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2024

Next questions in autophagy.
Cuervo, A.M. and Elazar, Z. and Evans, C. and Ge, L. and Hansen, M. and Jäättelä, M. and Liang, J.R.A. and Loos, B. and Mizushima, N. and Simon, A.K. and Tooze, S. and Yoshimori, T. and Nakamura, S.
Nature Cell Biology 26 (5): 661-666. May 2024

Blocking glycosphingolipid production alters autophagy in osteoclasts and improves myeloma bone disease.
Leng, H. and Simon, A.K. and Horwood, N.J.
Autophagy 20 (4): 930-932. April 2024

Autophagy preserves hematopoietic stem cells by restraining MTORC1-mediated cellular anabolism.
Borsa, M. and Obba, S. and Richter, F.C. and Zhang, H. and Riffelmacher, T. and Carrelha, J. and Alsaleh, G. and Jacobsen, S.E.W. and Simon, A.K.
Autophagy 20 (1): 45-57. January 2024

2023

Proteostasis in T cell aging.
Gressler, A.E. and Leng, H. and Zinecker, H. and Simon, A.K.
Seminars in Immunology 70 : 101838. November 2023

Autophagy orchestrates the crosstalk between cells and organs.
Piletic, K. and Alsaleh, G. and Simon, A.K.
EMBO Reports 24 (9): e57289. 6 September 2023

The central role of DNA damage in immunosenescence.
Kell, L. and Simon, A.K. and Alsaleh, G. and Cox, L.S.
Frontiers in Aging 4 : 1202152. 3 July 2023

Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10.
Richter, F.C. and Friedrich, M. and Kampschulte, N. and Piletic, K. and Alsaleh, G. and Zummach, R. and Hecker, J. and Pohin, M. and Ilott, N. and Guschina, I. and Wideman, S.K. and Johnson, E. and Borsa, M. and Hahn, P. and Morriseau, C. and Hammock, B.D. and Schipper, H.S. and Edwards, C.M and Zechner, R. and Siegmund, B. and Weidinger, C. and Schebb, N.H. and Powrie, F. and Simon, A.K.
EMBO Journal 42 (6): e112202. 15 March 2023

2022

Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.
Leng, H. and Zhang, H. and Li, L. and Zhang, S. and Wang, Y. and Chavda, S.J. and Galas-Filipowicz, D. and Lou, H. and Ersek, A. and Morris, E.V. and Sezgin, E. and Lee, Y.H. and Li, Y. and Lechuga-Vieco, A.V. and Tian, M. and Mi, J.Q. and Yong, K. and Zhong, Q. and Edwards, C.M. and Simon, A.K. and Horwood, N.J.
Nature Communications 13 (1): 7868. 22 December 2022

Age-related mechanisms in the context of rheumatic disease.
Alsaleh, G. and Richter, F.C. and Simon, A.K.
Nature Reviews Rheumatology 18 (12): 694-710. December 2022

Mechanisms of spermidine-induced autophagy and geroprotection.
Hofer, S.J. and Simon, A.K. and Bergmann, M. and Eisenberg, T. and Kroemer, G. and Madeo, F.
Nature Aging 2 (12): 1112-1129. December 2022

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation.
Zhou, D. and Borsa, M. and Puleston, D.J. and Zellner, S. and Capera, J. and Sanderson, S. and Schifferer, M. and Hester, S.S. and Ge, X. and Fischer, R. and Jostins, L. and Behrends, C. and Alsaleh, G. and Simon, A.K.
Nature Communications 13 (1): 5174. 2 September 2022

GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao, Y. and Du Jiang, P. and Chao, B.N. and Cagdas, D. and Kubo, S. and Balasubramaniyam, A. and Zhang, Y. and Shadur, B. and NaserEddin, A. and Folio, L.R. and Schwarz, B. and Bohrnsen, E. and Zheng, L. and Lynberg, M. and Gottlieb, S. and Leney-Greene, M.A. and Park, A.Y. and Tezcan, I. and Akdogan, A. and Gocmen, R. and Onder, S. and Rosenberg, A. and Soilleux, E.J. and Johnson, E. and Jackson, P.K. and Demeter, J. and Chauvin, S.D. and Paul, F. and Selbach, M. and Bulut, H. and Clatworthy, M.R. and Tuong, Z.K. and Zhang, H. and Stewart, B.J. and Bosio, C.M. and Stepensky, P. and Clare, S. and Ganesan, S. and Pascall, J.C. and Daumke, O. and Butcher, G.W. and McMichael, A.J. and Simon, A.K. and Lenardo, M.J.
Journal of Experimental Medicine 219 (6): e20201405. 6 June 2022

Heteroplasmy of wild type mitochondrial DNA variants in mice causes metabolic heart disease with pulmonary hypertension and frailty.
Lechuga-Vieco, A.V. and Latorre-Pellicer, A. and Calvo, E. and Torroja, C. and Pellico, J. and Acín-Pérez, R. and García-Gil, M.L. and Santos, A. and Bagwan, N. and Bonzon-Kulichenko, E. and Magni, R. and Benito, M. and Justo-Méndez, R. and Simon, A.K. and Sánchez-Cabo, F. and Vázquez, J. and Ruíz-Cabello, J. and Enríquez, J.A.
Circulation 145 (12): 1084-1101. 5 April 2022

B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice.
Lee, M.S.J. and Inoue, T. and Ise, W. and Matsuo-Dapaah, J. and Wing, J.B. and Temizoz, B. and Kobiyama, K. and Hayashi, T. and Patil, A. and Sakaguchi, S. and Simon, A.K. and Bezbradica, J.S. and Nagatoishi, S. and Tsumoto, K. and Inoue, J.I. and Akira, S. and Kurosaki, T. and Ishii, K.J. and Coban, C.
Journal of Experimental Medicine 219 (2): e20211336. 7 February 2022

Autophagy takes it all - autophagy inducers target immune aging.
Zinecker, H. and Simon, A.K.
Disease Models & Mechanisms 15 (1): dmm049345. 31 January 2022

