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Article

Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry.
Ben Hamza, A. and Welters, C. and Stadler, S. and Brüggemann, M. and Dietze, K. and Brauns, O. and Brümmendorf, T.H. and Winkler, T.H. and Bullinger, L. and Blankenstein, T. and Rosenberger, L. and Leisegang, M. and Kammertöns, T. and Herr, W. and Moosmann, A. and Strobel, J. and Hackstein, H. and Dornmair, K. and Beier, F. and Hansmann, L.
Blood 143 (14): 1365-1378. 4 April 2024

Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022.
Baumgartner, F. and Baer, C. and Bamopoulos, S.A. and Ayoub, E. and Truger, M. and Meggendorfer, M. and Lenk, M. and Hoermann, G. and Hutter, S. and Müller, H. and Walter, W. and Mueller, M.L. and Nadarajah, Ni. and Blombery, P. and Keller, U. and Kern, W. and Haferlach, C. and Haferlach, T.
Blood 143 (12): 1139-1156. 21 March 2024

Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz.
Uehata, T. and Yamada, S. and Ori, D. and Vandenbon, A. and Giladi, A. and Jelinski, A. and Murakawa, Y. and Watanabe, H. and Takeuchi, K. and Toratani, K. and Mino, T. and Kiryu, H. and Standley, D.M. and Tsujimura, T. and Ikawa, T. and Kondoh, G. and Landthaler, M. and Kawamoto, H. and Rodewald, H.R. and Amit, I. and Yamamoto, R. and Miyazaki, M. and Takeuchi, O.
Blood 143 (3): 243-257. 18 January 2024

Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
Jiang, Q. and Stachelscheid, J. and Bloehdorn, J. and Pacholewska, A. and Aszyk, C.M. and Grotenhuijs, F. and Müller, T.A. and Onder, O. and Wagle, P. and Herling, C.D. and Kleppe, M. and Wang, Z. and Coombes, K.R. and Robrecht, S. and Dalvi, P.S. and Plosnita, B. and Mayer, P. and Abruzzo, L.V. and Altmüller, J. and Gathof, B.S. and Persigehl, T. and Fischer, K. and Jebaraj, B.M.C. and Rienhoff, H.Y. and Ecker, R.C. and Zhao, Y. and Bruns, C.J. and Stilgenbauer, S. and Elenitoba-Johnson, K.S.J. and Hallek, M. and Schweiger, M.R. and Odenthal, M. and Vasyutina, E. and Herling, M.
Blood 142 (1): 44-61. 6 July 2023

Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development.
Mueller-Calleja, N. and Grunz, K. and Nguyen, T.S. and Posma, J. and Pedrosa, D. and Meineck, M. and Hollerbach, A. and Braun, J. and Muth, S. and Schild, H. and Saar, K. and Hübner, N. and Krishnaswamy, S. and Royce, J. and Teyton, L. and Lemmermann, N.A. and Weinmann-Menke, J. and Lackner, K.J. and Ruf, W.
Blood 143 (12): 1167-1180. 21 March 2023

Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends, C.M. and Liman, T.G. and Strzelecka, P.M. and Kufner, A. and Löwe, P. and Huo, S. and Stein, C.M. and Piper, S.K. and Tilgner, M. and Sperber, P.S. and Dimitriou, S. and Heuschmann, P. and Hablesreiter, R. and Harms, C. and Bullinger, L. and Weber, J.E. and Endres, M. and Damm, F.
Blood 141 (7): 787-799. 16 February 2023

Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies.
Thomalla, D. and Beckmann, L. and Grimm, C. and Oliverio, M. and Meder, L. and Herling, C.D. and Nieper, P. and Feldmann, T. and Merkel, O. and Lorsy, E. and da Palma Guerreiro, A. and von Jan, J. and Kisis, I. and Wasserburger, E. and Claasen, J. and Faitschuk-Meyer, E. and Altmüller, J. and Nürnberg, P. and Yang, T.P. and Lienhard, M. and Herwig, R. and Kreuzer, K.A. and Pallasch, C.P. and Buettner, R. and Schäfer, S.C. and Hartley, J. and Abken, H. and Peifer, M. and Kashkar, H. and Knittel, G. and Eichhorst, B. and Ullrich, R.T. and Herling, M. and Reinhardt, H.C. and Hallek, M. and Schweiger, M.R. and Frenzel, L.P.
Blood 140 (20): 2113-2126. 17 November 2022

Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
Ludwig, L.S. and Lareau, C.A. and Bao, E.L. and Liu, N. and Utsugisawa, T. and Tseng, A.M. and Myers, S.A. and Verboon, J.M. and Ulirsch, J.C. and Luo, W. and Muus, C. and Fiorini, C. and Olive, M.E. and Vockley, C.M. and Munschauer, M. and Hunter, A. and Ogura, H. and Yamamoto, T. and Inada, H. and Nakagawa, S. and Ozono, S. and Subramanian, V. and Chiarle, R. and Glader, B. and Carr, S.A. and Aryee, M.J. and Kundaje, A. and Orkin, S. and Regev, A. and McCavit, T. and Kanno, H. and Sankaran, V.G.
Blood 139 (16): 2534-2546. 21 April 2022

PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder, T.M. and Schwarzer, A. and Jayavelu, A.K. and Hsu, C.J. and Kirkpatrick, J. and Döhner, K. and Perner, F. and Eifert, T. and Huber, N. and Arreba-Tutusaus, P. and Dolnik, A. and Assi, S.A. and Nafria, M. and Jiang, L. and Dai, Y.T. and Chen, Z. and Chen, S.J. and Kellaway, S.G. and Ptasinska, A. and Ng, E.S. and Stanley, E.G. and Elefanty, A.G. and Buschbeck, M. and Bierhoff, H. and Brodt, S. and Matziolis, G. and Fischer, K.D. and Hochhaus, A. and Chen, C.W. and Heidenreich, O. and Mann, M. and Lane, S.W. and Bullinger, L. and Ori, A. and von Eyss, B. and Bonifer, C. and Heidel, F.
Blood 139 (7): 1080-1097. 17 February 2022

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke, A.C. and Doebele, C. and Zindel, A. and Lee, K.S. and Rieke, S.A. and Ceribelli, M. and Comoglio, F. and Phelan, J.D. and Wang, J.Q. and Pikman, Y. and Jahn, D. and Häupl, B. and Schneider, C. and Scheich, S. and Tosto, F.A. and Bohnenberger, H. and Stauder, P. and Schnütgen, F. and Slabicki, M. and Coulibaly, Z.A. and Wolf, S. and Bojarczuk, K. and Chapuy, B. and Brandts, C.H. and Stroebel, P. and Lewis, C.A. and Engelke, M. and Xu, X. and Kim, H. and Dang, T.H. and Schmitz, R. and Hodson, D.J. and Stegmaier, K. and Urlaub, H. and Serve, H. and Schmitt, C.A. and Kreuz, F. and Knittel, G. and Rabinowitz, J.D. and Reinhardt, H.C. and Vander Heiden, M.G. and Thomas, C. and Staudt, L.M. and Zenz, T. and Oellerich, T.
Blood 139 (4): 538-553. 27 January 2022

Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.
Schmalbrock, L.K. and Dolnik, A. and Cocciardi, S. and Sträng, E. and Theis, F. and Jahn, N. and Panina, E. and Blätte, T.J. and Herzig, J.K. and Skambraks, S. and Rücker, F.G. and Gaidzik, V.I. and Paschka, P. and Fiedler, W. and Salih, H.R. and Wulf, G.G. and Schroeder, T. and Lübbert, M. and Schlenk, R.F. and Thol, F. and Heuser, M. and Larson, R.A. and Ganser, A. and Stunnenberg, H.G. and Minucci, S. and Stone, R.M. and Bloomfield, C.D. and Döhner, H. and Döhner, K. and Bullinger, L.
Blood 137 (22): 3093-3104. 3 June 2021

Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
Reimann, M. and Schrezenmeier, J.F. and Richter-Pechanska, P. and Dolnik, A. and Hick, T.P. and Schleich, K. and Cai, X. and Fan, D.N.Y. and Lohneis, P. and Masswig, S. and Denker, S. and Busse, A. and Knittel, G. and Flümann, R. and Childs, D. and Childs, L. and Gätjens-Sanchez, A.M. and Bullinger, L. and Rosenwald, A. and Reinhardt, H.C. and Schmitt, C.A.
Blood 137 (20): 2785-2899. 20 May 2021

A randomized phase 3 trial of autologous vs allogeneic transplantation as part of first-line therapy in poor-risk peripheral T-NHL.
Schmitz, N. and Truemper, L.H. and Bouabdallah, K. and Ziepert, M. and Leclerc, M. and Cartron, G. and Jaccard, A. and Reimer, P. and Wagner-Drouet, E.M. and Wilhelm, M. and Sanhes, L. and Lamy, T. and de Leval, L. and Rosenwald, A. and Roussel, M. and Kroschinsky, F.P. and Lindemann, W.W. and Dreger, P. and Viardot, A. and Milpied, N.J. and Gisselbrecht, C. and Wulf, G.G. and Gyan, E. and Gaulard, P. and Bay, J.O. and Glass, B. and Poeschel, V. and Damaj, G. and Sibon, D. and Delmer, A.J. and Bilger, K. and Banos, A. and Haenel, M. and Dreyling, M. and Metzner, B. and Keller, U. and Braulke, F. and Friedrichs, B. and Nickelsen, M. and Altmann, B. and Tournilhac, O.
Blood 137 (19): 2646-2656. 13 May 2021

Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial.
Kapp-Schwoerer, S. and Weber, D. and Corbacioglu, A. and Gaidzik, V.I. and Paschka, P. and Krönke, J. and Theis, F. and Rücker, F.G. and Teleanu, M.V. and Panina, E. and Jahn, N. and Herzig, J. and Kubanek, L. and Schrade, A. and Göhring, G. and Fiedler, W. and Kindler, T and Schroeder, T. and Mayer, K.T. and Lübbert, M. and Wattad, M. and Götze, K.S. and Horst, H.A. and Koller, E. and Wulf, G. and Schleicher, J. and Bentz, M. and Krauter, J. and Bullinger, L. and Krzykalla, J. and Benner, A. and Schlenk, R.F. and Thol, F. and Heuser, M. and Ganser, A. and Döhner, H and Döhner, K.
Blood 136 (26): 3041-3050. 24 December 2020

Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1.
Reinke, S. and Bröckelmann, P.J. and Iaccarino, I. and Garcia-Marquez, M. and Borchmann, S. and Jochims, F. and Kotrova, M. and Pal, K. and Brüggemann, M. and Hartmann, E. and Sasse, S. and Kobe, C. and Mathas, S. and Soekler, M. and Keller, U. and Bormann, M. and Zimmermann, A. and Richter, J. and Fuchs, M. and von Tresckow, B. and Borchmann, P. and Schlößer, H. and von Bergwelt-Baildon, M. and Rosenwald, A. and Engert, A. and Klapper, W.
Blood 136 (25): 2851-2863. 17 December 2020

Noncanonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling.
Oberbeck, S. and Schrader, A. and Warner, K. and Jungherz, D. and Crispatzu, G. and von Jan, J. and Chmielewski, M. and Ianevski, A. and Diebner, H.H. and Mayer, P. and Kondo Ados, A. and Wahnschaffe, L. and Braun, T. and Müller, T.A. and Wagle, P. and Bouska, A. and Neumann, T. and Pützer, S. and Varghese, L. and Pflug, N. and Thelen, M. and Makalowski, J. and Riet, N. and Göx, H.J.M and Rappl, G. and Altmüller, J. and Kotrová, M. and Persigehl, T. and Hopfinger, G. and Hansmann, M.L. and Schlößer, H. and Stilgenbauer, S. and Dürig, J. and Mougiakakos, D. and von Bergwelt-Baildon, M. and Roeder, I. and Hartmann, S. and Hallek, M. and Moriggl, R. and Brüggemann, M. and Aittokallio, T. and Iqbal, J. and Newrzela, S. and Abken, H. and Herling, M.
Blood 136 (24): 2786-2802. 10 December 2020

Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells.
Raffel, S. and Klimmeck, D. and Falcone, M. and Demir, A. and Pouya, A. and Zeisberger, P. and Lutz, C. and Tinelli, M. and Bischel, O. and Bullinger, L. and Thiede, C. and Flörcken, A. and Westermann, J. and Ehninger, G. and Ho, A.D. and Müller-Tidow, C. and Gu, Z. and Herrmann, C. and Krijgsveld, J. and Trumpp, A. and Hansson, J.
Blood 136 (13): 1507-1519. 24 September 2020

Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
Yusuf, R.Z. and Saez, B. and Sharda, A. and van Gastel, N. and Yu, V.W.C. and Baryawno, N. and Scadden, E.W. and Acharya, S. and Chattophadhyay, S. and Huang, C. and Viswanathan, V. and S'aulis, D. and Cobert, J. and Sykes, D.B. and Keibler, M.A. and Das, S. and Hutchinson, J.N. and Churchill, M. and Mukherjee, S. and Lee, D. and Mercier, F. and Doench, J. and Bullinger, L. and Logan, D.J. and Schreiber, S. and Stephanopoulos, G. and Rizzo, W.B. and Scadden, D.T.
Blood 136 (11): 1303-1316. 10 September 2020

Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta.
Yvernogeau, L. and Klaus, A. and Maas, J. and Morin-Poulard, I. and Weijts, B. and Schulte-Merker, S. and Berezikov, E. and Junker, J.P. and Robin, C.
Blood 136 (7): 831-844. 13 August 2020

Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax.
Tausch, E. and Schneider, C. and Robrecht, S. and Zhang, C. and Dolnik, A. and Bloehdorn, J. and Bahlo, J. and Al-Sawaf, O. and Ritgen, M. and Fink, A.M. and Eichhorst, B. and Kreuzer, K.A. and Tandon, M. and Humphrey, K. and Jiang, Y. and Schary, W. and Bullinger, L. and Mertens, D. and Lurà, M.P. and Kneba, M. and Döhner, H. and Fischer, K. and Hallek, M. and Stilgenbauer, S.
Blood 135 (26): 2402-2412. 25 June 2020

Measurable residual disease monitoring in acute myeloid leukemia with t(8;21)(q22;q22.1): results from the AML Study Group.
Rücker, F.G. and Agrawal, M. and Corbacioglu, A. and Weber, D. and Kapp-Schwoerer, S. and Gaidzik, V.I. and Jahn, N. and Schroeder, T. and Wattad, M. and Lübbert, M. and Koller, E. and Kindler, T. and Götze, K. and Ringhoffer, M. and Westermann, J. and Fiedler, W. and Horst, H.A. and Greil, R. and Schroers, R. and Mayer, K. and Heinicke, T. and Krauter, J. and Schlenk, R.F. and Thol, F. and Heuser, M. and Ganser, A. and Bullinger, L. and Paschka, P. and Döhner, H. and Döhner, K.
Blood 134 (19): 1608-1618. 7 November 2019

IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia.
Scheffold, A. and Jebaraj, B.M.C. and Tausch, E. and Bloehdorn, J. and Ghia, P. and Yahiaoui, A. and Dolnik, A. and Blätte, T.J. and Bullinger, L. and Dheenadayalan, R.P. and Li, L. and Schneider, C. and Chen, S.S. and Chiorazzi, N. and Dietrich, S. and Seiffert, M. and Tannheimer, S. and Döhner, H. and Mertens, D. and Stilgenbauer, S.
Blood 134 (6): 534-547. 8 August 2019

Chronic CD30-signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells.
Sperling, S.A. and Fiedler, P. and Lechner, M. and Pollithy, A. and Ehrenberg, S. and Schiefer, A.I. and Kenner, L. and Feuchtinger, A. and Kühn, R. and Swinerd, G. and Schmidt-Supprian, M. and Strobl, L.J. and Zimber-Strobl, U.
Blood 133 (24): 2597-2609. 13 June 2019

NCAM1 (CD56) promotes leukemogenesis and confers drug resistance in AML.
Sasca, D. and Szybinski, J. and Schüler, A. and Shah, V. and Heidelberger, J. and Haehnel, P.S. and Dolnik, A. and Kriege, O. and Fehr, E.M. and Gebhardt, W.H. and Reid, G. and Scholl, C. and Theobald, M. and Bullinger, L. and Beli, P. and Kindler, T.
Blood 133 (21): 2305-2319. 23 May 2019

Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations.
Jutzi, J.S. and Basu, T. and Pellmann, M. and Kaiser, S. and Steinemann, D. and Sanders, M.A. and Hinai, A.S.A. and Zeilemaker, A. and Bojtine Kovacs, S. and Koellerer, C. and Ostendorp, J. and Aumann, K. and Wang, W. and Raffoux, E. and Cassinat, B. and Bullinger, L. and Schlegelberger, B. and Valk, P.J.M. and Pahl, H.L.
Blood 133 (16): 1766-1777. 18 April 2019

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L. and Kärgel, E. and Franke, V. and McShane, E. and Schulz-Beiss, K.W. and Patone, G. and Schleussner, N. and Kolesnichenko, M. and Hübner, N. and Daumke, O. and Selbach, M. and Akalin, A. and Mathas, S. and Scheidereit, C.
Blood 133 (13): 1489-1494. 28 March 2019

Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients.
Christen, F. and Hoyer, K. and Yoshida, K. and Hou, H.A. and Waldhueter, N. and Heuser, M. and Hills, R.K. and Chan, W. and Hablesreiter, R. and Blau, O. and Ochi, Y. and Klement, P. and Chou, W.C. and Blau, I.W. and Tang, J.L. and Zemojtel, T. and Shiraishi, Y. and Shiozawa, Y. and Thol, F. and Ganser, A. and Löwenberg, B. and Linch, D.C. and Bullinger, L. and Valk, P.J.M. and Tien, H.F. and Gale, R.E. and Ogawa, S. and Damm, F.
Blood 133 (10): 1140-1151. 7 March 2019

The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma.
Wagener, R. and Seufert, J. and Raimondi, F. and Bens, S. and Kleinheinz, K. and Nagel, I. and Altmüller, J. and Thiele, H. and Hübschmann, D. and Kohler, C.W. and Nürnberg, P. and Au-Yeung, R. and Burkhardt, B. and Horn, H. and Leoncini, L. and Jaffe, E.S. and Ott, G. and Rymkiewicz, G. and Schlesner, M. and Russell, R.B. and Klapper, W. and Siebert, R.
Blood 133 (9): 962-966. 28 February 2019

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.
Jacquelin, S. and Straube, J. and Cooper, L. and Vu, T. and Song, A. and Bywater, M. and Baxter, E. and Heidecker, M. and Wackrow, B. and Porter, A. and Ling, V. and Green, J. and Austin, R. and Kazakoff, S. and Waddell, N. and Hesson, L.B. and Pimanda, J.E. and Stegelmann, F. and Bullinger, L. and Döhner, K. and Rampal, R.K. and Heckl, D. and Hill, G.R. and Lane, S.W.
Blood 132 (26): 2707-2721. 27 December 2018

