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Research Teams (130)
- Simon, Katja (130)

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Article

Spermidine mitigates immune cell senescence and boosts vaccine responses in healthy older adults -- a pilot study.
Alsaleh, Ghada, Ali, Mohammad ORCID: https://orcid.org/0000-0003-0170-7182, Kayvanjoo, Amir Hossein ORCID: https://orcid.org/0000-0003-1315-8336, Liu, Feng, Moreau, Tanaïs, Bibi, Sagida, Luo, Lin, Govender, Melissa, Carroll, Miles, Hofer, Sebastian J., Tobias, Eisenberg, Magnes, Christoph, Kell, Loren ORCID: https://orcid.org/0000-0003-1322-2027, Chung, Christopher, Deng, Yu, Bhandari, Aneesha, Garner, Lucy ORCID: https://orcid.org/0000-0002-6461-252X, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Chen, Liye, Kronsteiner-Dobramysl, Barbara, Dunachie, Susie, Spiller, Owen B. ORCID: https://orcid.org/0000-0002-9117-6911, Lambe, Teresa, Klenerman, Paul, Jones, Lucy C. and Simon, A. Katharina ORCID: https://orcid.org/0000-0002-4077-7995
Aging Cell 25 (6): e70545. June 2026

Spermidine supplementation and protein restriction protect from organismal and brain aging independently.
Liang, Y.T. ORCID: https://orcid.org/0000-0002-5802-1045, Krivograd, A., Hofer, S.J. ORCID: https://orcid.org/0000-0002-0756-0014, Kollipara, L., Züllig, T., Sickmann, A., Eisenberg, T. and Sigrist, S.J.
Aging 17 (6): 1429-1451. 30 June 2025

Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.
Lyu, Y.X., Fu, Q., Wilczok, D., Ying, K., King, A., Antebi, A., Vojta, A., Stolzing, A., Moskalev, A., Georgievskaya, A., Maier, A.B., Olsen, A., Groth, A., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Brunet, A., Jamil, A., Kulaga, A., Bhatti, A., Yaden, B., Pedersen, B.K., Schumacher, B., Djordjevic, B., Kennedy, B., Chen, C., Huang, C.Y., Correll, C.U., Murphy, C.T., Ewald, C.Y., Chen, D., Valenzano, D.R., Sołdacki, D., Erritzoe, D., Meyer, D., Sinclair, D.A., Chini, E.N., Teeling, E.C., Morgen, E., Verdin, E., Vernet, E., Pinilla, E., Fang, E.F., Bischof, E., Mercken, E.M., Finger, F., Kuipers, F., Pun, F.W., Gyülveszi, G., Civiletto, G., Zmudze, G., Blander, G., Pincus, H.A., McClure, J., Kirkland, J.L., Peyer, J., Justice, J.N., Vijg, J., Gruhn, J.R., McLaughlin, J., Mannick, J., Passos, J., Baur, J.A., Betts-LaCroix, J., Sedivy, J.M., Speakman, J.R., Shlain, J., von Maltzahn, J., Andreasson, K.I., Moody, K., Palikaras, K., Fortney, K., Niedernhofer, L.J., Rasmussen, L.J., Veenhoff, L.M., Melton, L., Ferrucci, L., Quarta, M., Koval, M., Marinova, M., Hamalainen, M., Unfried, M., Ringel, M.S., Filipovic, M., Topors, M., Mitin, N., Roy, N., Pintar, N., Barzilai, N., Binetti, P., Singh, P., Kohlhaas, P., Robbins, P.D., Rubin, P., Fedichev, P.O., Kamya, P., Muñoz-Canoves, P., de Cabo, R., Faragher, R.G.A., Konrad, R., Ripa, R., Mansukhani, R., Büttner, S., Wickström, S.A., Brunemeier, S., Jakimov, S., Luo, S., Rosenzweig-Lipson, S., Tsai, S.Y., Dimmeler, S., Rando, T.A., Peterson, T.R., Woods, T., Wyss-Coray, T., Finkel, T., Strauss, T., Gladyshev, V.N., Longo, V.D., Dwaraka, V.B., Gorbunova, V., Acosta-Rodríguez, V.A., Sorrentino, V., Sebastiano, V., Li, W., Suh, Y., Zhavoronkov, A., Scheibye-Knudsen, M. and Bakula, D.
Aging 16 (20): 12955-12976. 31 October 2024

Next questions in autophagy.
Cuervo, A.M., Elazar, Z., Evans, C., Ge, L., Hansen, M., Jäättelä, M., Liang, J.R.A., Loos, B., Mizushima, N., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Tooze, S., Yoshimori, T. and Nakamura, S.
Nature Cell Biology 26 (5): 661-666. May 2024

Autophagy preserves hematopoietic stem cells by restraining MTORC1-mediated cellular anabolism.
Borsa, M. ORCID: https://orcid.org/0000-0003-1519-2597, Obba, S., Richter, F.C., Zhang, H., Riffelmacher, T., Carrelha, J., Alsaleh, G., Jacobsen, S.E.W. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Autophagy 20 (1): 45-57. January 2024

Autophagy takes it all - autophagy inducers target immune aging.
Zinecker, H. ORCID: https://orcid.org/0000-0002-0257-4273 and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Disease Models & Mechanisms 15 (1): dmm049345. 31 January 2022

EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells.
Roy, S. ORCID: https://orcid.org/0000-0002-0332-4962, Rizvi, Z.A., Clarke, A.J. ORCID: https://orcid.org/0000-0003-2846-7860, Macdonald, F., Pandey, A., Zaiss, D.M.W., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Awasthi, A. ORCID: https://orcid.org/0000-0002-2563-1971
Nature Communications 12 (1): 3182. 1 June 2021

The role and uses of antibodies in COVID-19 infections: a living review.
Scourfield, D.C., Reed, S.G., Quastel, M., Alderson, J., Bart, V.M.T., Teijeira Crespo, A., Jones, R., Pring, E., Richter, F.C. ORCID: https://orcid.org/0000-0002-3415-3449 and Burnell, S.E.A. ORCID: https://orcid.org/0000-0003-3920-6180
Oxford Open Immunology 2 (1): iqab003. 28 January 2021

Regulating T-cell differentiation through the polyamine spermidine.
Carriche, G.M., Almeida, L., Stüve, P., Velasquez, L., Dhillon-LaBrooy, A., Roy, U., Lindenberg, M., Strowig, T., Plaza-Sirvent, C., Schmitz, I., Lochner, M., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Sparwasser, T.
Journal of Allergy and Clinical Immunology 147 (1): 335-348. January 2021

Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses.
Alsaleh, G., Panse, I., Swadling, L., Zhang, H., Richter, F.C., Meyer, A., Lord, J., Barnes, E., Klenerman, P., Green, C. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
eLife 9 : e57950. 15 December 2020

Cortical cells are altered by factors including bone morphogenetic protein released from a placental barrier model under altered oxygenation.
Leinster, V.H.L., Phillips, T.J. ORCID: https://orcid.org/0000-0002-4709-2550, Jones, N., Sanderson, S., Simon, K. ORCID: https://orcid.org/0000-0002-4077-7995, Hanley, J. and Case, C.P.
Neuronal Signaling 4 (1): NS20190148. April 2020

Human liver memory CD8(+) T cells use autophagy for tissue residence.
Swadling, L. ORCID: https://orcid.org/0000-0002-0537-6715, Pallett, L.J., Diniz, M.O., Baker, J.M., Amin, O.E., Stegmann, K.A., Burton, A.R., Schmidt, N.M., Jeffery-Smith, A., Zakeri, N., Suveizdyte, K., Froghi, F., Fusai, G., Rosenberg, W.M., Davidson, B.R., Schurich, A., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Maini, M.K.
Cell Reports 30 (3): 687-698. 21 January 2020

Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence.
Zhang, H., Alsaleh, G., Feltham, J., Sun, Y., Napolitano, G., Riffelmacher, T., Charles, P., Frau, L., Hublitz, P., Yu, Z., Mohammed, S., Ballabio, A., Balabanov, S., Mellor, J. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Molecular Cell 76 (1): 110-125. 3 October 2019

