2026
High-affinity human germline and mutated autoantibodies commonly cross-react to self-antigens in 5 subgroups of autoimmune encephalitis.
Stöffler, Laura, Kreye, Jakob, Arlt, Friederike A., Sanchez-Sendin, Elisa, Hoffmann, Julius, Kornau, Hans-Christian, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, van Hoof, Scott, Wernick, Stephanie, Homeyer, Marie, Reincke, Sebastian Momsen
ORCID: https://orcid.org/0000-0002-8132-3527 and Prüss, Harald
Neurology Neuroimmunology & Neuroinflammation 13
(4): e200608.
July 2026
Septin multimer autoantibodies in severe motor neuropathy mimicking lower motor neuron disease.
Arlt, Friederike A., Miske, Ramona, Appeltshauser, Luise, Zinnow, Viktoria, Borowski, Kathrin, Stenzel, Werner, Radbruch, Helena, Meisel, Andreas, Ruprecht, Klemens, Endres, Matthias, Blau, Igor, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Sanchez-Sendin, Elisa, Wernick, Stephanie, Pressler, Hannah, Stascheit, Frauke, Linke, Janis, Hümmert, Sophie, Werner, Hauke B., Wibisono, Esravila A., Doppler, Kathrin, Komorowski, Lars, Spiliotis, Elias T., Dubey, Divyanshu, Zeckeridou, Anastasia, Pittock, Sean J., Mills, John R., McKeon, Andrew, Scharf, Madeleine and Prüss, Harald
Brain
: awag183.
8 June 2026
(In Press)
The histone modifier KANSL2 is an actionable biomarker in multiple myeloma.
Jiang, Kaiting
ORCID: https://orcid.org/0009-0000-3282-5953, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Herzberg, Frederik
ORCID: https://orcid.org/0009-0000-7338-7849, Zhao, Yan
ORCID: https://orcid.org/0000-0002-3087-4767, Gasper, Amelie
ORCID: https://orcid.org/0009-0003-5247-9498, Baumgartner, Francis
ORCID: https://orcid.org/0000-0003-0768-1956, Jung, Paul
ORCID: https://orcid.org/0000-0002-6447-450X, Braune, Jan
ORCID: https://orcid.org/0000-0003-2026-2641, Schulze, Veronika
ORCID: https://orcid.org/0009-0004-0823-1660, Isaakidis, Konstandina
ORCID: https://orcid.org/0009-0002-7451-6889, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Krönke, Jan
ORCID: https://orcid.org/0000-0002-4649-0506, Wirth, Matthias
ORCID: https://orcid.org/0000-0002-8340-0872, Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958 and Habringer, Stefan
ORCID: https://orcid.org/0000-0002-3976-9592
Molecular Cancer Therapeutics 25
(6): 1016-1029.
1 June 2026
Consensus statement on mass spectrometry-based proteomic analysis of cardiac tissue.
Lundby, Alicia
ORCID: https://orcid.org/0000-0002-1612-6041, Van Eyk, Jennifer E.
ORCID: https://orcid.org/0000-0001-9050-148X, Mayr, Manuel
ORCID: https://orcid.org/0000-0002-0597-829X, White, Melanie Y.
ORCID: https://orcid.org/0000-0003-2571-2816, Kirk, Jonathan A., Achter, Jonathan S.
ORCID: https://orcid.org/0000-0002-1587-622X, Fert-Bober, Justyna, Wierer, Michael
ORCID: https://orcid.org/0000-0002-0356-5571, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Lam, Maggie P.Y., Humphrey, Sean J.
ORCID: https://orcid.org/0000-0002-2666-9744, Lau, Edward, Gramolini, Anthony O.
ORCID: https://orcid.org/0000-0003-1109-2070, Ge, Ying
ORCID: https://orcid.org/0000-0001-5211-6812 and Gundry, Rebekah L.
ORCID: https://orcid.org/0000-0002-9263-833X
Nature Cardiovascular Research 5
(6): 526-540.
June 2026
Distinct roles for MNK1 and MNK2 in social and cognitive behavior through kinase-specific regulation of the synaptic proteome and phosphoproteome.
Proce, Rosalba Olga, Steinecker, Maria, Giacomelli, Chiara
ORCID: https://orcid.org/0000-0003-1466-1371, Uddström, Erika
ORCID: https://orcid.org/0009-0009-5298-480X, Chatterjee, Anirban
ORCID: https://orcid.org/0009-0002-8271-384X, Wüsthoff, Souhaila
ORCID: https://orcid.org/0000-0001-7653-3565, Teixeira Alves, Luiz Gustavo
ORCID: https://orcid.org/0000-0002-5822-4168, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Pohl, Tobias
ORCID: https://orcid.org/0000-0001-8698-8475, Maxwell, Katie, Hortmann, Lucie, Kunz, Severine
ORCID: https://orcid.org/0000-0002-0131-3506, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Landthaler, Markus
ORCID: https://orcid.org/0000-0002-1075-8734, Bunina, Daria
ORCID: https://orcid.org/0000-0002-5885-7440 and Hörnberg, Hanna
ORCID: https://orcid.org/0000-0001-9142-1932
Molecular Psychiatry 31
(6): 3446-3461.
June 2026
Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome.
Koprulu, Mine, Smith-Byrne, Karl, Ferolito, Brian Richard, Macdonald-Dunlop, Erin, Luan, Jian'an, Hedman, Åsa K., Ogamba, Chibuzor Franklin, Kuliesius, Jurgis, Repetto, Linda, Ramisch, Anna, Abbasi, Fahim, Ärnlöv, Johan, Assimes, Themistocles L., Björck, Hanna M., Björkander, Sophia, Böttcher, Morten, Butterworth, Adam Stuart, Chen, Zhengming, Cho, Kelly, Clarke, Robert Joseph, Cox, Simon Riddington, Czene, Kamila, Danesh, John, Dedoussis, George, Elmståhl, Sölve, Eriksson, Niclas, Eriksson, Per, Esko, Tõnu, Ferreiro-Iglesias, Aida, Franks, Paul William, Fu, Jingyuan, Gaziano, J Michael, Ghanbari, Mohsen, Gieger, Christian, Gilly, Arthur, Grallert, Harald, Gunter, Marc James, Gustafsson, Stefan, Göteson, Andreas, Hall, Per Frans Leonard, Hansson, Oskar, Harris, Sarah Elizabeth, Hayward, Caroline, Herder, Christian, Hernandez-Pacheco, Natalia, Hijazi, Ziad, Hillary, Robert F., Hopewell, Jemma Caroline, Hu, Shixian, Hwang, Shih-Jen, Jern, Christina, Johansson, Åsa, Jonsson, Lina, Kalnapenkis, Anette, Kerrison, Nicola Dorothy, Kho, Pik Fang, Klaric, Lucija, Kohleick, Leonhard, Kraft, Julia, Landén, Mikael, Levy, Daniel, Li, Liming, Lind, Lars, Long, Jirong, Mattsson-Carlgren, Niklas, Melén, Erik, Merid, Simon Kebede, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Michaëlsson, Karl, Møller, Peter Loof, Murgia, Federico, Nyegaard, Mette, Park, Young-Chan, Pearson, Ewan, Peters, James, Petrie, John Ross, Png, Grace, Polašek, Ozren, Prins, Bram Peter, Ripke, Stephan, Roden, Michael, Rohde, Palle Duun, Said, Saredo, Shen, Xia, Schwenk, Jochen M., Siegbahn, Agneta, Smith, J. Gustav, Stanne, Tara M, Suhre, Karsten, Sundström, Johan, Thorand, Barbara, Valdes-Marquez, Elsa, Vallerga, Costanza L., van Meurs, Joyce B.J., Viñuela, Ana, Võsa, Urmo, Wallentin, Lars, Walters, Robin G., Wareham, Nicholas John, Weber, Joachim Eduard, Weersma, Rinse Karel, Wilson, James F., Winther, Simon, Yasmeen, Summaira, Zanetti, Daniela, Zeggini, Eleftheria, Zhao, Jing Hua, Zhernakova, Alexandra, Zhernakova, Daria V., Ziehm, Matthias
ORCID: https://orcid.org/0000-0001-7074-4054, Kessler, Benedikt Mathias, Pereira, Alexandre C., Mälarstig, Anders, Pietzner, Maik and Langenberg, Claudia
Cell 189
(11): 3339-3357.e11.
28 May 2026
Systemic effects of cystic fibrosis transmembrane conductance regulator modulators on the plasma and serum proteome.
Fentker, Kerstin
ORCID: https://orcid.org/0009-0005-0437-1049, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Ziehm, Matthias
ORCID: https://orcid.org/0000-0001-7074-4054, Niquet, Sylvia, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Duerr, Julia, Schaupp, Laura, Roehmel, Jobst, Thee, Stephanie, Hämmerling, Susanne, Sommerburg, Olaf, Stahl, Mirjam, Graeber, Simon Y., Mall, Marcus A. and Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X
Cell Systems 17
: 101569.
20 May 2026
Endothelial YAP/TAZ rewiring under cardiometabolic stress drives sex-divergent vascular remodeling in heart failure with preserved ejection fraction.
Klaus-Bergmann, Alexandra
ORCID: https://orcid.org/0000-0002-1164-3322, Sievers, Laura Katharina, Versnjak, Jakob, Koch, Katharina, Nawara, Tomasz
ORCID: https://orcid.org/0000-0002-4801-4095, Bartels-Klein, Eireen, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Weiner 3rd, January
ORCID: https://orcid.org/0000-0003-1438-7819, Meier, Katja, Hollfinger, Irene
ORCID: https://orcid.org/0000-0002-6233-8395, Kamer, Ilona, Taube, Martin, Heuser, Arnd
ORCID: https://orcid.org/0000-0002-3334-960X, Borodina, Tatiana
ORCID: https://orcid.org/0000-0002-6978-016X, Beule, Dieter
ORCID: https://orcid.org/0000-0002-3284-0632, Potente, Michael
ORCID: https://orcid.org/0000-0002-5689-0036, Landmesser, Ulf
ORCID: https://orcid.org/0000-0002-0214-3203, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Kelm, Marcus, Muller, Dominik N.
ORCID: https://orcid.org/0000-0003-3650-5644 and Gerhardt, Holger
ORCID: https://orcid.org/0000-0002-3030-0384
bioRxiv
: 2026.05.07.723127.
13 May 2026
Identification of MHC ligands through allele-guided isolation combined with machine learning for improved MHC assignment using ARDisplay-I.
Mecklenbräuker, Shima, Skoczylas, Piotr, Biernat, Paweł
ORCID: https://orcid.org/0000-0003-1482-9621, Zaghla, Badeel K.H.Q.
ORCID: https://orcid.org/0009-0002-2675-8859, Atay, Bilge
ORCID: https://orcid.org/0009-0008-6968-8858, Hossam, Mai, Król-Józaga, Bartłomiej
ORCID: https://orcid.org/0000-0003-2526-0629, Jasiński, Maciej
ORCID: https://orcid.org/0000-0001-6467-2752, Pienkowski, Victor Murcia
ORCID: https://orcid.org/0000-0002-1383-8019, Sanecka-Duin, Anna
ORCID: https://orcid.org/0000-0001-7684-2149, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Haji, Mohamed, Szatanek, Rafał, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Kaczmarczyk, Jan
ORCID: https://orcid.org/0000-0002-1629-3675, Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958, Blum, Agnieszka and Klatt, Martin G.
ORCID: https://orcid.org/0000-0001-8703-7305
Molecular & Cellular Proteomics 25
(5): 101560.
May 2026
Integrated left ventricular multi-omics landscape of human cardiometabolic HFpEF.
Capone, Federico
ORCID: https://orcid.org/0000-0001-8127-5564, Rommel, Karl-Philipp, Forbes, Martin
ORCID: https://orcid.org/0000-0001-7775-8352, Fahjen, Pauline
ORCID: https://orcid.org/0000-0002-5015-0643, Strocchi, Stefano
ORCID: https://orcid.org/0009-0002-8879-6156, Rosch, Sebastian, Wang, Rongling
ORCID: https://orcid.org/0000-0001-8719-938X, Bode, David, Nambiar, Natasha
ORCID: https://orcid.org/0009-0004-3538-8081, Eroglu, Tolga
ORCID: https://orcid.org/0000-0003-3404-2754, Santiago-Padilla, Leandro
ORCID: https://orcid.org/0000-0002-0873-7205, Morieri, Mario Luca, Liu, Luo, Farrelly, Catherine, Vacca, Antonio
ORCID: https://orcid.org/0000-0003-0051-7723, Mastrobuoni, Guido
ORCID: https://orcid.org/0000-0003-4509-1295, Jung, Simone, Diezel, Saskia A., Liévano Contreras, Sarah V., Hübner, Norbert
ORCID: https://orcid.org/0000-0002-1218-6223, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Kempa, Stefan
ORCID: https://orcid.org/0000-0002-0696-9299, Lurz, Philipp and Schiattarella, Gabriele G.
ORCID: https://orcid.org/0000-0002-7582-7171
Cardiovascular Research 122
(8): 984-1000.
May 2026
Autophagy selectively clears ER in TNF-α-induced muscle atrophy.
Dueren, Ursula K.
ORCID: https://orcid.org/0009-0006-4407-9031, Wei, Alan An Jung
ORCID: https://orcid.org/0000-0003-4255-9470, Gressler, A. Elisabeth
ORCID: https://orcid.org/0000-0003-3229-1554, Rapp, Simon
ORCID: https://orcid.org/0000-0002-5141-0611, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Kerridge, Robert, Buonomo, Viviana, Viviana, Paolo
ORCID: https://orcid.org/0000-0002-9942-9389, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Selbach, Matthias
ORCID: https://orcid.org/0000-0003-2454-8751, Simon, Anna Katharina
ORCID: https://orcid.org/0000-0002-4077-7995 and Sommer, Thomas
ORCID: https://orcid.org/0000-0001-9990-5202
Autophagy Reports 5
(1): 2649064.
14 April 2026
Systemic effects of cystic fibrosis transmembrane conductance regulator (CFTR) modulators on the plasma and serum proteome.
Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X and Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X
[Dataset]
14 April 2026
Additional file 3 of BRAFV600E patient derived colon cancer organoids identify biomarkers of response to EGFR and BRAF inhibition and replicate clinical data.
Kotarac, Anna, Osumi, Hiroki, Malt, Alexander
ORCID: https://orcid.org/0009-0005-4049-0846, Alp, Keziban Merve
ORCID: https://orcid.org/0000-0001-9919-9838, Jarosch, Armin, Werner, Johannes, Benary, Manuela
ORCID: https://orcid.org/0000-0002-3067-2030, Neumann, Christopher C.M., Yao, Ryoji, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Eils, Roland, Beule, Dieter
ORCID: https://orcid.org/0000-0002-3284-0632, Sers, Christine, Keilholz, Ulrich, Ishaque, Naveed
ORCID: https://orcid.org/0000-0002-8426-901X, Stintzing, Sebastian and Vecchione, Loredana
[Dataset]
10 April 2026
BRAF(V600E) patient derived colon cancer organoids identify biomarkers of response to EGFR and BRAF inhibition and replicate clinical data.
Kotarac, Anna, Osumi, Hiroki, Malt, Alexander
ORCID: https://orcid.org/0009-0005-4049-0846, Alp, Keziban Merve
ORCID: https://orcid.org/0000-0001-9919-9838, Jarosch, Armin, Werner, Johannes, Benary, Manuela
ORCID: https://orcid.org/0000-0002-3067-2030, Neumann, Christopher C.M., Yao, Ryoji, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Eils, Roland, Beule, Dieter
ORCID: https://orcid.org/0000-0002-3284-0632, Sers, Christine, Keilholz, Ulrich, Ishaque, Naveed
ORCID: https://orcid.org/0000-0002-8426-901X, Stintzing, Sebastian and Vecchione, Loredana
Journal of Experimental & Clinical Cancer Research 45
(1): 92.
9 April 2026
HAP40 functions as a proteostasis regulator by controlling huntingtin interactions and its release into the extracellular space.
Silva Ramos, Eduardo
ORCID: https://orcid.org/0000-0002-8520-9107, Boeddrich, Annett
ORCID: https://orcid.org/0000-0001-9118-050X, Haenig, Christian
ORCID: https://orcid.org/0000-0003-1973-7646, Trepte, Philipp
ORCID: https://orcid.org/0000-0002-8141-6272, Ammar, Orchid
ORCID: https://orcid.org/0009-0003-5341-4434, Secker, Christopher
ORCID: https://orcid.org/0000-0002-7222-536X, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Ivanov, Andranik
ORCID: https://orcid.org/0000-0002-4824-1925, Keith, Brandon, Harding, Rachel J.
ORCID: https://orcid.org/0000-0002-1134-391X, Schindler, Franziska
ORCID: https://orcid.org/0000-0002-3320-8284, Koudelka, Tomas
ORCID: https://orcid.org/0009-0008-2895-6051, Roth, Leonard, Scharek, Nadine, Zenkner, Martina, Neuendorf, Nancy, Golusik, Sabrina, Beetz, Stephanie, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Piazza, Ilaria
ORCID: https://orcid.org/0000-0001-5895-6134, Schnoegl, Sigrid and Wanker, Erich E.
ORCID: https://orcid.org/0000-0001-8072-1630
bioRxiv
: 2026.03.31.715351.
1 April 2026
Aberrant SUMOylation restricts the targetable cancer immunopeptidome.
Demel, Uta M.
ORCID: https://orcid.org/0000-0002-6480-4185, Meurer, Anna, Zaghla, Badeel Kh Q., Atay, Bilge, Steiert, Daniel, Hummel, Luca V., Isaakidis, Konstandina, Zang, Chuanbing, Korenkov, Michael
ORCID: https://orcid.org/0000-0002-2988-8483, Schielin, Marlon, Yousefian, Schayan
ORCID: https://orcid.org/0000-0003-0902-0369, Mecklenbräuker, Shima, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Haas, Simon
ORCID: https://orcid.org/0000-0001-9227-2051, Busse, Antonia
ORCID: https://orcid.org/0000-0002-3470-6947, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Müller, Stefan, Wirth, Matthias
ORCID: https://orcid.org/0000-0002-8340-0872, Klatt, Martin G. and Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958
Advanced Science 13
(17): e11449.
23 March 2026
Resource data for: Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome.
Boehm, Volker
ORCID: https://orcid.org/0000-0001-7588-9842, Wallmeroth, Damaris
ORCID: https://orcid.org/0000-0003-3437-4070, Wulf, Paul
ORCID: https://orcid.org/0009-0002-6356-2361, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Teixeira Alves, Luiz Gustavo
ORCID: https://orcid.org/0000-0002-5822-4168, Reinecke, Lucie
ORCID: https://orcid.org/0009-0003-7083-0923, Riedel, Maximilian
ORCID: https://orcid.org/0009-0002-9817-3083, Wyler, Emanuel
ORCID: https://orcid.org/0000-0002-9884-1806, Franitza, Marek, Becker, Kerstin
ORCID: https://orcid.org/0009-0009-7897-7181, Polkovnychenko, Karina, Del Giudice, Simone
ORCID: https://orcid.org/0000-0003-0194-3767, Benlasfer, Nouhad, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Landthaler, Markus
ORCID: https://orcid.org/0000-0002-1075-8734 and Gehring, Niels H.
ORCID: https://orcid.org/0000-0001-7792-1164
[Dataset]
18 March 2026
The histone modifier KANSL2 is an actionable biomarker for response to epigenetic modifiers in multiple myeloma.
Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X and Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X
[Dataset]
22 February 2026
Time‑resolved multi-omic analysis of paclitaxel exposure in human iPSC‑derived sensory neurons unveils mechanisms of chemotherapy‑induced peripheral neuropathy.
Schinke, Christian
ORCID: https://orcid.org/0000-0003-0199-9672, Maierhof, Smilla K., Hew, Lois
ORCID: https://orcid.org/0000-0002-0183-8177, Fernandez Vallone, Valeria, Frahm, Silke
ORCID: https://orcid.org/0000-0001-5645-2557, Telugu, Narasimha Swamy
ORCID: https://orcid.org/0000-0003-4509-7056, Diecke, Sebastian
ORCID: https://orcid.org/0000-0002-5219-5992, Ivanov, Andranik
ORCID: https://orcid.org/0000-0002-4824-1925, Kovács, Richard, Beule, Dieter
ORCID: https://orcid.org/0000-0002-3284-0632, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Brüning, Ulrike
ORCID: https://orcid.org/0000-0003-0112-4032, Kirwan, Jennifer A.
ORCID: https://orcid.org/0000-0002-5423-1651, Stachelscheid, Harald
ORCID: https://orcid.org/0000-0002-9283-4605, Endres, Matthias
ORCID: https://orcid.org/0000-0001-6520-3720, Huehnchen, Petra
ORCID: https://orcid.org/0000-0002-6825-7270 and Boehmerle, Wolfgang
ORCID: https://orcid.org/0000-0001-7195-3894
Cell Death & Disease 17
(1): 211.
19 February 2026
Human ADA2 deficiency is characterized by the absence of an intracellular hypoglycosylated form of adenosine deaminase 2.
Ehlers, L.
ORCID: https://orcid.org/0000-0001-8737-001X, Wouters, M.
ORCID: https://orcid.org/0000-0002-4675-1665, Hombrouck, A.
ORCID: https://orcid.org/0009-0003-5236-6063, Pillay, B.
ORCID: https://orcid.org/0000-0001-7964-544X, Delafontaine, S.
ORCID: https://orcid.org/0000-0002-8985-8155, Bucciol, G.
