Helmholtz Gemeinschaft

Search
Browse
Statistics
Feeds

Browse by Research Team

Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: Date | Item Type | Source

Article

Structural investigation of glycan recognition by the ERAD quality control lectin Yos9.
Kniss, A. and Kazemi, S. and Löhr, F. and Berger, M. and Rogov, V.V. and Güntert, P. and Sommer, T. and Jarosch, E. and Dötsch, V.
Journal of Biomolecular NMR 72 (1-2): 1-10. October 2018

Chain assembly and disassembly processes differently affect the conformational space of ubiquitin chains.
Kniss, A. and Schuetz, D. and Kazemi, S. and Pluska, L. and Spindler, P.E. and Rogov, V.V. and Husnjak, K. and Dikic, I. and Güntert, P. and Sommer, T. and Prisner, T.F. and Dötsch, V.
Structure 26 (2): 249-258. 6 February 2018

Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity.
Wetzel, C. and Pifferi, S. and Picci, C. and Gök, C. and Hoffmann, D. and Bali, K.K. and Lampe, A. and Lapatsina, L. and Fleischer, R. and Smith, E.S.J. and Bégay, V. and Moroni, M. and Estebanez, L. and Kühnemund, J. and Walcher, J. and Specker, E. and Neuenschwander, M. and von Kries, J.P. and Haucke, V. and Kuner, R. and Poulet, J.F.A. and Schmoranzer, J. and Poole, K. and Lewin, G.R.
Nature Neuroscience 20 (2): 209-218. February 2017

OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation.
Barrera, M. and Koob, S. and Dikov, D. and Vogel, F. and Reichert, A.S.
FEBS Letters 590 (19): 3309-3322. October 2016

Sequential poly-ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase.
Weber, A. and Cohen, I. and Popp, O. and Dittmar, G. and Reiss, Y. and Sommer, T. and Ravid, T. and Jarosch, E.
Molecular Cell 63 (5): 827-839. 1 September 2016

Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination.
Braten, O. and Livneh, I. and Ziv, T. and Admon, A. and Kehat, I. and Caspi, L.H. and Gonen, H. and Bercovich, B. and Godzik, A. and Jahandideh, S. and Jaroszewski, L. and Sommer, T. and Kwon, Y.T. and Guharoy, M. and Tompa, P. and Ciechanover, A.
Proceedings of the National Academy of Sciences of the United States of America 113 (32): E4639-E4647. 9 August 2016

The CUE domain of Cue1 aligns growing ubiquitin chains with Ubc7 for rapid elongation.
von Delbrück, M. and Kniss, A. and Rogov, V.V. and Pluska, L. and Bagola, K. and Löhr, F. and Güntert, P. and Sommer, T. and Dötsch, V.
Molecular Cell 62 (6): 918-928. 16 June 2016

A complex of Htm1 and the oxidoreductase Pdi1 accelerates degradation of misfolded glycoproteins.
Pfeiffer, A. and Stephanowitz, H. and Krause, E. and Volkwein, C. and Hirsch, C. and Jarosch, E. and Sommer, T.
Journal of Biological Chemistry 291 (23): 12195-12207. 3 June 2016

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.
Lodka, D. and Pahuja, A. and Geers-Knörr, C. and Scheibe, R. and Nowak, M. and Hamati, J. and Köhncke, C. and Purfürst, B. and Kanashova, T. and Schmidt, S. and Glass, D.J. and Morano, I. and Heuser, A. and Kraft, T. and Bassel-Duby, R. and Olson, E.N. and Dittmar, G. and Sommer, T. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7 (2): 165-180. May 2016

KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth.
Kravtsova-Ivantsiv, Y. and Shomer, I. and Cohen-Kaplan, V. and Snijder, B. and Superti-Furga, G. and Gonen, H. and Sommer, T. and Ziv, T. and Admon, A. and Naroditsky, I. and Jbara, M. and Brik, A. and Pikarsky, E. and Kwon, Y.T. and Doweck, I. and Ciechanover, A.
Cell 161 (2): 333-347. 9 April 2015

Disassembly of Lys11- and mixed-linkage polyubiquitin conjugates provide insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.
Mansour, W. and Nakasone, M.A. and von Delbrück, M. and Yu, Z. and Krutauz, D. and Reis, N. and Kleifeld, O. and Sommer, T. and Fushman, D. and Glickman, M.H.
Journal of Biological Chemistry 290 (8): 4688-4704. 20 February 2015

