2026

Mutant IDH1 blocks neutropoiesis by repressing myeloid progenitor programs.
Hakobyan, Mariam, Langstein, Jens, Ramos Medina, María José, Kleinert, Emely, Schönung, Maximilian, Hartmann, Mark, Rohdjess, Hannah, Wojtarowicz, Jessica, Staeble, Sina, Türe, Melissa, Pobiedonoscew, Yasmine, Claus, Rainer, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Oakes, Christopher C., Zoldan, Katharina, Cross, Michael, Platzbecker, Uwe, Kneisel, Niclas, Raffel, Simon, Germing, Ulrich, Hoermann, Gregor, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Rippe, Karsten, Fröhling, Stefan, Pusch, Stefan, Plass, Christoph, Milsom, Michael D. and Lipka, Daniel B.
Blood 26 May 2026 (In Press)

MRD-2 in the GHSG HD21 trial assessed by a validated circulating tumor DNA sequencing assay.
Heger, Jan-Michel, Mattlener, Julia, Kaul, Helen, Ferdinandus, Justin, Schneider, Jessica, Schleifenbaum, Julia K., Schneider, Gundolf, Schaub, Valdete, Haenel, Mathias, Hellmuth, Johannes Christian, Dierlamm, Judith, Martin, Sonja, Mathas, Stephan ORCID: https://orcid.org/0000-0001-9626-1413, Meissner, Julia, Pegtel, D. Michiel, Zijlstra, Josée M., Ossowski, Anna, Becker, Kerstin, Hallek, Michael J., von Tresckow, Bastian, Borchmann, Peter and Borchmann, Sven
Blood 147 (19): 2194-2202. 7 May 2026

Clonal hematopoiesis and lymphoma-associated mutations in hematopoietic progenitors in B-cell non-Hodgkin lymphoma.
Wiegand, Laura, Silva, Patricia, Noerenberg, Daniel, Christen, Friederike, Kopp, Klara, Locher, Benjamin Nick, Löwe, Pelle, Tilgner, Marlon, Altwasser, Robert ORCID: https://orcid.org/0009-0002-6216-6068, Storzer, Vanessa, Stein, Catarina Marlene, Briest, Franziska, Arends, Christopher Maximilian, Frick, Mareike, Ihlow, Jana, Dolnik, Anna, Ishaque, Naveed ORCID: https://orcid.org/0000-0002-8426-901X, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Na, Il-Kang ORCID: https://orcid.org/0000-0001-9902-5424, Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Hablesreiter, Raphael and Damm, Frederik
Blood 147 (15): 1723-1734. 9 April 2026

Gonadal function and fertility after Hodgkin lymphoma treatment with nivolumab-AVD in the 2 GHSG NIVAHL trial.
Robertz, Anne Sophie, Bühnen, Ina, Meissner, Julia, Trautmann-Grill, Karolin, Herhaus, Peter, Halbsguth, Teresa, Schaub, Valdete, Kerkhoff, Andrea, Mathas, Stephan ORCID: https://orcid.org/0000-0001-9626-1413, Bormann, Matthias, Dickhut, Andreas, Jaworek, Christian P., Fuchs, Michael, Kobe, Carsten, Baues, Christian, Borchmann, Peter, von Tresckow, Bastian, Behringer, Karolin and Bröckelmann, Paul J. ORCID: https://orcid.org/0000-0001-9662-9900
Blood 7 April 2026 (In Press)

A CD22-specific T-cell receptor enables effective adoptive T-cell therapy for B-cell malignancies.
Rhein, Simone ORCID: https://orcid.org/0000-0002-9445-2352, Çakmak-Görür, Neşe ORCID: https://orcid.org/0000-0001-7857-2461, Grunert, Corinna ORCID: https://orcid.org/0000-0001-8376-8629, Al-Tabatabaee, Sarah Hayder Jalal, Serin, Nazli, Leisegang, Matthias ORCID: https://orcid.org/0000-0003-3692-7142, Timiliotis, Stefanos, Ohlmeier, Luisa Sophie ORCID: https://orcid.org/0000-0002-3381-3003, Freund, Cäcilia ORCID: https://orcid.org/0000-0002-9260-0032, Willimsky, Gerald ORCID: https://orcid.org/0000-0002-9693-948X, Konietschke, Frank, Kieback, Elisa ORCID: https://orcid.org/0000-0003-3831-2846, Tasian, Sarah K., Chapuy, Bjoern, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Blankenstein, Thomas ORCID: https://orcid.org/0000-0002-3357-4321, Pezzutto, Antonio ORCID: https://orcid.org/0000-0002-3246-4470 and Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947
Blood 147 (10): 1058-1069. 5 March 2026

2025

Common hereditary variants of the APOE gene and posttransplant outcome in acute myeloid leukemia.
Ronnacker, J., Grau, M., Klasmeier, M., Klesse, C., Baldauf, H., Abert, S., Berdel, A.F., Füsser, F.T., Sandmann, S., Albring, J., Reicherts, C., Call, S., Marx, J., Floeth, M., Eßeling, E., Kolloch, L., Berning, P., Scheller, A., Wethmar, K., Schmidt, H., Schlüter, B., Berdel, W.E., Ostendorf, B.N. ORCID: https://orcid.org/0000-0003-4492-9252, Tavazoie, S.F., Mikesch, J.H., Lenz, G., Fleischhauer, K., Schetelig, J., Stelljes, M. and Schliemann, C.
Blood 145 (17): 1943-1956. 24 April 2025

The chromatin accessibility landscape of pediatric AML.
Giguelay, A.M. ORCID: https://orcid.org/0000-0003-0417-1109 and Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164
Blood 145 (11): 1109-1111. 13 March 2025

Acute promyelocytic leukemia: long-term outcomes from the HARMONY project.
Voso, M.T., Guarnera, L., Lehmann, S., Döhner, K., Döhner, H., Platzbecker, U., Russell, N.H., Dillon, R.J., Thomas, I., Ossenkoppele, G.J., Haferlach, T., Vignetti, M., La Sala, E., Piciocchi, A., Fazi, P., Villaverde Ramiro, Á., Tur Giménez, L., Gurnari, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Hernandez, J.M.
Blood 145 (2): 234-243. 9 January 2025

2024

Management of immune thrombotic thrombocytopenic purpura without therapeutic plasma exchange.
Kühne, L. ORCID: https://orcid.org/0000-0002-5990-0279, Knöbl, P. ORCID: https://orcid.org/0000-0002-7909-7225, Eller, K. ORCID: https://orcid.org/0000-0002-6214-5008, Thaler, J. ORCID: https://orcid.org/0000-0002-9613-8658, Sperr, W.R., Gleixner, K., Osterholt, T. ORCID: https://orcid.org/0000-0001-5047-0252, Kaufeld, J. ORCID: https://orcid.org/0000-0001-7718-3464, Menne, J., Buxhofer-Ausch, V. ORCID: https://orcid.org/0000-0002-7369-9700, Mühlfeld, A., Seelow, E., Schreiber, A. ORCID: https://orcid.org/0000-0003-1244-6379, Todorova, P. ORCID: https://orcid.org/0000-0002-4728-224X, Cukoski, S., Jabs, W.J., Özcan, F., Gäckler, A., Schönfelder, K. ORCID: https://orcid.org/0009-0007-1072-5098, Seibert, F.S., Westhoff, T. ORCID: https://orcid.org/0000-0001-5797-834X, Schwenger, V., Eichenauer, D.A. ORCID: https://orcid.org/0000-0002-1927-3514, Völker, L.A. ORCID: https://orcid.org/0000-0002-5689-3448 and Brinkkoetter, P.T.
Blood 144 (14): 1486-1495. 3 October 2024

Making AML fly too close to the sun.
Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Krönke, J. ORCID: https://orcid.org/0000-0002-4649-0506
Blood 143 (15): 1438-1439. 11 April 2024

Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry.
Ben Hamza, A., Welters, C., Stadler, S., Brüggemann, M., Dietze, K., Brauns, O., Brümmendorf, T.H., Winkler, T.H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Rosenberger, L., Leisegang, M., Kammertöns, T., Herr, W., Moosmann, A., Strobel, J., Hackstein, H., Dornmair, K., Beier, F. and Hansmann, L.
Blood 143 (14): 1365-1378. 4 April 2024

Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022.
Baumgartner, F. ORCID: https://orcid.org/0000-0003-0768-1956, Baer, C., Bamopoulos, S.A. ORCID: https://orcid.org/0000-0002-5997-7735, Ayoub, E. ORCID: https://orcid.org/0000-0003-1321-0114, Truger, M., Meggendorfer, M., Lenk, M., Hoermann, G., Hutter, S. ORCID: https://orcid.org/0000-0003-2432-8898, Müller, H., Walter, W. ORCID: https://orcid.org/0000-0002-5083-9838, Mueller, M.L., Nadarajah, Ni., Blombery, P., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Kern, W., Haferlach, C. and Haferlach, T.
Blood 143 (12): 1139-1156. 21 March 2024

Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development.
Müller-Calleja, N. ORCID: https://orcid.org/0000-0002-0409-7474, Grunz, K., Nguyen, T.S., Posma, J., Pedrosa, D. ORCID: https://orcid.org/0000-0003-3324-7088, Meineck, M. ORCID: https://orcid.org/0000-0002-3243-2540, Hollerbach, A., Braun, J., Muth, S., Schild, H., Saar, K. ORCID: https://orcid.org/0000-0002-4483-1557, Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Krishnaswamy, S. ORCID: https://orcid.org/0000-0001-6381-4325, Royce, J., Teyton, L., Lemmermann, N.A. ORCID: https://orcid.org/0000-0001-9190-6497, Weinmann-Menke, J. ORCID: https://orcid.org/0000-0001-7344-8381, Lackner, K.J. ORCID: https://orcid.org/0000-0002-1985-7931 and Ruf, W. ORCID: https://orcid.org/0000-0002-6064-2166
Blood 143 (12): 1167-1180. 21 March 2024

Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz.
Uehata, T., Yamada, S., Ori, D., Vandenbon, A., Giladi, A., Jelinski, A., Murakawa, Y., Watanabe, H., Takeuchi, K., Toratani, K., Mino, T., Kiryu, H., Standley, D.M., Tsujimura, T., Ikawa, T., Kondoh, G., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Kawamoto, H., Rodewald, H.R., Amit, I., Yamamoto, R., Miyazaki, M. and Takeuchi, O.
Blood 143 (3): 243-257. 18 January 2024

2023

Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
Jiang, Q., Stachelscheid, J., Bloehdorn, J., Pacholewska, A., Aszyk, C.M., Grotenhuijs, F., Müller, T.A., Onder, O., Wagle, P., Herling, C.D., Kleppe, M., Wang, Z., Coombes, K.R., Robrecht, S., Dalvi, P.S., Plosnita, B., Mayer, P., Abruzzo, L.V., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Gathof, B.S., Persigehl, T., Fischer, K., Jebaraj, B.M.C., Rienhoff, H.Y., Ecker, R.C., Zhao, Y., Bruns, C.J., Stilgenbauer, S., Elenitoba-Johnson, K.S.J., Hallek, M., Schweiger, M.R., Odenthal, M., Vasyutina, E. and Herling, M.
Blood 142 (1): 44-61. 6 July 2023

Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends, C.M. ORCID: https://orcid.org/0000-0003-4417-4750, Liman, T.G., Strzelecka, P.M. ORCID: https://orcid.org/0000-0003-0226-6788, Kufner, A., Löwe, P. ORCID: https://orcid.org/0000-0002-6222-5323, Huo, S. ORCID: https://orcid.org/0000-0002-0119-7517, Stein, C.M. ORCID: https://orcid.org/0000-0002-9015-7671, Piper, S.K. ORCID: https://orcid.org/0000-0002-0147-8992, Tilgner, M. ORCID: https://orcid.org/0000-0003-3196-6214, Sperber, P.S. ORCID: https://orcid.org/0000-0002-9534-2374, Dimitriou, S., Heuschmann, P. ORCID: https://orcid.org/0000-0002-2681-3515, Hablesreiter, R., Harms, C. ORCID: https://orcid.org/0000-0002-2063-2860, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Weber, J.E. ORCID: https://orcid.org/0000-0002-1666-6021, Endres, M. ORCID: https://orcid.org/0000-0001-6520-3720 and Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173
Blood 141 (7): 787-799. 16 February 2023

2022

Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies.
Thomalla, D., Beckmann, L., Grimm, C., Oliverio, M., Meder, L., Herling, C.D., Nieper, P., Feldmann, T., Merkel, O., Lorsy, E., da Palma Guerreiro, A., von Jan, J., Kisis, I., Wasserburger, E., Claasen, J., Faitschuk-Meyer, E., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Nürnberg, P., Yang, T.P., Lienhard, M., Herwig, R., Kreuzer, K.A., Pallasch, C.P., Buettner, R., Schäfer, S.C., Hartley, J., Abken, H., Peifer, M., Kashkar, H., Knittel, G., Eichhorst, B., Ullrich, R.T., Herling, M., Reinhardt, H.C., Hallek, M., Schweiger, M.R. and Frenzel, L.P.
Blood 140 (20): 2113-2126. 17 November 2022

Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Bao, E.L., Liu, N. ORCID: https://orcid.org/0000-0002-8314-0900, Utsugisawa, T., Tseng, A.M., Myers, S.A. ORCID: https://orcid.org/0000-0001-7636-0887, Verboon, J.M. ORCID: https://orcid.org/0000-0002-4454-6043, Ulirsch, J.C., Luo, W., Muus, C., Fiorini, C., Olive, M.E. ORCID: https://orcid.org/0000-0001-8287-9474, Vockley, C.M., Munschauer, M., Hunter, A., Ogura, H., Yamamoto, T. ORCID: https://orcid.org/0000-0002-9484-3505, Inada, H., Nakagawa, S., Ozono, S. ORCID: https://orcid.org/0000-0003-0009-9365, Subramanian, V., Chiarle, R. ORCID: https://orcid.org/0000-0003-1564-8531, Glader, B., Carr, S.A., Aryee, M.J. ORCID: https://orcid.org/0000-0002-6848-1344, Kundaje, A. ORCID: https://orcid.org/0000-0003-3084-2287, Orkin, S., Regev, A., McCavit, T., Kanno, H. and Sankaran, V.G. ORCID: https://orcid.org/0000-0003-0044-443X
Blood 139 (16): 2534-2546. 21 April 2022

Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
Arends, C.M., Dimitriou, S., Stahler, A. ORCID: https://orcid.org/0000-0003-1041-0137, Hablesreiter, R., Strzelecka, P.M. ORCID: https://orcid.org/0000-0003-0226-6788, Stein, C.M. ORCID: https://orcid.org/0000-0002-9015-7671, Tilgner, M. ORCID: https://orcid.org/0000-0003-3196-6214, Saiki, R., Ogawa, S. ORCID: https://orcid.org/0000-0002-7778-5374, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Modest, D.P., Stintzing, S. ORCID: https://orcid.org/0000-0002-3297-5801, Heinemann, V. and Damm, F.
Blood 139 (10): 1593-1597. 10 March 2022

PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder, T.M., Schwarzer, A., Jayavelu, A.K., Hsu, C.J., Kirkpatrick, J. ORCID: https://orcid.org/0000-0001-9291-7294, Döhner, K., Perner, F., Eifert, T., Huber, N., Arreba-Tutusaus, P., Dolnik, A., Assi, S.A. ORCID: https://orcid.org/0000-0001-5634-1347, Nafria, M. ORCID: https://orcid.org/0000-0002-5329-7966, Jiang, L., Dai, Y.T. ORCID: https://orcid.org/0000-0001-8275-2115, Chen, Z., Chen, S.J., Kellaway, S.G. ORCID: https://orcid.org/0000-0002-4011-7460, Ptasinska, A., Ng, E.S. ORCID: https://orcid.org/0000-0002-7970-8129, Stanley, E.G., Elefanty, A.G. ORCID: https://orcid.org/0000-0001-6448-8314, Buschbeck, M., Bierhoff, H., Brodt, S. ORCID: https://orcid.org/0000-0003-1286-8766, Matziolis, G., Fischer, K.D., Hochhaus, A., Chen, C.W. ORCID: https://orcid.org/0000-0002-8737-6830, Heidenreich, O. ORCID: https://orcid.org/0000-0001-5404-6483, Mann, M., Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Ori, A. ORCID: https://orcid.org/0000-0002-3046-0871, von Eyss, B. ORCID: https://orcid.org/0000-0002-4731-6841, Bonifer, C. and Heidel, F. ORCID: https://orcid.org/0000-0003-2438-1955
Blood 139 (7): 1080-1097. 17 February 2022

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke, A.C., Doebele, C., Zindel, A., Lee, K.S. ORCID: https://orcid.org/0000-0001-7682-5736, Rieke, S.A. ORCID: https://orcid.org/0000-0002-2890-1308, Ceribelli, M., Comoglio, F. ORCID: https://orcid.org/0000-0002-8970-6610, Phelan, J.D., Wang, J.Q., Pikman, Y., Jahn, D., Häupl, B., Schneider, C., Scheich, S., Tosto, F.A., Bohnenberger, H. ORCID: https://orcid.org/0000-0003-1038-1030, Stauder, P. ORCID: https://orcid.org/0000-0002-3876-6023, Schnütgen, F. ORCID: https://orcid.org/0000-0002-2426-6685, Slabicki, M., Coulibaly, Z.A., Wolf, S., Bojarczuk, K., Chapuy, B. ORCID: https://orcid.org/0000-0002-6485-8773, Brandts, C.H. ORCID: https://orcid.org/0000-0003-1732-2535, Stroebel, P. ORCID: https://orcid.org/0000-0002-8528-8060, Lewis, C.A., Engelke, M., Xu, X. ORCID: https://orcid.org/0000-0003-1062-2092, Kim, H., Dang, T.H., Schmitz, R. ORCID: https://orcid.org/0000-0002-3348-6807, Hodson, D.J. ORCID: https://orcid.org/0000-0001-6225-2033, Stegmaier, K., Urlaub, H., Serve, H. ORCID: https://orcid.org/0000-0001-8472-5516, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Kreuz, F., Knittel, G. ORCID: https://orcid.org/0000-0001-8395-3701, Rabinowitz, J.D. ORCID: https://orcid.org/0000-0002-1247-4727, Reinhardt, H.C., Vander Heiden, M.G., Thomas, C., Staudt, L.M., Zenz, T. and Oellerich, T. ORCID: https://orcid.org/0000-0001-6570-6125
Blood 139 (4): 538-553. 27 January 2022

CEBPA mutations in AML: site matters.
Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Blood 139 (1): 6-7. 6 January 2022

2021

Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.
Schmalbrock, L.K. ORCID: https://orcid.org/0000-0002-6080-6175, Dolnik, A., Cocciardi, S., Sträng, E., Theis, F., Jahn, N., Panina, E., Blätte, T.J., Herzig, J.K., Skambraks, S., Rücker, F.G., Gaidzik, V.I., Paschka, P., Fiedler, W., Salih, H.R., Wulf, G.G., Schroeder, T., Lübbert, M., Schlenk, R.F., Thol, F., Heuser, M., Larson, R.A., Ganser, A., Stunnenberg, H.G., Minucci, S., Stone, R.M., Bloomfield, C.D., Döhner, H., Döhner, K. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Blood 137 (22): 3093-3104. 3 June 2021

Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Schrezenmeier, J.F., Richter-Pechanska, P. ORCID: https://orcid.org/0000-0001-6727-6317, Dolnik, A., Hick, T.P., Schleich, K., Cai, X., Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076, Lohneis, P., Masswig, S., Denker, S. ORCID: https://orcid.org/0000-0002-0736-6019, Busse, A. ORCID: https://orcid.org/0000-0002-3470-6947, Knittel, G., Flümann, R., Childs, D., Childs, L., Gätjens-Sanchez, A.M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Rosenwald, A., Reinhardt, H.C. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Blood 137 (20): 2785-2899. 20 May 2021

A randomized phase 3 trial of autologous vs allogeneic transplantation as part of first-line therapy in poor-risk peripheral T-NHL.
Schmitz, N., Truemper, L.H., Bouabdallah, K., Ziepert, M., Leclerc, M., Cartron, G., Jaccard, A., Reimer, P., Wagner-Drouet, E.M., Wilhelm, M., Sanhes, L., Lamy, T., de Leval, L., Rosenwald, A., Roussel, M., Kroschinsky, F.P., Lindemann, W.W., Dreger, P., Viardot, A., Milpied, N.J., Gisselbrecht, C., Wulf, G.G., Gyan, E., Gaulard, P., Bay, J.O., Glass, B., Poeschel, V., Damaj, G., Sibon, D., Delmer, A.J., Bilger, K., Banos, A., Haenel, M., Dreyling, M., Metzner, B., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Braulke, F., Friedrichs, B., Nickelsen, M., Altmann, B. and Tournilhac, O.
Blood 137 (19): 2646-2656. 13 May 2021

2020

Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial.
Kapp-Schwoerer, S., Weber, D., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Krönke, J., Theis, F., Rücker, F.G., Teleanu, M.V., Panina, E., Jahn, N., Herzig, J., Kubanek, L., Schrade, A., Göhring, G., Fiedler, W., Kindler, T, Schroeder, T., Mayer, K.T., Lübbert, M., Wattad, M., Götze, K.S. ORCID: https://orcid.org/0000-0002-6276-8002, Horst, H.A., Koller, E., Wulf, G. ORCID: https://orcid.org/0000-0002-7669-3785, Schleicher, J., Bentz, M., Krauter, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Krzykalla, J., Benner, A. ORCID: https://orcid.org/0000-0002-7238-6956, Schlenk, R.F. ORCID: https://orcid.org/0000-0003-2215-2059, Thol, F., Heuser, M., Ganser, A., Döhner, H ORCID: https://orcid.org/0000-0003-2116-5536 and Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862
Blood 136 (26): 3041-3050. 24 December 2020

Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1.
Reinke, S., Bröckelmann, P.J., Iaccarino, I., Garcia-Marquez, M., Borchmann, S., Jochims, F., Kotrova, M., Pal, K., Brüggemann, M., Hartmann, E., Sasse, S., Kobe, C., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Soekler, M., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bormann, M., Zimmermann, A., Richter, J., Fuchs, M., von Tresckow, B., Borchmann, P., Schlößer, H., von Bergwelt-Baildon, M., Rosenwald, A., Engert, A. and Klapper, W.
Blood 136 (25): 2851-2863. 17 December 2020

Noncanonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling.
Oberbeck, S. ORCID: https://orcid.org/0000-0002-0657-5281, Schrader, A., Warner, K., Jungherz, D., Crispatzu, G., von Jan, J., Chmielewski, M., Ianevski, A., Diebner, H.H. ORCID: https://orcid.org/0000-0002-7138-6372, Mayer, P., Kondo Ados, A., Wahnschaffe, L., Braun, T., Müller, T.A., Wagle, P., Bouska, A., Neumann, T., Pützer, S., Varghese, L., Pflug, N., Thelen, M. ORCID: https://orcid.org/0000-0002-2785-9726, Makalowski, J., Riet, N., Göx, H.J.M, Rappl, G., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Kotrová, M., Persigehl, T., Hopfinger, G., Hansmann, M.L., Schlößer, H. ORCID: https://orcid.org/0000-0002-1304-7719, Stilgenbauer, S., Dürig, J., Mougiakakos, D., von Bergwelt-Baildon, M., Roeder, I. ORCID: https://orcid.org/0000-0002-6741-0608, Hartmann, S., Hallek, M., Moriggl, R. ORCID: https://orcid.org/0000-0003-0918-9463, Brüggemann, M. ORCID: https://orcid.org/0000-0001-5514-5010, Aittokallio, T. ORCID: https://orcid.org/0000-0002-0886-9769, Iqbal, J., Newrzela, S., Abken, H. ORCID: https://orcid.org/0000-0002-4302-3240 and Herling, M.
Blood 136 (24): 2786-2802. 10 December 2020

Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells.
Raffel, S. ORCID: https://orcid.org/0000-0003-4671-1097, Klimmeck, D., Falcone, M. ORCID: https://orcid.org/0000-0003-0906-5735, Demir, A. ORCID: https://orcid.org/0000-0001-7327-7682, Pouya, A. ORCID: https://orcid.org/0000-0002-9458-1648, Zeisberger, P., Lutz, C., Tinelli, M., Bischel, O., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Thiede, C., Flörcken, A., Westermann, J., Ehninger, G., Ho, A.D., Müller-Tidow, C. ORCID: https://orcid.org/0000-0002-7166-5232, Gu, Z., Herrmann, C. ORCID: https://orcid.org/0000-0003-4989-4722, Krijgsveld, J. ORCID: https://orcid.org/0000-0001-7549-9326, Trumpp, A. ORCID: https://orcid.org/0000-0002-6212-3466 and Hansson, J. ORCID: https://orcid.org/0000-0001-9174-8089
Blood 136 (13): 1507-1519. 24 September 2020

Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
Yusuf, R.Z., Saez, B., Sharda, A., van Gastel, N. ORCID: https://orcid.org/0000-0002-0563-3590, Yu, V.W.C. ORCID: https://orcid.org/0000-0002-6658-0285, Baryawno, N., Scadden, E.W., Acharya, S., Chattophadhyay, S., Huang, C., Viswanathan, V. ORCID: https://orcid.org/0000-0001-9878-3629, S'aulis, D., Cobert, J., Sykes, D.B. ORCID: https://orcid.org/0000-0002-9788-0221, Keibler, M.A., Das, S., Hutchinson, J.N. ORCID: https://orcid.org/0000-0002-7804-7576, Churchill, M. ORCID: https://orcid.org/0000-0001-7202-3891, Mukherjee, S., Lee, D. ORCID: https://orcid.org/0000-0001-6828-401X, Mercier, F., Doench, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Logan, D.J., Schreiber, S., Stephanopoulos, G., Rizzo, W.B. and Scadden, D.T.
Blood 136 (11): 1303-1316. 10 September 2020

Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta.
Yvernogeau, L., Klaus, A., Maas, J., Morin-Poulard, I., Weijts, B., Schulte-Merker, S., Berezikov, E., Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290 and Robin, C.
Blood 136 (7): 831-844. 13 August 2020

Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax.
Tausch, E., Schneider, C., Robrecht, S., Zhang, C., Dolnik, A., Bloehdorn, J., Bahlo, J., Al-Sawaf, O., Ritgen, M., Fink, A.M., Eichhorst, B., Kreuzer, K.A., Tandon, M., Humphrey, K., Jiang, Y., Schary, W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mertens, D., Lurà, M.P., Kneba, M., Döhner, H., Fischer, K., Hallek, M. and Stilgenbauer, S.
Blood 135 (26): 2402-2412. 25 June 2020

2019

Measurable residual disease monitoring in acute myeloid leukemia with t(8;21)(q22;q22.1): results from the AML Study Group.
Rücker, F.G., Agrawal, M., Corbacioglu, A., Weber, D., Kapp-Schwoerer, S., Gaidzik, V.I., Jahn, N., Schroeder, T., Wattad, M., Lübbert, M., Koller, E., Kindler, T., Götze, K., Ringhoffer, M., Westermann, J., Fiedler, W., Horst, H.A., Greil, R., Schroers, R., Mayer, K., Heinicke, T., Krauter, J., Schlenk, R.F., Thol, F., Heuser, M., Ganser, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Paschka, P., Döhner, H. and Döhner, K.
Blood 134 (19): 1608-1618. 7 November 2019

IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia.
Scheffold, A., Jebaraj, B.M.C., Tausch, E., Bloehdorn, J., Ghia, P., Yahiaoui, A., Dolnik, A., Blätte, T.J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Dheenadayalan, R.P., Li, L., Schneider, C., Chen, S.S., Chiorazzi, N., Dietrich, S., Seiffert, M., Tannheimer, S., Döhner, H., Mertens, D. and Stilgenbauer, S.
Blood 134 (6): 534-547. 8 August 2019

Chronic CD30-signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells.
Sperling, S.A., Fiedler, P., Lechner, M., Pollithy, A., Ehrenberg, S., Schiefer, A.I., Kenner, L., Feuchtinger, A., Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Swinerd, G., Schmidt-Supprian, M., Strobl, L.J. and Zimber-Strobl, U.
Blood 133 (24): 2597-2609. 13 June 2019

NCAM1 (CD56) promotes leukemogenesis and confers drug resistance in AML.
Sasca, D., Szybinski, J., Schüler, A., Shah, V., Heidelberger, J., Haehnel, P.S., Dolnik, A., Kriege, O., Fehr, E.M., Gebhardt, W.H., Reid, G., Scholl, C., Theobald, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Beli, P. and Kindler, T.
Blood 133 (21): 2305-2319. 23 May 2019

Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations.
Jutzi, J.S. ORCID: https://orcid.org/0000-0002-1977-153X, Basu, T., Pellmann, M., Kaiser, S., Steinemann, D. ORCID: https://orcid.org/0000-0001-8797-0816, Sanders, M.A. ORCID: https://orcid.org/0000-0002-8575-9213, Hinai, A.S.A. ORCID: https://orcid.org/0000-0002-1118-017X, Zeilemaker, A., Bojtine Kovacs, S., Koellerer, C., Ostendorp, J., Aumann, K. ORCID: https://orcid.org/0000-0001-8178-1571, Wang, W., Raffoux, E., Cassinat, B. ORCID: https://orcid.org/0000-0002-6514-3905, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Schlegelberger, B. ORCID: https://orcid.org/0000-0001-5256-1270, Valk, P.J.M. and Pahl, H.L. ORCID: https://orcid.org/0000-0003-2857-2396
Blood 133 (16): 1766-1777. 18 April 2019

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, McShane, E. ORCID: https://orcid.org/0000-0002-7806-2063, Schulz-Beiss, K.W., Patone, G. ORCID: https://orcid.org/0000-0002-7242-0341, Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
Blood 133 (13): 1489-1494. 28 March 2019

Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients.
Christen, F., Hoyer, K., Yoshida, K., Hou, H.A., Waldhueter, N., Heuser, M., Hills, R.K., Chan, W., Hablesreiter, R., Blau, O., Ochi, Y., Klement, P., Chou, W.C., Blau, I.W., Tang, J.L., Zemojtel, T., Shiraishi, Y., Shiozawa, Y., Thol, F., Ganser, A., Löwenberg, B., Linch, D.C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Valk, P.J.M., Tien, H.F., Gale, R.E., Ogawa, S. and Damm, F.
Blood 133 (10): 1140-1151. 7 March 2019

The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma.
Wagener, R., Seufert, J., Raimondi, F., Bens, S., Kleinheinz, K., Nagel, I., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Thiele, H., Hübschmann, D. ORCID: https://orcid.org/0000-0002-6041-7049, Kohler, C.W., Nürnberg, P., Au-Yeung, R. ORCID: https://orcid.org/0000-0002-3137-0886, Burkhardt, B., Horn, H., Leoncini, L., Jaffe, E.S., Ott, G., Rymkiewicz, G., Schlesner, M. ORCID: https://orcid.org/0000-0002-5896-4086, Russell, R.B. ORCID: https://orcid.org/0000-0002-1905-4717, Klapper, W. and Siebert, R.
Blood 133 (9): 962-966. 28 February 2019

IDH2 inhibition: another piece to the puzzle.
Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Blood 133 (7): 625-626. 14 February 2019

2018

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.
Jacquelin, S., Straube, J., Cooper, L., Vu, T., Song, A., Bywater, M., Baxter, E., Heidecker, M., Wackrow, B., Porter, A., Ling, V., Green, J., Austin, R., Kazakoff, S., Waddell, N., Hesson, L.B., Pimanda, J.E., Stegelmann, F., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, K., Rampal, R.K., Heckl, D., Hill, G.R. and Lane, S.W.
Blood 132 (26): 2707-2721. 27 December 2018