ORCID: https://orcid.org/0000-0001-5004-0738, Baggio, M.
ORCID: https://orcid.org/0000-0001-6708-9925, Dzhus, M.
ORCID: https://orcid.org/0000-0002-2077-4295, Francés Rabanal, E., Damerau, A.
ORCID: https://orcid.org/0000-0001-6651-2963, Neugebauer, J.
ORCID: https://orcid.org/0000-0002-2576-1012, Ebstein, F.
ORCID: https://orcid.org/0000-0002-3729-7878, Jacquemyn, M.
ORCID: https://orcid.org/0000-0003-2626-4189, De Somer, L.
ORCID: https://orcid.org/0000-0002-8488-5090, Schrijvers, R.
ORCID: https://orcid.org/0000-0002-4261-6220, Vanderschueren, S.
ORCID: https://orcid.org/0000-0002-4003-5465, Cassiman, D.
ORCID: https://orcid.org/0000-0002-6154-0970, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Mashreghi, M.F., Kallinich, T.
ORCID: https://orcid.org/0000-0003-2404-9397, Daelemans, D.
ORCID: https://orcid.org/0000-0001-7092-1153, Agostinis, P.
ORCID: https://orcid.org/0000-0003-1314-2115, Moens, L.
ORCID: https://orcid.org/0000-0002-5347-6526 and Meyts, I.
ORCID: https://orcid.org/0000-0003-1214-0302
bioRxiv
: 2023.10.25.564037.
16 February 2026
Seeing elephants and drinking water from a porcelain vase - a case of septin-7 antibody-associated encephalitis presenting as a severe disorganized psychosis.
Gaebler, Arnim Johannes
ORCID: https://orcid.org/0000-0002-8816-3415, Arlt, Friederike A
ORCID: https://orcid.org/0000-0002-0112-8685, Scharf, Madeleine, Wolking, Stefan, Weber, Yvonne
ORCID: https://orcid.org/0000-0002-0806-5592, Tauber, Simone, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Boy, Christian, Neuner, Irene
ORCID: https://orcid.org/0000-0002-5164-8873, Frodl, Thomas
ORCID: https://orcid.org/0000-0002-8113-6959, Tebartz van Elst, Ludger
ORCID: https://orcid.org/0000-0002-2274-5447, Prüss, Harald
ORCID: https://orcid.org/0000-0002-8283-7976 and Novakovic, Ana
Translational Psychiatry 16
(1): 71.
11 February 2026
Multi-omics insight into cardiac myofibril remodeling in post-prandial burmese pythons.
Martin, Thomas G.
ORCID: https://orcid.org/0000-0002-1300-4890, Suarez-Artiles, Lorena
ORCID: https://orcid.org/0000-0001-7991-5446, Woulfe, Kathleen C., Melhedegaard, Elise G., Tan, Yuxiao, Hunt, Dakota R., Kirkpatrick, Bruce E., Nguyen, Lia, Lee, Joseph, Laskey, Isabella, Anseth, Kristi S., Ochala, Julien, Gotthardt, Michael
ORCID: https://orcid.org/0000-0003-1788-3172, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X and Leinwand, Leslie A.
ORCID: https://orcid.org/0000-0003-1470-4810
bioRxiv
: 2026.02.02.703272.
4 February 2026
Changes in sputum viscoelastic properties and airway inflammation in primary ciliary dyskinesia are comparable to cystic fibrosis on elexacaftor/tezacaftor/ivacaftor therapy.
Nussstein, Hannah, Urbantat, Ruth M., Fentker, Kerstin
ORCID: https://orcid.org/0009-0005-0437-1049, Loewe, Aditi, Duerr, Julia
ORCID: https://orcid.org/0000-0002-4862-9487, Haji, Mohamed, Doellinger, Felix, Stahl, Mirjam
ORCID: https://orcid.org/0000-0001-6941-8315, Graeber, Simon Y.
ORCID: https://orcid.org/0000-0002-1666-8924, Gradzielski, Michael, Röhmel, Jobst
ORCID: https://orcid.org/0000-0002-1535-8852, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Schaupp, Laura and Mall, Marcus A.
ORCID: https://orcid.org/0000-0002-4057-2199
European Respiratory Journal 67
(2): 2500616.
February 2026
Targeting mutual dependence of phosphatidylinositol-3-kinase α/δ and small ubiquitin-like modifier signaling in pancreatic cancer.
Köse, Hazal, Schneeweis, Christian, Putze, Philipp, Contreras, Constanza Tapia, Ferreiro, Laura, Witte, Leonie, Deidda, Ilaria, Herzberg, Frederik, Ebert, Sophie, Jakubik, Juraj, Moldaner, Leoni, Todorovic, Jovan, Träger, Isabelle, Zang, Chuanbing, Demel, Uta M.
ORCID: https://orcid.org/0000-0002-6480-4185, Hessmann, Elisabeth, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Rhein, Simone
ORCID: https://orcid.org/0000-0002-9445-2352, Hoffmann, Jens
ORCID: https://orcid.org/0000-0003-3880-1658, Tatarova, Zuzana, Ghadimi, Michael, Saur, Dieter, Kappert, Kai, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Schneider, Günter, Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958 and Wirth, Matthias
ORCID: https://orcid.org/0000-0002-8340-0872
Gastroenterology 170
(2): 315-329.
February 2026
TENM4 is an essential transduction component for touch.
Khallaf, Mohammed A.
ORCID: https://orcid.org/0000-0002-1402-3858, Huang, Angela Tzu-Lun
ORCID: https://orcid.org/0000-0003-3471-192X, Dalmasso, Letizia, Chakrabarti, Sampurna
ORCID: https://orcid.org/0000-0002-2750-3877, Groeneveld, Rowena
ORCID: https://orcid.org/0009-0009-1898-9957, Sierra, Yinth Andrea Bernal, Garcia-Contreras, Jonathan Alexis, Nello, Emilie
ORCID: https://orcid.org/0009-0001-3622-9849, Schütz, Anja
ORCID: https://orcid.org/0000-0002-0606-2574, Bégay, Valérie
ORCID: https://orcid.org/0000-0002-9002-4211, Santuz, Alessandro
ORCID: https://orcid.org/0000-0002-6577-5101, Hedtrich, Sarah
ORCID: https://orcid.org/0000-0001-6770-3657, Zhong, Wei, Schiel, Christina, Middleton, Steven J.
ORCID: https://orcid.org/0000-0002-0708-7335, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Zampieri, Niccolò
ORCID: https://orcid.org/0000-0002-2228-9453, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Kunz, Severine
ORCID: https://orcid.org/0000-0002-0131-3506 and Lewin, Gary R.
ORCID: https://orcid.org/0000-0002-2890-6352
bioRxiv
: 2024.10.10.617546v2.
18 January 2026
Changes in sputum viscoelastic properties and airway inflammation in primary ciliary dyskinesia are comparable to cystic fibrosis on elexacaftor/tezacaftor/ivacaftor therapy.
Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X and Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X
[Dataset]
12 January 2026
Systematic evaluation of neoepitope predictions challenges clinically observed T-cell responses and their impact on immune evasion.
Zaghla, Badeel Kh Q.
ORCID: https://orcid.org/0009-0002-2675-8859, Safürek, Zuhal
ORCID: https://orcid.org/0009-0004-8412-5069, Gröger, Daniela, Mecklenbräuker, Shima, Lingstädt, Nina-Sophie, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Spengler, Johanna, Haji, Mohamed, Montesion, Meagan, Albacker, Lee A., Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X and Klatt, Martin G.
ORCID: https://orcid.org/0000-0001-8703-7305
Journal for ImmunoTherapy of Cancer 14
(1): e013271.
January 2026
2025
Multi-omics analysis reveals vitamin D metabolism, hyper-IgE genes, and epithelial barrier dysfunction in hazelnut allergy.
Jeanrenaud, Alexander C.S.N.
ORCID: https://orcid.org/0000-0002-4230-9976, Arnau-Soler, Aleix
ORCID: https://orcid.org/0000-0001-9768-0513, Ghauri, Ahla
ORCID: https://orcid.org/0000-0003-4665-3624, Marenholz, Ingo
ORCID: https://orcid.org/0009-0007-6933-3849, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Beyer, Kirsten
ORCID: https://orcid.org/0000-0003-1859-0419, Worm, Margitta
ORCID: https://orcid.org/0000-0002-3449-1245 and Lee, Young-Ae
ORCID: https://orcid.org/0000-0002-1817-9163
bioRxiv
: 2025.12.11.692994.
13 December 2025
Plasma proteomics in acute heart failure: survival-associated protein signatures and 90-day trajectories.
Chitroceanu, Alexandra M., Fahjen, Pauline
ORCID: https://orcid.org/0000-0002-5015-0643, Schulze, Daniel, Zach, Veronika, Alasfar, Lina, Ziehm, Matthias
ORCID: https://orcid.org/0000-0001-7074-4054, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Niquet, Sylvia, Dahmen, Jan-Niklas, Plappert, Carlos, Kretzler, Lucie, Kind, Andreas, Zurkan, Daniela, Pinto, Rafaela Maria, Reynolds, Edwardo, Trippel, Tobias D., Forslund, Sofia
ORCID: https://orcid.org/0000-0003-4285-6993, Grittner, Ulrike, Mai, Knut, Gotthardt, Michael
ORCID: https://orcid.org/0000-0003-1788-3172, Schiattarella, Gabriele G.
ORCID: https://orcid.org/0000-0002-7582-7171, Kintscher, Ulrich, Ahmadi, Michael, Boldt, Leif-Hendrik, Buchmann, Nikolaus, Eckardt, Kai-Uwe, Endres, Matthias, Gerhardt, Holger
ORCID: https://orcid.org/0000-0002-3030-0384, Hübner, Norbert
ORCID: https://orcid.org/0000-0002-1218-6223, Kollmus-Heege, Jil, Landmesser, Ulf, Müller, Dominik N.
ORCID: https://orcid.org/0000-0003-3650-5644, Nolte, Christian H., Piper, Sophie K., Rattan, Simrit, Rohrpasser-Napierkowski, Ira, Schönrath, Katharina, Schulz-Menger, Jeanette
ORCID: https://orcid.org/0000-0003-3100-1092, Schweizerhof, Oliver, Pischon, Tobias
ORCID: https://orcid.org/0000-0003-1568-767X, Pieske, Burkert
ORCID: https://orcid.org/0000-0002-6466-5306, Weber, Joachim, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X and Edelmann, Frank
medRxiv
: 2025.12.01.25341310.
3 December 2025
Computational modelling of myocardial metabolism in patients with advanced heart failure.
Beyhoff, Niklas, Braun, Vera M., Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Finnigan, Lucy E. M., Knosalla, Christoph, Baczkó, István, Potapov, Evgenij, Kintscher, Ulrich, Grune, Tilman, Kuehne, Titus, Holzhütter, Hermann-Georg, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Tyler, Damian J., Milting, Hendrik, Raman, Betty, Rider, Oliver J., Neubauer, Stefan and Berndt, Nikolaus
European Journal of Heart Failure 27
(12): 3411-3422.
December 2025
Deep phenotyping of heart failure with preserved ejection fraction through multi-omics integration.
Versnjak, Jakob
ORCID: https://orcid.org/0009-0009-6179-1014, Kuehne, Titus
ORCID: https://orcid.org/0000-0003-1631-4824, Fahjen, Pauline
ORCID: https://orcid.org/0000-0002-5015-0643, Jovanovic, Nina
ORCID: https://orcid.org/0000-0001-6300-9705, Löber, Ulrike
ORCID: https://orcid.org/0000-0001-7468-9531, Schiattarella, Gabriele G.
ORCID: https://orcid.org/0000-0002-7582-7171, Wilck, Nicola
ORCID: https://orcid.org/0000-0003-3189-5364, Gerhardt, Holger
ORCID: https://orcid.org/0000-0002-3030-0384, Müller, Dominik N.
ORCID: https://orcid.org/0000-0003-3650-5644, Edelmann, Frank
ORCID: https://orcid.org/0000-0003-4401-5936, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Eils, Roland
ORCID: https://orcid.org/0000-0002-0034-4036, Gotthardt, Michael
ORCID: https://orcid.org/0000-0003-1788-3172, Forslund, Sofia K.
ORCID: https://orcid.org/0000-0003-4285-6993, Wild, Benjamin
ORCID: https://orcid.org/0000-0002-7492-8448 and Kelm, Marcus
ORCID: https://orcid.org/0000-0003-4971-0452
European Journal of Heart Failure 27
(12): 3243-3259.
December 2025
Remodelling of the endothelial extracellular matrix promotes smooth muscle cell hyperplasia in pulmonary hypertension due to left heart disease.
Nambiar Veetil, Netra, Gransar, Tara, Liu, Shao-Fei, Almalla, Ahed, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Brackin-Helmers, Robyn, Hennig, Felix, Yeter, Ruhi, Weinhart, Marie, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Falk, Volkmar
ORCID: https://orcid.org/0000-0002-7911-8620, Szulcek, Robert
ORCID: https://orcid.org/0000-0003-0450-7338, Kucherenko, Mariya M.
ORCID: https://orcid.org/0000-0002-8637-2037, Kuebler, Wolfgang M.
ORCID: https://orcid.org/0000-0003-4100-2961 and Knosalla, Christoph
ORCID: https://orcid.org/0000-0002-8127-5019
Cardiovascular Research 121
(18): 2939-2953.
December 2025
Butyrate rescues cardiac metabolic dysfunction in hypertensive heart failure with preserved ejection fraction.
Kedziora, Sarah M.
ORCID: https://orcid.org/0000-0003-0124-2557, Geisberger, Sabrina Y.
ORCID: https://orcid.org/0000-0001-6477-1312, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Frolova, Alina
ORCID: https://orcid.org/0000-0001-5469-7366, Uhrbach, Alisa, Kräker, Kristin
ORCID: https://orcid.org/0000-0002-4032-5382, Tagiyeva, Nurana
ORCID: https://orcid.org/0009-0006-7918-1220, Kelm, Marcus, Berndt, Nikolaus, Zhang, Yiming D.
ORCID: https://orcid.org/0009-0003-9465-2033, Mastrobuoni, Guido
ORCID: https://orcid.org/0000-0003-4509-1295, Escrihuela-Branz, Raquel, Bartolomaeus, Theda U.P.
ORCID: https://orcid.org/0000-0002-5156-7184, Pixner, Lorenz, Fahjen, Pauline
ORCID: https://orcid.org/0000-0002-5015-0643, Kaufhold, Gelsomina N.
ORCID: https://orcid.org/0009-0009-0868-3284, Parakkat, Pragati
ORCID: https://orcid.org/0000-0003-2691-791X, Chitroceanu, Alexandra Maria, Tschöpe, Carsten, Edelmann, Frank, Schiattarella, Gabriele G.
ORCID: https://orcid.org/0000-0002-7582-7171, Forslund, Sofia K.
ORCID: https://orcid.org/0000-0003-4285-6993, Wilck, Nicola
ORCID: https://orcid.org/0000-0003-3189-5364, Gotthardt, Michael
ORCID: https://orcid.org/0000-0003-1788-3172, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Dechend, Ralf
ORCID: https://orcid.org/0000-0001-6636-3080, Sawamiphak, Suphansa
ORCID: https://orcid.org/0000-0003-2298-3565, Müller, Dominik N.
ORCID: https://orcid.org/0000-0003-3650-5644, Kempa, Stefan
ORCID: https://orcid.org/0000-0002-0696-9299 and Haase, Nadine
ORCID: https://orcid.org/0000-0003-0727-1738
bioRxiv
: 2025.11.28.690152.
30 November 2025
Myeloid cell recruitment propels right ventricular dysfunction in HFpEF via sterile inflammation.
Jaeschke, Lara
ORCID: https://orcid.org/0009-0004-1847-5378, Kocana, Ceren, Chitroceanu, Alexandra Maria, Winkler, Annika, Kleitke, Hannah, Fahjen, Pauline
ORCID: https://orcid.org/0000-0002-5015-0643, Faidel, David
ORCID: https://orcid.org/0000-0001-9606-9595, Asmus, Erik
ORCID: https://orcid.org/0000-0003-4740-7724, Meiser, Martin, Stamatiades, Efstathios G., Hublitz, Karolin W, Zach, Veronika, Kretzler, Lucie, Zurkan, Daniela, Perret, Paul-Lennard, von der Ohe, Leonardo Axel, Simmons, Szandor
ORCID: https://orcid.org/0000-0002-5309-9863, Gillan, Jonathan L.
ORCID: https://orcid.org/0000-0002-9017-253X, Franz, Kristina
ORCID: https://orcid.org/0000-0002-3819-9671, Alasfar, Lina, Hahn, Virginia Shalkey
ORCID: https://orcid.org/0000-0002-0578-2668, Sharma, Kavita
ORCID: https://orcid.org/0000-0002-3012-1765, Reynolds, Edwardo, Schiattarella, Gabriele G.
ORCID: https://orcid.org/0000-0002-7582-7171, Van Linthout, Sophie
ORCID: https://orcid.org/0000-0002-7581-7870, Pieske, Burkert
ORCID: https://orcid.org/0000-0002-6466-5306, Hegemann, Niklas
ORCID: https://orcid.org/0000-0002-2898-0798, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Edelmann, Frank, Kuebler, Wolfgang M.
ORCID: https://orcid.org/0000-0003-4100-2961 and Grune, Jana
ORCID: https://orcid.org/0000-0001-6209-7416
bioRxiv
: 2025.11.21.689863.
23 November 2025
BIRC5 dependency defines a targetable vulnerability in TP53 mutant acute myeloid leukemia.
Mamdouh, Ahmed M., Lim, Fang Qi, Mi, Yang, Olesinski, Elyse A., Jasdanwala, Shaista, Lin, Xiao Xian, Ayoub, Edward, Tan, Jordan Yong Ming, Bhatia, Karanpreet Singh, Wang, Yichen, Garnaik, Shradha, Tomar, Kunal, Sapozhnikova, Valeriia, Chan, Cheryl Gek Teng, Wang, Chuqi, Mahesh, Aarthi Nivasini, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Brown, Brandon D., Haferlach, Torsten, Ooi, Melissa, Lobry, Camille, Puissant, Alexandre, Taylor, Justin, Abbas, Hussein, Kornblau, Steven M., Miller, Peter G., Das, Sanjukta, Krönke, Jan, Itahana, Koji, Andreeff, Michael and Bhatt, Shruti
bioRxiv
: 2025.05.17.654633v2.
15 November 2025
Phosphoprofile reorganization of the actin binding protein Drebrin during long term depression.
Silva, Rafaela Pedro, Mack, Till G.A., Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Eickholt, Britta J. and Kreis, Patricia
Frontiers in Molecular Neuroscience 18
: 1697642.
5 November 2025
AI-powered spatial cell phenomics enhances risk stratification in non-small cell lung cancer.
Schallenberg, Simon, Dernbach, Gabriel, Ruane, Sharon, Jurmeister, Philipp
ORCID: https://orcid.org/0000-0001-7745-3794, Böhm, Cornelius
ORCID: https://orcid.org/0009-0007-3754-4182, Standvoss, Kai, Ghosh, Sandip
ORCID: https://orcid.org/0009-0008-7342-1064, Frentsch, Marco, Dragomir, Mihnea P
ORCID: https://orcid.org/0000-0002-5550-3516, Keyl, Philipp G
ORCID: https://orcid.org/0000-0002-5472-4683, Friedrich, Corinna
ORCID: https://orcid.org/0000-0002-5586-1989, Na, Il-Kang
ORCID: https://orcid.org/0000-0001-9902-5424, Merkelbach-Bruse, Sabine, Quaas, Alexander, Frost, Nikolaj
ORCID: https://orcid.org/0000-0001-7452-7129, Boschung, Kyrill, Randerath, Winfried, Schlachtenberger, Georg, Heldwein, Matthias
ORCID: https://orcid.org/0000-0002-2084-795X, Keilholz, Ulrich, Hekmat, Khosro, Rückert, Jens-Carsten, Büttner, Reinhard
ORCID: https://orcid.org/0000-0001-8806-4786, Vasaturo, Angela, Horst, David, Ruff, Lukas, Alber, Maximilian, Müller, Klaus-Robert
ORCID: https://orcid.org/0000-0002-3861-7685 and Klauschen, Frederick
ORCID: https://orcid.org/0000-0002-9131-2389
Nature Communications 16
(1): 9701.
3 November 2025
Early detection of acute kidney injury after congenital heart surgery - using urine proteomics to identify new biomarker candidates: a prospective clinical study.
Seiler, Raphael
ORCID: https://orcid.org/0000-0002-8842-7572, Herre, Alexa Leona, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Ziehm, Matthias
ORCID: https://orcid.org/0000-0001-7074-4054, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Berger, Felix
ORCID: https://orcid.org/0000-0001-7881-1557, Photiadis, Joachim, Tong, Giang, Brankova, Liliya, Schmitt, Katharina R.L. and Lücht, Jana
ORCID: https://orcid.org/0000-0001-8687-8313
Journal of Clinical Medicine 14
(22): 8253.
November 2025
Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling.
Piletic, Klara, Kayvanjoo, Amir H.
ORCID: https://orcid.org/0000-0003-1315-8336, Richter, Felix Clemens
ORCID: https://orcid.org/0000-0002-3415-3449, Borsa, Mariana
ORCID: https://orcid.org/0000-0003-1519-2597, Lechuga-Vieco, Ana V.
ORCID: https://orcid.org/0000-0001-5546-9752, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Grenet, Sacha
ORCID: https://orcid.org/0009-0000-4028-8895, Ko, Jacky Ka Long, Luo, Lin
ORCID: https://orcid.org/0000-0003-2300-5448, Zec, Kristina, Kyriazi, Maria, Haysom, Harriet K.