Nrf2 regulates CD4(+) T cell-induced acute graft-versus-host disease in mice.
Tsai, J.J. and Velardi, E. and Shono, Y. and Argyropoulos, K.V. and Holland, A.M. and Smith, O.M. and Yim, N.L. and Rao, U.K. and Kreines, F.M. and Lieberman, S.R. and Young, L.F. and Lazrak, A. and Youssef, S. and Fu, Y.Y. and Liu, C. and Lezcano, C. and Murphy, G.F. and Na, I.K. and Jenq, R.R. and Hanash, A.M. and Dudakov, J.A. and van den Brink, M.R.M.
Blood 132 (26): 2763-2774. 27 December 2018

Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells.
Kabrani, E. and Chu, V.T. and Tasouri, E. and Sommermann, T. and Baßler, K. and Ulas, T. and Zenz, T. and Bullinger, L. and Schultze, J.L. and Rajewsky, K. and Sander, S.
Blood 132 (25): 2670-2683. 20 December 2018

IG-MYC(+) neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas.
Wagener, R. and López, C. and Kleinheinz, K. and Bausinger, J. and Aukema, S.M. and Nagel, I. and Toprak, U.H. and Seufert, J. and Altmüller, J. and Thiele, H. and Schneider, C. and Kolarova, J. and Park, J. and Hübschmann, D. and Murga Penas, E.M. and Drexler, H.G. and Attarbaschi, A. and Hovland, R. and Kjeldsen, E. and Kneba, M. and Kontny, U. and de Leval, L. and Nürnberg, P. and Oschlies, I. and Oscier, D. and Schlegelberger, B. and Stilgenbauer, S. and Wössmann, W. and Schlesner, M. and Burkhardt, B. and Klapper, W. and Jaffe, E.S. and Küppers, R. and Siebert, R.
Blood 132 (21): 2280-2285. 22 November 2018

Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML.
Thol, F. and Gabdoulline, R. and Liebich, A. and Klement, P. and Schiller, J. and Kandziora, C. and Hambach, L. and Stadler, M. and Koenecke, C. and Flintrop, M. and Pankratz, M. and Wichmann, M. and Neziri, B. and Büttner, K. and Heida, B. and Klesse, S. and Chaturvedi, A. and Kloos, A. and Göhring, G. and Schlegelberger, B. and Gaidzik, V.I. and Bullinger, L. and Fiedler, W. and Heim, A. and Hamwi, I. and Eder, M. and Krauter, J. and Schlenk, R.F. and Paschka, P. and Döhner, K. and Döhner, H. and Ganser, A. and Heuser, M.
Blood 132 (16): 1703-1713. 18 October 2018

PPM1D truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells.
Kahn, J.D. and Miller, P.G. and Silver, A.J. and Sellar, R.S. and Bhatt, S. and Gibson, C. and McConkey, M. and Adams, D. and Mar, B. and Mertins, P. and Fereshetian, S. and Krug, K. and Zhu, H. and Letai, A. and Carr, S.A. and Doench, J. and Jaiswal, S. and Ebert, B.L.
Blood 132 (11): 1095-1105. 13 September 2018

Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice.
Hoser, D. and Schön, C. and Loddenkemper, C. and Lohneis, P. and Kühl, A.A. and Sommermann, T. and Blankenstein, T. and Willimsky, G.
Blood 132 (9): 924-934. 30 August 2018

Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.
Maifrede, S. and Nieborowska-Skorska, M. and Sullivan-Reed, K. and Dasgupta, Y. and Podszywalow-Bartnicka, P. and Le, B.V. and Solecka, M. and Lian, Z. and Belyaeva, E.A. and Nersesyan, A. and Machnicki, M.M. and Toma, M. and Chatain, N. and Rydzanicz, M. and Zhao, H. and Jelinek, J. and Piwocka, K. and Sliwinski, T. and Stoklosa, T. and Ploski, R. and Fischer, T. and Sykes, S.M. and Koschmieder, S. and Bullinger, L. and Valent, P. and Wasik, M.A. and Huang, J. and Skorski, T.
Blood 132 (1): 67-77. 5 July 2018

SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt, K. and Kranz, A. and Fohgrub, J. and Jolly, A. and Bledau, A.S. and Di Virgilio, M. and Lesche, M. and Dahl, A. and Höfer, T. and Stewart, A.F. and Waskow, C.
Blood 131 (12): 1311-1324. 22 March 2018

Initiation of acute graft-versus-host disease by angiogenesis.
Riesner, K. and Shi, Y. and Jacobi, A. and Kräter, M. and Kalupa, M. and McGearey, A. and Mertlitz, S. and Cordes, S. and Schrezenmeier, J.F. and Mengwasser, J. and Westphal, S. and Perez-Hernandez, D. and Schmitt, C. and Dittmar, G. and Guck, J. and Penack, O.
Blood 129 (14): 2021-2032. 6 April 2017

Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia.
Qu, Y. and Siggens, L. and Cordeddu, L. and Gaidzik, V.I. and Karlsson, K. and Bullinger, L. and Döhner, K. and Ekwall, K. and Lehmann, S. and Lennartsson, A.
Blood 129 (7): e13-e25. 16 February 2017

Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J. and Neuenschwander, M. and Yu, Y. and Däbritz, J.H.M. and Neuendorff, N.R. and Schleich, K. and Bittner, A. and Milanovic, M. and Beuster, G. and Radetzki, S. and Specker, E. and Reimann, M. and Rosenbauer, F. and Mathas, S. and Lohneis, P. and Hummel, M. and Dörken, B. and von Kries, J.P. and Lee, S. and Schmitt, C.A.
Blood 129 (1): 71-81. 5 January 2017

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri, L. and Noerenberg, D. and Young, E. and Mylonas, E. and Abdulla, M. and Frick, M. and Asmar, F. and Ljungstroem, V. and Schneider, M. and Yoshida, K. and Skaftason, A. and Pandzic, T. and Gonzalez, B. and Tasidou, A. and Waldhueter, N. and Rivas-Delgado, A. and Angelopoulou, M. and Ziepert, M. and Arends, C.M. and Couronne, L. and Lenze, D. and Baldus, C.D. and Bastard, C. and Okosun, J. and Fitzgibbon, J. and Doerken, B. and Drexler, H.G. and Roos-Weil, D. and Schmitt, C.A. and Munch-Petersen, H.D. and Zenz, T. and Hansmann, M.L. and Strefford, J.C. and Enblad, G. and Bernard, O.A. and Ralfkiaer, E. and Erlanson, M. and Korkolopoulou, P. and Hultdin, M. and Papadaki, T. and Gronbaek, K. and Lopez-Guillermo, A. and Ogawa, S. and Kueppers, R. and Stamatopoulos, K. and Stavroyianni, N. and Kanellis, G. and Rosenwald, A. and Campo, E. and Amini, R.M. and Ott, G. and Vassilakopoulos, T.P. and Hummel, M. and Rosenquist, R. and Damm, F.
Blood 128 (23): 2666-2670. 15 December 2016

In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors.
Richter, M. and Saydaminova, K. and Yumul, R. and Krishnan, R. and Liu, J. and Nagy, E.E. and Singh, M. and Izsvák, Z. and Cattaneo, R. and Uckert, W. and Palmer, D. and Ng, P. and Haworth, K.G. and Kiem, H.P. and Ehrhardt, A. and Papayannopoulou, T. and Lieber, A.
Blood 128 (18): 2206-2217. 3 November 2016

Identification of novel regulators of developmental hematopoiesis using endoglin regulatory elements as molecular probes.
Nasrallah, R. and Fast, E.M. and Solaimani, P. and Knezevic, K. and Eliades, A. and Patel, R. and Thambyrajah, R. and Unnikrishnan, A. and Thoms, J. and Beck, D. and Vink, C.S. and Smith, A. and Wong, J. and Shepherd, M. and Kent, D. and Roychoudhuri, R. and Paul, F. and Klippert, J. and Hammes, A. and Willnow, T. and Göttgens, B. and Dzierzak, E. and Zon, L.I. and Lacaud, G. and Kouskoff, V. and Pimanda, J.E.
Blood 128 (15): 1928-1939. 13 October 2016

Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy.
Herling, C.D. and Klaumünzer, M. and Rocha, C.K. and Altmüller, J. and Thiele, H. and Bahlo, J. and Kluth, S. and Crispatzu, G. and Herling, M. and Schiller, J. and Engelke, A. and Tausch, E. and Döhner, H. and Fischer, K. and Goede, V. and Nürnberg, P. and Reinhardt, H.C. and Stilgenbauer, S. and Hallek, M. and Kreuzer, K.A.
Blood 128 (3): 395-404. 21 July 2016

B cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B cell lymphoma in mice.
Knittel, G. and Liedgens, P. and Korovkina, D. and Seeger, J.M. and Al-Baldawi, Y. and Al-Maarri, M. and Fritz, C. and Vlantis, K. and Bezhanova, S. and Scheel, A.H. and Wolz, O.O. and Reimann, M. and Möller, P. and López, C. and Schlesner, M. and Lohneis, P. and Weber, A.N.R. and Trümper, L. and Staudt, L.M. and Ortmann, M. and Pasparakis, M. and Siebert, R. and Schmitt, C.A. and Klatt, A.R. and Wunderlich, F.T. and Schäfer, S.C. and Persigehl, T. and Montesinos-Rongen, M. and Odenthal, M. and Büttner, R. and Frenzel, L.P. and Kashkar, H. and Reinhardt, H.C.
Blood 127 (22): 2732-2741. 2 June 2016

Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome.
Ammann, S. and Schulz, A. and Krägeloh-Mann, I. and Dieckmann, N.M.G. and Niethammer, K. and Fuchs, S. and Eckl, K.M. and Plank, R. and Werner, R. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Bank, J. and Strauss, A. and von Bernuth, H. and Zur Stadt, U. and Grieve, S. and Griffiths, G.M. and Lehmberg, K. and Hennies, H.C. and Ehl, S.
Blood 127 (8): 997-1006. 25 February 2016

