Browse by Research Team

2024

Women in Autophagy: an initiative to promote gender parity in science.
McCabe, M., Boya, P., Chen, R.H., Chu, C.T., Colombo, M.I., Delgui, L., Eskelinen, E.L., Hamasaki, M., Hansen, M., He, C., Jäättelä, M., Kimchi, A., Kraft, C., Kundu, M., Melendez, A., Pattingre, S., Proikas-Cezanne, T., Sebti, S., Simon, A.K., Simonsen, A., Tooze, S.A., Vaccaro, M.I., Wang, X., White, E., Zhao, Y. and Cuervo, A.M.
Nature Cell Biology 26 (12): 2009-2012. December 2024

Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.
Lyu, Y.X., Fu, Q., Wilczok, D., Ying, K., King, A., Antebi, A., Vojta, A., Stolzing, A., Moskalev, A., Georgievskaya, A., Maier, A.B., Olsen, A., Groth, A., Simon, A.K., Brunet, A., Jamil, A., Kulaga, A., Bhatti, A., Yaden, B., Pedersen, B.K., Schumacher, B., Djordjevic, B., Kennedy, B., Chen, C., Huang, C.Y., Correll, C.U., Murphy, C.T., Ewald, C.Y., Chen, D., Valenzano, D.R., Sołdacki, D., Erritzoe, D., Meyer, D., Sinclair, D.A., Chini, E.N., Teeling, E.C., Morgen, E., Verdin, E., Vernet, E., Pinilla, E., Fang, E.F., Bischof, E., Mercken, E.M., Finger, F., Kuipers, F., Pun, F.W., Gyülveszi, G., Civiletto, G., Zmudze, G., Blander, G., Pincus, H.A., McClure, J., Kirkland, J.L., Peyer, J., Justice, J.N., Vijg, J., Gruhn, J.R., McLaughlin, J., Mannick, J., Passos, J., Baur, J.A., Betts-LaCroix, J., Sedivy, J.M., Speakman, J.R., Shlain, J., von Maltzahn, J., Andreasson, K.I., Moody, K., Palikaras, K., Fortney, K., Niedernhofer, L.J., Rasmussen, L.J., Veenhoff, L.M., Melton, L., Ferrucci, L., Quarta, M., Koval, M., Marinova, M., Hamalainen, M., Unfried, M., Ringel, M.S., Filipovic, M., Topors, M., Mitin, N., Roy, N., Pintar, N., Barzilai, N., Binetti, P., Singh, P., Kohlhaas, P., Robbins, P.D., Rubin, P., Fedichev, P.O., Kamya, P., Muñoz-Canoves, P., de Cabo, R., Faragher, R.G.A., Konrad, R., Ripa, R., Mansukhani, R., Büttner, S., Wickström, S.A., Brunemeier, S., Jakimov, S., Luo, S., Rosenzweig-Lipson, S., Tsai, S.Y., Dimmeler, S., Rando, T.A., Peterson, T.R., Woods, T., Wyss-Coray, T., Finkel, T., Strauss, T., Gladyshev, V.N., Longo, V.D., Dwaraka, V.B., Gorbunova, V., Acosta-Rodríguez, V.A., Sorrentino, V., Sebastiano, V., Li, W., Suh, Y., Zhavoronkov, A., Scheibye-Knudsen, M. and Bakula, D.
Aging 16 (20): 12955-12976. 31 October 2024

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling.
Piletic, K., Kayvanjoo, A.H., Richter, F.C., Borsa, M., Lechuga-Vieco, A.V., Popp, O., Grenet, S., Ko, J.K.L., Zec, K., Kyriazi, M., Koneva, L., Sansom, S., Mertins, P., Powrie, F., Alsaleh, G. and Simon, A.K.
bioRxiv : 2024.09.17.613382. 17 September 2024

Nourishing the mind: fasting for brain health.
Hofer, S.J. and Madeo, F.
Cell Metabolism 36 (8): 1635-1637. 6 August 2024

Next questions in autophagy.
Cuervo, A.M., Elazar, Z., Evans, C., Ge, L., Hansen, M., Jäättelä, M., Liang, J.R.A., Loos, B., Mizushima, N., Simon, A.K., Tooze, S., Yoshimori, T. and Nakamura, S.
Nature Cell Biology 26 (5): 661-666. May 2024

Blocking glycosphingolipid production alters autophagy in osteoclasts and improves myeloma bone disease.
Leng, H., Simon, A.K. and Horwood, N.J.
Autophagy 20 (4): 930-932. April 2024

Inheritance of old mitochondria controls early CD8(+) T cell fate commitment and is regulated by autophagy.
Borsa, M., Lechuga-Vieco, A.V., Kayvanjoo, A.H., Yazicioglu, Y., Compeer, E.B., Richter, F.C., Bui, H., Dustin, M.L., Katajisto, P. and Simon, A.K.
bioRxiv : 2024.01.29.577412. 31 January 2024

Autophagy preserves hematopoietic stem cells by restraining MTORC1-mediated cellular anabolism.
Borsa, M., Obba, S., Richter, F.C., Zhang, H., Riffelmacher, T., Carrelha, J., Alsaleh, G., Jacobsen, S.E.W. and Simon, A.K.
Autophagy 20 (1): 45-57. January 2024

2023

Proteostasis in T cell aging.
Gressler, A.E., Leng, H., Zinecker, H. and Simon, A.K.
Seminars in Immunology 70 : 101838. November 2023

Autophagy orchestrates the crosstalk between cells and organs.
Piletic, K., Alsaleh, G. and Simon, A.K.
EMBO Reports 24 (9): e57289. 6 September 2023

The central role of DNA damage in immunosenescence.
Kell, L., Simon, A.K., Alsaleh, G. and Cox, L.S.
Frontiers in Aging 4 : 1202152. 3 July 2023

Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10.
Richter, F.C., Friedrich, M., Kampschulte, N., Piletic, K., Alsaleh, G., Zummach, R., Hecker, J., Pohin, M., Ilott, N., Guschina, I., Wideman, S.K., Johnson, E., Borsa, M., Hahn, P., Morriseau, C., Hammock, B.D., Schipper, H.S., Edwards, C.M, Zechner, R., Siegmund, B., Weidinger, C., Schebb, N.H., Powrie, F. and Simon, A.K.
EMBO Journal 42 (6): e112202. 15 March 2023

2022

Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.
Leng, H., Zhang, H., Li, L., Zhang, S., Wang, Y., Chavda, S.J., Galas-Filipowicz, D., Lou, H., Ersek, A., Morris, E.V., Sezgin, E., Lee, Y.H., Li, Y., Lechuga-Vieco, A.V., Tian, M., Mi, J.Q., Yong, K., Zhong, Q., Edwards, C.M., Simon, A.K. and Horwood, N.J.
Nature Communications 13 (1): 7868. 22 December 2022

Age-related mechanisms in the context of rheumatic disease.
Alsaleh, G., Richter, F.C. and Simon, A.K.
Nature Reviews Rheumatology 18 (12): 694-710. December 2022

Mechanisms of spermidine-induced autophagy and geroprotection.
Hofer, S.J., Simon, A.K., Bergmann, M., Eisenberg, T., Kroemer, G. and Madeo, F.
Nature Aging 2 (12): 1112-1129. December 2022

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation.
Zhou, D., Borsa, M., Puleston, D.J., Zellner, S., Capera, J., Sanderson, S., Schifferer, M., Hester, S.S., Ge, X., Fischer, R., Jostins, L., Behrends, C., Alsaleh, G. and Simon, A.K.
Nature Communications 13 (1): 5174. 2 September 2022

GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao, Y., Du Jiang, P., Chao, B.N., Cagdas, D., Kubo, S., Balasubramaniyam, A., Zhang, Y., Shadur, B., NaserEddin, A., Folio, L.R., Schwarz, B., Bohrnsen, E., Zheng, L., Lynberg, M., Gottlieb, S., Leney-Greene, M.A., Park, A.Y., Tezcan, I., Akdogan, A., Gocmen, R., Onder, S., Rosenberg, A., Soilleux, E.J., Johnson, E., Jackson, P.K., Demeter, J., Chauvin, S.D., Paul, F., Selbach, M., Bulut, H., Clatworthy, M.R., Tuong, Z.K., Zhang, H., Stewart, B.J., Bosio, C.M., Stepensky, P., Clare, S., Ganesan, S., Pascall, J.C., Daumke, O., Butcher, G.W., McMichael, A.J., Simon, A.K. and Lenardo, M.J.
Journal of Experimental Medicine 219 (6): e20201405. 6 June 2022

Heteroplasmy of wild type mitochondrial DNA variants in mice causes metabolic heart disease with pulmonary hypertension and frailty.
Lechuga-Vieco, A.V., Latorre-Pellicer, A., Calvo, E., Torroja, C., Pellico, J., Acín-Pérez, R., García-Gil, M.L., Santos, A., Bagwan, N., Bonzon-Kulichenko, E., Magni, R., Benito, M., Justo-Méndez, R., Simon, A.K., Sánchez-Cabo, F., Vázquez, J., Ruíz-Cabello, J. and Enríquez, J.A.
Circulation 145 (12): 1084-1101. 5 April 2022

B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice.
Lee, M.S.J., Inoue, T., Ise, W., Matsuo-Dapaah, J., Wing, J.B., Temizoz, B., Kobiyama, K., Hayashi, T., Patil, A., Sakaguchi, S., Simon, A.K., Bezbradica, J.S., Nagatoishi, S., Tsumoto, K., Inoue, J.I., Akira, S., Kurosaki, T., Ishii, K.J. and Coban, C.
Journal of Experimental Medicine 219 (2): e20211336. 7 February 2022

Autophagy takes it all - autophagy inducers target immune aging.
Zinecker, H. and Simon, A.K.
Disease Models & Mechanisms 15 (1): dmm049345. 31 January 2022

2021

Autophagy in major human diseases.
Klionsky, D.J., Petroni, G., Amaravadi, R.K., Baehrecke, E.H., Ballabio, A., Boya, P., Bravo-San Pedro, J.M., Cadwell, K., Cecconi, F., Choi, A.M.K., Choi, M.E., Chu, C.T., Codogno, P., Colombo, M.I., Cuervo, A.M., Deretic, V., Dikic, I., Elazar, Z., Eskelinen, E.L., Fimia, G.M., Gewirtz, D.A., Green, D.R., Hansen, M., Jäättelä, M., Johansen, T., Juhász, G., Karantza, V., Kraft, C., Kroemer, G., Ktistakis, N.T., Kumar, S., Lopez-Otin, C., Macleod, K.F., Madeo, F., Martinez, J., Meléndez, A., Mizushima, N., Münz, C., Penninger, J.M., Perera, R.M., Piacentini, M., Reggiori, F., Rubinsztein, D.C., Ryan, K.M., Sadoshima, J., Santambrogio, L., Scorrano, L., Simon, H.U., Simon, A.K., Simonsen, A., Stolz, A., Tavernarakis, N., Tooze, S.A., Yoshimori, T., Yuan, J., Yue, Z., Zhong, Q., Galluzzi, L. and Pietrocola, F.
EMBO Journal 40 (19): e108863. 1 October 2021

Autophagy in healthy aging and disease.
Aman, Y., Schmauck-Medina, T., Hansen, M., Morimoto, R.I., Simon, A.K., Bjedov, I., Palikaras, K., Simonsen, A., Johansen, T., Tavernarakis, N., Rubinsztein, D.C., Partridge, L., Kroemer, G., Labbadia, J. and Fang, E.F.
Nature Aging 1 (8): 634-650. 12 August 2021

EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells.
Roy, S., Rizvi, Z.A., Clarke, A.J., Macdonald, F., Pandey, A., Zaiss, D.M.W., Simon, A.K. and Awasthi, A.
Nature Communications 12 (1): 3182. 1 June 2021