ORCID: https://orcid.org/0000-0001-8950-8289, Koneva, Lada
ORCID: https://orcid.org/0000-0002-9529-4886, Sansom, Stephen
ORCID: https://orcid.org/0000-0003-4569-8513, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Powrie, Fiona
ORCID: https://orcid.org/0000-0003-3312-5929, Alsaleh, Ghada and Simon, Anna Katharina
ORCID: https://orcid.org/0000-0002-4077-7995
Nature Communications 16
(1): 9220.
17 October 2025
Phosphoprofile reorganization of the actin binding protein Drebrin during long term depression.
Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X and Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X
[Dataset]
17 October 2025
Deep coverage multi-omic profiling of C2C12 dexamethasone skeletal muscle atrophy.
Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666 and Nakagawa, Suzuka
ORCID: https://orcid.org/0000-0002-9417-9499
[Dataset]
14 October 2025
Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set.
Distler, Ute
ORCID: https://orcid.org/0000-0002-8031-6384, Yoo, Han Byul, Kardell, Oliver, Hein, Dana, Sielaff, Malte, Scherer, Marian, Jozefowicz, Anna M., Leps, Christian, Gomez-Zepeda, David
ORCID: https://orcid.org/0000-0002-9467-1213, von Toerne, Christine
ORCID: https://orcid.org/0000-0002-4132-4322, Merl-Pham, Juliane
ORCID: https://orcid.org/0000-0002-3422-4083, Barth, Teresa K., Tüshaus, Johanna
ORCID: https://orcid.org/0000-0001-9206-8093, Giesbertz, Pieter
ORCID: https://orcid.org/0000-0001-7461-8602, Müller, Torsten, Kliewer, Georg, Aljakouch, Karim, Helm, Barbara, Unger, Henry
ORCID: https://orcid.org/0009-0001-1798-4347, Frey, Dario L.
ORCID: https://orcid.org/0000-0001-9572-9686, Helm, Dominic
ORCID: https://orcid.org/0000-0001-9321-2069, Schwarzmüller, Luisa
ORCID: https://orcid.org/0000-0002-7151-9913, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Qin, Di
ORCID: https://orcid.org/0000-0002-9730-4072, Wudy, Susanne I.
ORCID: https://orcid.org/0009-0001-6333-5233, Sinn, Ludwig Roman
ORCID: https://orcid.org/0000-0003-4692-0681, Mergner, Julia
ORCID: https://orcid.org/0000-0002-4332-1280, Ludwig, Christina
ORCID: https://orcid.org/0000-0002-6131-7322, Imhof, Axel
ORCID: https://orcid.org/0000-0003-2993-8249, Kuster, Bernhard
ORCID: https://orcid.org/0000-0002-9094-1677, Lichtenthaler, Stefan F.
ORCID: https://orcid.org/0000-0003-2211-2575, Krijgsveld, Jeroen, Klingmüller, Ursula, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Coscia, Fabian
ORCID: https://orcid.org/0000-0002-2244-5081, Ralser, Markus
ORCID: https://orcid.org/0000-0001-9535-7413, Mülleder, Michael
ORCID: https://orcid.org/0000-0001-9792-3861, Hauck, Stefanie M.
ORCID: https://orcid.org/0000-0002-1630-6827 and Tenzer, Stefan
ORCID: https://orcid.org/0000-0003-3034-0017
Nature Communications 16
(1): 8774.
2 October 2025
Early regulation and alternative splicing dynamics in glucocorticoid muscle atrophy revealed by temporal omics in C2C12 myotubes.
Nakagawa, Suzuka
ORCID: https://orcid.org/0000-0002-9417-9499, Misios, Aristotelis, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Jarosch, Ernst
ORCID: https://orcid.org/0000-0002-5897-3492, Fielitz, Jens
ORCID: https://orcid.org/0000-0001-8522-1045 and Sommer, Thomas
ORCID: https://orcid.org/0000-0001-9990-5202
American Journal of Physiology Cell Physiology 329
(4): C1300-C1315.
October 2025
Adipocyte autophagy-mediated signals in the control of macrophage phenotype during diet-induced obesity.
Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666 and Simon, Katja
ORCID: https://orcid.org/0000-0002-4077-7995
[Dataset]
26 September 2025
Phosphorylation of presynaptic PLPPR3 controls synaptic vesicle release.
Kroon, Cristina, Bareesel, Shannon, Aguilar Perez, Gerard, Nagy-Herczeg, Domonkos, Ranti, Dimitra, Syropoulou, Vasiliki, Coveney, Sandra, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Gimber, Niclas
ORCID: https://orcid.org/0000-0001-9456-3063, Bintig, Willem, Brosig, Annika, Braune, Georg, Textoris-Taube, Kathrin, Zolnik, Timothy A., Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Schmoranzer, Jan, Milovanovic, Dragomir, Leondaritis, George and Eickholt, Britta J.
ORCID: https://orcid.org/0000-0001-7873-8687
iScience 28
(9): 113435.
19 September 2025
Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome.
Boehm, Volker, Wallmeroth, Damaris, Wulf, Paul O.
ORCID: https://orcid.org/0009-0002-6356-2361, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Teixeira Alves, Luiz Gustavo
ORCID: https://orcid.org/0000-0002-5822-4168, Reinecke, Lucie
ORCID: https://orcid.org/0009-0003-7083-0923, Riedel, Maximilian
ORCID: https://orcid.org/0009-0002-9817-3083, Wyler, Emanuel
ORCID: https://orcid.org/0000-0002-9884-1806, Franitza, Marek, Becker, Kerstin, Polkovnychenko, Karina, Del Giudice, Simone
ORCID: https://orcid.org/0000-0003-0194-3767, Benlasfer, Nouhad, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Landthaler, Markus
ORCID: https://orcid.org/0000-0002-1075-8734 and Gehring, Niels H.
Molecular Cell 85
(18): 3524-3546.e12.
18 September 2025
Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome.
Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666 and Boehm, Volker
[Dataset]
3 September 2025
An acetylated Lysine Residue of Its Low-glucose Inhibitory Domain Controls Activity and Protein Interactions of ChREBP.
Petricek, K.M., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Sommerfeld, M., Stephanowitz, H., Kiefer, M.F.
ORCID: https://orcid.org/0000-0002-6344-2856, Meng, Y., Dittrich, S., Dähnhardt, H.E., Mai, K., Krause, E., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Wowro, S.J. and Schupp, M.
Journal of Molecular Biology 437
(17): 169189.
1 September 2025
Dataset: rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome.
Boehm, Volker
ORCID: https://orcid.org/0000-0001-7588-9842, Wallmeroth, Damaris
ORCID: https://orcid.org/0000-0003-3437-4070, Wulf, Paul O.
ORCID: https://orcid.org/0009-0002-6356-2361, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Teixeira Alves, Luiz Gustavo
ORCID: https://orcid.org/0000-0002-5822-4168, Reinecke, Lucie
ORCID: https://orcid.org/0009-0003-7083-0923, Riedel, Maximilian
ORCID: https://orcid.org/0009-0002-9817-3083, Wyler, Emanuel
ORCID: https://orcid.org/0000-0002-9884-1806, Franitza, Marek, Becker, Kerstin
ORCID: https://orcid.org/0009-0009-7897-7181, Polkovnychenko, Karina
ORCID: https://orcid.org/0009-0001-9468-3150, Del Giudice, Simone
ORCID: https://orcid.org/0000-0003-0194-3767, Benlasfer, Nouhad, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Landthaler, Markus
ORCID: https://orcid.org/0000-0002-1075-8734 and Gehring, Niels H.
[Dataset]
31 August 2025
Carbon-based nanostructure drug delivery systems and their biologic applications – a review.
Alvandi, H., Shafie, A., Najafi, F., Sabzini, M., Mashayekhi, M., Omami, S.H., Eskandarisani, M.M., Dashti, S.
ORCID: https://orcid.org/0009-0005-7286-1744, Javanmard, A., Tajik, M., Bräse, S. and Farmani, A.R.
ORCID: https://orcid.org/0000-0003-1149-3843
Carbon Letters 35
(4): 1529-1587.
August 2025
Hepatitis B virus-infected hepatocytes promote the secretion of collagen VI to the extracellular matrix.
Virzì, A., Boulahtouf, Z., Moehlin, J., Girard, L., Meiss-Heydmann, L., Bach, C., Gerges, E., Durand, S.C., Oudot, M.A., Roca Suarez, A.A., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Ramberger, E.
ORCID: https://orcid.org/0000-0003-2760-2696, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Felli, E., Pessaux, P., Schuster, C., Verrier, E.R., Baumert, T.F. and Lupberger, J.
Scientific Reports 15
(1): 24949.
10 July 2025
Novel non-coding FOXP3 transcript isoform associated to potential transcriptional interference in human regulatory T cells.
Cases, M., Ritter, N., Rincon-Arevalo, H., Kroh, S., Adam, A., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Moradian, H., Gossen, M.
ORCID: https://orcid.org/0000-0002-1761-4063, Dzamukova, M., Manukyan, A.
ORCID: https://orcid.org/0000-0002-0441-9517, Landthaler, M.
ORCID: https://orcid.org/0000-0002-1075-8734, Kressler, C., Hauser, A.E., Depledge, D.P., Polansky, J.K. and Chang, H.D.
RNA Biology 22
(1): 1-20.
2 July 2025
Spike-in enhanced phosphoproteomics uncovers synergistic signaling responses to MEK inhibition in colon cancer cells.
van Bentum, M., Klinger, B.
ORCID: https://orcid.org/0000-0003-0242-1506, Sieber, A.
ORCID: https://orcid.org/0000-0001-6588-8547, Naghiloo, S.
ORCID: https://orcid.org/0009-0001-7354-2930, Zauber, H.
ORCID: https://orcid.org/0000-0003-2595-1147, Lehmann, N.
ORCID: https://orcid.org/0009-0006-2588-2283, Haji, M., Niquet, S., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Blüthgen, N.
ORCID: https://orcid.org/0000-0002-0171-7447 and Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751
Nature Communications 16
(1): 4884.
27 May 2025
Structural determinants of mucins in influenza virus inhibition: the role of sialylated glycans and molecular size.
Butnarasu, C., Safferthal, M., Thomas, J., Povolotsky, T.L., Diehn, R., Fentker, K.
ORCID: https://orcid.org/0009-0005-0437-1049, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Pagel, K. and Lauster, D.C.
International Journal of Biological Macromolecules 307
(Part 4): 142357.
May 2025
UBE3C links ubiquitin signaling to epitranscriptomic control of cortical neurogenesis.
Borisova, Ekaterina, Cuthill, Katherine J.
ORCID: https://orcid.org/0000-0003-3328-3249, Dannenberg, Rike, Koch, Janina, Nowaczyk, Julius
ORCID: https://orcid.org/0009-0009-7068-4958, Schaub, Theres, Schwark, Manuela
ORCID: https://orcid.org/0009-0008-1711-457X, Kastelic, N., Kupryianchyk-Schultz, I.
ORCID: https://orcid.org/0009-0007-6442-4469, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Pentimalli, T.M.
ORCID: https://orcid.org/0000-0002-8461-7918, Fokkens, T.J.
ORCID: https://orcid.org/0009-0005-4689-4024, Stein, F., Dietrich, C., Quedenau, C.
ORCID: https://orcid.org/0000-0002-6846-4915, Borodina, T.
ORCID: https://orcid.org/0000-0002-6978-016X, Schwefel, D.
ORCID: https://orcid.org/0000-0002-2945-0908, Conrad, T.
ORCID: https://orcid.org/0000-0001-5618-6295, Rybak-Wolf, A.
ORCID: https://orcid.org/0000-0002-1192-5290, Rajewsky, N.
ORCID: https://orcid.org/0000-0002-4785-4332, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Haberkant, P.
ORCID: https://orcid.org/0000-0002-5608-9062, Lorenz, S.
ORCID: https://orcid.org/0000-0002-9639-2381, Brose, N.
ORCID: https://orcid.org/0000-0003-0938-8534, Kawabe, H.
ORCID: https://orcid.org/0000-0001-5650-8696, Tarabykin, V.
ORCID: https://orcid.org/0000-0001-8931-7263 and Ambrozkiewicz, M.C.
ORCID: https://orcid.org/0000-0001-5225-5230
bioRxiv
: 2025.04.09.646620v2.
29 April 2025
Intestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface.
Avery, E.G.
ORCID: https://orcid.org/0000-0002-9094-1423, Haag, L.M., McParland, V.
ORCID: https://orcid.org/0000-0003-0731-3272, Kedziora, S.M.
ORCID: https://orcid.org/0000-0003-0124-2557, Zigra, G.J., Valdes, D.S.
ORCID: https://orcid.org/0000-0002-1309-5147, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Geisberger, S.
ORCID: https://orcid.org/0000-0001-6477-1312, Nonn, O.
ORCID: https://orcid.org/0000-0001-6385-2866, Karlsen, T.V., N'Diaye, G., Yarritu, A.
ORCID: https://orcid.org/0000-0002-1724-0559, Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828, Bartolomaeus, T.U.P.
ORCID: https://orcid.org/0000-0002-5156-7184, Tagiyeva, N.A.
ORCID: https://orcid.org/0009-0006-7918-1220, Wimmer, M.I.
ORCID: https://orcid.org/0009-0004-5793-0249, Haase, N.
ORCID: https://orcid.org/0000-0003-0727-1738, Zhang, Y.D.
ORCID: https://orcid.org/0009-0003-9465-2033, Wilhelm, A., Grütz, G., Tenstad, O., Wilck, N.
ORCID: https://orcid.org/0000-0003-3189-5364, Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993, Klopfleisch, R., Kühl, A.A., Atreya, R., Kempa, S.
ORCID: https://orcid.org/0000-0002-0696-9299, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Siegmund, B., Wiig, H.
ORCID: https://orcid.org/0000-0002-7740-8210 and Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644
Cardiovascular Research 121
(5): 803-816.
April 2025
LINC01503-MP is a mitochondrial microprotein that promotes cell proliferation and oxidative metabolism.
Dewani, N.
ORCID: https://orcid.org/0000-0002-2287-6674, Ruiz-Orera, J.
ORCID: https://orcid.org/0000-0002-8317-0034, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Liang, N.
ORCID: https://orcid.org/0009-0008-8137-6873, Sugarawa, M.
ORCID: https://orcid.org/0000-0001-7146-533X, Schulz, J.F.
ORCID: https://orcid.org/0000-0002-8157-2224, Witte, F., Sandmann, C.
ORCID: https://orcid.org/0000-0002-3847-0708, Tsuji, T.
ORCID: https://orcid.org/0000-0001-9810-7305, Blachut, S.
ORCID: https://orcid.org/0009-0007-0102-9867, Katagiri, T., Kondova, I., Owada, S., Yoshii, S., Kataoka, H.
ORCID: https://orcid.org/0000-0002-2502-8304, Kurtz, A.
ORCID: https://orcid.org/0000-0003-3301-6546, Nakase, H.
ORCID: https://orcid.org/0000-0003-2848-6586, van Heesch, S.
ORCID: https://orcid.org/0000-0001-9593-1980, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223 and Kanda (Hübner), M.
ORCID: https://orcid.org/0000-0003-3468-3586
bioRxiv
: 2025.03.19.644091.
19 March 2025
Multicenter longitudinal quality assessment of MS-based proteomics in plasma and serum.
Kardell, O.
ORCID: https://orcid.org/0000-0002-6703-7997, Gronauer, T., von Toerne, C., Merl-Pham, J., König, A.C., Barth, T.K., Mergner, J., Ludwig, C.
ORCID: https://orcid.org/0000-0002-6131-7322, Tüshaus, J., Giesbertz, P., Breimann, S.
ORCID: https://orcid.org/0000-0002-0305-3373, Schweizer, L., Müller, T., Kliewer, G., Distler, U.
ORCID: https://orcid.org/0000-0002-8031-6384, Gomez-Zepeda, D.
ORCID: https://orcid.org/0000-0002-9467-1213, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Qin, D.
ORCID: https://orcid.org/0000-0002-9730-4072, Teupser, D., Cox, J.
ORCID: https://orcid.org/0000-0001-8597-205X, Imhof, A.
ORCID: https://orcid.org/0000-0003-2993-8249, Küster, B.
ORCID: https://orcid.org/0000-0002-9094-1677, Lichtenthaler, S.F., Krijgsveld, J., Tenzer, S.
ORCID: https://orcid.org/0000-0003-3034-0017, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Coscia, F.
ORCID: https://orcid.org/0000-0002-2244-5081 and Hauck, S.M.
ORCID: https://orcid.org/0000-0002-1630-6827
Journal of Proteome Research 24
(3): 1017-1029.
7 March 2025
Formation of amyloid-like HTTex1 aggregates in neurons, downregulation of synaptic proteins and early mortality of Huntington's disease flies are causally linked.
Ast, A.
ORCID: https://orcid.org/0000-0002-2312-1257, Roth, L., Brusendorf, L., Schindler, F.
ORCID: https://orcid.org/0000-0002-3320-8284, Ammar, O.W.M.
ORCID: https://orcid.org/0009-0003-5341-4434, Berberich, S., Edel, J., Bonsor, M., Georgii, E., Hänig, C.
ORCID: https://orcid.org/0000-0003-1973-7646, Langnick, C., Ivanov, A.
ORCID: https://orcid.org/0000-0002-4824-1925, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632, Piraud, M., Kunz, S.
ORCID: https://orcid.org/0000-0002-0131-3506, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Petzoldt, A.G. and Wanker, E.E.
ORCID: https://orcid.org/0000-0001-8072-1630
bioRxiv
: 2025.02.06.636778.
7 February 2025
Multicenter longitudinal quality assessment of MS-based proteomics in plasma and serum.
Kardell, Oliver, Gronauer, Thomas, von Toerne, Christine, Merl-Pham, Juliane, König, Ann-Christine, Barth, Teresa K., Mergner, Julia, Ludwig, Christina, Tüshaus, Johanna, Giesbertz, Pieter, Breimann, Stephan, Schweizer, Lisa, Müller, Torsten, Kliewer, Georg, Distler, Ute, Gomez-Zepeda, David, Popp, Oliver
ORCID: https://orcid.org/0000-0001-6240-4666, Qin, Di, Teupser, Daniel, Cox, Jürgen, Imhof, Axel, Küster, Bernhard, Lichtenthaler, Stefan F., Krijgsveld, Jeroen, Tenzer, Stefan, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Coscia, Fabian
ORCID: https://orcid.org/0000-0002-2244-5081 and Hauck, Stefanie M.
[Dataset]
7 February 2025
Cytokine-armed vaccinia virus promotes cytotoxicity toward pancreatic carcinoma cells via activation of human intermediary CD56(dim)CD16(dim) natural killer cells.
Wang, R., Hu, M., Lozzi, I., Jin, C.Z.J., Ma, D., Splith, K., Mengwasser, J., Wolf, V., Feldbrügge, L., Tang, P., Timmermann, L., Hillebrandt, K.H., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Hilfenhaus, G.
ORCID: https://orcid.org/0000-0001-8764-077X, Neumann, C.C.M., Kammertoens, T.
ORCID: https://orcid.org/0000-0003-3309-5141, Pratschke, J., Malinka, T., Sauer, I.M., Noessner, E., Guo, Z.S. and Felsenstein, M.
ORCID: https://orcid.org/0000-0003-3146-8717
International Journal of Cancer 156
(3): 638-651.
1 February 2025
High Ano1 expression as key driver of resistance to radiation and cisplatin in HPV-negative head and neck squamous cell carcinoma.
Bourdier, S., Fisch, A.S., Alp, K.M.
ORCID: https://orcid.org/0000-0001-9919-9838, Das, R., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Tinhofer, I.
Scientific Reports 15
(1): 1555.
10 January 2025
2024
Hyperphenylalaninemia and serotonin deficiency in Dnajc12-deficient mice.
Cao, Y.
ORCID: https://orcid.org/0000-0003-0440-3977, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Milani, N.
ORCID: https://orcid.org/0000-0001-7510-7986, Qadri, F.
ORCID: https://orcid.org/0000-0002-8500-489X, Kühn, R.
ORCID: https://orcid.org/0000-0003-1694-9803, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Bader, M.
ORCID: https://orcid.org/0000-0003-4780-4164 and Alenina, N.
ORCID: https://orcid.org/0000-0002-6071-5433
Communications Biology 7
(1): 1641.
18 December 2024
A point-of-research decision in synovial tissue engineering: Mesenchymal stromal cells, tissue derived fibroblast or CTGF-mediated mesenchymal-to-fibroblast transition.
Damerau, A., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Buttgereit, F. and Gaber, T.
European Journal of Cell Biology 103
(4): 151455.
December 2024
Proteomic insights into circadian transcription regulation: novel E-box interactors revealed by proximity labeling.
Torres, M., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Marks, C.G., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Kramer, A.
Genes & Development 38
(21-24): 1020-1032.
November 2024
Quantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core network.
Klinger, B.
ORCID: https://orcid.org/0000-0003-0242-1506, Rausch, I., Siebert, A.
ORCID: https://orcid.org/0000-0001-6588-8547, Kutz, H., Kruse, V., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Kieser, A.
ORCID: https://orcid.org/0000-0003-0783-1950, Blüthgen, N.
ORCID: https://orcid.org/0000-0002-0171-7447 and Kube, D.
ORCID: https://orcid.org/0000-0001-7760-525X
PLoS Computational Biology 20
(10): e1012488.