The interplay of Hrd3 and the molecular chaperone system ensures efficient degradation of malfolded secretory proteins.
Mehnert, M. and Sommermeyer, F. and Berger, M. and Lakshmipathy, S.K. and Gauss, R. and Aebi, M. and Jarosch, E. and Sommer, T.
Molecular Biology of the Cell 26 (2): 185-194. 15 January 2015

Hexosamine pathway metabolites enhance protein quality control and prolong life.
Denzel, M.S. and Storm, N.J. and Gutschmidt, A. and Baddi, R. and Hinze, Y. and Jarosch, E. and Sommer, T. and Hoppe, T. and Antebi, A.
Cell 156 (6): 1167-1178. 13 March 2014

Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane.
Mehnert, M. and Sommer, T. and Jarosch, E.
Nature Cell Biology 16 (1): 77-86. January 2014

Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Bagola, K. and von Delbrück, M. and Dittmar, G. and Scheffner, M. and Ziv, I. and Glickman, M.H. and Ciechanover, A. and Sommer, T.
Molecular Cell 50 (4): 528-539. 23 May 2013

The lysine48-based polyubiquitin chain proteasomal signal: not a single child anymore.
Kravtsova-Ivantsiv, Y. and Sommer, T. and Ciechanover, A.
Angewandte Chemie International Edition 52 (1): 192-198. 2 January 2013

The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation.
Shabek, N. and Herman-Bachinsky, Y. and Buchsbaum, S. and Lewinson, O. and Haj-Yahya, M. and Hejjaoui, M. and Lashuel, H.A. and Sommer, T. and Brik, A. and Ciechanover, A.
Molecular Cell 48 (1): 87-97. 12 October 2012

The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Finley, D. and Ulrich, H.D. and Sommer, T. and Kaiser, P.
Genetics 192 (2): 319-360. 1 October 2012

Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex.
Hanna, J. and Schütz, A. and Zimmermann, F. and Behlke, J. and Sommer, T. and Heinemann, U.
Journal of Biological Chemistry 287 (11): 8633-8640. 9 March 2012

Yos9p assists in the degradation of certain non-glycosylated proteins from the endoplasmic reticulum.
Jaenicke, L.A. and Brendebach, H. and Selbach, M. and Hirsch, C.
Molecular Biology of the Cell 22 (16): 2937-2945. August 2011

Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
Horn, S.C. and Hanna, J. and Hirsch, C. and Volkwein, C. and Schütz, A. and Heinemann, U. and Sommer, T. and Jarosch, E.
Molecular Cell 36 (5): 782-793. 11 December 2009

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation.
Lutz, A.K. and Exner, N. and Fett, M.E. and Schlehe, J.S. and Kloos, K. and Laemmermann, K. and Brunner, B. and Kurz-Drexler, A. and Vogel, F. and Reichert, A.S. and Bouman, L. and Vogt-Weisenhorn, D. and Wurst, W. and Tatzelt, J. and Haass, C. and Winklhofer, K.F.
Journal of Biological Chemistry 284 (34): 22938-22951. 21 August 2009

Distinct roles of the two isoforms of the dynamin-like GTPase Mgm1 in mitochondrial fusion.
Zick, M. and Duvezin-Caubet, S. and Schaefer, A. and Vogel, F. and Neupert, W. and Reichert, A.S.
FEBS Letters 583 (13): 2237-2243. 7 July 2009

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g.
Rabl, R. and Soubannier, V. and Scholz, R. and Vogel, F. and Mendl, N. and Vasiljev-Neumeyer, A. and Koerner, C. and Jagasia, R. and Keil, T. and Baumeister, W. and Cyrklaff, M. and Neupert, W. and Reichert, A.S.
Journal of Cell Biology 185 (6): 1047-1063. 15 June 2009

Mrpl36 is important for generation of assembly competent proteins during mitochondrial translation.
Prestele, M. and Vogel, F. and Reichert, A.S. and Herrmann, J.M. and Ott, M.
Molecular Biology of the Cell 20 (10): 2615-2625. May 2009

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum.
Clerc, S. and Hirsch, C. and Oggier, D.M. and Deprez, P. and Jakob, C. and Sommer, T. and Aebi, M.
Journal of Cell Biology 184 (1): 159-172. 12 January 2009

The nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast.
Neuber, A. and Franke, J. and Wittstruck, A. and Schlenstedt, G. and Sommer, T. and Stade, K.
Molecular and Cellular Biology 28 (17): 5348-5358. September 2008

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.
Exner, N. and Treske, B. and Paquet, D. and Holmstroem, K. and Schiesling, C. and Gispert, S. and Carballo-Carbajal, I. and Berg, D. and Hoepken, H.H. and Gasser, T. and Krueger, R. and Winklhofer, K.F. and Vogel, F. and Reichert, A.S. and Auburger, G. and Kahle, P.J. and Schmid, B. and Haass, C.
Journal of Neuroscience 27 (45): 12413-12418. 7 November 2007

Topoisomerase II binds importin alpha isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells.
Mirski, S.E.L. and Sparks, K.E. and Friedrich, B. and Koehler, M. and Mo, Y.Y. and Beck, W.T. and Cole, S.P.C.
Experimental Cell Research 313 (3): 627-637. 1 February 2007

Nuclear localization signal and protein context both mediate importin α specificity of nuclear import substrates.
Friedrich, B. and Quensel, C. and Sommer, T. and Hartmann, E. and Koehler, M.
Molecular and Cellular Biology 26 (23): 8697-8709. December 2006

Dynamic subcompartmentalization of the mitochondrial inner membrane.
Vogel, F. and Bornhoevd, C. and Neupert, W. and Reichert, A.S.
Journal of Cell Biology 175 (2): 237-247. 23 October 2006

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.
Gauss, R. and Jarosch, E. and Sommer, T. and Hirsch, C.
Nature Cell Biology 8 (8): 849-854. August 2006

Mitochondrial membrane potential is dependent on the oligomeric state of F1F0-ATP synthase supracomplexes.
Bornhoevd, C. and Vogel, F. and Neupert, W. and Reichert, A.S.
Journal of Biological Chemistry 281 (20): 13990-13998. 19 May 2006

The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment.
Gauss, R. and Sommer, T. and Jarosch, E.
EMBO Journal 25 (9): 1827-1835. 3 May 2006

Ubx2 links the Cdc48 complex to ER-associated protein degradation.
Neuber, O. and Jarosch, E. and Volkwein, C. and Walter, J. and Sommer, T.
Nature Cell Biology 7 (10): 993-998. 18 September 2005

Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast.
Dimmer, K.S. and Jakobs, S. and Vogel, F. and Altmann, K. and Westermann, B.
Journal of Cell Biology 168 (1): 103-115. 3 January 2005

NF-κB is transported into the nucleus by importin α3 and importin α4.
Fagerlund, R. and Kinnunen, L. and Koehler, M. and Julkunen, I. and Melen, K.
Journal of Biological Chemistry 280 (16): 15942-15951. 1 January 2005

New modules for the repeated internal and N-terminal epitope tagging of genes in Saccharomyces cerevisiae.
Gauss, R. and Trautwein, M. and Sommer, T. and Spang, A.
Yeast 22 (1): 1-12. 1 January 2005

Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization.
Turnbull, A.P. and Kuemmel, D. and Prinz, B. and Holz, C. and Schultchen, J. and Lang, C. and Niesen, F.H. and Hofmann, K.P. and Delbrueck, H. and Behlke, J. and Mueller, E.C. and Jarosch, E. and Sommer, T. and Heinemann, U.
EMBO Journal 24 (5): 875-884. 1 January 2005

In vivo analysis of importin alpha proteins reveals cellular proliferation inhibition and substrate specificity.
Quensel, C. and Friedrich, B. and Sommer, T. and Hartmann, E. and Koehler, M.
Molecular and Cellular Biology 24 (23): 10246-10255. 1 January 2004

Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation.
Meusser, B. and Sommer, T.
Molecular Cell 14 (2): 247-258. 1 January 2004

The inner membrane protein Mdm33 controls mitochondrial morphology in yeast.
Messerschmitt, M. and Jakobs, S. and Vogel, F. and Fritz, S. and Dimmer, K.S. and Neupert, W. and Westermann, B.
Journal of Cell Biology 160 (4): 553-564. 18 February 2003

Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA.
Herlan, M. and Vogel, F. and Boernhovd, C. and Neupert, W. and Reichert, A.S.
Journal of Biological Chemistry 278 (30): 27781-27788. 1 January 2003

ER-Golgi traffic is a prerequisite for efficient ER degradation.
Taxis, C. and Vogel, F. and Wolf, D.H.
Molecular Biology of the Cell 13 (6): 1806-1818. 1 June 2002

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex.
Fujita, Y. and Krause, G. and Scheffner, M. and Zechner, D. and Leddy, H.E.M. and Behrens, J. and Sommer, T. and Birchmeier, W.
Nature Cell Biology 4 (3): 222-231. 1 March 2002

Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.
Jarosch, E. and Taxis, C. and Volkwein, C. and Bordallo, J. and Finley, D. and Wolf, D.H. and Sommer, T.
Nature Cell Biology 4 (2): 134-139. 1 February 2002

A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast.
Stade, K. and Vogel, F. and Schwienhorst, I. and Meusser, B. and Volkwein, C. and Nentwig, B. and Dohmen, R.J. and Sommer, T.
Journal of Biological Chemistry 277 (51): 49554-49561. 1 January 2002

A role for mammalian Ubc6 homologues in ER-associated protein degradation.
Lenk, U. and Yu, H. and Walter, J. and Gelman, M.S. and Hartmann, E. and Kopito, R.R. and Sommer, T.
Journal of Cell Science 115 (14): 3007-3014. 1 January 2002

Functional expression of GFP-linked human heart sodium channel (hH1) and subcellular localization of the alpha subunit in HEK293 cells and dog cardiac myocytes.
Zimmer, T. and Biskup, C. and Dugarmaa, S. and Vogel, F. and Steinbis, M. and Boehle, T. and Wu, Y.S. and Dumaine, R. and Benndorf, K.
Journal of Membrane Biology 186 (1): 1-12. 1 January 2002

Functional expression of human mitochondrial CYP11B2 in fission yeast and identification of a new internal electron transfer protein, etp1.
Bureik, M. and Schiffler, B. and Hiraoka, Y. and Vogel, F. and Bernhardt, R.
Biochemistry 41 (7): 2311-2321. 1 January 2002

Renal anaemia of an unusual origin.
Koehler, M. and Schneider, W. and Goebel, U. and Kettritz, R.
Nephrology Dialysis Transplantation 16 (11): 2263-2264. November 2001

The nuclear export receptor Xpo1p forms distinct complexes with NES transport substrates and the yeast ran binding protein 1 (Yrb1p).
Maurer, P. and Redd, M. and Solsbacher, J. and Bischoff, F.R. and Greiner, M. and Podtelejnikov, A.V. and Mann, M. and Stade, K. and Weis, K. and Schlenstedt, G.
Molecular Biology of the Cell 12 (3): 539-549. March 2001

Adenoviral E1A protein nuclear import is preferentially mediated by importin alpha3 in vitro.
Koehler, M. and Goerlich, D. and Hartmann, E. and Franke, J.
Virology 289 : 186-191. 1 January 2001

Evidence for a nuclear passage of nascent polypeptide-associated complex subunits in yeast.
Franke, J. and Reimann, B. and Hartmann, E. and Koehler, M. and Wiedmann, B.
Journal of Cell Science 114 : 2641-2648. 1 January 2001

Increased importin alpha protein expression in diabetic nephropathy.
Koehler, M. and Buchwalow, I.B. and Alexander, G. and Christiansen, M. and Shagdarsuren, E. and Samoilova, V. and Hartmann, E. and Mervaala, E.M.A. and Haller, H.
Kidney International 60 : 2263-2273. 1 January 2001

Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p.
Walter, J. and Urban, J. and Volkwein, C. and Sommer, T.
EMBO Journal 20 (12): 3124-3131. 1 January 2001

Thyroid hormone regulates the obesity gene tub.
Koritschoner, N.P. and Alvarez-Dolado, M. and Kurz, S.M. and Heikenwaelder, M.F. and Hacker, C. and Vogel, F. and Munoz, A. and Zenke, M.
EMBO Reports 2 (6): 499-504. 1 January 2001

Dendritic cells conditionally transformed by v-relER oncogene express lymphoid marker genes.
Madruga, J. and Briegel, K. and Diebold, S. and Boehmelt, G. and Vogel, F. and Zenke, M.
Immunobiology 202 (4): 394-407. 1 November 2000

Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin alpha.
Solsbacher, J. and Maurer, P. and Vogel, F. and Schlenstedt, G.
Molecular and Cellular Biology 20 (22): 8468-8479. 1 November 2000

A regulatory link between ER-associated protein degradation and the unfolded-protein response.
Friedlander, R. and Jarosch, E. and Urban, J. and Volkwein, C. and Sommer, T.
Nature Cell Biology 2 (7): 379-384. 1 July 2000

Purification of Saccharomcyes cerevisiae mitochondria devoid of microsomal and cytosolic contaminations.
Meisinger, C. and Sommer, T. and Pfanner, N.
Analytical Biochemistry 287 (2): 339-342. 1 January 2000

Ubiquitin-mediated proteolysis of a short lived regulatory protein depends on its cellular localization.
Lenk, U. and Sommer, T.
Journal of Biological Chemistry 275 (50): 39403-39410. 1 January 2000

RanBP3 contains an unusual nuclear localization signal that is imported preferentially by importin-alpha3.
Welch, K. and Franke, J. and Koehler, M. and Macara, I.G.
Molecular and Cellular Biology 19 (12): 8400-8411. December 1999

Yeast cells allow high-level expression and formation of polyomavirus-like particles.
Sasnauskas, K. and Buzaite, O. and Vogel, F. and Jandrig, B. and Razanskas, R. and Staniulis, J. and Scherneck, S. and Kruger, D.H. and Ulrich, R.
Biological Chemistry 380 : 381-386. 1 March 1999

Regulation of endoplasmic reticulum biogenesis in response to cytochrome P450 overproduction.
Sandig, G. and Kaergel, E. and Menzel, R. and Vogel, F. and Zimmer, T. and Schunck, W.H.
Drug Metabolism Reviews 31 : 393-410. 1 January 1999

Urokinase-induced mitogenesis is mediated by casein kinase 2 and nucleolin.
Dumler, I. and Stepanova, V. and Jerke, U. and Mayboroda, O.A. and Vogel, F. and Bouvet, P. and Tkachuk, V. and Haller, H. and Gulba, D.C.
Current Biology 9 : 1468-1476. 1 January 1999

Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle.
Finley, D. and Tanaka, K. and Mann, C. and Feldmann, H. and Hochstrasser, M. and Vierstra, R. and Johnston, S. and Hampton, R. and Haber, J. and Mccusker, J. and Silver, P. and Frontali, L. and Thorsness, P. and Varshavsky, A. and Byers, B. and Madura, K. and Reed, S.I. and Wolf, D. and Jentsch, S. and Sommer, T. and Baumeister, W. and Goldberg, A. and Fried, V. and Rubin, D.M. and Toh-e, A.
Trends in Biochemical Sciences 23 (7): 244-245. 1 July 1998

Role of Cue1p in ubiquitination and degradition at the ER surface.
Biederer, T. and Volkwein, C. and Sommer, T.
Science 278 (5344): 1806-1809. 5 December 1997

Inducible membranes in yeast: relations to the unfolded-protein-response pathway.
Menzel, R. and Vogel, F. and Kaergel, E. and Schunck, W.H.
Yeast 13 : 1211-1229. 1 January 1997

Introduction of plasmid DNA into isolated mitochondria by electroporation. A novel approach toward gene correction for mitochondrial disorders.
Collombet, J.M. and Wheeler, V.C. and Vogel, F. and Coutelle, C.
Journal of Biological Chemistry 272 : 5342-5347. 1 January 1997

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation.
Plemper, R.K. and Bohmler, S. and Bordallo, J. and Sommer, T. and Wolf, D.H.
Nature 388 : 891-895. 1 January 1997

Protein quality - a determinant of the intracellular fate of membrane-bound cytochromes P450 in yeast.
Zimmer, T. and Vogel, F. and Ohta, A. and Takagi, M. and Schunck, W.H.
DNA and Cell Biology 16 : 501-514. 1 January 1997

The Srp40 protein plays a dose-sensitive role in preribosome assembly or transport and depends on its carboxy-terminal domain for proper localization to the yeast nucleoskeleton.
Ikonomova, R. and Sommer, T. and Kepes, F.
DNA and Cell Biology 16 : 1161-1173. 1 January 1997

