Helmholtz Gemeinschaft

Search
Browse
Statistics
Feeds

Browse by Research Team

Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: Date | Item Type | Source
Jump to: 2020 | 2019 | 2018 | 2017 | 2016

2020

Concepts and software package for efficient quality control in targeted metabolomics studies - MeTaQuaC.
Kuhring, M. and Eisenberger, A. and Schmidt, V. and Kränkel, N. and Leistner, D.M. and Kirwan, J. and Beule, D.
Analytical Chemistry 30 June 2020 (In Press)

Heart-specific immune responses in an animal model of autoimmune-related myocarditis mitigated by an immunoproteasome inhibitor and genetic ablation.
Bockstahler, M. and Fischer, A. and Goetzke, C.C. and Neumaier, H.L. and Sauter, M. and Kespohl, M. and Müller, A.M. and Meckes, C. and Salbach, C. and Schenk, M. and Heuser, A. and Landmesser, U. and Weiner, J. and Meder, B. and Lehmann, L. and Kratzer, A. and Klingel, K. and Katus, H.A. and Kaya, Z. and Beling, A.
Circulation 141 (23): 1885-1902. 9 June 2020

YAP and β-catenin co-operate to drive oncogenesis in basal breast cancer.
Quinn, H. and Koren, E. and Vogel, R. and Popp, O. and Mertins, P. and Messerschmidt, C. and Marangoni, E. and Fuchs, Y. and Birchmeier, W.
bioRxiv : 2020.06.05.115881. 6 June 2020

Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC.
Messerschmidt, C. and Obermayer, B. and Klinghammer, K. and Ochsenreither, S. and Treue, D. and Stenzinger, A. and Glimm, H. and Fröhling, S. and Kindler, T. and Brandts, C.H. and Schulze-Osthoff, K. and Weichert, W. and Tinhofer, I. and Klauschen, F. and Keilholz, U. and Beule, D. and Rieke, D.T.
International Journal of Cancer 29 May 2020 (In Press)

Progression-dependent altered metabolism in osteosarcoma resulting in different nutrient source dependencies.
Fritsche-Guenther, R. and Gloaguen, Y. and Kirchner, M. and Mertins, P. and Tunn, P.U. and Kirwan, J.A.
Cancers 12 (6): 1371. 27 May 2020

Enzymatic dissociation induces transcriptional and proteotype bias in brain cell populations.
Mattei, D. and Ivanov, A. and van Oostrum, M. and Pantelyushin, S. and Richetto, J. and Mueller, F. and Beffinger, M. M. and Schellhammer, L. and vom Berg, J. and Wollscheid, B. and Beule, D. and Paolicelli, R.C. and Meyer, U.
bioRxiv : 2020.05.14.095422. 16 May 2020

Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model.
Akpa, C.A. and Kleo, K. and Oker, E. and Tomaszewski, N. and Messerschmidt, C. and López, C. and Wagener, R. and Oehl-Huber, K. and Dettmer, K. and Schoeler, A. and Lenze, D. and Oefner, P.J. and Beule, D. and Siebert, R. and Capper, D. and Dimitrova, L. and Hummel, M.
BMC Cancer 20 (1): 427. 14 May 2020

Bulk and single-cell gene expression profiling of SARS-CoV-2 infected human cell lines identifies molecular targets for therapeutic intervention.
Wyler, E. and Mösbauer, K. and Franke, V. and Diag, A. and Gottula, L.T. and Arsie, R. and Klironomos, F. and Koppstein, D. and Ayoub, S. and Buccitelli, C. and Richter, A. and Legnini, I. and Ivanov, A. and Mari, T and Del Giudice, S. and Papies, J.P. and Müller, M.A. and Niemeyer, D. and Selbach, M. and Akalin, A. and Rajewsky, N. and Drosten, C. and Landthaler, M.
bioRxiv : 2020.05.05.079194. 5 May 2020

Investigating APOE, APP-Aβ metabolism genes and Alzheimer's disease GWAS hits in brain small vessel ischemic disease.
Blumenau, S. and Foddis, M. and Müller, S. and Holtgrewe, M. and Bentele, K. and Berchtold, D. and Beule, D. and Dirnagl, U. and Sassi, C.
Scientific Reports 10 (1): 7103. 28 April 2020