1 October 2024
Combining Data Independent Acquisition with spike-in SILAC (DIA-SiS) improves proteome coverage and quantification.
Welter, A.S.
ORCID: https://orcid.org/0009-0003-9846-3889, Gerwien, M.
ORCID: https://orcid.org/0000-0002-2884-4155, Kerridge, R., Alp, K.M.
ORCID: https://orcid.org/0000-0001-9919-9838, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751
Molecular & Cellular Proteomics 23
(10): 100839.
October 2024
Antibodies and complement are key drivers of thrombosis.
Stark, K., Kilani, B., Stockhausen, S., Busse, J., Schubert, I., Tran, T.D., Gaertner, F., Leunig, A., Pekayvaz, K., Nicolai, L., Fumagalli, V., Stermann, J., Stephan, F., David, C., Müller, M.B., Heyman, B., Lux, A., da Palma Guerreiro, A., Frenzel, L.P., Schmidt, C.Q., Dopler, A., Moser, M., Chandraratne, Sue, von Brühl, M.L., Lorenz, M., Korff, T., Rudelius, M., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Nimmerjahn, F., Iannacone, M., Sperandio, M., Engelmann, B., Verschoor, A. and Massberg, S.
Immunity 57
(9): 2140-2156.e10.
10 September 2024
High serum prevalence of autoreactive IgG antibodies against peripheral nerve structures in patients with neurological post-COVID-19 vaccination syndrome.
Arlt, F.A., Breuer, A., Trampenau, E., Boesl, F., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Sánchez-Sendín, E., Nasouti, M., Mayrhofer, M., Blüthner, M., Endres, M., Prüss, H. and Franke, C.
Frontiers in Immunology 15
: 1404800.
2 August 2024
Immunosuppression with cyclosporine versus tacrolimus shows distinctive nephrotoxicity profiles within renal compartments.
Demirci, H.
ORCID: https://orcid.org/0000-0001-7730-9653, Popovic, S.
ORCID: https://orcid.org/0000-0002-3121-7953, Dittmayer, C., Yilmaz, D.E.
ORCID: https://orcid.org/0000-0002-1110-8389, El-Shimy, I.A.
ORCID: https://orcid.org/0000-0003-0587-5140, Mülleder, M., Hinze, C., Su, M., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Osmanodja, B., Paliege, A., Budde, K., Amann, K., Persson, P.B., Mutig, K. and Bachmann, S.
Acta Physiologica 240
(8): e14190.
August 2024
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.
Waltho, A.
ORCID: https://orcid.org/0009-0000-0059-9357, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Lenz, C.
ORCID: https://orcid.org/0009-0000-2261-2823, Pluska, L.
ORCID: https://orcid.org/0000-0002-8669-6533, Lambert, M., Dötsch, V.
ORCID: https://orcid.org/0000-0001-5720-212X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Sommer, T.
ORCID: https://orcid.org/0000-0001-9990-5202
Life Science Alliance 7
(8): e202402740.
August 2024
The proteogenomic landscape of multiple myeloma reveals insights into disease biology and therapeutic opportunities.
Ramberger, E.
ORCID: https://orcid.org/0000-0003-2760-2696, Sapozhnikova, V., Ng, Y.L.D., Dolnik, A., Ziehm, M.
ORCID: https://orcid.org/0000-0001-7074-4054, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Sträng, E., Kull, M., Grünschläger, F.
ORCID: https://orcid.org/0000-0003-0021-6912, Krüger, J.
ORCID: https://orcid.org/0000-0001-5789-4082, Benary, M.
ORCID: https://orcid.org/0000-0002-3067-2030, Müller, S.
ORCID: https://orcid.org/0009-0003-6363-5599, Gao, X., Murgai, A.
ORCID: https://orcid.org/0000-0001-9767-7402, Haji, M., Schmidt, A., Lutz, R., Nogai, A., Braune, J.
ORCID: https://orcid.org/0000-0003-2026-2641, Laue, D.
ORCID: https://orcid.org/0000-0002-7237-9414, Langer, C., Khandanpour, C., Bassermann, F.
ORCID: https://orcid.org/0000-0003-4435-2609, Döhner, H.
ORCID: https://orcid.org/0000-0003-2116-5536, Engelhardt, M.
ORCID: https://orcid.org/0000-0003-0405-1676, Straka, C., Hundemer, M.
ORCID: https://orcid.org/0000-0002-5596-2405, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632, Haas, S.
ORCID: https://orcid.org/0000-0001-9227-2051, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Einsele, H.
ORCID: https://orcid.org/0000-0002-7680-0819, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Knop, S.
ORCID: https://orcid.org/0000-0003-1276-6639, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Krönke, J.
Nature Cancer 5
(8): 1267-1284.
August 2024
Comprehensive characterization of the viscoelastic properties of bovine submaxillary mucin (BSM) hydrogels and the effect of additives.
Rulff, H.
ORCID: https://orcid.org/0000-0002-7803-3668, Schmidt, R.F., Wei, L.F., Fentker, K.
ORCID: https://orcid.org/0009-0005-0437-1049, Kerkhoff, Y., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Mall, M.A., Lauster, D. and Gradzielski, M.
ORCID: https://orcid.org/0000-0002-7262-7115
Biomacromolecules 25
(7): 4014-4029.
8 July 2024
Microglial sex differences in innate high anxiety and modulatory effects of minocycline.
Ugursu, B.
ORCID: https://orcid.org/0000-0002-2488-4141, Sah, A., Sartori, S., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Dunay, I.R., Kettenmann, H.
ORCID: https://orcid.org/0000-0001-8208-0291, Singewald, N. and Wolf, S.A.
ORCID: https://orcid.org/0000-0003-0922-8418
Brain Behavior and Immunity 119
: 465-481.
July 2024
Mechanical strain activates planar cell polarity signaling to coordinate vascular cell dynamics.
Golbach, L., Saha, T., Odenthal-Schnittler, M.
ORCID: https://orcid.org/0000-0001-8467-7585, Lücking, J., Velic, A., Akmeric, E.B.
ORCID: https://orcid.org/0000-0003-4463-8017, Bornhorst, D.
ORCID: https://orcid.org/0000-0003-4084-0250, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Gunawan, F.
ORCID: https://orcid.org/0000-0002-5592-9680, Gerhardt, H.
ORCID: https://orcid.org/0000-0002-3030-0384, Macek, B.
ORCID: https://orcid.org/0000-0002-1206-2458, Trappmann, B.
ORCID: https://orcid.org/0000-0002-6260-4075, Schnittler, H.J.
ORCID: https://orcid.org/0000-0001-6807-3343, Galic, M.
ORCID: https://orcid.org/0000-0002-4493-2542 and Matis, M.
ORCID: https://orcid.org/0000-0003-3972-1983
bioRxiv
: 2024.06.25.600357.
26 June 2024
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes.
Pekayvaz, K.
ORCID: https://orcid.org/0000-0003-4040-650X, Losert, C.
ORCID: https://orcid.org/0000-0002-5997-4702, Knottenberg, V., Gold, C., van Blokland, I.V., Oelen, R.
ORCID: https://orcid.org/0000-0002-5026-6531, Groot, H.E., Benjamins, J.W.
ORCID: https://orcid.org/0000-0002-5701-0539, Brambs, S., Kaiser, R.
ORCID: https://orcid.org/0000-0003-1750-3395, Gottschlich, A.
ORCID: https://orcid.org/0000-0002-2898-4182, Hoffmann, G.V., Eivers, L., Martinez-Navarro, A.
ORCID: https://orcid.org/0000-0003-3893-1719, Bruns, N., Stiller, S., Akgöl, S.
ORCID: https://orcid.org/0000-0002-3154-3214, Yue, K., Polewka, V., Escaig, R., Joppich, M.
ORCID: https://orcid.org/0000-0002-6665-8951, Janjic, A., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Kobold, S.
ORCID: https://orcid.org/0000-0002-5612-4673, Petzold, T., Zimmer, R., Enard, W., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, van der Harst, P., Franke, L.H., van der Wijst, M.G.P.
ORCID: https://orcid.org/0000-0003-1520-3970, Massberg, S.
ORCID: https://orcid.org/0000-0001-7387-3986, Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Nicolai, L.
ORCID: https://orcid.org/0000-0003-0776-5885 and Stark, K.
ORCID: https://orcid.org/0000-0002-5369-8399
Nature Medicine 30
(6): 1696-1710.
June 2024
Ion mobility-tandem mass spectrometry of mucin-type O-glycans.
Bechtella, L.
ORCID: https://orcid.org/0000-0002-7354-3108, Chunsheng, J.
ORCID: https://orcid.org/0000-0002-0229-102X, Fentker, K.
ORCID: https://orcid.org/0009-0005-0437-1049, Ertürk, G.R., Safferthal, M.
ORCID: https://orcid.org/0009-0006-9267-3940, Polewski, Ł.
ORCID: https://orcid.org/0009-0001-9802-2528, Götze, M.
ORCID: https://orcid.org/0000-0003-4001-2324, Graeber, S.Y.
ORCID: https://orcid.org/0000-0002-1666-8924, Vos, G.M., Struwe, W.B.
ORCID: https://orcid.org/0000-0003-0594-226X, Mall, M.A.
ORCID: https://orcid.org/0000-0002-4057-2199, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Karlsson, N.G. and Pagel, K.
ORCID: https://orcid.org/0000-0001-8054-4718
Nature Communications 15
(1): 2611.
23 March 2024
Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment.
Kaiser, R., Gold, C., Joppich, M., Loew, Q., Akhalkatsi, A., Mueller, T.T., Offensperger, F., Droste Zu Senden, A., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, di Fina, L., Knottenberg, V., Martinez-Navarro, A., Eivers, L., Anjum, A., Escaig, R., Bruns, N., Briem, E., Dewender, R., Muraly, A., Akgöl, S., Ferraro, B., Hoeflinger, J.K.L., Polewka, V., Khaled, N.B., Allgeier, J., Tiedt, S., Dichgans, M., Engelmann, B., Enard, W., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Weckbach, L., Zimmer, R., Massberg, S., Stark, K., Nicolai, L. and Pekayvaz, K.
Science Advances 10
(12): eadl1710.
22 March 2024
Mice with renal-specific alterations 1 of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors.
Myszczyszyn, A.
ORCID: https://orcid.org/0009-0006-6152-5451, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Kunz, S.
ORCID: https://orcid.org/0000-0002-0131-3506, Sporbert, A.
ORCID: https://orcid.org/0000-0002-3738-1295, Jung, S., Penning, L.C., Fendler, A.
ORCID: https://orcid.org/0000-0002-7267-0981, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
PLoS ONE 19
(3): e0282938.
21 March 2024
Passenger gene coamplifications create collateral therapeutic vulnerabilities in cancer.
Bei, Y.
ORCID: https://orcid.org/0000-0002-2104-8025, Brame, Luca
ORCID: https://orcid.org/0000-0001-5316-2992, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Fritsche-Guenther, R.
ORCID: https://orcid.org/0000-0002-6965-0226, Kunz, S.
ORCID: https://orcid.org/0000-0002-0131-3506, Bhattacharya, A.
ORCID: https://orcid.org/0000-0003-3733-7670, Rusu, M.C.
ORCID: https://orcid.org/0000-0002-8369-3580, Gürgen, D.
ORCID: https://orcid.org/0000-0001-9241-6537, Dubois, F.P.B.
ORCID: https://orcid.org/0000-0002-7654-6208, Köppke, J.K.C.
ORCID: https://orcid.org/0000-0002-1293-7250, Proba, J.
ORCID: https://orcid.org/0009-0006-8293-1248, Wittstruck, N.
ORCID: https://orcid.org/0009-0000-4378-3226, Sidorova, O.A.
ORCID: https://orcid.org/0009-0004-1459-1662, Chamorro González, R.
ORCID: https://orcid.org/0000-0002-5653-7259, Dorado Garcia, H.
ORCID: https://orcid.org/0000-0002-2578-3350, Brückner, L.
ORCID: https://orcid.org/0000-0002-6155-2277, Xu, R.
ORCID: https://orcid.org/0000-0002-5618-246X, Giurgiu, M.
ORCID: https://orcid.org/0000-0001-5007-7442, Rodriguez-Fos, E.
ORCID: https://orcid.org/0000-0002-2555-0178, Yu, Q.
ORCID: https://orcid.org/0000-0002-2151-9624, Spanjaard, B.
ORCID: https://orcid.org/0000-0003-1309-8839, Koche, R.P.
ORCID: https://orcid.org/0000-0002-6820-5083, Schmitt, C.A.
ORCID: https://orcid.org/0000-0002-4731-2226, Schulte, J.H.
ORCID: https://orcid.org/0000-0003-0671-1201, Eggert, A.
ORCID: https://orcid.org/0000-0003-3476-8184, Haase, K.
ORCID: https://orcid.org/0000-0002-0944-5618, Kirwan, J.
ORCID: https://orcid.org/0000-0002-5423-1651, Hagemann, A.I.
ORCID: https://orcid.org/0000-0001-5491-4607, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Dörr, J.R.
ORCID: https://orcid.org/0000-0002-4927-6548 and Henssen, A.G.
ORCID: https://orcid.org/0000-0003-1534-778X
Cancer Discovery 14
(3): 492-507.
1 March 2024
Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection.
Sun, G.
ORCID: https://orcid.org/0000-0001-7549-7304, Kropp, K.A.
ORCID: https://orcid.org/0000-0001-8505-3440, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Plückebaum, N.
ORCID: https://orcid.org/0000-0002-9788-7335, Selich, A., Serrero, M., Dhingra, A., Cabrera, J.R., Ritter, B., Bauerfeind, R., Wyler, E.
ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M.
ORCID: https://orcid.org/0000-0002-1075-8734, Schambach, A., Sodeik, B.
ORCID: https://orcid.org/0000-0003-4650-3036, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Viejo-Borbolla, A.
ORCID: https://orcid.org/0000-0001-6395-4010
mBio 15
(2): e0330823.
14 February 2024
Targeted proteomics reveals quantitative differences in low-abundance glycosyltransferases of patients with congenital disorders of glycosylation.
Sakson, R.
ORCID: https://orcid.org/0000-0002-9698-0773, Beedgen, L., Bernhard, P.
ORCID: https://orcid.org/0000-0003-1593-9769, Alp, K.M.
ORCID: https://orcid.org/0000-0001-9919-9838, Lübbehusen, N., Röth, R., Niesler, B., Luzarowski, M., Shevchuk, O.
ORCID: https://orcid.org/0000-0003-1150-7344, Mayer, M.P., Thiel, C. and Ruppert, T.
ORCID: https://orcid.org/0000-0001-9152-2266
International Journal of Molecular Sciences 25
(2): 1191.
18 January 2024
The proteomic composition and organization of constitutive heterochromatin in mouse tissues.
Schmidt, A., Zhang, H., Schmitt, S., Rausch, C., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Chen, J., Cmarko, D.
ORCID: https://orcid.org/0000-0002-7467-8565, Butter, F., Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Lermyte, F.
ORCID: https://orcid.org/0000-0001-7371-4475 and Cardoso, M.C.
ORCID: https://orcid.org/0000-0001-8427-8859
Cells 13
(2): 139.
11 January 2024
TTF-1 status in early-stage lung adenocarcinoma is an independent predictor of relapse and survival superior to tumor grading.
Schallenberg, S., Dernbach, G., Dragomir, M.P., Schlachtenberger, G., Boschung, K., Friedrich, C.
ORCID: https://orcid.org/0000-0002-5586-1989, Standvoss, K.
ORCID: https://orcid.org/0000-0002-5739-6726, Ruff, L.
ORCID: https://orcid.org/0000-0002-9707-297X, Anders, P., Grohé, C., Randerath, W., Merkelbach-Bruse, S., Quaas, A., Heldwein, M., Keilholz, U., Hekmat, J.K., Rückert, C., Büttner, R.
ORCID: https://orcid.org/0000-0001-8806-4786, Horst, D., Klauschen, F. and Frost, N.
ORCID: https://orcid.org/0000-0001-7452-7129
European Journal of Cancer 197
: 113474.
January 2024
2023
Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery.
Wang, Z., Shaabani, S.
ORCID: https://orcid.org/0000-0001-5546-7140, Gao, X., Ng, Y.L.D.
ORCID: https://orcid.org/0000-0001-7959-454X, Sapozhnikova, V., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Krönke, J.
ORCID: https://orcid.org/0000-0002-4649-0506 and Dömling, A.
ORCID: https://orcid.org/0000-0002-9923-8873
Nature Communications 14
(1): 8437.
19 December 2023
Using PrISMa to reveal the interactome of the human claudins family.
Perez-Hernandez, D.
ORCID: https://orcid.org/0000-0003-0266-9050, Suarez-Artiles, L.
ORCID: https://orcid.org/0000-0001-7991-5446, Jones, M.S.O. and Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623
STAR Protocols 4
(4): 102549.
15 December 2023
Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.
Kühnisch, J.
ORCID: https://orcid.org/0000-0003-4744-5421, Theisen, S., Dartsch, J.
ORCID: https://orcid.org/0000-0002-7947-2881, Fritsche-Guenther, R.
ORCID: https://orcid.org/0000-0002-6965-0226, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Obermayer, B.
ORCID: https://orcid.org/0000-0002-9116-630X, Bauer, A., Kahlert, A.K., Rothe, M.
ORCID: https://orcid.org/0000-0002-6813-4705, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Kirwan, J.A.
ORCID: https://orcid.org/0000-0002-5423-1651, Berndt, N., MacRae, C.A., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223 and Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912
Cardiovascular Research 119
(18): 2902-2916.
December 2023
Leveraging ligand affinity and properties: discovery of novel benzamide-type cereblon binders for the design of PROTACs.
Steinebach, C.
ORCID: https://orcid.org/0000-0001-5638-1955, Bricelj, A., Murgai, A., Sosič, I.
ORCID: https://orcid.org/0000-0002-3370-4587, Bischof, L., Ng, Y.L.D., Heim, C., Maiwald, S.
ORCID: https://orcid.org/0000-0002-7235-2748, Proj, M.
ORCID: https://orcid.org/0000-0003-4043-9686, Voget, R., Feller, F.
ORCID: https://orcid.org/0009-0007-1820-772X, Košmrlj, J.
ORCID: https://orcid.org/0000-0002-3533-0419, Sapozhnikova, V., Schmidt, A., Zuleeg, M.R., Lemnitzer, P., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Hansen, F.K.
ORCID: https://orcid.org/0000-0001-9765-5975, Gütschow, M.
ORCID: https://orcid.org/0000-0002-9376-7897, Krönke, J. and Hartmann, M.D.
ORCID: https://orcid.org/0000-0001-6937-5677
Journal of Medicinal Chemistry 66
(21): 14513-14543.
9 November 2023
Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Briest, F.
ORCID: https://orcid.org/0000-0001-5969-9467, Noerenberg, D., Hennch, C.
ORCID: https://orcid.org/0000-0003-4104-5531, Yoshida, K.
ORCID: https://orcid.org/0000-0003-4612-2778, Hablesreiter, R.
ORCID: https://orcid.org/0000-0002-4586-932X, Nimo, J.
ORCID: https://orcid.org/0000-0002-1565-7799, Sasca, D.
ORCID: https://orcid.org/0000-0003-0330-7959, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mansouri, L., Inoue, Y., Wiegand, L.
ORCID: https://orcid.org/0000-0002-9917-7396, Staiger, A.M.
ORCID: https://orcid.org/0000-0002-5896-3200, Casadei, B., Korkolopoulou, P., Weiner, J.
ORCID: https://orcid.org/0000-0003-1438-7819, Lopez-Guillermo, A., Warth, A., Schneider, T., Nagy, Á.
ORCID: https://orcid.org/0000-0001-6118-0365, Klapper, W., Hummel, M.
ORCID: https://orcid.org/0000-0001-6717-605X, Kanellis, G., Anagnostopoulos, I.
ORCID: https://orcid.org/0000-0002-5043-6043, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Rosenquist, R.
ORCID: https://orcid.org/0000-0002-0211-8788, Vassilakopoulos, T.P., Ott, G., Ogawa, S.
ORCID: https://orcid.org/0000-0002-7778-5374 and Damm, F.
ORCID: https://orcid.org/0000-0001-5553-1173
Leukemia 37
(11): 2237-2249.
November 2023
Longitudinal effects of elexacaftor/tezacaftor/ivacaftor on sputum viscoelastic properties, airway infection and inflammation in patients with cystic fibrosis.
Schaupp, L.
ORCID: https://orcid.org/0000-0003-1383-3821, Addante, A., Völler, M., Fentker, K.
ORCID: https://orcid.org/0009-0005-0437-1049, Kuppe, A., Bardua, M., Duerr, J.
ORCID: https://orcid.org/0000-0002-4862-9487, Piehler, L., Röhmel, J.
ORCID: https://orcid.org/0000-0002-1535-8852, Thee, S.
ORCID: https://orcid.org/0000-0001-9090-7869, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Ziehm, M.
ORCID: https://orcid.org/0000-0001-7074-4054, Lauster, D., Haag, R., Gradzielski, M., Stahl, M.
ORCID: https://orcid.org/0000-0001-6941-8315, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Boutin, S., Graeber, S.Y.
ORCID: https://orcid.org/0000-0002-1666-8924 and Mall, M.A.
ORCID: https://orcid.org/0000-0002-4057-2199
European Respiratory Journal 62
(2): 2202153.
1 August 2023
A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Boeddrich, A.
ORCID: https://orcid.org/0000-0001-9118-050X, Haenig, C.