Asymmetric cell division shapes naive and virtual memory T-cell immunity during ageing.
Borsa, M., Barandun, N., Gräbnitz, F., Barnstorf, I., Baumann, N.S., Pallmer, K., Baumann, S., Stark, D., Balaz, M., Oetiker, N., Wagen, F., Wolfrum, C., Simon, A.K., Joller, N., Barral, Y., Spörri, R. and Oxenius, A.
Nature Communications 12 (1): 2715. 11 May 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Klionsky, D.J., Abdel-Aziz, A.K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M.H., Abudu, Y.P., Acevedo-Arozena, A., Adamopoulos, I.E., Adeli, K., Adolph, T.E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B.B., Agnello, M., Agostinis, P., Agrewala, J.N., Agrotis, A., Aguilar, P.V., Ahmad, S.T., Ahmed, Z.M., Ahumada-Castro, U., Aits, S., Aizawa, S., Akkoc, Y., Akoumianaki, T., Akpinar, H.A., Al-Abd, A.M., Al-Akra, L., Al-Gharaibeh, A., Alaoui-Jamali, M.A., Alberti, S., Alcocer-Gómez, E., Alessandri, C., Ali, M., Alim Al-Bari, M.A., Aliwaini, S., Alizadeh, J., Almacellas, E., Almasan, A., Alonso, A., Alonso, G.D., Altan-Bonnet, N., Altieri, D.C., Álvarez, E.M.C., Alves, S., Alves da Costa, C., Alzaharna, M.M., Amadio, M., Amantini, C., Amaral, C., Ambrosio, S., Amer, A.O., Ammanathan, V., An, Z., Andersen, S.U., Andrabi, S.A., Andrade-Silva, M., Andres, A.M., Angelini, S., Ann, D., Anozie, U.C., Ansari, M.Y., Antas, P., Antebi, A., Antón, Z., Anwar, T., Apetoh, L., Apostolova, N., Araki, T., Araki, Y., Arasaki, K., Araújo, W.L., Araya, J., Arden, C., Arévalo, M.A., Arguelles, S., Arias, E., Arikkath, J., Arimoto, H., Ariosa, A.R., Armstrong-James, D., Arnauné-Pelloquin, L., Aroca, A., Arroyo, D.S., Arsov, I., Artero, R., Asaro, D.M.L., Aschner, M., Ashrafizadeh, M., Ashur-Fabian, O., Atanasov, A.G., Au, A.K., Auberger, P., Auner, H.W., Aurelian, L., Autelli, R., Avagliano, L., Ávalos, Y., Aveic, S., Aveleira, C.A., Avin-Wittenberg, T., Aydin, Y., Ayton, S., Ayyadevara, S., Azzopardi, M., Baba, M.u, Backer, J.M., Backues, S.K., Bae, D.H., Bae, O.N., Bae, S.H., Baehrecke, E.H., Baek, A., Baek, S.H., Baek, S.H., Bagetta, G., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X., Bai, Y., Bairagi, N., Baksi, S., Balbi, T., Baldari, C.T., Balduini, W., Ballabio, A., Ballester, M., Balazadeh, S., Balzan, R., Bandopadhyay, R., Banerjee, S., Banerjee, S., Bánréti, A., Bao, Y., Baptista, M.S., Baracca, A., Barbati, C., Bargiela, A., Barilà, D., Barlow, P.G., Barmada, S.J., Barreiro, E., Barreto, G.E., Bartek, J., Bartel, B., Bartolome, A., Barve, G.R., Basagoudanavar, S.H., Bassham, D.C., Bast, R.C., Basu, A., Batoko, H., Batten, I., Baulieu, E.E., Baumgarner, B.L., Bayry, J., Beale, R., Beau, I., Beaumatin, F., Bechara, L.R.G., Beck, G.R., Beers, M.F., Begun, J., Behrends, C., Behrens, G.M.N., Bei, R., Bejarano, E., Bel, S., Behl, C., Belaid, A., Belgareh-Touzé, N., Bellarosa, C., Belleudi, F., Belló Pérez, M., Bello-Morales, R., Beltran, J.S.O., Beltran, S., Benbrook, D.M., Bendorius, M., Benitez, B.A., Benito-Cuesta, I., Bensalem, J., Berchtold, M.W., Berezowska, S., Bergamaschi, D., Bergami, M., Bergmann, A., Berliocchi, L., Berlioz-Torrent, C., Bernard, A., Berthoux, L., Besirli, C.G., Besteiro, S., Betin, V.M., Beyaert, R., Bezbradica, J.S., Bhaskar, K., Bhatia-Kissova, I., Bhattacharya, R., Bhattacharya, S., Bhattacharyya, S., Bhuiyan, M.S., Bhutia, S.K., Bi, L., Bi, X., Biden, T.J., Bijian, K., Billes, V.A., Binart, N., Bincoletto, C., Birgisdottir, A.B., Bjorkoy, G., Blanco, G., Blas-Garcia, A., Blasiak, J., Blomgran, R., Blomgren, K., Blum, J.S., Boada-Romero, E., Boban, M., Boesze-Battaglia, K., Boeuf, P., Boland, B., Bomont, P., Bonaldo, P., Bonam, S.R., Bonfili, L., Bonifacino, J.S., Boone, B.A., Bootman, M.D., Bordi, M., Borner, C., Bornhauser, B.C., Borthakur, G., Bosch, J., Bose, S., Botana, L.M., Botas, J., Boulanger, C.M., Boulton, M.E., Bourdenx, M., Bourgeois, B., Bourke, N.M., Bousquet, G., Boya, P., Bozhkov, P.V., Bozi, L.H.M., Bozkurt, T.O., Brackney, D.E., Brandts, C.H., Braun, R.J., Braus, G.H., Bravo-Sagua, R., Bravo-San Pedro, J.M., Brest, P., Bringer, M.A., Briones-Herrera, A., Broaddus, V.C., Brodersen, P., Brodsky, J.L., Brody, S.L., Bronson, P.G., Bronstein, J.M., Brown, C.N., Brown, R.E., Brum, P.C., Brumell, J.H., Brunetti-Pierri, N., Bruno, D., Bryson-Richardson, R.J., Bucci, C., Buchrieser, C., Bueno, M., Buitrago-Molina, L.E., Buraschi, S., Buch, S., Buchan, J.R., Buckingham, E.M., Budak, H., Budini, M., Bultynck, G., Burada, F., Burgoyne, J.R., Burón, M.I., Bustos, V., Büttner, S., Butturini, E., Byrd, A., Cabas, I., Cabrera-Benitez, S., Cadwell, K., Cai, J., Cai, L., Cai, Q., Cairó, M., Calbet, J.A., Caldwell, G.A., Caldwell, K.A., Call, J.A., Calvani, R., Calvo, A.C., Calvo-Rubio Barrera, M., Camara, N.O., Camonis, J.H., Camougrand, N., Campanella, M., Campbell, E.M., Campbell-Valois, F.X., Campello, S., Campesi, I., Campos, J.C., Camuzard, O., Cancino, J., Candido de Almeida, D., Canesi, L., Caniggia, I., Canonico, B., Cantí, C., Cao, B., Caraglia, M., Caramés, B., Carchman, E.H., Cardenal-Muñoz, E., Cardenas, C., Cardenas, L., Cardoso, S.M., Carew, J.S., Carle, G.F., Carleton, G., Carloni, S., Carmona-Gutierrez, D., Carneiro, L.A., Carnevali, O., Carosi, J.M., Carra, S., Carrier, A., Carrier, L., Carroll, B., Carter, A.B., Carvalho, A.N., Casanova, M., Casas, C., Casas, J., Cassioli, C., Castillo, E.F., Castillo, K., Castillo-Lluva, S., Castoldi, F., Castori, M., Castro, A.F., Castro-Caldas, M., Castro-Hernandez, J., Castro-Obregon, S., Catz, S.D., Cavadas, C., Cavaliere, F., Cavallini, G., Cavinato, M., Cayuela, M.L., Cebollada Rica, P., Cecarini, V., Cecconi, F., Cechowska-Pasko, M., Cenci, S., Ceperuelo-Mallafré, V., Cerqueira, J.J., Cerutti, J.M., Cervia, D., Cetintas, V.B., Cetrullo, S., Chae, H.J., Chagin, A.S., Chai, C.Y., Chakrabarti, G., Chakrabarti, O., Chakraborty, T., Chakraborty, T., Chami, M., Chamilos, G., Chan, D.W., Chan, E.Y.W., Chan, E.D., Chan, H.Y.E., Chan, H.H., Chan, H., Chan, M.T.V., Chan, Y.S., Chandra, P.K., Chang, C.P., Chang, C., Chang, H.C., Chang, K., Chao, J., Chapman, T., Charlet-Berguerand, N., Chatterjee, S., Chaube, S.K., Chaudhary, A., Chauhan, S., Chaum, E., Checler, F., Cheetham, M.E., Chen, C.S., Chen, G.C., Chen, J.F., Chen, L.L., Chen, L., Chen, L., Chen, M., Chen, M.K., Chen, N., Chen, Q., Chen, R.H., Chen, S., Chen, W., Chen, W., Chen, X.M., Chen, X.W., Chen, X., Chen, Y., Chen, Y.G., Chen, Y., Chen, Y., Chen, Y.J., Chen, Y.Q., Chen, Z.S., Chen, Z., Chen, Z.H., Chen, Z.J., Chen, Z., Cheng, H., Cheng, J., Cheng, S.Y., Cheng, W., Cheng, X., Cheng, X.T., Cheng, Y., Cheng, Z., Chen, Z., Cheong, H., Cheong, J.K., Chernyak, B.V., Cherry, S., Cheung, C.F.R., Cheung, C.H.A., Cheung, K.H., Chevet, E., Chi, R.J., Chiang, A.K.S., Chiaradonna, F., Chiarelli, R., Chiariello, M., Chica, N., Chiocca, S., Chiong, M., Chiou, S.H., Chiramel, A.I., Chiurchiù, V., Cho, D.H., Choe, S.K., Choi, A.M.K., Choi, M.E., Choudhury, K.R., Chow, N.S., Chu, C.T., Chua, J.P., Chua, J.J.E., Chung, H., Chung, K.P., Chung, S., Chung, S.H., Chung, Y.L., Cianfanelli, V., Ciechomska, I.A., Cifuentes, M., Cinque, L., Cirak, S., Cirone, M., Clague, M.J., Clarke, R., Clementi, E., Coccia, E.M., Codogno, P., Cohen, E., Cohen, M.M, Colasanti, T., Colasuonno, F., Colbert, R.A., Colell, A., Čolić, M., Coll, N.S., Collins, M.O., Colombo, M.I., Colón-Ramos, D.A., Combaret, L., Comincini, S., Cominetti, M.R., Consiglio, A., Conte, A., Conti, F., Contu, V.R., Cookson, M.R., Coombs, K.M., Coppens, I., Corasaniti, M.T., Corkery, D.P., Cordes, N., Cortese, K., Costa, M.D.C., Costantino, S., Costelli, P., Coto-Montes, A., Crack, P.J., Crespo, J.L., Criollo, A., Crippa, V., Cristofani, R., Csizmadia, T., Cuadrado, A., Cui, B., Cui, J., Cui, Y., Cui, Y., Culetto, E., Cumino, A.C., Cybulsky, A.V., Czaja, M.J., Czuczwar, S.J., D'Adamo, S., D'Amelio, M., D'Arcangelo, D., D'Lugos, A.C., D'Orazi, G., da Silva, J.A., Dafsari, H.S., Dagda, R.K., Dagdas, Y., Daglia, M., Dai, X., Dai, Y., Dai, Y., Dal Col, J., Dalhaimer, P., Dalla Valle, L., Dallenga, T., Dalmasso, G., Damme, M., Dando, I., Dantuma, N.P., Darling, A.L., Das, H., Dasarathy, S., Dasari, S.K., Dash, S., Daumke, O., Dauphinee, A.N., Davies, J.S., Dávila, V.A., Davis, R.J., Davis, T., Dayalan Naidu, S., De Amicis, F., De Bosscher, K., De Felice, F., De Franceschi, L., De Leonibus, C., de Mattos Barbosa, M.G., De Meyer, G.R.Y., De Milito, A., De Nunzio, C., De Palma, C., De Santi, M., De Virgilio, C., De Zio, D., Debnath, J., DeBosch, B.J., Decuypere, J.P., Deehan, M.A., Deflorian, G., DeGregori, J., Dehay, B., Del Rio, G., Delaney, J.R., Delbridge, L.M.D., Delorme-Axford, E., Delpino, M.V., Demarchi, F., Dembitz, V., Demers, N.D., Deng, H., Deng, Z., Dengjel, J., Dent, P., Denton, D., DePamphilis, M.L., Der, C.J., Deretic, V., Descoteaux, A., Devis, L., Devkota, S., Devuyst, O., Dewson, G., Dharmasivam, M., Dhiman, R., di Bernardo, D., Di Cristina, M., Di Domenico, F., Di Fazio, P., Di Fonzo, A., Di Guardo, G., Di Guglielmo, G.M., Di Leo, L., Di Malta, C., Di Nardo, A., Di Rienzo, M., Di Sano, F., Diallinas, G., Diao, J., Diaz-Araya, G., Díaz-Laviada, I., Dickinson, J.M., Diederich, M., Dieudé, M., Dikic, I., Ding, S., Ding, W.X., Dini, L., Dinić, J., Dinic, M., Dinkova-Kostova, A.T., Dionne, M.S., Distler, J.H.W., Diwan, A., Dixon, I.M.C., Djavaheri-Mergny, M., Dobrinski, I., Dobrovinskaya, O., Dobrowolski, R., Dobson, R.C.J., Đokić, J., Dokmeci Emre, S., Donadelli, M., Dong, B., Dong, X., Dong, Z., Dorn Ii, G.W., Dotsch, V., Dou, H., Dou, J., Dowaidar, M., Dridi, S., Drucker, L., Du, A., Du, C., Du, G., Du, H.N., Du, L.L., du Toit, A., Duan, S.B., Duan, X., Duarte, S.P., Dubrovska, A., Dunlop, E.A., Dupont, N., Durán, R.V., Dwarakanath, B.S., Dyshlovoy, S.A., Ebrahimi-Fakhari, D., Eckhart, L., Edelstein, C.L., Efferth, T., Eftekharpour, E., Eichinger, L., Eid, N., Eisenberg, T., Eissa, N.T., Eissa, S., Ejarque, M., El