2021

Autophagy in major human diseases.
Klionsky, D.J. and Petroni, G. and Amaravadi, R.K. and Baehrecke, E.H. and Ballabio, A. and Boya, P. and Bravo-San Pedro, J.M. and Cadwell, K. and Cecconi, F. and Choi, A.M.K. and Choi, M.E. and Chu, C.T. and Codogno, P. and Colombo, M.I. and Cuervo, A.M. and Deretic, V. and Dikic, I. and Elazar, Z. and Eskelinen, E.L. and Fimia, G.M. and Gewirtz, D.A. and Green, D.R. and Hansen, M. and Jäättelä, M. and Johansen, T. and Juhász, G. and Karantza, V. and Kraft, C. and Kroemer, G. and Ktistakis, N.T. and Kumar, S. and Lopez-Otin, C. and Macleod, K.F. and Madeo, F. and Martinez, J. and Meléndez, A. and Mizushima, N. and Münz, C. and Penninger, J.M. and Perera, R.M. and Piacentini, M. and Reggiori, F. and Rubinsztein, D.C. and Ryan, K.M. and Sadoshima, J. and Santambrogio, L. and Scorrano, L. and Simon, H.U. and Simon, A.K. and Simonsen, A. and Stolz, A. and Tavernarakis, N. and Tooze, S.A. and Yoshimori, T. and Yuan, J. and Yue, Z. and Zhong, Q. and Galluzzi, L. and Pietrocola, F.
EMBO Journal 40 (19): e108863. 1 October 2021

Autophagy in healthy aging and disease.
Aman, Y. and Schmauck-Medina, T. and Hansen, M. and Morimoto, R.I. and Simon, A.K. and Bjedov, I. and Palikaras, K. and Simonsen, A. and Johansen, T. and Tavernarakis, N. and Rubinsztein, D.C. and Partridge, L. and Kroemer, G. and Labbadia, J. and Fang, E.F.
Nature Aging 1 (8): 634-650. 12 August 2021

EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells.
Roy, S. and Rizvi, Z.A. and Clarke, A.J. and Macdonald, F. and Pandey, A. and Zaiss, D.M.W. and Simon, A.K. and Awasthi, A.
Nature Communications 12 (1): 3182. 1 June 2021