ORCID: https://orcid.org/0000-0003-1973-7646, Neuendorf, N., Blanc, E.
ORCID: https://orcid.org/0000-0002-4369-0254, Ivanov, A.
ORCID: https://orcid.org/0000-0002-4824-1925, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Schleumann, P., Bayraktaroğlu, I., Richter, M.
ORCID: https://orcid.org/0000-0002-5339-0781, Molenda, C.M.
ORCID: https://orcid.org/0000-0003-0771-405X, Sporbert, A.
ORCID: https://orcid.org/0000-0002-3738-1295, Zenkner, M., Schnoegl, S., Suenkel, C.
ORCID: https://orcid.org/0000-0002-5326-6043, Schneider, L.S., Rybak-Wolf, A.
ORCID: https://orcid.org/0000-0002-1192-5290, Kochnowsky, B., Byrne, L.M., Wild, E.J., Nielsen, J.E., Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Peters, O.
ORCID: https://orcid.org/0000-0003-0568-2998, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632 and Wanker, E.E.
ORCID: https://orcid.org/0000-0001-8072-1630
Genome Medicine 15
(1): 50.
20 July 2023
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.
Fuchs, S.
ORCID: https://orcid.org/0000-0001-9619-4329, Danßmann, C., Klironomos, F., Winkler, A., Fallmann, J.
ORCID: https://orcid.org/0000-0002-4573-9939, Kruetzfeldt, L.M.
ORCID: https://orcid.org/0000-0003-3630-3727, Szymansky, A.
ORCID: https://orcid.org/0000-0003-4797-4526, Naderi, J., Bernhart, S.H.
ORCID: https://orcid.org/0000-0002-5928-9449, Grunewald, L., Helmsauer, K.
ORCID: https://orcid.org/0000-0003-0773-4114, Rodriguez-Fos, E.
ORCID: https://orcid.org/0000-0002-2555-0178, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Astrahantseff, K.
ORCID: https://orcid.org/0000-0002-7872-1997, Suenkel, C.
ORCID: https://orcid.org/0000-0002-5326-6043, Toedling, J.
ORCID: https://orcid.org/0000-0003-1471-1295, Meggetto, F.
ORCID: https://orcid.org/0000-0002-2610-0144, Remke, M.
ORCID: https://orcid.org/0000-0002-9404-9993, Stadler, P.F., Hundsdoerfer, P., Deubzer, H.E.
ORCID: https://orcid.org/0000-0002-6115-4893, Künkele, A.
ORCID: https://orcid.org/0000-0002-8406-5412, Lang, P.
ORCID: https://orcid.org/0000-0001-7737-2142, Fuchs, J., Henssen, A.G.
ORCID: https://orcid.org/0000-0003-1534-778X, Eggert, A.
ORCID: https://orcid.org/0000-0003-3476-8184, Rajewsky, N.
ORCID: https://orcid.org/0000-0002-4785-4332, Hertwig, F.
ORCID: https://orcid.org/0000-0003-4784-6516 and Schulte, J.H.
ORCID: https://orcid.org/0000-0003-0671-1201
Nature Communications 14
(1): 3936.
4 July 2023
Sex-specific microglia state in the neuroligin-4 knock-out mouse model of autism spectrum disorder.
Guneykaya, D.
ORCID: https://orcid.org/0000-0001-5723-0737, Ugursu, B., Logiacco, F.
ORCID: https://orcid.org/0000-0003-4696-2240, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Feiks, M.A., Meyer, N.
ORCID: https://orcid.org/0000-0002-8377-097X, Wendt, S., Semtner, M.
ORCID: https://orcid.org/0000-0001-9379-9023, Cherif, F., Gauthier, C., Madore, C., Yin, Z., Çınar, Ö.
ORCID: https://orcid.org/0000-0001-5297-127X, Arslan, T., Gerevich, Z., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Butovsky, O., Kettenmann, H.
ORCID: https://orcid.org/0000-0001-8208-0291 and Wolf, S.A.
ORCID: https://orcid.org/0000-0003-0922-8418
Brain Behavior and Immunity 111
: 61-75.
July 2023
Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity.
Torcal Garcia, G.
ORCID: https://orcid.org/0000-0002-0843-7296, Kowenz-Leutz, E., Tian, T.V
ORCID: https://orcid.org/0000-0002-9906-0980, Klonizakis, A., Lerner, J., De Andres-Aguayo, L., Sapozhnikova, V., Berenguer, C., Carmona, M.P., Casadesus, M.V., Bulteau, R.
ORCID: https://orcid.org/0000-0002-9128-8809, Francesconi, M., Peiro, S., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Zaret, K., Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X and Graf, T.
ORCID: https://orcid.org/0000-0003-2774-4117
eLife 12
: e83951.
27 June 2023
Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames.
Sandmann, C.L.
ORCID: https://orcid.org/0000-0002-3847-0708, Schulz, J.F.
ORCID: https://orcid.org/0000-0002-8157-2224, Ruiz-Orera, J.
ORCID: https://orcid.org/0000-0002-8317-0034, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Ziehm, M.
ORCID: https://orcid.org/0000-0001-7074-4054, Adami, E.
ORCID: https://orcid.org/0000-0002-1813-6681, Marczenke, M., Christ, A.
ORCID: https://orcid.org/0000-0002-2019-176X, Liebe, N., Greiner, J.
ORCID: https://orcid.org/0009-0002-0811-3440, Schoenenberger, A., Mücke, M.B.
ORCID: https://orcid.org/0000-0002-4957-3307, Liang, N.
ORCID: https://orcid.org/0009-0008-8137-6873, Moritz, R.L., Sun, Z., Deutsch, E.W., Gotthardt, M.
ORCID: https://orcid.org/0000-0003-1788-3172, Mudge, J.M., Prensner, J.R., Willnow, T.E.
ORCID: https://orcid.org/0000-0001-9515-7921, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, van Heesch, S.
ORCID: https://orcid.org/0000-0001-9593-1980 and Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Molecular Cell 83
(6): 994-1011.e18.
16 March 2023
Response to: Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Chheda et al.
Immisch, L.
ORCID: https://orcid.org/0000-0001-5072-8583, Papafotiou, G., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Blankenstein, T.
ORCID: https://orcid.org/0000-0002-3357-4321 and Willimsky, G.
ORCID: https://orcid.org/0000-0002-9693-948X
Journal for ImmunoTherapy of Cancer 11
(3): e006784.
14 March 2023
Neurofibromatosis type 1-dependent alterations in mouse microglia function are not cell-intrinsic.
Logiacco, F.
ORCID: https://orcid.org/0000-0003-4696-2240, Grzegorzek, L.C., Cordell, E.C., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Gutmann, D.H.
ORCID: https://orcid.org/0000-0002-3127-5045, Kettenmann, H.
ORCID: https://orcid.org/0000-0001-8208-0291 and Semtner, M.
ORCID: https://orcid.org/0000-0001-9379-9023
Acta Neuropathologica Communications 11
(1): 36.
9 March 2023
Disease- and sex-specific differences in patients with heart valve disease: a proteome study.
Nordmeyer, S.
ORCID: https://orcid.org/0000-0002-1111-2521, Kraus, M.
ORCID: https://orcid.org/0000-0002-4472-0427, Ziehm, M.
ORCID: https://orcid.org/0000-0001-7074-4054, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Schafstedde, M.
ORCID: https://orcid.org/0000-0002-4860-8010, Kelm, M., Niquet, S., Stephen, M.M., Baczko, I.
ORCID: https://orcid.org/0000-0002-9588-0797, Knosalla, C.
ORCID: https://orcid.org/0000-0002-8127-5019, Schapranow, M.P.
ORCID: https://orcid.org/0000-0001-6601-2942, Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Gotthardt, M.
ORCID: https://orcid.org/0000-0003-1788-3172, Falcke, M.
ORCID: https://orcid.org/0000-0001-7137-1114, Regitz-Zagrosek, V., Kuehne, T. and Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X
Life Science Alliance 6
(3): e202201411.
March 2023
Massively parallel identification of mRNA localization elements in primary cortical neurons.
Mendonsa, S.
ORCID: https://orcid.org/0000-0001-9814-6662, von Kügelgen, N.
ORCID: https://orcid.org/0000-0001-8116-9032, Dantsuji, S., Ron, M., Breimann, L.
ORCID: https://orcid.org/0000-0001-7702-5749, Baranovskii, A.
ORCID: https://orcid.org/0000-0001-7217-3881, Lödige, I., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Fischer, M., Zerna, N., Bujanic, L., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Ulitsky, I.
ORCID: https://orcid.org/0000-0003-0555-6561 and Chekulaeva, M.
ORCID: https://orcid.org/0000-0002-6868-7887
Nature Neuroscience 26
(3): 394-405.
March 2023
SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma.
Heynen, G.J.J.E., Baumgartner, F.
ORCID: https://orcid.org/0000-0003-0768-1956, Heider, M., Patra, U., Holz, M., Braune, J., Kaiser, M., Schäffer, I., Bamopoulos, S.A., Ramberger, E.
ORCID: https://orcid.org/0000-0003-2760-2696, Murgai, A., Ng, Y.L.D., Demel, U.M.
ORCID: https://orcid.org/0000-0002-6480-4185, Laue, D., Liebig, S., Krüger, J., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Nogai, A., Schick, M.
ORCID: https://orcid.org/0009-0003-8626-0611, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Müller, S., Bassermann, F., Krönke, J., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958 and Wirth, M.
Blood Advances 7
(4): 469-481.
28 February 2023
Small molecule specifically inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation.
Jordan, P., Costa, A., Specker, E.
ORCID: https://orcid.org/0000-0002-9471-9520, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Volkamer, A.
ORCID: https://orcid.org/0000-0002-3760-580X, Piske, R., Obrusnik, T., Kleissle, S., Stuke, K., Rex, A.
ORCID: https://orcid.org/0000-0003-3924-956X, Neuenschwander, M.
ORCID: https://orcid.org/0000-0002-3114-7975, von Kries, J.P.
ORCID: https://orcid.org/0000-0003-4716-4988, Nazare, M.
ORCID: https://orcid.org/0000-0002-1602-2330, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Kettenmann, H.
ORCID: https://orcid.org/0000-0001-8208-0291 and Wolf, S.A.
ORCID: https://orcid.org/0000-0003-0922-8418
PLoS ONE 18
(2): e0278325.
6 February 2023
Replicative aging impedes stress-induced assembly of a key human protein disaggregase.
Mathangasinghe, Y.
ORCID: https://orcid.org/0000-0003-4641-5642, Alberts, N., Rosado, C.J., Cox, D.
ORCID: https://orcid.org/0000-0002-5345-8360, Payne, N.L., Ormsby, A.R., Alp, K.M.
ORCID: https://orcid.org/0000-0001-9919-9838, Sakson, R.
ORCID: https://orcid.org/0000-0002-9698-0773, Uthishtran, S.
ORCID: https://orcid.org/0000-0001-8538-3482, Ruppert, T.
ORCID: https://orcid.org/0000-0001-9152-2266, Arumugam, S.
ORCID: https://orcid.org/0000-0001-6733-4679, Hatters, D.M., Kampinga, H.H.
ORCID: https://orcid.org/0000-0002-8966-8466 and Nillegoda, N.B.
ORCID: https://orcid.org/0000-0002-9980-3991
bioRxiv
: 2022.06.25.497591v2.
8 January 2023
A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.
Xiong, E., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Salomon, C.
ORCID: https://orcid.org/0009-0000-6723-6497, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Kocks, C.
ORCID: https://orcid.org/0000-0003-1749-3334, Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370 and Chu, V.T.
ORCID: https://orcid.org/0000-0003-1327-8696
Frontiers in Immunology 13
: 1083119.
5 January 2023
2022
Protective alpha1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation.
Ebert, M.J.
ORCID: https://orcid.org/0000-0003-1512-7429, Jerke, U., Eulenberg-Gustavus, C.
ORCID: https://orcid.org/0000-0002-2425-2275, Kling, L.
ORCID: https://orcid.org/0000-0001-7894-6187, Jenne, D.E.
ORCID: https://orcid.org/0000-0002-1125-9144, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Bieringer, M.
ORCID: https://orcid.org/0000-0002-5561-3635, Elitok, S., Eckardt, K.U.
ORCID: https://orcid.org/0000-0003-3823-0920, Schreiber, A.
ORCID: https://orcid.org/0000-0003-1244-6379, Salama, A.D.
ORCID: https://orcid.org/0000-0002-9255-9092 and Kettritz, R.
ORCID: https://orcid.org/0000-0001-5821-6718
Journal of Clinical Investigation 132
(23): e160089.
1 December 2022
DNA methylation-based classification of sinonasal tumors.
Jurmeister, P., Glöß, S., Roller, R., Leitheiser, M., Schmid, S., Mochmann, L.H., Payá Capilla, E., Fritz, R., Dittmayer, C., Friedrich, C., Thieme, A., Keyl, P., Jarosch, A., Schallenberg, S., Bläker, H., Hoffmann, I., Vollbrecht, C., Lehmann, A., Hummel, M., Heim, D., Haji, M., Harter, P., Englert, B., Frank, S., Hench, J., Paulus, W., Hasselblatt, M., Hartmann, W., Dohmen, H., Keber, U., Jank, P., Denkert, C., Stadelmann, C., Bremmer, F., Richter, A., Wefers, A., Ribbat-Idel, J., Perner, S., Idel, C., Chiariotti, L., Della Monica, R., Marinelli, A., Schüller, U., Bockmayr, M., Liu, J., Lund, V.J., Forster, M., Lechner, M., Lorenzo-Guerra, S.L., Hermsen, M., Johann, P.D., Agaimy, A., Seegerer, P., Koch, A., Heppner, F., Pfister, S.M., Jones, D.T.W., Sill, M., von Deimling, A., Snuderl, M., Müller, K.R., Forgó, E., Howitt, B.E., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Klauschen, F. and Capper, D.
Nature Communications 13
(1): 7148.
28 November 2022
Pan-claudin family interactome analysis reveals shared and specific interactions.
Suarez Artiles, L.
ORCID: https://orcid.org/0000-0001-7991-5446, Breiderhoff, T.
ORCID: https://orcid.org/0000-0002-1676-7498, Girardello, R., Gonschior, H., Rodius, S., Lesur, A., Reimer, U., Ramberger, E.
ORCID: https://orcid.org/0000-0003-2760-2696, Perez-Hernandez, D.
ORCID: https://orcid.org/0000-0003-0266-9050, Müller, D., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623
Cell Reports 41
(6): 111588.
8 November 2022
Immune phenotypes and target antigens of clonally expanded bone marrow T cells in treatment-naïve multiple myeloma.
Welters, C.
ORCID: https://orcid.org/0000-0002-3098-9003, Lammoglia Cobo, M.F.
ORCID: https://orcid.org/0000-0002-0369-0364, Stein, C.A.
ORCID: https://orcid.org/0000-0002-7892-8007, Hsu, M.T.
ORCID: https://orcid.org/0000-0002-5862-4305, Ben Hamza, A.
ORCID: https://orcid.org/0000-0003-3021-7406, Penter, L.
ORCID: https://orcid.org/0000-0002-9060-0207, Chen, X.
ORCID: https://orcid.org/0000-0002-5614-1406, Buccitelli, C.
ORCID: https://orcid.org/0000-0001-5865-4961, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Dietze, K.
ORCID: https://orcid.org/0000-0002-8329-8329, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Moosmann, A.
ORCID: https://orcid.org/0000-0001-8044-5146, Blanc, E.
ORCID: https://orcid.org/0000-0002-4369-0254, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632, Gerbitz, A.
ORCID: https://orcid.org/0000-0002-0105-2086, Strobel, J.
ORCID: https://orcid.org/0000-0002-1117-0350, Hackstein, H.
ORCID: https://orcid.org/0000-0001-9722-8180, Rahn, H.P.
ORCID: https://orcid.org/0000-0002-5233-3937, Dornmair, K.
ORCID: https://orcid.org/0000-0003-0342-5373, Blankenstein, T.
ORCID: https://orcid.org/0000-0002-3357-4321 and Hansmann, L.
ORCID: https://orcid.org/0000-0003-3790-0128
Cancer Immunology Research 10
(11): 1407-1419.
1 November 2022
Serum dihydrotestosterone is associated with adverse myocardial remodeling in patients with aortic valve stenosis before and after aortic valve replacement.
Schafstedde, M.
ORCID: https://orcid.org/0000-0002-4860-8010, Nordmeyer, J., Berger, F.
ORCID: https://orcid.org/0000-0001-7881-1557, Knosalla, C., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Regitz-Zagrosek, V.
ORCID: https://orcid.org/0000-0002-3566-3467, Kuehne, T., Kraus, M.
ORCID: https://orcid.org/0000-0002-4472-0427 and Nordmeyer, S.
ORCID: https://orcid.org/0000-0002-1111-2521
American Journal of Physiology Heart and Circulatory Physiology 323
(5): H949-H957.
November 2022
The SCF/KIT axis in human mast cells: capicua acts as potent KIT repressor and ERK predominates PI3K.
Franke, K., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Zuberbier, T. and Babina, M.
Allergy 77
(11): 3337-3349.
November 2022
Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation.
Ortiz-Zapater, E.
ORCID: https://orcid.org/0000-0002-7437-4772, Bagley, D.C., Hernandez, V.L., Roberts, L.B.
ORCID: https://orcid.org/0000-0003-1143-304X, Maguire, T.J.A.
ORCID: https://orcid.org/0000-0003-1034-4926, Voss, F., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Peset-Martin, I., Woszczek, G.
ORCID: https://orcid.org/0000-0003-0675-085X, Rosenblatt, J.
ORCID: https://orcid.org/0000-0001-9460-5868, Gotthardt, M.
ORCID: https://orcid.org/0000-0003-1788-3172, Santis, G. and Parsons, M.
ORCID: https://orcid.org/0000-0002-2021-8379
Nature Communications 13
(1): 6407.
27 October 2022
H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2(+) patients with diffuse midline glioma.
Immisch, L., Papafotiou, G., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Blankenstein, T.
ORCID: https://orcid.org/0000-0002-3357-4321 and Willimsky, G.
ORCID: https://orcid.org/0000-0002-9693-948X
Journal for ImmunoTherapy of Cancer 10
(10): e005535.
27 October 2022
A member of the tryptophan-rich protein family is required for efficient sequestration of Plasmodium berghei schizonts.
Gabelich, J.A., Grützke, J., Kirscht, F., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Matz, J.M., Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Rug, M. and Ingmundson, A.
ORCID: https://orcid.org/0000-0002-3277-8162
PLoS Pathogens 18
(9): e1010846.
20 September 2022
Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells.
Pardo, M., Offer, S., Hartner, E., Di Bucchianico, S., Bisig, C., Bauer, S., Pantzke, J., Zimmermann, E.J., Cao, X., Binder, S., Kuhn, E., Huber, A., Jeong, S., Käfer, U., Schneider, E., Mesceriakovas, A., Bendl, J., Brejcha, R., Buchholz, A., Gat, D., Hohaus, T., Rastak, N., Karg, E., Jakobi, G., Kalberer, M., Kanashova, T., Hu, Y., Ogris, C., Marsico, A., Theis, F., Shalit, T., Gröger, T., Rüger, C.P., Oeder, S., Orasche, J., Paul, A., Ziehm, T., Zhang, Z.H., Adam, T., Sippula, O., Sklorz, M., Schnelle-Kreis, J., Czech, H., Kiendler-Scharr, A., Zimmermann, R. and Rudich, Y.
Environment International 166
: 107366.
August 2022
Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Dorado Garcia, H.
ORCID: https://orcid.org/0000-0002-2578-3350, Pusch, F.
ORCID: https://orcid.org/0000-0002-7152-080X, Bei, Y.
ORCID: https://orcid.org/0000-0002-2104-8025, von Stebut, J.
ORCID: https://orcid.org/0000-0001-9811-445X, Ibáñez, G., Guillan, K., Imami, K.
ORCID: https://orcid.org/0000-0002-7451-4982, Gürgen, D.
ORCID: https://orcid.org/0000-0001-9241-6537, Rolff, J., Helmsauer, K.
ORCID: https://orcid.org/0000-0003-0773-4114, Meyer-Liesener, S., Timme, N., Bardinet, V., Chamorro González, R.
ORCID: https://orcid.org/0000-0002-5653-7259, MacArthur, I.C.
ORCID: https://orcid.org/0000-0003-1718-1349, Chen, C.Y.
ORCID: https://orcid.org/0000-0002-1579-024X, Schulz, J., Wengner, A.M.
ORCID: https://orcid.org/0009-0009-5772-1945, Furth, C., Lala, B., Eggert, A.
ORCID: https://orcid.org/0000-0003-3476-8184, Seifert, G., Hundsoerfer, P., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751, Lissat, A., Dubois, F.
ORCID: https://orcid.org/0000-0002-7654-6208, Horst, D., Schulte, J.H.
ORCID: https://orcid.org/0000-0003-0671-1201, Spuler, S.
ORCID: https://orcid.org/0000-0002-0155-1117, You, D., Dela Cruz, F., Kung, A.L.
ORCID: https://orcid.org/0000-0002-9091-488X, Haase, K.
ORCID: https://orcid.org/0000-0002-0944-5618, Di Virgilio, M.
ORCID: https://orcid.org/0000-0001-5189-0793, Scheer, M., Ortiz, M.V. and Henssen, A.G.
ORCID: https://orcid.org/0000-0003-1534-778X
Nature Communications 13
(1): 4297.