Andaloussi, A., El-Hage, N., El-Naggar, S., Eleuteri, A.M., El-Shafey, E.S., Elgendy, M., Eliopoulos, A.G., Elizalde, M.M., Elks, P.M., Elsasser, H.P., Elsherbiny, E.S., Emerling, B.M., Emre, N.C.T., Eng, C.H., Engedal, N., Engelbrecht, A.M., Engelsen, A.S.T., Enserink, J.M., Escalante, R., Esclatine, A., Escobar-Henriques, M., Eskelinen, E.L., Espert, L., Eusebio, M.O., Fabrias, G., Fabrizi, C., Facchiano, A., Facchiano, F., Fadeel, B., Fader, C., Faesen, A.C., Fairlie, W.D., Falcó, A., Falkenburger, B.H., Fan, D., Fan, J., Fan, Y., Fang, E.F., Fang, Y., Fang, Y., Fanto, M., Farfel-Becker, T., Faure, M., Fazeli, G., Fedele, A.O., Feldman, A.M., Feng, D., Feng, J., Feng, L., Feng, Y., Feng, Y., Feng, W., Fenz Araujo, T., Ferguson, T.A., Fernández, A.F., Fernandez-Checa, J.C., Fernández-Veledo, S., Fernie, A.R., Ferrante, A.W., Ferraresi, A., Ferrari, M.F., Ferreira, J.C.B., Ferro-Novick, S., Figueras, A., Filadi, R., Filigheddu, N., Filippi-Chiela, E., Filomeni, G., Fimia, G.M., Fineschi, V., Finetti, F., Finkbeiner, S., Fisher, E.A., Fisher, P.B., Flamigni, F., Fliesler, S.J., Flo, T.H., Florance, I., Florey, O., Florio, T., Fodor, E., Follo, C., Fon, E.A., Forlino, A., Fornai, F., Fortini, P., Fracassi, A., Fraldi, A., Franco, B., Franco, R., Franconi, F., Frankel, L.B., Friedman, S.L., Fröhlich, L.F., Frühbeck, G., Fuentes, J.M., Fujiki, Y., Fujita, N., Fujiwara, Y., Fukuda, M., Fulda, S., Furic, L., Furuya, N., Fusco, C., Gack, M.U., Gaffke, L., Galadari, S., Galasso, A., Galindo, M.F., Gallolu Kankanamalage, S., Galluzzi, L., Galy, V., Gammoh, N., Gan, B., Ganley, I.G., Gao, F., Gao, H., Gao, M., Gao, P., Gao, S.J., Gao, W., Gao, X., Garcera, A., Garcia, M.N., Garcia, V.E., García-Del Portillo, F., Garcia-Escudero, V., Garcia-Garcia, A., Garcia-Macia, M., García-Moreno, D., Garcia-Ruiz, C., García-Sanz, P., Garg, A.D., Gargini, R., Garofalo, T., Garry, R.F., Gassen, N.C., Gatica, D., Ge, L., Ge, W., Geiss-Friedlander, R., Gelfi, C., Genschik, P., Gentle, I.E., Gerbino, V., Gerhardt, C., Germain, K., Germain, M., Gewirtz, D.A., Ghasemipour Afshar, E., Ghavami, S., Ghigo, A., Ghosh, M., Giamas, G., Giampietri, C., Giatromanolaki, A., Gibson, G.E., Gibson, S.B., Ginet, V., Giniger, E., Giorgi, C., Girao, H., Girardin, S.E., Giridharan, M., Giuliano, S., Giulivi, C., Giuriato, S., Giustiniani, J., Gluschko, A., Goder, V., Goginashvili, A., Golab, J., Goldstone, D.C., Golebiewska, A., Gomes, L.R., Gomez, R., Gómez-Sánchez, R., Gomez-Puerto, M.C., Gomez-Sintes, R., Gong, Q., Goni, F.M., González-Gallego, J., Gonzalez-Hernandez, T., Gonzalez-Polo, R.A., Gonzalez-Reyes, J.A., González-Rodríguez, P., Goping, I.S., Gorbatyuk, M.S., Gorbunov, N.V., Görgülü, K., Gorojod, R.M., Gorski, S.M., Goruppi, S., Gotor, C., Gottlieb, R.A., Gozes, I., Gozuacik, D., Graef, M., Gräler, M.H., Granatiero, V., Grasso, D., Gray, J.P., Green, D.R., Greenhough, A., Gregory, S.L., Griffin, E.F., Grinstaff, M.W., Gros, F., Grose, C., Gross, A.S., Gruber, F., Grumati, P., Grune, T., Gu, X., Guan, J.L., Guardia, C.M., Guda, K., Guerra, F., Guerri, C., Guha, P., Guillén, C., Gujar, S., Gukovskaya, A., Gukovsky, I., Gunst, J., Günther, A., Guntur, A.R., Guo, C., Guo, C., Guo, H., Guo, L.W., Guo, M., Gupta, P., Gupta, S.K., Gupta, S., Gupta, V.B., Gupta, V., Gustafsson, A.B., Gutterman, D.D., H B, R., Haapasalo, A., Haber, J.E., Hać, A., Hadano, S., Hafrén, A.J., Haidar, M., Hall, B.S., Halldén, G., Hamacher-Brady, A., Hamann, A., Hamasaki, M., Han, W., Hansen, M., Hanson, P.I., Hao, Z., Harada, M., Harhaji-Trajkovic, L., Hariharan, N., Haroon, N., Harris, J., Hasegawa, T., Hasima Nagoor, N., Haspel, J.A., Haucke, V., Hawkins, W.D., Hay, B.A., Haynes, C.M., Hayrabedyan, S.B., Hays, T.S., He, C., He, Q., He, R.R., He, Y.W., He, Y.Y., Heakal, Y., Heberle, A.M., Hejtmancik, J.F., Helgason, G.V., Henkel, V., Herb, M., Hergovich, A., Herman-Antosiewicz, A., Hernández, A., Hernandez, C., Hernandez-Diaz, S., Hernandez-Gea, V., Herpin, A., Herreros, J., Hervás, J.H., Hesselson, D., Hetz, C., Heussler, V.T., Higuchi, Y., Hilfiker, S., Hill, J.A., Hlavacek, W.S., Ho, E.A., Ho, I.H.T., Ho, P.W.L., Ho, S.L., Ho, W.Y., Hobbs, G.A., Hochstrasser, M., Hoet, P.H.M., Hofius, D., Hofman, P., Höhn, A., Holmberg, C.I., Hombrebueno, J.R., Yi-Ren Hong, C.W.H., Hooper, L.V., Hoppe, T., Horos, R., Hoshida, Y., Hsin, I.L., Hsu, H.Y., Hu, B., Hu, D., Hu, L.F., Hu, M.C., Hu, R., Hu, W., Hu, Y.C., Hu, Z.W., Hua, F., Hua, J., Hua, Y., Huan, C., Huang, C., Huang, C., Huang, C., Huang, C., Huang, H., Huang, K., Huang, M.L.H., Huang, R., Huang, S., Huang, T., Huang, X., Huang, Y.J., Huber, T.B., Hubert, V., Hubner, C.A., Hughes, S.M., Hughes, W.E., Humbert, M., Hummer, G., Hurley, J.H., Hussain, S., Hussain, S., Hussey, P.J., Hutabarat, M., Hwang, H.Y., Hwang, S., Ieni, A., Ikeda, F., Imagawa, Y., Imai, Y., Imbriano, C., Imoto, M., Inman, D.M., Inoki, K., Iovanna, J., Iozzo, R.V., Ippolito, G., Irazoqui, J.E., Iribarren, P., Ishaq, M., Ishikawa, M., Ishimwe, N., Isidoro, C., Ismail, N., Issazadeh-Navikas, S., Itakura, E., Ito, D., Ivankovic, D., Ivanova, S., Iyer, A.K.V., Izquierdo, J.M., Izumi, M., Jäättelä, M., Jabir, M.S., Jackson, W.T., Jacobo-Herrera, N., Jacomin, A.C., Jacquin, E., Jadiya, P., Jaeschke, H., Jagannath, C., Jakobi, A.J., Jakobsson, J., Janji, B., Jansen-Dürr, P., Jansson, P.J., Jantsch, J., Januszewski, S., Jassey, A., Jean, S., Jeltsch-David, H., Jendelova, P., Jenny, A., Jensen, T.E., Jessen, N., Jewell, J.L., Ji, J., Jia, L., Jia, R., Jiang, L., Jiang, Q., Jiang, R., Jiang, T., Jiang, X., Jiang, Y., Jimenez-Sanchez, M., Jin, E.J., Jin, F., Jin, H., Jin, L., Jin, L., Jin, M., Jin, S., Jo, E.K., Joffre, C., Johansen, T., Johnson, G.V.W., Johnston, S.A., Jokitalo, E., Jolly, M.K., Joosten, L.A.B., Jordan, J., Joseph, B., Ju, D., Ju, J.S., Ju, J., Juárez, E., Judith, D., Juhász, G., Jun, Y., Jung, C.H., Jung, S.C., Jung, Y.K., Jungbluth, H., Jungverdorben, J., Just, S., Kaarniranta, K., Kaasik, A., Kabuta, T., Kaganovich, D., Kahana, A., Kain, R., Kajimura, S., Kalamvoki, M., Kalia, M., Kalinowski, D.S., Kaludercic, N., Kalvari, I., Kaminska, J., Kaminskyy, V.O., Kanamori, H., Kanasaki, K., Kang, C., Kang, R., Kang, S.S., Kaniyappan, S., Kanki, T., Kanneganti, T.D., Kanthasamy, A.G., Kanthasamy, A., Kantorow, M., Kapuy, O., Karamouzis, M.V., Karim, M.D.R., Karmakar, P., Katare, R.G., Kato, M., Kaufmann, S.H.E., Kauppinen, A., Kaushal, G.P., Kaushik, S., Kawasaki, K., Kazan, K., Ke, P.Y., Keating, D.J., Keber, U., Kehrl, J.H., Keller, K.E., Keller, C.W., Kemper, J.K., Kenific, C.M., Kepp, O., Kermorgant, S., Kern, A., Ketteler, R., Keulers, T.G., Khalfin, B., Khalil, H., Khambu, B., Khan, S.Y., Khandelwal, V.K.M., Khandia, R., Kho, W., Khobrekar, N.V., Khuansuwan, S., Khundadze, M., Killackey, S.A., Kim, D., Kim, D.R., Kim, D.H., Kim, D.E., Kim, E.Y., Kim, E.K., Kim, H.R., Kim, H.S., Kim, H.R., Kim, J.H., Kim, J.K., Kim, J.H., Kim, J., Kim, J.H., Kim, K.I.I., Kim, P.K., Kim, S.J., Kimball, S.R., Kimchi, A., Kimmelman, A.C., Kimura, T., King, M.A., Kinghorn, K.J., Kinsey, C.G., Kirkin, V., Kirshenbaum, L.A., Kiselev, S.L., Kishi, S., Kitamoto, K., Kitaoka, Y., Kitazato, K., Kitsis, R.N., Kittler, J.T., Kjaerulff, O., Klein, P.S., Klopstock, T., Klucken, J., Knævelsrud, H., Knorr, R.L., Ko, B.C.B., Ko, F., Ko, J.L., Kobayashi, H., Kobayashi, S., Koch, I., Koch, J.C., Koenig, U., Kögel, D., Koh, Y.H., Koike, M., Kohlwein, S.D., Kocaturk, N.M., Komatsu, M., König, J., Kono, T., Kopp, B.T., Korcsmaros, T., Korkmaz, G., Korolchuk, V.I., Korsnes, M.S., Koskela, A., Kota, J., Kotake, Y., Kotler, M.L., Kou, Y., Koukourakis, M.I., Koustas, E., Kovacs, A.L., Kovács, T., Koya, D., Kozako, T., Kraft, C., Krainc, D., Krämer, H., Krasnodembskaya, A.D., Kretz-Remy, C., Kroemer, G., Ktistakis, N.T., Kuchitsu, K., Kuenen, S., Kuerschner, L., Kukar, T., Kumar, A., Kumar, A., Kumar, D., Kumar, D., Kumar, S., Kume, S., Kumsta, C., Kundu, C.N., Kundu, M., Kunnumakkara, A.B., Kurgan, L., Kutateladze, T.G., Kutlu, O., Kwak, S.A., Kwon, H.J., Kwon, T.K., Kwon, Y.T., Kyrmizi, I., La Spada, A., Labonté, P., Ladoire, S., Laface, I., Lafont, F., Lagace, D.C., Lahiri, V., Lai, Z., Laird, A.S., Lakkaraju, A., Lamark, T., Lan, S.H., Landajuela, A., Lane, D.J.R., Lane, J.D., Lang, C.H., Lange, C., Langel, Ü., Langer, R., Lapaquette, P., Laporte, J., LaRusso, N.F., Lastres-Becker, I., Lau, W.C.Y., Laurie, G.W., Lavandero, S., Law, B.Y.K., Law, H.K.W., Layfield, R., Le, W., Le