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Cossarizza, A., Chang, H.D., Radbruch, A., Acs, A., Adam, D., Adam-Klages, S., Agace, W.W., Aghaeepour, N., Akdis, M., Allez, M., Almeida, L.N., Alvisi, G., Anderson, G., Andrä, I., Annunziato, F., Anselmo, A., Bacher, P., Baldari, C.T., Bari, S., Barnaba, V., Barros-Martins, J., Battistini, L., Bauer, W., Baumgart, S., Baumgarth, N., Baumjohann, D., Baying, B., Bebawy, M., Becher, B., Beisker, W., Benes, V., Beyaert, R., Blanco, A., Boardman, D.A., Bogdan, C., Borger, J.G., Borsellino, G., Boulais, P.E., Bradford, J.A., Brenner, D., Brinkman, R.R., Brooks, A.E.S., Busch, D.H., Büscher, M., Bushnell, T.P., Calzetti, F., Cameron, G., Cammarata, I., Cao, X., Cardell, S.L., Casola, S., Cassatella, M.A., Cavani, A., Celada, A., Chatenoud, L., Chattopadhyay, P.K., Chow, S., Christakou, E., Čičin-Šain, L., Clerici, M., Colombo, F.S., Cook, L., Cooke, A., Cooper, A.M., Corbett, A.J., Cosma, A., Cosmi, L., Coulie, P.G., Cumano, A., Cvetkovic, L., Dang, V.D., Dang-Heine, C., Davey, M.S., Davies, D., De Biasi, S., Del Zotto, G., Dela Cruz, G.V., Delacher, M., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Di Santo, J.P., Diefenbach, A., Dieli, F., Dolf, A., Dörner, T., Dress, R.J., Dudziak, D., Dustin, M., Dutertre, C.A., Ebner, F., Eckle, S.B.G., Edinger, M., Eede, P., Ehrhardt, G.R.A., Eich, M., Engel, P., Engelhardt, B., Erdei, A., Esser, C., Everts, B., Evrard, M., Falk, C.S., Fehniger, T.A., Felipo-Benavent, M., Ferry, H., Feuerer, M., Filby, A., Filkor, K., Fillatreau, S., Follo, M., Förster, I., Foster, J., Foulds, G.A., Frehse, B., Frenette, P.S., Frischbutter, S., Fritzsche, W., Galbraith, D.W., Gangaev, A., Garbi, N., Gaudilliere, B., Gazzinelli, R.T., Geginat, J., Gerner, W., Gherardin, N.A., Ghoreschi, K., Gibellini, L., Ginhoux, F., Goda, K., Godfrey, D.I., Goettlinger, C., González-Navajas, J.M., Goodyear, C.S., Gori, A., Grogan, J.L., Grummitt, D., Grützkau, A., Haftmann, C., Hahn, J., Hammad, H., Hämmerling, G., Hansmann, L., Hansson, G., Harpur, C.M., Hartmann, S., Hauser, A., Hauser, A.E., Haviland, D.L., Hedley, D., Hernández, D.C., Herrera, G., Herrmann, M., Hess, C., Höfer, T., Hoffmann, P., Hogquist, K., Holland, T., Höllt, T., Holmdahl, R., Hombrink, P., Houston, J.P., Hoyer, B.F., Huang, B., Huang, F.P., Huber, J.E., Huehn, J., Hundemer, M., Hunter, C.A., Hwang, W.Y.K., Iannone, A., Ingelfinger, F., Ivison, S.M., Jäck, H.M., Jani, P.K., Jávega, B., Jonjic, S., Kaiser, T., Kalina, T., Kamradt, T., Kaufmann, S.H.E., Keller, B., Ketelaars, S.L.C., Khalilnezhad, A., Khan, S., Kisielow, J., Klenerman, P., Knopf, J., Koay, H.F., Kobow, K., Kolls, J.K., Kong, W.T., Kopf, M., Korn, T., Kriegsmann, K., Kristyanto, H., Kroneis, T., Krueger, A., Kühne, J., Kukat, C., Kunkel, D., Kunze-Schumacher, H., Kurosaki, T., Kurts, C., Kvistborg, P., Kwok, I., Landry, J., Lantz, O., Lanuti, P., LaRosa, F., Lehuen, A., LeibundGut-Landmann, S., Leipold, M.D., Leung, L.Y.T., Levings, M.K., Lino, A.C., Liotta, F., Litwin, V., Liu, Y., Ljunggren, H.G., Lohoff, M., Lombardi, G., Lopez, L., López-Botet, M., Lovett-Racke, A.E., Lubberts, E., Luche, H., Ludewig, B., Lugli, E., Lunemann, S., Maecker, H.T., Maggi, L., Maguire, O., Mair, Fl., Mair, K.H., Mantovani, A., Manz, R.A., Marshall, A.J., Martínez-Romero, A., Martrus, G., Marventano, I., Maslinski, W., Matarese, G., Mattioli, A.V., Maueröder, C., Mazzoni, A., McCluskey, J., McGrath, M., McGuire, H.M., McInnes, I.B., Mei, H.E., Melchers, F., Melzer, S., Mielenz, D., Miller, S.D., Mills, K.H.G., Minderman, H., Mjösberg, J., Moore, J., Moran, B., Moretta, L., Mosmann, T.R., Müller, S., Multhoff, G., Muñoz, L.E., Münz, C., Nakayama, T., Nasi, M., Neumann, K., Ng, L.G., Niedobitek, A., Nourshargh, S., Núñez, G., O'Connor, J.E., Ochel, A., Oja, A., Ordonez, D., Orfao, A., Orlowski-Oliver, E., Ouyang, W., Oxenius, A., Palankar, R., Panse, I., Pattanapanyasat, K., Paulsen, M., Pavlinic, D., Penter, L., Peterson, P., Peth, C., Petriz, J., Piancone, F., Pickl, W.F., Piconese, S., Pinti, M., Pockley, A.G., Podolska, M.J., Poon, Z., Pracht, K., Prinz, I., Pucillo, C.E.M., Quataert, S.A., Quatrini, L., Quinn, K.M., Radbruch, H., Radstake, T.R.D.J., Rahmig, S., Rahn, H.P. ORCID: https://orcid.org/0000-0002-5233-3937, Rajwa, B., Ravichandran, G., Raz, Y., Rebhahn, J.A., Recktenwald, D., Reimer, D., Reis E Sousa, C., Remmerswaal, E.B.M., Richter, L., Rico, L.G., Riddell, A., Rieger, A.M., Robinson, J.P, Romagnani, C., Rubartelli, A., Ruland, J., Saalmüller, A., Saeys, Y., Saito, T., Sakaguchi, S., Sala-de-Oyanguren, F., Samstag, Y., Sanderson, S., Sandrock, I., Santoni, A., Sanz, R.B., Saresella, M., Sautes-Fridman, C., Sawitzki, B., Schadt, L., Scheffold, A., Scherer, H.U, Schiemann, M., Schildberg, F.A., Schimisky, E., Schlitzer, A., Schlosser, J., Schmid, S., Schmitt, S., Schober, K., Schraivogel, D., Schuh, W., Schüler, T., Schulte, R., Schulz, A.R., Schulz, S.R., Scottá, C., Scott-Algara, D., Sester, D.P., Shankey, T.V., Silva-Santos, B., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Sitnik, K.M., Sozzani, S., Speiser, D.E., Spidlen, J., Stahlberg, A., Stall, A.M., Stanley, N., Stark, R., Stehle, C., Steinmetz, T., Stockinger, H., Takahama, Y., Takeda, K., Tan, L., Tárnok, A., Tiegs, G., Toldi, G., Tornack, J., Traggiai, E., Trebak, M., Tree, T.I.M., Trotter, J., Trowsdale, J., Tsoumakidou, M., Ulrich, H., Urbanczyk, S., van de Veen, W., van den Broek, M., van der Pol, E., Van Gassen, S., Van Isterdael, G., van Lier, R.A.W., Veldhoen, M., Vento-Asturias, S., Vieira, P., Voehringer, D., Volk, H.D., von Borstel, A., von Volkmann, K., Waisman, A., Walker, R.V., Wallace, P.K., Wang, S.A., Wang, X.M., Ward, M.D., Ward-Hartstonge, K.A., Warnatz, K., Warnes, G., Warth, S., Waskow, C., Watson, J.V., Watzl, C., Wegener, L., Weisenburger, T., Wiedemann, A., Wienands, J., Wilharm, A., Wilkinson, R.J., Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X, Wing, J.B., Winkelmann, R., Winkler, T.H., Wirz, O.F., Wong, A., Wurst, P., Yang, J.H.M., Yang, J., Yazdanbakhsh, M., Yu, L., Yue, A., Zhang, H., Zhao, Y., Ziegler, S.M., Zielinski, C., Zimmermann, J. and Zychlinsky, A.
European Journal of Immunology 49 (10): 1457-1973. October 2019