25 July 2022
Metabolic reprogramming of synovial fibroblasts in osteoarthritis by inhibition of pathologically overexpressed pyruvate dehydrogenase kinases.
Damerau, A., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Pfeiffenberger, M., Ehlers, L.
ORCID: https://orcid.org/0000-0001-8737-001X, Do Nguyen, D.H., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Bartek, B., Maleitzke, T.
ORCID: https://orcid.org/0000-0003-2924-7384, Palmowski, Y., Hardt, S., Winkler, T., Buttgereit, F. and Gaber, T.
ORCID: https://orcid.org/0000-0002-6675-3895
Metabolic Engineering 72
: 116-132.
July 2022
SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics.
Baytek, G.
ORCID: https://orcid.org/0000-0001-9731-9461, Blume, A.
ORCID: https://orcid.org/0000-0003-3045-8234, Demirel, F.G., Bulut, S., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Tursun, B.
ORCID: https://orcid.org/0000-0001-7293-8629
Biotechniques 73
(1): 5-17.
June 2022
The anti-glucocorticoid receptor antibody clone 5E4: raising awareness of unspecific antibody binding.
Ehlers, L.
ORCID: https://orcid.org/0000-0001-8737-001X, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Strehl, C., Buttgereit, F. and Gaber, T.
ORCID: https://orcid.org/0000-0002-6675-3895
International Journal of Molecular Sciences 23
(9): 5049.
2 May 2022
Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation.
Baytek, G.
ORCID: https://orcid.org/0000-0001-9731-9461, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Tursun, B.
ORCID: https://orcid.org/0000-0001-7293-8629
Biotechniques 72
(5): 175-184.
May 2022
Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
Balasubramanian, S.
ORCID: https://orcid.org/0000-0003-1830-5737, Andreani, M.
ORCID: https://orcid.org/0000-0003-1426-5854, Goncalves Andrade, J., Saha, T., Sundaravinayagam, D.
ORCID: https://orcid.org/0000-0003-0717-7530, Garzón, J., Zhang, W., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Hiraga, S.
ORCID: https://orcid.org/0000-0002-8722-3869, Rahjouei, A.
ORCID: https://orcid.org/0000-0003-3973-6333, Rosen, D.B.
ORCID: https://orcid.org/0000-0002-0412-6239, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Chait, B.T., Donaldson, A.D.
ORCID: https://orcid.org/0000-0001-7842-8136 and Di Virgilio, M.
ORCID: https://orcid.org/0000-0001-5189-0793
eLife 11
: e75047.
13 April 2022
The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.
Günes Günsel, G., Conlon, T.M.
ORCID: https://orcid.org/0000-0002-4316-6612, Jeridi, A., Kim, R., Ertüz, Z., Lang, N.J., Ansari, M.
ORCID: https://orcid.org/0000-0002-8819-7965, Novikova, M., Jiang, D.
ORCID: https://orcid.org/0000-0003-0961-2671, Strunz, M., Gaianova, M., Hollauer, C., Gabriel, C., Angelidis, I., Doll, S., Pestoni, J.C., Edelmann, S.L., Kohlhepp, M.S., Guillot, A.
ORCID: https://orcid.org/0000-0002-6002-9986, Bassler, K., Van Eeckhoutte, H.P., Kayalar, Ö.
ORCID: https://orcid.org/0000-0001-9107-2381, Konyalilar, N.
ORCID: https://orcid.org/0000-0003-3693-6508, Kanashova, T., Rodius, S., Ballester-López, C., Genes Robles, C.M., Smirnova, N., Rehberg, M., Agarwal, C., Krikki, I., Piavaux, B., Verleden, S.E., Vanaudenaerde, B., Königshoff, M., Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Bracke, K.R.
ORCID: https://orcid.org/0000-0001-5906-4605, Schultze, J.L., Watz, H., Eickelberg, O., Stoeger, T., Burgstaller, G.
ORCID: https://orcid.org/0000-0002-7121-2567, Tacke, F.
ORCID: https://orcid.org/0000-0001-6206-0226, Heissmeyer, V., Rinkevich, Y.
ORCID: https://orcid.org/0000-0003-3658-0257, Bayram, H.
ORCID: https://orcid.org/0000-0002-5236-766X, Schiller, H.B.
ORCID: https://orcid.org/0000-0001-9498-7034, Conrad, M.
ORCID: https://orcid.org/0000-0003-1140-5612, Schneider, R. and Yildirim, A.Ö.
ORCID: https://orcid.org/0000-0003-1969-480X
Nature Communications 13
(1): 1303.
14 March 2022
Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.
Pekayvaz, K.
ORCID: https://orcid.org/0000-0003-4040-650X, Leunig, A.
ORCID: https://orcid.org/0000-0002-9179-9203, Kaiser, R.
ORCID: https://orcid.org/0000-0003-1750-3395, Joppich, M.
ORCID: https://orcid.org/0000-0002-6665-8951, Brambs, S., Janjic, A.
ORCID: https://orcid.org/0000-0001-7180-5381, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Nixdorf, D.
ORCID: https://orcid.org/0000-0003-1612-9952, Fumagalli, V., Schmidt, N.
ORCID: https://orcid.org/0000-0002-3232-3491, Polewka, V., Anjum, A.
ORCID: https://orcid.org/0000-0002-1976-4102, Knottenberg, V., Eivers, L., Wange, L.E.
ORCID: https://orcid.org/0000-0002-3275-9156, Gold, C., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Muenchhoff, M.
ORCID: https://orcid.org/0000-0001-7016-0470, Hellmuth, J.C.
ORCID: https://orcid.org/0000-0001-8409-3037, Scherer, C.
ORCID: https://orcid.org/0000-0003-2816-6793, Rubio-Acero, R., Eser, T., Deák, F., Puchinger, K., Kuhl, N., Linder, A., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Tomas, L.
ORCID: https://orcid.org/0000-0001-9371-8721, Schulz, C.
ORCID: https://orcid.org/0000-0002-8149-0747, Wieser, A., Enard, W., Kroidl, I., Geldmacher, C., von Bergwelt-Baildon, M., Keppler, O.T., Munschauer, M.
ORCID: https://orcid.org/0000-0001-6143-4548, Iannacone, M.
ORCID: https://orcid.org/0000-0002-9370-2671, Zimmer, R., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Hoelscher, M., Massberg, S.
ORCID: https://orcid.org/0000-0001-7387-3986, Stark, K.
ORCID: https://orcid.org/0000-0002-5369-8399 and Nicolai, L.
ORCID: https://orcid.org/0000-0003-0776-5885
Nature Communications 13
(1): 1018.
23 February 2022
Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng, Y.L.D.
ORCID: https://orcid.org/0000-0001-7959-454X, Ramberger, E.
ORCID: https://orcid.org/0000-0003-2760-2696, Bohl, S.R., Dolnik, A., Steinebach, C.
ORCID: https://orcid.org/0000-0001-5638-1955, Conrad, T., Müller, S., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Kull, M., Haji, M., Gütschow, M., Döhner, H., Walther, W.
ORCID: https://orcid.org/0000-0003-2884-0231, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Krönke, J.
ORCID: https://orcid.org/0000-0002-4649-0506
Nature Communications 13
(1): 1009.
23 February 2022
Effect of atmospheric aging on soot particle toxicity in lung cell models at the air-liquid interface: differential toxicological impacts of biogenic and anthropogenic secondary organic aerosols (SOAs).
Offer, S., Hartner, E., Di Bucchianico, S.
ORCID: https://orcid.org/0000-0002-6396-892X, Bisig, C.
ORCID: https://orcid.org/0000-0001-9981-1409, Bauer, S., Pantzke, J.
ORCID: https://orcid.org/0000-0001-5420-8905, Zimmermann, E.J.
ORCID: https://orcid.org/0000-0002-8766-180X, Cao, X., Binder, S., Kuhn, E., Huber, A., Jeong, S.
ORCID: https://orcid.org/0000-0001-8057-7827, Käfer, U.
ORCID: https://orcid.org/0000-0002-4016-0661, Martens, P.
ORCID: https://orcid.org/0000-0002-5719-872X, Mesceriakovas, A.
ORCID: https://orcid.org/0000-0002-3257-5293, Bendl, J.
ORCID: https://orcid.org/0000-0003-2322-5483, Brejcha, R., Buchholz, A.
ORCID: https://orcid.org/0000-0002-7119-1452, Gat, D.
ORCID: https://orcid.org/0000-0002-0595-4626, Hohaus, T.
ORCID: https://orcid.org/0000-0001-5722-6244, Rastak, N., Jakobi, G., Kalberer, M.
ORCID: https://orcid.org/0000-0001-8885-6556, Kanashova, T., Hu, Y.
ORCID: https://orcid.org/0000-0003-3811-3206, Ogris, C., Marsico, A., Theis, F., Pardo, M.
ORCID: https://orcid.org/0000-0001-6480-1171, Gröger, T., Oeder, S., Orasche, J., Paul, A., Ziehm, T.
ORCID: https://orcid.org/0000-0001-5586-3709, Zhang, Z.H., Adam, T., Sippula, O.
ORCID: https://orcid.org/0000-0002-6981-2694, Sklorz, M., Schnelle-Kreis, J., Czech, H., Kiendler-Scharr, A.
ORCID: https://orcid.org/0000-0003-3166-2253, Rudich, Y.
ORCID: https://orcid.org/0000-0003-3149-0201 and Zimmermann, R.
Environmental Health Perspectives 130
(2): 27003.
3 February 2022
Uncoupling the excitatory amino acid transporter 2 from its C-terminal interactome restores synaptic glutamate clearance at corticostriatal synapses and alleviates mutant huntingtin-induced hypokinesia.
Hirschberg, S., Dvorzhak, A., Rasooli-Nejad, S.M.A., Angelov, S., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Lättig-Tünnemann, G., Harms, C., Schmitz, D.
ORCID: https://orcid.org/0000-0003-2741-5241 and Grantyn, R.
Frontiers in Cellular Neuroscience 15
: 792652.
31 January 2022
Paracrine interleukin 6 induces cerebral remodeling at early stages after unilateral common carotid artery occlusion in mice.
Kuffner, M.T.C., Koch, S.P, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mueller, S., Lips, J., An, J., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Dirnagl, U., Endres, M., Boehm-Sturm, P., Harms, C. and Hoffmann, C.J.
Frontiers in Cardiovascular Medicine 8
: 805095.
27 January 2022
2021
CARDIOKIN1: computational assessment of myocardial metabolic capability in healthy controls and patients with valve diseases.
Berndt, N.
ORCID: https://orcid.org/0000-0001-5594-9940, Eckstein, J.
ORCID: https://orcid.org/0000-0002-6749-0003, Wallach, I.
ORCID: https://orcid.org/0000-0002-4968-6475, Nordmeyer, S.
ORCID: https://orcid.org/0000-0002-1111-2521, Kelm, M.
ORCID: https://orcid.org/0000-0003-4971-0452, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Goubergrits, L.
ORCID: https://orcid.org/0000-0002-1961-3179, Schafstedde, M.
ORCID: https://orcid.org/0000-0002-4860-8010, Hennemuth, A., Kraus, M.
ORCID: https://orcid.org/0000-0002-4472-0427, Grune, T.
ORCID: https://orcid.org/0000-0003-4775-9973, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Kuehne, T. and Holzhütter, H.G.
ORCID: https://orcid.org/0000-0002-5054-6023
Circulation 144
(24): 1926-1939.
14 December 2021
Multiomic characterization of oncogenic signaling mediated by wild-type and mutant RIT1.
Lo, A.
ORCID: https://orcid.org/0000-0001-6128-9846, Holmes, K.
ORCID: https://orcid.org/0000-0001-9645-4709, Kamlapurkar, S., Mundt, F., Moorthi, S., Fung, I., Fereshetian, S., Watson, J.
ORCID: https://orcid.org/0000-0003-2677-3696, Carr, S.A.
ORCID: https://orcid.org/0000-0002-7203-4299, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Berger, A.H.
ORCID: https://orcid.org/0000-0002-6538-2658
Science Signaling 14
(711): eabc4520.
30 November 2021
GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.
Marczenke, M., Sunaga, D.
ORCID: https://orcid.org/0000-0002-6851-9162, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Althaus, I.W., Sauer, S.
ORCID: https://orcid.org/0000-0002-4794-3693, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Christ, A.
ORCID: https://orcid.org/0000-0002-2019-176X, Allen, B.L. and Willnow, T.E.
ORCID: https://orcid.org/0000-0001-9515-7921
Development 148
(21): dev200080.
11 November 2021
Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.
Dahlmann, M.
ORCID: https://orcid.org/0000-0002-0036-5283, Gambara, G.
ORCID: https://orcid.org/0000-0001-8921-2568, Brzezicha, B., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Pachmayr, E., Wedeken, L.
ORCID: https://orcid.org/0000-0003-1061-9459, Pflaume, A., Mokritzkij, M., Gül-Klein, S.
ORCID: https://orcid.org/0000-0003-1013-7126, Brandl, A.
ORCID: https://orcid.org/0000-0003-1990-2584, Schweiger-Eisbacher, C., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Hoffmann, J.
ORCID: https://orcid.org/0000-0003-3880-1658, Keilholz, U.
ORCID: https://orcid.org/0000-0001-6773-9406, Walther, W.
ORCID: https://orcid.org/0000-0003-2360-1370, Regenbrecht, C.
ORCID: https://orcid.org/0000-0001-9494-5977, Rau, B.
ORCID: https://orcid.org/0000-0001-5820-6907 and Stein, U.
ORCID: https://orcid.org/0000-0001-7006-282X
Molecular Cancer 20
(1): 129.
21 October 2021
Self-sustaining interleukin-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19.
Kaiser, R.
ORCID: https://orcid.org/0000-0003-1750-3395, Leunig, A.
ORCID: https://orcid.org/0000-0002-9179-9203, Pekayvaz, K.
ORCID: https://orcid.org/0000-0003-4040-650X, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Joppich, M.
ORCID: https://orcid.org/0000-0002-6665-8951, Polewka, V., Escaig, R., Anjum, A.
ORCID: https://orcid.org/0000-0002-1976-4102, Hoffknecht, M.L.
ORCID: https://orcid.org/0000-0002-5894-0308, Gold, C., Brambs, S., Engel, A., Stockhausen, S., Knottenberg, V., Titova, A., Haji, M., Scherer, C.
ORCID: https://orcid.org/0000-0003-2816-6793, Muenchhoff, M., Hellmuth, J.C., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Schubert, B.
ORCID: https://orcid.org/0000-0003-3412-1102, Hilgendorff, A.
ORCID: https://orcid.org/0000-0002-3725-996X, Schulz, C., Kääb, S.
ORCID: https://orcid.org/0000-0001-8824-3581, Zimmer, R.
ORCID: https://orcid.org/0000-0003-1439-2327, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Massberg, S., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Nicolai, L.
ORCID: https://orcid.org/0000-0003-0776-5885 and Stark, K.
JCI Insight 6
(18): e150862.
22 September 2021
The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Kobelt, D.
ORCID: https://orcid.org/0000-0002-9373-0648, Perez-Hernandez, D.
ORCID: https://orcid.org/0000-0003-0266-9050, Fleuter, C., Dahlmann, M.
ORCID: https://orcid.org/0000-0002-0036-5283, Zincke, F., Smith, J., Migotti, R.
ORCID: https://orcid.org/0000-0001-7183-1424, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Burock, S., Walther, W.
ORCID: https://orcid.org/0000-0003-2884-0231, Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Stein, U.
ORCID: https://orcid.org/0000-0001-7006-282X
Oncogene 40
(34): 5286-5301.
26 August 2021
A universal peptide matrix interactomics approach to disclose motif dependent protein binding.
Ramberger, E.
ORCID: https://orcid.org/0000-0003-2760-2696, Suarez-Artiles, L.
ORCID: https://orcid.org/0000-0001-7991-5446, Perez-Hernandez, D.
ORCID: https://orcid.org/0000-0003-0266-9050, Haji, M., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Reimer, U.
ORCID: https://orcid.org/0000-0002-3375-6889, Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X, Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623 and Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X
Molecular & Cellular Proteomics 20
: 100135.
13 August 2021
Surface AMP deaminase 2 as a novel regulator modifying extracellular adenine nucleotide metabolism.
Ehlers, L.
ORCID: https://orcid.org/0000-0001-8737-001X, Kuppe, A., Damerau, A., Wilantri, S., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Strehl, C., Buttgereit, F. and Gaber, T.
FASEB Journal 35
(7): e21684.
July 2021
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.
Ramberger, E.
ORCID: https://orcid.org/0000-0003-2760-2696, Sapozhnikova, V., Kowenz-Leutz, E., Zimmermann, K., Nicot, N., Nazarov, P.V., Perez-Hernandez, D.
ORCID: https://orcid.org/0000-0003-0266-9050, Reimer, U., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623 and Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X
iScience 24
(6): 102686.
25 June 2021
Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories.
Friedrich, C.
ORCID: https://orcid.org/0000-0002-5586-1989, Schallenberg, S., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Ziehm, M.
ORCID: https://orcid.org/0000-0001-7074-4054, Niquet, S., Haji, M., Beier, C., Neudecker, J., Klauschen, F.
ORCID: https://orcid.org/0000-0002-9131-2389 and Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X
Nature Communications 12
(1): 3576.
11 June 2021
YAP and β-catenin cooperate to drive oncogenesis in basal breast cancer.
Quinn, H.M.
ORCID: https://orcid.org/0000-0002-1336-5709, Vogel, R., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Lan, L., Messerschmidt, C.
ORCID: https://orcid.org/0000-0001-8632-656X, Landshammer, A., Lisek, K.
ORCID: https://orcid.org/0000-0002-2406-8830, Château-Joubert, S., Marangoni, E., Koren, E., Fuchs, Y. and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Cancer Research 81
(8): 2116-2127.
April 2021
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Hartlieb, S.A.
ORCID: https://orcid.org/0000-0003-3746-7010, Sieverling, L.
ORCID: https://orcid.org/0000-0002-0595-4976, Nadler-Holly, M., Ziehm, M.
ORCID: https://orcid.org/0000-0001-7074-4054, Toprak, U.H., Herrmann, C.
ORCID: https://orcid.org/0000-0003-4989-4722, Ishaque, N.
ORCID: https://orcid.org/0000-0002-8426-901X, Okonechnikov, K., Gartlgruber, M., Park, Y.G., Wecht, E.M., Savelyeva, L., Henrich, K.O., Rosswog, C., Fischer, M.
ORCID: https://orcid.org/0000-0003-1363-1242, Hero, B., Jones, D.T.W., Pfaff, E., Witt, O., Pfister, S.M., Volckmann, Ri., Koster, J.
ORCID: https://orcid.org/0000-0002-0890-7585, Kiesel, K., Rippe, K.
ORCID: https://orcid.org/0000-0001-9951-9395, Taschner-Mandl, S.
ORCID: https://orcid.org/0000-0002-1439-5301, Ambros, P., Brors, B.
ORCID: https://orcid.org/0000-0001-5940-3101, Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751, Feuerbach, L.
ORCID: https://orcid.org/0000-0003-1503-437X and Westermann, F.
Nature Communications 12
(1): 1269.
24 February 2021
Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine.
Rivera, M., Fichtner, I., Wulf-Goldenberg, A., Sers, C., Merk, J., Patone, G., Alp, K.M.
ORCID: https://orcid.org/0000-0001-9919-9838, Kanashova, T., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Hoffmann, J.
ORCID: https://orcid.org/0000-0003-3880-1658, Stein, U.
ORCID: https://orcid.org/0000-0001-7006-282X and Walther, W.
ORCID: https://orcid.org/0000-0003-2884-0231
Neoplasia 23
(1): 21-35.
January 2021
2020
USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells.
van den Berk, P., Lancini, C.
ORCID: https://orcid.org/0000-0001-9880-678X, Company, C.
ORCID: https://orcid.org/0000-0002-7975-0642, Serresi, M.
ORCID: https://orcid.org/0000-0001-6839-8658, Sanchez-Bailon, M.P.
ORCID: https://orcid.org/0000-0001-6929-2273, Hulsman, D., Pritchard, C., Song, J.Y., Schmitt, M.J.
ORCID: https://orcid.org/0000-0001-8296-5858, Tanger, E., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Huijbers, I.J., Jacobs, H.
ORCID: https://orcid.org/0000-0001-6227-9850, van Lohuizen, M., Gargiulo, G.
ORCID: https://orcid.org/0000-0001-5414-4251 and Citterio, E.
ORCID: https://orcid.org/0000-0003-2347-3495
Cell Reports 33
(13): 108533.
29 December 2020
B-cell-specific Myd88 L252P expression causes a premalignant gammopathy resembling IgM MGUS.
Schmidt, K., Sack, U., Graf, R.
ORCID: https://orcid.org/0000-0002-5400-9938, Winkler, W.
ORCID: https://orcid.org/0000-0001-8807-9259, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Sommermann, T.
ORCID: https://orcid.org/0000-0003-2899-0256, Kocks, C.
ORCID: https://orcid.org/0000-0003-1749-3334 and Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370
Frontiers in Immunology 11
: 602868.
1 December 2020
Proteomic analysis reveals upregulation of ACE2, the putative SARS-CoV-2 receptor in pressure- but not volume-overloaded human hearts.
Stegbauer, J., Kraus, M., Nordmeyer, S., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Ziehm, M.
ORCID: https://orcid.org/0000-0001-7074-4054, Dommisch, H., Kelle, S., Kelm, M., Baczko, I., Landmesser, U., Tschope, C., Knosalla, C., Falcke, M.