Asymmetric cell division shapes naive and virtual memory T-cell immunity during ageing.
Borsa, M. and Barandun, N. and Gräbnitz, F. and Barnstorf, I. and Baumann, N.S. and Pallmer, K. and Baumann, S. and Stark, D. and Balaz, M. and Oetiker, N. and Wagen, F. and Wolfrum, C. and Simon, A.K. and Joller, N. and Barral, Y. and Spörri, R. and Oxenius, A.
Nature Communications 12 (1): 2715. 11 May 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Klionsky, D.J. and Abdel-Aziz, A.K. and Abdelfatah, S. and Abdellatif, M. and Abdoli, A. and Abel, S. and Abeliovich, H. and Abildgaard, M.H. and Abudu, Y.P. and Acevedo-Arozena, A. and Adamopoulos, I.E. and Adeli, K. and Adolph, T.E. and Adornetto, A. and Aflaki, E. and Agam, G. and Agarwal, A. and Aggarwal, B.B. and Agnello, M. and Agostinis, P. and Agrewala, J.N. and Agrotis, A. and Aguilar, P.V. and Ahmad, S.T. and Ahmed, Z.M. and Ahumada-Castro, U. and Aits, S. and Aizawa, S. and Akkoc, Y. and Akoumianaki, T. and Akpinar, H.A. and Al-Abd, A.M. and Al-Akra, L. and Al-Gharaibeh, A. and Alaoui-Jamali, M.A. and Alberti, S. and Alcocer-Gómez, E. and Alessandri, C. and Ali, M. and Alim Al-Bari, M.A. and Aliwaini, S. and Alizadeh, J. and Almacellas, E. and Almasan, A. and Alonso, A. and Alonso, G.D. and Altan-Bonnet, N. and Altieri, D.C. and Álvarez, E.M.C. and Alves, S. and Alves da Costa, C. and Alzaharna, M.M. and Amadio, M. and Amantini, C. and Amaral, C. and Ambrosio, S. and Amer, A.O. and Ammanathan, V. and An, Z. and Andersen, S.U. and Andrabi, S.A. and Andrade-Silva, M. and Andres, A.M. and Angelini, S. and Ann, D. and Anozie, U.C. and Ansari, M.Y. and Antas, P. and Antebi, A. and Antón, Z. and Anwar, T. and Apetoh, L. and Apostolova, N. and Araki, T. and Araki, Y. and Arasaki, K. and Araújo, W.L. and Araya, J. and Arden, C. and Arévalo, M.A. and Arguelles, S. and Arias, E. and Arikkath, J. and Arimoto, H. and Ariosa, A.R. and Armstrong-James, D. and Arnauné-Pelloquin, L. and Aroca, A. and Arroyo, D.S. and Arsov, I. and Artero, R. and Asaro, D.M.L. and Aschner, M. and Ashrafizadeh, M. and Ashur-Fabian, O. and Atanasov, A.G. and Au, A.K. and Auberger, P. and Auner, H.W. and Aurelian, L. and Autelli, R. and Avagliano, L. and Ávalos, Y. and Aveic, S. and Aveleira, C.A. and Avin-Wittenberg, T. and Aydin, Y. and Ayton, S. and Ayyadevara, S. and Azzopardi, M. and Baba, M.u and Backer, J.M. and Backues, S.K. and Bae, D.H. and Bae, O.N. and Bae, S.H. and Baehrecke, E.H. and Baek, A. and Baek, S.H. and Baek, S.H. and Bagetta, G. and Bagniewska-Zadworna, A. and Bai, H. and Bai, J. and Bai, X. and Bai, Y. and Bairagi, N. and Baksi, S. and Balbi, T. and Baldari, C.T. and Balduini, W. and Ballabio, A. and Ballester, M. and Balazadeh, S. and Balzan, R. and Bandopadhyay, R. and Banerjee, S. and Banerjee, S. and Bánréti, A. and Bao, Y. and Baptista, M.S. and Baracca, A. and Barbati, C. and Bargiela, A. and Barilà, D. and Barlow, P.G. and Barmada, S.J. and Barreiro, E. and Barreto, G.E. and Bartek, J. and Bartel, B. and Bartolome, A. and Barve, G.R. and Basagoudanavar, S.H. and Bassham, D.C. and Bast, R.C. and Basu, A. and Batoko, H. and Batten, I. and Baulieu, E.E. and Baumgarner, B.L. and Bayry, J. and Beale, R. and Beau, I. and Beaumatin, F. and Bechara, L.R.G. and Beck, G.R. and Beers, M.F. and Begun, J. and Behrends, C. and Behrens, G.M.N. and Bei, R. and Bejarano, E. and Bel, S. and Behl, C. and Belaid, A. and Belgareh-Touzé, N. and Bellarosa, C. and Belleudi, F. and Belló Pérez, M. and Bello-Morales, R. and Beltran, J.S.O. and Beltran, S. and Benbrook, D.M. and Bendorius, M. and Benitez, B.A. and Benito-Cuesta, I. and Bensalem, J. and Berchtold, M.W. and Berezowska, S. and Bergamaschi, D. and Bergami, M. and Bergmann, A. and Berliocchi, L. and Berlioz-Torrent, C. and Bernard, A. and Berthoux, L. and Besirli, C.G. and Besteiro, S. and Betin, V.M. and Beyaert, R. and Bezbradica, J.S. and Bhaskar, K. and Bhatia-Kissova, I. and Bhattacharya, R. and Bhattacharya, S. and Bhattacharyya, S. and Bhuiyan, M.S. and Bhutia, S.K. and Bi, L. and Bi, X. and Biden, T.J. and Bijian, K. and Billes, V.A. and Binart, N. and Bincoletto, C. and Birgisdottir, A.B. and Bjorkoy, G. and Blanco, G. and Blas-Garcia, A. and Blasiak, J. and Blomgran, R. and Blomgren, K. and Blum, J.S. and Boada-Romero, E. and Boban, M. and Boesze-Battaglia, K. and Boeuf, P. and Boland, B. and Bomont, P. and Bonaldo, P. and Bonam, S.R. and Bonfili, L. and Bonifacino, J.S. and Boone, B.A. and Bootman, M.D. and Bordi, M. and Borner, C. and Bornhauser, B.C. and Borthakur, G. and Bosch, J. and Bose, S. and Botana, L.M. and Botas, J. and Boulanger, C.M. and Boulton, M.E. and Bourdenx, M. and Bourgeois, B. and Bourke, N.M. and Bousquet, G. and Boya, P. and Bozhkov, P.V. and Bozi, L.H.M. and Bozkurt, T.O. and Brackney, D.E. and Brandts, C.H. and Braun, R.J. and Braus, G.H. and Bravo-Sagua, R. and Bravo-San Pedro, J.M. and Brest, P. and Bringer, M.A. and Briones-Herrera, A. and Broaddus, V.C. and Brodersen, P. and Brodsky, J.L. and Brody, S.L. and Bronson, P.G. and Bronstein, J.M. and Brown, C.N. and Brown, R.E. and Brum, P.C. and Brumell, J.H. and Brunetti-Pierri, N. and Bruno, D. and Bryson-Richardson, R.J. and Bucci, C. and Buchrieser, C. and Bueno, M. and Buitrago-Molina, L.E. and Buraschi, S. and Buch, S. and Buchan, J.R. and Buckingham, E.M. and Budak, H. and Budini, M. and Bultynck, G. and Burada, F. and Burgoyne, J.R. and Burón, M.I. and Bustos, V. and Büttner, S. and Butturini, E. and Byrd, A. and Cabas, I. and Cabrera-Benitez, S. and Cadwell, K. and Cai, J. and Cai, L. and Cai, Q. and Cairó, M. and Calbet, J.A. and Caldwell, G.A. and Caldwell, K.A. and Call, J.A. and Calvani, R. and Calvo, A.C. and Calvo-Rubio Barrera, M. and Camara, N.O. and Camonis, J.H. and Camougrand, N. and Campanella, M. and Campbell, E.M. and Campbell-Valois, F.X. and Campello, S. and Campesi, I. and Campos, J.C. and Camuzard, O. and Cancino, J. and Candido de Almeida, D. and Canesi, L. and Caniggia, I. and Canonico, B. and Cantí, C. and Cao, B. and Caraglia, M. and Caramés, B. and Carchman, E.H. and Cardenal-Muñoz, E. and Cardenas, C. and Cardenas, L. and Cardoso, S.M. and Carew, J.S. and Carle, G.F. and Carleton, G. and Carloni, S. and Carmona-Gutierrez, D. and Carneiro, L.A. and Carnevali, O. and Carosi, J.M. and Carra, S. and Carrier, A. and Carrier, L. and Carroll, B. and Carter, A.B. and Carvalho, A.N. and Casanova, M. and Casas, C. and Casas, J. and Cassioli, C. and Castillo, E.F. and Castillo, K. and Castillo-Lluva, S. and Castoldi, F. and Castori, M. and Castro, A.F. and Castro-Caldas, M. and Castro-Hernandez, J. and Castro-Obregon, S. and Catz, S.D. and