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PPM1D truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells.
Kahn, J.D. and Miller, P.G. and Silver, A.J. and Sellar, R.S. and Bhatt, S. and Gibson, C. and McConkey, M. and Adams, D. and Mar, B. and Mertins, P. and Fereshetian, S. and Krug, K. and Zhu, H. and Letai, A. and Carr, S.A. and Doench, J. and Jaiswal, S. and Ebert, B.L.
Blood 132 (11): 1095-1105. 13 September 2018

Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice.
Hoser, D. and Schön, C. and Loddenkemper, C. and Lohneis, P. and Kühl, A.A. and Sommermann, T. and Blankenstein, T. and Willimsky, G.
Blood 132 (9): 924-934. 30 August 2018

SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt, K. and Kranz, A. and Fohgrub, J. and Jolly, A. and Bledau, A.S. and Di Virgilio, M. and Lesche, M. and Dahl, A. and Höfer, T. and Stewart, A.F. and Waskow, C.
Blood 131 (12): 1311-1324. 22 March 2018


Initiation of acute graft-versus-host disease by angiogenesis.
Riesner, K. and Shi, Y. and Jacobi, A. and Kräter, M. and Kalupa, M. and McGearey, A. and Mertlitz, S. and Cordes, S. and Schrezenmeier, J.F. and Mengwasser, J. and Westphal, S. and Perez-Hernandez, D. and Schmitt, C. and Dittmar, G. and Guck, J. and Penack, O.
Blood 129 (14): 2021-2032. 6 April 2017

Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J. and Neuenschwander, M. and Yu, Y. and Däbritz, J.H.M. and Neuendorff, N.R. and Schleich, K. and Bittner, A. and Milanovic, M. and Beuster, G. and Radetzki, S. and Specker, E. and Reimann, M. and Rosenbauer, F. and Mathas, S. and Lohneis, P. and Hummel, M. and Dörken, B. and von Kries, J.P. and Lee, S. and Schmitt, C.A.
Blood 129 (1): 71-81. 12 January 2017


Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri, L. and Noerenberg, D. and Young, E. and Mylonas, E. and Abdulla, M. and Frick, M. and Asmar, F. and Ljungstroem, V. and Schneider, M. and Yoshida, K. and Skaftason, A. and Pandzic, T. and Gonzalez, B. and Tasidou, A. and Waldhueter, N. and Rivas-Delgado, A. and Angelopoulou, M. and Ziepert, M. and Arends, C.M. and Couronne, L. and Lenze, D. and Baldus, C.D. and Bastard, C. and Okosun, J. and Fitzgibbon, J. and Doerken, B. and Drexler, H.G. and Roos-Weil, D. and Schmitt, C.A. and Munch-Petersen, H.D. and Zenz, T. and Hansmann, M.L. and Strefford, J.C. and Enblad, G. and Bernard, O.A. and Ralfkiaer, E. and Erlanson, M. and Korkolopoulou, P. and Hultdin, M. and Papadaki, T. and Gronbaek, K. and Lopez-Guillermo, A. and Ogawa, S. and Kueppers, R. and Stamatopoulos, K. and Stavroyianni, N. and Kanellis, G. and Rosenwald, A. and Campo, E. and Amini, R.M. and Ott, G. and Vassilakopoulos, T.P. and Hummel, M. and Rosenquist, R. and Damm, F.
Blood 128 (23): 2666-2670. 15 December 2016

In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors.
Richter, M. and Saydaminova, K. and Yumul, R. and Krishnan, R. and Liu, J. and Nagy, E.E. and Singh, M. and Izsvák, Z. and Cattaneo, R. and Uckert, W. and Palmer, D. and Ng, P. and Haworth, K.G. and Kiem, H.P. and Ehrhardt, A. and Papayannopoulou, T. and Lieber, A.
Blood 128 (18): 2206-2217. 3 November 2016

Identification of novel regulators of developmental hematopoiesis using endoglin regulatory elements as molecular probes.
Nasrallah, R. and Fast, E.M. and Solaimani, P. and Knezevic, K. and Eliades, A. and Patel, R. and Thambyrajah, R. and Unnikrishnan, A. and Thoms, J. and Beck, D. and Vink, C.S. and Smith, A. and Wong, J. and Shepherd, M. and Kent, D. and Roychoudhuri, R. and Paul, F. and Klippert, J. and Hammes, A. and Willnow, T. and Göttgens, B. and Dzierzak, E. and Zon, L.I. and Lacaud, G. and Kouskoff, V. and Pimanda, J.E.
Blood 128 (15): 1928-1939. 13 October 2016

B cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B cell lymphoma in mice.
Knittel, G. and Liedgens, P. and Korovkina, D. and Seeger, J.M. and Al-Baldawi, Y. and Al-Maarri, M. and Fritz, C. and Vlantis, K. and Bezhanova, S. and Scheel, A.H. and Wolz, O.O. and Reimann, M. and Möller, P. and López, C. and Schlesner, M. and Lohneis, P. and Weber, A.N.R. and Trümper, L. and Staudt, L.M. and Ortmann, M. and Pasparakis, M. and Siebert, R. and Schmitt, C.A. and Klatt, A.R. and Wunderlich, F.T. and Schäfer, S.C. and Persigehl, T. and Montesinos-Rongen, M. and Odenthal, M. and Büttner, R. and Frenzel, L.P. and Kashkar, H. and Reinhardt, H.C.
Blood 127 (22): 2732-2741. 2 June 2016

Disturbed B-lymphocyte selection in autoimmune lymphoproliferative syndrome.
Janda, A. and Schwarz, K. and van der Burg, M. and Vach, W. and Ijspeert, H. and Lorenz, M.R. and Elgizouli, M. and Pieper, K. and Fisch, P. and Hagel, J. and Lorenzetti, R. and Seidl, M. and Roesler, J. and Hauck, F. and Traggiai, E. and Speckmann, C. and Rensing-Ehl, A. and Ehl, S. and Eibel, H. and Rizzi, M.
Blood 127 (18): 2193-2202. 5 May 2016


New role for the (pro)renin receptor in T cell development.
Geisberger, S. and Maschke, U. and Gebhardt, M. and Kleinewietfeld, M. and Manzel, A. and Linker, R.A. and Chidgey, A. and Dechend, R. and Nguyen, G. and Daumke, O. and Muller, D.N. and Wright, M.D. and Binger, K.J.
Blood 126 (4): 504-507. 23 July 2015

Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML-Study IV.
Saussele, S. and Krauss, M.P. and Hehlmann, R. and Lauseker, M. and Proetel, U. and Kalmanti, L. and Hanfstein, B. and Fabarius, A. and Kraemer, D. and Berdel, W.E. and Bentz, M. and Staib, P. and de Wit, M. and Wernli, M. and Zettl, F. and Hebart, H.F. and Hahn, M. and Heymanns, J. and Schmidt-Wolf, I. and Schmitz, N. and Eckart, M.J. and Gassmann, W. and Bartholomaeus, A. and Pezzutto, A. and Oppliger Leibundgut, E. and Heim, D. and Krause, S.W. and Burchert, A. and Hofmann, W.K. and Hasford, J. and Hochhaus, A. and Pfirrmann, M. and Müller, M.C.
Blood 126 (1): 42-49. 2 July 2015

Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann, A. and Grau, M. and Erdmann, T. and Merkel, O. and Sobhiafshar, U. and Anagnostopoulos, I. and Hummel, M. and Siegert, A. and Hayford, C. and Madle, H. and Wollert-Wulf, B. and Fichtner, I. and Dörken, B. and Dirnhofer, S. and Mathas, S. and Janz, M. and Emre, N.C.T. and Rosenwald, A. and Ott, G. and Lenz, P. and Tzankov, A. and Lenz, G.
Blood 125 (1): 124-132. 1 January 2015


Lymphotoxin-α keeps the gate open for T-cell infiltration in cHL.
Hoepken, U.E.
Blood 124 (19): 2897-2898. 6 November 2014

Bone marrow T-cell infiltration during acute GVHD is associated with delayed B-cell recovery and function after HSCT.
Mensen, A. and Jöhrens, K. and Anagnostopoulos, I. and Demski, S. and Oey, M. and Stroux, A. and Hemmati, P. and Westermann, J. and Blau, O. and Wittenbecher, F. and Movassaghi, K. and Szyska, M. and Thomas, S. and Dörken, B. and Scheibenbogen, C. and Arnold, R. and Na, I.K.
Blood 124 (6): 963-972. 7 August 2014

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly.
Belz, K. and Schoeneberger, H. and Wehner, S. and Weigert, A. and Boenig, H. and Klingebiel, T. and Fichtner, I. and Fulda, S.
Blood 124 (2): 240-250. 10 July 2014


IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai, H. and Wenzel, S.S. and Hailfinger, S. and Grau, M. and Kaergel, E. and Seitz, V. and Wollert-Wulf, B. and Pfeifer, M. and Wolf, A. and Frick, M. and Dietze, K. and Madle, H. and Tzankov, A. and Hummel, M. and Dörken, B. and Scheidereit, C. and Janz, M. and Lenz, P. and Thome, M. and Lenz, G.
Blood 122 (13): 2242-2250. 26 September 2013

Combined inhibition of PI3K-related DNA-damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas.
Shortt, J. and Martin, B.P. and Newbold, A. and Hannan, K.M. and Devlin, J.R. and Baker, A.J. and Ralli, R. and Cullinane, C. and Schmitt, C.A. and Reimann, M. and Hall, M.N. and Wall, M. and Hannan, R.D. and Pearson, R.B. and McArthur, G.A. and Johnstone, R.W.
Blood 121 (15): 2964-2974. 11 April 2013

Differently immunogenic cancers in mice induce immature myeloid cells that suppress CTL in vitro but not in vivo following transfer.
Schmidt, K. and Zilio, S. and Schmollinger, J.C. and Bronte, V. and Blankenstein, T. and Willimsky, G.
Blood 121 (10): 1740-1748. 7 March 2013

Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.
Duerschmied, D. and Suidan, G.L. and Demers, M. and Herr, N. and Carbo, C. and Brill, A. and Cifuni, S.M. and Mauler, M. and Cicko, S. and Bader, M. and Idzko, M. and Bode, C. and Wagner, D.D.
Blood 121 (6): 1008-1015. 7 February 2013


T cell receptor gene transfer exclusively to human CD8+ cells enhances tumor cell killing.
Zhou, Q. and Schneider, I.C. and Edes, I. and Honegger, A. and Bach, P. and Schoenfeld, K. and Schambach, A. and Wels, W.S. and Kneissl, S. and Uckert, W. and Buchholz, C.J.
Blood 120 (22): 4334-4342. 22 November 2012

Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10.
Meyer, I. and Kunert, S. and Schwiebert, S. and Hagedorn, I. and Italiano, J.E. and Duetting, S. and Nieswandt, B. and Bachmann, S. and Schulze, H.
Blood 120 (17): 3594-602. 25 October 2012

Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states.
Pham, T.H. and Benner, C. and Lichtinger, M. and Schwarzfischer, L. and Hu, Y. and Andreesen, R. and Chen, W. and Rehli, M.
Blood 119 (24): e161-e171. 14 June 2012

TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.
Spranger, S. and Jeremias, I. and Wilde, S. and Leisegang, M. and Staerck, L. and Mosetter, B. and Uckert, W. and Heemskerk, M.H.M. and Schendel, D.J. and Frankenberger, B.
Blood 119 (15): 3440-3449. 12 April 2012


CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling.
Hampel, F. and Ehrenberg, S. and Hojer, C. and Draeseke, A. and Marschall-Schroeter, G. and Kuehn, R. and Mack, B. and Gires, O. and Vahl, C.J. and Schmidt-Supprian, M. and Strobl, L.J. and Zimber-Strobl, U.
Blood 118 (24): 6321-631. 8 December 2011

Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by IRPs.
Sanchez, M. and Galy, B. and Schwanhaeusser, B. and Blake, J. and Baehr-Ivacevic, T. and Benes, V. and Selbach, M. and Muckenthaler, M.U. and Hentze, M.W.
Blood 118 (22): e168-e179. 24 November 2011

Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression.
Ghani, S. and Riemke, P. and Schoenheit, J. and Lenze, D. and Stumm, J. and Hoogenkamp, M. and Lagendijk, A. and Heinz, S. and Bonifer, C. and Bakkers, J. and Abdelilah-Seyfried, S. and Hummel, M. and Rosenbauer, F.
Blood 118 (8): 2275-2284. 25 August 2011

The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed.
Popovic, J. and Li, L.P. and Kloetzel, P.M. and Leisegang, M. and Uckert, W. and Blankenstein, T.
Blood 118 (4): 946-954. 28 July 2011

Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs.
Rehm, A. and Mensen, A. and Schradi, K. and Gerlach, K. and Wittstock, S. and Winter, S. and Buechner, G. and Doerken, B. and Lipp, M. and Hoepken, U.E.
Blood 118 (4): 1020-1033. 28 July 2011

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL.
Hanash, A.M. and Kappel, L.W. and Yim, N.L. and Nejat, R.A. and Goldberg, G.L. and Smith, O.M. and Rao, U.K. and Dykstra, L. and Na, I.K. and Holland, A.M. and Dudakov, J.A. and Liu, C. and Murphy, G.F. and Leonard, W.J. and Heller, G. and van den Brink, M.R.M.
Blood 118 (2): 446-455. 14 July 2011

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.
Leddin, M. and Perrod, C. and Hoogenkamp, M. and Ghani, S. and Assi, S. and Heinz, S. and Wilson, N.K. and Follows, G. and Schoenheit, J. and Vockentanz, L. and Mosamam, A. and Chen, W. and Tenen, D.G. and Westhead, D.R. and Goettgens, B. and Bonifer, C. and Rosenbauer, F.
Blood 117 (10): 2827-2838. 10 March 2011


I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development.
Orinska, Z. and Foeger, N. and Huber, M. and Marschall, J. and Mirghomizadeh, F. and Du, X. and Scheller, M. and Rosenstiel, P. and Goldmann, T. and Bollinger, A. and Beutler, B.A. and Bulfone-Paus, S.
Blood 116 (15): 2665-2675. 14 October 2010

Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo.
Na, I.K. and Markley, J.C. and Tsai, J.J. and Yim, N.L. and Beattie, B.J. and Klose, A.D. and Holland, A.M. and Ghosh, A. and Rao, U.K. and Stephan, M.T. and Serganova, I. and Santos, E.B. and Brentjens, R.J. and Blasberg, R.G. and Sadelain, M. and van den Brink, M.R.M.
Blood 116 (11): e18-e25. 16 September 2010

CD11b is a therapy resistance- and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia.
Rhein, P. and Mitlohner, R. and Basso, G. and Gaipa, G. and Dworzak, M.N. and Kirschner-Schwabe, R. and Hagemeier, C. and Stanulla, M. and Schrappe, M. and Ludwig, W.D. and Karawajew, L. and Ratei, R.
Blood 115 (18): 3763-3771. 6 May 2010


C/EBPβ regulates transcription factors critical for proliferation and survival of multiple myeloma cells.
Pal, R. and Janz, M. and Galson, D.L. and Gries, M. and Li, S. and Johrens, K. and Anagnostopoulos, I. and Doerken, B. and Mapara, M.Y. and Borghesi, L. and Kardava, L. and Roodman, G.D. and Milcarek, C. and Lentzsch, S.
Blood 114 (18): 3890-3898. 29 October 2009

Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity.
Wilde, S. and Sommermeyer, D. and Frankenberger, B. and Schiemann, M. and Milosevic, S. and Spranger, S. and Pohla, H. and Uckert, W. and Busch, D.H. and Schendel, D.J.
Blood 114 (10): 2131-2139. 3 September 2009

Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells.
Vandendriessche, T. and Ivics, Z. and Izsvak, Z. and Chuah, M.K.
Blood 114 (8): 1461-1468. 20 August 2009

Stable gene transfer and expression in cord blood-derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system.
Xue, X. and Huang, X. and Nodland, S.E. and Mates, L. and Ma, L. and Izsvak, Z. and Ivics, Z. and Lebien, T.W. and McIvor, R.S. and Wagner, J.E. and Zhou, X.
Blood 114 (7): 1319-1330. 13 August 2009

Peripheral mural cell recruitment requires cell-autonomous heparan sulfate.
Stenzel, D. and Nye, E. and Nisancioglu, M. and Adams, R.H. and Yamaguchi, Y. and Gerhardt, H.
Blood 114 (4): 915-924. 23 July 2009

In vivo-activated CD103+ Foxp3+ Tregs: of men and mice.
Roetzschke, O. and Borsellino, G. and Battistini, L. and Falk, K. and Kleinewietfeld, M.
Blood 113 (9): 2119-2120. 26 February 2009

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation.
Jenq, R.R. and King, C.G. and Volk, C. and Suh, D. and Smith, O.M. and Rao, U.K. and Yim, N.L. and Holland, A.M. and Lu, S.X. and Zakrzewski, J.L. and Goldberg, G.L. and Diab, A. and Alpdogan, O. and Penack, O. and Na, I.K. and Kappel, L.W. and Wolchok, J.D. and Houghton, A.N. and Perales, M.A. and van den Brink, M.R.M.
Blood 113 (7): 1574-1580. 12 February 2009

BK channels in innate immune functions of neutrophils and macrophages.
Essin, K. and Gollasch, M. and Rolle, S. and Weissgerber, P. and Sausbier, M. and Bohn, E. and Autenrieth, I.B. and Ruth, P. and Luft, F.C. and Nauseef, W.M. and Kettritz, R.
Blood 113 (6): 1326-1331. 5 February 2009

CD49d provides access to 'untouched' human Foxp3+ Treg free of contaminating effector cells.
Kleinewietfeld, M. and Starke, M. and Mitri, D.D. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 113 (4): 827-836. 22 January 2009


Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3α.
Lamprecht, B. and Kreher, S. and Anagnostopoulos, I. and Joehrens, K. and Monteleone, G. and Jundt, F. and Stein, H. and Janz, M. and Doerken, B. and Mathas, S.
Blood 112 (8): 3339-3347. 15 October 2008

The Y-box binding protein YB-1 is associated with progressive disease and mediates survival and drug resistance in multiple myeloma.
Chatterjee, M. and Rancso, C. and Stuehmer, T. and Eckstein, N. and Andrulis, M. and Gerecke, C. and Lorentz, H. and Royer, H.D. and Bargou, R.C.
Blood 111 (7): 3714-3722. 1 April 2008

Hydrolysis of extracellular ATP by CD39+ Treg cells: context matters!
Kleinewietfeld, M. and Dimitri, D. and Sternjak, A. and Diamantini, A. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 111 (2): 965-966. 15 January 2008

Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.
Jeannet, G. and Scheller, M. and Scarpellino, L. and Duboux, S. and Gardiol, N. and Back, J. and Kuttler, F. and Malanchi, I. and Birchmeier, W. and Leutz, A. and Huelsken, J. and Held, W.
Blood 111 (1): 142-149. 1 January 2008