Importin provides a link between nuclear protein import and U snRNA export.
Goerlich, D. and Kraft, R. and Kostka, S. and Vogel, F. and Hartmann, E. and Laskey, R.A. and Mattaj, I.W. and Izaurralde, E.
Cell 87 (1): 21-32. 4 October 1996

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.
Ruiz, P. and Brinkmann, V. and Ledermann, B. and Behrend, M. and Grund, C. and Thalhammer, C. and Vogel, F. and Birchmeier, C. and Guenthert, U. and Franke, W.W. and Birchmeier, W.
Journal of Cell Biology 135 (1): 215-225. October 1996

A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S.cerevisiae.
Finke, K. and Plath, K. and Panzner, S. and Prehn, S. and Rapoport, T.A. and Hartmann, E. and Sommer, T.
EMBO Journal 15 (7): 1482-1494. 1 January 1996

Candida maltosa NADPH-cytochrome P450 reductase: cloning of a full-length cDNA, heterologous expression in Saccharomyces cerevisiae and function of the N-terminal region for membrane anchoring and proliferation of the endoplasmic reticulum.
Kaergel, E. and Menzel, R. and Honeck, H. and Vogel, F. and Boehmer, A. and Schunck, W.H.
Yeast 12 : 333-348. 1 January 1996

Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway.
Biederer, T. and Volkwein, C. and Sommer, T.
EMBO Journal 15 : 2069-2076. 1 January 1996

Topogenesis of a microsomal cytochrome P450 and induction of endoplasmic reticulum membrane proliferation in Saccharomyces cerevisiae.
Menzel, R. and Kaergel, E. and Vogel, F. and Boettcher, C. and Schunck, W.H.
Archives of Biochemistry and Biophysics 330 : 97-109. 1 January 1996

VIP21-Caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro.
Monier, S. and Parton, R.G. and Vogel, F. and Behlke, J. and Henske, A. and Kurzchalia, T.V.
Molecular Biology of the Cell 6 (7): 911-927. July 1995

Distinct functions for the two importin subunits in nuclear protein import.
Goerlich, D. and Vogel, F. and Mills, A.D. and Hartmann, E. and Laskey, R.A.
Nature 377 : 246-248. 1 January 1995

In vivo reconstitution of highly active Candida maltosa cytochrome P450 monooxygenase systems in inducible membranes of Saccharomyces cerevisiae.
Zimmer, T. and Kaminski, K. and Scheller, U. and Vogel, F. and Schunck, W.H.
DNA and Cell Biology 14 : 619-628. 1 January 1995

Proliferation of intracellular membrane structures upon homologous overproduction of cytochrome P-450 in Candida maltosa.
Ohkuma, M. and Park, S.M. and Zimmer, T. and Menzel, R. and Vogel, F. and Schunck, W.H. and Ohta, A. and Takagi, M.
Biochimica et Biophysica Acta 1236 (1): 163-169. 1 January 1995

Evolutionary conservation of components of the protein translocation complex.
Hartmann, E. and Sommer, T. and Prehn, S. and Goerlich, D. and Jentsch, S. and Rapoport, T.A.
Nature 367 : 654-657. 1 January 1994

Production of monoclonal antibodies against epitopes of the main coat protein of filamentous fd phages.
Micheel, B. and Heymann, S. and Scharte, G. and Boettger, V. and Vogel, F. and Duebel, S. and Breitling, F. and Little, M. and Behrsing, O.
Journal of Immunological Methods 71 : 103-109. 1 January 1994

Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATalpha2 repressor.
Chen, P. and Johnson, P. and Sommer, T. and Jentsch, S. and Hochstrasser, M.
Cell 74 (2): 357-369. 30 July 1993

A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum.
Sommer, T. and Jentsch, S.
Nature 365 : 176-179. 1 January 1993

Immunocytochemical localization of alkane-inducible cytochrome P-450 and its NADPH-dependet reductase in the yeast Candida maltosa.
Vogel, F. and Gengnagel, C. and Kaergel, E. and Mueller, H.G. and Schunck, W.H.
European Journal of Cell Biology 57 : 285-291. 1 January 1992

Comparison of two cytochromes P-450 from Candida maltosa: primary structures, substrate specificities, and effects of their expression in Saccharomyces cerevisoae on the proliferation of the endoplasmic reticulum.
Schunck, W.H. and Vogel, F. and Gross, B. and Kaergel, E. and Mauersberger, S. and Koepke, K. and Gengnagel, C. and Mueller, H.G.
European Journal of Cell Biology 55 : 336-345. 1 January 1991