Insights into pancreatic β cell energy metabolism using rodent β cell models.
Morten, K.J., Potter, M., Badder, L., Sivathondan, P., Dragovic, R., Neumann, A., Gavin, J. ORCID: https://orcid.org/0000-0003-1696-3170, Shrestha, R., Reilly, S. ORCID: https://orcid.org/0000-0003-1231-1239, Phadwal, K., Lodge, T.A. ORCID: https://orcid.org/0000-0001-6065-0935, Borzychowski, A., Cookson, S., Mitchell, C., Morovat, A. ORCID: https://orcid.org/0000-0002-5832-7992, Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Uusimaa, J., Hynes, J. and Poulton, J. ORCID: https://orcid.org/0000-0002-2460-5587
Wellcome Open Research 2 : 14. 25 September 2019

A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation.
Breglio, K.F., Amato, R., Eastman, R., Lim, P., Sa, J.M., Guha, R., Ganesan, S., Dorward, D.W., Klumpp-Thomas, C., McKnight, C., Fairhurst, R.M., Roberts, D., Thomas, C. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Malaria Journal 17 (1): 391. 26 October 2018

Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells.
Smith, A.M., Depp, C., Ryan, B.J., Johnston, G.I., Alegre-Abarrategui, J., Evetts, S., Rolinski, M., Baig, F., Ruffmann, C., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Hu, M.T.M. and Wade-Martins, R.
Movement Disorders 33 (10): 1580-1590. October 2018

B1a B cells require autophagy for metabolic homeostasis and self-renewal.
Clarke, A.J. ORCID: https://orcid.org/0000-0003-2846-7860, Riffelmacher, T. ORCID: https://orcid.org/0000-0002-0372-5272, Braas, D., Cornall, R.J. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Journal of Experimental Medicine 215 (2): 399-413. 5 February 2018

In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay.
Sanderson, S.L. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Aging Cell 16 (6): 1234-1243. December 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (first edition).
Cossarizza, A., Chang, H.D., Radbruch, A., Akdis, M., Andrä, I., Annunziato, F., Bacher, P., Barnaba, V., Battistini, L., Bauer, W.M., Baumgart, S., Becher, B., Beisker, W., Berek, C., Blanco, A., Borsellino, G., Boulais, P.E., Brinkman, R.R., Büscher, M., Busch, D.H., Bushnell, T.P., Cao, X., Cavani, A., Chattopadhyay, P.K., Cheng, Q., Chow, S., Clerici, M., Cooke, A., Cosma, A., Cosmi, L., Cumano, A., Dang, V.D., Davies, D., De Biasi, S., Del Zotto, G., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Diefenbach, A., Di Santo, J., Dieli, F., Dolf, A., Donnenberg, V.S., Dörner, T., Ehrhardt, G.R.A., Endl, E., Engel, P., Engelhardt, B., Esser, C., Everts, B., Dreher, A., Falk, C.S., Fehniger, T.A., Filby, A., Fillatreau, S., Follo, M., Förster, I., Foster, J., Foulds, G.A., Frenette, P.S., Galbraith, D., Garbi, N., García-Godoy, M.D., Geginat, J., Ghoreschi, K., Gibellini, L., Goettlinger, C., Goodyear, C.S., Gori, A., Grogan, J., Gross, M., Grützkau, A., Grummitt, D., Hahn, J., Hammer, Q., Hauser, A.E., Haviland, D.L., Hedley, D., Herrera, G., Herrmann, M., Hiepe, F., Holland, T., Hombrink, P., Houston, J.P., Hoyer, B.F., Huang, B., Hunter, C.A., Iannone, A., Jäck, H.M., Jávega, B., Jonjic, S., Juelke, K., Jung, S., Kaiser, T., Kalina, T., Keller, B., Khan, S., Kienhöfer, D., Kroneis, T., Kunkel, D., Kurts, C., Kvistborg, P., Lannigan, J., Lantz, O., Larbi, A., LeibundGut-Landmann, S., Leipold, M.D., Levings, M.K., Litwin, V., Liu, Y., Lohoff, M., Lombardi, G., Lopez, L., Lovett-Racke, A., Lubberts, E., Ludewig, B., Lugli, E., Maecker, H.T., Martrus, G., Matarese, G., Maueröder, C., McGrath, M., McInnes, I., Mei, H.E., Melchers, F., Melzer, S., Mielenz, D., Mills, K., Mirrer, D., Mjösberg, J., Moore, J., Moran, B., Moretta, A., Moretta, L., Mosmann, T.R., Müller, S., Müller, W., Münz, C., Multhoff, G., Munoz, L.E., Murphy, K.M., Nakayama, T., Nasi, M., Neudörfl, C., Nolan, J., Nourshargh, S., O'Connor, J.E., Ouyang, W., Oxenius, A., Palankar, R., Panse, I., Peterson, P., Peth, C., Petriz, J., Philips, D., Pickl, W., Piconese, S., Pinti, M., Pockley, A.G., Podolska, M.J., Pucillo, C., Quataert, S.A., Radstake, T.R.D.J., Rajwa, B., Rebhahn, J.A., Recktenwald, D., Remmerswaal, E.B.M., Rezvani, K., Rico, L.G., Robinson, J.P., Romagnani, C., Rubartelli, A., Ruckert, B., Ruland, J., Sakaguchi, S., Sala-de-Oyanguren, F., Samstag, Y., Sanderson, S., Sawitzki, B., Scheffold, A., Schiemann, M., Schildberg, F., Schimisky, E., Schmid, S.A., Schmitt, S., Schober, K., Schüler, T., Schulz, A.R., Schumacher, T., Scotta, C., Shankey, T.V., Shemer, A., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Spidlen, J., Stall, A.M., Stark, R., Stehle, C., Stein, M., Steinmetz, T., Stockinger, H., Takahama, Y., Tarnok, A., Tian, Z.G., Toldi, G., Tornack, J., Traggiai, E., Trotter, J., Ulrich, H., van der Braber, M., van Lier, R.A.W., Veldhoen, M., Vento-Asturias, S., Vieira, P., Voehringer, D., Volk, H.D., von Volkmann, K., Waisman, A., Walker, R., Ward, M.D., Warnatz, K., Warth, S., Watson, J.V., Watzl, C., Wegener, L., Wiedemann, A., Wienands, J., Willimsky, G., Wing, J., Wurst, P., Yu, L., Yue, A., Zhang, Q., Zhao, Y., Ziegler, S. and Zimmermann, J.
European Journal of Immunology 47 (10): 1584-1797. 11 October 2017

Autophagy-dependent generation of free fatty acids is critical for normal neutrophil differentiation.
Riffelmacher, T., Clarke, A., Richter, F.C., Stranks, A., Pandey, S., Danielli, S., Hublitz, P., Yu, Z., Johnson, E., Schwerd, T., McCullagh, J., Uhlig, H., Jacobsen, S.E.W. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Immunity 47 (3): 466-480.e5. 19 September 2017

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.
Liao, C., Ashley, N., Diot, A., Morten, K., Phadwal, K., Williams, A., Fearnley, I., Rosser, L., Lowndes, J., Fratter, C., Ferguson, D.J.P., Vay, L., Quaghebeur, G., Moroni, I., Bianchi, S., Lamperti, C., Downes, S.M., Sitarz, K.S., Flannery, P.J., Carver, J., Dombi, E., East, D., Laura, M., Reilly, M.M., Mortiboys, H., Prevo, R., Campanella, M., Daniels, M.J., Zeviani, M., Yu-Wai-Man, P., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Votruba, M. and Poulton, J.
Neurology 88 (2): 131-142. 10 January 2017

Exposure to zidovudine adversely affects mitochondrial turnover in primary T cells.
Wallace, Z.R., Sanderson, S., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Dorrell, L.
Antiviral Research 133 : 178-82. September 2016

Autophagy in T and B lymphocytes.
Clarke, A.J. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Autophagy Networks in Inflammation : 171-184. 25 August 2016

Non-canonical autophagy LAPs lupus.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Clarke, A.J.
Cell Death and Differentiation 23 (8): 1267-8. August 2016

The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.
Kabat, A.M., Harrison, O.J., Riffelmacher, T., Moghaddam, A.E., Pearson, C.F., Laing, A., Abeler-Dörner, L., Forman, S.P., Grencis, R.K., Sattentau, Q. ORCID: https://orcid.org/0000-0001-7170-1937, Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Pott, J. and Maloy, K.J.
eLife 5 : e12444. 11 March 2016

Techniques for the detection of autophagy in primary mammalian cells.
Puleston, D., Phadwal, K., Watson, A.S., Soilleux, E.J., Chittaranjan, S., Bortnik, S., Gorski, S.M., Ktistakis, N. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Cold Spring Harbor Protocols 2015 (9): pdb.top070391. 1 September 2015

Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia.
Watson, A.S., Riffelmacher, T., Stranks, A., Williams, O., De Boer, J., Cain, K., MacFarlane, M., McGouran, J., Kessler, B., Khandwala, S., Chowdhury, O., Puleston, D., Phadwal, K., Mortensen, M., Ferguson, D., Soilleux, E., Woll, P., Jacobsen, S.E.W. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Cell Death Discovery 1 : 15008. 17 August 2015

Autophagy controls acquisition of aging features in macrophages.
Stranks, A.J., Hansen, A.L., Panse, I., Mortensen, M., Ferguson, D.J.P., Puleston, D.J., Shenderov, K., Watson, A.S., Veldhoen, M., Phadwal, K., Cerundolo, V. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Journal of Innate Immunity 7 (4): 375-391. June 2015

Autophagy is activated in systemic lupus erythematosus and required for plasmablast development.
Clarke, A.J., Ellinghaus, U., Cortini, A., Stranks, A., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Botto, M. and Vyse, T.J.
Annals of the Rheumatic Diseases 74 (5): 912-20. May 2015

An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease.
Pienaar, I.S., Harrison, I.F., Elson, J.L., Bury, A., Woll, P., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Dexter, D.T.
Brain Structure & Function 220 (1): 479-500. January 2015

Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.
Jabir, M.S., Hopkins, L., Ritchie, N.D., Ullah, I., Bayes, H.K., Li, D., Tourlomousis, P., Lupton, A., Puleston, D., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Bryant, C. and Evans, T.J.
Autophagy 11 (1): 166-182. 2015

Essential role for autophagy during invariant NKT cell development.
Salio, M., Puleston, D.J., Mathan, T.S.M., Shepherd, D., Stranks, A.J., Adamopoulou, E., Veerapen, N., Besra, G.S., Hollander, G.A., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Cerundolo, V.
Proceedings of the National Academy of Sciences of the United States of America 111 (52): E5678-E5687. 30 December 2014

Dual proteolytic pathways govern glycolysis and immune competence.
Lu, W., Zhang, Y., McDonald, D.O., Jing, H., Carroll, B., Robertson, N., Zhang, Q., Griffin, H., Sanderson, S., Lakey, J.H., Morgan, N.V., Reynard, L.N., Zheng, L., Murdock, H.M., Turvey, S.E., Hackett, S.J., Prestidge, T., Hall, J.M., Cant, A.J., Matthews, H.F., Koref, M.F.S., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Korolchuk, V.I., Lenardo, M.J., Hambleton, S. and Su, H.C.
Cell 159 (7): 1578-1590. 18 December 2014

Autophagy is a critical regulator of memory CD8(+) T cell formation.
Puleston, D.J., Zhang, H., Powell, T.J., Lipina, E., Sims, S., Panse, I., Watson, A.S., Cerundolo, V., Townsend, A.R., Klenerman, P. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
eLife 3 : e03706. 11 November 2014

Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions.
Curtis, D.J., Sood, A., Phillips, T.J., Leinster, V.H.L., Nishiguchi, A., Coyle, C., Lacharme-Lora, L., Beaumont, O., Kemp, H., Goodall, R., Cornes, L., Giugliano, M., Barone, R.A., Matsusaki, M., Akashi, M., Tanaka, H.Y., Kano, M., McGarvey, J., Halemani, N.D., Simon, K. ORCID: https://orcid.org/0000-0002-4077-7995, Keehan, R., Ind, W., Masters, T., Grant, S., Athwal, S., Collett, G., Tannetta, D., Sargent, I.L., Scull-Brown, E., Liu, X., Aquilina, K., Cohen, N., Lane, J.D., Thoresen, M., Hanley, J., Randall, A. and Case, C.P.
Experimental Neurology 261 : 386-395. November 2014

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8(+) T cells.
Henson, S.M., Lanna, A., Riddell, N.E., Franzese, O., Macaulay, R., Griffiths, S.J., Puleston, D.J., Watson, A.S., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Tooze, S.A. and Akbar, A.N.
Journal of Clinical Investigation 124 (9): 4004-4016. 2 September 2014

Caspase-1 cleavage of the TLR adaptor TRIF inhibits autophagy and β-interferon production during Pseudomonas aeruginosa infection.
Jabir, M.S., Ritchie, N.D., Li, D., Bayes, H.K., Tourlomousis, P., Puleston, D., Lupton, A., Hopkins, L., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Bryant, C. and Evans, T.J.
Cell Host & Microbe 15 (2): 214-227. 12 February 2014

Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival.
Pike, L.R.G., Singleton, D.C., Buffa, F., Abramczyk, O., Phadwal, K., Li, J.L., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Murray, J.T. and Harris, A.L.
Biochemical Journal 449 (2): 389-400. 15 January 2013

ATF4 orchestrates a program of BH3-only protein expression in severe hypoxia.
Pike, L.R.G., Phadwal, K., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Harris, A.L
Molecular Biology Reports 39 (12): 10811-22. December 2012

Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity.
Lopez-Herrera, G., Tampella, G., Pan-Hammarström, Q., Herholz, P., Trujillo-Vargas, C.M., Phadwal, K., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Moutschen, M., Etzioni, A., Mory, A., Srugo, I., Melamed, D., Hultenby, K., Liu, C., Baronio, M., Vitali, M., Philippet, P., Dideberg, V., Aghamohammadi, A., Rezaei, N., Enright, V., Du, L., Salzer, U., Eibel, H., Pfeifer, D., Veelken, H., Stauss, H., Lougaris, V., Plebani, A., Gertz, E.M., Schäffer, A.A., Hammarström, L. and Grimbacher, B.
American Journal of Human Genetics 90 (6): 986-1001. 8 June 2012

The immune response to melanoma is limited by thymic selection of self-antigens.
Träger, U., Sierro, S., Djordjevic, G., Bouzo, B., Khandwala, S., Meloni, A., Mortensen, M. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
PLoS ONE 7 (4): e35005. 10 April 2012

A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Phadwal, K., Alegre-Abarrategui, J., Watson, A.S., Pike, L., Anbalagan, S., Hammond, E.M., Wade-Martins, R., McMichael, A., Klenerman, P. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Autophagy 8 (4): 677-89. 1 April 2012

Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.
Roberts, N.A., White, A.J., Jenkinson, W.E., Turchinovich, G., Nakamura, K., Withers, D.R., McConnell, F.M., Desanti, G.E., Benezech, C., Parnell, S.M., Cunningham, A.F., Paolino, M., Penninger, J.M., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Nitta, T., Ohigashi, I., Takahama, Y., Caamano, J.H., Hayday, A.C., Lane, P.J.L., Jenkinson, E.J. and Anderson, G.
Immunity 36 (3): 427-37. 23 March 2012

HspB8 mutation causing hereditary distal motor neuropathy impairs lysosomal delivery of autophagosomes.
Kwok, A.S., Phadwal, K., Turner, B.J., Oliver, P.L., Raw, A., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Talbot, K. and Agashe, V.R.
Journal of Neurochemistry 119 (6): 1155-61. December 2011

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness.
Sood, A., Salih, S., Roh, D., Lacharme-Lora, L., Parry, M., Hardiman, B., Keehan, R., Grummer, R., Winterhager, E., Gokhale, P.J., Andrews, P.W., Abbott, C., Forbes, K., Westwood, M., Aplin, J.D., Ingham, E., Papageorgiou, I., Berry, M., Liu, J., Dick, A.D., Garland, R.J., Williams, N., Singh, R., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Lewis, M., Ham, J., Roger, L., Baird, D.M., Crompton, L.A., Caldwell, M.A., Swalwell, H., Birch-Machin, M., Lopez-Castejon, G., Randall, A., Lin, H., Suleiman, M.S., Evans, W.H., Newson, R. and Case, C.P.
Nature Nanotechnology 6 (12): 824-33. December 2011

Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes.
Rasmussen, S.B., Horan, K.A., Holm, C.K., Stranks, A.J., Mettenleiter, T.C., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Jensen, S.B., Rixon, F.J., He, B. and Paludan, S.R.
Journal of Immunology 187 (10): 5268-76. 15 November 2011

Autophagy in the pathogenesis of myelodysplastic syndrome and acute myeloid leukemia.
Watson, A.S., Mortensen, M. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Cell Cycle 10 (11): 1719-25. 1 June 2011