VarFish: comprehensive DNA variant analysis for diagnostics and research.
Holtgrewe, M. and Stolpe, O. and Nieminen, M. and Mundlos, S. and Knaus, A. and Kornak, U. and Seelow, D. and Segebrecht, L. and Spielmann, M. and Fischer-Zirnsak, B. and Boschann, F. and Scholl, U. and Ehmke, N. and Beule, D.
Nucleic Acids Research : gkaa241. 27 April 2020 (In Press)

Digestiflow: from BCL to FASTQ with ease.
Holtgrewe, M. and Messerschmidt, C. and Nieminen, M. and Beule, D.
Bioinformatics 36 (6): 1983-1985. 15 March 2020

Paroxysmal tonic upgaze: a heterogeneous clinical condition responsive to carbonic anhydrase inhibition.
Quade, A. and Thiel, A. and Kurth, I. and Holtgrewe, M. and Elbracht, M. and Beule, D. and Eggermann, K. and Scholl, U.I. and Häusler, M.
European Journal of Paediatric Neurology 25 : 181-186. March 2020

Support of a molecular tumour board by an evidence-based decision management system for precision oncology.
Lamping, M. and Benary, M. and Leyvraz, S. and Messerschmidt, C. and Blanc, E. and Kessler, T. and Schütte, M. and Lenze, D. and Jöhrens, K. and Burock, S. and Klinghammer, K. and Ochsenreither, S. and Sers, C. and Schäfer, R. and Tinhofer, I. and Beule, D. and Klauschen, F. and Yaspo, M.L. and Keilholz, U. and Rieke, D.T.
European Journal of Cancer 127 : 41-51. March 2020

Tracing tumorigenesis in a solid tumor model at single-cell resolution.
Praktiknjo, S.D. and Obermayer, B. and Zhu, Q. and Fang, L. and Liu, H. and Quinn, H. and Stoeckius, M. and Kocks, C. and Birchmeier, W. and Rajewsky, N.
Nature Communications 11 (1): 991. 20 February 2020

SCelVis: exploratory single cell data analysis on the desktop and in the cloud.
Obermayer, B. and Holtgrewe, M. and Nieminen, M. and Messerschmidt, C. and Beule, D.
PeerJ 8 : e8607. 19 February 2020

Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model.
Thole, T.M. and Toedling, J. and Sprüssel, A. and Pfeil, S. and Savelyeva, L. and Capper, D. and Messerschmidt, C. and Beule, D. and Groeneveld-Krentz, S. and Eckert, C. and Gambara, G. and Henssen, A.G. and Finkler, S. and Schulte, J.H. and Sieber, A. and Bluethgen, N. and Regenbrecht, C.R.A. and Künkele, A. and Lodrini, M. and Eggert, A. and Deubzer, H.E.
International Journal of Cancer 146 (4): 1031-1041. 15 February 2020

The architecture of protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit.
Kraushar, M.L. and Krupp, F. and Turko, P. and Ambrozkiewicz, M.C. and Sprink, T. and Imami, K. and Vieira-Vieira, C.H. and Schaub, T. and Harnett, D. and Münster-Wandowski, A. and Bürger, J. and Zinnall, U. and Borisova, E. and Yamamoto, H. and Rasin, M.R. and Beule, D. and Landthaler, M. and Mielke, T. and Tarabykin, V. and Vida, I. and Selbach, M. and Spahn, C.M.T.
bioRxiv : 2020.02.08.939488. 10 February 2020

An exploratory investigation of brain collateral circulation plasticity after cerebral ischemia in two experimental C57BL/6 mouse models.
Foddis, M. and Winek, K. and Bentele, K. and Mueller, S. and Blumenau, S. and Reichhart N, N. and Crespo-Garcia, S. and Harnett, D. and Ivanov, A. and Meisel, A. and Joussen, A. and Strauss, O. and Beule, D. and Dirnagl, U. and Sassi, C.
Journal of Cerebral Blood Flow and Metabolism 40 (2): 276-287. 1 February 2020

