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BMC Cancer

CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing.
Andersch, L. and Radke, J. and Klaus, A. and Schwiebert, S. and Winkler, A. and Schumann, E. and Grunewald, L. and Zirngibl, F. and Flemmig, C. and Jensen, M.C. and Rossig, C. and Joussen, A. and Henssen, A. and Eggert, A. and Schulte, J.H. and Künkele, A.
BMC Cancer 19 (1): 895. 9 September 2019

BMC Genomics

Forward genetic screen of human transposase genomic rearrangements.
Henssen, A.G. and Jiang, E. and Zhuang, J. and Pinello, L. and Socci, N.D. and Koche, R. and Gonen, M. and Villasante, C.M. and Armstrong, S.A. and Bauer, D.E. and Weng, Z. and Kentsis, A.
BMC Genomics 17 : 548. 4 August 2016

Cancer Letters

Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.
Han, Y. and Lindner, S. and Bei, Y. and Garcia, H.D. and Timme, N. and Althoff, K. and Odersky, A. and Schramm, A. and Lissat, A. and Künkele, A. and Deubzer, H.E. and Eggert, A. and Schulte, J.H. and Henssen, A.G.
Cancer Letters 445 : 24-33. 31 March 2019

Cancers

High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive Ewing sarcoma.
Orth, M.F. and Hölting, T.L.B. and Dallmayer, M. and Wehweck, F.S. and Paul, T. and Musa, J. and Baldauf, M.C. and Surdez, D. and Delattre, O. and Knott, M.M.L. and Romero-Pérez, L. and Kasan, M. and Cidre-Aranaz, F. and Gerke, J.S. and Ohmura, S. and Li, J. and Marchetto, A. and Henssen, A.G. and Özen, Ö. and Sugita, S. and Hasegawa, T. and Kanaseki, T. and Bertram, S. and Dirksen, U. and Hartmann, W. and Kirchner, T. and Grünewald, T.G.P.
Cancers 12 (3): 644. 10 March 2020

Clinical Cancer Research

Targeting MYCN-driven transcription by BET-bromodomain inhibition.
Henssen, A. and Althoff, K. and Odersky, A. and Beckers, A. and Koche, R. and Speleman, F. and Schäfers, S. and Bell, E. and Nortmeyer, M. and Westermann, F. and De Preter, K. and Florin, A. and Heukamp, L. and Spruessel, A. and Astrahanseff, K. and Lindner, S. and Sadowski, N. and Schramm, A. and Astorgues-Xerri, L. and Riveiro, M.E. and Eggert, A. and Cvitkovic, E. and Schulte, J.H.
Clinical Cancer Research 22 (10): 2470-2481. May 2016

Clinical Chemistry

What is extrachromosomal circular DNA and what does it do?
Chiu, R.W.K. and Dutta, A. and Hensson, A.G. and Lo, Y.M.D. and Mischel, P. and Regenberg, B.
Clinical Chemistry 66 (6): 754-759. June 2020

Cortex

Cytoarchitecture and probability maps of the human medial orbitofrontal cortex.
Henssen, A. and Zilles, K. and Palomero-Gallagher, N. and Schleicher, A. and Mohlberg, H. and Gerboga, F. and Eickhoff, S.B. and Bludau, S. and Amunts, K.
Cortex 75 : 87-112. February 2016

Frontiers in Immunology

Tumor-derived extracellular vesicles impair CD171-specific CD4(+) CAR T cell efficacy.
Ali, S. and Toews, K. and Schwiebert, S. and Klaus, A. and Winkler, A. and Grunewald, L. and Oevermann, L. and Deubzer, H.E. and Tüns, A. and Jensen, M.C. and Henssen, A.G. and Eggert, A. and Schulte, J.H. and Schwich, E. and Rebmann, V. and Schramm, A. and Künkele, A.
Frontiers in Immunology 11 : 531. 31 March 2020

Frontiers in Oncology

Current and future treatment strategies for rhabdomyosarcoma.
Chen, C. and Dorado Garcia, H. and Scheer, M. and Henssen, A.G.
Frontiers in Oncology 9 : 1458. 20 December 2019

International Journal of Cancer

Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model.
Thole, T.M. and Toedling, J. and Sprüssel, A. and Pfeil, S. and Savelyeva, L. and Capper, D. and Messerschmidt, C. and Beule, D. and Groeneveld-Krentz, S. and Eckert, C. and Gambara, G. and Henssen, A.G. and Finkler, S. and Schulte, J.H. and Sieber, A. and Bluethgen, N. and Regenbrecht, C.R.A. and Künkele, A. and Lodrini, M. and Eggert, A. and Deubzer, H.E.
International Journal of Cancer 146 (4): 1031-1041. 15 February 2020