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.
Mortensen, M., Soilleux, E.J., Djordjevic, G., Tripp, R., Lutteropp, M., Sadighi-Akha, E., Stranks, A.J., Glanville, J., Knight, S., Jacobsen, S.E.W., Kranc, K.R. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Journal of Experimental Medicine 208 (3): 455-67. 14 March 2011

Novel role of regulatory T cells in limiting early neutrophil responses in skin.
Richards, H., Williams, A., Jones, E., Hindley, J., Godkin, A., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Gallimore, A.
Immunology 131 (4): 583-92. December 2010

Mitochondrial clearance by autophagy in developing erythrocytes: clearly important, but just how much so?
Mortensen, M., Ferguson, D.J.P. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Cell Cycle 9 (10): 1901-6. 31 May 2010

Nonredundant role of Atg7 in mitochondrial clearance during erythroid development.
Mortensen, M. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Autophagy 6 (3): 423-5. 1 April 2010

Potent adaptive immune responses induced against HIV-1 gp140 and influenza virus HA by a polyanionic carbomer.
Krashias, G., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Wegmann, F., Kok, W.L., Ho, L.P., Stevens, D., Skehel, J., Heeney, J.L., Moghaddam, A.E. and Sattentau, Q.J. ORCID: https://orcid.org/0000-0001-7170-1937
Vaccine 28 (13): 2482-9. 16 March 2010

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo.
Mortensen, M., Ferguson, D.J.P., Edelmann, M., Kessler, B., Morten, K.J., Komatsu, M. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Proceedings of the National Academy of Sciences of the United States of America 107 (2): 832-7. 12 January 2010

Depletion of CD4+CD25+ regulatory T cells enhances natural killer T cell-mediated anti-tumour immunity in a murine mammary breast cancer model.
Hong, H., Gu, Y., Zhang, H., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Chen, X., Wu, C., Xu, X.N. and Jiang, S.
Clinical and Experimental Immunology 159 (1): 93-9. January 2010

Enhanced immune recognition of cryptic glycan markers in human tumors.
Newsom-Davis, T.E., Wang, D., Steinman, L., Chen, P.F.T., Wang, L.X., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Screaton, G.R.
Cancer Research 69 (5): 2018-25. 1 March 2009

BAC-mediated transgenic expression of fluorescent autophagic protein Beclin 1 reveals a role for Beclin 1 in lymphocyte development.
Arsov, I., Li, X., Matthews, G., Coradin, J., Hartmann, B., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Sealfon, S.C. and Yue, Z.
Cell Death and Differentiation 15 (9): 1385-95. September 2008

Generation of tumour-rejecting anti-carbohydrate monoclonal antibodies using melanoma modified with Fas ligand.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Newsom-Davis, T., Frayne, M.E.F., Ch'en, P.F.T., McMichael, A.J. and Screaton, G.R.
International Immunology 20 (4): 525-34. April 2008

Regulatory T cells inhibit Fas ligand-induced innate and adaptive tumour immunity.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Jones, E., Richards, H., Wright, K., Betts, G., Godkin, A., Screaton, G. and Gallimore, A.
European Journal of Immunology 37 (3): 758-67. March 2007

A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouse.
Isaacs, A.M., Oliver, P.L., Jones, E.L., Jeans, A., Potter, A., Hovik, B.H., Nolan, P.M., Vizor, L., Glenister, P., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Gray, I.C., Spurr, N.K., Brown, S.D.M., Hunter, A.J. and Davies, K.E.
Journal of Neuroscience 23 (5): 1631-7. 1 March 2003

Fas ligand breaks tolerance to self-antigens and induces tumor immunity mediated by antibodies.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Gallimore, A., Jones, E., Sawitzki, B., Cerundolo, V. and Screaton, G.R.
Cancer Cell 2 (4): 315-22. October 2002

Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice.
Jones, E., Dahm-Vicker, M., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Green, A., Powrie, F., Cerundolo, V. and Gallimore, A.
Cancer Immunity 2 : 1. February 2002

Tumor necrosis factor-related apoptosis-inducing ligand in T cell development: sensitivity of human thymocytes.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Williams, O., Mongkolsapaya, J., Jin, B., Xu, X.N., Walczak, H. and Screaton, G.R.
Proceedings of the National Academy of Sciences of the United States of America 98 (9): 5158-63. 24 April 2001

The lack of NF-kappa B transactivation and PKC epsilon expression in CD4(+)CD8(+) thymocytes correlates with negative selection.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Auphan, N., Pophillat, M., Boyer, C., Ghosh, S., Rincón, M., Flavell, R.A. and Schmitt-Verhulst, A.M.
Cell Death and Differentiation 7 (12): 1253-62. 1 December 2000

Consequences of intrathymic TCR engagement by partial agonist on selection events and peripheral T cell activation program.
Auphan, N., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Asnagli, H., Phillips, R.J., Rincon, M., Ghosh, S., Flavell, R.A. and Schmitt-Verhulst, A.M.
Journal of Immunology 160 (10): 4810-21. 15 May 1998

Interferon-regulatory factors during development of CD4 and CD8 thymocytes.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Desrois, M. and Schmitt-Verhulst, A.M.
Immunology 91 (3): 340-5. July 1997

Developmental control of antigen-induced thymic transcription factors.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Auphan, N. and Schmitt-Verhulst, A.M.
International Immunology 8 (9): 1421-8. 1 September 1996

Two signaling pathways can lead to Fas ligand expression in CD8+ cytotoxic T lymphocyte clones.
Anel, A., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Auphan, N., Buferne, M., Boyer, C., Golstein, P. and Schmitt-Verhulst, A.M.
European Journal of Immunology 25 (12): 3381-7. December 1995

Divergent T-cell cytokine patterns in inflammatory arthritis.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Seipelt, E. and Sieper, J.
Proceedings of the National Academy of Sciences of the United States of America 91 (18): 8562-6. 30 August 1994

Analysis of cytokine profiles in synovial T cell clones from chlamydial reactive arthritis patients: predominance of the Th1 subset.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Seipelt, E., Wu, P., Wenzel, B., Braun, J. and Sieper, J.
Clinical and Experimental Immunology 94 (1): 122-6. October 1993

In situ localization of HLA class I mRNA in human testis.
Janitz, M., Fiszer, D., Jaruzelska, J., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Biro, A., Sachs, J.A. and Kurpisz, M.
Experimental and Clinical Immunogenetics 10 (4): 202-7. 1993

Tolerance of self induced in thymus organ culture.
Robertson, K., Simon, K. ORCID: https://orcid.org/0000-0002-4077-7995, Schneider, S., Timms, E. and Mitchison, A.
European Journal of Immunology 22 (1): 207-11. January 1992

Purification of recombinant Mycobacterium leprae 65-kilodalton antigen and murine antibody responses to intravenously administered recombinant protein.
Char, S., Colston, M.J., Mitchison, N.A. and Simon, K. ORCID: https://orcid.org/0000-0002-4077-7995
Tropical Medicine and Parasitology 41 (3): 336-8. September 1990

Dominant reduced responsiveness controlled by H-2(Kb)Ab. A new pattern evoked by Thy-1 antigen and F liver antigen.
Mitchison, N.A. and Simon, K. ORCID: https://orcid.org/0000-0002-4077-7995
Immunogenetics 32 (2): 104-9. August 1990

Conference or Workshop Item

The influence of CD25+ cells on the generation of immunity to tumour cell lines in mice.
Jones, E., Golgher, D., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Dahm-Vicker, M., Screaton, G., Elliott, T. and Gallimore, A.
In: Novartis Foundation Symposium 256. 2004

Review

Metabolic control of RNA splicing by polyamines.
Hofer, Sebastian J. ORCID: https://orcid.org/0000-0002-0756-0014, Alsaleh, Ghada ORCID: https://orcid.org/0000-0002-4211-3420 and Simon, Anna Katharina ORCID: https://orcid.org/0000-0002-4077-7995
Trends in Biochemical Sciences 26 June 2026 (In Press)

Adaptive crosstalk between polyamine metabolism, translation, and autophagy sustains energy homeostasis in mammals during starvation: a scoping review.
Karimi, Kayhan ORCID: https://orcid.org/0009-0008-2851-2100, Roberts, Sigrid C. ORCID: https://orcid.org/0000-0002-0964-8554, Carter, Nicola S. ORCID: https://orcid.org/0000-0003-4720-1582, Hofer, Sebastian J. ORCID: https://orcid.org/0000-0002-0756-0014 and Karimi, Reza ORCID: https://orcid.org/0000-0003-3018-8326
Amino Acids 58 (1): 25. 2 April 2026