Generation and characterization of a mitotane-resistant adrenocortical cell line.
Seidel, E. and Walenda, G. and Messerschmidt, C. and Obermayer, B. and Peitzsch, M. and Wallace, P. and Bahethi, R. and Yoo, T. and Choi, M. and Schrade, P. and Bachmann, S. and Liebisch, G. and Eisenhofer, G. and Beule, D. and Scholl, U.
Endocrine Connections 9 (2): 122-134. February 2020

VarFish - Collaborative and comprehensive variant analysis for diagnosis and research.
Holtgrewe, M. and Stolpe, O. and Nieminen, M. and Mundlos, S. and Knaus, A. and Kornak, U. and Seelow, D. and Segebrecht, L. and Spielmann, M. and Fischer-Zirnsak, B. and Boschann, F. and Scholl, U. and Ehmke, N. and Beule, D.
bioRxiv : 2020.01.27.921965. 31 January 2020

A census of cell types and paracrine interactions in colorectal cancer.
Uhlitz, F. and Bischoff, P. and Sieber, A. and Obermayer, B. and Blanc, E. and Lüthen, M. and Sawitzki, B. and Kamphues, C. and Beule, D. and Sers, C. and Horst, D. and Blüthgen, N. and Morkel, M.
bioRxiv : 2020.01.10.901579. 11 January 2020

Concepts and software package for efficient quality control in targeted metabolomics studies – MeTaQuaC.
Kuhring, M. and Eisenberger, A. and Schmidt, V. and Kränkel, N. and Leistner, D.M. and Kirwan, J. and Beule, D.
bioRxiv : 2020.01.10.901710. 11 January 2020

Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Koche, R.P. and Rodriguez-Fos, E. and Helmsauer, K. and Burkert, M. and MacArthur, I.C. and Maag, J. and Chamorro, R. and Munoz-Perez, N. and Puiggròs, M. and Dorado Garcia, H. and Bei, Y. and Röefzaad, C. and Bardinet, V. and Szymansky, A. and Winkler, A. and Thole, T. and Timme, N. and Kasack, K. and Fuchs, S. and Klironomos, F. and Thiessen, N. and Blanc, E. and Schmelz, K. and Künkele, A. and Hundsdörfer, P. and Rosswog, C. and Theissen, J. and Beule, D. and Deubzer, H. and Sauer, S. and Toedling, J. and Fischer, M. and Hertwig, F. and Schwarz, R.F. and Eggert, A. and Torrents, D. and Schulte, J.H. and Henssen, A.G.
Nature Genetics 52 (1): 29-34. January 2020

2019

Modified protocol of harvesting, extraction, and normalization approaches for gas chromatography mass spectrometry-based metabolomics analysis of adherent cells grown under high fetal calf serum conditions.
Fritsche-Guenther, R. and Bauer, A. and Gloaguen, Y. and Lorenz, M. and Kirwan, J.A.
Metabolites 10 (1): 2. 18 December 2019

let-7 microRNAs regulate microglial function and suppress glioma growth through Toll-like receptor 7.
Buonfiglioli, A. and Efe, I.E. and Guneykaya, D. and Ivanov, A. and Huang, Y. and Orlowski, E. and Krüger, C. and Deisz, R.A. and Markovic, D. and Flüh, C. and Newman, A.G. and Schneider, U.C. and Beule, D. and Wolf, S.A. and Dzaye, O. and Gutmann, D.H. and Semtner, M. and Kettenmann, H. and Lehnardt, S.
Cell Reports 29 (11): 3460-3471. 10 December 2019

Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3.
Kühnisch, J. and Herbst, C. and Al-Wakeel-Marquard, N. and Dartsch, J. and Holtgrewe, M. and Baban, A. and Mearini, G. and Hardt, J. and Kolokotronis, K. and Gerull, B. and Carrier, L. and Beule, D. and Schubert, S. and Messroghli, D. and Degener, F. and Berger, F. and Klaassen, S.
Clinical Genetics 96 (6): 549-559. December 2019

Identification and ranking of recurrent neo-epitopes in cancer.
Blanc, E. and Holtgrewe, M. and Dhamodaran, A. and Messerschmidt, C. and Willimsky, G. and Blankenstein, T. and Beule, D.
BMC Medical Genomics 12 : 171. 27 November 2019

SigsPack, a package for cancer mutational signatures.
Schumann, F. and Blanc, E. and Messerschmidt, C. and Blankenstein, T. and Busse, A. and Beule, D.
BMC Bioinformatics 20 (1): 450. 2 September 2019