Stunff, H., Leary, A.Y., Lebrun, J.J., Leck, L.Y.W., Leduc-Gaudet, J.P., Lee, C., Lee, C.P., Lee, D.H., Lee, E.B., Lee, E.F., Lee, G.M., Lee, H.J., Lee, H.K., Lee, J.M., Lee, J.S., Lee, J.A., Lee, J.Y., Lee, J.H., Lee, M., Lee, M.G., Lee, M.J., Lee, M.S., Lee, S.Y., Lee, S.J., Lee, S.Y., Lee, S.B., Lee, W.H., Lee, Y.R., Lee, Y.H., Lee, Y., Lefebvre, C., Legouis, R., Lei, Y.L., Lei, Y., Leikin, S., Leitinger, G., Lemus, L., Leng, S., Lenoir, O., Lenz, G., Lenz, H.J., Lenzi, P., León, Y., Leopoldino, A.M., Leschczyk, C., Leskelä, S., Letellier, E., Leung, C.T., Leung, P.S., Leventhal, J.S., Levine, B., Lewis, P.A., Ley, K., Li, B., Li, D.Q., Li, J., Li, J., Li, J., Li, K., Li, L., Li, M., Li, M., Li, M., Li, M., Li, M., Li, P.L., Li, M.Q., Li, Q., Li, S., Li, T., Li, W., Li, W., Li, X., Li, Y.P., Li, Y., Li, Z., Li, Z., Li, Z., Lian, J., Liang, C., Liang, Q., Liang, W., Liang, Y., Liang, Y.T., Liao, G., Liao, L., Liao, M., Liao, Y.F., Librizzi, M., Lie, P.P.Y., Lilly, M.A., Lim, H.J., Lima, T.R.R., Limana, F., Lin, C., Lin, C.W., Lin, D.S., Lin, F.C., Lin, J.D., Lin, K.M., Lin, K.H., Lin, L.T., Lin, P.H., Lin, Q., Lin, S., Lin, S.J., Lin, W., Lin, X., Lin, Y.X., Lin, Y.S., Linden, R., Lindner, P., Ling, S.C., Lingor, P., Linnemann, A.K., Liou, Y.C., Lipinski, M.M., Lipovšek, S., Lira, V.A., Lisiak, N., Liton, P.B., Liu, C., Liu, C.H., Liu, C.F., Liu, C.H., Liu, F., Liu, H., Liu, H.S., Liu, H.F., Liu, H., Liu, J., Liu, J., Liu, J., Liu, L., Liu, L., Liu, M., Liu, Q., Liu, W., Liu, W., Liu, X.H., Liu, X., Liu, X., Liu, X., Liu, X., Liu, Y., Liu, Y., Liu, Y., Liu, Y., Liu, Y., Livingston, J.A., Lizard, G., Lizcano, J.M., Ljubojevic-Holzer, S., LLeonart, M.E., Llobet-Navàs, D., Llorente, A., Lo, C.H., Lobato-Márquez, D., Long, Q., Long, Y.C., Loos, B., Loos, J.A., López, M.G., López-Doménech, G., López-Guerrero, J.A., López-Jiménez, A.T., López-Pérez, O., López-Valero, I., Lorenowicz, M.J., Lorente, M., Lorincz, P., Lossi, L., Lotersztajn, S., Lovat, P.E., Lovell, J.F., Lovy, A., Lőw, P., Lu, G., Lu, H., Lu, J.H., Lu, J.J., Lu, M., Lu, S., Luciani, A., Lucocq, J.M., Ludovico, P., Luftig, M.A., Luhr, M., Luis-Ravelo, D., Lum, J.J., Luna-Dulcey, L., Lund, A.H., Lund, V.K., Lünemann, J.D., Lüningschrör, P., Luo, H., Luo, R., Luo, S., Luo, Z., Luparello, C., Lüscher, B., Luu, L., Lyakhovich, A., Lyamzaev, K.G., Lystad, A.H., Lytvynchuk, L., Ma, A.C., Ma, C., Ma, M., Ma, N.F., Ma, Q.H., Ma, X., Ma, Y., Ma, Z., MacDougald, O.A., Macian, F., MacIntosh, G.C., MacKeigan, J.P., Macleod, K.F., Maday, S., Madeo, F., Madesh, M., Madl, T., Madrigal-Matute, J., Maeda, A., Maejima, Y., Magarinos, M., Mahavadi, P., Maiani, E., Maiese, K., Maiti, P., Maiuri, M.C., Majello, B., Major, M.B., Makareeva, E., Malik, F., Mallilankaraman, K., Malorni, W., Maloyan, A., Mammadova, N., Man, G.C.W., Manai, F., Mancias, J.D., Mandelkow, E.M., Mandell, M.A., Manfredi, A.A., Manjili, M.H., Manjithaya, R., Manque, P., Manshian, B.B., Manzano, R., Manzoni, C., Mao, K., Marchese, C., Marchetti, S., Marconi, A.M., Marcucci, F., Mardente, S., Mareninova, O.A., Margeta, M., Mari, M., Marinelli, S., Marinelli, O., Mariño, G., Mariotto, S., Marshall, R.S., Marten, M.R., Martens, S., Martin, A.P.J., Martin, K.R., Martin, S., Martin, S., Martín-Segura, A., Martín-Acebes, M.A., Martin-Burriel, I., Martin-Rincon, M., Martin-Sanz, P., Martina, J.A., Martinet, W., Martinez, A., Martinez, A., Martinez, J., Martinez Velazquez, M., Martinez-Lopez, N., Martinez-Vicente, M., Martins, D.O., Martins, J.O., Martins, W.K., Martins-Marques, T., Marzetti, E., Masaldan, S., Masclaux-Daubresse, C., Mashek, D.G., Massa, V., Massieu, L., Masson, G.R., Masuelli, L., Masyuk, A.I., Masyuk, T.V., Matarrese, P., Matheu, A., Matoba, S., Matsuzaki, S., Mattar, P., Matte, A., Mattoscio, D., Mauriz, J.L., Mauthe, M., Mauvezin, C., Maverakis, E., Maycotte, P., Mayer, J., Mazzoccoli, G., Mazzoni, C., Mazzulli, J.R., McCarty, N., McDonald, C., McGill, M.R., McKenna, S.L., McLaughlin, B.A., McLoughlin, F., McNiven, M.A., McWilliams, T.G., Mechta-Grigoriou, F., Medeiros, T.C., Medina, D.L., Megeney, L.Y., Megyeri, K., Mehrpour, M., Mehta, J.L., Meijer, A.J., Meijer, A.H., Mejlvang, J., Meléndez, A., Melk, A., Memisoglu, G., Mendes, A.F., Meng, D., Meng, F., Meng, T., Menna-Barreto, R., Menon, M.B., Mercer, C., Mercier, A.E., Mergny, J.L., Merighi, A., Merkley, S.D., Merla, G., Meske, V., Mestre, A.C., Metur, S.P., Meyer, C., Meyer, H., Mi, W., Mialet-Perez, J., Miao, J., Micale, L., Miki, Y., Milan, E., Milczarek, M., Miller, D.L., Miller, S.I., Miller, S., Millward, S.W., Milosevic, I., Minina, E.A., Mirzaei, H., Mirzaei, H.R., Mirzaei, M., Mishra, A., Mishra, N., Mishra, P.K., Misirkic Marjanovic, M., Misasi, R., Misra, A., Misso, G., Mitchell, C., Mitou, G., Miura, T., Miyamoto, S., Miyazaki, M., Miyazaki, M., Miyazaki, T., Miyazawa, K., Mizushima, N., Mogensen, T.H., Mograbi, B., Mohammadinejad, R., Mohamud, Y., Mohanty, A., Mohapatra, S., Möhlmann, T., Mohmmed, A., Moles, A., Moley, K.H., Molinari, M., Mollace, V., Møller, A.B., Mollereau, B., Mollinedo, F., Montagna, C., Monteiro, M.J., Montella, A., Montes, L.R., Montico, B., Mony, V.K., Monzio Compagnoni, G., Moore, M.N., Moosavi, M.A., Mora, A.L., Mora, M., Morales-Alamo, D., Moratalla, R., Moreira, P.I., Morelli, E., Moreno, S., Moreno-Blas, D., Moresi, V., Morga, B., Morgan, A.H., Morin, F., Morishita, H., Moritz, O.L., Moriyama, M., Moriyasu, Y., Morleo, M., Morselli, E., Moruno-Manchon, J.F., Moscat, J., Mostowy, S., Motori, E., Moura, A.F., Moustaid-Moussa, N., Mrakovcic, M., Muciño-Hernández, G., Mukherjee, A., Mukhopadhyay, S., Mulcahy Levy, J.M., Mulero, V., Muller, S., Münch, C., Munjal, A., Munoz-Canoves, P., Muñoz-Galdeano, T., Münz, C., Murakawa, T., Muratori, C., Murphy, B.M., Murphy, J.P., Murthy, A., Myöhänen, T.T., Mysorekar, I.U., Mytych, J., Nabavi, S.M., Nabissi, M., Nagy, P., Nah, J., Nahimana, A., Nakagawa, I., Nakamura, K., Nakatogawa, H., Nandi, S.S., Nanjundan, M., Nanni, M., Napolitano, G., Nardacci, R., Narita, M., Nassif, M., Nathan, I., Natsumeda, M., Naude, R.J., Naumann, C., Naveiras, O., Navid, F., Nawrocki, S.T., Nazarko, T.Y., Nazio, F., Negoita, F., Neill, T., Neisch, A.L., Neri, L.M., Netea, M.G., Neubert, P., Neufeld, T.P., Neumann, D., Neutzner, A., Newton, P.T., Ney, P.A., Nezis, I.P., Ng, C.C.W., Ng, T.B., Nguyen, H.T.T., Nguyen, L.T., Ni, H.M., Ní Cheallaigh, C., Ni, Z., Nicolao, M.C., Nicoli, F., Nieto-Diaz, M., Nilsson, P., Ning, S., Niranjan, R., Nishimune, H., Niso-Santano, M., Nixon, R.A., Nobili, A., Nobrega, C., Noda, T., Nogueira-Recalde, U., Nolan, T.M., Nombela, I., Novak, I., Novoa, B., Nozawa, T., Nukina, N., Nussbaum-Krammer, C., Nylandsted, J., O'Donovan, T.R., O'Leary, S.M., O'Rourke, E.J., O'Sullivan, M.P., O'Sullivan, T.E., Oddo, S., Oehme, I., Ogawa, M., Ogier-Denis, E., Ogmundsdottir, M.H., Ogretmen, B., Oh, G.T., Oh, S.H., Oh, Y.J., Ohama, T., Ohashi, Y., Ohmuraya, M., Oikonomou, V., Ojha, R., Okamoto, K., Okazawa, H., Oku, M., Oliván, S., Oliveira, J.M.A., Ollmann, M., Olzmann, J.A., Omari, S., Omary, M.B., Önal, G., Ondrej, M., Ong, S.B., Ong, S.G., Onnis, A., Orellana, J.A., Orellana-Muñoz, S., Ortega-Villaizan, M.D.M., Ortiz-Gonzalez, X.R., Ortona, E., Osiewacz, H.D., Osman, A.H.K., Osta, R., Otegui, M.S., Otsu, K., Ott, C., Ottobrini, L., Ou, J.H.J., Outeiro, T.F., Oynebraten, I., Ozturk, M., Pagès, G., Pahari, S., Pajares, M., Pajvani, U.B., Pal, R., Paladino, S., Pallet, N., Palmieri, M., Palmisano, G., Palumbo, C., Pampaloni, F., Pan, L., Pan, Q., Pan, W:, Pan, X., Panasyuk, G., Pandey, R., Pandey, U.B., Pandya, V., Paneni, F., Pang, S.Y., Panzarini, E., Papademetrio, D.L., Papaleo, E., Papinski, D., Papp, D., Park, E.C., Park, H.T., Park, J.M., Park, J.I., Park, J.T., Park, J., Park, S.C., Park, S.Y., Parola, A.H., Parys, J.B., Pasquier, A., Pasquier, B., Passos, J.F., Pastore, N., Patel, H.H., Patschan, D., Pattingre, S., Pedraza-Alva, G., Pedraza-Chaverri, J., Pedrozo, Z., Pei, G., Pei, J., Peled-Zehavi, H., Pellegrini, J.M., Pelletier, J., Peñalva, M.A., Peng, D., Peng, Y., Penna, F., Pennuto, M., Pentimalli, F., Pereira, C.M.F., Pereira, G.J.S., Pereira, L.C., Pereira de Almeida, L., Perera, N.D., Pérez-Lara, A., Perez-Oliva, A.B., Pérez-Pérez, M.E., Periyasamy, P., Perl, A., Perrotta, C., Perrotta, I., Pestell, R.G., Petersen, M., Petrache, I., Petrovski, G., Pfirrmann, T., Pfister, A.S., Philips, J.A., Pi, H., Picca, A., Pickrell, A.M., Picot, S., Pierantoni, G.M., Pierdominici, M., Pierre, P., Pierrefite-Carle, V., Pierzynowska, K., Pietrocola, F., Pietruczuk, M., Pignata, C., Pimentel-Muiños, F.X., Pinar, M., Pinheiro, R.O., Pinkas-Kramarski, R., Pinton, P., Pircs, K., Piya, S., Pizzo, P., Plantinga, T.S., Platta, H.W., Plaza-Zabala, A., Plomann, M., Plotnikov, E.Y., Plun-Favreau, H., Pluta, R., Pocock, R., Pöggeler, S., Pohl, C., Poirot, M., Poletti, A., Ponpuak, M., Popelka, H., Popova, B., Porta, H., Porte Alcon, S., Portilla-Fernandez, E., Post, M., Potts, M.B., Poulton, J., Powers, T., Prahlad, V., Prajsnar, T.K., Praticò, D., Prencipe, R., Priault, M., Proikas-Cezanne, T., Promponas, V.J., Proud, C.G., Puertollano, R., Puglielli, L., Pulinilkunnil, T., Puri, D., Puri, R., Puyal, J., Qi, X., Qi, Y., Qian, W., Qiang, L., Qiu, Y., Quadrilatero, J., Quarleri, J., Raben, N., Rabinowich, H., Ragona, D., Ragusa, M.J., Rahimi, N., Rahmati, M., Raia, V., Raimundo, N., Rajasekaran, N.S., Ramachandra Rao, S., Rami, A., Ramírez-Pardo, I., Ramsden, D.B., Randow, F., Rangarajan, P.N., Ranieri, D., Rao, H., Rao, L., Rao, R., Rathore, S., Ratnayaka, J.A., Ratovitski, E.A., Ravanan, P., Ravegnini, G., Ray, S.K., Razani, B., Rebecca, V., Reggiori, F., Régnier-Vigouroux, A., Reichert, A.S., Reigada, D., Reiling, J.H., Rein, T., Reipert, S., Rekha, R.S., Ren, H., Ren, J., Ren, W., Renault, T., Renga, G., Reue, K., Rewitz, K., Ribeiro de Andrade Ramos, B., Riazuddin, S.A., Ribeiro-Rodrigues, T.M., Ricci, J.E., Ricci, R., Riccio, V., Richardson, D.R., Rikihisa, Y., Risbud, M.V., Risueño, R.M., Ritis, K., Rizza, S., Rizzuto, R., Roberts, H.C., Roberts, L.D., Robinson, K.J., Roccheri, M.C., Rocchi, S., Rodney, G.G., Rodrigues, T., Rodrigues