Dysfunctional mitochondria in ageing T cells: a perspective on mitochondrial quality control mechanisms.
Luo, Lin ORCID: https://orcid.org/0000-0003-2300-5448, Lechuga-Vieco, Ana Victoria ORCID: https://orcid.org/0000-0001-5546-9752, Sattentau, Clara, Borsa, Mariana ORCID: https://orcid.org/0000-0003-1519-2597 and Simon, Anna Katharina ORCID: https://orcid.org/0000-0002-4077-7995
EMBO Reports 26 (18): 4402-4418. 23 September 2025

Understanding and improving vaccine efficacy in older adults.
Hofer, Sebastian J. ORCID: https://orcid.org/0000-0002-0756-0014, Rapp, Simon ORCID: https://orcid.org/0000-0002-5141-0611, Klenerman, Paul and Simon, Anna Katharina ORCID: https://orcid.org/0000-0002-4077-7995
Nature Aging 5 (8): 1455-1470. August 2025

Proteostasis in T cell aging.
Gressler, A.E. ORCID: https://orcid.org/0000-0003-3229-1554, Leng, H., Zinecker, H. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Seminars in Immunology 70 : 101838. November 2023

Autophagy orchestrates the crosstalk between cells and organs.
Piletic, K., Alsaleh, G. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
EMBO Reports 24 (9): e57289. 6 September 2023

The central role of DNA damage in immunosenescence.
Kell, L., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Alsaleh, G. and Cox, L.S.
Frontiers in Aging 4 : 1202152. 3 July 2023

Age-related mechanisms in the context of rheumatic disease.
Alsaleh, G. ORCID: https://orcid.org/0000-0002-4211-3420, Richter, F.C. ORCID: https://orcid.org/0000-0002-3415-3449 and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Nature Reviews Rheumatology 18 (12): 694-710. December 2022

Mechanisms of spermidine-induced autophagy and geroprotection.
Hofer, S.J. ORCID: https://orcid.org/0000-0002-0756-0014, Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Bergmann, M., Eisenberg, T. ORCID: https://orcid.org/0000-0003-3559-1130, Kroemer, G. ORCID: https://orcid.org/0000-0002-9334-4405 and Madeo, F. ORCID: https://orcid.org/0000-0002-5070-1329
Nature Aging 2 (12): 1112-1129. December 2022