ORCID: https://orcid.org/0000-0001-7137-1114, Schapranow, M.P.
ORCID: https://orcid.org/0000-0001-6601-2942, Regitz-Zagrosek, V., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Kuehne, T.
Hypertension 76
(6): e41-e43.
December 2020
Proteogenomic landscape of breast cancer tumorigenesis and targeted therapy.
Krug, K., Jaehnig, E.J., Satpathy, S., Blumenberg, L., Karpova, A., Anurag, M., Miles, G., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Geffen, Y., Tang, L.C., Heiman, D.I., Cao, S., Maruvka, Y.E., Lei, J.T., Huang, C., Kothadia, R.B., Colaprico, A., Birger, C., Wang, J., Dou, Y., Wen, B., Shi, Z., Liao, Y., Wiznerowicz, M., Wyczalkowski, M.A., Chen, X.S., Kennedy, J.J., Paulovich, A.G., Thiagarajan, M., Kinsinger, C.R., Hiltke, T., Boja, E.S., Mesri, M., Robles, A.I., Rodriguez, H., Westbrook, T.F., Ding, L., Getz, G., Clauser, K.R., Fenyö, D., Ruggles, K.V., Zhang, B., Mani, D.R, Carr, S.A., Ellis, M.J. and Gillette, M.A.
Cell 183
(5): 1436-1456.
25 November 2020
Pairwise stimulations of pathogen-sensing pathways predict immune responses to multi-adjuvant combinations.
Pandey, S., Gruenbaum, A., Kanashova, T., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Cluzel, P. and Chevrier, N.
Cell Systems 11
(5): 495-508.
18 November 2020
Integrated proteomic and glycoproteomic characterization of human high-grade serous ovarian carcinoma.
Hu, Y.
ORCID: https://orcid.org/0000-0002-4629-0985, Pan, J., Shah, P., Ao, M., Thomas, S.N., Liu, Y., Chen, L., Schnaubelt, M., Clark, D.J., Rodriguez, H., Boja, E.S., Hiltke, T., Kinsinger, C.R., Rodland, K.D., Li, Q.K., Qian, J., Zhang, Z., Chan, D.W. and Zhang, H.
Cell Reports 33
(3): 108276.
20 October 2020
Deconstructing sarcomeric structure-function relations in titin-BioID knock-in mice.
Rudolph, F., Fink, C., Hüttemeister, J., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Radke, M.H.
ORCID: https://orcid.org/0000-0003-0112-9917, Lopez Carballo, J.
ORCID: https://orcid.org/0000-0002-7735-7185, Wagner, E., Kohl, T., Lehnart, S.E.
ORCID: https://orcid.org/0000-0002-8115-3513, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Gotthardt, M.
ORCID: https://orcid.org/0000-0003-1788-3172
Nature Communications 11
(1): 3133.
19 June 2020
Influence of wood species on toxicity of log-wood stove combustion aerosols: a parallel animal and air-liquid interface cell exposure study on spruce and pine smoke.
Ihantola, T.
ORCID: https://orcid.org/0000-0003-4182-2011, Di Bucchianico, S., Happo, M., Ihalainen, M., Uski, O., Bauer, S., Kuuspalo, K., Sippula, O., Tissari, J., Oeder, S., Hartikainen, A., Rönkkö, T.J., Martikainen, M.V., Huttunen, K., Vartiainen, P., Suhonen, H., Kortelainen, M., Lamberg, H., Leskinen, A., Sklorz, M., Michalke, B., Dilger, M., Weiss, C., Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Beckers, J., Irmler, M., Buters, J., Candeias, J., Czech, H., Yli-Pirilä, P., Abbaszade, G., Jakobi, G., Orasche, J., Schnelle-Kreis, J., Kanashova, T., Karg, E., Streibel, T., Passig, J., Hakkarainen, H., Jokiniemi, J., Zimmermann, R., Hirvonen, M.R. and Jalava, P.I.
Particle and Fibre Toxicology 17
(1): 27.
15 June 2020
Progression-dependent altered metabolism in osteosarcoma resulting in different nutrient source dependencies.
Fritsche-Guenther, R.
ORCID: https://orcid.org/0000-0002-6965-0226, Gloaguen, Y.
ORCID: https://orcid.org/0000-0003-0493-8592, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Tunn, P.U. and Kirwan, J.A.
ORCID: https://orcid.org/0000-0002-5423-1651
Cancers 12
(6): 1371.
27 May 2020
The VGF-derived peptide TLQP21 impairs purinergic control of chemotaxis and phagocytosis in mouse microglia.
Elmadany, N.
ORCID: https://orcid.org/0000-0001-9038-8368, de Almeida Sassi, F.
ORCID: https://orcid.org/0000-0003-4649-3421, Wendt, S., Logiacco, F.
ORCID: https://orcid.org/0000-0003-4696-2240, Visser, J., Haage, V.
ORCID: https://orcid.org/0000-0001-7569-8421, Perez Hernandez, D.
ORCID: https://orcid.org/0000-0003-0266-9050, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Hambardzumyan, D., Wolf, S.
ORCID: https://orcid.org/0000-0003-0922-8418, Kettenmann, H.
ORCID: https://orcid.org/0000-0001-8208-0291 and Semtner, M.
ORCID: https://orcid.org/0000-0001-9379-9023
Journal of Neuroscience 40
(17): 3320-3331.
22 April 2020
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.
Müller, P.M.
ORCID: https://orcid.org/0000-0001-9056-4114, Rademacher, J., Bagshaw, R.D.
ORCID: https://orcid.org/0000-0001-5013-4291, Wortmann, C., Barth, C., van Unen, J., Alp, K.M.
ORCID: https://orcid.org/0000-0001-9919-9838, Giudice, G., Eccles, R.L.
ORCID: https://orcid.org/0000-0002-8209-5650, Heinrich, L.E., Pascual-Vargas, P., Sanchez-Castro, M., Brandenburg, L., Mbamalu, G., Tucholska, M., Spatt, L., Czajkowski, M.T.
ORCID: https://orcid.org/0000-0002-0122-1943, Welke, R.W., Zhang, S., Nguyen, V., Rrustemi, T.
ORCID: https://orcid.org/0000-0002-9075-103X, Trnka, P., Freitag, K.
ORCID: https://orcid.org/0000-0002-5244-3140, Larsen, B., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Gingras, A.C.
ORCID: https://orcid.org/0000-0002-6090-4437, Roth, F.P.
ORCID: https://orcid.org/0000-0002-6628-649X, Colwill, K.
ORCID: https://orcid.org/0000-0002-8979-1659, Bakal, C.
ORCID: https://orcid.org/0000-0002-0413-6744, Pertz, O.
ORCID: https://orcid.org/0000-0001-8579-4919, Pawson, T., Petsalaki, E.
ORCID: https://orcid.org/0000-0002-8294-2995 and Rocks, O.
ORCID: https://orcid.org/0000-0001-6349-9193
Nature Cell Biology 22
(4): 498-511.
April 2020
Cyclin-dependent kinase 18 controls trafficking of
aquaporin-2 and its abundance through ubiquitin
ligase STUB1, which functions as an AKAP.
Dema, A., Faust, D., Lazarow, K., Wippich, M., Neuenschwander, M.
ORCID: https://orcid.org/0000-0002-3114-7975, Zühlke, K., Geelhaar, A., Pallien, T., Hallscheidt, E., Eichhorst, J., Wiesner, B., Cernecká, H., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, von Kries, J.P.
ORCID: https://orcid.org/0000-0003-4716-4988 and Klussmann, E.
ORCID: https://orcid.org/0000-0003-4004-5003
Cells 9
(3): 673.
10 March 2020
Rapid and deep-scale ubiquitylation profiling for biology and translational research.
Udeshi, N.D.
ORCID: https://orcid.org/0000-0001-5312-1402, Mani, D.C., Satpathy, S.
ORCID: https://orcid.org/0000-0002-6040-4854, Fereshetian, S., Gasser, J.A., Svinkina, T., Olive, M.E., Ebert, B.L.
ORCID: https://orcid.org/0000-0003-0197-5451, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Carr, S.A.
ORCID: https://orcid.org/0000-0002-7203-4299
Nature Communications 11
(1): 359.
17 January 2020
Cold-induced urticarial autoinflammatory syndrome related to factor XII activation.
Scheffel, J.
ORCID: https://orcid.org/0000-0002-9365-3785, Mahnke, N.A., Hofman, Z.L.M., Maat, S.d., Wu, J., Bonnekoh, H., Pengelly, R.J.
ORCID: https://orcid.org/0000-0001-7022-645X, Ennis, S.
ORCID: https://orcid.org/0000-0003-2648-0869, Holloway, J.W.
ORCID: https://orcid.org/0000-0001-9998-0464, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Church, M.K., Maurer, M.
ORCID: https://orcid.org/0000-0002-4121-481X, Maas, C.
ORCID: https://orcid.org/0000-0003-4593-0976 and Krause, K.
ORCID: https://orcid.org/0000-0001-9711-9654
Nature Communications 11
(1): 179.
10 January 2020
Phosphorylation of RAB7 by TBK1/IKKε regulates innate immune signaling in triple negative breast cancer.
Ritter, J.L., Zhu, Z., Thai, T.C., Mahadevan, N.R., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Knelson, E.H., Piel, B.P., Han, S., Jaffe, J.D., Carr, S.A., Barbie, D.A. and Barbie, T.U.
Cancer Research 80
(1): 44-56.
January 2020
2019
Combined analysis of metabolomes, proteomes, and transcriptomes of hepatitis C virus-infected cells and liver to identify pathways associated with disease development.
Lupberger, J., Croonenborghs, T., Roca Suarez, A.A., Van Renne, N., Jühling, F., Oudot, M.A., Virzì, A., Bandiera, S., Jamey, C., Meszaros, G., Brumaru, D., Mukherji, A., Durand, S.C., Heydmann, L., Verrier, E.R., El Saghire, H., Hamdane, N., Bartenschlager, R., Fereshetian, S., Ramberger, E.
ORCID: https://orcid.org/0000-0003-2760-2696, Sinha, R., Nabian, M., Everaert, C., Jovanovic, M., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Carr, S.A., Chayama, K., Dali-Youcef, N., Ricci, R., Bardeesy, N.M., Fujiwara, N., Gevaert, O., Zeisel, M.B., Hoshida, Y., Pochet, N. and Baumert, T.F.
Gastroenterology 157
(2): 537-551.
August 2019
TMT labeling for the masses: a robust and cost-efficient, in-solution labeling approach.
Zecha, J.
ORCID: https://orcid.org/0000-0002-8767-6294, Satpathy, S., Kanashova, T., Avanessian, S.C., Kane, M.H., Clauser, K.R., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Carr, S.A. and Kuster, B.
Molecular & Cellular Proteomics 18
(7): 1468-1478.
1 July 2019
The translational landscape of the human heart.
van Heesch, S.
ORCID: https://orcid.org/0000-0001-9593-1980, Witte, F., Schneider-Lunitz, V.
ORCID: https://orcid.org/0000-0002-3980-3789, Schulz, J.F.
ORCID: https://orcid.org/0000-0002-8157-2224, Adami, E.
ORCID: https://orcid.org/0000-0002-1813-6681, Faber, A.
ORCID: https://orcid.org/0000-0003-0178-7653, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Maatz, H.
ORCID: https://orcid.org/0000-0002-9232-6272, Blachut, S.
ORCID: https://orcid.org/0009-0007-0102-9867, Sandmann, C.L.
ORCID: https://orcid.org/0000-0002-3847-0708, Kanda, M.
ORCID: https://orcid.org/0000-0003-3468-3586, Worth, C.L.
ORCID: https://orcid.org/0000-0002-1796-9606, Schafer, S., Calviello, L.
ORCID: https://orcid.org/0000-0002-5600-0988, Merriott, R., Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Wyler, E.
ORCID: https://orcid.org/0000-0002-9884-1806, Obermayer, B.
ORCID: https://orcid.org/0000-0002-9116-630X, Mücke, M.
ORCID: https://orcid.org/0000-0002-4957-3307, Lindberg, E.L.
ORCID: https://orcid.org/0000-0002-2979-433X, Trnka, F., Memczak, S.
ORCID: https://orcid.org/0000-0001-9518-7135, Schilling, M.
ORCID: https://orcid.org/0000-0002-3453-7792, Felkin, L.E., Barton, P.J.R., Quaife, N.M., Vanezis, K., Diecke, S.
ORCID: https://orcid.org/0000-0002-5219-5992, Mukai, M., Mah, N.
ORCID: https://orcid.org/0000-0002-1240-8076, Oh, S.J., Kurtz, A., Schramm, C., Schwinge, D., Sebode, M., Harakalova, M., Asselbergs, F.W., Vink, A., de Weger, R.A., Viswanathan, S., Widjaja, A.A., Gärtner-Rommel, A., Milting, H., Dos Remedios, C., Knosalla, C., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Landthaler, M.
ORCID: https://orcid.org/0000-0002-1075-8734, Vingron, M., Linke, W.A., Seidman, J.G., Seidman, C.E., Rajewsky, N.
ORCID: https://orcid.org/0000-0002-4785-4332, Ohler, U.
ORCID: https://orcid.org/0000-0002-0881-3116, Cook, S.A. and Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Cell 178
(1): 242-260.
27 June 2019
Proteogenomic analysis of human colon cancer reveals new therapeutic opportunities.
Vasaikar, S., Huang, C., Wang, X., Petyuk, V.A., Savage, S.R., Wen, B., Dou, Y., Zhang, Y., Shi, Z., Arshad, O.A., Gritsenko, M.A., Zimmerman, L.J., McDermott, J.E., Clauss, T.R., Moore, R.J., Zhao, R., Monroe, M.E., Wang, Y.T., Chambers, M.C., Slebos, R.J.C., Lau, K.S., Mo, Q., Ding, L., Ellis, M., Thiagarajan, M., Kinsinger, C.R., Rodriguez, H., Smith, R.D., Rodland, K.D., Liebler, D.C., Liu, T. and Zhang, B.
Cell 177
(4): 1035-1049.
2 May 2019
PRISMA: Protein Interaction Screen on Peptide Matrix reveals interaction footprints and modifications- dependent interactome of intrinsically disordered C/EBPb.
Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Perez Hernandez, D.
ORCID: https://orcid.org/0000-0003-0266-9050, Kowenz-Leutz, E., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Kahlert, G., Wesolowski, R.
ORCID: https://orcid.org/0009-0002-7228-1051, Baum, K.
ORCID: https://orcid.org/0000-0001-7256-0566, Knoblich, M., Hofstätter, M.
ORCID: https://orcid.org/0000-0002-6198-2859, Muller, A., Wolf, J.
ORCID: https://orcid.org/0000-0003-3254-5868, Reimer, U. and Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X
iScience 13
: 351-370.
29 March 2019
SorCS2 controls functional expression of amino acid transporter EAAT3 and protects neurons from oxidative stress and epilepsy-induced pathology.
Malik, A.R.
ORCID: https://orcid.org/0000-0001-7732-0756, Szydlowska, K., Nizinska, K., Asaro, A.
ORCID: https://orcid.org/0000-0001-9610-5381, van Vliet, E.A., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Fritsche-Guenther, R.
ORCID: https://orcid.org/0000-0002-6965-0226, Kirwan, J.A.
ORCID: https://orcid.org/0000-0002-5423-1651, Nykjaer, A., Lukasiuk, K., Aronica, E. and Willnow, T.E.
ORCID: https://orcid.org/0000-0001-9515-7921
Cell Reports 26
(10): 2792-2804.
5 March 2019
A curated resource for phosphosite-specific signature analysis.
Krug, K., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Zhang, B., Hornbeck, P., Raju, R., Ahmad, R., Szucs, M., Mundt, F., Forestier, D., Jane-Valbuena, J., Keshishian, H., Gillette, M.A., Tamayo, P., Mesirov, J.P., Jaffe, J.D.
ORCID: https://orcid.org/0000-0001-9845-1210, Carr, S.A. and Mani, D.R.
Molecular & Cellular Proteomics 18
(3): 576-593.
1 March 2019
Collagen I-based scaffolds negatively impact fracture healing in a mouse-osteotomy-model although used routinely in research and clinical application.
Lang, A., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Stefanowski, J., Durst, M., Weber, M.C., Pfeiffenberger, M., Damerau, A., Hauser, A.E., Hoff, P., Duda, G.N., Buttgereit, F., Schmidt-Bleek, K. and Gaber, T.
Acta Biomaterialia 86
: 171-184.
1 March 2019
Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress.
Jochner, M.C.E., An, J., Lättig-Tünnemann, G.
ORCID: https://orcid.org/0000-0001-6485-1136, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Dagane, A., Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Dirnagl, U., Eickholt, B.J. and Harms, C.
ORCID: https://orcid.org/0000-0002-2063-2860
Scientific Reports 9
(1): 3183.
28 February 2019
Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma.
Haage, V.
ORCID: https://orcid.org/0000-0001-7569-8421, Semtner, M.
ORCID: https://orcid.org/0000-0001-9379-9023, Oliveira Vidal, R.
ORCID: https://orcid.org/0000-0003-4217-2014, Perez Hernandez, D.
ORCID: https://orcid.org/0000-0003-0266-9050, Pong, W.W., Chen, Z., Hambardzumyan, D., Magrini, V., Ly, A., Walker, J., Mardis, E., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Sauer, S.
ORCID: https://orcid.org/0000-0002-4794-3693, Kettenmann, H.
ORCID: https://orcid.org/0000-0001-8208-0291 and Gutmann, D.H.
ORCID: https://orcid.org/0000-0002-3127-5045
Acta Neuropathologica Communications 7
(1): 20.
14 February 2019
Small and large ribosomal subunit deficiencies lead to distinct gene expression signatures that reflect cellular growth rate.
Cheng, Z., Mugler, C.F., Keskin, A., Hodapp, S., Chan, L.Y.L., Weis, K., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Regev, A., Jovanovic, M. and Brar, G.A.
Molecular Cell 73
(1): 36-47.
3 January 2019
MRG-1/MRG15 is a barrier for germ cell to neuron reprogramming in Caenorhabditis elegans.
Hajduskova, M., Baytek, G.
ORCID: https://orcid.org/0000-0001-9731-9461, Kolundzic, E.
ORCID: https://orcid.org/0000-0002-7811-3174, Gosdschan, A.
ORCID: https://orcid.org/0000-0003-3045-8234, Kazmierczak, M., Ofenbauer, A.
ORCID: https://orcid.org/0000-0003-0379-9105, Beato del Rosal, M.L., Herzog, S., ul Fatima, N.
ORCID: https://orcid.org/0000-0002-5934-7215, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Seelk-Müthel, S.
ORCID: https://orcid.org/0000-0002-3525-8859 and Tursun, B.
ORCID: https://orcid.org/0000-0001-7293-8629
Genetics 211
(1): 121-139.
1 January 2019
2018
The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N., Kolesnichenko, M.
ORCID: https://orcid.org/0000-0001-7366-9061, Beaudette, P., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Uyar, B.
ORCID: https://orcid.org/0000-0002-3170-4890, Sun, W.
ORCID: https://orcid.org/0000-0001-9607-1361, Tufan, A.B.
ORCID: https://orcid.org/0000-0002-8734-9736, Perder, B., Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117, Chen, W.
ORCID: https://orcid.org/0000-0003-3263-1627, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Hinz, M.
ORCID: https://orcid.org/0000-0003-2611-4121 and Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129
EMBO Journal 37
(24): e98658.
14 December 2018
On the relation between filament density, force generation and protrusion rate in mesenchymal cell motility.
Dolati, S., Kage, F., Mueller, J., Müsken, M., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Dittmar, G., Sixt, M., Rottner, K. and Falcke, M.
ORCID: https://orcid.org/0000-0001-7137-1114
Molecular Biology of the Cell 29
(22): 2674-2686.
1 November 2018
PPM1D truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells.
Kahn, J.D., Miller, P.G., Silver, A.J., Sellar, R.S., Bhatt, S., Gibson, C., McConkey, M., Adams, D., Mar, B., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Fereshetian, S., Krug, K., Zhu, H., Letai, A., Carr, S.A., Doench, J., Jaiswal, S. and Ebert, B.L.
Blood 132
(11): 1095-1105.
13 September 2018
Proteomics, post-translational modifications, and integrative analyses reveal molecular heterogeneity within medulloblastoma subgroups.
Archer, T.C., Ehrenberger, T., Mundt, F., Gold, M.P., Krug, K., Mah, C.K., Mahoney, E.L., Daniel, C.J., LeNail, A., Ramamoorthy, D., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Mani, D.R., Zhang, H., Gillette, M.A., Clauser, K., Noble, M., Tang, L.C., Pierre-François, J., Silterra, J., Jensen, J., Tamayo, P., Korshunov, A., Pfister, S.M., Kool, M., Northcott, P.A., Sears, R.C., Lipton, J.O., Carr, S.A., Mesirov, J.P., Pomeroy, S.L. and Fraenkel, E.
Cancer Cell 34
(3): 396-410.
10 September 2018
Transcriptional and translational differences of microglia from male and female brains.
Guneykaya, D.
ORCID: https://orcid.org/0000-0001-5723-0737, Ivanov, A.
ORCID: https://orcid.org/0000-0002-4824-1925, Perez Hernandez, D.
ORCID: https://orcid.org/0000-0003-0266-9050, Haage, V.
ORCID: https://orcid.org/0000-0001-7569-8421, Wojtas, B., Meyer, N.
ORCID: https://orcid.org/0000-0002-8377-097X, Maricos, M.
