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A quantitative multi-parameter mapping protocol standardized for clinical research in multiple sclerosis.
Trang, H., Hartung, T.J., Chen, Q., Hetzer, S., Chien, C., Sperber, P.S., Schmitz-Hübsch, T., Asseyer, S., Rust, R., Mewes, D., Anderhalten, L., Sy, M., Brandt, A.U., Finke, C. and Paul, F.
Scientific Reports 14
(1): 30481.
16 December 2024
Adhesion of pancreatic tumor cell clusters by desmosomal molecules enhances early liver metastases formation.
Dietrich, N., Castellanos-Martinez, R., Kemmling, J., Heuser, A., Schnoor, M., Schinner, C. and Spindler, V.
Scientific Reports 14
(1): 18189.
6 August 2024
Establishment of a high-content compatible platform to assess effects of monocyte-derived factors on neural stem cell proliferation and differentiation.
Campo Garcia, J., Bueno, R.J., Salla, M., Martorell-Serra, I., Seeger, B., Akbari, N., Sperber, P., Stachelscheid, H., Infante-Duarte, C., Paul, F. and Starossom, S.C.
Scientific Reports 14
(1): 12167.
28 May 2024
Large‑scale assessment of physical activity in a population using high‑resolution hip‑worn accelerometry: the German National Cohort (NAKO).
Weber, A., van Hees, V.T., Stein, M.J., Gastell, S., Steindorf, K., Herbolsheimer, F., Ostrzinski, S., Pischon, T., Brandes, M., Krist, L., Marschollek, M., Greiser, K.H., Nimptsch, K., Brandes, B., Jochem, C., Sedlmeier, A.M., Berger, K., Brenner, H., Buck, C., Castell, S., Dörr, M., Emmel, C., Fischer, B., Flexeder, C., Harth, V., Hebestreit, A., Heise, J.K., Holleczek, B., Keil, T., Koch-Gallenkamp, L., Lieb, W., Meinke-Franze, C., Michels, K.B., Mikolajczyk, R., Kluttig, A., Obi, N., Peters, A., Schmidt, B., Schipf, S., Schulze, M.B., Teismann, H., Waniek, S., Willich, S.N., Leitzmann, M.F. and Baurecht, H.
Scientific Reports 14
(1): 7927.
4 April 2024
CD4+ T cell mitochondrial genotype in Multiple Sclerosis: a cross-sectional and longitudinal analysis.
Cortes-Figueiredo, F., Asseyer, S., Chien, C., Zimmermann, H.G., Ruprecht, K., Schmitz-Hübsch, T., Bellmann-Strobl, J., Paul, F. and Morais, V.A.
Scientific Reports 14
(1): 7507.
29 March 2024
Muscle stiffness indicating mission crew health in space.
Schoenrock, B., Muckelt, P.E., Hastermann, M., Albracht, K., MacGregor, R., Martin, D., Gunga, H.C., Salanova, M., Stokes, M.J., Warner, M.B. and Blottner, D.
Scientific Reports 14
(1): 4196.
20 February 2024
Anti-aquaporin-4 immune complex stimulates complement-dependent Th17 cytokine release in neuromyelitis optica spectrum disorders.
Nishiyama, S., Seok, J.M., Wright, A.E., Lotan, I., Mikami, T., Drosu, N.C., Bobrowski-Khoury, N., Anderson, M.R., Bilodeau, P.A., Schindler, P., Paul, F., Aoki, M., Yeaman, M.R. and Levy, M.
Scientific Reports 14
(1): 3146.
7 February 2024
Pregnancy associated plasma protein-A2 (PAPP-A2) and stanniocalcin-2 (STC2) but not PAPP-A are associated with circulating total IGF-1 in a human adult population.
Nimptsch, K., Aydin, E.E., Chavarria, R.F.R., Janke, J., Poy, M.N., Oxvig, C., Steinbrecher, A. and Pischon, T.
Scientific Reports 14
(1): 1770.
20 January 2024
Immediate reuse of patch-clamp pipettes after ultrasonic cleaning.
Jehasse, K., Jouhanneau, J.S., Wetz, S., Schwedt, A., Poulet, J.F.A., Neumann-Raizel, P. and Kampa, B.M.
Scientific Reports 14
(1): 1660.
18 January 2024
Automated image quality assessment for selecting among multiple magnetic resonance image acquisitions in the German National Cohort study.
Schuppert, C., Rospleszcz, S., Hirsch, J.G., Hoinkiss, D.C., Köhn, A., von Krüchten, R., Russe, M.F., Keil, T., Krist, L., Schmidt, B., Michels, K.B., Schipf, S., Brenner, H., Kröncke, T.J., Pischon, T., Niendorf, T., Schulz-Menger, J., Forsting, M., Völzke, H., Hosten, N., Bülow, R., Zaitsev, M., Kauczor, H.U., Bamberg, F., Günther, M. and Schlett, C.L.
Scientific Reports 13
(1): 22745.
20 December 2023
In vitro production of naked mole-rats' blastocysts from non-breeding females using in vitro maturation and intracytoplasmic sperm injection.
Simone, R., Čižmár, D., Holtze, S., Michel, G., Sporbert, A., Okolo, C. and Hildebrandt, T.B.
Scientific Reports 13
(1): 22355.
15 December 2023
Visualization and data exploration of chromosome conformation capture data using Voronoi diagrams with v3c-viz.
Race, A.M., Fuchs, A. and Chung, H.R.
Scientific Reports 13
(1): 22020.
12 December 2023
A bead-based multiplex assay covering all coronaviruses pathogenic for humans for sensitive and specific surveillance of SARS-CoV-2 humoral immunity.
Stern, D., Meyer, T.C., Treindl, F., Mages, H.W., Krüger, M., Skiba, M., Krüger, J.P., Zobel, C.M., Schreiner, M., Grossegesse, M., Rinner, T., Peine, C., Stoliaroff-Pépin, A., Harder, T., Hofmann, N., Michel, J., Nitsche, A., Stahlberg, S., Kneuer, A., Sandoni, A., Kubisch, U., Schlaud, M., Mankertz, A., Schwarz, T., Corman, V.M., Müller, M.A., Drosten, C., de la Rosa, K., Schaade, L., Dorner, M.B. and Dorner, B.G.
Scientific Reports 13
(1): 21846.
9 December 2023
Seropositivity of Borrelia burgdorferi s.l. in Germany-an analysis across four German National Cohort (NAKO) study sites.
Hassenstein, M.J., Pischon, T., Karch, A., Peters, A., Kerrinnes, T., Teismann, H., Schneider, A., Thierry, S., Moreno Velásquez, I., Janke, J., Kemmling, Y. and Castell, S.
Scientific Reports 13
(1): 21087.
30 November 2023
Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment.
Burmeister, T., Gröger, D., Gökbuget, N., Spriewald, B., Starck, M., Elmaagacli, A., Hoelzer, D., Keller, U. and Schwartz, S.
Scientific Reports 13
(1): 15167.
13 September 2023
Real-world evidence of ocrelizumab-treated relapsing multiple sclerosis cohort shows changes in progression independent of relapse activity mirroring phase 3 trials.
Ingwersen, J., Masanneck, L., Pawlitzki, M., Samadzadeh, S., Weise, M., Aktas, O., Meuth, S.G. and Albrecht, P.
Scientific Reports 13
(1): 15003.
11 September 2023
Predictors of lower exercise capacity in patients with cancer.
Evertz, R., Diehl, C., Gödde, K., Valentova, M., Garfias-Veitl, T., Overbeck, T.R., Braulke, F., Lena, A., Hadzibegovic, S., Bleckmann, A., Keller, U., Landmesser, U., König, A.O., Hasenfuss, G., Schuster, A., Anker, M.S. and von Haehling, S.
Scientific Reports 13
(1): 14861.
8 September 2023
The interleukin-11 receptor variant p.W307R results in craniosynostosis in humans.