The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
Reimann, M. and Loddenkemper, C. and Rudolph, C. and Schildhauer, I. and Teichmann, B. and Stein, H. and Schlegelberger, B. and Doerken, B. and Schmitt, C.A.
Blood 110 (8): 2996-3004. 15 October 2007

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.
Borsellino, G. and Kleinewietfeld, M. and Di Mitri, D. and Sternjak, A. and Diamantini, A. and Giometto, R. and Hoepner, S. and Centonze, D. and Bernardi, G. and Dell'Acqua, M.L. and Rossini, P.M. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 110 (4): 1225-1232. 15 August 2007

NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils.
von Vietinghoff, S. and Tuennemann, G. and Eulenberg, C. and Wellner, M. and Cardoso, M.C. and Luft, F.C. and Kettritz, R.
Blood 109 (10): 4487-4493. 15 May 2007

CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity.
Hoepken, U.E. and Wengner, A.M. and Loddenkemper, C. and Stein, H. and Heimesaat, M.M. and Rehm, A. and Lipp, M.
Blood 109 (3): 886-895. 1 February 2007

STAT3 and MAPK signaling maintains overexpression of the heat shock proteins 90a and b in multiple myeloma cells, which critically contribute to tumor cell survival.
Chatterjee, M. and Jain, S. and Stuehmer, T. and Andrulis, M. and Ungethuem, U. and Kuban, R.J. and Lorentz, H. and Bommert, K. and Topp, M. and Kramer, D. and Mueller-Hermelink, H. K. and Einsele, H. and Greiner, A. and Bargou, R.C.
Blood 109 (2): 720-728. 15 January 2007

Active MAC-1 (CD11b/CD18) on DC is inhibitory for full T cell activation.
Varga, G. and Balkow, S. and Wild, M.K. and Stadtbaeumer, A. and Krummen, M. and Rothoeft, T. and Higuchi, T. and Beissert, S. and Wethmar, K. and Scharffetter-Kochanek, K. and Vestweber, D. and Grabbe, S.
Blood 109 (2): 661-669. 15 January 2007

Chemokines CCL19 and CCL21 promote activation-induced cell death of antigen-responding T cells.
Yasuda, T. and Kuwabara, T. and Nakano, H. and Aritomi, K. and Onodera, T. and Lipp, M. and Takahama, Y. and Kakiuchi, T.
Blood 109 (2): 449-456. 15 January 2007


Coordination between CCR7- and CCR9-mediated chemokine signals in pre-vascular fetal thymus colonization.
Liu, C. and Saito, F. and Liu, Z. and Lei, Y. and Uehara, S. and Love, P. and Lipp, M. and Kondo, S. and Manley, N. and Takahama, Y.
Blood 108 (8): 2531-2539. 15 October 2006

Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma.
Martin-Subero, J.I. and Wlodarska, I. and Bastard, C. and Picquenot, J.M. and Hoeppner, J. and Giefing, M. and Klapper, W. and Siebert, R. and Mathas, S. and Joos, S. and Stein, H. and Doerken, B.
Blood 108 : 401-403. 1 July 2006

Lymphomas are sensitive to perforin-dependent cytotoxic pathways despite expression of PI-9 and overexpression of bcl-2.
Godal, R. and Keilholz, U. and Uharek, L. and Letsch, A. and Asemissen, A.M. and Busse, A. and Na, I.K. and Thiel, E. and Scheibenbogen, C.
Blood 107 (8): 3205-3211. 15 April 2006

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells.
Janz, M. and Hummel, M. and Truss, M. and Wollert-Wulf, B. and Mathas, S. and Joehrens, K. and Hagemeier, C. and Bommert, K. and Stein, H. and Doerken, B. and Bargou, R.C.
Blood 107 (6): 2536-2539. 15 March 2006


Effect of transcription-factor concentrations on leukemic stem cells.
Rosenbauer, F. and Koschmieder, S. and Steidl, U. and Tenen, D.G.
Blood 106 : 1519-1524. 1 September 2005

Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas.
Mathas, S. and Joehrens, K. and Joos, S. and Lietz, A. and Hummel, F. and Janz, M. and Jundt, F. and Anagnostopoulos, I. and Bommert, K. and Lichter, P. and Stein, H. and Scheidereit, C. and Doerken, B.
Blood 106 (13): 4287-4293. 25 August 2005

Non-genotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma.
Stuehmer, T. and Chatterjee, M. and Hildebrandt, M. and Herrmann, P. and Gollasch, H. and Gerecke, C. and Theurich, S. and Cigliano, L. and Manz, R.A. and Daniel, P.T. and Bommert, K. and Vassilev, L.T. and Bargou, R.C.
Blood 106 : 3609-3617. 4 August 2005

Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene transduced human T cells.
Xue, S.A. and Gao, L. and Hart, D. and Gillmore, R. and Qasim, W. and Thrasher, A. and Apperley, J. and Engels, B. and Uckert, W. and Morris, E. and Stauss, H.J.
Blood 106 : 3062-3067. 14 July 2005

Expression of the chemokine receptors CXCR4, CXCR5, and CCR7 in primary central nervous system lymphoma.
Jahnke, K. and Coupland, S.E. and Na, I.K. and Loddenkemper, C. and Keilholz, U. and Korfel, A. and Stein, H. and Thiel, E. and Scheibenbogen, C.
Blood 106 (1): 384-385. 1 July 2005

A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein beta and NF-kappaB activity in Hodgkin and anaplastic large cell lymphomas.
Jundt, F. and Raetzel, N. and Mueller, C. and Calkhoven, C.F. and Kley, K. and Mathas, S. and Lietz, A. and Leutz, A. and Doerken, B.
Blood 106 : 1801-1807. 1 January 2005

CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T cell subset.
Kleinewietfeld, M. and Puentes, F. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 105 (7): 2877-2886. 1 January 2005

Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis.
Koh, K.R. and Janz, M. and Mapara, M.Y. and Lemke, B. and Stirling, D. and Doerken, B. and Zenke, M. and Lentzsch, S.
Blood 105 (10): 3833-3840. 1 January 2005

Role of CCL21 in recruitment of T precursor cells to fetal thymus.
Liu, C. and Ueno, T. and Kuse, S. and Saito, F. and Nitta, T. and Piali, L. and Nakano, H. and Kakiuchi, T. and Lipp, M. and Hollander, G.A. and Takahama, Y.
Blood 105 (1): 31-39. 1 January 2005


pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1.
Rosenbauer, F. and Wagner, K. and Zhang, P. and Knobeloch, K.P. and Iwama, A. and Tenen, D.G.
Blood 103 : 4294-4301. 1 June 2004