Cavadas, C. and Cavaliere, F. and Cavallini, G. and Cavinato, M. and Cayuela, M.L. and Cebollada Rica, P. and Cecarini, V. and Cecconi, F. and Cechowska-Pasko, M. and Cenci, S. and Ceperuelo-Mallafré, V. and Cerqueira, J.J. and Cerutti, J.M. and Cervia, D. and Cetintas, V.B. and Cetrullo, S. and Chae, H.J. and Chagin, A.S. and Chai, C.Y. and Chakrabarti, G. and Chakrabarti, O. and Chakraborty, T. and Chakraborty, T. and Chami, M. and Chamilos, G. and Chan, D.W. and Chan, E.Y.W. and Chan, E.D. and Chan, H.Y.E. and Chan, H.H. and Chan, H. and Chan, M.T.V. and Chan, Y.S. and Chandra, P.K. and Chang, C.P. and Chang, C. and Chang, H.C. and Chang, K. and Chao, J. and Chapman, T. and Charlet-Berguerand, N. and Chatterjee, S. and Chaube, S.K. and Chaudhary, A. and Chauhan, S. and Chaum, E. and Checler, F. and Cheetham, M.E. and Chen, C.S. and Chen, G.C. and Chen, J.F. and Chen, L.L. and Chen, L. and Chen, L. and Chen, M. and Chen, M.K. and Chen, N. and Chen, Q. and Chen, R.H. and Chen, S. and Chen, W. and Chen, W. and Chen, X.M. and Chen, X.W. and Chen, X. and Chen, Y. and Chen, Y.G. and Chen, Y. and Chen, Y. and Chen, Y.J. and Chen, Y.Q. and Chen, Z.S. and Chen, Z. and Chen, Z.H. and Chen, Z.J. and Chen, Z. and Cheng, H. and Cheng, J. and Cheng, S.Y. and Cheng, W. and Cheng, X. and Cheng, X.T. and Cheng, Y. and Cheng, Z. and Chen, Z. and Cheong, H. and Cheong, J.K. and Chernyak, B.V. and Cherry, S. and Cheung, C.F.R. and Cheung, C.H.A. and Cheung, K.H. and Chevet, E. and Chi, R.J. and Chiang, A.K.S. and Chiaradonna, F. and Chiarelli, R. and Chiariello, M. and Chica, N. and Chiocca, S. and Chiong, M. and Chiou, S.H. and Chiramel, A.I. and Chiurchiù, V. and Cho, D.H. and Choe, S.K. and Choi, A.M.K. and Choi, M.E. and Choudhury, K.R. and Chow, N.S. and Chu, C.T. and Chua, J.P. and Chua, J.J.E. and Chung, H. and Chung, K.P. and Chung, S. and Chung, S.H. and Chung, Y.L. and Cianfanelli, V. and Ciechomska, I.A. and Cifuentes, M. and Cinque, L. and Cirak, S. and Cirone, M. and Clague, M.J. and Clarke, R. and Clementi, E. and Coccia, E.M. and Codogno, P. and Cohen, E. and Cohen, M.M and Colasanti, T. and Colasuonno, F. and Colbert, R.A. and Colell, A. and Čolić, M. and Coll, N.S. and Collins, M.O. and Colombo, M.I. and Colón-Ramos, D.A. and Combaret, L. and Comincini, S. and Cominetti, M.R. and Consiglio, A. and Conte, A. and Conti, F. and Contu, V.R. and Cookson, M.R. and Coombs, K.M. and Coppens, I. and Corasaniti, M.T. and Corkery, D.P. and Cordes, N. and Cortese, K. and Costa, M.D.C. and Costantino, S. and Costelli, P. and Coto-Montes, A. and Crack, P.J. and Crespo, J.L. and Criollo, A. and Crippa, V. and Cristofani, R. and Csizmadia, T. and Cuadrado, A. and Cui, B. and Cui, J. and Cui, Y. and Cui, Y. and Culetto, E. and Cumino, A.C. and Cybulsky, A.V. and Czaja, M.J. and Czuczwar, S.J. and D'Adamo, S. and D'Amelio, M. and D'Arcangelo, D. and D'Lugos, A.C. and D'Orazi, G. and da Silva, J.A. and Dafsari, H.S. and Dagda, R.K. and Dagdas, Y. and Daglia, M. and Dai, X. and Dai, Y. and Dai, Y. and Dal Col, J. and Dalhaimer, P. and Dalla Valle, L. and Dallenga, T. and Dalmasso, G. and Damme, M. and Dando, I. and Dantuma, N.P. and Darling, A.L. and Das, H. and Dasarathy, S. and Dasari, S.K. and Dash, S. and Daumke, O. and Dauphinee, A.N. and Davies, J.S. and Dávila, V.A. and Davis, R.J. and Davis, T. and Dayalan Naidu, S. and De Amicis, F. and De Bosscher, K. and De Felice, F. and De Franceschi, L. and De Leonibus, C. and de Mattos Barbosa, M.G. and De Meyer, G.R.Y. and De Milito, A. and De Nunzio, C. and De Palma, C. and De Santi, M. and De Virgilio, C. and De Zio, D. and Debnath, J. and DeBosch, B.J. and Decuypere, J.P. and Deehan, M.A. and Deflorian, G. and DeGregori, J. and Dehay, B. and Del Rio, G. and Delaney, J.R. and Delbridge, L.M.D. and Delorme-Axford, E. and Delpino, M.V. and Demarchi, F. and Dembitz, V. and Demers, N.D. and Deng, H. and Deng, Z. and Dengjel, J. and Dent, P. and Denton, D. and DePamphilis, M.L. and Der, C.J. and Deretic, V. and Descoteaux, A. and Devis, L. and Devkota, S. and Devuyst, O. and Dewson, G. and Dharmasivam, M. and Dhiman, R. and di Bernardo, D. and Di Cristina, M. and Di Domenico, F. and Di Fazio, P. and Di Fonzo, A. and Di Guardo, G. and Di Guglielmo, G.M. and Di Leo, L. and Di Malta, C. and Di Nardo, A. and Di Rienzo, M. and Di Sano, F. and Diallinas, G. and Diao, J. and Diaz-Araya, G. and Díaz-Laviada, I. and Dickinson, J.M. and Diederich, M. and Dieudé, M. and Dikic, I. and Ding, S. and Ding, W.X. and Dini, L. and Dinić, J. and Dinic, M. and Dinkova-Kostova, A.T. and Dionne, M.S. and Distler, J.H.W. and Diwan, A. and Dixon, I.M.C. and Djavaheri-Mergny, M. and Dobrinski, I. and Dobrovinskaya, O. and Dobrowolski, R. and Dobson, R.C.J. and Đokić, J. and Dokmeci Emre, S. and 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Zappavigna, S. and Zaragoza, P. and Zarbalis, K.S. and Zarebkohan, A. and Zarrouk, A. and Zeitlin, S.O. and Zeng, J. and Zeng, J.D. and Žerovnik, E. and Zhan, L. and Zhang, B. and Zhang, D.D. and Zhang, H. and Zhang, H. and Zhang, H. and Zhang, H. and Zhang, H. and Zhang, H. and Zhang, H. and Zhang, H.L. and Zhang, J. and Zhang, J. and Zhang, J.P. and Zhang, K.Y.B. and Zhang, L.W. and Zhang, L. and Zhang, L. and Zhang, L. and Zhang, L. and Zhang, M. and Zhang, P. and Zhang, S. and Zhang, W. and Zhang, X. and Zhang, X.W. and Zhang, X. and Zhang, X. and Zhang, X. and Zhang, X. and Zhang, X.D. and Zhang, Y. and Zhang, Y. and Zhang, Y. and Zhang, Y.D. and Zhang, Y. and Zhang, Y.Y. and Zhang, Y. and Zhang, Z. and Zhang, Z. and Zhang, Z. and Zhang, Z. and Zhang, Z. and Zhang, Z. and Zhao, H. and Zhao, L. and Zhao, S. and Zhao, T. and Zhao, X.F. and Zhao, Y. and Zhao, Y. and Zhao, Y. and Zhao, Y. and Zheng, G. and Zheng, K. and Zheng, L. and Zheng, S. and Zheng, X.L. and Zheng, Y. and Zheng, Z.G. and Zhivotovsky, B. and Zhong, Q. and Zhou, A. and Zhou, B. and Zhou, C. and Zhou, G. and Zhou, H. and Zhou, H. and Zhou, H. and Zhou, J. and Zhou, J. and Zhou, J. and Zhou, J. and Zhou, K. and Zhou, R. and Zhou, X.J. and Zhou, Y. and Zhou, Y. and Zhou, Y. and Zhou, Z.Y. and Zhou, Z. and Zhu, B. and Zhu, C. and Zhu, G.Q. and Zhu, H. and Zhu, H. and Zhu, H. and Zhu, W.G. and Zhu, Y. and Zhu, Y. and Zhuang, H. and Zhuang, X. and Zientara-Rytter, K. and Zimmermann, C.M. and Ziviani, E. and Zoladek, T. and Zong, W.X. and Zorov, D.B. and Zorzano, A. and Zou, W. and Zou, Z. and Zou, Z. and Zuryn, S. and Zwerschke, W. and Brand-Saberi, B. and Dong, X.C. and Kenchappa, C.S. and Li, Z. and Lin, Y. and Oshima, S. and Rong, Y. and Sluimer, J.C. and Stallings, C.L. and Tong, C.K.
Autophagy 17 (1): 1-382. 8 February 2021