Disease evolution and outcomes in familial AML with germline CEBPA mutations.
Tawana, K. and Wang, J. and Renneville, A. and Bödör, C. and Hills, R. and Loveday, C. and Savic, A. and Van Delft, F.W. and Treleaven, J. and Georgiades, P. and Uglow, E. and Asou, N. and Uike, N. and Debeljak, M. and Jazbec, J. and Ancliff, P. and Gale, R. and Thomas, X. and Mialou, V. and Döhner, K. and Bullinger, L. and Mueller, B. and Pabst, T. and Stelljes, M. and Schlegelberger, B. and Wozniak, E. and Iqbal, S. and Okosun, J. and Araf, S. and Frank, A.K. and Lauridsen, F.B. and Porse, B. and Nerlov, C. and Owen, C. and Dokal, I. and Gribben, J. and Smith, M. and Preudhomme, C. and Chelala, C. and Cavenagh, J. and Fitzgibbon, J.
Blood 126 (10): 1214-1223. 3 September 2015

New role for the (pro)renin receptor in T cell development.
Geisberger, S. and Maschke, U. and Gebhardt, M. and Kleinewietfeld, M. and Manzel, A. and Linker, R.A. and Chidgey, A. and Dechend, R. and Nguyen, G. and Daumke, O. and Muller, D.N. and Wright, M.D. and Binger, K.J.
Blood 126 (4): 504-507. 23 July 2015

Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML-Study IV.
Saussele, S. and Krauss, M.P. and Hehlmann, R. and Lauseker, M. and Proetel, U. and Kalmanti, L. and Hanfstein, B. and Fabarius, A. and Kraemer, D. and Berdel, W.E. and Bentz, M. and Staib, P. and de Wit, M. and Wernli, M. and Zettl, F. and Hebart, H.F. and Hahn, M. and Heymanns, J. and Schmidt-Wolf, I. and Schmitz, N. and Eckart, M.J. and Gassmann, W. and Bartholomaeus, A. and Pezzutto, A. and Oppliger Leibundgut, E. and Heim, D. and Krause, S.W. and Burchert, A. and Hofmann, W.K. and Hasford, J. and Hochhaus, A. and Pfirrmann, M. and Müller, M.C.
Blood 126 (1): 42-49. 2 July 2015

Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann, A. and Grau, M. and Erdmann, T. and Merkel, O. and Sobhiafshar, U. and Anagnostopoulos, I. and Hummel, M. and Siegert, A. and Hayford, C. and Madle, H. and Wollert-Wulf, B. and Fichtner, I. and Dörken, B. and Dirnhofer, S. and Mathas, S. and Janz, M. and Emre, N.C.T. and Rosenwald, A. and Ott, G. and Lenz, P. and Tzankov, A. and Lenz, G.
Blood 125 (1): 124-132. 1 January 2015

Differential impact of allelic ratio and insertion site in FLT3-ITD–positive AML with respect to allogeneic transplantation.
Schlenk, R.F. and Kayser, S. and Bullinger, L. and Kobbe, G. and Casper, J. and Ringhoffer, M. and Held, G. and Brossart, P. and Lübbert, M. and Salih, H.R. and Kindler, T. and Horst, H.A. and Wulf, G. and Nachbaur, D. and Götze, K. and Lamparter, A. and Paschka, P. and Gaidzik, V.I. and Teleanu, V. and Späth, D. and Benner, A. and Krauter, J. and Ganser, A. and Döhner, H. and Döhner, K.
Blood 124 (23): 3441-3449. 27 November 2014

Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma.
Hoellein, A. and Fallahi, M. and Schoeffmann, S. and Steidle, S. and Schaub, F.X. and Rudelius, M. and Laitinen, I. and Nilsson, L. and Goga, A. and Peschel, C. and Nilsson, J.A. and Cleveland, J.L. and Keller, U.
Blood 124 (13): 2081-2090. 25 September 2014

Bone marrow T-cell infiltration during acute GVHD is associated with delayed B-cell recovery and function after HSCT.
Mensen, A. and Jöhrens, K. and Anagnostopoulos, I. and Demski, S. and Oey, M. and Stroux, A. and Hemmati, P. and Westermann, J. and Blau, O. and Wittenbecher, F. and Movassaghi, K. and Szyska, M. and Thomas, S. and Dörken, B. and Scheibenbogen, C. and Arnold, R. and Na, I.K.
Blood 124 (6): 963-972. 7 August 2014

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly.
Belz, K. and Schoeneberger, H. and Wehner, S. and Weigert, A. and Boenig, H. and Klingebiel, T. and Fichtner, I. and Fulda, S.
Blood 124 (2): 240-250. 10 July 2014

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai, H. and Wenzel, S.S. and Hailfinger, S. and Grau, M. and Kaergel, E. and Seitz, V. and Wollert-Wulf, B. and Pfeifer, M. and Wolf, A. and Frick, M. and Dietze, K. and Madle, H. and Tzankov, A. and Hummel, M. and Dörken, B. and Scheidereit, C. and Janz, M. and Lenz, P. and Thome, M. and Lenz, G.
Blood 122 (13): 2242-2250. 26 September 2013

Combined inhibition of PI3K-related DNA-damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas.
Shortt, J. and Martin, B.P. and Newbold, A. and Hannan, K.M. and Devlin, J.R. and Baker, A.J. and Ralli, R. and Cullinane, C. and Schmitt, C.A. and Reimann, M. and Hall, M.N. and Wall, M. and Hannan, R.D. and Pearson, R.B. and McArthur, G.A. and Johnstone, R.W.
Blood 121 (15): 2964-2974. 11 April 2013

Differently immunogenic cancers in mice induce immature myeloid cells that suppress CTL in vitro but not in vivo following transfer.
Schmidt, K. and Zilio, S. and Schmollinger, J.C. and Bronte, V. and Blankenstein, T. and Willimsky, G.
Blood 121 (10): 1740-1748. 7 March 2013

Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.
Duerschmied, D. and Suidan, G.L. and Demers, M. and Herr, N. and Carbo, C. and Brill, A. and Cifuni, S.M. and Mauler, M. and Cicko, S. and Bader, M. and Idzko, M. and Bode, C. and Wagner, D.D.
Blood 121 (6): 1008-1015. 7 February 2013

T cell receptor gene transfer exclusively to human CD8+ cells enhances tumor cell killing.
Zhou, Q. and Schneider, I.C. and Edes, I. and Honegger, A. and Bach, P. and Schoenfeld, K. and Schambach, A. and Wels, W.S. and Kneissl, S. and Uckert, W. and Buchholz, C.J.
Blood 120 (22): 4334-4342. 22 November 2012

Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10.
Meyer, I. and Kunert, S. and Schwiebert, S. and Hagedorn, I. and Italiano, J.E. and Duetting, S. and Nieswandt, B. and Bachmann, S. and Schulze, H.
Blood 120 (17): 3594-602. 25 October 2012

Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states.
Pham, T.H. and Benner, C. and Lichtinger, M. and Schwarzfischer, L. and Hu, Y. and Andreesen, R. and Chen, W. and Rehli, M.
Blood 119 (24): e161-e171. 14 June 2012

TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.
Spranger, S. and Jeremias, I. and Wilde, S. and Leisegang, M. and Staerck, L. and Mosetter, B. and Uckert, W. and Heemskerk, M.H.M. and Schendel, D.J. and Frankenberger, B.
Blood 119 (15): 3440-3449. 12 April 2012

CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling.
Hampel, F. and Ehrenberg, S. and Hojer, C. and Draeseke, A. and Marschall-Schröter, G. and Kühn, R. and Mack, B. and Gires, O. and Vahl, C.J. and Schmidt-Supprian, M. and Strobl, L.J. and Zimber-Strobl, U.
Blood 118 (24): 6321-631. 8 December 2011

Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by IRPs.
Sanchez, M. and Galy, B. and Schwanhaeusser, B. and Blake, J. and Baehr-Ivacevic, T. and Benes, V. and Selbach, M. and Muckenthaler, M.U. and Hentze, M.W.
Blood 118 (22): e168-e179. 24 November 2011

Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression.
Ghani, S. and Riemke, P. and Schoenheit, J. and Lenze, D. and Stumm, J. and Hoogenkamp, M. and Lagendijk, A. and Heinz, S. and Bonifer, C. and Bakkers, J. and Abdelilah-Seyfried, S. and Hummel, M. and Rosenbauer, F.
Blood 118 (8): 2275-2284. 25 August 2011

The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed.
Popovic, J. and Li, L.P. and Kloetzel, P.M. and Leisegang, M. and Uckert, W. and Blankenstein, T.
Blood 118 (4): 946-954. 28 July 2011

Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs.
Rehm, A. and Mensen, A. and Schradi, K. and Gerlach, K. and Wittstock, S. and Winter, S. and Buechner, G. and Doerken, B. and Lipp, M. and Höpken, U.E.
Blood 118 (4): 1020-1033. 28 July 2011

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL.
Hanash, A.M. and Kappel, L.W. and Yim, N.L. and Nejat, R.A. and Goldberg, G.L. and Smith, O.M. and Rao, U.K. and Dykstra, L. and Na, I.K. and Holland, A.M. and Dudakov, J.A. and Liu, C. and Murphy, G.F. and Leonard, W.J. and Heller, G. and van den Brink, M.R.M.
Blood 118 (2): 446-455. 14 July 2011

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.
Chan, G. and Cheung, L.S. and Yang, W. and Milyavsky, M. and Sanders, A.D. and Gu, S. and Hong, W.X. and Liu, A.X. and Wang, X. and Barbara, M. and Sharma, T. and Gavin, J. and Kutok, J.L. and Iscove, N.N. and Shannon, K.M. and Dick, J.E. and Neel, B.G. and Braun, B.S.
Blood 117 (16): 4253-4261. 21 April 2011