Nrf2 regulates CD4(+) T cell-induced acute graft-versus-host disease in mice.
Tsai, J.J. ORCID: https://orcid.org/0000-0002-9267-4584, Velardi, E., Shono, Y. ORCID: https://orcid.org/0000-0002-0459-1659, Argyropoulos, K.V. ORCID: https://orcid.org/0000-0003-1510-5887, Holland, A.M., Smith, O.M., Yim, N.L., Rao, U.K., Kreines, F.M., Lieberman, S.R., Young, L.F., Lazrak, A., Youssef, S., Fu, Y.Y., Liu, C., Lezcano, C., Murphy, G.F., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Jenq, R.R., Hanash, A.M., Dudakov, J.A. ORCID: https://orcid.org/0000-0001-6220-5632 and van den Brink, M.R.M. ORCID: https://orcid.org/0000-0003-0696-4401
Blood 132 (26): 2763-2774. 27 December 2018

Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells.
Kabrani, E. ORCID: https://orcid.org/0000-0003-0834-9912, Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696, Tasouri, E., Sommermann, T. ORCID: https://orcid.org/0000-0003-2899-0256, Baßler, K., Ulas, T., Zenz, T., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Schultze, J.L., Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Sander, S. ORCID: https://orcid.org/0000-0003-4645-3366
Blood 132 (25): 2670-2683. 20 December 2018

IG-MYC(+) neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas.
Wagener, R., López, C., Kleinheinz, K., Bausinger, J., Aukema, S.M., Nagel, I., Toprak, U.H., Seufert, J., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Thiele, H., Schneider, C., Kolarova, J., Park, J., Hübschmann, D., Murga Penas, E.M., Drexler, H.G., Attarbaschi, A., Hovland, R., Kjeldsen, E., Kneba, M., Kontny, U., de Leval, L., Nürnberg, P., Oschlies, I., Oscier, D., Schlegelberger, B., Stilgenbauer, S., Wössmann, W., Schlesner, M., Burkhardt, B., Klapper, W., Jaffe, E.S., Küppers, R. and Siebert, R.
Blood 132 (21): 2280-2285. 22 November 2018

Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML.
Thol, F., Gabdoulline, R., Liebich, A., Klement, P., Schiller, J., Kandziora, C., Hambach, L., Stadler, M., Koenecke, C., Flintrop, M., Pankratz, M., Wichmann, M., Neziri, B., Büttner, K., Heida, B., Klesse, S., Chaturvedi, A., Kloos, A., Göhring, G., Schlegelberger, B., Gaidzik, V.I., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Fiedler, W., Heim, A., Hamwi, I., Eder, M., Krauter, J., Schlenk, R.F., Paschka, P., Döhner, K., Döhner, H., Ganser, A. and Heuser, M.
Blood 132 (16): 1703-1713. 18 October 2018

PPM1D truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells.
Kahn, J.D., Miller, P.G., Silver, A.J., Sellar, R.S., Bhatt, S., Gibson, C., McConkey, M., Adams, D., Mar, B., Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Fereshetian, S., Krug, K., Zhu, H., Letai, A., Carr, S.A., Doench, J., Jaiswal, S. and Ebert, B.L.
Blood 132 (11): 1095-1105. 13 September 2018

Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice.
Hoser, D., Schön, C., Loddenkemper, C., Lohneis, P., Kühl, A.A., Sommermann, T. ORCID: https://orcid.org/0000-0003-2899-0256, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X
Blood 132 (9): 924-934. 30 August 2018

Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.
Maifrede, S., Nieborowska-Skorska, M., Sullivan-Reed, K., Dasgupta, Y., Podszywalow-Bartnicka, P., Le, B.V., Solecka, M., Lian, Z., Belyaeva, E.A., Nersesyan, A., Machnicki, M.M., Toma, M., Chatain, N., Rydzanicz, M., Zhao, H., Jelinek, J., Piwocka, K., Sliwinski, T., Stoklosa, T., Ploski, R., Fischer, T., Sykes, S.M., Koschmieder, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Valent, P., Wasik, M.A., Huang, J. and Skorski, T.
Blood 132 (1): 67-77. 5 July 2018

SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt, K., Kranz, A., Fohgrub, J., Jolly, A., Bledau, A.S., Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793, Lesche, M., Dahl, A., Höfer, T., Stewart, A.F. and Waskow, C.
Blood 131 (12): 1311-1324. 22 March 2018

2017

Confounding in ex vivo models of Diamond-Blackfan anemia.
Ulirsch, J.C., Lareau, C. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Mohandas, N., Nathan, D.G. and Sankaran, V.G. ORCID: https://orcid.org/0000-0003-0044-443X
Blood 130 (9): 1165-1168. 31 August 2017

Initiation of acute graft-versus-host disease by angiogenesis.
Riesner, K., Shi, Y., Jacobi, A., Kräter, M., Kalupa, M., McGearey, A., Mertlitz, S., Cordes, S., Schrezenmeier, J.F., Mengwasser, J., Westphal, S., Perez-Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Guck, J. and Penack, O.
Blood 129 (14): 2021-2032. 6 April 2017

Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia.
Qu, Y., Siggens, L., Cordeddu, L., Gaidzik, V.I., Karlsson, K., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, K., Ekwall, K., Lehmann, S. and Lennartsson, A.
Blood 129 (7): e13-e25. 16 February 2017

Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J., Neuenschwander, M. ORCID: https://orcid.org/0000-0002-3114-7975, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Däbritz, J.H.M., Neuendorff, N.R., Schleich, K., Bittner, A. ORCID: https://orcid.org/0000-0001-6434-0950, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Beuster, G., Radetzki, S. ORCID: https://orcid.org/0000-0003-2688-2868, Specker, E. ORCID: https://orcid.org/0000-0002-9471-9520, Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Rosenbauer, F. ORCID: https://orcid.org/0000-0001-7977-9421, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Lohneis, P., Hummel, M., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Blood 129 (1): 71-81. 5 January 2017

2016

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri, L., Noerenberg, D., Young, E., Mylonas, E., Abdulla, M., Frick, M., Asmar, F., Ljungstroem, V., Schneider, M., Yoshida, K., Skaftason, A., Pandzic, T., Gonzalez, B., Tasidou, A., Waldhueter, N., Rivas-Delgado, A., Angelopoulou, M., Ziepert, M., Arends, C.M., Couronne, L., Lenze, D., Baldus, C.D., Bastard, C., Okosun, J., Fitzgibbon, J., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Drexler, H.G., Roos-Weil, D., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Munch-Petersen, H.D., Zenz, T., Hansmann, M.L., Strefford, J.C., Enblad, G., Bernard, O.A., Ralfkiaer, E., Erlanson, M., Korkolopoulou, P., Hultdin, M., Papadaki, T., Gronbaek, K., Lopez-Guillermo, A., Ogawa, S., Kueppers, R., Stamatopoulos, K., Stavroyianni, N., Kanellis, G., Rosenwald, A., Campo, E., Amini, R.M., Ott, G., Vassilakopoulos, T.P., Hummel, M., Rosenquist, R. and Damm, F.
Blood 128 (23): 2666-2670. 15 December 2016

In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors.
Richter, M., Saydaminova, K., Yumul, R., Krishnan, R., Liu, J., Nagy, E.E., Singh, M. ORCID: https://orcid.org/0000-0002-8626-5418, Izsvák, Z. ORCID: https://orcid.org/0000-0002-2053-2384, Cattaneo, R., Uckert, W., Palmer, D., Ng, P., Haworth, K.G., Kiem, H.P., Ehrhardt, A., Papayannopoulou, T. and Lieber, A.
Blood 128 (18): 2206-2217. 3 November 2016

Identification of novel regulators of developmental hematopoiesis using endoglin regulatory elements as molecular probes.
Nasrallah, R., Fast, E.M., Solaimani, P., Knezevic, K., Eliades, A., Patel, R., Thambyrajah, R., Unnikrishnan, A., Thoms, J., Beck, D., Vink, C.S., Smith, A., Wong, J., Shepherd, M., Kent, D., Roychoudhuri, R., Paul, F., Klippert, J., Hammes, A. ORCID: https://orcid.org/0000-0003-1663-8378, Willnow, T. ORCID: https://orcid.org/0000-0001-9515-7921, Göttgens, B., Dzierzak, E., Zon, L.I., Lacaud, G., Kouskoff, V. and Pimanda, J.E.
Blood 128 (15): 1928-1939. 13 October 2016

Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy.
Herling, C.D., Klaumünzer, M., Rocha, C.K., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Thiele, H., Bahlo, J., Kluth, S., Crispatzu, G., Herling, M., Schiller, J., Engelke, A., Tausch, E., Döhner, H., Fischer, K., Goede, V., Nürnberg, P., Reinhardt, H.C., Stilgenbauer, S., Hallek, M. and Kreuzer, K.A.
Blood 128 (3): 395-404. 21 July 2016

B cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B cell lymphoma in mice.
Knittel, G., Liedgens, P., Korovkina, D., Seeger, J.M., Al-Baldawi, Y., Al-Maarri, M., Fritz, C., Vlantis, K., Bezhanova, S., Scheel, A.H., Wolz, O.O., Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Möller, P., López, C., Schlesner, M., Lohneis, P., Weber, A.N.R., Trümper, L., Staudt, L.M., Ortmann, M., Pasparakis, M., Siebert, R., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Klatt, A.R., Wunderlich, F.T., Schäfer, S.C., Persigehl, T., Montesinos-Rongen, M., Odenthal, M., Büttner, R., Frenzel, L.P., Kashkar, H. and Reinhardt, H.C.
Blood 127 (22): 2732-2741. 2 June 2016

Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome.
Ammann, S., Schulz, A., Krägeloh-Mann, I., Dieckmann, N.M.G., Niethammer, K., Fuchs, S., Eckl, K.M. ORCID: https://orcid.org/0000-0001-8838-3998, Plank, R., Werner, R., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Thiele, H., Nürnberg, P., Bank, J., Strauss, A., von Bernuth, H., Zur Stadt, U., Grieve, S., Griffiths, G.M., Lehmberg, K., Hennies, H.C. ORCID: https://orcid.org/0000-0001-7210-2389 and Ehl, S.
Blood 127 (8): 997-1006. 25 February 2016

2015

Disease evolution and outcomes in familial AML with germline CEBPA mutations.
Tawana, K., Wang, J., Renneville, A., Bödör, C., Hills, R., Loveday, C., Savic, A., Van Delft, F.W., Treleaven, J., Georgiades, P., Uglow, E., Asou, N., Uike, N., Debeljak, M., Jazbec, J., Ancliff, P., Gale, R., Thomas, X., Mialou, V., Döhner, K., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mueller, B., Pabst, T., Stelljes, M., Schlegelberger, B., Wozniak, E., Iqbal, S., Okosun, J., Araf, S., Frank, A.K., Lauridsen, F.B., Porse, B., Nerlov, C., Owen, C., Dokal, I., Gribben, J., Smith, M., Preudhomme, C., Chelala, C., Cavenagh, J. and Fitzgibbon, J.
Blood 126 (10): 1214-1223. 3 September 2015