Graft-versus-host-reactive donor CD4 cells can induce T cell-mediated rejection of the donor marrow in mixed allogeneic chimeras prepared with nonmyeloablative conditioning.
Kim, Y.M. and Mapara, M.Y. and Down, J.D. and Johnson, K.W. and Boisgerault, F. and Akiyama, Y. and Benichou, G. and Pelot, M. and Zhao, G. and Sykes, M.
Blood 103 : 732-739. 15 January 2004

Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells.
Chatterjee, M. and Stuehmer, T. and Herrmann, P. and Bommert, K. and Doerken, B. and Bargou, R.C.
Blood 104 (12): 3712-3721. 1 January 2004

Jagged1-induced notch signaling drives proliferation of multiple myeloma cells.
Jundt, F. and Schulze-Proebsting, K. and Anagnostopoulos, I. and Muehlinghaus, G. and Chatterjee, M. and Mathas, S. and Bargou, R.C. and Manz, R. and Stein, H. and Doerken, B.
Blood 103 (9): 3511-3515. 1 January 2004

Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation induces a CD8+ T cell-mediated graft-versus-tumor effect that is independent of the recognition of alloantigenic tumor targets.
Stelljes, M. and Strothotte, R. and Pauels, H.G. and Poremba, C. and Milse, M. and Specht, C. and Albring, J. and Bisping, G. and Scheffold, C. and Kammertoens, T. and Oelmann, E. and Silling, G. and Berdel, W.E. and Kienast, J.
Blood 104 (4): 1210-1216. 1 January 2004

Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors.
van den Akker, E. and van Dijk, T. and Parren-van Amelsvoort, M. and Grossmann, K.S. and Schaeper, U. and Toney-Earley, K. and Waltz, S.E. and Loewenberg, B. and von Lindern, M.
Blood 103 (12): 4457-4465. 1 January 2004


Monocyte-expressed urokinase inhibits vascular smooth muscle cell growth by activating Stat1.
Kunigal, S. and Kusch, A. and Tkachuk, N. and Tkachuk, S. and Jerke, U. and Haller, H. and Dumler, I.
Blood 102 (13): 4377-4383. 15 December 2003

Inhibition of NF-κ B by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis.
Choi, M. and Rolle, S. and Wellner, M. and Cardoso, M.C. and Scheidereit, C. and Luft, F.C. and Kettritz, R.
Blood 102 (6): 2259-2267. 15 September 2003

Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: critical role for recipient-derived IFN-gamma.
Rubio, M.T. and Kim, Y.M. and Sachs, T. and Mapara, M. and Zhao, G. and Sykes, M.
Blood 102 : 2300-2307. 15 September 2003

Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis.
Mathas, S. and Lietz, A. and Janz, M. and Hinz, M. and Jundt, F. and Scheidereit, C. and Bommert, K. and Doerken, B.
Blood 102 (3): 1028-1034. 1 August 2003

Macrophage inflammatory protein 1-alpha (MIP-1alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.
Lentzsch, S. and Gries, M. and Janz, M. and Bargou, R. and Doerken, B. and Mapara, M.Y.
Blood 101 (9): 3568-3573. 1 May 2003

Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma.
Smith, J.R. and Braziel, R.M. and Paoletti, S. and Lipp, M. and Uguccioni, M. and Rosenbaum, J.T.
Blood 101 (3): 815-821. 1 February 2003


In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp 130/STAT3 pathway.
Chatterjee, M. and Hoenemann, D. and Lentzsch, S. and Bommert, K. and Sers, C. and Herrmann, P. and Mathas, S. and Doerken, B. and Bargou, R.C.
Blood 100 (9): 3311-3318. 1 November 2002

Homozygosity mapping of a second gene locus for hereditary combined deficiency of vitamin K-dependent clotting factors to the centromeric region of chromosome 16.
Fregin, A. and Rost, S. and Wolz, W. and Krebsova, A. and Muller, C.R. and Oldenburg, J.
Blood 100 (9): 3229-3232. 1 November 2002

Generalized crystal-storing histiocytosis associated with monoclonal gammopathy: molecular analysis of a disorder with rapid clinical course and review of the literature.
Lebeau, A. and Zeindl-Eberhart, E. and Mueller, E.C. and Mueller-Hoecker, J. and Jungblut, P.R. and Emmerich, B. and Loehrs, U.
Blood 100 (5): 1817-1827. 1 September 2002

Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells.
Mapara, M.Y. and Kim, Y.M. and Wang, S.P. and Bronson, R. and Sachs, D.H. and Sykes, M.
Blood 100 : 1903-1909. 1 September 2002

In vitro susceptibility to dexamethasone- and doxorubicin-induced apoptotic cell death in context of maturation stage, responsiveness to interleukin 7, and early cytoreduction in vivo in childhood T-cell acute lymphoblastic leukemia.
Wuchter, C. and Ruppert, V. and Schrappe, M. and Doerken, B. and Ludwig, W.D. and Karawajew, L.
Blood 99 (11): 4109-4115. 1 June 2002

Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.
Jundt, F. and Anagnostopoulos, I. and Foerster, R. and Mathas, S. and Stein, H. and Doerken, B.
Blood 99 (9): 3398-3403. 1 May 2002

Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease.
Jundt, F. and Kley, K. and Anagnostopoulos, I. and Schulze-Proebsting, K. and Greiner, A. and Mathas, S. and Scheidereit, C. and Wirth, T. and Stein, H. and Doerken, B.
Blood 99 (8): 3060-3062. 15 April 2002

Human hematopoiesis in murine embryos after injecting human cord blood-derived hematopoietic stem cells into murine blastocysts.
Harder, F. and Henschler, R. and Junghahn, I. and Lamers, M.C. and Mueller, A.M.
Blood 99 (2): 719-721. 15 January 2002

Up-regulation of the chemokine receptor CCR7 in classical but not in lymphocyte-predominant Hodgkin disease correlates with distinct dissemination of neoplastic cells in lymphoid organs.
Hoepken, U.E. and Foss, H.D. and Meyer, D. and Hinz, M. and Leder, K. and Stein, H. and Lipp, M.
Blood 99 (4): 1109-1116. 1 January 2002


Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration.
Podar, K. and Tai, Y.T. and Davies, F.E. and Lentzsch, S. and Sattler, M. and Hideshima, T. and Lin, B.K. and Gupta, D. and Shima, Y. and Chauhan, D. and Mitsiades, C. and Raje, N. and Richardson, P. and Anderson, K.C.
Blood 98 (2): 428-435. 15 July 2001

Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma.
Davies, F.E. and Raje, N. and Hideshima, T. and Lentzsch, S. and Young, G. and Tai, Y.T. and Lin, B. and Podar, K. and Gupta, D. and Chauhan, D. and Treon, S.P. and Richardson, P.G. and Schlossman, R.L. and Morgan, G.J. and Muller, G.W. and Stirling, D.I. and Anderson, K.C.
Blood 98 (1): 210-216. 1 July 2001

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.
Wieder, T. and Essmann, F. and Prokop, A. and Schmelz, K. and Schulze-Osthoff, K. and Beyaert, R. and Doerken, B. and Daniel, P.T.
Blood 97 (5): 1378-1387. 1 March 2001

Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.
Hinz, M. and Loeser, P. and Mathas, S. and Krappmann, D. and Doerken, B. and Scheidereit, C.
Blood 97 (9): 2798-2807. 1 January 2001

The leucine zipper region of Myb oncoprotein regulates the commitment of hematopoietic progenitors.
Karafiat, V. and Dvorakova, M. and Pajer, P. and Kralova, J. and Horejsi, Z. and Cermak, V. and Bartunek, P. and Zenke, M. and Dvorak, M.
Blood 98 (13): 3668-3676. 1 January 2001


Donor stromal cells from human blood engraft in NOD/SCID mice.
Goan, S.R. and Junghahn, I. and Wissler, M. and Becker, M. and Aumann, J. and Just, U. and Martiny-Baron, G. and Fichtner, I. and Henschler, R.
Blood 96 : 3971-3978. 1 December 2000

Inhibition of in vitro spontaneous apoptosis by IL-7 correlates with Bcl-2 up-regulation, cortical/mature immunophenotype, and better early cytoreduction of childhood T-cell acute lymphoblastic leukemia.
Karawajew, L. and Ruppert, V. and Wuchter, C. and Koesser, A. and Schrappe, M. and Doerken, B. and Ludwig, W.D.
Blood 96 : 297-306. 1 July 2000

Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group.
Schrappe, M. and Reiter, A. and Ludwig, W.D. and Harbott, J. and Zimmermann, M. and Hiddemann, W. and Niemeyer, C. and Henze, G. and Feldges, A. and Zintl, F. and Kornhuber, B. and Ritter, J. and Welte, K. and Gadner, H. and Riehm, H.
Blood 95 (11): 3310-3322. 1 June 2000

Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6.
Van Brocklyn, J.R. and Graeler, M.H. and Bernhardt, G. and Hobson, J.P. and Lipp, M. and Spiegel, S.
Blood 95 : 2624-2629. 15 April 2000

Intensive ALL-type therapy without local radiotherapy provides a 90% event-free survival for children with T-cell lymphoblastic lymphoma: a BFM group report.
Reiter, A. and Schrappe, M. and Ludwig, W.D. and Tiemann, M. and Parwaresch, R. and Zimmermann, M. and Schirg, E. and Henze, G. and Schellong, G. and Gadner, H. and Riehm, H.
Blood 95 : 416-421. 15 January 2000

A recombinant bispecific single-chain antibody, CD19 X CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes.
Loeffler, A. and Kufer, P. and Lutterbuese, R. and Zettl, F. and Daniel, P.T. and Schwenkenbecher, J.M. and Riethmueller, G. and Doerken, B. and Bargou, R.C.
Blood 95 : 2098-2103. 1 January 2000


Improved treatment results in childhood B-cell neoplasms with tailored intensification of therapy: a report of the Berlin-Frankfurt-Muenster group trial NHL-BFM 90.
Reiter, A. and Schrappe, M. and Tiemann, M. and Ludwig, W.D. and Yakisan, E. and Zimmermann, M. and Mann, G. and Chott, A. and Ebell, W. and Klingebiel, T. and Graf, N. and Kremens, B. and Mueller-Weihrich, S. and Pluess, H.J. and Zintl, F. and Henze, G. and Riehm, H.
Blood 94 : 3294-3306. 15 November 1999

Overexpression of IkappaBalpha without inhibition of NF-kappaB activity and mutations in the IkappaBalpha gene in Reed-Sternberg cells.
Emmerich, F. and Meiser, M. and Hummel, M. and Demel, G. and Foss, H.D. and Jundt, F. and Mathas, S. and Krappmann, D. and Scheidereit, C. and Stein, H. and Doerken, B.
Blood 94 : 3129-3134. 1 November 1999

Hodgkin/Reed-Sternberg cells induce fibroblasts to secrete eotaxin, a potent chemoattractant for T cells and eosinophils.
Jundt, F. and Anagnostopoulos, I. and Bommert, K. and Emmerich, F. and Mueller, G. and Foss, H.D. and Royer, H.D. and Stein, H. and Doerken, B.
Blood 94 : 2065-2071. 15 September 1999

Prednisone response is the strongest predictor of treatment outcome in infant acute lymphoblastic leukemia.
Doerdelmann, M. and Reiter, A. and Borkhardt, A. and Ludwig, W.D. and Goetz, N. and Viehmann, S. and Gadner, H. and Riehm, H. and Schrappe, M.
Blood 94 (4): 1209-1217. 15 August 1999

Expression of the death gene Bik/Nbk promotes sensitivity to drug-induced apoptosis in corticosteroid-resistant T-cell lymphoma and prevents tumor growth in severe combined immunodeficient mice.
Daniel, P.T. and Pun, K.T. and Ritschel, S. and Sturm, I. and Holler, J. and Doerken, B. and Brown, R.
Blood 94 : 1100-1107. 1 August 1999

Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the german AML cooperative group.
Buechner, T. and Hiddemann, W. and Woermann, B. and Loeffler, H. and Gassmann, W. and Haferlach, T. and Fonatsch, C. and Haase, D. and Schoch, C. and Hossfeld, D. and Lengfelder, E. and Aul, C. and Heyll, A. and Maschmeyer, G. and Ludwig, W.D. and Sauerland, M.C. and Heinecke, A.
Blood 93 : 4116-4124. 15 June 1999