Book Section

Nuclear import and export.
Pannek, A. and Stade, K.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1320-1324. ISBN 3-540-44244-8 2006

Proteasomal degradation of misfolded proteins.
Gauss, R. and Neuber, O. and Sommer, T.
In: Chaperones. Topics in Current Genetics ; 16 . Springer, Berlin [u.a.], 185-220. ISBN 3-540-32580-8 2006

Ubiquitination.
Sommer, T. and Dittmar, G.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1964-1968. ISBN 3-540-44244-8 2006

The ubiquitin system in yeast.
Sommer, T.
In: Proteasomes: the World of Regulatory Proteolysis. Molecular Biology Intelligence ; 12 . Landes Bioscience, Georgetown, TX, 204-215. 1 January 2000

High level expression of integral membrane proteins induces proliferation of the endoplasmic reticulum.
Menzel, R. and Kaergel, E. and Wolff, C. and Vogel, F. and Schunck, W.H.
In: Cytochrome P450. Libbey, Paris, 307-310. 1 January 1994

Selective degradation by the ubiquitin system.
Jentsch, S. and Heinlein, R. and Jungmann, J. and Reins, H.A. and Schlenker, S. and Seufert, W. and Sommer, T. and Springer, S.
In: Posttranscriptional control of gene expression. Springer, Heidelberg. 1 January 1993

Ubiquitin-dependent protein degradation.
Jentsch, S. and Hauser, H.P. and Heinlein, R. and Jungmann, J. and Schlenker, S. and Seufert, W. and Sommer, T. and Springer, S.
In: Protein synthesis and targeting in yeast. NATO ASI series : Ser. H, Cell biology ; 71 . Springer, Heidelberg. ISBN 3-540-56521-3 ; 0-387-56521-3 1 January 1993

Ubiquitin-dependent protein degradation.
Jentsch, S. and Seufert, W. and Sommer, T. and Reins, H.A. and Jungmann, J. and Hauser, H.P.
In: DNA replication and the cell cycle. Colloquium der Gesellschaft fuer Biologische Chemie ; 43 . Springer, Berlin. ISBN 3-540-54729-0; 0-387-54729-0 1 January 1992

Thesis

Untersuchungen zur Regulation des Lipidstoffwechsels in Saccharomyces cerevisiae.
Urban, J.
UNSPECIFIED thesis, UNSPECIFIED. 19 October 2001

Review

Protein quality control and elimination of protein waste: the role of the ubiquitin-proteasome system.
Amm, I. and Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1843 (1): 182-196. January 2014

Finding the will and the way of ERAD substrate retrotranslocation.
Hampton, R.Y. and Sommer, T.
Current Opinion in Cell Biology 24 (4): 460-466. August 2012

Protein dislocation from the ER.
Bagola, K. and Mehnert, M. and Jarosch, E. and Sommer, T.
Biochimica et Biophysica Acta - Biomembranes 1808 (3): 925-936. March 2011

Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.
Buchberger, A. and Bukau, B. and Sommer, T.
Molecular Cell 40 (2): 238-252. 22 October 2010

ERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum.
Mehnert, M. and Sommer, T. and Jarosch, E.
BioEssays 32 (10): 905-913. October 2010

The ubiquitylation machinery of the endoplasmic reticulum.
Hirsch, C. and Gauss, R. and Horn, S.C. and Neuber, O. and Sommer, T.
Nature 458 (7237): 453-460. 26 March 2009

Coping with stress: cellular relaxation techniques.
Hirsch, C. and Gauss, R. and Sommer, T.
Trends in Cell Biology 16 (12): 657-663. December 2006

ERAD: the long road to destruction.
Meusser, B. and Hirsch, C. and Jarosch, E. and Sommer, T.
Nature Cell Biology 7 (8): 766-772. August 2005

Endoplasmic reticulum-associated protein degradation - one model fits all?
Hirsch, C. and Jarosch, E. and Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1695 (1-3): 215-223. 1 January 2004

Endoplasmic reticulum-associated protein degradation.
Jarosch, E. and Lenk, U. and Sommer, T.
International Review of Cytology 223 : 39-81. 2003