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.
Leddin, M. and Perrod, C. and Hoogenkamp, M. and Ghani, S. and Assi, S. and Heinz, S. and Wilson, N.K. and Follows, G. and Schoenheit, J. and Vockentanz, L. and Mosamam, A. and Chen, W. and Tenen, D.G. and Westhead, D.R. and Goettgens, B. and Bonifer, C. and Rosenbauer, F.
Blood 117 (10): 2827-2838. 10 March 2011

I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development.
Orinska, Z. and Foeger, N. and Huber, M. and Marschall, J. and Mirghomizadeh, F. and Du, X. and Scheller, M. and Rosenstiel, P. and Goldmann, T. and Bollinger, A. and Beutler, B.A. and Bulfone-Paus, S.
Blood 116 (15): 2665-2675. 14 October 2010

Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo.
Na, I.K. and Markley, J.C. and Tsai, J.J. and Yim, N.L. and Beattie, B.J. and Klose, A.D. and Holland, A.M. and Ghosh, A. and Rao, U.K. and Stephan, M.T. and Serganova, I. and Santos, E.B. and Brentjens, R.J. and Blasberg, R.G. and Sadelain, M. and van den Brink, M.R.M.
Blood 116 (11): e18-e25. 16 September 2010

CD11b is a therapy resistance- and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia.
Rhein, P. and Mitlohner, R. and Basso, G. and Gaipa, G. and Dworzak, M.N. and Kirschner-Schwabe, R. and Hagemeier, C. and Stanulla, M. and Schrappe, M. and Ludwig, W.D. and Karawajew, L. and Ratei, R.
Blood 115 (18): 3763-3771. 6 May 2010

C/EBPβ regulates transcription factors critical for proliferation and survival of multiple myeloma cells.
Pal, R. and Janz, M. and Galson, D.L. and Gries, M. and Li, S. and Johrens, K. and Anagnostopoulos, I. and Doerken, B. and Mapara, M.Y. and Borghesi, L. and Kardava, L. and Roodman, G.D. and Milcarek, C. and Lentzsch, S.
Blood 114 (18): 3890-3898. 29 October 2009

Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity.
Wilde, S. and Sommermeyer, D. and Frankenberger, B. and Schiemann, M. and Milosevic, S. and Spranger, S. and Pohla, H. and Uckert, W. and Busch, D.H. and Schendel, D.J.
Blood 114 (10): 2131-2139. 3 September 2009

Stable gene transfer and expression in cord blood-derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system.
Xue, X. and Huang, X. and Nodland, S.E. and Mates, L. and Ma, L. and Izsvak, Z. and Ivics, Z. and Lebien, T.W. and McIvor, R.S. and Wagner, J.E. and Zhou, X.
Blood 114 (7): 1319-1330. 13 August 2009

Peripheral mural cell recruitment requires cell-autonomous heparan sulfate.
Stenzel, D. and Nye, E. and Nisancioglu, M. and Adams, R.H. and Yamaguchi, Y. and Gerhardt, H.
Blood 114 (4): 915-924. 23 July 2009

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells.
Urbich, C. and Rössig, L. and Kaluza, D. and Potente, M. and Boeckel, J.N. and Knau, A. and Diehl, F. and Geng, J.G. and Hofmann, W.K. and Zeiher, A.M. and Dimmeler, S.
Blood 113 (22): 5669-5679. 28 May 2009

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation.
Jenq, R.R. and King, C.G. and Volk, C. and Suh, D. and Smith, O.M. and Rao, U.K. and Yim, N.L. and Holland, A.M. and Lu, S.X. and Zakrzewski, J.L. and Goldberg, G.L. and Diab, A. and Alpdogan, O. and Penack, O. and Na, I.K. and Kappel, L.W. and Wolchok, J.D. and Houghton, A.N. and Perales, M.A. and van den Brink, M.R.M.
Blood 113 (7): 1574-1580. 12 February 2009

BK channels in innate immune functions of neutrophils and macrophages.
Essin, K. and Gollasch, M. and Rolle, S. and Weissgerber, P. and Sausbier, M. and Bohn, E. and Autenrieth, I.B. and Ruth, P. and Luft, F.C. and Nauseef, W.M. and Kettritz, R.
Blood 113 (6): 1326-1331. 5 February 2009

CD49d provides access to 'untouched' human Foxp3+ Treg free of contaminating effector cells.
Kleinewietfeld, M. and Starke, M. and Mitri, D.D. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 113 (4): 827-836. 22 January 2009

Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3α.
Lamprecht, B. and Kreher, S. and Anagnostopoulos, I. and Joehrens, K. and Monteleone, G. and Jundt, F. and Stein, H. and Janz, M. and Doerken, B. and Mathas, S.
Blood 112 (8): 3339-3347. 15 October 2008

Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses.
Groot, F. and Welsch, S. and Sattentau, Q.J.
Blood 111 (9): 4660-3. 1 May 2008

The Y-box binding protein YB-1 is associated with progressive disease and mediates survival and drug resistance in multiple myeloma.
Chatterjee, M. and Rancso, C. and Stuehmer, T. and Eckstein, N. and Andrulis, M. and Gerecke, C. and Lorentz, H. and Royer, H.D. and Bargou, R.C.
Blood 111 (7): 3714-3722. 1 April 2008

Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.
Jeannet, G. and Scheller, M. and Scarpellino, L. and Duboux, S. and Gardiol, N. and Back, J. and Kuttler, F. and Malanchi, I. and Birchmeier, W. and Leutz, A. and Huelsken, J. and Held, W.
Blood 111 (1): 142-149. 1 January 2008

The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
Reimann, M. and Loddenkemper, C. and Rudolph, C. and Schildhauer, I. and Teichmann, B. and Stein, H. and Schlegelberger, B. and Doerken, B. and Schmitt, C.A.
Blood 110 (8): 2996-3004. 15 October 2007

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.
Borsellino, G. and Kleinewietfeld, M. and Di Mitri, D. and Sternjak, A. and Diamantini, A. and Giometto, R. and Hoepner, S. and Centonze, D. and Bernardi, G. and Dell'Acqua, M.L. and Rossini, P.M. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 110 (4): 1225-1232. 15 August 2007

NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils.
von Vietinghoff, S. and Tunnemann, G. and Eulenberg, C. and Wellner, M. and Cardoso, M.C. and Luft, F.C. and Kettritz, R.
Blood 109 (10): 4487-4493. 15 May 2007

CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity.
Höpken, U.E. and Wengner, A.M. and Loddenkemper, C. and Stein, H. and Heimesaat, M.M. and Rehm, A. and Lipp, M.
Blood 109 (3): 886-895. 1 February 2007

STAT3 and MAPK signaling maintains overexpression of the heat shock proteins 90a and b in multiple myeloma cells, which critically contribute to tumor cell survival.
Chatterjee, M. and Jain, S. and Stuehmer, T. and Andrulis, M. and Ungethuem, U. and Kuban, R.J. and Lorentz, H. and Bommert, K. and Topp, M. and Kramer, D. and Mueller-Hermelink, H. K. and Einsele, H. and Greiner, A. and Bargou, R.C.
Blood 109 (2): 720-728. 15 January 2007

Active MAC-1 (CD11b/CD18) on DC is inhibitory for full T cell activation.
Varga, G. and Balkow, S. and Wild, M.K. and Stadtbaeumer, A. and Krummen, M. and Rothoeft, T. and Higuchi, T. and Beissert, S. and Wethmar, K. and Scharffetter-Kochanek, K. and Vestweber, D. and Grabbe, S.
Blood 109 (2): 661-669. 15 January 2007

Chemokines CCL19 and CCL21 promote activation-induced cell death of antigen-responding T cells.
Yasuda, T. and Kuwabara, T. and Nakano, H. and Aritomi, K. and Onodera, T. and Lipp, M. and Takahama, Y. and Kakiuchi, T.
Blood 109 (2): 449-456. 15 January 2007

Coordination between CCR7- and CCR9-mediated chemokine signals in pre-vascular fetal thymus colonization.
Liu, C. and Saito, F. and Liu, Z. and Lei, Y. and Uehara, S. and Love, P. and Lipp, M. and Kondo, S. and Manley, N. and Takahama, Y.
Blood 108 (8): 2531-2539. 15 October 2006

Lymphomas are sensitive to perforin-dependent cytotoxic pathways despite expression of PI-9 and overexpression of bcl-2.
Godal, R. and Keilholz, U. and Uharek, L. and Letsch, A. and Asemissen, A.M. and Busse, A. and Na, I.K. and Thiel, E. and Scheibenbogen, C.
Blood 107 (8): 3205-3211. 15 April 2006

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells.
Janz, M. and Hummel, M. and Truss, M. and Wollert-Wulf, B. and Mathas, S. and Joehrens, K. and Hagemeier, C. and Bommert, K. and Stein, H. and Doerken, B. and Bargou, R.C.
Blood 107 (6): 2536-2539. 15 March 2006

Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas.
Mathas, S. and Joehrens, K. and Joos, S. and Lietz, A. and Hummel, F. and Janz, M. and Jundt, F. and Anagnostopoulos, I. and Bommert, K. and Lichter, P. and Stein, H. and Scheidereit, C. and Doerken, B.
Blood 106 (13): 4287-4293. 25 August 2005

Non-genotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma.
Stuehmer, T. and Chatterjee, M. and Hildebrandt, M. and Herrmann, P. and Gollasch, H. and Gerecke, C. and Theurich, S. and Cigliano, L. and Manz, R.A. and Daniel, P.T. and Bommert, K. and Vassilev, L.T. and Bargou, R.C.
Blood 106 : 3609-3617. 4 August 2005

Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene transduced human T cells.
Xue, S.A. and Gao, L. and Hart, D. and Gillmore, R. and Qasim, W. and Thrasher, A. and Apperley, J. and Engels, B. and Uckert, W. and Morris, E. and Stauss, H.J.
Blood 106 : 3062-3067. 14 July 2005

A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein beta and NF-kappaB activity in Hodgkin and anaplastic large cell lymphomas.
Jundt, F. and Raetzel, N. and Mueller, C. and Calkhoven, C.F. and Kley, K. and Mathas, S. and Lietz, A. and Leutz, A. and Doerken, B.
Blood 106 : 1801-1807. 1 January 2005

CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T cell subset.
Kleinewietfeld, M. and Puentes, F. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 105 (7): 2877-2886. 1 January 2005

Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis.
Koh, K.R. and Janz, M. and Mapara, M.Y. and Lemke, B. and Stirling, D. and Doerken, B. and Zenke, M. and Lentzsch, S.
Blood 105 (10): 3833-3840. 1 January 2005

Role of CCL21 in recruitment of T precursor cells to fetal thymus.
Liu, C. and Ueno, T. and Kuse, S. and Saito, F. and Nitta, T. and Piali, L. and Nakano, H. and Kakiuchi, T. and Lipp, M. and Hollander, G.A. and Takahama, Y.
Blood 105 (1): 31-39. 1 January 2005

pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1.
Rosenbauer, F. and Wagner, K. and Zhang, P. and Knobeloch, K.P. and Iwama, A. and Tenen, D.G.
Blood 103 : 4294-4301. 1 June 2004

Graft-versus-host-reactive donor CD4 cells can induce T cell-mediated rejection of the donor marrow in mixed allogeneic chimeras prepared with nonmyeloablative conditioning.
Kim, Y.M. and Mapara, M.Y. and Down, J.D. and Johnson, K.W. and Boisgerault, F. and Akiyama, Y. and Benichou, G. and Pelot, M. and Zhao, G. and Sykes, M.
Blood 103 : 732-739. 15 January 2004

Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells.
Chatterjee, M. and Stuehmer, T. and Herrmann, P. and Bommert, K. and Doerken, B. and Bargou, R.C.
Blood 104 (12): 3712-3721. 1 January 2004

Jagged1-induced notch signaling drives proliferation of multiple myeloma cells.
Jundt, F. and Schulze-Proebsting, K. and Anagnostopoulos, I. and Muehlinghaus, G. and Chatterjee, M. and Mathas, S. and Bargou, R.C. and Manz, R. and Stein, H. and Doerken, B.
Blood 103 (9): 3511-3515. 1 January 2004

Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation induces a CD8+ T cell-mediated graft-versus-tumor effect that is independent of the recognition of alloantigenic tumor targets.
Stelljes, M. and Strothotte, R. and Pauels, H.G. and Poremba, C. and Milse, M. and Specht, C. and Albring, J. and Bisping, G. and Scheffold, C. and Kammertoens, T. and Oelmann, E. and Silling, G. and Berdel, W.E. and Kienast, J.
Blood 104 (4): 1210-1216. 1 January 2004

Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors.
van den Akker, E. and van Dijk, T. and Parren-van Amelsvoort, M. and Grossmann, K.S. and Schaeper, U. and Toney-Earley, K. and Waltz, S.E. and Loewenberg, B. and von Lindern, M.
Blood 103 (12): 4457-4465. 1 January 2004

Monocyte-expressed urokinase inhibits vascular smooth muscle cell growth by activating Stat1.
Kunigal, S. and Kusch, A. and Tkachuk, N. and Tkachuk, S. and Jerke, U. and Haller, H. and Dumler, I.
Blood 102 (13): 4377-4383. 15 December 2003

Inhibition of NF-κ B by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis.
Choi, M. and Rolle, S. and Wellner, M. and Cardoso, M.C. and Scheidereit, C. and Luft, F.C. and Kettritz, R.
Blood 102 (6): 2259-2267. 15 September 2003

Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: critical role for recipient-derived IFN-gamma.
Rubio, M.T. and Kim, Y.M. and Sachs, T. and Mapara, M. and Zhao, G. and Sykes, M.
Blood 102 : 2300-2307. 15 September 2003

Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis.
Mathas, S. and Lietz, A. and Janz, M. and Hinz, M. and Jundt, F. and Scheidereit, C. and Bommert, K. and Doerken, B.
Blood 102 (3): 1028-1034. 1 August 2003

Macrophage inflammatory protein 1-alpha (MIP-1alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.
Lentzsch, S. and Gries, M. and Janz, M. and Bargou, R. and Doerken, B. and Mapara, M.Y.
Blood 101 (9): 3568-3573. 1 May 2003

Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma.
Smith, J.R. and Braziel, R.M. and Paoletti, S. and Lipp, M. and Uguccioni, M. and Rosenbaum, J.T.
Blood 101 (3): 815-821. 1 February 2003

In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp 130/STAT3 pathway.
Chatterjee, M. and Hoenemann, D. and Lentzsch, S. and Bommert, K. and Sers, C. and Herrmann, P. and Mathas, S. and Doerken, B. and Bargou, R.C.
Blood 100 (9): 3311-3318. 1 November 2002

Homozygosity mapping of a second gene locus for hereditary combined deficiency of vitamin K-dependent clotting factors to the centromeric region of chromosome 16.
Fregin, A. and Rost, S. and Wolz, W. and Krebsova, A. and Muller, C.R. and Oldenburg, J.
Blood 100 (9): 3229-3232. 1 November 2002

Generalized crystal-storing histiocytosis associated with monoclonal gammopathy: molecular analysis of a disorder with rapid clinical course and review of the literature.
Lebeau, A. and Zeindl-Eberhart, E. and Mueller, E.C. and Mueller-Hoecker, J. and Jungblut, P.R. and Emmerich, B. and Loehrs, U.
Blood 100 (5): 1817-1827. 1 September 2002

Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells.
Mapara, M.Y. and Kim, Y.M. and Wang, S.P. and Bronson, R. and Sachs, D.H. and Sykes, M.
Blood 100 : 1903-1909. 1 September 2002

In vitro susceptibility to dexamethasone- and doxorubicin-induced apoptotic cell death in context of maturation stage, responsiveness to interleukin 7, and early cytoreduction in vivo in childhood T-cell acute lymphoblastic leukemia.
Wuchter, C. and Ruppert, V. and Schrappe, M. and Doerken, B. and Ludwig, W.D. and Karawajew, L.
Blood 99 (11): 4109-4115. 1 June 2002

Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.
Jundt, F. and Anagnostopoulos, I. and Foerster, R. and Mathas, S. and Stein, H. and Doerken, B.
Blood 99 (9): 3398-3403. 1 May 2002

Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease.
Jundt, F. and Kley, K. and Anagnostopoulos, I. and Schulze-Proebsting, K. and Greiner, A. and Mathas, S. and Scheidereit, C. and Wirth, T. and Stein, H. and Doerken, B.
Blood 99 (8): 3060-3062. 15 April 2002

Human hematopoiesis in murine embryos after injecting human cord blood-derived hematopoietic stem cells into murine blastocysts.
Harder, F. and Henschler, R. and Junghahn, I. and Lamers, M.C. and Mueller, A.M.
Blood 99 (2): 719-721. 15 January 2002

Up-regulation of the chemokine receptor CCR7 in classical but not in lymphocyte-predominant Hodgkin disease correlates with distinct dissemination of neoplastic cells in lymphoid organs.
Höpken, U.E. and Foss, H.D. and Meyer, D. and Hinz, M. and Leder, K. and Stein, H. and Lipp, M.
Blood 99 (4): 1109-1116. 1 January 2002

Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration.
Podar, K. and Tai, Y.T. and Davies, F.E. and Lentzsch, S. and Sattler, M. and Hideshima, T. and Lin, B.K. and Gupta, D. and Shima, Y. and Chauhan, D. and Mitsiades, C. and Raje, N. and Richardson, P. and Anderson, K.C.
Blood 98 (2): 428-435. 15 July 2001

Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma.
Davies, F.E. and Raje, N. and Hideshima, T. and Lentzsch, S. and Young, G. and Tai, Y.T. and Lin, B. and Podar, K. and Gupta, D. and Chauhan, D. and Treon, S.P. and Richardson, P.G. and Schlossman, R.L. and Morgan, G.J. and Muller, G.W. and Stirling, D.I. and Anderson, K.C.
Blood 98 (1): 210-216. 1 July 2001

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.
Wieder, T. and Essmann, F. and Prokop, A. and Schmelz, K. and Schulze-Osthoff, K. and Beyaert, R. and Doerken, B. and Daniel, P.T.
Blood 97 (5): 1378-1387. 1 March 2001

Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.
Hinz, M. and Loeser, P. and Mathas, S. and Krappmann, D. and Dörken, B. and Scheidereit, C.
Blood 97 (9): 2798-2807. 1 January 2001

The leucine zipper region of Myb oncoprotein regulates the commitment of hematopoietic progenitors.
Karafiat, V. and Dvorakova, M. and Pajer, P. and Kralova, J. and Horejsi, Z. and Cermak, V. and Bartunek, P. and Zenke, M. and Dvorak, M.
Blood 98 (13): 3668-3676. 1 January 2001

Donor stromal cells from human blood engraft in NOD/SCID mice.
Goan, S.R. and Junghahn, I. and Wissler, M. and Becker, M. and Aumann, J. and Just, U. and Martiny-Baron, G. and Fichtner, I. and Henschler, R.
Blood 96 : 3971-3978. 1 December 2000

Inhibition of in vitro spontaneous apoptosis by IL-7 correlates with Bcl-2 up-regulation, cortical/mature immunophenotype, and better early cytoreduction of childhood T-cell acute lymphoblastic leukemia.
Karawajew, L. and Ruppert, V. and Wuchter, C. and Koesser, A. and Schrappe, M. and Doerken, B. and Ludwig, W.D.
Blood 96 : 297-306. 1 July 2000

Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group.
Schrappe, M. and Reiter, A. and Ludwig, W.D. and Harbott, J. and Zimmermann, M. and Hiddemann, W. and Niemeyer, C. and Henze, G. and Feldges, A. and Zintl, F. and Kornhuber, B. and Ritter, J. and Welte, K. and Gadner, H. and Riehm, H.
Blood 95 (11): 3310-3322. 1 June 2000

Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6.
Van Brocklyn, J.R. and Graeler, M.H. and Bernhardt, G. and Hobson, J.P. and Lipp, M. and Spiegel, S.
Blood 95 : 2624-2629. 15 April 2000

Intensive ALL-type therapy without local radiotherapy provides a 90% event-free survival for children with T-cell lymphoblastic lymphoma: a BFM group report.
Reiter, A. and Schrappe, M. and Ludwig, W.D. and Tiemann, M. and Parwaresch, R. and Zimmermann, M. and Schirg, E. and Henze, G. and Schellong, G. and Gadner, H. and Riehm, H.
Blood 95 : 416-421. 15 January 2000

A recombinant bispecific single-chain antibody, CD19 X CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes.
Loeffler, A. and Kufer, P. and Lutterbuese, R. and Zettl, F. and Daniel, P.T. and Schwenkenbecher, J.M. and Riethmueller, G. and Doerken, B. and Bargou, R.C.
Blood 95 : 2098-2103. 1 January 2000

Improved treatment results in childhood B-cell neoplasms with tailored intensification of therapy: a report of the Berlin-Frankfurt-Muenster group trial NHL-BFM 90.
Reiter, A. and Schrappe, M. and Tiemann, M. and Ludwig, W.D. and Yakisan, E. and Zimmermann, M. and Mann, G. and Chott, A. and Ebell, W. and Klingebiel, T. and Graf, N. and Kremens, B. and Mueller-Weihrich, S. and Pluess, H.J. and Zintl, F. and Henze, G. and Riehm, H.
Blood 94 : 3294-3306. 15 November 1999

Overexpression of IkappaBalpha without inhibition of NF-kappaB activity and mutations in the IkappaBalpha gene in Reed-Sternberg cells.
Emmerich, F. and Meiser, M. and Hummel, M. and Demel, G. and Foss, H.D. and Jundt, F. and Mathas, S. and Krappmann, D. and Scheidereit, C. and Stein, H. and Dörken, B.
Blood 94 : 3129-3134. 1 November 1999

Hodgkin/Reed-Sternberg cells induce fibroblasts to secrete eotaxin, a potent chemoattractant for T cells and eosinophils.
Jundt, F. and Anagnostopoulos, I. and Bommert, K. and Emmerich, F. and Mueller, G. and Foss, H.D. and Royer, H.D. and Stein, H. and Doerken, B.
Blood 94 : 2065-2071. 15 September 1999

Prednisone response is the strongest predictor of treatment outcome in infant acute lymphoblastic leukemia.
Doerdelmann, M. and Reiter, A. and Borkhardt, A. and Ludwig, W.D. and Goetz, N. and Viehmann, S. and Gadner, H. and Riehm, H. and Schrappe, M.
Blood 94 (4): 1209-1217. 15 August 1999

Expression of the death gene Bik/Nbk promotes sensitivity to drug-induced apoptosis in corticosteroid-resistant T-cell lymphoma and prevents tumor growth in severe combined immunodeficient mice.
Daniel, P.T. and Pun, K.T. and Ritschel, S. and Sturm, I. and Holler, J. and Doerken, B. and Brown, R.
Blood 94 : 1100-1107. 1 August 1999

Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the german AML cooperative group.
Buechner, T. and Hiddemann, W. and Woermann, B. and Loeffler, H. and Gassmann, W. and Haferlach, T. and Fonatsch, C. and Haase, D. and Schoch, C. and Hossfeld, D. and Lengfelder, E. and Aul, C. and Heyll, A. and Maschmeyer, G. and Ludwig, W.D. and Sauerland, M.C. and Heinecke, A.
Blood 93 : 4116-4124. 15 June 1999

Aerosolized amphotericin B inhalations as prophylaxis of invasive aspergillus infections during prolonged neutropenia: results of a prospective randomized multicenter trial.
Schwartz, S. and Behre, G. and Heinemann, V. and Wandt, H. and Schilling, E. and Arning, M. and Trittin, A. and Kern, W.V. and Boenisch, O. and Bosse, D. and Lenz, K. and Ludwig, W.D. and Hiddemann, W. and Siegert, W. and Beyer, J.
Blood 93 (11): 3654-3661. 1 June 1999

Immunotherapy of B-cell lymphoma with CD3x19 bispecific antibodies: costimulation via CD28 prevents "Veto" apoptosis of antibody-targeted cytotoxic T cells.
Daniel, P.T. and Kroidl, A. and Kopp, J. and Sturm, I. and Moldenhauer, G. and Doerken, B. and Pezzutto, A.
Blood 92 (12): 4750-4757. 15 December 1998

Growth and differentiation of human stem cell factor/erythropoietin-dependent erythroid progenitor cells in vitro.
Panzenboeck, B. and Bartunek, P. and Mapara, M.Y. and Zenke, M.
Blood 92 (10): 3658-3668. 15 November 1998

Immunophenotypic and genotypic features, clinical characteristics, and treatment outcome of adult pro-B acute lymphoblastic leukemia: Results of the German multicenter trials GMALL 03/87 and 04/89.
Ludwig, W.D. and Rieder, H. and Bartram, C.R. and Heinze, B. and Schwartz, S. and Gassmann, W. and Loeffler, H. and Hossfeld, D. and Heil, G. and Handt, S. and Heyll, A. and Diedrich, H. and Fischer, K. and Weiss, A. and Voelkers, B. and Aydemir, U. and Fonatsch, C. and Goekbuget, N. and Thiel, E. and Hoelzer, D.
Blood 92 (6): 1898-1909. 15 September 1998

The reliability and specificity of c-kit for the diagnosis of acute myeloid leukemias and undifferentiated leukemias.
Bene, M.C. and Bernier, M. and Casasnovas, R.O. and Castoldi, G. and Knapp, W. and Lanza, F. and Ludwig, W.D. and Matutes, E. and Orfao, A. and Sperling, C. and van't Veer, M.B.
Blood 92 (2): 596-599. 15 July 1998

MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11): both rearrangements are associated with a poor prognosis.
Dreyling, M.H. and Schrader, K. and Fonatsch, C. and Schlegelberger, B. and Haase, D. and Schoch, C. and Ludwig, W.D. and Loeffler, H. and Buechner, T. and Wormann, B. and Hiddemann, W. and Bohlander, S.K.
Blood 91 (12): 4662-4667. 15 June 1998

CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia.
Beltinger, C. and Kurz, E. and Boehler, T. and Schrappe, M. and Ludwig, W.D. and Debatin, K.M.
Blood 91 (10): 3943-3951. 15 May 1998

Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells.
Schumann, R.R. and Belka, C. and Reuter, D. and Lamping, N. and Kirschning, C. and Weber, J.R. and Pfeil, D.
Blood 91 (2): 577-584. 15 January 1998

Abnormal expression of the b cell homing chemokine receptor blr1 during the progression of acquired immunodeficiency syndrome.
Foerster, R. and Schweigard, G. and Johann, S. and Emrich, T. and Kremmer, E. and Nerl, C. and Lipp, M.
Blood 90 (2): 520-525. 15 July 1997

Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the german and italian multicenter therapy trials.
Borkhardt, A. and Cazzaniga, G. and Viehmann, S. and Valsecchi, M.G. and Ludwig, W.D. and Burci, L. and Mangioni, S. and Schrappe, M. and Riehm, H. and Lampert, F. and Basso, G. and Masera, G. and Harbott, J. and Biondi, A.
Blood 90 : 571-577. 1 January 1997

Monitoring of tumor cell purging after highly efficient immunomagnetic selection of CD34 cells from leukapheresis products in breast cancer patients: comparision of immunocytochemical tumor cells staining and RT-PCR.
Mapara, M.Y. and Koerner, I.J. and Hildebrandt, M. and Bargou, R.C. and Krahl, D. and Reichardt, P. and Doerken, B.
Blood 89 (1): 337-344. 1 January 1997

Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in epstein-barr virus (EBV)-related lymphoma cell lines.
Weber-Nordt, R.M. and Egen, C. and Wehinger, J. and Ludwig, W.D. and Gouilleuxgruart, V. and Mertelsmann, R. and Finke, J.
Blood 88 (3): 809-816. 1 August 1996

Lipopolysaccharide induces the rapid tyrosine phosphorylation of the mitogen-activated protein kinases erk-1 and p38 in cultured human vascular endothelial cells requiring the presence of soluble CD14.
Schumann, R.R. and Pfeil, D. and Lamping, N. and Kirschning, C. and Scherzinger, G. and Schlag, P.M. and Karawajew, L. and Herrmann, F.
Blood 87 (7): 2805-2814. 1 April 1996

Clinical features and outcome of children with first marrow relapse of acute lymphoblastic leukemia expressing BCR-ABL fusion transcripts.
Beyermann, B. and Agthe, A.G. and Adams, H.P. and Seeger, K. and Linderkamp, C. and Goetze, G. and Ludwig, W.D. and Henze, G.
Blood 87 (4): 1532-1538. 15 February 1996

High level nuclear NF-kB and Oct-2 is a common feature of cultured Hodgkin/Sternberg cells.
Bargou, R.C. and Leng, C. and Krappmann, D. and Emmerich, F. and Mapara, M.Y. and Bommert, K. and Royer, H.D. and Scheidereit, C. and Doerken, B.
Blood 87 (10): 4340-4347. 1 January 1996