Aerosolized amphotericin B inhalations as prophylaxis of invasive aspergillus infections during prolonged neutropenia: results of a prospective randomized multicenter trial.
Schwartz, S. and Behre, G. and Heinemann, V. and Wandt, H. and Schilling, E. and Arning, M. and Trittin, A. and Kern, W.V. and Boenisch, O. and Bosse, D. and Lenz, K. and Ludwig, W.D. and Hiddemann, W. and Siegert, W. and Beyer, J.
Blood 93 (11): 3654-3661. 1 June 1999


Immunotherapy of B-cell lymphoma with CD3x19 bispecific antibodies: costimulation via CD28 prevents "Veto" apoptosis of antibody-targeted cytotoxic T cells.
Daniel, P.T. and Kroidl, A. and Kopp, J. and Sturm, I. and Moldenhauer, G. and Doerken, B. and Pezzutto, A.
Blood 92 (12): 4750-4757. 15 December 1998

Deletions in the long arm of chromosome 10 in lymphomas with t(14;18): A pathogenetic role of the tumor suppressor genes PTEN/MMAC1 and MXI1?
Siebert, R. and Gesk, S. and Harder, S. and Ploetz, S. and Matthiesen, P. and Grote, W. and Schlegelberger, B. and Jandrig, B. and Grasmo-Wendler, U.H. and Scherneck, S. and Rosenwald, A. and Ott, G.
Blood 92 (11): 4487-4489. 1 December 1998

Growth and differentiation of human stem cell factor/erythropoietin-dependent erythroid progenitor cells in vitro.
Panzenboeck, B. and Bartunek, P. and Mapara, M.Y. and Zenke, M.
Blood 92 (10): 3658-3668. 15 November 1998

Immunophenotypic and genotypic features, clinical characteristics, and treatment outcome of adult pro-B acute lymphoblastic leukemia: Results of the German multicenter trials GMALL 03/87 and 04/89.
Ludwig, W.D. and Rieder, H. and Bartram, C.R. and Heinze, B. and Schwartz, S. and Gassmann, W. and Loeffler, H. and Hossfeld, D. and Heil, G. and Handt, S. and Heyll, A. and Diedrich, H. and Fischer, K. and Weiss, A. and Voelkers, B. and Aydemir, U. and Fonatsch, C. and Goekbuget, N. and Thiel, E. and Hoelzer, D.
Blood 92 (6): 1898-1909. 15 September 1998

The reliability and specificity of c-kit for the diagnosis of acute myeloid leukemias and undifferentiated leukemias.
Bene, M.C. and Bernier, M. and Casasnovas, R.O. and Castoldi, G. and Knapp, W. and Lanza, F. and Ludwig, W.D. and Matutes, E. and Orfao, A. and Sperling, C. and van't Veer, M.B.
Blood 92 (2): 596-599. 15 July 1998

MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11): both rearrangements are associated with a poor prognosis.
Dreyling, M.H. and Schrader, K. and Fonatsch, C. and Schlegelberger, B. and Haase, D. and Schoch, C. and Ludwig, W.D. and Loeffler, H. and Buechner, T. and Wormann, B. and Hiddemann, W. and Bohlander, S.K.
Blood 91 (12): 4662-4667. 15 June 1998

CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia.
Beltinger, C. and Kurz, E. and Boehler, T. and Schrappe, M. and Ludwig, W.D. and Debatin, K.M.
Blood 91 (10): 3943-3951. 15 May 1998

Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells.
Schumann, R.R. and Belka, C. and Reuter, D. and Lamping, N. and Kirschning, C. and Weber, J.R. and Pfeil, D.
Blood 91 (2): 577-584. 15 January 1998


Abnormal expression of the b cell homing chemokine receptor blr1 during the progression of acquired immunodeficiency syndrome.
Foerster, R. and Schweigard, G. and Johann, S. and Emrich, T. and Kremmer, E. and Nerl, C. and Lipp, M.
Blood 90 (2): 520-525. 15 July 1997

Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the german and italian multicenter therapy trials.
Borkhardt, A. and Cazzaniga, G. and Viehmann, S. and Valsecchi, M.G. and Ludwig, W.D. and Burci, L. and Mangioni, S. and Schrappe, M. and Riehm, H. and Lampert, F. and Basso, G. and Masera, G. and Harbott, J. and Biondi, A.
Blood 90 : 571-577. 1 January 1997

Monitoring of tumor cell purging after highly efficient immunomagnetic selection of CD34 cells from leukapheresis products in breast cancer patients: comparision of immunocytochemical tumor cells staining and RT-PCR.
Mapara, M.Y. and Koerner, I.J. and Hildebrandt, M. and Bargou, R.C. and Krahl, D. and Reichardt, P. and Doerken, B.
Blood 89 (1): 337-344. 1 January 1997


Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in epstein-barr virus (EBV)-related lymphoma cell lines.
Weber-Nordt, R.M. and Egen, C. and Wehinger, J. and Ludwig, W.D. and Gouilleuxgruart, V. and Mertelsmann, R. and Finke, J.
Blood 88 (3): 809-816. 1 August 1996

Lipopolysaccharide induces the rapid tyrosine phosphorylation of the mitogen-activated protein kinases erk-1 and p38 in cultured human vascular endothelial cells requiring the presence of soluble CD14.
Schumann, R.R. and Pfeil, D. and Lamping, N. and Kirschning, C. and Scherzinger, G. and Schlag, P.M. and Karawajew, L. and Herrmann, F.
Blood 87 (7): 2805-2814. 1 April 1996

Clinical features and outcome of children with first marrow relapse of acute lymphoblastic leukemia expressing BCR-ABL fusion transcripts.
Beyermann, B. and Agthe, A.G. and Adams, H.P. and Seeger, K. and Linderkamp, C. and Goetze, G. and Ludwig, W.D. and Henze, G.
Blood 87 (4): 1532-1538. 15 February 1996

High level nuclear NF-kB and Oct-2 is a common feature of cultured Hodgkin/Sternberg cells.
Bargou, R.C. and Leng, C. and Krappmann, D. and Emmerich, F. and Mapara, M.Y. and Bommert, K. and Royer, H.D. and Scheidereit, C. and Doerken, B.
Blood 87 (10): 4340-4347. 1 January 1996