JCI Insight

Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor.
Ortiz, M.V. and Ahmed, S. and Burns, M. and Henssen, A.G. and Hollmann, T.J. and MacArthur, I. and Gunasekera, S. and Gaewsky, L. and Bradwin, G. and Ryan, J. and Letai, A. and He, Y. and Naranjo, A. and Chi, Y.Y. and LaQuaglia, M. and Heaton, T. and Cifani, P. and Dome, J.S. and Gadd, S. and Perlman, E. and Mullen, E. and Steen, H. and Kentsis, A.
JCI Insight 4 (15): e127098. 8 August 2019

Prohibitin promotes dedifferentiation and is a potential therapeutic target in neuroblastoma.
MacArthur, I.C. and Bei, Y. and Garcia, H.D. and Ortiz, M.V. and Toedling, J. and Klironomos, F. and Rolff, J. and Eggert, A. and Schulte, J.H. and Kentsis, A. and Henssen, A.G.
JCI Insight 4 (10): e127130. 16 May 2019

Emerging functions of DNA transposases and oncogenic mutators in childhood cancer development.
Henssen, A.G. and Kentsis, A.
JCI Insight 3 (20): 123172. 18 October 2018

Journal of Cancer Research and Clinical Oncology

Synovial sarcoma disease characteristics and primary tumor sites differ between patient age groups: a report of the Cooperative Weichteilsarkom Studiengruppe (CWS).
Scheer, M. and Blank, B. and Bauer, S. and Vokuhl, C. and Stegmaier, S. and Feuchtgruber, S. and Henssen, A. and Sparber-Sauer, M. and Eggert, A. and Handgretinger, R. and Pekrun, A. and Rossig, C. and Rutkowski, S. and Schlegel, P.G. and Schrappe, M. and Simon, T. and Kazanowska, B. and Niggli, F. and Ladenstein, R. and Ljungman, G. and Jahnukainen, K. and Fuchs, J. and Bielack, S.S. and Koscielniak, E. and Klingebiel, T.
Journal of Cancer Research and Clinical Oncology 146 (4): 953-960. April 2020

Molecular Carcinogenesis

Central memory phenotype drives success of checkpoint inhibition in combination with CAR T cells.
Toews, K. and Grunewald, L. and Schwiebert, S. and Klaus, A. and Winkler, A. and Ali, S. and Zirngibl, F. and Astrahantseff, K. and Wagner, D.L. and Henssen, A.G. and Deubzer, H.E. and Schulte, J.H. and Ochsenreither, S. and Eggert, A. and Künkele, A.
Molecular Carcinogenesis 59 (7): 724-273. July 2020

Nature Communications

Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing.
Stangl, C. and de Blank, S. and Renkens, I. and Westera, L. and Verbeek, T. and Valle-Inclan, J.E. and González, R.C. and Henssen, A.G. and van Roosmalen, M.J. and Stam, R.W. and Voest, E.E. and Kloosterman, W.P. and van Haaften, G. and Monroe, G.R.
Nature Communications 11 (1): 2861. 5 June 2020

Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Marchetto, A. and Ohmura, S. and Orth, M.F. and Knott, M.M.L. and Colombo, M.V. and Arrigoni, C. and Bardinet, V. and Saucier, D. and Wehweck, F.S. and Li, J. and Stein, S. and Gerke, J.S. and Baldauf, M.C. and Musa, J. and Dallmayer, M. and Romero-Pérez, L. and Hölting, T.L.B. and Amatruda, J.F. and Cossarizza, A. and Henssen, A.G. and Kirchner, T. and Moretti, M. and Cidre-Aranaz, F. and Sannino, G. and Grünewald, T.G.P.
Nature Communications 11 (1): 2423. 15 May 2020

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets.
Decaesteker, B. and Denecker, G. and Van Neste, C. and Dolman, E.M. and Van Loocke, W. and Gartlgruber, M. and Nunes, C. and De Vloed, F. and Depuydt, P. and Verboom, K. and Rombaut, D. and Loontiens, S. and De Wyn, J. and Kholosy, W.M. and Koopmans, B. and Essing, A.H.W. and Herrmann, C. and Dreidax, D. and Durinck, K. and Deforce, D. and van Nieuwerburgh, F. and Henssen, A. and Versteeg, R. and Boeva, V. and Schleiermacher, G. and van Nes, J. and Mestdagh, P. and Vanhauwaert, S. and Schulte, J.H. and Westermann, F. and Molenaar, J.J. and De Preter, K. and Speleman, F.
Nature Communications 9 (1): 4866. 19 November 2018