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
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ORCID: https://orcid.org/0000-0002-6190-1414, Dauphinee, A.N., Davies, J.S., Dávila, V.A., Davis, R.J., Davis, T., Dayalan Naidu, S., De Amicis, F., De Bosscher, K., De Felice, F., De Franceschi, L., De Leonibus, C., de Mattos Barbosa, M.G., De Meyer, G.R.Y., De Milito, A., De Nunzio, C., De Palma, C., De Santi, M., De Virgilio, C., De Zio, D., Debnath, J., DeBosch, B.J., Decuypere, J.P., Deehan, M.A., Deflorian, G., DeGregori, J., Dehay, B., Del Rio, G., Delaney, J.R., Delbridge, L.M.D., Delorme-Axford, E., Delpino, M.V., Demarchi, F., Dembitz, V., Demers, N.D., Deng, H., Deng, Z., Dengjel, J., Dent, P., Denton, D., DePamphilis, M.L., Der, C.J., Deretic, V., Descoteaux, A., Devis, L., Devkota, S., Devuyst, O., Dewson, G., Dharmasivam, M., Dhiman, R., di Bernardo, D., Di Cristina, M., Di Domenico, F., Di Fazio, P., Di Fonzo, A., Di Guardo, G., Di Guglielmo, G.M., Di Leo, L., Di Malta, C., Di Nardo, A., Di Rienzo, M., Di Sano, F., Diallinas, G., Diao, J., Diaz-Araya, G., Díaz-Laviada, 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Scheuring, D., Schiaffino, M.V., Schiappacassi, M., Schindl, R., Schlattner, U., Schmidt, O., Schmitt, R., Schmidt, S.D., Schmitz, I., Schmukler, E., Schneider, A., Schneider, B.E., Schober, R., Schoijet, A.C., Schott, M.B., Schramm, M., Schröder, B., Schuh, K., Schüller, C., Schulze, R.L., Schürmanns, L., Schwamborn, J.C., Schwarten, M., Scialo, F., Sciarretta, S., Scott, M.J., Scotto, K.W., Scovassi, A.I., Scrima, A., Scrivo, A., Sebastian, D., Sebti, S., Sedej, S., Segatori, L., Segev, N., Seglen, P.O., Seiliez, I., Seki, E., Selleck, S.B., Sellke, F.W., Selsby, J.T., Sendtner, M., Senturk, S., Seranova, E., Sergi, C., Serra-Moreno, R., Sesaki, H., Settembre, C., Setty, S.R.G., Sgarbi, G., Sha, O., Shacka, J.J., Shah, J.A., Shang, D., Shao, C., Shao, F., Sharbati, S., Sharkey, L.M., Sharma, D., Sharma, G., Sharma, K., Sharma, P., Sharma, S., Shen, H.M., Shen, H., Shen, J., Shen, M., Shen, W., Shen, Z., Sheng, R., Sheng, Z., Sheng, Z.H., Shi, J., Shi, X., Shi, Y.H., Shiba-Fukushima, K., Shieh, J.J., Shimada, Y., Shimizu, S., Shimozawa, M., Shintani, T., Shoemaker, C.J., Shojaei, S., Shoji, I., Shravage, B.V., Shridhar, V., Shu, C.W., Shu, H.B., Shui, K., Shukla, A.K., Shutt, T.E., Sica, V., Siddiqui, A., Sierra, A., Sierra-Torre, V., Signorelli, S., Sil, P., Silva, B.J.A., Silva, J.D., Silva-Pavez, E., Silvente-Poirot, S., Simmonds, R.E., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Simon, H.U., Simons, M., Singh, A., Singh, L.P., Singh, R., Singh, S.V., Singh, S.K., Singh, S.B., Singh, S., Singh, S.P., Sinha, D., Sinha, R.A., Sinha, S., Sirko, A., Sirohi, K., Sivridis, E.L., Skendros, P., Skirycz, A., Slaninová, I., Smaili, S.S., Smertenko, A., Smith, M.D., Soenen, S.J., Sohn, E.J., Sok, S.P.M., Solaini, G., Soldati, T., Soleimanpour, S.A., Soler, R.M., Solovchenko, A., Somarelli, J.A., Sonawane, A., Song, F., Song, H.K., Song, J.X., Song, K., Song, Z., Soria, L.R., Sorice, M., Soukas, A.A., Soukup, S.F., Sousa, D., Sousa, N., Spagnuolo, P.A., Spector, S.A., Srinivas Bharath, M.M., St Clair, D., Stagni, V., Staiano, L., Stalnecker, C.A., Stankov, M.V., Stathopulos, P.B., Stefan, K., Stefan, S.M., Stefanis, L., Steffan, J.S., Steinkasserer, A., Stenmark, H., Sterneckert, J., Stevens, C., Stoka, V., Storch, S., Stork, B., Strappazzon, F., Strohecker, A.M., Stupack, D.G., Su, H., Su, L.Yy, Su, L., Suarez-Fontes, A.M., Subauste, C.S., Subbian, S., Subirada, P.V., Sudhandiran, G., Sue, C.M., Sui, X., Summers, C., Sun, G., Sun, J., Sun, K., Sun, M.X., Sun, Q., Sun, Y., Sun, Z., Sunahara, K.K.S., Sundberg, E., Susztak, K., Sutovsky, P., Suzuki, H., Sweeney, G., Symons, J.D., Sze, S.C.W., Szewczyk, N.J., Tabęcka-Łonczynska, A., Tabolacci, C., Tacke, F., Taegtmeyer, H., Tafani, M., Tagaya, M., Tai, H., Tait, S.W.G., Takahashi, Y., Takats, S., Talwar, P., Tam, C., Tam, S.Y., Tampellini, D., Tamura, A., Tan, C.T., Tan, E.K., Tan, Y.Q., Tanaka, M., Tanaka, M., Tang, D., Tang, J., Tang, T.S., Tanida, I., Tao, Z., Taouis, M., Tatenhorst, L., Tavernarakis, N., Taylor, A., Taylor, G.A., Taylor, J.M., Tchetina, E., Tee, A.R., Tegeder, I., Teis, D., Teixeira, N., Teixeira-Clerc, F., Tekirdag, K.A., Tencomnao, T., Tenreiro, S., Tepikin, A.V., Testillano, P.S., Tettamanti, G., Tharaux, P.L., Thedieck, K., Thekkinghat, A.A., Thellung, S., Thinwa, J.W., Thirumalaikumar, V.P., Thomas, S.M., Thomes, P.G., Thorburn, A., Thukral, L., Thum, T., Thumm, M., Tian, L., Tichy, A., Till, A., Timmerman, V., Titorenko, V.I., Todi, S.V., Todorova, K., Toivonen, J.M., Tomaipitinca, L., Tomar, D., Tomas-Zapico, C., Tomić, S., Tong, B.C.K., Tong, C., Tong, X., Tooze, S.A., Torgersen, M.L., Torii, S., Torres-López, L., Torriglia, A., Towers, C.G., Towns, R., Toyokuni, S., Trajkovic, V., Tramontano, D., Tran, Q.G., Travassos, L.H., Trelford, C.B., Tremel, S., Trougakos, I.P., Tsao, B.P., Tschan, M.P., Tse, H.F., Tse, T.F., Tsugawa, H., Tsvetkov, A.S., Tumbarello, D.A., Tumtas, Y., Tuñón, M.J., Turcotte, S., Turk, B., Turk, V., Turner, B.J., Tuxworth, R.I., Tyler, J.K., Tyutereva, E.V., Uchiyama, Y., Ugun-Klusek, A., Uhlig, H.H., Ułamek-Kozioł, M., Ulasov, I.V., Umekawa, M., Ungermann, C., Unno, R., Urbe, S., Uribe-Carretero, E., Üstün, S., Uversky, V.N., Vaccari, T., Vaccaro, M.I., Vahsen, B.F., Vakifahmetoglu-Norberg, H., Valdor, R., Valente, M.J., Valko, A., Vallee, R.B., Valverde, A.M., Van den Berghe, G., van der Veen, S., Van Kaer, L., van Loosdregt, J., van Wijk, S.J.L., Vandenberghe, W., Vanhorebeek, I., Vannier-Santos, M.A., Vannini, N., Vanrell, M.C., Vantaggiato, C., Varano, G., Varela-Nieto, I., Varga, M., Vasconcelos, M.H., Vats, S., Vavvas, D.G., Vega-Naredo, I., Vega-Rubin-de-Celis, S., Velasco, G., Velázquez, A.P., Vellai, T., Vellenga, E., Velotti, F., Verdier, M., Verginis, P., Vergne, I., Verkade, P., Verma, M., Verstreken, P., Vervliet, T., Vervoorts, J., Vessoni, A.T., Victor, V.M., Vidal, M., Vidoni, C., Vieira, O.V., Vierstra, R.D., Viganó, S., Vihinen, H., Vijayan, V., Vila, M., Vilar, M., Villalba, J.M., Villalobo, A., Villarejo-Zori, B., Villarroya, F., Villarroya, J., Vincent, O., Vindis, C., Viret, C., Viscomi, M.T., Visnjic, D., Vitale, I., Vocadlo, D.J., Voitsekhovskaja, O.V., Volonté, C., Volta, M., Vomero, M., Von Haefen, C., Vooijs, M.A., Voos, W., Vucicevic, L., Wade-Martins, R., Waguri, S., Waite, K.A., Wakatsuki, S., Walker, D.W., Walker, M.J., Walker, S.A., Walter, J., Wandosell, F.G., Wang, B., Wang, C.Y., Wang, C., Wang, C., Wang, C., Wang, C.Y., Wang, D., Wang, F., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H., Wang, H., Wang, H.G., Wang, J., Wang, J., Wang, J., Wang, J., Wang, K., Wang, L., Wang, L., Wang, M.H., Wang, M., Wang, N., Wang, P., Wang, P., Wang, P., Wang, P., Wang, Q.J., Wang, Q., Wang, Q.K., Wang, Q.A., Wang, W.T., Wang, W., Wang, X., Wang, X., Wang, Y., Wang, Y., Wang, Y., Wang, Y.Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Z., Wang, Z., Wang, Z., Warnes, G., Warnsmann, V., Watada, H., Watanabe, E., Watchon, M., Wawrzyńska, A., Weaver, T.E., Wegrzyn, G., Wehman, A.M., Wei, H., Wei, L., Wei, T., Wei, Y., Weiergräber, O.H., Weihl, C.C., Weindl, G., Weiskirchen, R., Wells, A., Wen, R.H., Wen, X., Werner, A., Weykopf, B., Wheatley, S.P., Whitton, J.L., Whitworth, A.J., Wiktorska, K., Wildenberg, M.E., Wileman, T., Wilkinson, S., Willbold, D., Williams, B., Williams, R.S.B., Williams, R.L., Williamson, P.R., Wilson, R.A., Winner, B., Winsor, N.J., Witkin, S.S., Wodrich, H., Woehlbier, U., Wollert, T., Wong, E., Wong, J.H., Wong, R.W., Wong, V.K.W., Wong, W.L., Wu, A.G., Wu, C., Wu, J., Wu, J., Wu, K.K., Wu, M., Wu, S.Y., Wu, S., Wu, S.Y., Wu, S., Wu, W.K.K., Wu, X., Wu, X., Wu, Y.W., Wu, Y., Xavier, R.J., Xia, H., Xia, L., Xia, Z., Xiang, G., Xiang, J., Xiang, M., Xiang, W., Xiao, B., Xiao, G., Xiao, H., Xiao, H.T., Xiao, J., Xiao, L., Xiao, S., Xiao, Y., Xie, B., Xie, C.M., Xie, M., Xie, Y., Xie, Z., Xie, Z., Xilouri, M., Xu, C., Xu, E., Xu, H., Xu, J., Xu, J.R., Xu, L., Xu, W.W., Xu, X., Xue, Y., Yakhine-Diop, S.M.S., Yamaguchi, M., Yamaguchi, O., Yamamoto, A., Yamashina, S., Yan, S., Yan, S.J., Yan, Z., Yanagi, Y., Yang, C., Yang, D.S., Yang, H., Yang, H.T., Yang, H., Yang, J.M., Yang, J., Yang, J., Yang, L., Yang, L., Yang, M., Yang, P.M., Yang, Q., Yang, S., Yang, S., Yang, S.F., Yang, W., Yang, W.Y., Yang, X., Yang, X., Yang, Y., Yang, Y., Yao, H., Yao, S., Yao, X., Yao, Y.G., Yao, Y.M., Yasui, T., Yazdankhah, M., Yen, P.M., Yi, C., Yin, X.M., Yin, Y., Yin, Z., Yin, Z., Ying, M., Ying, Z., Yip, C.K., Yiu, S.P.T., Yoo, Y.H., Yoshida, K., Yoshii, S.R., Yoshimori, T., Yousefi, B., Yu, B., Yu, H., Yu, J., Yu, J., Yu, L., Yu, M.L., Yu, S.W., Yu, V.C., Yu, W.H., Yu, Z., Yu, Z., Yuan, J., Yuan, L.Q., Yuan, S., Yuan, S.S.F., Yuan, Y., Yuan, Z., Yue, J., Yue, Z., Yun, J., Yung, R.L., Zacks, D.N., Zaffagnini, G., Zambelli, V.O., Zanella, I., Zang, Q.S., Zanivan, S., Zappavigna, S., Zaragoza, P., Zarbalis, K.S., Zarebkohan, A., Zarrouk, A., Zeitlin, S.O., Zeng, J., Zeng, J.D., Žerovnik, E., Zhan, L., Zhang, B., Zhang, D.D., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H.L., Zhang, J., Zhang, J., Zhang, J.P., Zhang, K.Y.B., Zhang, L.W., Zhang, L., Zhang, L., Zhang, L., Zhang, L., Zhang, M., Zhang, P., Zhang, S., Zhang, W., Zhang, X., Zhang, X.W., Zhang, X., Zhang, X., Zhang, X., Zhang, X., Zhang, X.D., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y.D., Zhang, Y., Zhang, Y.Y., Zhang, Y., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhao, H., Zhao, L., Zhao, S., Zhao, T., Zhao, X.F., Zhao, Y., Zhao, Y., Zhao, Y., Zhao, Y., Zheng, G., Zheng, K., Zheng, L., Zheng, S., Zheng, X.L., Zheng, Y., Zheng, Z.G., Zhivotovsky, B., Zhong, Q., Zhou, A., Zhou, B., Zhou, C., Zhou, G., Zhou, H., Zhou, H., Zhou, H., Zhou, J., Zhou, J., Zhou, J., Zhou, J., Zhou, K., Zhou, R., Zhou, X.J., Zhou, Y., Zhou, Y., Zhou, Y., Zhou, Z.Y., Zhou, Z., Zhu, B., Zhu, C., Zhu, G.Q., Zhu, H., Zhu, H., Zhu, H., Zhu, W.G., Zhu, Y., Zhu, Y., Zhuang, H., Zhuang, X., Zientara-Rytter, K., Zimmermann, C.M., Ziviani, E., Zoladek, T., Zong, W.X., Zorov, D.B., Zorzano, A., Zou, W., Zou, Z., Zou, Z., Zuryn, S., Zwerschke, W., Brand-Saberi, B., Dong, X.C., Kenchappa, C.S., Li, Z., Lin, Y., Oshima, S., Rong, Y., Sluimer, J.C., Stallings, C.L. and Tong, C.K.
Autophagy 17 (1): 1-382. 8 February 2021