Improved outcome in adult b cell acute lymphoblastic leukemia.
Hoelzer, D. and Ludwig, W.D. and Thiel, E. and Gassmann, W. and Loeffler, H. and Fonatsch, C. and Rieder, H. and Heil, G. and Heinze, B. and Arnold, R. and Hossfeld, D. and Buechner, T. and Koch, P. and Freund, M. and Hiddemann, W. and Maschmeyer, G. and Heyll, A. and Aul, C. and Faak, T. and Kuse, R. and Ittel, T.H. and Gramatzki, M. and Diedrich, H. and Kolbe, K. and Fuhr, H.G. and Fischer, K. and Schadeck-Gressel, C. and Weiss, A. and Strohscheer, I. and Metzner, B. and Fabry, U. and Gokbuget, N. and Volkers, B. and Messerer, D. and Ueberla, K.
Blood 87 (2): 495-508. 1 January 1996

Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87.
Creutzig, U. and Harbott, J. and Sperling, C. and Ritter, J. and Zimmermann, M. and Loeffler, H. and Riehm, H. and Schellong, G. and Ludwig, W.D.
Blood 86 (8): 3097-3108. 1 October 1995

The receptor tyrosine kinase p185HER2 is expressed on a subset of B-lymphoid blasts from patients with acute lymphoblastic leukemia and chronic myelogenous leukemia.
Buehring, H.J. and Sures, I. and Jallal, B. and Weiss, F.U. and Busch, F.W. and Ludwig, W.D. and Handgretinger, R. and Waller, H.D. and Ullrich, A.
Blood 86 (5): 1916-1923. 1 September 1995

The severe combined immunodeficient-human peripheral blood stem cell (SCID-huPBSC) mouse: a xenotransplant model for huPBSC-initiated hematopoiesis.
Goan, S.R. and Fichtner, I. and Just, U. and Karawajew, L. and Schultze, W. and Krause, K.P. and von Harsdorf, S. and von Schilling, C. and Herrmann, F.
Blood 86 (1): 89-100. 1 July 1995

G protein subunit G alpha16 expression is restricted to progenitor B-cells during human B-cell differentiation.
Mapara, M.Y. and Bommert, K. and Bargou, R.C. and Leng, C. and Beck, C. and Ludwig, W.D. and Gierschik, P. and Doerken, B.
Blood 85 (7): 1836-1842. 1 April 1995

Human lymphotoxin has at least equal antitumor activity in comparison to human tumor necrosis factor but is less toxic in mice.
Qin, Z. and van Tits, L.J.H. and Buurman, W.A. and Blankenstein, T.
Blood 85 : 2779-2785. 1 January 1995

Analysis of a family of cyclin-dependent kinase inhibitors: p15/mts2/ink4b, p16/mts1/ink4a, and p18 genes in acute lymphoblastic leukemia of childhood.
Takeuchi, S. and Bartram, C.R. and Seriu, T. and Miller, C.W. and Tobler, A. and Janssen, J.W. and Reiter, A. and Ludwig, W.D. and Zimmermann, M. and Schwaller, J. and Lee, E. and Miyoshi, I. and Koeffler, H.P.
Blood 86 (2): 755-760. 1 January 1995

Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission.
Janssen, J.W. and Ludwig, W.D. and Borkhardt, A. and Spadinger, U. and Rieder, H. and Fonatsch, C. and Hossfeld, D.K. and Harbott, J. and Schulz, A.S. and Repp, R. and Sykora, K.W. and Hoelzer, D. and Bartram, C.R.
Blood 84 (11): 3835-3842. 1 December 1994

Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86.
Reiter, A. and Schrappe, M. and Ludwig, W.D. and Hiddemann, W. and Sauter, S. and Henze, G. and Zimmermann, M. and Lampert, F. and Havers, W. and Niethammer, D. and Odenwald, E. and Ritter, J. and Mann, G. and Welte, K. and Gadner, H. and Riehm, H.
Blood 84 (9): 3122-3133. 1 November 1994

Expression and function of CD40 on Hodgkin and Reed-Sternberg cells and the possible relevance for hodgkin's disease.
Gruss, H.J. and Hirschstein, D. and Wright, B. and Ulrich, D. and Caliguri, M.A. and Strockbine, L. and Armitage, R.J. and Dower, S.K.
Blood 84 (7): 2305-2314. 1 October 1994

Expression of the G-protein-coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells.
Foerster, R. and Emrich, T. and Kremmer, E. and Lipp, M.
Blood 84 (3): 830-840. 1 August 1994

Mutations in the pyruvate kinase L-gene in patients with hereditary hemolytic anemia.
Lenzner, C. and Nuernberg, P. and Thiele, B.J. and Reis, A. and Brabec, V. and Sakalova, A. and Jacobasch, G.
Blood 83 (10): 2817-2822. 15 May 1994

Herpesvirus type 6 in patients undergoing bone marrow transplantation: serologic features and detection by polymerase chain reaction.
Wilborn, F. and Brinkmann, V. and Schmidt, C.A. and Neipel, F. and Gelderblom, H. and Siegert, W.
Blood 83 (10): 3052-3058. 15 May 1994

Pleiotropic effects of the CD30 ligand on CD30 expressing cells and lymphoma cell lines.
Gruss, H.J. and Boiani, N. and Williams, D.E. and Armitage, R.J. and Smith, C.A. and Goodwin, R.G.
Blood 83 (8): 2045-2056. 15 April 1994

Selective targeting of human lymphokine-activated killer cells by CD3 monoclonal antibody against the interferon-inducible high-affinity Fcgamma RI receptor (CD64) on autologous acute myeloid leukemic blast cells.
Notter, M. and Ludwig, W.D. and Bremer, S. and Thiel, E.
Blood 82 (10): 3113-3124. 15 November 1993

Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood.
Wada, M. and Bartram, C.R. and Nakamura, H. and Hachiya, M. and Chen, D.L. and Borenstein, J. and Miller, C.W. and Ludwig, L. and Hansen-Hagge, T.E. and Ludwig, W.D. and Reiter, A. and Mizoguchi, H. and Hoeffler, H.P.
Blood 82 (10): 3163-3169. 15 November 1993

Review

Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells.
Vandendriessche, T. and Ivics, Z. and Izsvak, Z. and Chuah, M.K.
Blood 114 (8): 1461-1468. 20 August 2009

Effect of transcription-factor concentrations on leukemic stem cells.
Rosenbauer, F. and Koschmieder, S. and Steidl, U. and Tenen, D.G.
Blood 106 : 1519-1524. 1 September 2005

Tumor necrosis factor ligand superfamily - involvement in the pathology of malignant lymphomas.
Gruss, H.J. and Dower, S.K.
Blood 85 (12): 3378-3404. 1 January 1995

Letter

Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
Arends, C.M. and Dimitriou, S. and Stahler, A. and Hablesreiter, R. and Strzelecka, P.M. and Stein, C.M. and Tilgner, M. and Saiki, R. and Ogawa, S. and Bullinger, L. and Modest, D.P. and Stintzing, S. and Heinemann, V. and Damm, F.
Blood 139 (10): 1593-1597. 10 March 2022

Confounding in ex vivo models of Diamond-Blackfan anemia.
Ulirsch, J.C. and Lareau, C. and Ludwig, L.S. and Mohandas, N. and Nathan, D.G. and Sankaran, V.G.
Blood 130 (9): 1165-1168. 31 August 2017

In vivo-activated CD103+ Foxp3+ Tregs: of men and mice.
Roetzschke, O. and Borsellino, G. and Battistini, L. and Falk, K. and Kleinewietfeld, M.
Blood 113 (9): 2119-2120. 26 February 2009

Hydrolysis of extracellular ATP by CD39+ Treg cells: context matters!
Kleinewietfeld, M. and Dimitri, D. and Sternjak, A. and Diamantini, A. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 111 (2): 965-966. 15 January 2008

Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma.
Martin-Subero, J.I. and Wlodarska, I. and Bastard, C. and Picquenot, J.M. and Hoeppner, J. and Giefing, M. and Klapper, W. and Siebert, R. and Mathas, S. and Joos, S. and Stein, H. and Doerken, B.
Blood 108 : 401-403. 1 July 2006

Expression of the chemokine receptors CXCR4, CXCR5, and CCR7 in primary central nervous system lymphoma.
Jahnke, K. and Coupland, S.E. and Na, I.K. and Loddenkemper, C. and Keilholz, U. and Korfel, A. and Stein, H. and Thiel, E. and Scheibenbogen, C.
Blood 106 (1): 384-385. 1 July 2005

Deletions in the long arm of chromosome 10 in lymphomas with t(14;18): A pathogenetic role of the tumor suppressor genes PTEN/MMAC1 and MXI1?
Siebert, R. and Gesk, S. and Harder, S. and Ploetz, S. and Matthiesen, P. and Grote, W. and Schlegelberger, B. and Jandrig, B. and Grasmo-Wendler, U.H. and Scherneck, S. and Rosenwald, A. and Ott, G.
Blood 92 (11): 4487-4489. 1 December 1998

Polymerase chain reaction monitoring shows a high efficacy of clinical immunomagnetic purging in patients with centroblastic- centrocytic non-Hodgkin's lymphoma.
Straka, C. and Kroner, C. and Doerken, B. and Kvalheim, G.
Blood 80 (10): 2688-2690. 15 November 1992

Editorial

CEBPA mutations in AML: site matters.
Bullinger, L.
Blood 139 (1): 6-7. 6 January 2022

Lymphotoxin-α keeps the gate open for T-cell infiltration in cHL.
Höpken, U.E.
Blood 124 (19): 2897-2898. 6 November 2014

Comment

IDH2 inhibition: another piece to the puzzle.
Bullinger, L.
Blood 133 (7): 625-626. 14 February 2019