Hallmarks and detection techniques of cellular senescence and cellular ageing in immune cells.
Zhou, D. and Borsa, M. and Simon, A.K.
Aging Cell 20 (2): e13316. 1 February 2021

The role and uses of antibodies in COVID-19 infections: a living review.
Scourfield, D.C. and Reed, S.G. and Quastel, M. and Alderson, J. and Bart, V.M.T. and Teijeira Crespo, A. and Jones, R. and Pring, E. and Richter, F.C. and Burnell, S.E.A.
Oxford Open Immunology 2 (1): iqab003. 28 January 2021

Regulating T-cell differentiation through the polyamine spermidine.
Carriche, G.M. and Almeida, L. and Stüve, P. and Velasquez, L. and Dhillon-LaBrooy, A. and Roy, U. and Lindenberg, M. and Strowig, T. and Plaza-Sirvent, C. and Schmitz, I. and Lochner, M. and Simon, A.K. and Sparwasser, T.
Journal of Allergy and Clinical Immunology 147 (1): 335-348. January 2021

2020

Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses.
Alsaleh, G. and Panse, I. and Swadling, L. and Zhang, H. and Richter, F.C. and Meyer, A. and Lord, J. and Barnes, E. and Klenerman, P. and Green, C. and Simon, A.K.
eLife 9 : e57950. 15 December 2020

Beth Levine 1960-2020.
Simon, A.K. and Mizushima, N.
Nature Cell Biology 22 (8): 909-910. August 2020

Fine-tuning stemness.
Borsa, M. and Simon, A.K.
Science 369 (6502): 373-374. 24 July 2020

Cortical cells are altered by factors including bone morphogenetic protein released from a placental barrier model under altered oxygenation.
Leinster, V.H.L. and Phillips, T.J. and Jones, N. and Sanderson, S. and Simon, K. and Hanley, J. and Case, C.P.
Neuronal Signaling 4 (1): NS20190148. April 2020

Human liver memory CD8(+) T cells use autophagy for tissue residence.
Swadling, L. and Pallett, L.J. and Diniz, M.O. and Baker, J.M. and Amin, O.E. and Stegmann, K.A. and Burton, A.R. and Schmidt, N.M. and Jeffery-Smith, A. and Zakeri, N. and Suveizdyte, K. and Froghi, F. and Fusai, G. and Rosenberg, W.M. and Davidson, B.R. and Schurich, A. and Simon, A.K. and Maini, M.K.
Cell Reports 30 (3): 687-698. 21 January 2020

Polyamines reverse immune senescence via the translational control of autophagy.
Zhang, H. and Simon, A.K.
Autophagy 16 (1): 181-182. January 2020

2019

Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence.
Zhang, H. and Alsaleh, G. and Feltham, J. and Sun, Y. and Napolitano, G. and Riffelmacher, T. and Charles, P. and Frau, L. and Hublitz, P. and Yu, Z. and Mohammed, S. and Ballabio, A. and Balabanov, S. and Mellor, J. and Simon, A.K.
Molecular Cell 76 (1): 110-125. 3 October 2019