Silva, V.R., Rodriguez, A., Rodriguez-Barrueco, R., Rodriguez-Henche, N., Rodriguez-Rocha, H., Roelofs, J., Rogers, R.S., Rogov, V.V., Rojo, A.I., Rolka, K., Romanello, V., Romani, L., Romano, A., Romano, P.S., Romeo-Guitart, D., Romero, L.C., Romero, M., Roney, J.C., Rongo, C., Roperto, S., Rosenfeldt, M.T., Rosenstiel, P., Rosenwald, A.G., Roth, K.A., Roth, L., Roth, S., Rouschop, K.M.A., Roussel, B.D., Roux, S., Rovere-Querini, P., Roy, A., Rozieres, A., Ruano, D., Rubinsztein, D.C., Rubtsova, M.P., Ruckdeschel, K., Ruckenstuhl, C., Rudolf, E., Rudolf, R., Ruggieri, A., Ruparelia, A.A., Rusmini, P., Russell, R.R., Russo, G.L., Russo, M., Russo, R., Ryabaya, O.O., Ryan, K.M., Ryu, K.Y., Sabater-Arcis, M., Sachdev, U., Sacher, M., Sachse, C., Sadhu, A., Sadoshima, J., Safren, N., Saftig, P., Sagona, A.P., Sahay, G., Sahebkar, A., Sahin, M., Sahin, O., Sahni, S., Saito, N., Saito, S., Saito, T., Sakai, R., Sakai, Y., Sakamaki, J.I., Saksela, K., Salazar, G., Salazar-Degracia, A., Salekdeh, G.H., Saluja, A.K., Sampaio-Marques, B., Sanchez, M.C., Sanchez-Alcazar, J.A., Sanchez-Vera, V., Sancho-Shimizu, V., Sanderson, J.T., Sandri, M., Santaguida, S., Santambrogio, L., Santana, M.M., Santoni, G., Sanz, A., Sanz, P., Saran, S., Sardiello, M., Sargeant, T.J., Sarin, A., Sarkar, C., Sarkar, S., Sarrias, M.R., Sarkar, S., Sarmah, D.T., Sarparanta, J., Sathyanarayan, A., Sathyanarayanan, R., Scaglione, K.M., Scatozza, F., Schaefer, L., Schafer, Z.T., Schaible, U.E., Schapira, A.H.V., Scharl, M., Schatzl, H.M., Schein, C.H., Scheper, W., Scheuring, D., Schiaffino, M.V., Schiappacassi, M., Schindl, R., Schlattner, U., Schmidt, O., Schmitt, R., Schmidt, S.D., Schmitz, I., Schmukler, E., Schneider, A., Schneider, B.E., Schober, R., Schoijet, A.C., Schott, M.B., Schramm, M., Schröder, B., Schuh, K., Schüller, C., Schulze, R.L., Schürmanns, L., Schwamborn, J.C., Schwarten, M., Scialo, F., Sciarretta, S., Scott, M.J., Scotto, K.W., Scovassi, A.I., Scrima, A., Scrivo, A., Sebastian, D., Sebti, S., Sedej, S., Segatori, L., Segev, N., Seglen, P.O., Seiliez, I., Seki, E., Selleck, S.B., Sellke, F.W., Selsby, J.T., Sendtner, M., Senturk, S., Seranova, E., Sergi, C., Serra-Moreno, R., Sesaki, H., Settembre, C., Setty, S.R.G., Sgarbi, G., Sha, O., Shacka, J.J., Shah, J.A., Shang, D., Shao, C., Shao, F., Sharbati, S., Sharkey, L.M., Sharma, D., Sharma, G., Sharma, K., Sharma, P., Sharma, S., Shen, H.M., Shen, H., Shen, J., Shen, M., Shen, W., Shen, Z., Sheng, R., Sheng, Z., Sheng, Z.H., Shi, J., Shi, X., Shi, Y.H., Shiba-Fukushima, K., Shieh, J.J., Shimada, Y., Shimizu, S., Shimozawa, M., Shintani, T., Shoemaker, C.J., Shojaei, S., Shoji, I., Shravage, B.V., Shridhar, V., Shu, C.W., Shu, H.B., Shui, K., Shukla, A.K., Shutt, T.E., Sica, V., Siddiqui, A., Sierra, A., Sierra-Torre, V., Signorelli, S., Sil, P., Silva, B.J.A., Silva, J.D., Silva-Pavez, E., Silvente-Poirot, S., Simmonds, R.E., Simon, A.K., Simon, H.U., Simons, M., Singh, A., Singh, L.P., Singh, R., Singh, S.V., Singh, S.K., Singh, S.B., Singh, S., Singh, S.P., Sinha, D., Sinha, R.A., Sinha, S., Sirko, A., Sirohi, K., Sivridis, E.L., Skendros, P., Skirycz, A., Slaninová, I., Smaili, S.S., Smertenko, A., Smith, M.D., Soenen, S.J., Sohn, E.J., Sok, S.P.M., Solaini, G., Soldati, T., Soleimanpour, S.A., Soler, R.M., Solovchenko, A., Somarelli, J.A., Sonawane, A., Song, F., Song, H.K., Song, J.X., Song, K., Song, Z., Soria, L.R., Sorice, M., Soukas, A.A., Soukup, S.F., Sousa, D., Sousa, N., Spagnuolo, P.A., Spector, S.A., Srinivas Bharath, M.M., St Clair, D., Stagni, V., Staiano, L., Stalnecker, C.A., Stankov, M.V., Stathopulos, P.B., Stefan, K., Stefan, S.M., Stefanis, L., Steffan, J.S., Steinkasserer, A., Stenmark, H., Sterneckert, J., Stevens, C., Stoka, V., Storch, S., Stork, B., Strappazzon, F., Strohecker, A.M., Stupack, D.G., Su, H., Su, L.Yy, Su, L., Suarez-Fontes, A.M., Subauste, C.S., Subbian, S., Subirada, P.V., Sudhandiran, G., Sue, C.M., Sui, X., Summers, C., Sun, G., Sun, J., Sun, K., Sun, M.X., Sun, Q., Sun, Y., Sun, Z., Sunahara, K.K.S., Sundberg, E., Susztak, K., Sutovsky, P., Suzuki, H., Sweeney, G., Symons, J.D., Sze, S.C.W., Szewczyk, N.J., Tabęcka-Łonczynska, A., Tabolacci, C., Tacke, F., Taegtmeyer, H., Tafani, M., Tagaya, M., Tai, H., Tait, S.W.G., Takahashi, Y., Takats, S., Talwar, P., Tam, C., Tam, S.Y., Tampellini, D., Tamura, A., Tan, C.T., Tan, E.K., Tan, Y.Q., Tanaka, M., Tanaka, M., Tang, D., Tang, J., Tang, T.S., Tanida, I., Tao, Z., Taouis, M., Tatenhorst, L., Tavernarakis, N., Taylor, A., Taylor, G.A., Taylor, J.M., Tchetina, E., Tee, A.R., Tegeder, I., Teis, D., Teixeira, N., Teixeira-Clerc, F., Tekirdag, K.A., Tencomnao, T., Tenreiro, S., Tepikin, A.V., Testillano, P.S., Tettamanti, G., Tharaux, P.L., Thedieck, K., Thekkinghat, A.A., Thellung, S., Thinwa, J.W., Thirumalaikumar, V.P., Thomas, S.M., Thomes, P.G., Thorburn, A., Thukral, L., Thum, T., Thumm, M., Tian, L., Tichy, A., Till, A., Timmerman, V., Titorenko, V.I., Todi, S.V., Todorova, K., Toivonen, J.M., Tomaipitinca, L., Tomar, D., Tomas-Zapico, C., Tomić, S., Tong, B.C.K., Tong, C., Tong, X., Tooze, S.A., Torgersen, M.L., Torii, S., Torres-López, L., Torriglia, A., Towers, C.G., Towns, R., Toyokuni, S., Trajkovic, V., Tramontano, D., Tran, Q.G., Travassos, L.H., Trelford, C.B., Tremel, S., Trougakos, I.P., Tsao, B.P., Tschan, M.P., Tse, H.F., Tse, T.F., Tsugawa, H., Tsvetkov, A.S., Tumbarello, D.A., Tumtas, Y., Tuñón, M.J., Turcotte, S., Turk, B., Turk, V., Turner, B.J., Tuxworth, R.I., Tyler, J.K., Tyutereva, E.V., Uchiyama, Y., Ugun-Klusek, A., Uhlig, H.H., Ułamek-Kozioł, M., Ulasov, I.V., Umekawa, M., Ungermann, C., Unno, R., Urbe, S., Uribe-Carretero, E., Üstün, S., Uversky, V.N., Vaccari, T., Vaccaro, M.I., Vahsen, B.F., Vakifahmetoglu-Norberg, H., Valdor, R., Valente, M.J., Valko, A., Vallee, R.B., Valverde, A.M., Van den Berghe, G., van der Veen, S., Van Kaer, L., van Loosdregt, J., van Wijk, S.J.L., Vandenberghe, W., Vanhorebeek, I., Vannier-Santos, M.A., Vannini, N., Vanrell, M.C., Vantaggiato, C., Varano, G., Varela-Nieto, I., Varga, M., Vasconcelos, M.H., Vats, S., Vavvas, D.G., Vega-Naredo, I., Vega-Rubin-de-Celis, S., Velasco, G., Velázquez, A.P., Vellai, T., Vellenga, E., Velotti, F., Verdier, M., Verginis, P., Vergne, I., Verkade, P., Verma, M., Verstreken, P., Vervliet, T., Vervoorts, J., Vessoni, A.T., Victor, V.M., Vidal, M., Vidoni, C., Vieira, O.V., Vierstra, R.D., Viganó, S., Vihinen, H., Vijayan, V., Vila, M., Vilar, M., Villalba, J.M., Villalobo, A., Villarejo-Zori, B., Villarroya, F., Villarroya, J., Vincent, O., Vindis, C., Viret, C., Viscomi, M.T., Visnjic, D., Vitale, I., Vocadlo, D.J., Voitsekhovskaja, O.V., Volonté, C., Volta, M., Vomero, M., Von Haefen, C., Vooijs, M.A., Voos, W., Vucicevic, L., Wade-Martins, R., Waguri, S., Waite, K.A., Wakatsuki, S., Walker, D.W., Walker, M.J., Walker, S.A., Walter, J., Wandosell, F.G., Wang, B., Wang, C.Y., Wang, C., Wang, C., Wang, C., Wang, C.Y., Wang, D., Wang, F., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H., Wang, H., Wang, H.G., Wang, J., Wang, J., Wang, J., Wang, J., Wang, K., Wang, L., Wang, L., Wang, M.H., Wang, M., Wang, N., Wang, P., Wang, P., Wang, P., Wang, P., Wang, Q.J., Wang, Q., Wang, Q.K., Wang, Q.A., Wang, W.T., Wang, W., Wang, X., Wang, X., Wang, Y., Wang, Y., Wang, Y., Wang, Y.Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Z., Wang, Z., Wang, Z., Warnes, G., Warnsmann, V., Watada, H., Watanabe, E., Watchon, M., Wawrzyńska, A., Weaver, T.E., Wegrzyn, G., Wehman, A.M., Wei, H., Wei, L., Wei, T., Wei, Y., Weiergräber, O.H., Weihl, C.C., Weindl, G., Weiskirchen, R., Wells, A., Wen, R.H., Wen, X., Werner, A., Weykopf, B., Wheatley, S.P., Whitton, J.L., Whitworth, A.J., Wiktorska, K., Wildenberg, M.E., Wileman, T., Wilkinson, S., Willbold, D., Williams, B., Williams, R.S.B., Williams, R.L., Williamson, P.R., Wilson, R.A., Winner, B., Winsor, N.J., Witkin, S.S., Wodrich, H., Woehlbier, U., Wollert, T., Wong, E., Wong, J.H., Wong, R.W., Wong, V.K.W., Wong, W.L., Wu, A.G., Wu, C., Wu, J., Wu, J., Wu, K.K., Wu, M., Wu, S.Y., Wu, S., Wu, S.Y., Wu, S., Wu, W.K.K., Wu, X., Wu, X., Wu, Y.W., Wu, Y., Xavier, R.J., Xia, H., Xia, L., Xia, Z., Xiang, G., Xiang, J., Xiang, M., Xiang, W., Xiao, B., Xiao, G., Xiao, H., Xiao, H.T., Xiao, J., Xiao, L., Xiao, S., Xiao, Y., Xie, B., Xie, C.M., Xie, M., Xie, Y., Xie, Z., Xie, Z., Xilouri, M., Xu, C., Xu, E., Xu, H., Xu, J., Xu, J.R., Xu, L., Xu, W.W., Xu, X., Xue, Y., Yakhine-Diop, S.M.S., Yamaguchi, M., Yamaguchi, O., Yamamoto, A., Yamashina, S., Yan, S., Yan, S.J., Yan, Z., Yanagi, Y., Yang, C., Yang, D.S., Yang, H., Yang, H.T., Yang, H., Yang, J.M., Yang, J., Yang, J., Yang, L., Yang, L., Yang, M., Yang, P.M., Yang, Q., Yang, S., Yang, S., Yang, S.F., Yang, W., Yang, W.Y., Yang, X., Yang, X., Yang, Y., Yang, Y., Yao, H., Yao, S., Yao, X., Yao, Y.G., Yao, Y.M., Yasui, T., Yazdankhah, M., Yen, P.M., Yi, C., Yin, X.M., Yin, Y., Yin, Z., Yin, Z., Ying, M., Ying, Z., Yip, C.K., Yiu, S.P.T., Yoo, Y.H., Yoshida, K., Yoshii, S.R., Yoshimori, T., Yousefi, B., Yu, B., Yu, H., Yu, J., Yu, J., Yu, L., Yu, M.L., Yu, S.W., Yu, V.C., Yu, W.H., Yu, Z., Yu, Z., Yuan, J., Yuan, L.Q., Yuan, S., Yuan, S.S.F., Yuan, Y., Yuan, Z., Yue, J., Yue, Z., Yun, J., Yung, R.L., Zacks, D.N., Zaffagnini, G., Zambelli, V.O., Zanella, I., Zang, Q.S., Zanivan, S., Zappavigna, S., Zaragoza, P., Zarbalis, K.S., Zarebkohan, A., Zarrouk, A., Zeitlin, S.O., Zeng, J., Zeng, J.D., Žerovnik, E., Zhan, L., Zhang, B., Zhang, D.D., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H.L., Zhang, J., Zhang, J., Zhang, J.P., Zhang, K.Y.B., Zhang, L.W., Zhang, L., Zhang, L., Zhang, L., Zhang, L., Zhang, M., Zhang, P., Zhang, S., Zhang, W., Zhang, X., Zhang, X.W., Zhang, X., Zhang, X., Zhang, X., Zhang, X., Zhang, X.D., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y.D., Zhang, Y., Zhang, Y.Y., Zhang, Y., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhao, H., Zhao, L., Zhao, S., Zhao, T., Zhao, X.F., Zhao, Y., Zhao, Y., Zhao, Y., Zhao, Y., Zheng, G., Zheng, K., Zheng, L., Zheng, S., Zheng, X.L., Zheng, Y., Zheng, Z.G., Zhivotovsky, B., Zhong, Q., Zhou, A., Zhou, B., Zhou, C., Zhou, G., Zhou, H., Zhou, H., Zhou, H., Zhou, J., Zhou, J., Zhou, J., Zhou, J., Zhou, K., Zhou, R., Zhou, X.J., Zhou, Y., Zhou, Y., Zhou, Y., Zhou, Z.Y., Zhou, Z., Zhu, B., Zhu, C., Zhu, G.Q., Zhu, H., Zhu, H., Zhu, H., Zhu, W.G., Zhu, Y., Zhu, Y., Zhuang, H., Zhuang, X., Zientara-Rytter, K., Zimmermann, C.M., Ziviani, E., Zoladek, T., Zong, W.X., Zorov, D.B., Zorzano, A., Zou, W., Zou, Z., Zou, Z., Zuryn, S., Zwerschke, W., Brand-Saberi, B., Dong, X.C., Kenchappa, C.S., Li, Z., Lin, Y., Oshima, S., Rong, Y., Sluimer, J.C., Stallings, C.L. and Tong, C.K.
Autophagy 17 (1): 1-382. 8 February 2021