WiPP: workflow for improved peak picking for gas chromatography-mass spectrometry (GC-MS) data.
Borgsmüller, N. and Gloaguen, Y. and Opialla, T. and Blanc, E. and Sicard, E. and Royer, A.L. and Le Bizec, B. and Durand, S. and Migné, C. and Pétéra, M. and Pujos-Guillot, E. and Giacomoni, F. and Guitton, Y. and Beule, D. and Kirwan, J.
Metabolites 9 (9): 171. 21 August 2019

AltamISA: a Python API for ISA-Tab files.
Kuhring, M. and Nieminen, M. and Kirwan, J. and Beule, D. and Holtgrewe, M.
Journal of Open Source Software 4 (40): 1610. 20 August 2019

SCelVis: Powerful explorative single cell data analysis on the desktop and in the cloud.
Obermayer, B. and Holtgrewe, M. and Nieminen, M. and Messerschmidt, C. and Beule, D.
bioRxiv : 713008. 24 July 2019

WiPP: workflow for improved peak picking for gas chromatography-mass spectrometry (GC-MS) data.
Borgsmüller, N. and Gloaguen, Y. and Opialla, T. and Blanc, E. and Sicard, E. and Royer, A.L. and Le Bizec, B. and Durand, S. and Migné, C. and Pétéra, M. and Pujos-Guillot, E. and Giacomoni, F. and Guitton, Y. and Beule, D. and Kirwan, J.
bioRxiv : 713925. 24 July 2019

Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC.
Messerschmidt, C. and Obermayer, B. and Klinghammer, K. and Ochsenreither, S. and Treue, D. and Stenzinger, A. and Glimm, H. and Fröhling, S. and Kindler, T. and Brandts, C.H. and Schulze-Osthoff, K. and Weichert, W. and Tinhofer, I. and Klauschen, F. and Keilholz, U. and Beule, D. and Rieke, D.T.
bioRxiv : 586396. 28 March 2019

The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A. and Babila, J.T. and Wiglenda, T. and Diez, L. and Jacob, M. and Nietfeld, W. and Huska, M.R. and Haenig, C. and Groenke, N. and Buntru, A. and Blanc, E. and Meier, J.C. and Vannoni, E. and Erck, C. and Friedrich, B. and Martens, H. and Neuendorf, N. and Schnoegl, S. and Wolfer, D.P. and Loos, M. and Beule, D. and Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 26 (1): 109-120. 17 January 2019

2018

Multisite de novo mutations in human offspring after paternal exposure to ionizing radiation.
Holtgrewe, M. and Knaus, A. and Hildebrand, G. and Pantel, J.T. and de los Santos, M.R. and Neveling, K. and Goldmann, J. and Schubach, M. and Jäger, M. and Coutelier, M. and Mundlos, S. and Beule, D. and Sperling, K. and Krawitz, P.M.
Scientific Reports 8 (1): 14611. 2 October 2018

Emergence of robust nucleosome patterns from an interplay of positioning mechanisms.
Nuebler, J. and Wolff, M. and Obermayer, B. and Mobius, W. and Gerland, U.
bioRxiv : 431445. 1 October 2018

Parasitic nematodes exert antimicrobial activity and benefit from microbiota-driven support for host immune regulation.
Rausch, S. and Midha, A. and Kuhring, M. and Affinass, N. and Radonic, A. and Kühl, A.A. and Bleich, A. and Renard, B.Y. and Hartmann, S.
Frontiers in Immunology 9 : 2282. October 2018

Transcriptional and translational differences of microglia from male and female brains.
Guneykaya, D. and Ivanov, A. and Perez Hernandez, D. and Haage, V. and Wojtas, B. and Meyer, N. and Maricos, M. and Jordan, P. and Buonfiglioli, A. and Gielniewski, B. and Ochocka, N. and Cömert, C. and Friedrich, C. and Suarez Artiles, L. and Kaminska, B. and Mertins, P. and Beule, D. and Kettenmann, H. and Wolf, S.A.
Cell Reports 24 (10): 2773-2783. 4 September 2018