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Cossarizza, A. and Chang, H.D. and Radbruch, A. and Acs, A. and Adam, D. and Adam-Klages, S. and Agace, W.W. and Aghaeepour, N. and Akdis, M. and Allez, M. and Almeida, L.N. and Alvisi, G. and Anderson, G. and Andrä, I. and Annunziato, F. and Anselmo, A. and Bacher, P. and Baldari, C.T. and Bari, S. and Barnaba, V. and Barros-Martins, J. and Battistini, L. and Bauer, W. and Baumgart, S. and Baumgarth, N. and Baumjohann, D. and Baying, B. and Bebawy, M. and Becher, B. and Beisker, W. and Benes, V. and Beyaert, R. and Blanco, A. and Boardman, D.A. and Bogdan, C. and Borger, J.G. and Borsellino, G. and Boulais, P.E. and Bradford, J.A. and Brenner, D. and Brinkman, R.R. and Brooks, A.E.S. and Busch, D.H. and Büscher, M. and Bushnell, T.P. and Calzetti, F. and Cameron, G. and Cammarata, I. and Cao, X. and Cardell, S.L. and Casola, S. and Cassatella, M.A. and Cavani, A. and Celada, A. and Chatenoud, L. and Chattopadhyay, P.K. and Chow, S. and Christakou, E. and Čičin-Šain, L. and Clerici, M. and Colombo, F.S. and Cook, L. and Cooke, A. and Cooper, A.M. and Corbett, A.J. and Cosma, A. and Cosmi, L. and Coulie, P.G. and Cumano, A. and Cvetkovic, L. and Dang, V.D. and Dang-Heine, C. and Davey, M.S. and Davies, D. and De Biasi, S. and Del Zotto, G. and Dela Cruz, G.V. and Delacher, M. and Della Bella, S. and Dellabona, P. and Deniz, G. and Dessing, M. and Di Santo, J.P. and Diefenbach, A. and Dieli, F. and Dolf, A. and Dörner, T. and Dress, R.J. and Dudziak, D. and Dustin, M. and Dutertre, C.A. and Ebner, F. and Eckle, S.B.G. and Edinger, M. and Eede, P. and Ehrhardt, G.R.A. and Eich, M. and Engel, P. and Engelhardt, B. and Erdei, A. and Esser, C. and Everts, B. and Evrard, M. and Falk, C.S. and Fehniger, T.A. and Felipo-Benavent, M. and Ferry, H. and Feuerer, M. and Filby, A. and Filkor, K. and Fillatreau, S. and Follo, M. and Förster, I. and Foster, J. and Foulds, G.A. and Frehse, B. and Frenette, P.S. and Frischbutter, S. and Fritzsche, W. and Galbraith, D.W. and Gangaev, A. and Garbi, N. and Gaudilliere, B. and Gazzinelli, R.T. and Geginat, J. and Gerner, W. and Gherardin, N.A. and Ghoreschi, K. and Gibellini, L. and Ginhoux, F. and Goda, K. and Godfrey, D.I. and Goettlinger, C. and González-Navajas, J.M. and Goodyear, C.S. and Gori, A. and Grogan, J.L. and Grummitt, D. and Grützkau, A. and Haftmann, C. and Hahn, J. and Hammad, H. and Hämmerling, G. and Hansmann, L. and Hansson, G. and Harpur, C.M. and Hartmann, S. and Hauser, A. and Hauser, A.E. and Haviland, D.L. and Hedley, D. and Hernández, D.C. and Herrera, G. and Herrmann, M. and Hess, C. and Höfer, T. and Hoffmann, P. and Hogquist, K. and Holland, T. and Höllt, T. and Holmdahl, R. and Hombrink, P. and Houston, J.P. and Hoyer, B.F. and Huang, B. and Huang, F.P. and Huber, J.E. and Huehn, J. and Hundemer, M. and Hunter, C.A. and Hwang, W.Y.K. and Iannone, A. and Ingelfinger, F. and Ivison, S.M. and Jäck, H.M. and Jani, P.K. and Jávega, B. and Jonjic, S. and Kaiser, T. and Kalina, T. and Kamradt, T. and Kaufmann, S.H.E. and Keller, B. and Ketelaars, S.L.C. and Khalilnezhad, A. and Khan, S. and Kisielow, J. and Klenerman, P. and Knopf, J. and Koay, H.F. and Kobow, K. and Kolls, J.K. and Kong, W.T. and Kopf, M. and Korn, T. and Kriegsmann, K. and Kristyanto, H. and Kroneis, T. and Krueger, A. and Kühne, J. and Kukat, C. and Kunkel, D. and Kunze-Schumacher, H. and Kurosaki, T. and Kurts, C. and Kvistborg, P. and Kwok, I. and Landry, J. and Lantz, O. and Lanuti, P. and LaRosa, F. and Lehuen, A. and LeibundGut-Landmann, S. and Leipold, M.D. and Leung, L.Y.T. and Levings, M.K. and Lino, A.C. and Liotta, F. and Litwin, V. and Liu, Y. and Ljunggren, H.G. and Lohoff, M. and Lombardi, G. and Lopez, L. and López-Botet, M. and Lovett-Racke, A.E. and Lubberts, E. and Luche, H. and Ludewig, B. and Lugli, E. and Lunemann, S. and Maecker, H.T. and Maggi, L. and Maguire, O. and Mair, Fl. and Mair, K.H. and Mantovani, A. and Manz, R.A. and Marshall, A.J. and Martínez-Romero, A. and Martrus, G. and Marventano, I. and Maslinski, W. and Matarese, G. and Mattioli, A.V. and Maueröder, C. and Mazzoni, A. and McCluskey, J. and McGrath, M. and McGuire, H.M. and McInnes, I.B. and Mei, H.E. and Melchers, F. and Melzer, S. and Mielenz, D. and Miller, S.D. and Mills, K.H.G. and Minderman, H. and Mjösberg, J. and Moore, J. and Moran, B. and Moretta, L. and Mosmann, T.R. and Müller, S. and Multhoff, G. and Muñoz, L.E. and Münz, C. and Nakayama, T. and Nasi, M. and Neumann, K. and Ng, L.G. and Niedobitek, A. and Nourshargh, S. and Núñez, G. and O'Connor, J.E. and Ochel, A. and Oja, A. and Ordonez, D. and Orfao, A. and Orlowski-Oliver, E. and Ouyang, W. and Oxenius, A. and Palankar, R. and Panse, I. and Pattanapanyasat, K. and Paulsen, M. and Pavlinic, D. and Penter, L. and Peterson, P. and Peth, C. and Petriz, J. and Piancone, F. and Pickl, W.F. and Piconese, S. and Pinti, M. and Pockley, A.G. and Podolska, M.J. and Poon, Z. and Pracht, K. and Prinz, I. and Pucillo, C.E.M. and Quataert, S.A. and Quatrini, L. and Quinn, K.M. and Radbruch, H. and Radstake, T.R.D.J. and Rahmig, S. and Rahn, H.P. and Rajwa, B. and Ravichandran, G. and Raz, Y. and Rebhahn, J.A. and Recktenwald, D. and Reimer, D. and Reis E Sousa, C. and Remmerswaal, E.B.M. and Richter, L. and Rico, L.G. and Riddell, A. and Rieger, A.M. and Robinson, J.P and Romagnani, C. and Rubartelli, A. and Ruland, J. and Saalmüller, A. and Saeys, Y. and Saito, T. and Sakaguchi, S. and Sala-de-Oyanguren, F. and Samstag, Y. and Sanderson, S. and Sandrock, I. and Santoni, A. and Sanz, R.B. and Saresella, M. and Sautes-Fridman, C. and Sawitzki, B. and Schadt, L. and Scheffold, A. and Scherer, H.U and Schiemann, M. and Schildberg, F.A. and Schimisky, E. and Schlitzer, A. and Schlosser, J. and Schmid, S. and Schmitt, S. and Schober, K. and Schraivogel, D. and Schuh, W. and Schüler, T. and Schulte, R. and Schulz, A.R. and Schulz, S.R. and Scottá, C. and Scott-Algara, D. and Sester, D.P. and Shankey, T.V. and Silva-Santos, B. and Simon, A.K. and Sitnik, K.M. and Sozzani, S. and Speiser, D.E. and Spidlen, J. and Stahlberg, A. and Stall, A.M. and Stanley, N. and Stark, R. and Stehle, C. and Steinmetz, T. and Stockinger, H. and Takahama, Y. and Takeda, K. and Tan, L. and Tárnok, A. and Tiegs, G. and Toldi, G. and Tornack, J. and Traggiai, E. and Trebak, M. and Tree, T.I.M. and Trotter, J. and Trowsdale, J. and Tsoumakidou, M. and Ulrich, H. and Urbanczyk, S. and van de Veen, W. and van den Broek, M. and van der Pol, E. and Van Gassen, S. and Van Isterdael, G. and van Lier, R.A.W. and Veldhoen, M. and Vento-Asturias, S. and Vieira, P. and Voehringer, D. and Volk, H.D. and von Borstel, A. and von Volkmann, K. and Waisman, A. and Walker, R.V. and Wallace, P.K. and Wang, S.A. and Wang, X.M. and Ward, M.D. and Ward-Hartstonge, K.A. and Warnatz, K. and Warnes, G. and Warth, S. and Waskow, C. and Watson, J.V. and Watzl, C. and Wegener, L. and Weisenburger, T. and Wiedemann, A. and Wienands, J. and Wilharm, A. and Wilkinson, R.J. and Willimsky, G. and Wing, J.B. and Winkelmann, R. and Winkler, T.H. and Wirz, O.F. and Wong, A. and Wurst, P. and Yang, J.H.M. and Yang, J. and Yazdanbakhsh, M. and Yu, L. and Yue, A. and Zhang, H. and Zhao, Y. and Ziegler, S.M. and Zielinski, C. and Zimmermann, J. and Zychlinsky, A.
European Journal of Immunology 49 (10): 1457-1973. October 2019