Ahmad, I., Lokau, J., Kespohl, B., Malik, N.A., Baig, S.M., Hartig, R., Behme, D., Schwab, R., Altmüller, J., Jameel, M., Mucha, S., Thiele, H., Tariq, M., Nürnberg, P., Erdmann, J. and Garbers, C.
Scientific Reports 13
(1): 13479.
18 August 2023
Association of the human gut microbiota with vascular stiffness.
Cuadrat, R.R.C., Goris, T., Birukov, A., Eichelmann, F., Andrade, B.G.N., Bang, C., Franke, A., Wittenbecher, C. and Schulze, M.B.
Scientific Reports 13
(1): 13348.
16 August 2023
A weak-labelling and deep learning approach for in-focus object segmentation in 3D widefield microscopy.
Li, R., Kudryashev, M. and Yakimovich, A.
Scientific Reports 13
(1): 12275.
28 July 2023
Preoperative thalamus volume is not associated with preoperative cognitive impairment (preCI) or postoperative cognitive dysfunction (POCD).
Fislage, M., Feinkohl, I., Borchers, F., Pischon, T., Spies, C.D., Winterer, G. and Zacharias, N.
Scientific Reports 13
(1): 11732.
20 July 2023
Determining the structure of the bacterial voltage-gated sodium channel NaChBac embedded in liposomes by cryo electron tomography and subtomogram averaging.
Chang, S.Y.S., Dijkman, P.M., Wiessing, S.A. and Kudryashev, M.
Scientific Reports 13
: 11523.
17 July 2023
Translating principles of quality control to cardiovascular magnetic resonance: assessing quantitative parameters of the left ventricle in a large cohort.
Riazy, L., Däuber, S., Lange, S., Viezzer, D.S., Ott, S., Wiesemann, S., Blaszczyk, E., Mühlberg, F., Zange, L. and Schulz-Menger, J.
Scientific Reports 13
(1): 2205.
7 February 2023
Introduction of a cascaded segmentation pipeline for parametric T1 mapping in cardiovascular magnetic resonance to improve segmentation performance.
Viezzer, D., Hadler, T., Ammann, C., Blaszczyk, E., Fenski, M., Grandy, T.H., Wetzl, J., Lange, S. and Schulz-Menger, J.
Scientific Reports 13
(1): 2103.
6 February 2023
Obesity is associated with myelin oligodendrocyte glycoprotein antibody-associated disease in acute optic neuritis.
Stiebel-Kalish, H., Rubarth, K., Shouchane-Blum, K., Tiosano, A., Lotan, I., Hellmann, M.A., Wilf-Yarkoni, A., Bialer, O., Flanagan, E.P., Pittock, S.J., Bhatti, M.T., Schmitz-Hübsch, T., Paul, F., Asseyer, S. and Chen, J.J.
Scientific Reports 12
(1): 21312.
9 December 2022
Automated imaging-based abdominal organ segmentation and quality control in 20,000 participants of the UK Biobank and German National Cohort Studies.
Kart, T., Fischer, M., Winzeck, S., Glocker, B., Bai, W., Bülow, R., Emmel, C., Friedrich, L., Kauczor, H.U., Keil, T., Kröncke, T., Mayer, P., Niendorf, T., Peters, A., Pischon, T., Schaarschmidt, B.M., Schmidt, B., Schulze, M.B., Umutle, L., Völzke, H., Küstner, T., Bamberg, F., Schölkopf, B., Rueckert, D. and Gatidis, S.
Scientific Reports 12
(1): 18733.
4 November 2022
Widely applicable, extended flow cytometric stem cell enumeration panel for quality control of advanced cellular products.
Haussmann, K., Streitz, M., Takvorian, A., Grund, J., Skenderi, Z., Tietze-Bürger, C., Movassaghi, K., Künkele, A., Blum, A. and Bullinger, L.
Scientific Reports 12
(1): 17995.
26 October 2022
Structure-function correlates of vision loss in neuromyelitis optica spectrum disorders.
Gigengack, N.K., Oertel, F.C., Motamedi, S., Bereuter, C., Duchow, A., Rust, R., Bellmann‑Strobl, J., Ruprecht, K., Schmitz-Hübsch, T., Paul, F., Brandt, A.U. and Zimmermann, H.G.
Scientific Reports 12
(1): 17545.
20 October 2022
Mechanical properties of murine hippocampal subregions investigated by atomic force microscopy and in vivo magnetic resonance elastography.
Morr, A.S., Nowicki, M., Bertalan, G., Silva, R.V., Infante Duarte, C., Koch, S.P., Boehm-Sturm, P., Krügel, U., Braun, J., Steiner, B., Käs, J.A., Fuhs, T. and Sack, I.
Scientific Reports 12
(1): 16723.
6 October 2022
Prediction of activity-related energy expenditure under free-living conditions using accelerometer-derived physical activity.
Jeran, S., Steinbrecher, A., Haas, V., Mähler, A., Boschmann, M., Westerterp, K.R., Brühmann, B.A., Steindorf, K. and Pischon, T.
Scientific Reports 12
(1): 16578.
4 October 2022
Protocol and reference values for minimal detectable change of MyotonPRO and ultrasound imaging measurements of muscle and subcutaneous tissue.
Muckelt, P.E., Warner, M.B., Cheliotis-James, T., Muckelt, R., Hastermann, M., Schoenrock, B., Martin, D., MacGregor, R., Blottner, D. and Stokes, M.
Scientific Reports 12
(1): 13654.
11 August 2022
Disease relevance of rare VPS13B missense variants for neurodevelopmental Cohen syndrome.
Zorn, M., Kühnisch, J., Bachmann, S. and Seifert, W.
Scientific Reports 12
(1): 9686.
11 June 2022
Effects of separated pair housing of female C57BL/6JRj mice on well-being.
Hohlbaum, K., Merle, R., Frahm, S., Rex, A., Palme, R., Thöne-Reineke, C. and Ullmann, K.
Scientific Reports 12
(1): 8819.
25 May 2022
Analysis of adherent cell culture lysates with low metabolite concentrations using the Biocrates AbsoluteIDQ p400 HR kit.
Fritsche-Guenther, R., Gloaguen, Y., Eisenberger, A. and Kirwan, J.A.
Scientific Reports 12
(1): 7933.
13 May 2022
Motor signature of autism spectrum disorder in adults without intellectual impairment.
Cho, A.B., Otte, K., Baskow, I., Ehlen, F., Maslahati, T., Mansow-Model, S., Schmitz-Hübsch, T., Behnia, B. and Roepke, S.
Scientific Reports 12
(1): 7670.
10 May 2022
Myofibrillar protein synthesis rates are increased in chronically exercised skeletal muscle despite decreased anabolic signaling.
Langer, H.T., West, D., Senden, J., Spuler, S., van Loon, L.J.C. and Baar, K.
Scientific Reports 12
(1): 7553.
9 May 2022
Introduction of Lazy Luna an automatic software-driven multilevel comparison of ventricular function quantification in cardiovascular magnetic resonance imaging.
Hadler, T., Wetzl, J., Lange, S., Geppert, C., Fenski, M., Abazi, E., Gröschel, J., Ammann, C., Wenson, F., Töpper, A., Däuber, S. and Schulz-Menger, J.
Scientific Reports 12
(1): 6629.
22 April 2022
Expression of cardiovascular-related microRNAs is altered in L-arginine:glycine amidinotransferase deficient mice.
Jensen, M., Müller, C., Huebner, N., Patone, G., Saar, K., Choe, C.U., Schwedhelm, E. and Zeller, T.
Scientific Reports 12
(1): 5108.
24 March 2022
Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction.
Zywitza, V., Rusha, E., Shaposhnikov, D., Ruiz-Orera, J., Telugu, N., Rishko, V., Hayashi, M., Michel, G., Wittler, L., Stejskal, J., Holtze, S., Göritz, F., Hermes, R., Wang, J., Izsvák, Z., Colleoni, S., Lazzari, G., Galli, C., Hildebrandt, T.B., Hayashi, K., Diecke, S. and Drukker, M.