Nature Genetics

Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Koche, R.P. and Rodriguez-Fos, E. and Helmsauer, K. and Burkert, M. and MacArthur, I.C. and Maag, J. and Chamorro, R. and Munoz-Perez, N. and Puiggròs, M. and Dorado Garcia, H. and Bei, Y. and Röefzaad, C. and Bardinet, V. and Szymansky, A. and Winkler, A. and Thole, T. and Timme, N. and Kasack, K. and Fuchs, S. and Klironomos, F. and Thiessen, N. and Blanc, E. and Schmelz, K. and Künkele, A. and Hundsdörfer, P. and Rosswog, C. and Theissen, J. and Beule, D. and Deubzer, H. and Sauer, S. and Toedling, J. and Fischer, M. and Hertwig, F. and Schwarz, R.F. and Eggert, A. and Torrents, D. and Schulte, J.H. and Henssen, A.G.
Nature Genetics 52 (1): 29-34. January 2020

PGBD5 promotes site-specific oncogenic mutations in human tumors.
Henssen, A.G. and Koche, R. and Zhuang, J. and Jiang, E. and Reed, C. and Eisenberg, A. and Still, E. and MacArthur, I.C. and Rodríguez-Fos, E. and Gonzalez, S. and Puiggròs, M. and Blackford, A.N. and Mason, C.E. and de Stanchina, E. and Gönen, M. and Emde, A.K. and Shah, M. and Arora, K. and Reeves, C. and Socci, N.D. and Perlman, E. and Antonescu, C.R. and Roberts, C.W.M. and Steen, H. and Mullen, E. and Jackson, S.P. and Torrents, D. and Weng, Z. and Armstrong, S.A. and Kentsis, A.
Nature Genetics 49 (7): 1005-1014. July 2017

Mutational dynamics between primary and relapse neuroblastomas.
Schramm, A. and Köster, J. and Assenov, Y. and Althoff, K. and Peifer, M. and Mahlow, E. and Odersky, A. and Beisser, D. and Ernst, C. and Henssen, A.G. and Stephan, H. and Schröder, C. and Heukamp, L. and Engesser, A. and Kahlert, Y. and Theissen, J. and Hero, B. and Roels, F. and Altmüller, J. and Nürnberg, P. and Astrahantseff, K. and Gloeckner, C. and De Preter, K. and Plass, C. and Lee, S. and Lode, H.N. and Henrich, K.O. and Gartlgruber, M. and Speleman, F. and Schmezer, P. and Westermann, F. and Rahmann, S. and Fischer, M. and Eggert, A. and Schulte, J.H.
Nature Genetics 47 (8): 872-877. August 2015

Oncotarget

Targeting tachykinin receptors in neuroblastoma.
Henssen, A.G. and Odersky, A. and Szymansky, A. and Seiler, M. and Althoff, K. and Beckers, A. and Speleman, F. and Schäfers, S. and De Preter, K. and Astrahanseff, K. and Struck, J. and Schramm, A. and Eggert, A. and Bergmann, A. and Schulte, J.H.
Oncotarget 8 (1): 430-443. 3 January 2017

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma.
Henssen, A. and Thor, T. and Odersky, A. and Heukamp, L. and El-Hindy, N. and Beckers, A. and Speleman, F. and Althoff, K. and Schäfers, S. and Schramm, A. and Sure, U. and Fleischhack, G. and Eggert, A. and Schulte, J.H.
Oncotarget 4 (11): 2080-2095. November 2013

Science Signaling

ALK pERKs up MYCN in neuroblastoma.
Lindner, S. and Henssen, A. and Astrahantseff, K. and Schulte, J.H.
Science Signaling 7 (349): pe27. 28 October 2014

Science Translational Medicine

Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.
Henssen, A.G. and Reed, C. and Jiang, E. and Garcia, H.D. and von Stebut, J. and MacArthur, I.C. and Hundsdoerfer, P. and Kim, J.H. and de Stanchina, E. and Kuwahara, Y. and Hosoi, H. and Ganem, N.J. and Dela Cruz, F. and Kung, A.L. and Schulte, J.H. and Petrini, J.H. and Kentsis, A.
Science Translational Medicine 9 (414): eaam9078. 1 November 2017