Insights into pancreatic β cell energy metabolism using rodent β cell models.
Morten, K.J. and Potter, M. and Badder, L. and Sivathondan, P. and Dragovic, R. and Neumann, A. and Gavin, J. and Shrestha, R. and Reilly, S. and Phadwal, K. and Lodge, T.A. and Borzychowski, A. and Cookson, S. and Mitchell, C. and Morovat, A. and Simon, A.K. and Uusimaa, J. and Hynes, J. and Poulton, J.
Wellcome Open Research 2 : 14. 25 September 2019

Autophagy in the renewal, differentiation and homeostasis of immune cells.
Clarke, A.J. and Simon, A.K.
Nature Reviews Immunology 19 (3): 170-183. March 2019

2018

Local exchange of metabolites shapes immunity.
Richter, F.C. and Obba, S. and Simon, A.K.
Immunology 155 (3): 309-319. November 2018

A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation.
Breglio, K.F. and Amato, R. and Eastman, R. and Lim, P. and Sa, J.M. and Guha, R. and Ganesan, S. and Dorward, D.W. and Klumpp-Thomas, C. and McKnight, C. and Fairhurst, R.M. and Roberts, D. and Thomas, C. and Simon, A.K.
Malaria Journal 17 (1): 391. 26 October 2018

Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells.
Smith, A.M. and Depp, C. and Ryan, B.J. and Johnston, G.I. and Alegre-Abarrategui, J. and Evetts, S. and Rolinski, M. and Baig, F. and Ruffmann, C. and Simon, A.K. and Hu, M.T.M. and Wade-Martins, R.
Movement Disorders 33 (10): 1580-1590. October 2018

B1a B cells require autophagy for metabolic homeostasis and self-renewal.
Clarke, A.J. and Riffelmacher, T. and Braas, D. and Cornall, R.J. and Simon, A.K.
Journal of Experimental Medicine 215 (2): 399-413. 5 February 2018

Autophagy dictates metabolism and differentiation of inflammatory immune cells.
Riffelmacher, T. and Richter, F.C. and Simon, A.K.
Autophagy 14 (2): 199-206. 2018

2017

In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay.
Sanderson, S.L. and Simon, A.K.
Aging Cell 16 (6): 1234-1243. December 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (first edition).
Cossarizza, A. and Chang, H.D. and Radbruch, A. and Akdis, M. and Andrä, I. and Annunziato, F. and Bacher, P. and Barnaba, V. and Battistini, L. and Bauer, W.M. and Baumgart, S. and Becher, B. and Beisker, W. and Berek, C. and Blanco, A. and Borsellino, G. and Boulais, P.E. and Brinkman, R.R. and Büscher, M. and Busch, D.H. and Bushnell, T.P. and Cao, X. and Cavani, A. and Chattopadhyay, P.K. and Cheng, Q. and Chow, S. and Clerici, M. and Cooke, A. and Cosma, A. and Cosmi, L. and Cumano, A. and Dang, V.D. and Davies, D. and De Biasi, S. and Del Zotto, G. and Della Bella, S. and Dellabona, P. and Deniz, G. and Dessing, M. and Diefenbach, A. and Di Santo, J. and Dieli, F. and Dolf, A. and Donnenberg, V.S. and Dörner, T. and Ehrhardt, G.R.A. and Endl, E. and Engel, P. and Engelhardt, B. and Esser, C. and Everts, B. and Dreher, A. and Falk, C.S. and Fehniger, T.A. and Filby, A. and Fillatreau, S. and Follo, M. and Förster, I. and Foster, J. and Foulds, G.A. and Frenette, P.S. and Galbraith, D. and Garbi, N. and García-Godoy, M.D. and Geginat, J. and Ghoreschi, K. and Gibellini, L. and Goettlinger, C. and Goodyear, C.S. and Gori, A. and Grogan, J. and Gross, M. and Grützkau, A. and Grummitt, D. and Hahn, J. and Hammer, Q. and Hauser, A.E. and Haviland, D.L. and Hedley, D. and Herrera, G. and Herrmann, M. and Hiepe, F. and Holland, T. and Hombrink, P. and Houston, J.P. and Hoyer, B.F. and Huang, B. and Hunter, C.A. and Iannone, A. and Jäck, H.M. and Jávega, B. and Jonjic, S. and Juelke, K. and Jung, S. and Kaiser, T. and Kalina, T. and Keller, B. and Khan, S. and Kienhöfer, D. and Kroneis, T. and Kunkel, D. and Kurts, C. and Kvistborg, P. and Lannigan, J. and Lantz, O. and Larbi, A. and LeibundGut-Landmann, S. and Leipold, M.D. and Levings, M.K. and Litwin, V. and Liu, Y. and Lohoff, M. and Lombardi, G. and Lopez, L. and Lovett-Racke, A. and Lubberts, E. and Ludewig, B. and Lugli, E. and Maecker, H.T. and Martrus, G. and Matarese, G. and Maueröder, C. and McGrath, M. and McInnes, I. and Mei, H.E. and Melchers, F. and Melzer, S. and Mielenz, D. and Mills, K. and Mirrer, D. and Mjösberg, J. and Moore, J. and Moran, B. and Moretta, A. and Moretta, L. and Mosmann, T.R. and Müller, S. and Müller, W. and Münz, C. and Multhoff, G. and Munoz, L.E. and Murphy, K.M. and Nakayama, T. and Nasi, M. and Neudörfl, C. and Nolan, J. and Nourshargh, S. and O'Connor, J.E. and Ouyang, W. and Oxenius, A. and Palankar, R. and Panse, I. and Peterson, P. and Peth, C. and Petriz, J. and Philips, D. and Pickl, W. and Piconese, S. and Pinti, M. and Pockley, A.G. and Podolska, M.J. and Pucillo, C. and Quataert, S.A. and Radstake, T.R.D.J. and Rajwa, B. and Rebhahn, J.A. and Recktenwald, D. and Remmerswaal, E.B.M. and Rezvani, K. and Rico, L.G. and Robinson, J.P. and Romagnani, C. and Rubartelli, A. and Ruckert, B. and Ruland, J. and Sakaguchi, S. and Sala-de-Oyanguren, F. and Samstag, Y. and Sanderson, S. and Sawitzki, B. and Scheffold, A. and Schiemann, M. and Schildberg, F. and Schimisky, E. and Schmid, S.A. and Schmitt, S. and Schober, K. and Schüler, T. and Schulz, A.R. and Schumacher, T. and Scotta, C. and Shankey, T.V. and Shemer, A. and Simon, A.K. and Spidlen, J. and Stall, A.M. and Stark, R. and Stehle, C. and Stein, M. and Steinmetz, T. and Stockinger, H. and Takahama, Y. and Tarnok, A. and Tian, Z.G. and Toldi, G. and Tornack, J. and Traggiai, E. and Trotter, J. and Ulrich, H. and van der Braber, M. and van Lier, R.A.W. and Veldhoen, M. and Vento-Asturias, S. and Vieira, P. and Voehringer, D. and Volk, H.D. and von Volkmann, K. and Waisman, A. and Walker, R. and Ward, M.D. and Warnatz, K. and Warth, S. and Watson, J.V. and Watzl, C. and Wegener, L. and Wiedemann, A. and Wienands, J. and Willimsky, G. and Wing, J. and Wurst, P. and Yu, L. and Yue, A. and Zhang, Q. and Zhao, Y. and Ziegler, S. and Zimmermann, J.
European Journal of Immunology 47 (10): 1584-1797. 11 October 2017