Scientific Reports 12
(1): 3100.
8 March 2022
Role of TRPC6 in kidney damage after acute ischemic kidney injury.
Zheng, Z., Tsvetkov, D., Bartolomaeus, T.U.P., Erdogan, C., Krügel, U., Schleifenbaum, J., Schaefer, M., Nürnberg, B., Chai, X., Ludwig, F.A., N'diaye, G., Köhler, M.B., Wu, K., Gollasch, M. and Markó, L.
Scientific Reports 12
(1): 3038.
22 February 2022
Improving robustness of automatic cardiac function quantification from cine magnetic resonance imaging using synthetic image data.
Gheorghiță, B.A., Itu, L.M., Sharma, P., Suciu, C., Wetzl, J., Geppert, C., Ali, M.A.A., Lee, A.M., Piechnik, S.K., Neubauer, S., Petersen, S.E., Schulz-Menger, J. and Chițiboi, T.
Scientific Reports 12
(1): 2391.
14 February 2022
Patch individual filter layers in CNNs to harness the spatial homogeneity of neuroimaging data.
Eitel, F., Albrecht, J.P., Weygandt, M., Paul, F. and Ritter, K.
Scientific Reports 11
(1): 24447.
27 December 2021
Anti-inflammatory role of Gpnmb in adipose tissue of mice.
Nickl, B., Qadri, F. and Bader, M.
Scientific Reports 11
(1): 19614.
4 October 2021
Chances and challenges of a long-term data repository in multiple sclerosis: 20th birthday of the German MS registry.
Ohle, L.M., Ellenberger, D., Flachenecker, P., Friede, T., Haas, J., Hellwig, K., Parciak, T., Warnke, C., Paul, F., Zettl, U.K. and Stahmann, A.
Scientific Reports 11
(1): 13340.
25 June 2021
Predicting lethal courses in critically ill COVID-19 patients using a machine learning model trained on patients with non-COVID-19 viral pneumonia.
Lichtner, G., Balzer, F., Haufe, S., Giesa, N., Schiefenhövel, F., Schmieding, M., Jurth, C., Kopp, W., Akalin, A., Schaller, S.J., Weber-Carstens, S., Spies, C. and von Dincklage, F.
Scientific Reports 11
(1): 13205.
24 June 2021
Transformation of SOX9(+) cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma.
Chen, J., Debebe, A., Zeng, N., Kopp, J., He, L., Sander, M. and Stiles, B.L.
Scientific Reports 11
(1): 11823.
3 June 2021
SIGLEC1 (CD169): a marker of active neuroinflammation in the brain but not in the blood of multiple sclerosis patients.
Ostendorf, L., Dittert, P., Biesen, R., Duchow, A., Stiglbauer, V., Ruprecht, K., Bellmann-Strobl, J., Seelow, D., Stenzel, W., Niesner, R.A., Hauser, A.E., Paul, F. and Radbruch, H.
Scientific Reports 11
(1): 10299.
13 May 2021
Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.
Franken, G.A.C., Seker, M., Bos, C., Siemons, L.A.H., van der Eerden, B.C.J., Christ, A., Hoenderop, J.G.J., Bindels, R.J.M., Müller, D., Breiderhoff, T. and de Baaij, J.H.F.
Scientific Reports 11
(1): 8217.
15 April 2021
Transverse aortic constriction induces gut barrier alterations, microbiota remodeling and systemic inflammation.
Boccella, N., Paolillo, R., Coretti, L., D'Apice, S., Lama, A., Giugliano, G., Schiattarella, G.G., Cuomo, M., d'Aquino, I., Cavaliere, G., Paciello, O., Mollica, M.P., Mattace Raso, G., Esposito, G., Lembo, F. and Perrino, C.
Scientific Reports 11
(1): 7404.
1 April 2021
PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice.
Messerschmidt, C., Foddis, M., Blumenau, S., Müller, S., Bentele, K., Holtgrewe, M., Kun-Rodrigues, C., Alonso, I., do Carmo Macario, M., Morgadinho, A.S., Velon, A.G., Santo, G., Santana, I., Mönkäre, S., Kuuluvainen, L., Schleutker, J., Pöyhönen, M., Myllykangas, L., Senatore, A., Berchtold, D., Winek, K., Meisel, A., Pavlovic, A., Kostic, V., Dobricic, V., Lohmann, E., Hanagasi, H., Guven, G., Bilgic, B., Bras, J., Guerreiro, R., Beule, D., Dirnagl, U. and Sassi, C.
Scientific Reports 11
(1): 6072.
16 March 2021
Dorsal raphe serotonin neurotransmission is required for the expression of nursing behavior and for pup survival.
Muzerelle, A., Soiza-Reilly, M., Hainer, C., Ruet, P.L., Lesch, K.P., Bader, M., Alenina, N., Scotto-Lomassese, S. and Gaspar, P.
Scientific Reports 11
(1): 6004.
16 March 2021
COVID-19: a simple statistical model for predicting intensive care unit load in exponential phases of the disease.
Ritter, M., Ott, D.V.M., Paul, F., Haynes, J.D. and Ritter, K.
Scientific Reports 11
(1): 5018.
3 March 2021
MTBP phosphorylation controls DNA replication origin firing.
Ferreira, P., Höfer, V., Kronshage, N., Marko, A., Reusswig, K.U., Tetik, B., Dießel, C., Köhler, K., Tschernoster, N., Altmüller, J., Schulze, N., Pfander, B. and Boos, D.
Scientific Reports 11
(1): 4242.
19 February 2021
Measuring myocardial extracellular volume of the right ventricle in patients with congenital heart disease.
Al-Wakeel-Marquard, N., Ferreira da Silva, T., Jeuthe, S., Rastin, S., Muench, F., O H-Ici, D., Yilmaz, S., Berger, F., Kuehne, T. and Messroghli, D.R.
Scientific Reports 11
(1): 2679.
29 January 2021
Phenotyping placental oxygenation in Lgals1 deficient mice using (19)F MRI.
Boehm-Sturm, P., Mueller, S., Freitag, N., Borowski, S., Foddis, M., Koch, S.P., Temme, S., Flögel, U. and Blois, S.M.
Scientific Reports 11
(1): 2126.
22 January 2021
Genetic information from discordant sibling pairs points to ESRP2 as a candidate trans-acting regulator of the CF modifier gene SCNN1B.
Becker, T., Pich, A., Tamm, S., Hedtfeld, S., Ibrahim, M., Altmüller, J., Dalibor, N., Toliat, M.R., Janciauskiene, S., Tümmler, B. and Stanke, F.
Scientific Reports 10
(1): 22447.
31 December 2020
Assessment of nanoindentation in stiffness measurement of soft biomaterials: kidney, liver, spleen and uterus.
Wu, G., Gotthardt, M. and Gollasch, M.
Scientific Reports 10
(1): 18784.
2 November 2020
Species-specific differences in synaptic transmission and plasticity.
Beed, P., Ray, S., Velasquez, L.M., Stumpf, A., Parthier, D., Swaminathan, A., Nitzan, N., Breustedt, J., Las, L., Brecht, M. and Schmitz, D.
Scientific Reports 10
(1): 16557.
6 October 2020
A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort.
Christakoudi, S., Tsilidis, K.K., Muller, D.C., Freisling, H., Weiderpass, E., Overvad, K., Söderberg, S., Häggström, C., Pischon, T., Dahm, C.C., Zhang, J., Tjønneland, A., Halkjær, J., MacDonald, C., Boutron-Ruault, M.C., Mancini, F.R., Kühn, T., Kaaks, R., Schulze, M.B., Trichopoulou, A., Karakatsani, A., Peppa, E., Masala, G., Pala, V., Panico, S., Tumino, R., Sacerdote, C., Quirós, J.R., Agudo, A., Sánchez, M.J., Cirera, L., Barricarte-Gurrea, A., Amiano, P., Memarian, E., Sonestedt, E., Bueno-de-Mesquita, B., May, A.M., Khaw, K.T., Wareham, N.J., Tong, T.Y.N., Huybrechts, I., Noh, H., Aglago, E.K., Ellingjord-Dale, M., Ward, H.A., Aune, D. and Riboli, E.
