org/0000-0002-7804-4885, Pulwer, S., Villringer, C., Zhang, E.Z., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384 and Laufer, J.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA. 6 March 2019

Proceedings of the National Academy of Sciences of the United States of America

Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections.
Cano, E. ORCID: https://orcid.org/0000-0003-1091-8934, Carmona, R., Ruiz-Villalba, A., Rojas, A., Chau, Y.Y., Wagner, K.D., Wagner, N., Hastie, N.D., Munoz-Chapuli, R. and Perez-Pomares, J.M.
Proceedings of the National Academy of Sciences of the United States of America 113 (3): 656-661. 19 January 2016

Progress in Neurobiology

Astrocyte-derived Wnt growth factors are required for endothelial blood-brain barrier maintenance.
Guérit, S., Fidan, E., Macas, J., Czupalla, C.J. ORCID: https://orcid.org/0000-0002-0653-8886, Figueiredo, R. ORCID: https://orcid.org/0000-0003-3024-1254, Vijikumar, A., Yalcin, B.H., Thom, S., Winter, P., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Devraj, K. ORCID: https://orcid.org/0000-0002-5005-3413 and Liebner, S. ORCID: https://orcid.org/0000-0002-4656-2258
Progress in Neurobiology 199 : 101937. April 2021

Scientific Reports

Sensitization of glioblastoma tumor micro-environment to chemo- and immunotherapy by Galectin-1 intranasal knock-down strategy.
Van Woensel, M., Mathivet, T., Wauthoz, N., Rosière, R., Garg, A.D., Agostinis, P., Mathieu, V., Kiss, R., Lefranc, F., Boon, L., Belmans, J., Van Gool, S.W., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Amighi, K. and De Vleeschouwer, S.
Scientific Reports 7 (1): 1217. 27 April 2017

Seminars in Cell & Developmental Biology

Mesothelial-mesenchymal transitions in embryogenesis.
Carmona, R. ORCID: https://orcid.org/0000-0002-9686-473X, Ariza, L., Cano, E. ORCID: https://orcid.org/0000-0003-1091-8934, Jiménez-Navarro, M. and Muñoz-Chápuli, R.
Seminars in Cell & Developmental Biology 92 : 37-44. August 2019

Translational Stroke Research

The genetic basis of Moyamoya disease.
Mertens, R., Graupera, M., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Bersano, A., Tournier-Lasserve, E., Mensah, M.A., Mundlos, S. and Vajkoczy, P. ORCID: https://orcid.org/0000-0003-4350-392X
Translational Stroke Research 13 (1): 25-45. February 2022

bioRxiv

Endothelial YAP/TAZ rewiring under cardiometabolic stress drives sex-divergent vascular remodeling in heart failure with preserved ejection fraction.
Klaus-Bergmann, Alexandra ORCID: https://orcid.org/0000-0002-1164-3322, Sievers, Laura Katharina ORCID: https://orcid.org/0000-0002-4677-5181, Versnjak, Jakob, Koch, Katharina, Nawara, Tomasz ORCID: https://orcid.org/0000-0002-4801-4095, Bartels-Klein, Eireen, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Weiner 3rd, January ORCID: https://orcid.org/0000-0003-1438-7819, Meier, Katja, Hollfinger, Irene ORCID: https://orcid.org/0000-0002-6233-8395, Kamer, Ilona, Taube, Martin, Heuser, Arnd ORCID: https://orcid.org/0000-0002-3334-960X, Borodina, Tatiana ORCID: https://orcid.org/0000-0002-6978-016X, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Potente, Michael ORCID: https://orcid.org/0000-0002-5689-0036, Landmesser, Ulf ORCID: https://orcid.org/0000-0002-0214-3203, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Kelm, Marcus, Muller, Dominik N. ORCID: https://orcid.org/0000-0003-3650-5644 and Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384
bioRxiv : 2026.05.07.723127. 13 May 2026

Disrupted endothelial cell-cell dynamics in ALK1 and SMAD4 deficiency drive arteriovenous malformations.
Hardman, David ORCID: https://orcid.org/0000-0001-9903-4443, Oppenheim, Olya ORCID: https://orcid.org/0000-0002-5299-3193, Giese, Wolfgang ORCID: https://orcid.org/0000-0003-0872-0929, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384 and Bernabeu, Miguel Oscar ORCID: https://orcid.org/0000-0002-6456-3756
bioRxiv : 2025.11.26.690643. 29 November 2025