Protein dislocation from the endoplasmic reticulum - Pulling out the suspect.
Jarosch, E. and Geiss-Friedlander, R. and Meusser, B. and Walter, J. and Sommer, T.
Traffic 3 (8): 530-536. 1 January 2002

Compartment-specific functions of the ubiquitin-proteasome pathway.
Sommer, T. and Jarosch, E. and Lenk, U.
Reviews of Physiology Biochemistry and Pharmacology 142 : 97-160. 2001

Endoplasmic reticulum degradation: reverse protein flow of no return.
Sommer, T. and Wolf, D.H.
FASEB Journal 11 : 1227-1233. 1 January 1997

Genetic analysis of ubiquitin-dependent protein degradation.
Sommer, T. and Seufert, W.
Experientia 48 : 172-178. 15 February 1992

Is the mammary-derived growth inhibitor (MDGI) related 70 kD antigen, identified in nuclei, a nuclear receptor for MDGI or its hydrophobic ligands?
Vogel, F. and Mueller, T. and Grosse, R.
Progress in Histochemistry and Cytochemistry : 159-163. 1 January 1992

In situ localization of cytochrome P-450, the first enzyme involved in aliphatic hydrocarbon degradation in the yeast Candida maltosa.
Vogel, F. and Kaergel, E. and Schunck, W.H.
Progress in Histochemistry and Cytochemistry 23 : 383-389. 1 January 1991

Letter

Stefan Jentsch (1955-2016) Obituary.
Sommer, T. and Hoppe, T. and Rape, M.
Cell 167 (7): 1667-1668. 15 December 2016

Stefan Jentsch (1955-2016) Obituary.
Sommer, T. and Hoppe, T. and Rape, M.
Molecular Cell 64 (6): 1011-1012. 15 December 2016

Varshavsky's contributions.
Baumeister, W. and Bachmair, A. and Chau, V. and Cohen, R. and Coffino, P. and DeMartino, G. and Deshaies, R. and Dohmen, J. and Emr, S. and Finley, D. and Hampton, R. and Hill, C. and Hochstrasser, M. and Huber, R. and Jackson, P. and Jentsch, S. and Johnson, E. and Kwon, Y.T. and Pagano, M. and Pickart, C. and Rechsteiner, M. and Scheffner, M. and Sommer, T. and Tansey, W. and Tyers, M. and Vierstra, R. and Weissman, A. and Wilkinson, K.D. and Wolf, D.
Science 306 (5700): 1290-1292. 1 January 2004

Editorial

Nikolai V. Timofeeff-Ressovsky and the Campus Berlin-Buch.
Sommer, T.
Genetics, Evolution and Radiation : ix-xi. 2016

151 years Berliner Klinische Wochenschrift and the 20th anniversary of the Journal of Molecular Medicine.
Ganten, D. and Semenza, G. and Sommer, T.
Journal of Molecular Medicine 93 (9): 935-936. September 2015

Rsp5/Nedd4 clears cells of heat-damaged proteins.
Sommer, T. and Weber, A. and Jarosch, E.
Nature Cell Biology 16 (12): 1130-1132. 1 December 2014

The ubiquitin-proteasome-system.
Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1843 (1): 1. January 2014

Protein quality control: On IPODs and other JUNQ.
Bagola, K. and Sommer, T.
Current Biology 18 (21): R1019-R1021. 11 November 2008

Lectins in the endoplasmic reticulum: the sweet side of protein quality control.
Sommer, T. and Gauss, R.
Developmental Cell 14 (4): 463-464. 15 April 2008

Pardon me - No access without ubiquitin.
Sommer, T. and Jarosch, E.
Developmental Cell 8 (1): 4-5. 1 January 2005

San1p, checking up on nuclear proteins.
Sommer, T. and Hirsch, C.
Cell 120 (6): 734-736. 1 January 2005

Death gives birth to life: the essential role of the ubiquitin-proteasome system in biology.
Wolf, D.H. and Sommer, T. and Hilt, W.
Biochimica et Biophysica Acta - Molecular Cell Research 1695 (1-3): 1-2. 1 January 2004

BiP binding keeps ATF6 at bay.
Sommer, T. and Jarosch, E.
Developmental Cell 3 (1): 1-2. 11 July 2002

This list was generated on Wed Dec 12 02:18:17 2018 CET.
Open Access
MDC Library