Scientific Reports 10
(1): 14541.
3 September 2020
Effects of empagliflozin and target-organ damage in a novel rodent model of heart failure induced by combined hypertension and diabetes.
Kräker, K., Herse, F., Golic, M., Reichhart, N., Crespo-Garcia, S., Straß, O., Grune, J., Kintscher, U., Ebrahim, M., Bader, M., Alenina, N., Heuser, A., Luft, F.C., Müller, D.N., Dechend, R. and Haase, N.
Scientific Reports 10
(1): 14061.
20 August 2020
Non-thermal effects of radiofrequency electromagnetic fields.
Wust, P., Kortüm, B., Strauss, U., Nadobny, J., Zschaeck, S., Beck, M., Stein, U. and Ghadjar, P.
Scientific Reports 10
(1): 13488.
10 August 2020
Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients.
Lauber, C., Correia, N., Trumpp, A., Rieger, M.A., Dolnik, A., Bullinger, L., Roeder, I. and Seifert, M.
Scientific Reports 10
(1): 12761.
29 July 2020
Induced pluripotent stem cells of patients with Tetralogy of Fallot reveal transcriptional alterations in cardiomyocyte differentiation.
Grunert, M., Appelt, S., Schönhals, S., Mika, K., Cui, H., Cooper, A., Cyganek, L., Guan, K. and Sperling, S.R.
Scientific Reports 10
(1): 10921.
2 July 2020
Association of body surface scanner-based abdominal volume with parameters of the Metabolic Syndrome and comparison with manually measured waist circumference.
Jaeschke, L., Steinbrecher, A., Hansen, G., Sommer, S., Adler, C., Janke, J. and Pischon, T.
Scientific Reports 10
(1): 9324.
9 June 2020
CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development.
Aherrahrou, R., Kulle, A.E., Alenina, N., Werner, R., Vens-Cappell, S., Bader, M., Schunkert, H., Erdmann, J. and Aherrahrou, Z.
Scientific Reports 10
(1): 8792.
29 May 2020
Lipid mediator profiles predict response to therapy with an oral frankincense extract in relapsing-remitting multiple sclerosis.
Stürner, K.H., Werz, O., Koeberle, A., Otto, M., Pless, O., Leypoldt, F., Paul, F. and Heesen, C.
Scientific Reports 10
(1): 8776.
29 May 2020
Investigating APOE, APP-Aβ metabolism genes and Alzheimer's disease GWAS hits in brain small vessel ischemic disease.
Blumenau, S., Foddis, M., Müller, S., Holtgrewe, M., Bentele, K., Berchtold, D., Beule, D., Dirnagl, U. and Sassi, C.
Scientific Reports 10
(1): 7103.
28 April 2020
N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma.
Tjaden, B., Baum, K., Marquardt, V., Simon, M., Trajkovic-Arsic, M., Kouril, T., Siebers, B., Lisec, J., Siveke, J.T., Schulte, J.H., Benary, U., Remke, M., Wolf, J. and Schramm, A.
Scientific Reports 10
(1): 7157.
28 April 2020
Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1.
Jupp, B., Pitzoi, S., Petretto, E., Mar, A.C., Oliver, Y.P., Jordan, E.R., Taylor, S., Atanur, S.S., Srivastava, P.K., Saar, K., Hubner, N., Sommer, W.H., Staehlin, O., Spanagel, R., Robinson, E.S., Schumann, G., Moreno, M., Everitt, B.J., Robbins, T.W., Aitman, T.J. and Dalley, J.W.
Scientific Reports 10
(1): 6684.
21 April 2020
Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue.
Grunwald, S.A., Popp, O., Haafke, S., Jedraszczak, N., Grieben, U., Saar, K., Patone, G., Kress, W., Steinhagen-Thiessen, E., Dittmar, G. and Spuler, S.
Scientific Reports 10
: 2158.
7 February 2020
Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates.
Langer, H.T., Afzal, S., Kempa, S. and Spuler, S.
Scientific Reports 10
: 1908.
5 February 2020
Factors associated with habitual time spent in different physical activity intensities using multiday accelerometry.
Jaeschke, L., Steinbrecher, A., Boeing, H., Gastell, S., Ahrens, W., Berger, K., Brenner, H., Ebert, N., Fischer, B., Greiser, K.H., Hoffmann, W., Jöckel, K.H., Kaaks, R., Keil, T., Kemmling, Y., Kluttig, A., Krist, L., Leitzmann, M., Lieb, W., Linseisen, J., Löffler, M., Michels, K.B., Obi, N., Peters, A., Schipf, S., Schmidt, B., Zinkhan, M. and Pischon, T.
Scientific Reports 10
: 774.
21 January 2020
Proteomic and transcriptomic changes in hibernating grizzly bears reveal metabolic and signaling pathways that protect against muscle atrophy.
Mugahid, D.A., Sengul, T.G., You, X., Wang, Y., Steil, L., Bergmann, N., Radke, M.H., Ofenbauer, A., Gesell-Salazar, M., Balogh, A., Kempa, S., Tursun, B., Robbins, C.T., Völker, U., Chen, W., Nelson, L. and Gotthardt, M.
Scientific Reports 9
(1): 19976.
27 December 2019
Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses.
Maglione, M., Kochlamazashvili, G., Eisenberg, T., Rácz, B., Michael, E., Toppe, D., Stumpf, A., Wirth, A., Zeug, A., Müller, F.E., Moreno-Velasquez, L., Sammons, R.P., Hofer, S.J., Madeo, F., Maritzen, T., Maier, N., Ponimaskin, E., Schmitz, D., Haucke, V. and Sigrist, S.J.
Scientific Reports 9
(1): 19616.
23 December 2019
Diffusion-weighted renal MRI at 9.4 Tesla using RARE to improve anatomical integrity.
dos Santos Periquito, J., Paul, K., Huelnhagen, T., Ku, M.C., Ji, Y., Cantow, K., Gladytz, T., Grosenick, D., Flemming, B., Seeliger, E., Waiczies, S., Niendorf, T. and Pohlmann, A.
Scientific Reports 9
(1): 19723.
23 December 2019
Multi-parameter immune profiling of peripheral blood mononuclear cells by multiplexed single-cell mass cytometry in patients with early multiple sclerosis.
Böttcher, C., Fernández-Zapata, C., Schlickeiser, S., Kunkel, D., Schulz, A.R., Mei, H.E., Weidinger, C., Gieß, R.M., Asseyer, S., Siegmund, B., Paul, F., Ruprecht, K. and Priller, J.
Scientific Reports 9
(1): 19471.
19 December 2019
Altered microRNA and target gene expression related to tetralogy of fallot.
Grunert, M., Appelt, S., Dunkel, I., Berger, F. and Sperling, S.R.
Scientific Reports 9
(1): 19063.
13 December 2019
Contactless recording of sleep apnea and periodic leg movements by nocturnal 3-D-video and subsequent visual perceptive computing.
Veauthier, C., Ryczewski, J., Mansow-Model, S., Otte, K., Kayser, B., Glos, M., Schöbel, C., Paul, F., Brandt, A.U. and Penzel, T.
Scientific Reports 9
(1): 16812.
14 November 2019
Dietary protein restriction throughout intrauterine and postnatal life results in potentially beneficial myocardial tissue remodeling in the adult mouse heart.
Hennig, M., Ewering, L., Pyschny, S., Shimoyama, S., Olecka, M., Ewald, D., Magarin, M., Uebing, A., Thierfelder, L., Jux, C. and Drenckhahn, J.D.