Self-organized vascularized human liver spheroids: Serum-free culture conditions and use as tissue building blocks.
Filatova, Alina ORCID: https://orcid.org/0000-0002-2731-1963, Valentirovic Dann, Olivera, Schwarzkopf, Jennifer Bianca ORCID: https://orcid.org/0000-0001-9552-0794, Gerhardus, Jamina Sofie ORCID: https://orcid.org/0000-0001-6771-4145, Kaysan, Leon, Blaeser, Andreas, Straub, Beate Katharina, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384 and Nuber, Ulrike A.
bioRxiv : 2025.10.25.684548. 26 October 2025

Gene-specific endothelial programs drive AVM pathogenesis in SMAD4 and ALK1 loss-of-function.
Oppenheim, O. ORCID: https://orcid.org/0000-0002-5299-3193, Giese, W. ORCID: https://orcid.org/0000-0003-0872-0929, Park, H. ORCID: https://orcid.org/0000-0002-3671-8618, Baumann, E. ORCID: https://orcid.org/0000-0002-7804-4885, Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Eichmann, A. ORCID: https://orcid.org/0000-0001-5563-210X and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
bioRxiv : 2025.01.03.631070v3. 18 October 2025

Isogenic monocytes improve the responsiveness of hiPSC cardiac spheroids to cardiac stressors.
Strässler, Elisabeth T. ORCID: https://orcid.org/0000-0002-5286-9686, Kessler, Elise L., van Vliet, Emile F., Chirico, Nino, Na, Ellen, Cai, Qingqing, van Mil, Alain, Schiattarella, Gabriele G. ORCID: https://orcid.org/0000-0002-7582-7171, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384, Kränkel, Nicolle, de Jager, Saskia C.A., Sluijter, Joost P.G. and Landmesser, Ulf ORCID: https://orcid.org/0000-0002-0214-3203
bioRxiv : 2025.10.16.682827. 16 October 2025

Mechanical strain activates planar cell polarity signaling to coordinate vascular cell dynamics.
Golbach, L., Saha, T., Odenthal-Schnittler, M. ORCID: https://orcid.org/0000-0001-8467-7585, Lücking, J., Velic, A., Akmeric, E.B. ORCID: https://orcid.org/0000-0003-4463-8017, Bornhorst, D. ORCID: https://orcid.org/0000-0003-4084-0250, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Gunawan, F. ORCID: https://orcid.org/0000-0002-5592-9680, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Macek, B. ORCID: https://orcid.org/0000-0002-1206-2458, Trappmann, B. ORCID: https://orcid.org/0000-0002-6260-4075, Schnittler, H.J. ORCID: https://orcid.org/0000-0001-6807-3343, Galic, M. ORCID: https://orcid.org/0000-0002-4493-2542 and Matis, M. ORCID: https://orcid.org/0000-0003-3972-1983
bioRxiv : 2024.06.25.600357. 26 June 2024

Reconstructing stochastic cell population trajectories reveals regulators and heterogeneity of endothelial flow-migration coupling driving vascular remodelling.
Giese, W. ORCID: https://orcid.org/0000-0003-0872-0929, Rosa, A. ORCID: https://orcid.org/0000-0003-4505-9260, Baumann, E. ORCID: https://orcid.org/0000-0002-7804-4885, Oppenheim, O. ORCID: https://orcid.org/0000-0002-5299-3193, Akmeriç, E.B. ORCID: https://orcid.org/0000-0003-4463-8017, Andrade, S., Hollfinger, I. ORCID: https://orcid.org/0000-0002-6233-8395, Bartels-Klein, E., Alt, S. ORCID: https://orcid.org/0000-0003-1877-2968 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
bioRxiv : 2023.05.30.542799v3. 11 August 2023

Emerging single cell endothelial heterogeneity supports sprouting tumour angiogenesis and growth.
Matsumoto, K., Rambow, F., Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Mathivet, T., Qian, J., Giese, W. ORCID: https://orcid.org/0000-0003-0872-0929, He, L., Lambrechts, D., Zhou, B. ORCID: https://orcid.org/0000-0001-5278-5522, Betsholtz, C., Marine, J.C. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
bioRxiv : 2021.06.09.447719v2. 11 June 2021

eLife

Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1.
Zhao, X., Nedvetsky, P., Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Vion, A.C. ORCID: https://orcid.org/0000-0002-2788-2512, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Zühlke, K., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Klussmann, E. ORCID: https://orcid.org/0000-0003-4004-5003 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
eLife 8 : e46380. 3 October 2019

GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.
Hu, X. ORCID: https://orcid.org/0000-0002-0944-624X, Matsumoto, K., Jung, R.S., Weston, T.A., Heizer, P.J., He, C., Sandoval, N.P., Allan, C.M., Tu, Y., Vinters, H.V., Liau, L.M., Ellison, R.M., Morales, J.E., Baufeld, L.J., Bayley, N.A., He, L., Betsholtz, C., Beigneux, A.P., Nathanson, D.A., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Young, S.G. ORCID: https://orcid.org/0000-0001-7270-3176, Fong, L.G. ORCID: https://orcid.org/0000-0002-4465-5290 and Jiang, H. ORCID: https://orcid.org/0000-0002-2384-4826
eLife 8 : e47178. 6 June 2019

YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development.
Neto, F. ORCID: https://orcid.org/0000-0001-8382-2269, Klaus-Bergmann, A. ORCID: https://orcid.org/0000-0002-1164-3322, Ong, Y.T. ORCID: https://orcid.org/0000-0003-3407-2515, Alt, S. ORCID: https://orcid.org/0000-0003-1877-2968, Vion, A.C. ORCID: https://orcid.org/0000-0002-2788-2512, Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Carvalho, J.R., Hollfinger, I. ORCID: https://orcid.org/0000-0002-6233-8395, Bartels-Klein, E., Franco, C.A. ORCID: https://orcid.org/0000-0002-2861-3883, Potente, M. ORCID: https://orcid.org/0000-0002-5689-0036 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
eLife 7 : e31037. 5 February 2018

Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice.
Carmona, R. ORCID: https://orcid.org/0000-0002-9686-473X, Canete, A., Cano, E. ORCID: https://orcid.org/0000-0003-1091-8934, Ariza, L., Rojas, A. and Munoz-Chapuli, R. ORCID: https://orcid.org/0000-0001-6392-6802
eLife 5 : e16009. 19 September 2016

Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion.
Ubezio, B., Blanco, R.A., Geudens, I., Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Mathivet, T., Jones, M.L., Ragab, A., Bentley, K. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
eLife 5 : e12167. 13 April 2016

Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling.
Franco, C.A., Jones, M.L., Bernabeu, M.O., Vion, A.C. ORCID: https://orcid.org/0000-0002-2788-2512, Barbacena, P., Fan, J., Mathivet, T., Fonseca, C.G., Ragab, A., Yamaguchi, T.P., Coveney, P.V., Lang, R.A. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
eLife 5 : e07727. 4 February 2016

medRxiv

Plasma proteomics in acute heart failure: survival-associated protein signatures and 90-day trajectories.
Chitroceanu, Alexandra M., Fahjen, Pauline ORCID: https://orcid.org/0000-0002-5015-0643, Schulze, Daniel, Zach, Veronika, Alasfar, Lina, Ziehm, Matthias ORCID: https://orcid.org/0000-0001-7074-4054, Kirchner, Marieluise ORCID: https://orcid.org/0000-0002-7049-534X, Niquet, Sylvia, Dahmen, Jan-Niklas, Plappert, Carlos, Kretzler, Lucie, Kind, Andreas, Zurkan, Daniela, Pinto, Rafaela Maria, Reynolds, Edwardo, Trippel, Tobias D., Forslund, Sofia ORCID: https://orcid.org/0000-0003-4285-6993, Grittner, Ulrike, Mai, Knut, Gotthardt, Michael ORCID: https://orcid.org/0000-0003-1788-3172, Schiattarella, Gabriele G. ORCID: https://orcid.org/0000-0002-7582-7171, Kintscher, Ulrich, Ahmadi, Michael, Boldt, Leif-Hendrik, Buchmann, Nikolaus, Eckardt, Kai-Uwe, Endres, Matthias, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384, Hübner, Norbert ORCID: https://orcid.org/0000-0002-1218-6223, Kollmus-Heege, Jil, Landmesser, Ulf, Müller, Dominik N. ORCID: https://orcid.org/0000-0003-3650-5644, Nolte, Christian H., Piper, Sophie K., Rattan, Simrit, Rohrpasser-Napierkowski, Ira, Schönrath, Katharina, Schulz-Menger, Jeanette ORCID: https://orcid.org/0000-0003-3100-1092, Schweizerhof, Oliver, Pischon, Tobias ORCID: https://orcid.org/0000-0003-1568-767X, Pieske, Burkert ORCID: https://orcid.org/0000-0002-6466-5306, Weber, Joachim, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X and Edelmann, Frank
medRxiv : 2025.12.01.25341310. 3 December 2025