Hallmarks and detection techniques of cellular senescence and cellular ageing in immune cells.
Zhou, D., Borsa, M. ORCID: https://orcid.org/0000-0003-1519-2597 and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Aging Cell 20 (2): e13316. 1 February 2021

Autophagy in the renewal, differentiation and homeostasis of immune cells.
Clarke, A.J. ORCID: https://orcid.org/0000-0003-2846-7860 and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Nature Reviews Immunology 19 (3): 170-183. March 2019

Local exchange of metabolites shapes immunity.
Richter, F.C. ORCID: https://orcid.org/0000-0002-3415-3449, Obba, S. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Immunology 155 (3): 309-319. November 2018

Autophagy dictates metabolism and differentiation of inflammatory immune cells.
Riffelmacher, T., Richter, F.C. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Autophagy 14 (2): 199-206. 2018

Mechanistic roles of autophagy in hematopoietic differentiation.
Riffelmacher, T. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
FEBS Journal 284 (7): 1008-1020. April 2017

Autophagy and immune senescence.
Zhang, H., Puleston, D.J. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Trends in Molecular Medicine 22 (8): 671-686. August 2016

Evolution of the immune system in humans from infancy to old age.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Hollander, G.A. and McMichael, A.
Proceedings of the Royal Society of London Series B-Biological Sciences 282 (1821): 20143085. 22 December 2015

Current questions and possible controversies in autophagy.
Lindqvist, L.M., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Baehrecke, E.H.
Cell Death Discovery 1 : 15036. 9 November 2015

New roles for autophagy and spermidine in T cells.
Puleston, D.J. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Microbial Cell 2 (3): 91-93. March 2015

Autophagy in the immune system.
Puleston, D.J. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Immunology 141 (1): 1-8. January 2014

Autophagy in stem cells.
Guan, J.L., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Prescott, M., Menendez, J.A., Liu, F., Wang, F., Wang, C., Wolvetang, E., Vazquez-Martin, A. and Zhang, J.
Autophagy 9 (6): 830-949. June 2013

Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging.
Phadwal, K., Watson, A.S. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Cellular and Molecular Life Sciences 70 (1): 89-103. January 2013

Guidelines for the use and interpretation of assays for monitoring autophagy.
Klionsky, D.J., Abdalla, F.C., Abeliovich, H., Abraham, R.T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Milojkovic, A. ORCID: https://orcid.org/0009-0001-7621-2283 and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Autophagy 8 (4): 445-544. April 2012

Positive and negative influences of regulatory T cells on tumour immunity.
Gallimore, A.M. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Oncogene 27 (45): 5886-93. 6 October 2008

Editorial

Do metabolic fluxes change with age?
Hofer, Sebastian J. ORCID: https://orcid.org/0000-0002-0756-0014, Simon, Anna Katharina ORCID: https://orcid.org/0000-0002-4077-7995 and Madeo, Frank ORCID: https://orcid.org/0000-0002-5070-1329
Trends in Endocrinology and Metabolism 37 (4): 294-296. April 2026

Nourishing the mind: fasting for brain health.
Hofer, S.J. ORCID: https://orcid.org/0000-0002-0756-0014 and Madeo, F. ORCID: https://orcid.org/0000-0002-5070-1329
Cell Metabolism 36 (8): 1635-1637. 6 August 2024

Blocking glycosphingolipid production alters autophagy in osteoclasts and improves myeloma bone disease.
Leng, H. ORCID: https://orcid.org/0000-0002-4023-8588, Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Horwood, N.J. ORCID: https://orcid.org/0000-0002-6344-1677
Autophagy 20 (4): 930-932. April 2024

Beth Levine 1960-2020.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Mizushima, N. ORCID: https://orcid.org/0000-0002-6258-6444
Nature Cell Biology 22 (8): 909-910. August 2020

Fine-tuning stemness.
Borsa, M. ORCID: https://orcid.org/0000-0003-1519-2597 and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Science 369 (6502): 373-374. 24 July 2020

Polyamines reverse immune senescence via the translational control of autophagy.
Zhang, H. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Autophagy 16 (1): 181-182. January 2020

T. rex attacks the lysosome.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Ballabio, A.
Nature Immunology 14 (1): 10-2. January 2013

Gender equality: is it real?
Simon, K. ORCID: https://orcid.org/0000-0002-4077-7995, Athanassakis, I., Powrie, F. and Montoya, M.
European Journal of Immunology 42 (12): 3095-6. December 2012

Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation.
Mortensen, M., Watson, A.S. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Autophagy 7 (9): 1069-70. September 2011

Suicide determines self.
Medema, J.P. and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
Cell Death and Differentiation 9 (4): 364-6. 1 April 2002

Preprint

Mitochondrial heteroplasmy disrupts osteoclast differentiation and bone resorption by impairing respiratory complex I.
Leng, Houfu ORCID: https://orcid.org/0000-0002-4023-8588, Jiang, Jiahao ORCID: https://orcid.org/0009-0009-5712-5289, Gassner, Katja, Midha, Swati, Justo-Méndez, Raquel, Zheng, Jianqing, Hall, Timothy, Luo, Lin ORCID: https://orcid.org/0000-0003-2300-5448, West, Suzanne D., Vincent, Tonia L., Wann, Angus, Patel, Kashyap A., Poulton, Joanna, O'Callaghan, Chris A., Lechuga-Vieco, Ana Victoria ORCID: https://orcid.org/0000-0001-5546-9752 and Simon, Anna Katharina ORCID: https://orcid.org/0000-0002-4077-7995
bioRxiv : 2025.05.02.651799v4. 25 March 2026

Spermidine mitigates immune cell senescence, enhances autophagy, and boosts vaccine responses in healthy older adults.
Alsaleh, Ghada ORCID: https://orcid.org/0000-0002-4211-3420, Ali, Mohammad, Kayvanjoo, Amir ORCID: https://orcid.org/0000-0003-1315-8336, Liu, Feng, Bibi, Sagida, Luo, Lin ORCID: https://orcid.org/0000-0003-2300-5448, Govender, Melissa, Carroll, Miles, Hofer, Sebastian ORCID: https://orcid.org/0000-0002-0756-0014, Eisenberg, Tobias ORCID: https://orcid.org/0000-0003-3559-1130, Magnes, Christoph, Kell, Loren ORCID: https://orcid.org/0000-0003-1322-2027, Chung, Christopher, Deng, Yu, Bhandari, Aneesha, Chen, Liye, Kronsteiner-Dobramysl, Barbara, Dunachie, Susie, Spiller, Owen, Lambe, Teresa, Klenerman, Paul, Jones, Lucy and Simon, Anna Katharina ORCID: https://orcid.org/0000-0002-4077-7995
Research Square : rs.3.rs-5686388. 2 April 2025

Dataset

Gene expression of daughter CD8+ T cells that inherited or not pre-mitotic mitochondria.
Borsa, M. ORCID: https://orcid.org/0000-0003-1519-2597, Kayvanjoo, A.H. ORCID: https://orcid.org/0000-0003-1315-8336 and Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995
[Dataset] 1 December 2025

Adipocyte autophagy-mediated signals in the control of macrophage phenotype during diet-induced obesity.
Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666 and Simon, Katja ORCID: https://orcid.org/0000-0002-4077-7995
[Dataset] 26 September 2025

Dynamic SILAC in TNF-a induced muscle atrophy Part I.
Düren, Ursula ORCID: https://orcid.org/0009-0006-4407-9031
[Dataset] 16 July 2025

Dynamic SILAC in TNF-a induced muscle atrophy Part II.
Duüren, Ursula ORCID: https://orcid.org/0009-0006-4407-9031
[Dataset] 16 July 2025

This list was generated on Mon Jul 13 01:32:08 2026 UTC.