Scientific Reports 9
(1): 15126.
22 October 2019
Genotyping of circulating tumor DNA in cholangiocarcinoma reveals diagnostic and prognostic information.
Ettrich, T.J., Schwerdel, D., Dolnik, A., Beuter, F., Blätte, T.J., Schmidt, S.A., Stanescu-Siegmund, N., Steinacker, J., Marienfeld, R., Kleger, A., Bullinger, L., Seufferlein, T. and Berger, A.W.
Scientific Reports 9
(1): 13261.
13 September 2019
TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor.
Klein, S., Kleine, C.E., Pieper, A., Granzow, M., Gautsch, S., Himmit, M., Kahrmann, K., Schierwagen, R., Uschner, F.E., Magdaleno, F., Naoum, M.E., Kristiansen, Glen, Walther, T., Bader, M., Sauerbruch, T. and Trebicka, J.
Scientific Reports 9
(1): 11598.
12 August 2019
The association between frailty and MRI features of cerebral small vessel disease.
Kant, I.M.J., Mutsaerts, H.J.M.M., van Montfort, S.J.T., Jaarsma-Coes, M.G., Witkamp, T.D., Winterer, G., Spies, C.D., Hendrikse, J., Slooter, A.J.C. and de Bresser, J.
Scientific Reports 9
(1): 11343.
5 August 2019
Characterization of bacterial communities in wastewater with enhanced taxonomic resolution by full-length 16S rRNA sequencing.
Numberger, D., Ganzert, L., Zoccarato, L., Mühldorfer, K., Sauer, S., Grossart, H.P. and Greenwood, A.D.
Scientific Reports 9
(1): 9673.
4 July 2019
Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB/W F1 mice.
Klocke, J., Ulu, A., Wu, K., Rudolph, B., Dragun, D., Gollasch, M., Schunck, W.H., Hammock, B.D., Riemekasten, G. and Enghard, P.
Scientific Reports 9
(1): 8993.
20 June 2019
Systemic outcomes of (Pyr(1))-apelin-13 infusion at mid-late pregnancy in a rat model with preeclamptic features.
Yamaleyeva, L.M., Brosnihan, K.B., Elsangeedy, E., McGee, C., Shi, S., Caudell, D., Miller, C., Varagic, J., Bader, M., Dechend, R. and Shaltout, H.A.
Scientific Reports 9
(1): 8579.
12 June 2019
Calcyphosine-like (CAPSL) is regulated in multiple symmetric lipomatosis and is involved in adipogenesis.
Lindner, A., Marbach, F., Tschernitz, S., Ortner, C., Berneburg, M., Felthaus, O., Prantl, L., Kye, M.J., Rappl, G., Altmüller, J., Thiele, H., Schreml, S. and Schreml, J.
Scientific Reports 9
(1): 8444.
11 June 2019
The cell adhesion protein CAR is a negative regulator of synaptic transmission.
Wrackmeyer, U., Kaldrack, J., Jüttner, R., Pannasch, U., Gimber, N., Freiberg, F., Purfürst, B., Kainmueller, D., Schmitz, D., Haucke, V., Rathjen, F.G. and Gotthardt, M.
Scientific Reports 9
(1): 6768.
1 May 2019
The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.
Funk, N., Munz, M., Ott, T., Brockmann, K., Wenninger-Weinzierl, A., Kühn, R., Vogt-Weisenhorn, D., Giesert, F., Wurst, W., Gasser, T. and Biskup, S.
Scientific Reports 9
(1): 4515.
14 March 2019
Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures.
Schroeder, M.P., Bastian, L., Eckert, C., Gökbuget, N., James, A.R., Ortiz Tanchez, J., Schlee, C., Isaakidis, K., Häupl, B., Baum, K., Migueles Lozano, O.A., Kouidri, K., Pan, K.T., Urlaub, H., Schwartz, S., Burmeister, T., von Stackelberg, A., Hoelzer, D., Pfeiffer, H., Rieger, M.A., Göllner, S., Oellerich, T., Horstman, M., Schrappe, M., Wolf, J., Kirschner-Schwabe, R., Brüggemann, M., Müller-Tidow, C., Serve, H., Neumann, M. and Baldus, C.D.
Scientific Reports 9
(1): 4188.
12 March 2019
MTrack: automated detection, tracking, and analysis of dynamic microtubules.
Kapoor, V., Hirst, W.G., Hentschel, C., Preibisch, S. and Reber, S.
Scientific Reports 9
(1): 3794.
7 March 2019
A transcriptome-wide analysis deciphers distinct roles of G1 cyclins in temporal organization of the yeast cell cycle.
Teufel, L., Tummler, K., Flöttmann, M., Herrmann, A., Barkai, N. and Klipp, E.
Scientific Reports 9
(1): 3343.
4 March 2019
Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress.
Jochner, M.C.E., An, J., Lättig-Tünnemann, G., Kirchner, M., Dagane, A., Dittmar, G., Dirnagl, U., Eickholt, B.J. and Harms, C.
Scientific Reports 9
(1): 3183.
28 February 2019
Anoctamin-4 is a bona fide Ca(2+)-dependent non-selective cation channel.
Reichhart, N., Schöberl, S., Keckeis, S., Alfaar, A.S., Roubeix, C., Cordes, M., Crespo-Garcia, S., Haeckel, A., Kociok, N., Föckler, R., Fels, G., Mataruga, A., Rauh, R., Milenkovic, V.M., Zühlke, K., Klussmann, E., Schellenberger, E. and Strauß, O.
Scientific Reports 9
(1): 2257.
19 February 2019
Multisite de novo mutations in human offspring after paternal exposure to ionizing radiation.
Holtgrewe, M., Knaus, A., Hildebrand, G., Pantel, J.T., de los Santos, M.R., Neveling, K., Goldmann, J., Schubach, M., Jäger, M., Coutelier, M., Mundlos, S., Beule, D., Sperling, K. and Krawitz, P.M.
Scientific Reports 8
(1): 14611.
2 October 2018
Pancreatic exocrine tissue architecture and integrity are maintained by e-cadherin during postnatal development.
Serrill, J.D., Sander, M. and Shih, H.P.
Scientific Reports 8
(1): 13451.
7 September 2018
Nuclear pore complex components in the malaria parasite Plasmodium berghei.
Kehrer, J., Kuss, C., Andres-Pons, A., Reustle, A., Dahan, N., Devos, D., Kudryashev, M., Beck, M., Mair, G.R. and Frischknecht, F.
Scientific Reports 8
(1): 11249.
26 July 2018
Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission - The THYROID Project.
Kopp, S., Krüger, M., Feldmann, S., Oltmann, H., Schütte, A., Schmitz, B., Bauer, J., Schulz, H., Saar, K., Hübner, N., Wehland, M., Nassef, M.Z., Melnik, D., Meltendorf, S., Infanger, M. and Grimm, D.
Scientific Reports 8
(1): 10355.
9 July 2018
Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Fritsche-Guenther, R., Zasada, C., Mastrobuoni, G., Royla, N., Rainer, R., Roßner, F., Pietzke, M., Klipp, E., Sers, C. and Kempa, S.
Scientific Reports 8
(1): 9204.
15 June 2018
The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse.
Bégay, V., Baumeier, C., Zimmermann, K., Heuser, A. and Leutz, A.
Scientific Reports 8
(1): 8417.
30 May 2018
Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.
Gonçalves, I.C.G., Brecht, J., Thelen, M.P., Rehorst, W.A., Peters, M., Lee, H.J., Motameny, S., Torres-Benito, L., Ebrahimi-Fakhari, D., Kononenko, N.L., Altmüller, J., Vilchez, D., Sahin, M., Wirth, B. and Kye, M.J.
Scientific Reports 8
(1): 7907.
21 May 2018
Cardiac pacemaker channel (HCN4) inhibition and atrial arrhythmogenesis after releasing cardiac sympathetic activation.