Silent witness: dual-species transcriptomics reveals epithelial immunological quiescence to helminth larval encounter and fostered larval development.
Ebner, F. and Kuhring, M. and Radonic, A. and Midha, A. and Renard, B.Y. and Hartmann, S.
Frontiers in Immunology 9 : 1868. 15 August 2018

Identification and ranking of recurrent neo-epitopes in cancer.
Blanc, E. and Holtgrewe, M. and Dhamodaran, A. and Messerschmidt, C. and Willimsky, G. and Blankenstein, T. and Beule, D.
bioRxiv : 389437. 10 August 2018

MetExplore: collaborative edition and exploration of metabolic networks.
Cottret, L. and Frainay, C. and Chazalviel, M. and Cabanettes, F. and Gloaguen, Y. and Camenen, E. and Merlet, B. and Heux, S. and Portais, J.C. and Poupin, N. and Vinson, F. and Jourdan, F.
Nucleic Acids Research 46 (W1): W495-W502. 2 July 2018

Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure.
Salatzki, J. and Foryst-Ludwig, A. and Bentele, K. and Blumrich, A. and Smeir, E. and Ban, Z. and Brix, S. and Grune, J. and Beyhoff, N. and Klopfleisch, R. and Dunst, S. and Surma, M.A. and Klose, C. and Rothe, M. and Heinzel, F.R. and Krannich, A. and Kershaw, E.E. and Beule, D. and Schulze, P.C. and Marx, N. and Kintscher, U.
PLoS Genetics 14 (1): e1007171. 10 January 2018

2017

HLA-MA: simple yet powerful matching of samples using HLA typing results.
Messerschmidt, C. and Holtgrewe, M. and Beule, D.
Bioinformatics 33 (14): 2241-2242. 15 July 2017

Drug resistance mechanisms in colorectal cancer dissected with cell type-specific dynamic logic models.
Eduati, F. and Doldan-Martelli, V. and Klinger, B. and Cokelaer, T. and Sieber, A. and Kogera, F. and Dorel, M. and Garnett, M.J. and Bluethgen, N. and Saez-Rodriguez, J.
Cancer Research 77 (12): 3364-3375. 15 June 2017

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.
Mattei, D. and Ivanov, A. and Ferrai, C. and Jordan, P. and Guneykaya, D. and Buonfiglioli, A. and Schaafsma, W. and Przanowski, P. and Deuther-Conrad, W. and Brust, P. and Hesse, S. and Patt, M. and Sabri, O. and Ross, T.L. and Eggen, B.J.L. and Boddeke, E.W.G.M. and Kaminska, B. and Beule, D. and Pombo, A. and Kettenmann, H. and Wolf, S.A.
Translational Psychiatry 7 (5): e1120. 9 May 2017

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T. and Friese, C. and Arina, A. and Idel, C. and Briesemeister, D. and Rothe, M. and Ivanov, A. and Szymborska, A. and Patone, G. and Kunz, S. and Sommermeyer, D. and Engels, B. and Leisegang, M. and Textor, A. and Fehling, H.J. and Fruttiger, M. and Lohoff, M. and Herrmann, A. and Yu, H. and Weichselbaum, R. and Uckert, W. and Hübner, N. and Gerhardt, H. and Beule, D. and Schreiber, H. and Blankenstein, T.
Nature 545 (7652): 98-102. 4 May 2017

DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.
Mamlouk, S. and Childs, L.H. and Aust, D. and Heim, D. and Melching, F. and Oliveira, C. and Wolf, T. and Durek, P. and Schumacher, D. and Blaeker, H. and von Winterfeld, M. and Gastl, B. and Moehr, K. and Menne, A. and Zeugner, S. and Redmer, T. and Lenze, D. and Tierling, S. and Moebs, M. and Weichert, W. and Folprecht, G. and Blanc, E. and Beule, D. and Schaefer, R. and Morkel, M. and Klauschen, F. and Leser, U. and Sers, C.
Nature Communications 8 : 14093. 25 January 2017

2016

HLA-MA: Simple yet powerful matching of samples using HLA typing results.
Messerschmidt, C. and Holtgrewe, M. and Beule, D.
bioRxiv : 066548. 24 August 2016

This list was generated on Tue Jul 7 02:21:48 2020 CEST.
Open Access
MDC Library