Hallmarks and detection techniques of cellular senescence and cellular ageing in immune cells.
Zhou, D., Borsa, M. and Simon, A.K.
Aging Cell 20 (2): e13316. 1 February 2021

The role and uses of antibodies in COVID-19 infections: a living review.
Scourfield, D.C., Reed, S.G., Quastel, M., Alderson, J., Bart, V.M.T., Teijeira Crespo, A., Jones, R., Pring, E., Richter, F.C. and Burnell, S.E.A.
Oxford Open Immunology 2 (1): iqab003. 28 January 2021

Regulating T-cell differentiation through the polyamine spermidine.
Carriche, G.M., Almeida, L., Stüve, P., Velasquez, L., Dhillon-LaBrooy, A., Roy, U., Lindenberg, M., Strowig, T., Plaza-Sirvent, C., Schmitz, I., Lochner, M., Simon, A.K. and Sparwasser, T.
Journal of Allergy and Clinical Immunology 147 (1): 335-348. January 2021

2020

Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses.
Alsaleh, G., Panse, I., Swadling, L., Zhang, H., Richter, F.C., Meyer, A., Lord, J., Barnes, E., Klenerman, P., Green, C. and Simon, A.K.
eLife 9 : e57950. 15 December 2020

Beth Levine 1960-2020.
Simon, A.K. and Mizushima, N.
Nature Cell Biology 22 (8): 909-910. August 2020

Fine-tuning stemness.
Borsa, M. and Simon, A.K.
Science 369 (6502): 373-374. 24 July 2020

Cortical cells are altered by factors including bone morphogenetic protein released from a placental barrier model under altered oxygenation.
Leinster, V.H.L., Phillips, T.J., Jones, N., Sanderson, S., Simon, K., Hanley, J. and Case, C.P.
Neuronal Signaling 4 (1): NS20190148. April 2020

Human liver memory CD8(+) T cells use autophagy for tissue residence.
Swadling, L., Pallett, L.J., Diniz, M.O., Baker, J.M., Amin, O.E., Stegmann, K.A., Burton, A.R., Schmidt, N.M., Jeffery-Smith, A., Zakeri, N., Suveizdyte, K., Froghi, F., Fusai, G., Rosenberg, W.M., Davidson, B.R., Schurich, A., Simon, A.K. and Maini, M.K.
Cell Reports 30 (3): 687-698. 21 January 2020

Polyamines reverse immune senescence via the translational control of autophagy.
Zhang, H. and Simon, A.K.
Autophagy 16 (1): 181-182. January 2020

2019

Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence.
Zhang, H., Alsaleh, G., Feltham, J., Sun, Y., Napolitano, G., Riffelmacher, T., Charles, P., Frau, L., Hublitz, P., Yu, Z., Mohammed, S., Ballabio, A., Balabanov, S., Mellor, J. and Simon, A.K.
Molecular Cell 76 (1): 110-125. 3 October 2019

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Cossarizza, A., Chang, H.D., Radbruch, A., Acs, A., Adam, D., Adam-Klages, S., Agace, W.W., Aghaeepour, N., Akdis, M., Allez, M., Almeida, L.N., Alvisi, G., Anderson, G., Andrä, I., Annunziato, F., Anselmo, A., Bacher, P., Baldari, C.T., Bari, S., Barnaba, V., Barros-Martins, J., Battistini, L., Bauer, W., Baumgart, S., Baumgarth, N., Baumjohann, D., Baying, B., Bebawy, M., Becher, B., Beisker, W., Benes, V., Beyaert, R., Blanco, A., Boardman, D.A., Bogdan, C., Borger, J.G., Borsellino, G., Boulais, P.E., Bradford, J.A., Brenner, D., Brinkman, R.R., Brooks, A.E.S., Busch, D.H., Büscher, M., Bushnell, T.P., Calzetti, F., Cameron, G., Cammarata, I., Cao, X., Cardell, S.L., Casola, S., Cassatella, M.A., Cavani, A., Celada, A., Chatenoud, L., Chattopadhyay, P.K., Chow, S., Christakou, E., Čičin-Šain, L., Clerici, M., Colombo, F.S., Cook, L., Cooke, A., Cooper, A.M., Corbett, A.J., Cosma, A., Cosmi, L., Coulie, P.G., Cumano, A., Cvetkovic, L., Dang, V.D., Dang-Heine, C., Davey, M.S., Davies, D., De Biasi, S., Del Zotto, G., Dela Cruz, G.V., Delacher, M., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Di Santo, J.P., Diefenbach, A., Dieli, F., Dolf, A., Dörner, T., Dress, R.J., Dudziak, D., Dustin, M., Dutertre, C.A., Ebner, F., Eckle, S.B.G., Edinger, M., Eede, P., Ehrhardt, G.R.A., Eich, M., Engel, P., Engelhardt, B., Erdei, A., Esser, C., Everts, B., Evrard, M., Falk, C.S., Fehniger, T.A., Felipo-Benavent, M., Ferry, H., Feuerer, M., Filby, A., Filkor, K., Fillatreau, S., Follo, M., Förster, I., Foster, J., Foulds, G.A., Frehse, B., Frenette, P.S., Frischbutter, S., Fritzsche, W., Galbraith, D.W., Gangaev, A., Garbi, N., Gaudilliere, B., Gazzinelli, R.T., Geginat, J., Gerner, W., Gherardin, N.A., Ghoreschi, K., Gibellini, L., Ginhoux, F., Goda, K., Godfrey, D.I., Goettlinger, C., González-Navajas, J.M., Goodyear, C.S., Gori, A., Grogan, J.L., Grummitt, D., Grützkau, A., Haftmann, C., Hahn, J., Hammad, H., Hämmerling, G., Hansmann, L., Hansson, G., Harpur, C.M., Hartmann, S., Hauser, A., Hauser, A.E., Haviland, D.L., Hedley, D., Hernández, D.C., Herrera, G., Herrmann, M., Hess, C., Höfer, T., Hoffmann, P., Hogquist, K., Holland, T., Höllt, T., Holmdahl, R., Hombrink, P., Houston, J.P., Hoyer, B.F., Huang, B., Huang, F.P., Huber, J.E., Huehn, J., Hundemer, M., Hunter, C.A., Hwang, W.Y.K., Iannone, A., Ingelfinger, F., Ivison, S.M., Jäck, H.M., Jani, P.K., Jávega, B., Jonjic, S., Kaiser, T., Kalina, T., Kamradt, T., Kaufmann, S.H.E., Keller, B., Ketelaars, S.L.C., Khalilnezhad, A., Khan, S., Kisielow, J., Klenerman, P., Knopf, J., Koay, H.F., Kobow, K., Kolls, J.K., Kong, W.T., Kopf, M., Korn, T., Kriegsmann, K., Kristyanto, H., Kroneis, T., Krueger, A., Kühne, J., Kukat, C., Kunkel, D., Kunze-Schumacher, H., Kurosaki, T., Kurts, C., Kvistborg, P., Kwok, I., Landry, J., Lantz, O., Lanuti, P., LaRosa, F., Lehuen, A., LeibundGut-Landmann, S., Leipold, M.D., Leung, L.Y.T., Levings, M.K., Lino, A.C., Liotta, F., Litwin, V., Liu, Y., Ljunggren, H.G., Lohoff, M., Lombardi, G., Lopez, L., López-Botet, M., Lovett-Racke, A.E., Lubberts, E., Luche, H., Ludewig, B., Lugli, E., Lunemann, S., Maecker, H.T., Maggi, L., Maguire, O., Mair, Fl., Mair, K.H., Mantovani, A., Manz, R.A., Marshall, A.J., Martínez-Romero, A., Martrus, G., Marventano, I., Maslinski, W., Matarese, G., Mattioli, A.V., Maueröder, C., Mazzoni, A., McCluskey, J., McGrath, M., McGuire, H.M., McInnes, I.B., Mei, H.E., Melchers, F., Melzer, S., Mielenz, D., Miller, S.D., Mills, K.H.G., Minderman, H., Mjösberg, J., Moore, J., Moran, B., Moretta, L., Mosmann, T.R., Müller, S., Multhoff, G., Muñoz, L.E., Münz, C., Nakayama, T., Nasi, M., Neumann, K., Ng, L.G., Niedobitek, A., Nourshargh, S., Núñez, G., O'Connor, J.E., Ochel, A., Oja, A., Ordonez, D., Orfao, A., Orlowski-Oliver, E., Ouyang, W., Oxenius, A., Palankar, R., Panse, I., Pattanapanyasat, K., Paulsen, M., Pavlinic, D., Penter, L., Peterson, P., Peth, C., Petriz, J., Piancone, F., Pickl, W.F., Piconese, S., Pinti, M., Pockley, A.G., Podolska, M.J., Poon, Z., Pracht, K., Prinz, I., Pucillo, C.E.M., Quataert, S.A., Quatrini, L., Quinn, K.M., Radbruch, H., Radstake, T.R.D.J., Rahmig, S., Rahn, H.P., Rajwa, B., Ravichandran, G., Raz, Y., Rebhahn, J.A., Recktenwald, D., Reimer, D., Reis E Sousa, C., Remmerswaal, E.B.M., Richter, L., Rico, L.G., Riddell, A., Rieger, A.M., Robinson, J.P, Romagnani, C., Rubartelli, A., Ruland, J., Saalmüller, A., Saeys, Y., Saito, T., Sakaguchi, S., Sala-de-Oyanguren, F., Samstag, Y., Sanderson, S., Sandrock, I., Santoni, A., Sanz, R.B., Saresella, M., Sautes-Fridman, C., Sawitzki, B., Schadt, L., Scheffold, A., Scherer, H.U, Schiemann, M., Schildberg, F.A., Schimisky, E., Schlitzer, A., Schlosser, J., Schmid, S., Schmitt, S., Schober, K., Schraivogel, D., Schuh, W., Schüler, T., Schulte, R., Schulz, A.R., Schulz, S.R., Scottá, C., Scott-Algara, D., Sester, D.P., Shankey, T.V., Silva-Santos, B., Simon, A.K., Sitnik, K.M., Sozzani, S., Speiser, D.E., Spidlen, J., Stahlberg, A., Stall, A.M., Stanley, N., Stark, R., Stehle, C., Steinmetz, T., Stockinger, H., Takahama, Y., Takeda, K., Tan, L., Tárnok, A., Tiegs, G., Toldi, G., Tornack, J., Traggiai, E., Trebak, M., Tree, T.I.M., Trotter, J., Trowsdale, J., Tsoumakidou, M., Ulrich, H., Urbanczyk, S., van de Veen, W., van den Broek, M., van der Pol, E., Van Gassen, S., Van Isterdael, G., van Lier, R.A.W., Veldhoen, M., Vento-Asturias, S., Vieira, P., Voehringer, D., Volk, H.D., von Borstel, A., von Volkmann, K., Waisman, A., Walker, R.V., Wallace, P.K., Wang, S.A., Wang, X.M., Ward, M.D., Ward-Hartstonge, K.A., Warnatz, K., Warnes, G., Warth, S., Waskow, C., Watson, J.V., Watzl, C., Wegener, L., Weisenburger, T., Wiedemann, A., Wienands, J., Wilharm, A., Wilkinson, R.J., Willimsky, G., Wing, J.B., Winkelmann, R., Winkler, T.H., Wirz, O.F., Wong, A., Wurst, P., Yang, J.H.M., Yang, J., Yazdanbakhsh, M., Yu, L., Yue, A., Zhang, H., Zhao, Y., Ziegler, S.M., Zielinski, C., Zimmermann, J. and Zychlinsky, A.
European Journal of Immunology 49 (10): 1457-1973. October 2019

Insights into pancreatic β cell energy metabolism using rodent β cell models.
Morten, K.J., Potter, M., Badder, L., Sivathondan, P., Dragovic, R., Neumann, A., Gavin, J., Shrestha, R., Reilly, S., Phadwal, K., Lodge, T.A., Borzychowski, A., Cookson, S., Mitchell, C., Morovat, A., Simon, A.K., Uusimaa, J., Hynes, J. and Poulton, J.
Wellcome Open Research 2 : 14. 25 September 2019

Autophagy in the renewal, differentiation and homeostasis of immune cells.
Clarke, A.J. and Simon, A.K.
Nature Reviews Immunology 19 (3): 170-183. March 2019

2018

Local exchange of metabolites shapes immunity.
Richter, F.C., Obba, S. and Simon, A.K.
Immunology 155 (3): 309-319. November 2018

A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation.
Breglio, K.F., Amato, R., Eastman, R., Lim, P., Sa, J.M., Guha, R., Ganesan, S., Dorward, D.W., Klumpp-Thomas, C., McKnight, C., Fairhurst, R.M., Roberts, D., Thomas, C. and Simon, A.K.
Malaria Journal 17 (1): 391. 26 October 2018

Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells.
Smith, A.M., Depp, C., Ryan, B.J., Johnston, G.I., Alegre-Abarrategui, J., Evetts, S., Rolinski, M., Baig, F., Ruffmann, C., Simon, A.K., Hu, M.T.M. and Wade-Martins, R.
Movement Disorders 33 (10): 1580-1590. October 2018

B1a B cells require autophagy for metabolic homeostasis and self-renewal.
Clarke, A.J., Riffelmacher, T., Braas, D., Cornall, R.J. and Simon, A.K.
Journal of Experimental Medicine 215 (2): 399-413. 5 February 2018

Autophagy dictates metabolism and differentiation of inflammatory immune cells.
Riffelmacher, T., Richter, F.C. and Simon, A.K.
Autophagy 14 (2): 199-206. 2018

2017

In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay.
Sanderson, S.L. and Simon, A.K.
Aging Cell 16 (6): 1234-1243. December 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (first edition).
Cossarizza, A., Chang, H.D., Radbruch, A., Akdis, M., Andrä, I., Annunziato, F., Bacher, P., Barnaba, V., Battistini, L., Bauer, W.M., Baumgart, S., Becher, B., Beisker, W., Berek, C., Blanco, A., Borsellino, G., Boulais, P.E., Brinkman, R.R., Büscher, M., Busch, D.H., Bushnell, T.P., Cao, X., Cavani, A., Chattopadhyay, P.K., Cheng, Q., Chow, S., Clerici, M., Cooke, A., Cosma, A., Cosmi, L., Cumano, A., Dang, V.D., Davies, D., De Biasi, S., Del Zotto, G., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Diefenbach, A., Di Santo, J., Dieli, F., Dolf, A., Donnenberg, V.S., Dörner, T., Ehrhardt, G.R.A., Endl, E., Engel, P., Engelhardt, B., Esser, C., Everts, B., Dreher, A., Falk, C.S., Fehniger, T.A., Filby, A., Fillatreau, S., Follo, M., Förster, I., Foster, J., Foulds, G.A., Frenette, P.S., Galbraith, D., Garbi, N., García-Godoy, M.D., Geginat, J., Ghoreschi, K., Gibellini, L., Goettlinger, C., Goodyear, C.S., Gori, A., Grogan, J., Gross, M., Grützkau, A., Grummitt, D., Hahn, J., Hammer, Q., Hauser, A.E., Haviland, D.L., Hedley, D., Herrera, G., Herrmann, M., Hiepe, F., Holland, T., Hombrink, P., Houston, J.P., Hoyer, B.F., Huang, B., Hunter, C.A., Iannone, A., Jäck, H.M., Jávega, B., Jonjic, S., Juelke, K., Jung, S., Kaiser, T., Kalina, T., Keller, B., Khan, S., Kienhöfer, D., Kroneis, T., Kunkel, D., Kurts, C., Kvistborg, P., Lannigan, J., Lantz, O., Larbi, A., LeibundGut-Landmann, S., Leipold, M.D., Levings, M.K., Litwin, V., Liu, Y., Lohoff, M., Lombardi, G., Lopez, L., Lovett-Racke, A., Lubberts, E., Ludewig, B., Lugli, E., Maecker, H.T., Martrus, G., Matarese, G., Maueröder, C., McGrath, M., McInnes, I., Mei, H.E., Melchers, F., Melzer, S., Mielenz, D., Mills, K., Mirrer, D., Mjösberg, J., Moore, J., Moran, B., Moretta, A., Moretta, L., Mosmann, T.R., Müller, S., Müller, W., Münz, C., Multhoff, G., Munoz, L.E., Murphy, K.M., Nakayama, T., Nasi, M., Neudörfl, C., Nolan, J., Nourshargh, S., O'Connor, J.E., Ouyang, W., Oxenius, A., Palankar, R., Panse, I., Peterson, P., Peth, C., Petriz, J., Philips, D., Pickl, W., Piconese, S., Pinti, M., Pockley, A.G., Podolska, M.J., Pucillo, C., Quataert, S.A., Radstake, T.R.D.J., Rajwa, B., Rebhahn, J.A., Recktenwald, D., Remmerswaal, E.B.M., Rezvani, K., Rico, L.G., Robinson, J.P., Romagnani, C., Rubartelli, A., Ruckert, B., Ruland, J., Sakaguchi, S., Sala-de-Oyanguren, F., Samstag, Y., Sanderson, S., Sawitzki, B., Scheffold, A., Schiemann, M., Schildberg, F., Schimisky, E., Schmid, S.A., Schmitt, S., Schober, K., Schüler, T., Schulz, A.R., Schumacher, T., Scotta, C., Shankey, T.V., Shemer, A., Simon, A.K., Spidlen, J., Stall, A.M., Stark, R., Stehle, C., Stein, M., Steinmetz, T., Stockinger, H., Takahama, Y., Tarnok, A., Tian, Z.G., Toldi, G., Tornack, J., Traggiai, E., Trotter, J., Ulrich, H., van der Braber, M., van Lier, R.A.W., Veldhoen, M., Vento-Asturias, S., Vieira, P., Voehringer, D., Volk, H.D., von Volkmann, K., Waisman, A., Walker, R., Ward, M.D., Warnatz, K., Warth, S., Watson, J.V., Watzl, C., Wegener, L., Wiedemann, A., Wienands, J., Willimsky, G., Wing, J., Wurst, P., Yu, L., Yue, A., Zhang, Q., Zhao, Y., Ziegler, S. and Zimmermann, J.
European Journal of Immunology 47 (10): 1584-1797. 11 October 2017

Autophagy-dependent generation of free fatty acids is critical for normal neutrophil differentiation.
Riffelmacher, T., Clarke, A., Richter, F.C., Stranks, A., Pandey, S., Danielli, S., Hublitz, P., Yu, Z., Johnson, E., Schwerd, T., McCullagh, J., Uhlig, H., Jacobsen, S.E.W. and Simon, A.K.
Immunity 47 (3): 466-480.e5. 19 September 2017

Molecular definitions of autophagy and related processes.
Galluzzi, L., Baehrecke, E.H., Ballabio, A., Boya, P., Bravo-San Pedro, J.M., Cecconi, F., Choi, A.M., Chu, C.T., Codogno, P., Colombo, M.I., Cuervo, A.M., Debnath, J., Deretic, V., Dikic, I., Eskelinen, E.L., Fimia, G.M., Fulda, S., Gewirtz, D.A., Green, D.R., Hansen, M., Harper, J.W., Jäättelä, M., Johansen, T., Juhasz, G., Kimmelman, A.C., Kraft, C., Ktistakis, N.T., Kumar, S., Levine, B., Lopez-Otin, C., Madeo, F., Martens, S., Martinez, J., Melendez, A., Mizushima, N., Münz, C., Murphy, L.O., Penninger, J.M., Piacentini, M., Reggiori, F., Rubinsztein, D.C., Ryan, K.M., Santambrogio, L., Scorrano, L., Simon, A.K., Simon, H.U., Simonsen, A., Tavernarakis, N., Tooze, S.A., Yoshimori, T., Yuan, J., Yue, Z., Zhong, Q. and Kroemer, G.
EMBO Journal 36 (13): 1811-1836. 3 July 2017

Mechanistic roles of autophagy in hematopoietic differentiation.
Riffelmacher, T. and Simon, A.K.
FEBS Journal 284 (7): 1008-1020. April 2017

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.
Liao, C., Ashley, N., Diot, A., Morten, K., Phadwal, K., Williams, A., Fearnley, I., Rosser, L., Lowndes, J., Fratter, C., Ferguson, D.J.P., Vay, L., Quaghebeur, G., Moroni, I., Bianchi, S., Lamperti, C., Downes, S.M., Sitarz, K.S., Flannery, P.J., Carver, J., Dombi, E., East, D., Laura, M., Reilly, M.M., Mortiboys, H., Prevo, R., Campanella, M., Daniels, M.J., Zeviani, M., Yu-Wai-Man, P., Simon, A.K., Votruba, M. and Poulton, J.
Neurology 88 (2): 131-142. 10 January 2017

2016

Exposure to zidovudine adversely affects mitochondrial turnover in primary T cells.
Wallace, Z.R., Sanderson, S., Simon, A.K. and Dorrell, L.
Antiviral Research 133 : 178-82. September 2016

Autophagy in T and B lymphocytes.
Clarke, A.J. and Simon, A.K.
Autophagy Networks in Inflammation : 171-184. 25 August 2016

Autophagy and immune senescence.
Zhang, H., Puleston, D.J. and Simon, A.K.
Trends in Molecular Medicine 22 (8): 671-686. August 2016

Non-canonical autophagy LAPs lupus.
Simon, A.K. and Clarke, A.J.
Cell Death and Differentiation 23 (8): 1267-8. August 2016

The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.
Kabat, A.M., Harrison, O.J., Riffelmacher, T., Moghaddam, A.E., Pearson, C.F., Laing, A., Abeler-Dörner, L., Forman, S.P., Grencis, R.K., Sattentau, Q., Simon, A.K., Pott, J. and Maloy, K.J.
eLife 5 : e12444. 11 March 2016

2015

Evolution of the immune system in humans from infancy to old age.
Simon, A.K., Hollander, G.A. and McMichael, A.
Proceedings of the Royal Society of London Series B-Biological Sciences 282 (1821): 20143085. 22 December 2015

Current questions and possible controversies in autophagy.
Lindqvist, L.M., Simon, A.K. and Baehrecke, E.H.
Cell Death Discovery 1 : 15036. 9 November 2015

Techniques for the detection of autophagy in primary mammalian cells.
Puleston, D., Phadwal, K., Watson, A.S., Soilleux, E.J., Chittaranjan, S., Bortnik, S., Gorski, S.M., Ktistakis, N. and Simon, A.K.
Cold Spring Harbor Protocols 2015 (9): pdb.top070391. 1 September 2015

Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia.
Watson, A.S., Riffelmacher, T., Stranks, A., Williams, O., De Boer, J., Cain, K., MacFarlane, M., McGouran, J., Kessler, B., Khandwala, S., Chowdhury, O., Puleston, D., Phadwal, K., Mortensen, M., Ferguson, D., Soilleux, E., Woll, P., Jacobsen, S.E.W. and Simon, A.K.
Cell Death Discovery 1 : 15008. 17 August 2015

Autophagy controls acquisition of aging features in macrophages.
Stranks, A.J., Hansen, A.L., Panse, I., Mortensen, M., Ferguson, D.J.P., Puleston, D.J., Shenderov, K., Watson, A.S., Veldhoen, M., Phadwal, K., Cerundolo, V. and Simon, A.K.
Journal of Innate Immunity 7 (4): 375-391. June 2015

Autophagy is activated in systemic lupus erythematosus and required for plasmablast development.
Clarke, A.J., Ellinghaus, U., Cortini, A., Stranks, A., Simon, A.K., Botto, M. and Vyse, T.J.
Annals of the Rheumatic Diseases 74 (5): 912-20. May 2015

New roles for autophagy and spermidine in T cells.
Puleston, D.J. and Simon, A.K.
Microbial Cell 2 (3): 91-93. March 2015

An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease.
Pienaar, I.S., Harrison, I.F., Elson, J.L., Bury, A., Woll, P., Simon, A.K. and Dexter, D.T.
Brain Structure & Function 220 (1): 479-500. January 2015

Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.
Jabir, M.S., Hopkins, L., Ritchie, N.D., Ullah, I., Bayes, H.K., Li, D., Tourlomousis, P., Lupton, A., Puleston, D., Simon, A.K., Bryant, C. and Evans, T.J.
Autophagy 11 (1): 166-182. 2015

2014

Essential role for autophagy during invariant NKT cell development.
Salio, M., Puleston, D.J., Mathan, T.S.M., Shepherd, D., Stranks, A.J., Adamopoulou, E., Veerapen, N., Besra, G.S., Hollander, G.A., Simon, A.K. and Cerundolo, V.
Proceedings of the National Academy of Sciences of the United States of America 111 (52): E5678-E5687. 30 December 2014

Dual proteolytic pathways govern glycolysis and immune competence.
Lu, W., Zhang, Y., McDonald, D.O., Jing, H., Carroll, B., Robertson, N., Zhang, Q., Griffin, H., Sanderson, S., Lakey, J.H., Morgan, N.V., Reynard, L.N., Zheng, L., Murdock, H.M., Turvey, S.E., Hackett, S.J., Prestidge, T., Hall, J.M., Cant, A.J., Matthews, H.F., Koref, M.F.S., Simon, A.K., Korolchuk, V.I., Lenardo, M.J., Hambleton, S. and Su, H.C.
Cell 159 (7): 1578-1590. 18 December 2014

Autophagy is a critical regulator of memory CD8(+) T cell formation.
Puleston, D.J., Zhang, H., Powell, T.J., Lipina, E., Sims, S., Panse, I., Watson, A.S., Cerundolo, V., Townsend, A.R., Klenerman, P. and Simon, A.K.
eLife 3 : e03706. 11 November 2014

Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions.
Curtis, D.J., Sood, A., Phillips, T.J., Leinster, V.H.L., Nishiguchi, A., Coyle, C., Lacharme-Lora, L., Beaumont, O., Kemp, H., Goodall, R., Cornes, L., Giugliano, M., Barone, R.A., Matsusaki, M., Akashi, M., Tanaka, H.Y., Kano, M., McGarvey, J., Halemani, N.D., Simon, K., Keehan, R., Ind, W., Masters, T., Grant, S., Athwal, S., Collett, G., Tannetta, D., Sargent, I.L., Scull-Brown, E., Liu, X., Aquilina, K., Cohen, N., Lane, J.D., Thoresen, M., Hanley, J., Randall, A. and Case, C.P.
Experimental Neurology 261 : 386-395. November 2014