Chobanyan-Jürgens, K., Heusser, K., Duncker, D., Veltmann, C., May, M., Mehling, H., Luft, F.C., Schröder, C., Jordan, J. and Tank, J.
Scientific Reports 8
(1): 7748.
17 May 2018
Molecular details of dimerization kinetics reveal negligible populations of transient µ-opioid receptor homodimers at physiological concentrations.
Meral, D., Provasi, D., Prada-Gracia, D., Möller, J., Marino, K., Lohse, M.J. and Filizola, M.
Scientific Reports 8
(1): 7705.
16 May 2018
Transient receptor potential vanilloid 4 channel deficiency aggravates tubular damage after acute renal ischaemia reperfusion.
Mannaa, M., Markó, L., Balogh, A., Vigolo, E., N'diaye, G., Kaßmann, M., Michalick, L., Weichelt, U., Schmidt-Ott, K.M., Liedtke, W.B., Huang, Y., Müller, D.N., Kuebler, W.M. and Gollasch, M.
Scientific Reports 8
(1): 4878.
20 March 2018
Single molecule real time sequencing in ADTKD-MUC1 allows complete assembly of the VNTR and exact positioning of causative mutations.
Wenzel, A., Altmueller, J., Ekici, A.B., Popp, B., Stueber, K., Thiele, H., Pannes, A., Staubach, S., Salido, E., Nuernberg, P., Reinhardt, R., Reis, A., Rump, P., Hanisch, F.G., Wolf, M.T.F., Wiesener, M., Huettel, B. and Beck, B.B.
Scientific Reports 8
(1): 4170.
8 March 2018
Myocardial effective transverse relaxation time T(2)* is elevated in hypertrophic cardiomyopathy: a 7.0 T magnetic resonance imaging study.
Huelnhagen, T., Ku, M.C., Reimann, H.M., Serradas Duarte, T., Pohlmann, A., Flemming, B., Seeliger, E., Eichhorn, C., Ferrari, V.A., Prothmann, M., Schulz-Menger, J. and Niendorf, T.
Scientific Reports 8
(1): 3974.
5 March 2018
Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs).
Lagies, S., Pichler, R., Kaminski, M.M., Schlimpert, M., Walz, G., Lienkamp, S.S. and Kammerer, B.
Scientific Reports 8
(1): 3878.
1 March 2018
Loss-of-function uORF mutations in human malignancies.
Schulz, J., Mah, N., Neuenschwander, M., Kischka, T., Ratei, R., Schlag, P.M., Castaños-Vélez, E., Fichtner, I., Tunn, P.U., Denkert, C., Klaas, O., Berdel, W.E., von Kries, J.P., Makalowski, W., Andrade-Navarro, M.A., Leutz, A. and Wethmar, K.
Scientific Reports 8
(1): 2395.
5 February 2018
Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.
Franko, A., Rodriguez Camargo, D.C., Böddrich, A., Garg, D., Rodriguez Camargo, A., Rathkolb, B., Janik, D., Aichler, M., Feuchtinger, A., Neff, F., Fuchs, H., Wanker, E.E., Reif, B., Häring, H.U., Peter, A. and Hrabě de Angelis, M.
Scientific Reports 8
(1): 1116.
18 January 2018
The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine.
Kopp, S., Sahana, J., Islam, T., Petersen, A.G., Bauer, J., Corydon, T.J., Schulz, H., Saar, K., Huebner, N., Slumstrup, L., Riwaldt, S., Wehland, M., Infanger, M., Luetzenberg, R. and Grimm, D.
Scientific Reports 8
(1): 921.
17 January 2018
Serotonin regulates prostate growth through androgen receptor modulation.
Carvalho-Dias, E., Miranda, A., Martinho, O., Mota, P., Costa, A., Nogueira-Silva, C., Moura, R.S., Alenina, N., Bader, M., Autorino, R., Lima, E. and Correia-Pinto, J.
Scientific Reports 7
(1): 15428.
13 November 2017
Open source 3D multipurpose measurement system with submillimetre fidelity and first application in magnetic resonance.
Han, H., Moritz, R., Oberacker, E., Waiczies, H., Niendorf, T. and Winter, L.
Scientific Reports 7
(1): 13452.
18 October 2017
Immunoproteasome subunit β5i/LMP7-deficiency in atherosclerosis.
Hewing, B., Ludwig, A., Dan, C., Poetzsch, M., Hannemann, C., Petry, A., Lauer, D., Görlach, A., Kaschina, E., Müller, D.N., Baumann, G., Stangl, V., Stangl, K. and Wilck, N.
Scientific Reports 7
(1): 13342.
17 October 2017
Cryo-EM studies of Drp1 reveal cardiolipin interactions that activate the helical oligomer.
Francy, C.A., Clinton, R.W., Froehlich, C., Murphy, C. and Mears, J.A.
Scientific Reports 7
(1): 10744.
6 September 2017
Pregnancy-associated plasma protein-A2 and anthropometry, lifestyle, and biochemical factors in a human adult population.
Steinbrecher, A., Janke, J., Poy, M.N., Oxvig, C. and Pischon, T.
Scientific Reports 7
(1): 10455.
5 September 2017
Enhanced fluorine-19 MRI sensitivity using a cryogenic radiofrequency probe: technical developments and ex vivo demonstration in a mouse model of neuroinflammation.
Waiczies, S., Millward, J.M., Starke, L., Delgado, P.R., Huelnhagen, T., Prinz, C., Marek, D., Wecker, D., Wissmann, R., Koch, S.P., Boehm-Sturm, P., Waiczies, H., Niendorf, T. and Pohlmann, A.
Scientific Reports 7
(1): 9808.
29 August 2017
Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain.
DiCara, D.M., Chirgadze, D.Y., Pope, A.R., Karatt-Vellatt, A., Winter, A., Slavny, P., van den Heuvel, J., Parthiban, K., Holland, J., Packman, L.C., Mavria, G., Hoffmann, J., Birchmeier, W., Gherardi, E. and McCafferty, J.
Scientific Reports 7
(1): 9000.
21 August 2017
β1-adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes.
Park, M., Reddy, G.R., Wallukat, G., Xiang, Y.K. and Steinberg, S.F.
Scientific Reports 7
(1): 7890.
11 August 2017
Nijmegen Breakage Syndrome fibroblasts and iPSCs: cellular models for uncovering disease-associated signaling pathways and establishing a screening platform for anti-oxidants.
Mlody, B., Wruck, W., Martins, S., Sperling, K. and Adjaye, J.
Scientific Reports 7
(1): 7516.
8 August 2017
Synergistic strategy for multicolor two-photon microscopy: application to the analysis of germinal center reactions in vivo.
Rakhymzhan, A., Leben, R., Zimmermann, H., Günther, R., Mex, P., Reismann, D., Ulbricht, C., Acs, A., Brandt, A.U., Lindquist, R.L., Winkler, T.H., Hauser, A.E. and Niesner, R.A.
Scientific Reports 7
(1): 7101.
2 August 2017
Mapping the dynamics of the glucocorticoid receptor within the nuclear landscape.
Stortz, M., Presman, D.M., Bruno, L., Annibale, P., Dansey, M.V., Burton, G., Gratton, E., Pecci, A. and Levi, V.
Scientific Reports 7
(1): 6219.
24 July 2017
Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes.
Jäger, S., Wahl, S., Kröger, J., Sharma, S., Hoffmann, P., Floegel, A., Pischon, T., Prehn, C., Adamski, J., Müller-Nurasyid, M., Waldenberger, M., Strauch, K., Peters, A., Gieger, C., Suhre, K., Grallert, H., Boeing, H., Schulze, M.B. and Meidtner, K.
Scientific Reports 7
(1): 6037.
20 July 2017
Congenital deafness is associated with specific somatosensory deficits in adolescents.
Moshourab, R., Bégay, V., Wetzel, C., Walcher, J., Middleton, S., Gross, M. and Lewin, G.R.