Improved outcome in adult b cell acute lymphoblastic leukemia.
Hoelzer, D. and Ludwig, W.D. and Thiel, E. and Gassmann, W. and Loeffler, H. and Fonatsch, C. and Rieder, H. and Heil, G. and Heinze, B. and Arnold, R. and Hossfeld, D. and Buechner, T. and Koch, P. and Freund, M. and Hiddemann, W. and Maschmeyer, G. and Heyll, A. and Aul, C. and Faak, T. and Kuse, R. and Ittel, T.H. and Gramatzki, M. and Diedrich, H. and Kolbe, K. and Fuhr, H.G. and Fischer, K. and Schadeck-Gressel, C. and Weiss, A. and Strohscheer, I. and Metzner, B. and Fabry, U. and Gokbuget, N. and Volkers, B. and Messerer, D. and Ueberla, K.
Blood 87 (2): 495-508. 1 January 1996


Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87.
Creutzig, U. and Harbott, J. and Sperling, C. and Ritter, J. and Zimmermann, M. and Loeffler, H. and Riehm, H. and Schellong, G. and Ludwig, W.D.
Blood 86 (8): 3097-3108. 1 October 1995

The receptor tyrosine kinase p185HER2 is expressed on a subset of B-lymphoid blasts from patients with acute lymphoblastic leukemia and chronic myelogenous leukemia.
Buehring, H.J. and Sures, I. and Jallal, B. and Weiss, F.U. and Busch, F.W. and Ludwig, W.D. and Handgretinger, R. and Waller, H.D. and Ullrich, A.
Blood 86 (5): 1916-1923. 1 September 1995

The severe combined immunodeficient-human peripheral blood stem cell (SCID-huPBSC) mouse: a xenotransplant model for huPBSC-initiated hematopoiesis.
Goan, S.R. and Fichtner, I. and Just, U. and Karawajew, L. and Schultze, W. and Krause, K.P. and von Harsdorf, S. and von Schilling, C. and Herrmann, F.
Blood 86 (1): 89-100. 1 July 1995

G protein subunit G alpha16 expression is restricted to progenitor B-cells during human B-cell differentiation.
Mapara, M.Y. and Bommert, K. and Bargou, R.C. and Leng, C. and Beck, C. and Ludwig, W.D. and Gierschik, P. and Doerken, B.
Blood 85 (7): 1836-1842. 1 April 1995

Tumor necrosis factor ligand superfamily - involvement in the pathology of malignant lymphomas.
Gruss, H.J. and Dower, S.K.
Blood 85 (12): 3378-3404. 1 January 1995

Human lymphotoxin has at least equal antitumor activity in comparison to human tumor necrosis factor but is less toxic in mice.
Qin, Z. and van Tits, L.J.H. and Buurman, W.A. and Blankenstein, T.
Blood 85 : 2779-2785. 1 January 1995

Analysis of a family of cyclin-dependent kinase inhibitors: p15/mts2/ink4b, p16/mts1/ink4a, and p18 genes in acute lymphoblastic leukemia of childhood.
Takeuchi, S. and Bartram, C.R. and Seriu, T. and Miller, C.W. and Tobler, A. and Janssen, J.W. and Reiter, A. and Ludwig, W.D. and Zimmermann, M. and Schwaller, J. and Lee, E. and Miyoshi, I. and Koeffler, H.P.
Blood 86 (2): 755-760. 1 January 1995


Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission.
Janssen, J.W. and Ludwig, W.D. and Borkhardt, A. and Spadinger, U. and Rieder, H. and Fonatsch, C. and Hossfeld, D.K. and Harbott, J. and Schulz, A.S. and Repp, R. and Sykora, K.W. and Hoelzer, D. and Bartram, C.R.
Blood 84 (11): 3835-3842. 1 December 1994

Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86.
Reiter, A. and Schrappe, M. and Ludwig, W.D. and Hiddemann, W. and Sauter, S. and Henze, G. and Zimmermann, M. and Lampert, F. and Havers, W. and Niethammer, D. and Odenwald, E. and Ritter, J. and Mann, G. and Welte, K. and Gadner, H. and Riehm, H.
Blood 84 (9): 3122-3133. 1 November 1994

Expression and function of CD40 on Hodgkin and Reed-Sternberg cells and the possible relevance for hodgkin's disease.
Gruss, H.J. and Hirschstein, D. and Wright, B. and Ulrich, D. and Caliguri, M.A. and Strockbine, L. and Armitage, R.J. and Dower, S.K.
Blood 84 (7): 2305-2314. 1 October 1994

Expression of the G-protein-coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells.
Foerster, R. and Emrich, T. and Kremmer, E. and Lipp, M.
Blood 84 (3): 830-840. 1 August 1994

Mutations in the pyruvate kinase L-gene in patients with hereditary hemolytic anemia.
Lenzner, C. and Nuernberg, P. and Thiele, B.J. and Reis, A. and Brabec, V. and Sakalova, A. and Jacobasch, G.
Blood 83 (10): 2817-2822. 15 May 1994

Herpesvirus type 6 in patients undergoing bone marrow transplantation: serologic features and detection by polymerase chain reaction.
Wilborn, F. and Brinkmann, V. and Schmidt, C.A. and Neipel, F. and Gelderblom, H. and Siegert, W.
Blood 83 (10): 3052-3058. 15 May 1994

Pleiotropic effects of the CD30 ligand on CD30 expressing cells and lymphoma cell lines.
Gruss, H.J. and Boiani, N. and Williams, D.E. and Armitage, R.J. and Smith, C.A. and Goodwin, R.G.
Blood 83 (8): 2045-2056. 15 April 1994


Selective targeting of human lymphokine-activated killer cells by CD3 monoclonal antibody against the interferon-inducible high-affinity Fcgamma RI receptor (CD64) on autologous acute myeloid leukemic blast cells.
Notter, M. and Ludwig, W.D. and Bremer, S. and Thiel, E.
Blood 82 (10): 3113-3124. 15 November 1993

Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood.
Wada, M. and Bartram, C.R. and Nakamura, H. and Hachiya, M. and Chen, D.L. and Borenstein, J. and Miller, C.W. and Ludwig, L. and Hansen-Hagge, T.E. and Ludwig, W.D. and Reiter, A. and Mizoguchi, H. and Hoeffler, H.P.
Blood 82 (10): 3163-3169. 15 November 1993


Polymerase chain reaction monitoring shows a high efficacy of clinical immunomagnetic purging in patients with centroblastic- centrocytic non-Hodgkin's lymphoma.
Straka, C. and Kroner, C. and Doerken, B. and Kvalheim, G.
Blood 80 (10): 2688-2690. 15 November 1992

This list was generated on Thu Oct 18 02:34:19 2018 CEST.
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