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8(+) T cells.
Henson, S.M., Lanna, A., Riddell, N.E., Franzese, O., Macaulay, R., Griffiths, S.J., Puleston, D.J., Watson, A.S., Simon, A.K., Tooze, S.A. and Akbar, A.N.
Journal of Clinical Investigation 124 (9): 4004-4016. 2 September 2014

Caspase-1 cleavage of the TLR adaptor TRIF inhibits autophagy and β-interferon production during Pseudomonas aeruginosa infection.
Jabir, M.S., Ritchie, N.D., Li, D., Bayes, H.K., Tourlomousis, P., Puleston, D., Lupton, A., Hopkins, L., Simon, A.K., Bryant, C. and Evans, T.J.
Cell Host & Microbe 15 (2): 214-227. 12 February 2014

Autophagy in the immune system.
Puleston, D.J. and Simon, A.K.
Immunology 141 (1): 1-8. January 2014

2013

Autophagy in stem cells.
Guan, J.L., Simon, A.K., Prescott, M., Menendez, J.A., Liu, F., Wang, F., Wang, C., Wolvetang, E., Vazquez-Martin, A. and Zhang, J.
Autophagy 9 (6): 830-949. June 2013

Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival.
Pike, L.R.G., Singleton, D.C., Buffa, F., Abramczyk, O., Phadwal, K., Li, J.L., Simon, A.K., Murray, J.T. and Harris, A.L.
Biochemical Journal 449 (2): 389-400. 15 January 2013

T. rex attacks the lysosome.
Simon, A.K. and Ballabio, A.
Nature Immunology 14 (1): 10-2. January 2013

Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging.
Phadwal, K., Watson, A.S. and Simon, A.K.
Cellular and Molecular Life Sciences 70 (1): 89-103. January 2013

2012

ATF4 orchestrates a program of BH3-only protein expression in severe hypoxia.
Pike, L.R.G., Phadwal, K., Simon, A.K. and Harris, A.L
Molecular Biology Reports 39 (12): 10811-22. December 2012

Gender equality: is it real?
Simon, K., Athanassakis, I., Powrie, F. and Montoya, M.
European Journal of Immunology 42 (12): 3095-6. December 2012

Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity.
Lopez-Herrera, G., Tampella, G., Pan-Hammarström, Q., Herholz, P., Trujillo-Vargas, C.M., Phadwal, K., Simon, A.K., Moutschen, M., Etzioni, A., Mory, A., Srugo, I., Melamed, D., Hultenby, K., Liu, C., Baronio, M., Vitali, M., Philippet, P., Dideberg, V., Aghamohammadi, A., Rezaei, N., Enright, V., Du, L., Salzer, U., Eibel, H., Pfeifer, D., Veelken, H., Stauss, H., Lougaris, V., Plebani, A., Gertz, E.M., Schäffer, A.A., Hammarström, L. and Grimbacher, B.
American Journal of Human Genetics 90 (6): 986-1001. 8 June 2012

The immune response to melanoma is limited by thymic selection of self-antigens.
Träger, U., Sierro, S., Djordjevic, G., Bouzo, B., Khandwala, S., Meloni, A., Mortensen, M. and Simon, A.K.
PLoS ONE 7 (4): e35005. 10 April 2012

A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Phadwal, K., Alegre-Abarrategui, J., Watson, A.S., Pike, L., Anbalagan, S., Hammond, E.M., Wade-Martins, R., McMichael, A., Klenerman, P. and Simon, A.K.
Autophagy 8 (4): 677-89. 1 April 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.
Klionsky, D.J., Abdalla, F.C., Abeliovich, H., Abraham, R.T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Milojkovic, A. and Simon, A.K.
Autophagy 8 (4): 445-544. April 2012

Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.
Roberts, N.A., White, A.J., Jenkinson, W.E., Turchinovich, G., Nakamura, K., Withers, D.R., McConnell, F.M., Desanti, G.E., Benezech, C., Parnell, S.M., Cunningham, A.F., Paolino, M., Penninger, J.M., Simon, A.K., Nitta, T., Ohigashi, I., Takahama, Y., Caamano, J.H., Hayday, A.C., Lane, P.J.L., Jenkinson, E.J. and Anderson, G.
Immunity 36 (3): 427-37. 23 March 2012

2011

HspB8 mutation causing hereditary distal motor neuropathy impairs lysosomal delivery of autophagosomes.
Kwok, A.S., Phadwal, K., Turner, B.J., Oliver, P.L., Raw, A., Simon, A.K., Talbot, K. and Agashe, V.R.
Journal of Neurochemistry 119 (6): 1155-61. December 2011

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness.
Sood, A., Salih, S., Roh, D., Lacharme-Lora, L., Parry, M., Hardiman, B., Keehan, R., Grummer, R., Winterhager, E., Gokhale, P.J., Andrews, P.W., Abbott, C., Forbes, K., Westwood, M., Aplin, J.D., Ingham, E., Papageorgiou, I., Berry, M., Liu, J., Dick, A.D., Garland, R.J., Williams, N., Singh, R., Simon, A.K., Lewis, M., Ham, J., Roger, L., Baird, D.M., Crompton, L.A., Caldwell, M.A., Swalwell, H., Birch-Machin, M., Lopez-Castejon, G., Randall, A., Lin, H., Suleiman, M.S., Evans, W.H., Newson, R. and Case, C.P.
Nature Nanotechnology 6 (12): 824-33. December 2011

Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes.
Rasmussen, S.B., Horan, K.A., Holm, C.K., Stranks, A.J., Mettenleiter, T.C., Simon, A.K., Jensen, S.B., Rixon, F.J., He, B. and Paludan, S.R.
Journal of Immunology 187 (10): 5268-76. 15 November 2011

Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation.
Mortensen, M., Watson, A.S. and Simon, A.K.
Autophagy 7 (9): 1069-70. September 2011

Autophagy in the pathogenesis of myelodysplastic syndrome and acute myeloid leukemia.
Watson, A.S., Mortensen, M. and Simon, A.K.
Cell Cycle 10 (11): 1719-25. 1 June 2011

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.
Mortensen, M., Soilleux, E.J., Djordjevic, G., Tripp, R., Lutteropp, M., Sadighi-Akha, E., Stranks, A.J., Glanville, J., Knight, S., Jacobsen, S.E.W., Kranc, K.R. and Simon, A.K.
Journal of Experimental Medicine 208 (3): 455-67. 14 March 2011

2010

Novel role of regulatory T cells in limiting early neutrophil responses in skin.
Richards, H., Williams, A., Jones, E., Hindley, J., Godkin, A., Simon, A.K. and Gallimore, A.
Immunology 131 (4): 583-92. December 2010

Mitochondrial clearance by autophagy in developing erythrocytes: clearly important, but just how much so?
Mortensen, M., Ferguson, D.J.P. and Simon, A.K.
Cell Cycle 9 (10): 1901-6. 31 May 2010

Nonredundant role of Atg7 in mitochondrial clearance during erythroid development.
Mortensen, M. and Simon, A.K.
Autophagy 6 (3): 423-5. 1 April 2010

Potent adaptive immune responses induced against HIV-1 gp140 and influenza virus HA by a polyanionic carbomer.
Krashias, G., Simon, A.K., Wegmann, F., Kok, W.L., Ho, L.P., Stevens, D., Skehel, J., Heeney, J.L., Moghaddam, A.E. and Sattentau, Q.J.
Vaccine 28 (13): 2482-9. 16 March 2010

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo.
Mortensen, M., Ferguson, D.J.P., Edelmann, M., Kessler, B., Morten, K.J., Komatsu, M. and Simon, A.K.
Proceedings of the National Academy of Sciences of the United States of America 107 (2): 832-7. 12 January 2010

Depletion of CD4+CD25+ regulatory T cells enhances natural killer T cell-mediated anti-tumour immunity in a murine mammary breast cancer model.
Hong, H., Gu, Y., Zhang, H., Simon, A.K., Chen, X., Wu, C., Xu, X.N. and Jiang, S.
Clinical and Experimental Immunology 159 (1): 93-9. January 2010

2009

Enhanced immune recognition of cryptic glycan markers in human tumors.
Newsom-Davis, T.E., Wang, D., Steinman, L., Chen, P.F.T., Wang, L.X., Simon, A.K. and Screaton, G.R.
Cancer Research 69 (5): 2018-25. 1 March 2009

2008

Positive and negative influences of regulatory T cells on tumour immunity.
Gallimore, A.M. and Simon, A.K.
Oncogene 27 (45): 5886-93. 6 October 2008

BAC-mediated transgenic expression of fluorescent autophagic protein Beclin 1 reveals a role for Beclin 1 in lymphocyte development.
Arsov, I., Li, X., Matthews, G., Coradin, J., Hartmann, B., Simon, A.K., Sealfon, S.C. and Yue, Z.
Cell Death and Differentiation 15 (9): 1385-95. September 2008

Generation of tumour-rejecting anti-carbohydrate monoclonal antibodies using melanoma modified with Fas ligand.
Simon, A.K., Newsom-Davis, T., Frayne, M.E.F., Ch'en, P.F.T., McMichael, A.J. and Screaton, G.R.
International Immunology 20 (4): 525-34. April 2008

2007

Regulatory T cells inhibit Fas ligand-induced innate and adaptive tumour immunity.
Simon, A.K., Jones, E., Richards, H., Wright, K., Betts, G., Godkin, A., Screaton, G. and Gallimore, A.
European Journal of Immunology 37 (3): 758-67. March 2007

2004

The influence of CD25+ cells on the generation of immunity to tumour cell lines in mice.
Jones, E., Golgher, D., Simon, A.K., Dahm-Vicker, M., Screaton, G., Elliott, T. and Gallimore, A.
In: Novartis Foundation Symposium 256. 2004

2003

A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouse.
Isaacs, A.M., Oliver, P.L., Jones, E.L., Jeans, A., Potter, A., Hovik, B.H., Nolan, P.M., Vizor, L., Glenister, P., Simon, A.K., Gray, I.C., Spurr, N.K., Brown, S.D.M., Hunter, A.J. and Davies, K.E.
Journal of Neuroscience 23 (5): 1631-7. 1 March 2003

2002

Fas ligand breaks tolerance to self-antigens and induces tumor immunity mediated by antibodies.
Simon, A.K., Gallimore, A., Jones, E., Sawitzki, B., Cerundolo, V. and Screaton, G.R.
Cancer Cell 2 (4): 315-22. October 2002

Suicide determines self.
Medema, J.P. and Simon, A.K.
Cell Death and Differentiation 9 (4): 364-6. 1 April 2002

Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice.
Jones, E., Dahm-Vicker, M., Simon, A.K., Green, A., Powrie, F., Cerundolo, V. and Gallimore, A.
Cancer Immunity 2 : 1. February 2002

2001

Tumor necrosis factor-related apoptosis-inducing ligand in T cell development: sensitivity of human thymocytes.
Simon, A.K., Williams, O., Mongkolsapaya, J., Jin, B., Xu, X.N., Walczak, H. and Screaton, G.R.
Proceedings of the National Academy of Sciences of the United States of America 98 (9): 5158-63. 24 April 2001

2000

The lack of NF-kappa B transactivation and PKC epsilon expression in CD4(+)CD8(+) thymocytes correlates with negative selection.
Simon, A.K., Auphan, N., Pophillat, M., Boyer, C., Ghosh, S., Rincón, M., Flavell, R.A. and Schmitt-Verhulst, A.M.
Cell Death and Differentiation 7 (12): 1253-62. 1 December 2000

1998

Consequences of intrathymic TCR engagement by partial agonist on selection events and peripheral T cell activation program.
Auphan, N., Simon, A.K., Asnagli, H., Phillips, R.J., Rincon, M., Ghosh, S., Flavell, R.A. and Schmitt-Verhulst, A.M.
Journal of Immunology 160 (10): 4810-21. 15 May 1998

1997

Interferon-regulatory factors during development of CD4 and CD8 thymocytes.
Simon, A.K., Desrois, M. and Schmitt-Verhulst, A.M.
Immunology 91 (3): 340-5. July 1997

1996

Developmental control of antigen-induced thymic transcription factors.
Simon, A.K., Auphan, N. and Schmitt-Verhulst, A.M.
International Immunology 8 (9): 1421-8. 1 September 1996

1995

Two signaling pathways can lead to Fas ligand expression in CD8+ cytotoxic T lymphocyte clones.
Anel, A., Simon, A.K., Auphan, N., Buferne, M., Boyer, C., Golstein, P. and Schmitt-Verhulst, A.M.
European Journal of Immunology 25 (12): 3381-7. December 1995

1994

Divergent T-cell cytokine patterns in inflammatory arthritis.
Simon, A.K., Seipelt, E. and Sieper, J.
Proceedings of the National Academy of Sciences of the United States of America 91 (18): 8562-6. 30 August 1994

1993

Analysis of cytokine profiles in synovial T cell clones from chlamydial reactive arthritis patients: predominance of the Th1 subset.
Simon, A.K., Seipelt, E., Wu, P., Wenzel, B., Braun, J. and Sieper, J.
Clinical and Experimental Immunology 94 (1): 122-6. October 1993

In situ localization of HLA class I mRNA in human testis.
Janitz, M., Fiszer, D., Jaruzelska, J., Simon, A.K., Biro, A., Sachs, J.A. and Kurpisz, M.
Experimental and Clinical Immunogenetics 10 (4): 202-7. 1993

1992

Tolerance of self induced in thymus organ culture.
Robertson, K., Simon, K., Schneider, S., Timms, E. and Mitchison, A.
European Journal of Immunology 22 (1): 207-11. January 1992

1990

Purification of recombinant Mycobacterium leprae 65-kilodalton antigen and murine antibody responses to intravenously administered recombinant protein.
Char, S., Colston, M.J., Mitchison, N.A. and Simon, K.
Tropical Medicine and Parasitology 41 (3): 336-8. September 1990

Dominant reduced responsiveness controlled by H-2(Kb)Ab. A new pattern evoked by Thy-1 antigen and F liver antigen.
Mitchison, N.A. and Simon, K.
Immunogenetics 32 (2): 104-9. August 1990