New role for the (pro)renin receptor in T cell development.
Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Maschke, U., Gebhardt, M., Kleinewietfeld, M. ORCID: https://orcid.org/0000-0002-2832-3149, Manzel, A., Linker, R.A., Chidgey, A., Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Nguyen, G., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Muller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Wright, M.D. and Binger, K.J. ORCID: https://orcid.org/0000-0003-1139-3308
Blood 126 (4): 504-507. 23 July 2015

Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML-Study IV.
Saussele, S., Krauss, M.P., Hehlmann, R., Lauseker, M., Proetel, U., Kalmanti, L., Hanfstein, B., Fabarius, A., Kraemer, D., Berdel, W.E., Bentz, M., Staib, P., de Wit, M., Wernli, M., Zettl, F., Hebart, H.F., Hahn, M., Heymanns, J., Schmidt-Wolf, I., Schmitz, N., Eckart, M.J., Gassmann, W., Bartholomaeus, A., Pezzutto, A. ORCID: https://orcid.org/0000-0002-3246-4470, Oppliger Leibundgut, E., Heim, D., Krause, S.W., Burchert, A., Hofmann, W.K., Hasford, J., Hochhaus, A., Pfirrmann, M. and Müller, M.C.
Blood 126 (1): 42-49. 2 July 2015

Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann, A., Grau, M., Erdmann, T., Merkel, O., Sobhiafshar, U., Anagnostopoulos, I., Hummel, M., Siegert, A., Hayford, C., Madle, H., Wollert-Wulf, B. ORCID: https://orcid.org/0009-0000-0257-4049, Fichtner, I., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Dirnhofer, S., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Emre, N.C.T., Rosenwald, A., Ott, G., Lenz, P., Tzankov, A. and Lenz, G.
Blood 125 (1): 124-132. 1 January 2015

2014

Differential impact of allelic ratio and insertion site in FLT3-ITD–positive AML with respect to allogeneic transplantation.
Schlenk, R.F., Kayser, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Kobbe, G., Casper, J., Ringhoffer, M., Held, G., Brossart, P., Lübbert, M., Salih, H.R., Kindler, T., Horst, H.A., Wulf, G., Nachbaur, D., Götze, K., Lamparter, A., Paschka, P., Gaidzik, V.I., Teleanu, V., Späth, D., Benner, A., Krauter, J., Ganser, A., Döhner, H. and Döhner, K.
Blood 124 (23): 3441-3449. 27 November 2014

Lymphotoxin-α keeps the gate open for T-cell infiltration in cHL.
Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893
Blood 124 (19): 2897-2898. 6 November 2014

Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma.
Hoellein, A., Fallahi, M., Schoeffmann, S., Steidle, S., Schaub, F.X., Rudelius, M., Laitinen, I., Nilsson, L., Goga, A., Peschel, C., Nilsson, J.A., Cleveland, J.L. and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
Blood 124 (13): 2081-2090. 25 September 2014

Bone marrow T-cell infiltration during acute GVHD is associated with delayed B-cell recovery and function after HSCT.
Mensen, A., Jöhrens, K., Anagnostopoulos, I., Demski, S., Oey, M., Stroux, A., Hemmati, P., Westermann, J., Blau, O., Wittenbecher, F., Movassaghi, K., Szyska, M. ORCID: https://orcid.org/0000-0002-4213-4600, Thomas, S., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Scheibenbogen, C., Arnold, R. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Blood 124 (6): 963-972. 7 August 2014

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly.
Belz, K., Schoeneberger, H., Wehner, S., Weigert, A., Boenig, H., Klingebiel, T., Fichtner, I. and Fulda, S.
Blood 124 (2): 240-250. 10 July 2014

SIRT1 prevents genotoxic stress-induced p53 activation in acute myeloid leukemia.
Sasca, D., Hähnel, P.S., Szybinski, J., Khawaja, K., Kriege, O., Pante, S.V., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Strand, S., Strand, D., Theobald, M. and Kindler, T.
Blood 124 (1): 121-133. 3 July 2014

Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.
Stilgenbauer, S., Schnaiter, A., Paschka, P., Zenz, T., Rossi, M., Döhner, K., Bühler, A., Böttcher, S., Ritgen, M., Kneba, M., Winkler, D., Tausch, E., Hoth, P., Edelmann, J., Mertens, D., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Bergmann, M., Kless, S., Mack, S., Jäger, U., Patten, N., Wu, L., Wenger, M.K., Fingerle-Rowson, G., Lichter, P., Cazzola, M., Wendtner, C.M., Fink, A.M., Fischer, K., Busch, R., Hallek, M. and Döhner, H.
Blood 123 (21): 3247-3254. 22 May 2014

Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy.
Hähnel, P.S., Enders, B., Sasca, D., Roos, W.P., Kaina, B., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Theobald, M. and Kindler, T.
Blood 123 (15): 2355-2366. 10 April 2014

Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.
Rapin, N., Bagger, F.O., Jendholm, J., Mora-Jensen, H., Krogh, A., Kohlmann, A., Thiede, C., Borregaard, N., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Winther, O., Theilgaard-Mönch, K. and Porse, B.T.
Blood 123 (6): 894-904. 6 February 2014

2013

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai, H., Wenzel, S.S., Hailfinger, S., Grau, M., Kaergel, E., Seitz, V., Wollert-Wulf, B. ORCID: https://orcid.org/0009-0000-0257-4049, Pfeifer, M., Wolf, A., Frick, M., Dietze, K., Madle, H., Tzankov, A., Hummel, M., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Lenz, P., Thome, M. and Lenz, G.
Blood 122 (13): 2242-2250. 26 September 2013

The value of allogeneic and autologous hematopoietic stem cell transplantation in prognostically favorable acute myeloid leukemia with double mutant CEBPA.
Schlenk, R.F., Taskesen, E., van Norden, Y., Krauter, J., Ganser, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Gaidzik, V.I., Paschka, P., Corbacioglu, A., Göhring, G., Kündgen, A., Held, G., Götze, K., Vellenga, E., Kuball, J., Schanz, U., Passweg, J., Pabst, T., Maertens, J., Ossenkoppele, G.J., Delwel, R., Döhner, H., Cornelissen, J.J., Döhner, K. and Löwenberg, B.
Blood 122 (9): 1576-1582. 29 August 2013

Human CD1c(+) dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses.
Nizzoli, G., Krietsch, J., Weick, A., Steinfelder, S. ORCID: https://orcid.org/0000-0002-8469-4251, Facciotti, F., Gruarin, P., Bianco, A., Steckel, B., Moro, M., Crosti, M., Romagnani, C., Stölzel, K., Torretta, S., Pignataro, L., Scheibenbogen, C., Neddermann, P., De Francesco, R., Abrignani, S. and Geginat, J.
Blood 122 (6): 932-942. 8 August 2013

Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia.
Krönke, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Teleanu, V., Tschürtz, F., Gaidzik, V.I., Kühn, M.W.M., Rücker, F.G., Holzmann, K., Paschka, P., Kapp-Schwörer, S., Späth, D., Kindler, T., Schittenhelm, M., Krauter, J., Ganser, A., Göhring, G., Schlegelberger, B., Schlenk, R.F., Döhner, H. and Döhner, K.
Blood 122 (1): 100-108. 4 July 2013

Clinical impact of DNMT3A mutations in younger adult patients with acute myeloid leukemia: results of the AML Study Group (AMLSG).
Gaidzik, V.I., Schlenk, R.F., Paschka, P., Stölzle, A., Späth, D., Kuendgen, A., von Lilienfeld-Toal, M., Brugger, W., Derigs, H.G., Kremers, S., Greil, R., Raghavachar, A., Ringhoffer, M., Salih, H.R., Wattad, M., Kirchen, H.G., Runde, V., Heil, G., Petzer, A.L., Girschikofsky, M., Heuser, M., Kayser, S., Goehring, G., Teleanu, M.V., Schlegelberger, B., Ganser, A., Krauter, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, H. and Döhner, K.
Blood 121 (23): 4769-77. 6 June 2013

Combined inhibition of PI3K-related DNA-damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas.
Shortt, J., Martin, B.P., Newbold, A., Hannan, K.M., Devlin, J.R., Baker, A.J., Ralli, R., Cullinane, C., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Hall, M.N., Wall, M., Hannan, R.D., Pearson, R.B., McArthur, G.A. and Johnstone, R.W.
Blood 121 (15): 2964-2974. 11 April 2013

Differently immunogenic cancers in mice induce immature myeloid cells that suppress CTL in vitro but not in vivo following transfer.
Schmidt, K. ORCID: https://orcid.org/0000-0002-0572-6199, Zilio, S., Schmollinger, J.C., Bronte, V., Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X
Blood 121 (10): 1740-1748. 7 March 2013

PBX3 is an important cofactor of HOXA9 in leukemogenesis.
Li, Zejuan, Zhang, Zhiyu, Li, Yuanyuan, Arnovitz, Stephen, Chen, Ping, Huang, Hao, Jiang, Xi, Hong, Gia-Ming, Kunjamma, Rejani B., Ren, Haomin, He, Chunjiang, Wang, Chong-Zhi, Elkahloun, Abdel G., Valk, Peter J.M., Döhner, Konstanze, Neilly, Mary Beth, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Delwel, Ruud, Löwenberg, Bob, Liu, Paul P., Morgan, Richard, Rowley, Janet D., Yuan, Chun-Su and Chen, Jianjun
Blood 121 (8): 1422-31. 21 February 2013

Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.
Duerschmied, D., Suidan, G.L., Demers, M., Herr, N., Carbo, C., Brill, A., Cifuni, S.M., Mauler, M., Cicko, S., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Idzko, M., Bode, C. and Wagner, D.D.
Blood 121 (6): 1008-1015. 7 February 2013

Secondary genetic lesions in acute myeloid leukemia with inv(16) or t(16;16): a study of the German-Austrian AML Study Group (AMLSG).
Paschka, P., Du, J., Schlenk, R.F., Gaidzik, V.I., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Corbacioglu, A., Späth, D., Kayser, S., Schlegelberger, B., Krauter, J., Ganser, A., Köhne, C.H., Held, G., von Lilienfeld-Toal, M., Kirchen, H., Rummel, M., Götze, K., Horst, H.A., Ringhoffer, M., Lübbert, M., Wattad, M., Salih, H.R., Kündgen, A., Döhner, H. and Döhner, K.
Blood 121 (1): 170-7. 3 January 2013

2012

T cell receptor gene transfer exclusively to human CD8+ cells enhances tumor cell killing.
Zhou, Q., Schneider, I.C., Edes, I., Honegger, A., Bach, P., Schoenfeld, K., Schambach, A., Wels, W.S., Kneissl, S., Uckert, W. and Buchholz, C.J.
Blood 120 (22): 4334-4342. 22 November 2012

Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10.
Meyer, I., Kunert, S., Schwiebert, S., Hagedorn, I., Italiano, J.E., Duetting, S., Nieswandt, B., Bachmann, S. and Schulze, H.
Blood 120 (17): 3594-602. 25 October 2012

Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states.
Pham, T.H., Benner, C., Lichtinger, M., Schwarzfischer, L., Hu, Y. ORCID: https://orcid.org/0000-0002-5210-5301, Andreesen, R., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627 and Rehli, M.
Blood 119 (24): e161-e171. 14 June 2012

TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.
Spranger, S., Jeremias, I., Wilde, S., Leisegang, M. ORCID: https://orcid.org/0000-0003-3692-7142, Staerck, L., Mosetter, B., Uckert, W., Heemskerk, M.H.M., Schendel, D.J. and Frankenberger, B.
Blood 119 (15): 3440-3449. 12 April 2012

2011

CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling.
Hampel, F., Ehrenberg, S., Hojer, C., Draeseke, A., Marschall-Schröter, G., Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Mack, B., Gires, O., Vahl, C.J., Schmidt-Supprian, M., Strobl, L.J. and Zimber-Strobl, U.
Blood 118 (24): 6321-631. 8 December 2011

Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by IRPs.
Sanchez, M., Galy, B., Schwanhaeusser, B., Blake, J., Baehr-Ivacevic, T., Benes, V., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Muckenthaler, M.U. and Hentze, M.W.
Blood 118 (22): e168-e179. 24 November 2011

Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression.
Ghani, S., Riemke, P., Schoenheit, J., Lenze, D., Stumm, J., Hoogenkamp, M., Lagendijk, A., Heinz, S., Bonifer, C., Bakkers, J., Abdelilah-Seyfried, S. ORCID: https://orcid.org/0000-0003-3183-3841, Hummel, M. and Rosenbauer, F. ORCID: https://orcid.org/0000-0001-7977-9421
Blood 118 (8): 2275-2284. 25 August 2011

The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed.
Popovic, J., Li, L.P., Kloetzel, P.M., Leisegang, M. ORCID: https://orcid.org/0000-0003-3692-7142, Uckert, W. and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Blood 118 (4): 946-954. 28 July 2011

Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs.
Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950, Mensen, A., Schradi, K., Gerlach, K., Wittstock, S., Winter, S. ORCID: https://orcid.org/0000-0002-4228-4537, Buechner, G., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Lipp, M. ORCID: https://orcid.org/0000-0002-0087-2672 and Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893
Blood 118 (4): 1020-1033. 28 July 2011

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL.
Hanash, A.M., Kappel, L.W., Yim, N.L., Nejat, R.A., Goldberg, G.L., Smith, O.M., Rao, U.K., Dykstra, L., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Holland, A.M., Dudakov, J.A., Liu, C., Murphy, G.F., Leonard, W.J., Heller, G. and van den Brink, M.R.M.
Blood 118 (2): 446-455. 14 July 2011

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.
Chan, G., Cheung, L.S., Yang, W., Milyavsky, M., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Gu, S., Hong, W.X., Liu, A.X., Wang, X., Barbara, M., Sharma, T., Gavin, J., Kutok, J.L., Iscove, N.N., Shannon, K.M., Dick, J.E., Neel, B.G. and Braun, B.S.
Blood 117 (16): 4253-4261. 21 April 2011

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.
Leddin, M., Perrod, C., Hoogenkamp, M., Ghani, S., Assi, S., Heinz, S., Wilson, N.K., Follows, G., Schoenheit, J., Vockentanz, L., Mosamam, A., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Tenen, D.G., Westhead, D.R., Goettgens, B., Bonifer, C. and Rosenbauer, F. ORCID: https://orcid.org/0000-0001-7977-9421
Blood 117 (10): 2827-2838. 10 March 2011

Epigenetic modification of the human CCR6 gene is associated with stable CCR6 expression in T cells.
Steinfelder, S. ORCID: https://orcid.org/0000-0002-8469-4251, Floess, S., Engelbert, D., Haeringer, B., Baron, U., Rivino, L., Steckel, B., Gruetzkau, A., Olek, S., Geginat, J., Huehn, J. and Hamann, A.
Blood 117 (10): 2839-2846. 10 March 2011

2010

I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development.
Orinska, Z., Foeger, N., Huber, M., Marschall, J., Mirghomizadeh, F., Du, X., Scheller, M., Rosenstiel, P., Goldmann, T., Bollinger, A., Beutler, B.A. and Bulfone-Paus, S.
Blood 116 (15): 2665-2675. 14 October 2010

Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo.
Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Markley, J.C., Tsai, J.J., Yim, N.L., Beattie, B.J., Klose, A.D., Holland, A.M., Ghosh, A., Rao, U.K., Stephan, M.T., Serganova, I., Santos, E.B., Brentjens, R.J., Blasberg, R.G., Sadelain, M. and van den Brink, M.R.M.
Blood 116 (11): e18-e25. 16 September 2010

CD11b is a therapy resistance- and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia.
Rhein, P., Mitlohner, R., Basso, G., Gaipa, G., Dworzak, M.N., Kirschner-Schwabe, R., Hagemeier, C., Stanulla, M., Schrappe, M., Ludwig, W.D., Karawajew, L. and Ratei, R.
Blood 115 (18): 3763-3771. 6 May 2010

2009

C/EBPβ regulates transcription factors critical for proliferation and survival of multiple myeloma cells.
Pal, R., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Galson, D.L., Gries, M., Li, S., Johrens, K., Anagnostopoulos, I., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Mapara, M.Y., Borghesi, L., Kardava, L., Roodman, G.D., Milcarek, C. and Lentzsch, S.
Blood 114 (18): 3890-3898. 29 October 2009

Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity.
Wilde, S., Sommermeyer, D., Frankenberger, B., Schiemann, M., Milosevic, S., Spranger, S., Pohla, H., Uckert, W., Busch, D.H. and Schendel, D.J.
Blood 114 (10): 2131-2139. 3 September 2009

Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells.
Vandendriessche, T., Ivics, Z. ORCID: https://orcid.org/0000-0002-7803-6658, Izsvak, Z. ORCID: https://orcid.org/0000-0002-2053-2384 and Chuah, M.K.
Blood 114 (8): 1461-1468. 20 August 2009

Stable gene transfer and expression in cord blood-derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system.
Xue, X., Huang, X., Nodland, S.E., Mates, L. ORCID: https://orcid.org/0000-0002-0058-470X, Ma, L., Izsvak, Z. ORCID: https://orcid.org/0000-0002-2053-2384, Ivics, Z. ORCID: https://orcid.org/0000-0002-7803-6658, Lebien, T.W., McIvor, R.S., Wagner, J.E. and Zhou, X.
Blood 114 (7): 1319-1330. 13 August 2009

Peripheral mural cell recruitment requires cell-autonomous heparan sulfate.
Stenzel, D., Nye, E., Nisancioglu, M., Adams, R.H., Yamaguchi, Y. and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Blood 114 (4): 915-924. 23 July 2009

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells.
Urbich, C., Rössig, L., Kaluza, D., Potente, M. ORCID: https://orcid.org/0000-0002-5689-0036, Boeckel, J.N., Knau, A., Diehl, F., Geng, J.G., Hofmann, W.K., Zeiher, A.M. and Dimmeler, S.
Blood 113 (22): 5669-5679. 28 May 2009

In vivo-activated CD103+ Foxp3+ Tregs: of men and mice.
Roetzschke, O., Borsellino, G., Battistini, L., Falk, K. and Kleinewietfeld, M. ORCID: https://orcid.org/0000-0002-2832-3149
Blood 113 (9): 2119-2120. 26 February 2009

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation.
Jenq, R.R., King, C.G., Volk, C., Suh, D., Smith, O.M., Rao, U.K., Yim, N.L., Holland, A.M., Lu, S.X., Zakrzewski, J.L., Goldberg, G.L., Diab, A., Alpdogan, O., Penack, O., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Kappel, L.W., Wolchok, J.D., Houghton, A.N., Perales, M.A. and van den Brink, M.R.M.
Blood 113 (7): 1574-1580. 12 February 2009

BK channels in innate immune functions of neutrophils and macrophages.
Essin, K., Gollasch, M. ORCID: https://orcid.org/0000-0003-2797-1934, Rolle, S. ORCID: https://orcid.org/0000-0002-1909-687X, Weissgerber, P., Sausbier, M., Bohn, E., Autenrieth, I.B., Ruth, P., Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199, Nauseef, W.M. and Kettritz, R. ORCID: https://orcid.org/0000-0001-5821-6718
Blood 113 (6): 1326-1331. 5 February 2009

CD49d provides access to 'untouched' human Foxp3+ Treg free of contaminating effector cells.
Kleinewietfeld, M. ORCID: https://orcid.org/0000-0002-2832-3149, Starke, M., Mitri, D.D., Borsellino, G., Battistini, L., Roetzschke, O. and Falk, K.
Blood 113 (4): 827-836. 22 January 2009

2008

Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3α.
Lamprecht, B., Kreher, S., Anagnostopoulos, I., Joehrens, K., Monteleone, G., Jundt, F., Stein, H., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413
Blood 112 (8): 3339-3347. 15 October 2008

Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses.
Groot, F., Welsch, S. and Sattentau, Q.J. ORCID: https://orcid.org/0000-0001-7170-1937
Blood 111 (9): 4660-3. 1 May 2008

The Y-box binding protein YB-1 is associated with progressive disease and mediates survival and drug resistance in multiple myeloma.
Chatterjee, M., Rancso, C., Stuehmer, T., Eckstein, N., Andrulis, M., Gerecke, C., Lorentz, H., Royer, H.D. and Bargou, R.C.
Blood 111 (7): 3714-3722. 1 April 2008

Hydrolysis of extracellular ATP by CD39+ Treg cells: context matters!
Kleinewietfeld, M. ORCID: https://orcid.org/0000-0002-2832-3149, Dimitri, D., Sternjak, A., Diamantini, A., Borsellino, G., Battistini, L., Roetzschke, O. and Falk, K.
Blood 111 (2): 965-966. 15 January 2008

Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.
Jeannet, G., Scheller, M., Scarpellino, L., Duboux, S., Gardiol, N., Back, J., Kuttler, F., Malanchi, I., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X, Huelsken, J. and Held, W.
Blood 111 (1): 142-149. 1 January 2008

2007

The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Loddenkemper, C., Rudolph, C., Schildhauer, I., Teichmann, B., Stein, H., Schlegelberger, B., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Blood 110 (8): 2996-3004. 15 October 2007

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.
Borsellino, G., Kleinewietfeld, M. ORCID: https://orcid.org/0000-0002-2832-3149, Di Mitri, D., Sternjak, A., Diamantini, A., Giometto, R., Hoepner, S., Centonze, D., Bernardi, G., Dell'Acqua, M.L., Rossini, P.M., Battistini, L., Roetzschke, O. and Falk, K.
Blood 110 (4): 1225-1232. 15 August 2007

NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils.
von Vietinghoff, S., Tunnemann, G. ORCID: https://orcid.org/0000-0001-6485-1136, Eulenberg, C. ORCID: https://orcid.org/0000-0002-2425-2275, Wellner, M., Cardoso, M.C., Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199 and Kettritz, R. ORCID: https://orcid.org/0000-0001-5821-6718
Blood 109 (10): 4487-4493. 15 May 2007

CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity.
Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Wengner, A.M. ORCID: https://orcid.org/0009-0009-5772-1945, Loddenkemper, C., Stein, H., Heimesaat, M.M., Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950 and Lipp, M. ORCID: https://orcid.org/0000-0002-0087-2672
Blood 109 (3): 886-895. 1 February 2007

STAT3 and MAPK signaling maintains overexpression of the heat shock proteins 90a and b in multiple myeloma cells, which critically contribute to tumor cell survival.
Chatterjee, M., Jain, S., Stuehmer, T., Andrulis, M., Ungethuem, U., Kuban, R.J., Lorentz, H., Bommert, K., Topp, M., Kramer, D., Mueller-Hermelink, H. K., Einsele, H., Greiner, A. and Bargou, R.C.
Blood 109 (2): 720-728. 15 January 2007

Active MAC-1 (CD11b/CD18) on DC is inhibitory for full T cell activation.
Varga, G., Balkow, S., Wild, M.K., Stadtbaeumer, A., Krummen, M., Rothoeft, T., Higuchi, T., Beissert, S., Wethmar, K., Scharffetter-Kochanek, K., Vestweber, D. and Grabbe, S.
Blood 109 (2): 661-669. 15 January 2007

Chemokines CCL19 and CCL21 promote activation-induced cell death of antigen-responding T cells.
Yasuda, T., Kuwabara, T., Nakano, H., Aritomi, K., Onodera, T., Lipp, M. ORCID: https://orcid.org/0000-0002-0087-2672, Takahama, Y. and Kakiuchi, T.
Blood 109 (2): 449-456. 15 January 2007

2006

Coordination between CCR7- and CCR9-mediated chemokine signals in pre-vascular fetal thymus colonization.
Liu, C., Saito, F., Liu, Z., Lei, Y., Uehara, S., Love, P., Lipp, M. ORCID: https://orcid.org/0000-0002-0087-2672, Kondo, S., Manley, N. and Takahama, Y.
Blood 108 (8): 2531-2539. 15 October 2006

Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma.
Martin-Subero, J.I., Wlodarska, I., Bastard, C., Picquenot, J.M., Hoeppner, J., Giefing, M., Klapper, W., Siebert, R., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Joos, S., Stein, H. and Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643
Blood 108 : 401-403. 1 July 2006

Lymphomas are sensitive to perforin-dependent cytotoxic pathways despite expression of PI-9 and overexpression of bcl-2.
Godal, R., Keilholz, U., Uharek, L., Letsch, A., Asemissen, A.M., Busse, A. ORCID: https://orcid.org/0000-0002-3470-6947, Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Thiel, E. and Scheibenbogen, C.
Blood 107 (8): 3205-3211. 15 April 2006

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells.
Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Hummel, M., Truss, M., Wollert-Wulf, B. ORCID: https://orcid.org/0009-0000-0257-4049, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Joehrens, K., Hagemeier, C., Bommert, K., Stein, H., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Bargou, R.C.
Blood 107 (6): 2536-2539. 15 March 2006

2005

Effect of transcription-factor concentrations on leukemic stem cells.
Rosenbauer, F. ORCID: https://orcid.org/0000-0001-7977-9421, Koschmieder, S., Steidl, U. and Tenen, D.G.
Blood 106 : 1519-1524. 1 September 2005

Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas.
Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Joehrens, K., Joos, S., Lietz, A., Hummel, F., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Jundt, F., Anagnostopoulos, I., Bommert, K., Lichter, P., Stein, H., Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129 and Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643
Blood 106 (13): 4287-4293. 25 August 2005

Non-genotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma.
Stuehmer, T., Chatterjee, M., Hildebrandt, M., Herrmann, P., Gollasch, H., Gerecke, C., Theurich, S., Cigliano, L., Manz, R.A., Daniel, P.T., Bommert, K., Vassilev, L.T. and Bargou, R.C.
Blood 106 : 3609-3617. 4 August 2005

Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene transduced human T cells.
Xue, S.A., Gao, L., Hart, D., Gillmore, R., Qasim, W., Thrasher, A., Apperley, J., Engels, B. ORCID: https://orcid.org/0000-0001-9682-2954, Uckert, W., Morris, E. and Stauss, H.J.
Blood 106 : 3062-3067. 14 July 2005

Expression of the chemokine receptors CXCR4, CXCR5, and CCR7 in primary central nervous system lymphoma.
Jahnke, K., Coupland, S.E., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Loddenkemper, C., Keilholz, U., Korfel, A., Stein, H., Thiel, E. and Scheibenbogen, C.
Blood 106 (1): 384-385. 1 July 2005

A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein beta and NF-kappaB activity in Hodgkin and anaplastic large cell lymphomas.
Jundt, F., Raetzel, N., Mueller, C., Calkhoven, C.F., Kley, K., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Lietz, A., Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X and Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643
Blood 106 : 1801-1807. 1 January 2005

CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T cell subset.
Kleinewietfeld, M. ORCID: https://orcid.org/0000-0002-2832-3149, Puentes, F., Borsellino, G., Battistini, L., Roetzschke, O. and Falk, K.
Blood 105 (7): 2877-2886. 1 January 2005

Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis.
Koh, K.R., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Mapara, M.Y., Lemke, B., Stirling, D., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Zenke, M. and Lentzsch, S.
Blood 105 (10): 3833-3840. 1 January 2005

Role of CCL21 in recruitment of T precursor cells to fetal thymus.
Liu, C., Ueno, T., Kuse, S., Saito, F., Nitta, T., Piali, L., Nakano, H., Kakiuchi, T., Lipp, M. ORCID: https://orcid.org/0000-0002-0087-2672, Hollander, G.A. and Takahama, Y.
Blood 105 (1): 31-39. 1 January 2005

2004

pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1.
Rosenbauer, F. ORCID: https://orcid.org/0000-0001-7977-9421, Wagner, K., Zhang, P., Knobeloch, K.P., Iwama, A. and Tenen, D.G.
Blood 103 : 4294-4301. 1 June 2004

Graft-versus-host-reactive donor CD4 cells can induce T cell-mediated rejection of the donor marrow in mixed allogeneic chimeras prepared with nonmyeloablative conditioning.
Kim, Y.M., Mapara, M.Y., Down, J.D., Johnson, K.W., Boisgerault, F., Akiyama, Y., Benichou, G., Pelot, M., Zhao, G. and Sykes, M.
Blood 103 : 732-739. 15 January 2004

Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells.
Chatterjee, M., Stuehmer, T., Herrmann, P., Bommert, K., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Bargou, R.C.
Blood 104 (12): 3712-3721. 1 January 2004

Jagged1-induced notch signaling drives proliferation of multiple myeloma cells.
Jundt, F., Schulze-Proebsting, K., Anagnostopoulos, I., Muehlinghaus, G., Chatterjee, M., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Bargou, R.C., Manz, R., Stein, H. and Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643
Blood 103 (9): 3511-3515. 1 January 2004

Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation induces a CD8+ T cell-mediated graft-versus-tumor effect that is independent of the recognition of alloantigenic tumor targets.
Stelljes, M., Strothotte, R., Pauels, H.G., Poremba, C., Milse, M., Specht, C., Albring, J., Bisping, G., Scheffold, C., Kammertoens, T. ORCID: https://orcid.org/0000-0003-3309-5141, Oelmann, E., Silling, G., Berdel, W.E. and Kienast, J.
Blood 104 (4): 1210-1216. 1 January 2004

Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors.
van den Akker, E., van Dijk, T., Parren-van Amelsvoort, M., Grossmann, K.S., Schaeper, U., Toney-Earley, K., Waltz, S.E., Loewenberg, B. and von Lindern, M.
Blood 103 (12): 4457-4465. 1 January 2004

2003

Monocyte-expressed urokinase inhibits vascular smooth muscle cell growth by activating Stat1.
Kunigal, S., Kusch, A. ORCID: https://orcid.org/0000-0002-6666-7081, Tkachuk, N., Tkachuk, S., Jerke, U., Haller, H. and Dumler, I.
Blood 102 (13): 4377-4383. 15 December 2003

Inhibition of NF-κ B by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis.
Choi, M. ORCID: https://orcid.org/0000-0002-0286-1491, Rolle, S. ORCID: https://orcid.org/0000-0002-1909-687X, Wellner, M., Cardoso, M.C. ORCID: https://orcid.org/0000-0001-8427-8859, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199 and Kettritz, R. ORCID: https://orcid.org/0000-0001-5821-6718
Blood 102 (6): 2259-2267. 15 September 2003

Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: critical role for recipient-derived IFN-gamma.
Rubio, M.T., Kim, Y.M., Sachs, T., Mapara, M., Zhao, G. and Sykes, M.
Blood 102 : 2300-2307. 15 September 2003

Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis.
Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Lietz, A., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Hinz, M. ORCID: https://orcid.org/0000-0003-2611-4121, Jundt, F., Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Bommert, K. and Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643
Blood 102 (3): 1028-1034. 1 August 2003

Macrophage inflammatory protein 1-alpha (MIP-1alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.
Lentzsch, S., Gries, M., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Bargou, R., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Mapara, M.Y.
Blood 101 (9): 3568-3573. 1 May 2003

Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma.
Smith, J.R., Braziel, R.M., Paoletti, S., Lipp, M. ORCID: https://orcid.org/0000-0002-0087-2672, Uguccioni, M. and Rosenbaum, J.T.
Blood 101 (3): 815-821. 1 February 2003

2002

In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp 130/STAT3 pathway.
Chatterjee, M., Hoenemann, D., Lentzsch, S., Bommert, K., Sers, C., Herrmann, P., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Bargou, R.C.
Blood 100 (9): 3311-3318. 1 November 2002

Homozygosity mapping of a second gene locus for hereditary combined deficiency of vitamin K-dependent clotting factors to the centromeric region of chromosome 16.
Fregin, A., Rost, S., Wolz, W., Krebsova, A., Muller, C.R. and Oldenburg, J.
Blood 100 (9): 3229-3232. 1 November 2002

Generalized crystal-storing histiocytosis associated with monoclonal gammopathy: molecular analysis of a disorder with rapid clinical course and review of the literature.
Lebeau, A., Zeindl-Eberhart, E., Mueller, E.C., Mueller-Hoecker, J., Jungblut, P.R., Emmerich, B. and Loehrs, U.
Blood 100 (5): 1817-1827. 1 September 2002

Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells.
Mapara, M.Y., Kim, Y.M., Wang, S.P., Bronson, R., Sachs, D.H. and Sykes, M.
Blood 100 : 1903-1909. 1 September 2002

In vitro susceptibility to dexamethasone- and doxorubicin-induced apoptotic cell death in context of maturation stage, responsiveness to interleukin 7, and early cytoreduction in vivo in childhood T-cell acute lymphoblastic leukemia.
Wuchter, C., Ruppert, V., Schrappe, M., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Ludwig, W.D. and Karawajew, L.
Blood 99 (11): 4109-4115. 1 June 2002

Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.
Jundt, F., Anagnostopoulos, I., Foerster, R., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Stein, H. and Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643
Blood 99 (9): 3398-3403. 1 May 2002

Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease.
Jundt, F., Kley, K., Anagnostopoulos, I., Schulze-Proebsting, K., Greiner, A., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Wirth, T., Stein, H. and Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643
Blood 99 (8): 3060-3062. 15 April 2002

Human hematopoiesis in murine embryos after injecting human cord blood-derived hematopoietic stem cells into murine blastocysts.
Harder, F., Henschler, R., Junghahn, I., Lamers, M.C. and Mueller, A.M.
Blood 99 (2): 719-721. 15 January 2002

Up-regulation of the chemokine receptor CCR7 in classical but not in lymphocyte-predominant Hodgkin disease correlates with distinct dissemination of neoplastic cells in lymphoid organs.
Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Foss, H.D., Meyer, D., Hinz, M., Leder, K., Stein, H. and Lipp, M.
Blood 99 (4): 1109-1116. 1 January 2002

2001

Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration.
Podar, K., Tai, Y.T., Davies, F.E., Lentzsch, S., Sattler, M., Hideshima, T., Lin, B.K., Gupta, D., Shima, Y., Chauhan, D., Mitsiades, C., Raje, N., Richardson, P. and Anderson, K.C.
Blood 98 (2): 428-435. 15 July 2001

Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma.
Davies, F.E., Raje, N., Hideshima, T., Lentzsch, S., Young, G., Tai, Y.T., Lin, B., Podar, K., Gupta, D., Chauhan, D., Treon, S.P., Richardson, P.G., Schlossman, R.L., Morgan, G.J., Muller, G.W., Stirling, D.I. and Anderson, K.C.
Blood 98 (1): 210-216. 1 July 2001

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.
Wieder, T., Essmann, F., Prokop, A., Schmelz, K., Schulze-Osthoff, K., Beyaert, R., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Daniel, P.T.
Blood 97 (5): 1378-1387. 1 March 2001

Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.
Hinz, M. ORCID: https://orcid.org/0000-0003-2611-4121, Loeser, P., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Krappmann, D. ORCID: https://orcid.org/0000-0001-7640-3234, Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
Blood 97 (9): 2798-2807. 1 January 2001

The leucine zipper region of Myb oncoprotein regulates the commitment of hematopoietic progenitors.
Karafiat, V., Dvorakova, M., Pajer, P., Kralova, J., Horejsi, Z., Cermak, V., Bartunek, P., Zenke, M. and Dvorak, M.
Blood 98 (13): 3668-3676. 1 January 2001

2000

Donor stromal cells from human blood engraft in NOD/SCID mice.
Goan, S.R., Junghahn, I., Wissler, M., Becker, M., Aumann, J., Just, U., Martiny-Baron, G., Fichtner, I. and Henschler, R.
Blood 96 : 3971-3978. 1 December 2000

Inhibition of in vitro spontaneous apoptosis by IL-7 correlates with Bcl-2 up-regulation, cortical/mature immunophenotype, and better early cytoreduction of childhood T-cell acute lymphoblastic leukemia.
Karawajew, L., Ruppert, V., Wuchter, C., Koesser, A., Schrappe, M., Doerken, B. and Ludwig, W.D.
Blood 96 : 297-306. 1 July 2000

Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group.
Schrappe, M., Reiter, A., Ludwig, W.D., Harbott, J., Zimmermann, M., Hiddemann, W., Niemeyer, C., Henze, G., Feldges, A., Zintl, F., Kornhuber, B., Ritter, J., Welte, K., Gadner, H. and Riehm, H.
Blood 95 (11): 3310-3322. 1 June 2000

Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6.
Van Brocklyn, J.R., Graeler, M.H., Bernhardt, G., Hobson, J.P., Lipp, M. and Spiegel, S.
Blood 95 : 2624-2629. 15 April 2000

Intensive ALL-type therapy without local radiotherapy provides a 90% event-free survival for children with T-cell lymphoblastic lymphoma: a BFM group report.
Reiter, A., Schrappe, M., Ludwig, W.D., Tiemann, M., Parwaresch, R., Zimmermann, M., Schirg, E., Henze, G., Schellong, G., Gadner, H. and Riehm, H.
Blood 95 : 416-421. 15 January 2000

A recombinant bispecific single-chain antibody, CD19 X CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes.
Loeffler, A., Kufer, P., Lutterbuese, R., Zettl, F., Daniel, P.T., Schwenkenbecher, J.M., Riethmueller, G., Doerken, B. and Bargou, R.C.
Blood 95 : 2098-2103. 1 January 2000

1999

Improved treatment results in childhood B-cell neoplasms with tailored intensification of therapy: a report of the Berlin-Frankfurt-Muenster group trial NHL-BFM 90.
Reiter, A., Schrappe, M., Tiemann, M., Ludwig, W.D., Yakisan, E., Zimmermann, M., Mann, G., Chott, A., Ebell, W., Klingebiel, T., Graf, N., Kremens, B., Mueller-Weihrich, S., Pluess, H.J., Zintl, F., Henze, G. and Riehm, H.
Blood 94 : 3294-3306. 15 November 1999

Overexpression of IkappaBalpha without inhibition of NF-kappaB activity and mutations in the IkappaBalpha gene in Reed-Sternberg cells.
Emmerich, F., Meiser, M., Hummel, M., Demel, G., Foss, H.D., Jundt, F., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Krappmann, D. ORCID: https://orcid.org/0000-0001-7640-3234, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Stein, H. and Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643
Blood 94 : 3129-3134. 1 November 1999

Hodgkin/Reed-Sternberg cells induce fibroblasts to secrete eotaxin, a potent chemoattractant for T cells and eosinophils.
Jundt, F., Anagnostopoulos, I., Bommert, K., Emmerich, F., Mueller, G., Foss, H.D., Royer, H.D., Stein, H. and Doerken, B.
Blood 94 : 2065-2071. 15 September 1999

Prednisone response is the strongest predictor of treatment outcome in infant acute lymphoblastic leukemia.
Doerdelmann, M., Reiter, A., Borkhardt, A., Ludwig, W.D., Goetz, N., Viehmann, S., Gadner, H., Riehm, H. and Schrappe, M.
Blood 94 (4): 1209-1217. 15 August 1999

Expression of the death gene Bik/Nbk promotes sensitivity to drug-induced apoptosis in corticosteroid-resistant T-cell lymphoma and prevents tumor growth in severe combined immunodeficient mice.
Daniel, P.T., Pun, K.T., Ritschel, S., Sturm, I., Holler, J., Doerken, B. and Brown, R.
Blood 94 : 1100-1107. 1 August 1999

Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the german AML cooperative group.
Buechner, T., Hiddemann, W., Woermann, B., Loeffler, H., Gassmann, W., Haferlach, T., Fonatsch, C., Haase, D., Schoch, C., Hossfeld, D., Lengfelder, E., Aul, C., Heyll, A., Maschmeyer, G., Ludwig, W.D., Sauerland, M.C. and Heinecke, A.
Blood 93 : 4116-4124. 15 June 1999

Aerosolized amphotericin B inhalations as prophylaxis of invasive aspergillus infections during prolonged neutropenia: results of a prospective randomized multicenter trial.
Schwartz, S., Behre, G., Heinemann, V., Wandt, H., Schilling, E., Arning, M., Trittin, A., Kern, W.V., Boenisch, O., Bosse, D., Lenz, K., Ludwig, W.D., Hiddemann, W., Siegert, W. and Beyer, J.
Blood 93 (11): 3654-3661. 1 June 1999

1998

Immunotherapy of B-cell lymphoma with CD3x19 bispecific antibodies: costimulation via CD28 prevents "Veto" apoptosis of antibody-targeted cytotoxic T cells.
Daniel, P.T., Kroidl, A., Kopp, J., Sturm, I., Moldenhauer, G., Doerken, B. and Pezzutto, A.
Blood 92 (12): 4750-4757. 15 December 1998

Deletions in the long arm of chromosome 10 in lymphomas with t(14;18): A pathogenetic role of the tumor suppressor genes PTEN/MMAC1 and MXI1?
Siebert, R., Gesk, S., Harder, S., Ploetz, S., Matthiesen, P., Grote, W., Schlegelberger, B., Jandrig, B., Grasmo-Wendler, U.H., Scherneck, S., Rosenwald, A. and Ott, G.
Blood 92 (11): 4487-4489. 1 December 1998

Growth and differentiation of human stem cell factor/erythropoietin-dependent erythroid progenitor cells in vitro.
Panzenboeck, B., Bartunek, P., Mapara, M.Y. and Zenke, M.
Blood 92 (10): 3658-3668. 15 November 1998

Immunophenotypic and genotypic features, clinical characteristics, and treatment outcome of adult pro-B acute lymphoblastic leukemia: Results of the German multicenter trials GMALL 03/87 and 04/89.
Ludwig, W.D., Rieder, H., Bartram, C.R., Heinze, B., Schwartz, S., Gassmann, W., Loeffler, H., Hossfeld, D., Heil, G., Handt, S., Heyll, A., Diedrich, H., Fischer, K., Weiss, A., Voelkers, B., Aydemir, U., Fonatsch, C., Goekbuget, N., Thiel, E. and Hoelzer, D.
Blood 92 (6): 1898-1909. 15 September 1998

The reliability and specificity of c-kit for the diagnosis of acute myeloid leukemias and undifferentiated leukemias.
Bene, M.C., Bernier, M., Casasnovas, R.O., Castoldi, G., Knapp, W., Lanza, F., Ludwig, W.D., Matutes, E., Orfao, A., Sperling, C. and van't Veer, M.B.
Blood 92 (2): 596-599. 15 July 1998

MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11): both rearrangements are associated with a poor prognosis.
Dreyling, M.H., Schrader, K., Fonatsch, C., Schlegelberger, B., Haase, D., Schoch, C., Ludwig, W.D., Loeffler, H., Buechner, T., Wormann, B., Hiddemann, W. and Bohlander, S.K.
Blood 91 (12): 4662-4667. 15 June 1998

CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia.
Beltinger, C., Kurz, E., Boehler, T., Schrappe, M., Ludwig, W.D. and Debatin, K.M.
Blood 91 (10): 3943-3951. 15 May 1998