ORCID: https://orcid.org/0000-0002-3873-6887, Jordan, P., Buonfiglioli, A.
ORCID: https://orcid.org/0000-0002-5550-9360, Gielniewski, B., Ochocka, N., Cömert, C., Friedrich, C.
ORCID: https://orcid.org/0000-0002-5586-1989, Suarez Artiles, L.
ORCID: https://orcid.org/0000-0001-7991-5446, Kaminska, B., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632, Kettenmann, H.
ORCID: https://orcid.org/0000-0001-8208-0291 and Wolf, S.A.
ORCID: https://orcid.org/0000-0003-0922-8418
Cell Reports 24
(10): 2773-2783.
4 September 2018
Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry.
Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Tang, L.C.
ORCID: https://orcid.org/0000-0001-8786-5418, Krug, K., Clark, D.J., Gritsenko, M.A., Chen, L., Clauser, K.R., Clauss, T.R., Shah, P., Gillette, M.A., Petyuk, V.A., Thomas, S.N.
ORCID: https://orcid.org/0000-0003-1679-5453, Mani, D.R., Mundt, F., Moore, R.J., Hu, Y., Zhao, R., Schnaubelt, M., Keshishian, H., Monroe, M.E., Zhang, Z., Udeshi, N.D.
ORCID: https://orcid.org/0000-0001-5312-1402, Mani, D., Davies, S.R., Townsend, R.R., Chan, D.W., Smith, R.D., Zhang, H., Liu, T.
ORCID: https://orcid.org/0000-0001-9529-6550 and Carr, S.A.
ORCID: https://orcid.org/0000-0002-7203-4299
Nature Protocols 13
(7): 1632-1661.
July 2018
Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.
Wong, G.S., Zhou, J., Liu, J.B., Wu, Z., Xu, X., Li, T., Xu, D., Schumacher, S.E., Puschhof, J., McFarland, J., Zou, C., Dulak, A., Henderson, L., Xu, P., O'Day, E., Rendak, R., Liao, W.L., Cecchi, F., Hembrough, T., Schwartz, S., Szeto, C., Rustgi, A.K., Wong, K.K., Diehl, J.A.
ORCID: https://orcid.org/0000-0001-9854-5049, Jensen, K., Graziano, F., Ruzzo, A., Fereshetian, S., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Carr, S.A.
ORCID: https://orcid.org/0000-0002-7203-4299, Beroukhim, R., Nakamura, K., Oki, E., Watanabe, M., Baba, H., Imamura, Y., Catenacci, D. and Bass, A.J.
Nature Medicine 24
(7): 968-977.
July 2018
Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple-negative breast cancers.
Mundt, F., Rajput, S., Li, S., Ruggles, K.V., Mooradian, A.D., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Gillette, M.A., Krug, K., Guo, Z., Hoog, J., Erdmann-Gilmore, P., Primeau, T., Huang, S., Edwards, D.P., Wang, X., Wang, X., Kawaler, E., Mani, D.R., Clauser, K.R., Gao, F., Luo, J., Davies, S.R., Johnson, G.L., Huang, K.L., Yoon, C.J., Ding, L., Fenyö, D., Ellis, M.J., Townsend, R.R., Held, J.M., Carr, S.A. and Ma, C.X.
Cancer Research 78
(10): 2732-2746.
May 2018
CLCN2 chloride channel mutations in familial hyperaldosteronism type II.
Scholl, U.I.
ORCID: https://orcid.org/0000-0002-0309-8045, Stölting, G.
ORCID: https://orcid.org/0000-0002-2339-0545, Schewe, J., Thiel, A.
ORCID: https://orcid.org/0000-0002-9523-2351, Tan, H., Nelson-Williams, C.
ORCID: https://orcid.org/0000-0003-0768-4751, Vichot, A.A., Jin, S.C., Loring, E., Untiet, V.
ORCID: https://orcid.org/0000-0002-1888-6378, Yoo, T., Choi, J., Xu, S., Wu, A., Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Rump, L.C., Onder, A.M., Gamble, C., McKenney, D., Lash, R.W., Jones, D.P., Chune, G., Gagliardi, P., Choi, M.
ORCID: https://orcid.org/0000-0002-9195-1455, Gordon, R., Stowasser, M., Fahlke, C. and Lifton, R.P.
Nature Genetics 50
(3): 349-354.
March 2018
Picky: a simple online PRM and SRM method designer for targeted proteomics.
Zauber, H.
ORCID: https://orcid.org/0000-0003-2595-1147, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X and Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751
Nature Methods 15
(3): 156-157.
28 February 2018
Pervasive, coordinated protein-level changes driven by transcript isoform switching during meiosis.
Cheng, Z., Otto, G.M., Powers, E.N., Keskin, A., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Carr, S.A., Jovanovic, M. and Brar, G.A.
Cell 172
(5): 910-923.
22 February 2018
Adaptive and reversible resistance to Kras inhibition in pancreatic cancer cells.
Chen, P.Y., Muzumdar, M.D., Dorans, K.J., Robbins, R.A., Bhutkar, A., Del Rosario, A.M., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Qiao, J., Schaefer, C., Gertler, F.B., Carr, S.A. and Jacks, T.
Cancer Research 78
(4): 985-1002.
15 February 2018
2017
Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1.
Tripathi, B.K., Grant, T.
ORCID: https://orcid.org/0000-0003-4243-1637, Qian, X., Zhou, M., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Wang, D., Papageorge, A.G., Tarasov, S.G.
ORCID: https://orcid.org/0000-0002-7134-0374, Hunter, K.W.
ORCID: https://orcid.org/0000-0001-5963-8808, Carr, S.A. and Lowy, D.R.
ORCID: https://orcid.org/0000-0003-0635-219X
Journal of Cell Biology 216
(12): 4255.
4 December 2017
An integrative framework reveals signaling-to-transcription events in toll-like receptor signaling.
Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Przybylski, D., Yosef, N., Qiao, J., Clauser, K., Raychowdhury, R., Eisenhaure, T.M., Maritzen, T., Haucke, V., Satoh, T., Akira, S., Carr, S.A., Regev, A., Hacohen, N. and Chevrier, N.
Cell Reports 19
(13): 2853-2866.
27 June 2017
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.
Tobe, B.T.D., Crain, A.M., Winquist, A.M., Calabrese, B., Makihara, H., Zhao, W.N., Lalonde, J., Nakamura, H., Konopaske, G., Sidor, M., Pernia, C.D., Yamashita, N., Wada, M., Inoue, Y., Nakamura, F., Sheridan, S.D., Logan, R.W., Brandel, M., Wu, D., Hunsberger, J., Dorsett, L., Duerr, C., Basa, R.C.B., McCarthy, M.J., Udeshi, N.D., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Carr, S.A., Rouleau, G.A., Mastrangelo, L., Li, J., Gutierrez, G.J., Brill, L.M., Venizelos, N., Chen, G., Nye, J.S., Manji, H., Price, J.H., McClung, C.A., Akiskal, H.S., Alda, M., Chuang, D.M.M., Coyle, J.T., Liu, Y., Teng, Y.D., Ohshima, T., Mikoshiba, K., Sidman, R.L., Halpain, S., Haggarty, S.J., Goshima, Y. and Snyder, E.Y.
Proceedings of the National Academy of Sciences of the United States of America 114
(22): E4462-E4471.
30 May 2017
Proteogenomic integration reveals therapeutic targets in breast cancer xenografts.
Huang, K.L., Li, S., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Cao, S., Gunawardena, H.P., Ruggles, K.V., Mani, D.R., Clauser, K.R., Tanioka, M., Usary, J., Kavuri, S.M., Xie, L., Yoon, C., Qiao, J.W., Wrobel, J., Wyczalkowski, M.A., Erdmann-Gilmore, P., Snider, J.E., Hoog, J., Singh, P., Niu, B., Guo, Z., Sun, S.Q., Sanati, S., Kawaler, E., Wang, X., Scott, A., Ye, K., McLellan, M.D., Wendl, M.C., Malovannaya, A., Held, J.M., Gillette, M.A., Fenyö, D., Kinsinger, C.R., Mesri, M., Rodriguez, H., Davies, S.R., Perou, C.M., Ma, C., Townsend, R.R., Chen, X., Carr, S.A., Ellis, M.J. and Ding, L.
Nature Communications 8
: 14864.
28 March 2017
Proteome profiling outperforms transcriptome profiling for coexpression based gene function prediction.
Wang, J., Ma, Z., Carr, S.A., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Zhang, H., Zhang, Z., Chan, D.W., Ellis, M.J.C., Townsend, R.R., Smith, R.D., McDermott, J.E., Chen, X., Paulovich, A.G., Boja, E.S., Mesri, M., Kinsinger, C.R., Rodriguez, H., Rodland, K.D., Liebler, D.C. and Zhang, B.
Molecular & Cellular Proteomics 16
(1): 121-134.
1 January 2017
2016
Integrated proteogenomic characterization of human high-grade serous ovarian cancer.
Zhang, H., Liu, T., Zhang, Z., Payne, S.H., Zhang, B., McDermott, J.E., Zhou, J.Y., Petyuk, V.A., Chen, L., Ray, D., Sun, S., Yang, F., Chen, L., Wang, J., Shah, P., Cha, S.W., Aiyetan, P., Woo, S., Tian, Y., Gritsenko, M.A., Clauss, T.R., Choi, C., Monroe, M.E., Thomas, S., Nie, S., Wu, C., Moore, R.J., Yu, K.H., Tabb, D.L., Fenyö, D., Bafna, V., Wang, Y., Rodriguez, H., Boja, E.S., Hiltke, T., Rivers, R.C., Sokoll, L., Zhu, H., Shih, I.M., Cope, L., Pandey, A., Zhang, B., Snyder, M.P., Levine, D.A., Smith, R.D., Chan, D.W. and Rodland, K.D.
Cell 166
(3): 755-765.
28 July 2016
Proteogenomics connects somatic mutations to signalling in breast cancer.
Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Mani, D.R., Ruggles, K.V., Gillette, M.A., Clauser, K.R., Wang, P., Wang, X., Qiao, J.W., Cao, S., Petralia, F., Kawaler, E., Mundt, F., Krug, K., Tu, Z., Lei, J.T., Gatza, M.L., Wilkerson, M., Perou, C.M., Yellapantula, V., Huang, K.L., Lin, C., McLellan, M.D., Yan, P., Davies, S.R., Townsend, R.R., Skates, S.J., Wang, J., Zhang, B., Kinsinger, C.R., Mesri, M., Rodriguez, H., Ding, L., Paulovich, A.G., Fenyoe, D., Ellis, M.J. and Carr, S.A.
Nature 534
(7605): 55-62.
2 June 2016
Reproducibility of differential proteomic technologies in CPTAC fractionated xenografts.
Tabb, D.L., Wang, X., Carr, S.A., Clauser, K.R., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Chambers, M.C., Holman, J.D., Wang, J., Zhang, B., Zimmerman, L.J., Chen, X., Gunawardena, H.P., Davies, S.R., Ellis, M.J.C., Li, S., Townsend, R.R., Boja, E.S., Ketchum, K.A., Kinsinger, C.R., Mesri, M., Rodriguez, H., Liu, T., Kim, S., McDermott, J.E., Payne, S.H., Petyuk, V.A., Rodland, K.D., Smith, R.D., Yang, F., Chan, D.W., Zhang, B., Zhang, H., Zhang, Z., Zhou, J.Y. and Liebler, D.C.
Journal of Proteome Research 15
(3): 691-706.
4 March 2016
An analysis of the sensitivity of proteogenomic mapping of somatic mutations and novel splicing events in cancer.
Ruggles, K.V., Tang, Z., Wang, X., Grover, H., Askenazi, M., Teubl, J., Cao, S., McLellan, M.D., Clauser, K.R., Tabb, D.L., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Slebos, R., Erdmann-Gilmore, P., Li, S., Gunawardena, H.P., Xie, L., Liu, T., Zhou, J.Y., Sun, S., Hoadley, K.A., Perou, C.M., Chen, X., Davies, S.R., Maher, C.A., Kinsinger, C.R., Rodland, K.D., Zhang, H., Zhang, Z., Ding, L., Townsend, R.R., Rodriguez, H., Chan, D., Smith, R.D., Liebler, D.C., Carr, S.A., Payne, S., Ellis, M.J. and Fenyö, D.
Molecular & Cellular Proteomics 15
(3): 1060-1071.
1 March 2016
2015
A regression-based analysis of ribosome-profiling data reveals a conserved complexity to mammalian translation.
Fields, A.P., Rodriguez, E.H., Jovanovic, M., Stern-Ginossar, N., Haas, B.J., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Raychowdhury, R., Hacohen, N., Carr, S.A., Ingolia, N.T., Regev, A. and Weissman, J.S.
Molecular Cell 60
(5): 816-827.
3 December 2015
Deep, quantitative coverage of the lysine acetylome using novel anti-acetyl-lysine antibodies and an optimized proteomic workflow.
Svinkina, T., Gu, H., Silva, J.C., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Qiao, J., Fereshetian, S., Jaffe, J.D., Kuhn, E., Udeshi, N.D. and Carr, S.A.
Molecular & Cellular Proteomics 14
(9): 2429-2440.
1 September 2015
Multiplexed, quantitative workflow for sensitive biomarker discovery in plasma yields novel candidates for early myocardial injury.
Keshishian, H., Burgess, M.W., Gillette, M.A., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Clauser, K.R., Mani, D.R., Kuhn, E.W., Farrell, L.A., Gerszten, R.E. and Carr, S.A.
Molecular & Cellular Proteomics 14
(9): 2375-2393.
1 September 2015
A Genome-wide CRISPR screen in primary immune cells to dissect regulatory networks.
Parnas, O., Jovanovic, M., Eisenhaure, T.M., Herbst, R.H., Dixit, A., Ye, C.J., Przybylski, D., Platt, R.J., Tirosh, I., Sanjana, N.E., Shalem, O., Satija, R., Raychowdhury, R., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Carr, S.A., Zhang, F., Hacohen, N. and Regev, A.
Cell 162
(3): 675-686.
30 July 2015
Functional proteomic analysis of repressive histone methyltransferase complexes reveals ZNF518B as a G9A regulator.
Maier, V.K., Feeney, C.M., Taylor, J.E., Creech, A.L., Qiao, J.W., Szanto, A., Das, P.P., Chevrier, N., Cifuentes-Rojas, C., Orkin, S.H., Carr, S.A., Jaffe, J.D., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Lee, J.T.
Molecular & Cellular Proteomics 14
(6): 1435-1446.
1 June 2015
Dynamic profiling of the protein life cycle in response to pathogens.
Jovanovic, M., Rooney, M.S., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Przybylski, D., Chevrier, N., Satija, R., Rodriguez, E.H., Fields, A.P., Schwartz, S., Raychowdhury, R., Mumbach, M.R., Eisenhaure, T., Rabani, M., Gennert, D., Lu, D., Delorey, T., Weissman, J.S., Carr, S.A., Hacohen, N. and Regev, A.
Science 347
(6226): 1259038.
6 March 2015
2014
CDK5 is a major regulator of the tumor suppressor DLC1.
Tripathi, B.K., Qian, X., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Wang, D., Papageorge, A.G., Carr, S.A. and Lowy, D.R.
Journal of Cell Biology 207
(5): 627-642.
8 December 2014
Proteogenomic characterization of human colon and rectal cancer.
Zhang, B., Wang, J., Wang, X., Zhu, J., Liu, Q., Shi, Z., Chambers, M.C., Zimmerman, L.J., Shaddox, K.F., Kim, S., Davies, S.R., Wang, S., Wang, P., Kinsinger, C.R., Rivers, R.C., Rodriguez, H., Townsend, R.R., Ellis, M.J.C., Carr, S.A., Tabb, D.L., Coffey, R.J., Slebos, R.J.C. and Liebler, D.C.
Nature 513
(7518): 382-387.
18 September 2014
Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites.
Schwartz, S., Mumbach, M.R., Jovanovic, M., Wang, T., Maciag, K., Bushkin, G.G., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Ter-Ovanesyan, D., Habib, N., Cacchiarelli, D., Sanjana, N.E., Freinkman, E., Pacold, M.E., Satija, R., Mikkelsen, T.S., Hacohen, N., Zhang, F., Carr, S.A., Lander, E.S. and Regev, A.
Cell Reports 8
(1): 284-296.
10 July 2014
Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.
Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Yang, F., Liu, T., Mani, D.R., Petyuk, V.A., Gillette, M.A., Clauser, K.R., Qiao, J.W., Gritsenko, M.A., Moore, R.J., Levine, D.A., Townsend, R., Erdmann-Gilmore, P., Snider, J.E., Davies, S.R., Ruggles, K.V., Fenyo, D., Kitchens, R.T., Li, S., Olvera, N., Dao, F., Rodriguez, H., Chan, D.W., Liebler, D., White, F., Rodland, K.D., Mills, G.B., Smith, R.D., Paulovich, A.G., Ellis, M. and Carr, S.A.
Molecular & Cellular Proteomics 13
(7): 1690-1704.
1 July 2014
Quantitative-proteomic comparison of alpha and beta cells to uncover novel targets for lineage reprogramming.
Choudhary, A., He, K.H., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Udeshi, N.D., Dančík, V., Fomina-Yadlin, D., Kubicek, S., Clemons, P.A., Schreiber, S.L., Carr, S.A. and Wagner, B.K.
PLoS ONE 9
(4): e95194.
23 April 2014
2013
High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis.
Schwartz, S., Agarwala, S.D., Mumbach, M.R., Jovanovic, M., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Shishkin, A., Tabach, Y., Mikkelsen, T.S., Satija, R., Ruvkun, G., Carr, S.A., Lander, E.S., Fink, G.R. and Regev, A.
Cell 155
(6): 1409-1421.
5 December 2013
Large-scale identification of ubiquitination sites by mass spectrometry.
Udeshi, N.D., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Svinkina, T. and Carr, S.A.
Nature Protocols 8
(10): 1950-1960.
October 2013
Integrated proteomic analysis of post-translational modifications by serial enrichment.
Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Qiao, J.W., Patel, J., Udeshi, N.D., Clauser, K.R., Mani, D.R., Burgess, M.W., Gillette, M.A., Jaffe, J.D. and Carr, S.A.
Nature Methods 10
(7): 634-637.
July 2013
Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activator.
Vlaicu, P., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Mayr, T., Widschwendter, P., Ataseven, B., Högel, B., Eiermann, W., Knyazev, P. and Ullrich, A.
BMC Cancer 13
: 197.
18 April 2013
Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
Udeshi, N.D., Svinkina, T., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Kuhn, E., Mani, D.R., Qiao, J.W. and Carr, S.A.
Molecular & Cellular Proteomics 12
(3): 825-831.
1 March 2013
Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.
Lee, M.N., Roy, M., Ong, S.E., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Villani, A.C., Li, W., Dotiwala, F., Sen, J., Doench, J.G., Orzalli, M.H., Kramnik, I., Knipe, D.M., Lieberman, J., Carr, S.A. and Hacohen, N.
Nature Immunology 14
(2): 179-185.
February 2013
2012
Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.
Greulich, H., Kaplan, B., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Chen, T.H., Tanaka, K.E., Yun, C.H., Zhang, X., Lee, S.H., Cho, J., Ambrogio, L., Liao, R., Imielinski, M., Banerji, S., Berger, A.H., Lawrence, M.S., Zhang, J., Pho, N.H., Walker, S.R., Winckler, W., Getz, G., Frank, D., Hahn, W.C., Eck, M.J., Mani, D.R., Jaffe, J.D., Carr, S.A., Wong, K.K. and Meyerson, M.
Proceedings of the National Academy of Sciences of the United States of America 109
(36): 14476-14481.
4 September 2012
iTRAQ labeling is superior to mTRAQ for quantitative global proteomics and phosphoproteomics.
Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Udeshi, N.D., Clauser, K.R., Mani, D.R., Patel, J., Ong, S.E., Jaffe, J.D. and Carr, S.A.
Molecular & Cellular Proteomics 11
(6): M111.014423.
1 June 2012
Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
Udeshi, N.D., Mani, D.R., Eisenhaure, T., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Jaffe, J.D., Clauser, K.R., Hacohen, N. and Carr, S.A.
Molecular & Cellular Proteomics 11
(5): 148-159.
1 May 2012
2011
Systematic discovery of TLR signaling components delineates viral-sensing circuits.
Chevrier, N., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Artyomov, M.N., Shalek, A.K., Iannacone, M., Ciaccio, M.F., Gat-Viks, I., Tonti, E., DeGrace, M.M., Clauser, K.R., Garber, M., Eisenhaure, T.M., Yosef, N., Robinson, J., Sutton, A., Andersen, M.S., Root, D.E., von Andrian, U., Jones, R.B., Park, H., Carr, S.A., Regev, A., Amit, I. and Hacohen, N.
Cell 147
(4): 853-867.
10 November 2011
2008
Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.
Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Eberl, H.C., Renkawitz, J., Olsen, J.V., Tremblay, M.L., Mann, M., Ullrich, A. and Daub, H.
Molecular & Cellular Proteomics 7
(9): 1763-1777.
September 2008
2006
Furin-, ADAM 10-, and γ-secretase-mediated cleavage of a receptor tyrosine phosphatase and regulation of β-catenin's transcriptional activity.
Anders, L., Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Lammich, S., Murgia, M., Hartmann, D., Saftig, P., Haass, C. and Ullrich, A.
Molecular and Cellular Biology 26
(10): 3917-3934.
May 2006
This list was generated on Mon Jun 22 22:37:20 2026 UTC.