Scientific Reports 7
(1): 4251.
26 June 2017
24 h-accelerometry in epidemiological studies : automated detection of non-wear time in comparison to diary information.
Jaeschke, L., Luzak, A., Steinbrecher, A., Jeran, S., Ferland, M., Linkohr, B., Schulz, H. and Pischon, T.
Scientific Reports 7
(1): 2227.
22 May 2017
The developmental emergence of differential brainstem serotonergic control of the sensory spinal cord.
Schwaller, F., Kanellopoulos, A.H. and Fitzgerald, M.
Scientific Reports 7
(1): 2215.
22 May 2017
A deep intronic CLRN1 (USH3A) founder mutation generates an aberrant exon and underlies severe Usher syndrome on the Arabian Peninsula.
Khan, A.O., Becirovic, E., Betz, C., Neuhaus, C., Altmüller, J., Maria Riedmayr, L., Motameny, S., Nürnberg, G., Nürnberg, P. and Bolz, H.J.
Scientific Reports 7
(1): 1411.
3 May 2017
Sensitization of glioblastoma tumor micro-environment to chemo- and immunotherapy by Galectin-1 intranasal knock-down strategy.
Van Woensel, M., Mathivet, T., Wauthoz, N., Rosière, R., Garg, A.D., Agostinis, P., Mathieu, V., Kiss, R., Lefranc, F., Boon, L., Belmans, J., Van Gool, S.W., Gerhardt, H., Amighi, K. and De Vleeschouwer, S.
Scientific Reports 7
(1): 1217.
27 April 2017
Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
Mönke, G., Cristiano, E., Finzel, A., Friedrich, D., Herzel, H., Falcke, M. and Loewer, A.
Scientific Reports 7
: 46571.
18 April 2017
TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents.
Wallmeyer, L., Dietert, K., Sochorová, M., Gruber, A.D., Kleuser, B., Vávrová, K. and Hedtrich, S.
Scientific Reports 7
(1): 774.
4 April 2017
The redox environment triggers conformational changes and aggregation of hIAPP in type II diabetes.
Rodriguez Camargo, D.C., Tripsianes, K., Buday, K., Franko, A., Göbl, C., Hartlmüller, C., Sarkar, R., Aichler, M., Mettenleiter, G., Schulz, M., Böddrich, A., Erck, C., Martens, H., Walch, A.K., Madl, T., Wanker, E.E., Conrad, M., de Angelis, M.H. and Reif, B.
Scientific Reports 7
: 44041.
13 March 2017
Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis.
Dianzani, C., Bellavista, E., Liepe, J., Verderio, Cl., Martucci, M., Santoro, A., Chiocchetti, A., Luca Gigliotti, C., Boggio, E., Ferrara, B., Riganti, L., Keller, C., Janek, K., Niewienda, A., Fenoglio, C., Sorosina, M., Cantello, R., Kloetzel, P.M., Stumpf, M.P.H., Paul, F., Ruprecht, K., Galimberti, D., Martinelli Boneschi, F., Comi, C., Dianzani, U. and Mishto, M.
Scientific Reports 7
: 43718.
9 March 2017
Signatures of personality on dense 3D facial images.
Hu, S., Xiong, J., Fu, P., Qiao, L., Tan, J., Jin, L. and Tang, K.
Scientific Reports 7
(1): 73.
March 2017
Characterization of the CD177 interaction with the ANCA antigen proteinase 3.
Jerke, U., Marino, S.F., Daumke, O. and Kettritz, R.
Scientific Reports 7
: 43328.
27 February 2017
Rapid adaptation to microgravity in mammalian macrophage cells.
Thiel, C.S., de Zélicourt, D., Tauber, S., Adrian, A., Franz, M., Simmet, D.M., Schoppmann, K., Hauschild, S., Krammer, S., Christen, M., Bradacs, G., Paulsen, K., Wolf, S.A., Braun, M., Hatton, J., Kurtcuoglu, V., Franke, S., Tanner, S., Cristoforetti, S., Sick, B., Hock, B. and Ullrich, O.
Scientific Reports 7
(1): 43.
27 February 2017
Investigation of hippocampal synaptic transmission and plasticity in mice deficient in the actin-binding protein Drebrin.
Willmes, C.G., Mack, T.G.A., Ledderose, J., Schmitz, D., Wozny, C. and Eickholt, B.J.
Scientific Reports 7
: 42652.
15 February 2017
Lipidome determinants of maximal lifespan in mammals.
Bozek, K., Khrameeva, E.E., Reznick, J., Omerbašić, D., Bennett, N.C., Lewin, G.R., Azpurua, J., Gorbunova, V., Seluanov, A., Regnard, P., Wanert, F., Marchal, J., Pifferi, F., Aujard, F., Liu, Z., Shi, P., Pääbo, S., Schroeder, F., Willmitzer, L., Giavalisco, P. and Khaitovich, P.
Scientific Reports 7
: 5.
31 January 2017
Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders.
Hadar, R., Edemann-Callesen, H., Reinel, C., Wieske, F., Voget, M., Popova, E., Sohr, R., Avchalumov, Y., Priller, J., van Riesen, C., Puls, I., Bader, M. and Winter, C.
Scientific Reports 6
: 39145.
15 December 2016
The mutation p.E113K in the Schiff base counterion of rhodopsin is associated with two distinct retinal phenotypes within the same family.
Reiff, C., Owczarek-Lipska, M., Spital, G., Röger, C., Hinz, H., Jüschke, C., Thiele, H., Altmüller, J., Nürnberg, P., Da Costa, R. and Neidhardt, J.
Scientific Reports 6
: 36208.
4 November 2016
Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain.
Ventéo, S., Laffray, S., Wetzel, C., Rivat, C., Scamps, F., Méchaly, I., Bauchet, L., Raoul, C., Bourinet, E., Lewin, G.R., Carroll, P. and Pattyn, A.
Scientific Reports 6
: 36407.
2 November 2016
Neprilysin is a mediator of alternative renin-angiotensin-system activation in the murine and human kidney.
Domenig, O., Manzel, A., Grobe, N., Königshausen, E., Kaltenecker, C.C., Kovarik, J.J., Stegbauer, J., Gurley, S.B., van Oyen, D., Antlanger, M., Bader, M., Motta-Santos, D., Santos, R.A., Elased, K.M., Säemann, M.D., Linker, R.A. and Poglitsch, M.
Scientific Reports 6
: 33678.
21 September 2016
Generation of functional cardiomyocytes from the synoviocytes of patients with rheumatoid arthritis via induced pluripotent stem cells.
Lee, J., Jung, S.M., Ebert, A.D., Wu, H., Diecke, S., Kim, Y., Yi, H., Park, S.H. and Ju, J.H.
Scientific Reports 6
: 32669.
9 September 2016
ANGIOGENES: knowledge database for protein-coding and noncoding RNA genes in endothelial cells.
Mueller, R., Weirick, T., John, D., Militello, G., Chen, W., Dimmeler, S. and Uchida, S.
Scientific Reports 6
: 32475.
1 September 2016
Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18.
Flegel, C., Vogel, F., Hofreuter, A., Wojcik, S., Schoeder, C., Kieć-Kononowicz, K., Brockmeyer, N.H., Müller, C.E., Becker, C., Altmüller, J., Hatt, H. and Gisselmann, G.
Scientific Reports 6
: 32255.
30 August 2016
Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream.
Langenfurth, A., Gu, S., Bautze, V., Zhang, C., Neumann, J.E., Schüller, U., Stock, K., Wolf, S.A., Maier, A.M., Mastrella, G., Pak, A., Cheng, H., Kälin, R.E., Holmbeck, K., Strotmann, J., Kettenmann, H. and Glass, R.
Scientific Reports 6
: 32203.
30 August 2016
The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.