Translational Oncology

Small-molecule dual PLK1 and BRD4 inhibitors are active against preclinical models of pediatric solid tumors.
Timme, Natalie and Han, Youjia and Liu, Shuai and Yosief, Hailemichael O and García, Heathcliff Dorado and Bei, Yi and Klironomos, Filippos and MacArthur, Ian C and Szymansky, Annabell and von Stebut, Jennifer and Bardinet, Victor and Dohna, Constantin and Künkele, Annette and Rolff, Jana and Hundsdörfer, Patrick and Lissat, Andrej and Seifert, Georg and Eggert, Angelika and Schulte, Johannes H and Zhang, W. and Henssen, A.G.
Translational Oncology 13 (2): 221-232. February 2020

bioRxiv

Enhancer hijacking determines intra- and extrachromosomal circular MYCN amplicon architecture in neuroblastoma.
Helmsauer, Konstantin and Valieva, Maria and Ali, S. and Gonzalez, R.C. and Schöpflin, R. and Röefzaad, C. and Bei, Y. and Garcia, H.D. and Rodriguez-Fos, E. and Puiggròs, M. and Kasack, K. and Haase, K. and Kuschel, L.P. and Euskirchen, P. and Heinrich, V. and Robson, M. and Rosswog, C. and Tödling, J. and Szymansky, A. and Hertwig, F. and Fischer, M. and Torrents, D. and Eggert, A. and Schulte, J.H. and Mundlos, S. and Henssen, A.G. and Koche, R.P.
bioRxiv : 2019.12.20.875807. 20 December 2019

Partner-independent fusion gene detection by multiplexed CRISPR/Cas9 enrichment and long-read Nanopore sequencing.
Stangl, C. and de Blank, S. and Renkens, I. and Verbeek, T. and Valle-Inclan, J.E. and González, R.C. and Henssen, A.G. and van Roosmalen, M.J. and Stam, R.W. and Voest, E.E. and Kloosterman, W.P. and van Haaften, G. and Monroe, G.
bioRxiv : 807545. 22 October 2019

Prohibitin is a prognostic marker of relapse and therapeutic target to block chemotherapy resistance in Wilms tumor.
Ortiz, M.V. and Ahmed, S. and Burns, M. and Henssen, A.G. and Hollmann, T.J. and MacArthur, I. and Gunasekera, S. and Gaewsky, L. and Bradwin, G. and Ryan, J. and Letai, A. and He, Y. and Naranjo, A. and Chi, Y.Y. and LaQuaglia, M. and Heaton, T. and Cifani, P. and Dome, J.S. and Gadd, S. and Perlman, El. and Mullen, E. and Steen, H. and Kentsis, A.
bioRxiv : 508754. 30 December 2018

Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.
Henssen, A.G. and Reed, Casie and Jiang, Eileen and Garcia, H.D. and von Stebut, J. and MacArthur, I.C. and Hundsdoerfer, P. and Kim, J.H. and de Stanchina, E. and Kuwahara, Y. and Hosoi, H. and Ganem, N. and Cruz, F.D. and Kung, A.L. and Schulte, J.H. and Petrini, J.H. and Kentsis, A.
bioRxiv : 181040. 25 August 2017

Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors.
Henssen, A.G. and Koche, R. and Zhuang, J. and Jiang, E. and Reed, C. and Eisenberg, A. and Still, E. and MacArthur, I.C. and Rodríguez-Fos, E. and Gonzalez, S. and Puiggròs, M. and Blackford, A.N. and Mason, C.E. and de Stanchina, E. and Gönen, M. and Emde, An.K. and Shah, M. and Arora, K. and Reeves, C. and Socci, N.D. and Perlman, E. and Antonescu, C.R. and Roberts, C.W.M. and Steen, H. and Mullen, E. and Jackson, S.P. and Torrents, D. and Weng, Z. and Armstrong, S.A. and Kentsis, A.
bioRxiv : 111138. 23 February 2017

Forward genetic screen of human transposase genomic rearrangements.
Henssen, A.G. and Jiang, E. and Zhuang, J. and Pinello, L. and Socci, N.D. and Koche, R. and Gonen, M. and Villasante, C.M. and Armstrong, S.A. and Bauer, D.E. and Weng, Z. and Kentsis, A.
bioRxiv : 061770. 1 July 2016

Genomic DNA transposition induced by human PGBD5.
Henssen, A. and Henaff, E. and Jiang, E. and Eisenberg, A.R. and Carson, J.R. and Villasante, C. and Ray, M. and Still, E. and Burns, M. and Gandara, J. and Feschotte, C. and Mason, C.E. and Kentsis, A.
bioRxiv : 023887. 3 August 2015

eLife

Genomic DNA transposition induced by human PGBD5.
Henssen, A.G. and Henaff, E. and Jiang, E. and Eisenberg, A.R. and Carson, J.R. and Villasante, C.M. and Ray, M. and Still, E. and Burns, M. and Gandara, J. and Feschotte, C. and Mason, C.E. and Kentsis, A.
eLife 4 : e10565. 25 September 2015

This list was generated on Mon Aug 10 02:17:06 2020 CEST.
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