Batalha, V.L., Ferreira, D.G., Coelho, J.E., Valadas, J.S., Gomes, R., Temido-Ferreira, M., Shmidt, T., Baqi, Y., Buée, L., Müller, C.E., Hamdane, M., Outeiro, T.F., Bader, M., Meijsing, S.H., Sadri-Vakili, G., Blum, D. and Lopes, L.V.
Scientific Reports 6
: 31493.
11 August 2016
Acute effects of ferumoxytol on regulation of renal hemodynamics and oxygenation.
Cantow, K., Pohlmann, A., Flemming, B., Ferrara, F., Waiczies, S., Grosenick, D., Niendorf, T. and Seeliger, E.
Scientific Reports 6
: 29965.
20 July 2016
Role of cystathionine gamma-lyase in immediate renal impairment and inflammatory response in acute ischemic kidney injury.
Markó, L., Szijártó, I.A., Filipovic, M.R., Kaßmann, M., Balogh, A., Park, J.K., Przybyl, L., N'diaye, G., Krämer, S., Anders, J., Ishii, I., Müller, D.N. and Gollasch, M.
Scientific Reports 6
: 27517.
8 June 2016
Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes.
Ebstein, F., Textoris-Taube, K., Keller, C., Golnik, R., Vigneron, N., Van den Eynde, B.J., Schuler-Thurner, B., Schadendorf, D., Lorenz, F.K.M., Uckert, W., Urban, S., Lehmann, A., Albrecht-Koepke, N., Janek, K., Henklein, P., Niewienda, A., Kloetzel, P.M. and Mishto, M.
Scientific Reports 6
: 24032.
6 April 2016
Kcne2 deletion causes early-onset nonalcoholic fatty liver disease via iron deficiency anemia.
Lee, S.M., Nguyen, D., Anand, M., Kant, R., Koehncke, C., Lisewski, U., Roepke, T.K., Hu, Z. and Abbott, G.W.
Scientific Reports 6
: 23118.
17 March 2016
Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.
Jung, B., Messias, A.C., Schorpp, K., Geerlof, A., Schneider, G., Saur, D., Hadian, K., Sattler, M., Wanker, E.E., Hasenöder, S. and Lickert, H.
Scientific Reports 6
: 22540.
2 March 2016
Normothermic mouse functional MRI of acute focal thermostimulation for probing nociception.
Reimann, H.M., Hentschel, J., Marek, J., Huelnhagen, T., Todiras, M., Kox, S., Waiczies, S., Hodge, R., Bader, M., Pohlmann, A. and Niendorf, T.
Scientific Reports 6
: 17230.
29 January 2016
PCNA appears in two populations of slow and fast diffusion with a constant ratio throughout S-phase in replicating mammalian cells.
Zessin, P.J.M., Sporbert, A. and Heilemann, M.
Scientific Reports 6
: 18779.
13 January 2016
A probabilistic model for estimating the depth and threshold temperature of C-fiber nociceptors.
Dezhdar, T., Moshourab, R.A., Fründ, I., Lewin, G.R. and Schmuker, M.
Scientific Reports 5
: 17670.
7 December 2015
Multiple sources of infection and potential endemic characteristics of the large outbreak of dengue in Guangdong in 2014.
Shen, S.Q., Wei, H.X., Fu, Y.H., Zhang, H., Mo, Q.Y., Wang, X.J., Deng, S.Q., Zhao, W., Liu, Y., Feng, X.S., Chen, W. and Peng, H.J.
Scientific Reports 5
: 16913.
23 November 2015
Aβ42-oligomer Interacting Peptide (AIP) neutralizes toxic amyloid-β42 species and protects synaptic structure and function.
Barucker, C., Bittner, H.J., Chang, P.K.Y., Cameron, S., Hancock, M.A., Liebsch, F., Hossain, S., Harmeier, A., Shaw, H., Charron, F.M., Gensler, M., Dembny, P., Zhuang, W., Schmitz, D., Rabe, J.P., Rao, Y., Lurz, R., Hildebrand, P.W., McKinney, R.A. and Multhaup, G.
Scientific Reports 5
: 15410.
29 October 2015
Epoxides derived from dietary dihomo-gamma-linolenic acid induce germ cell death in C. elegans.
Deline, M., Keller, J., Rothe, M., Schunck, W.H., Menzel, R. and Watts, J.L.
Scientific Reports 5
: 15417.
21 October 2015
Specific microRNAs regulate heat stress responses in Caenorhabditis elegans.
Nehammer, C., Podolska, A., Mackowiak, S.D., Kagias, K. and Pocock, R.
Scientific Reports 5
: 8866.
9 March 2015
Comparative analysis of KRAS codon 12, 13, 18, 61, and 117 mutations using human MCF10A isogenic cell lines.
Stolze, B., Reinhart, S., Bullinger, L., Fröhling, S. and Scholl, C.
Scientific Reports 5
: 8535.
23 February 2015
Anchoring dipalmitoyl phosphoethanolamine to nanoparticles boosts cellular uptake and fluorine-19 magnetic resonance signal.
Waiczies, S., Lepore, S., Sydow, K., Drechsler, S., Ku, M.C., Martin, C., Lorenz, D., Schütz, I., Reimann, H.M., Purfürst, B., Dieringer, M.A., Waiczies, H., Dathe, M., Pohlmann, A. and Niendorf, T.
Scientific Reports 5
: 8427.
12 February 2015
Novel codon-optimized mini-intronic plasmid for efficient, inexpensive, and xeno-free induction of pluripotency.
Diecke, S., Lu, J., Lee, J., Termglinchan, V., Kooreman, N.G., Burridge, P.W., Ebert, A.D., Churko, J.M., Sharma, A., Kay, M.A. and Wu, J.C.
Scientific Reports 5
: 8081.
28 January 2015
Moderate inappropriately high aldosterone/NaCl constellation in mice: cardiovascular effects and the role of cardiovascular epidermal growth factor receptor.
Schreier, B., Rabe, S., Winter, S., Ruhs, S., Mildenberger, S., Schneider, B., Sibilia, M., Gotthardt, M., Kempe, S., Mäder, K., Grossmann, C. and Gekle, M.
Scientific Reports 4
: 7430.
11 December 2014
Further improvements to linear mixed models for genome-wide association studies.
Widmer, C., Lippert, C., Weissbrod, O., Fusi, N., Kadie, C., Davidson, R., Listgarten, J. and Heckerman, D.
Scientific Reports 4
: 6874.
12 November 2014
The benefits of selecting phenotype-specific variants for applications of mixed models in genomics.
Lippert, C., Quon, G., Kang, E.Y., Kadie, C.M., Listgarten, J. and Heckerman, D.
Scientific Reports 3
: 1815.
9 May 2013
Visualizing brain inflammation with a shingled-leg radio-frequency head probe for (19)F/(1)H MRI.
Waiczies, H., Lepore, S., Drechsler, S., Qadri, F., Purfürst, B., Sydow, K., Dathe, M., Kühne, A., Lindel, T., Hoffmann, W., Pohlmann, A., Niendorf, T. and Waiczies, S.
Scientific Reports 3
: 1280.
15 February 2013
An exhaustive epistatic SNP association analysis on expanded Wellcome Trust data.
Lippert, C., Listgarten, J., Davidson, R.I., Baxter, J., Poon, H., Kadie, C.M. and Heckerman, D.
Scientific Reports 3
: 1099.
22 January 2013
Cold-induced RNA-binding proteins regulate circadian gene expression by controlling alternative polyadenylation.
Liu, Y., Hu, W., Murakawa, Y., Yin, J., Wang, G., Landthaler, M. and Yan, J.
Scientific Reports 3
: 2054.
2013
Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain.
Rogelj, B., Easton, L.E., Bogu, G.K., Stanton, L.W., Rot, G., Curk, T., Zupan, B., Sugimoto, Y., Modic, M., Haberman, N., Tollervey, J., Fujii, R., Takumi, T., Shaw, C.E. and Ule, J.
Scientific Reports 2
: 603.
28 August 2012
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