Autophagy-dependent generation of free fatty acids is critical for normal neutrophil differentiation.
Riffelmacher, T. and Clarke, A. and Richter, F.C. and Stranks, A. and Pandey, S. and Danielli, S. and Hublitz, P. and Yu, Z. and Johnson, E. and Schwerd, T. and McCullagh, J. and Uhlig, H. and Jacobsen, S.E.W. and Simon, A.K.
Immunity 47 (3): 466-480.e5. 19 September 2017

Molecular definitions of autophagy and related processes.
Galluzzi, L. and Baehrecke, E.H. and Ballabio, A. and Boya, P. and Bravo-San Pedro, J.M. and Cecconi, F. and Choi, A.M. and Chu, C.T. and Codogno, P. and Colombo, M.I. and Cuervo, A.M. and Debnath, J. and Deretic, V. and Dikic, I. and Eskelinen, E.L. and Fimia, G.M. and Fulda, S. and Gewirtz, D.A. and Green, D.R. and Hansen, M. and Harper, J.W. and Jäättelä, M. and Johansen, T. and Juhasz, G. and Kimmelman, A.C. and Kraft, C. and Ktistakis, N.T. and Kumar, S. and Levine, B. and Lopez-Otin, C. and Madeo, F. and Martens, S. and Martinez, J. and Melendez, A. and Mizushima, N. and Münz, C. and Murphy, L.O. and Penninger, J.M. and Piacentini, M. and Reggiori, F. and Rubinsztein, D.C. and Ryan, K.M. and Santambrogio, L. and Scorrano, L. and Simon, A.K. and Simon, H.U. and Simonsen, A. and Tavernarakis, N. and Tooze, S.A. and Yoshimori, T. and Yuan, J. and Yue, Z. and Zhong, Q. and Kroemer, G.
EMBO Journal 36 (13): 1811-1836. 3 July 2017

Mechanistic roles of autophagy in hematopoietic differentiation.
Riffelmacher, T. and Simon, A.K.
FEBS Journal 284 (7): 1008-1020. April 2017

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.
Liao, C. and Ashley, N. and Diot, A. and Morten, K. and Phadwal, K. and Williams, A. and Fearnley, I. and Rosser, L. and Lowndes, J. and Fratter, C. and Ferguson, D.J.P. and Vay, L. and Quaghebeur, G. and Moroni, I. and Bianchi, S. and Lamperti, C. and Downes, S.M. and Sitarz, K.S. and Flannery, P.J. and Carver, J. and Dombi, E. and East, D. and Laura, M. and Reilly, M.M. and Mortiboys, H. and Prevo, R. and Campanella, M. and Daniels, M.J. and Zeviani, M. and Yu-Wai-Man, P. and Simon, A.K. and Votruba, M. and Poulton, J.
Neurology 88 (2): 131-142. 10 January 2017

2016

Exposure to zidovudine adversely affects mitochondrial turnover in primary T cells.
Wallace, Z.R. and Sanderson, S. and Simon, A.K. and Dorrell, L.
Antiviral Research 133 : 178-82. September 2016

Autophagy in T and B lymphocytes.
Clarke, A.J. and Simon, A.K.
Autophagy Networks in Inflammation : 171-184. 25 August 2016

Autophagy and immune senescence.
Zhang, H. and Puleston, D.J. and Simon, A.K.
Trends in Molecular Medicine 22 (8): 671-686. August 2016

Non-canonical autophagy LAPs lupus.
Simon, A.K. and Clarke, A.J.
Cell Death and Differentiation 23 (8): 1267-8. August 2016

The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.
Kabat, A.M. and Harrison, O.J. and Riffelmacher, T. and Moghaddam, A.E. and Pearson, C.F. and Laing, A. and Abeler-Dörner, L. and Forman, S.P. and Grencis, R.K. and Sattentau, Q. and Simon, A.K. and Pott, J. and Maloy, K.J.
eLife 5 : e12444. 11 March 2016

2015

Evolution of the immune system in humans from infancy to old age.
Simon, A.K. and Hollander, G.A. and McMichael, A.
Proceedings of the Royal Society of London Series B-Biological Sciences 282 (1821): 20143085. 22 December 2015

Current questions and possible controversies in autophagy.
Lindqvist, L.M. and Simon, A.K. and Baehrecke, E.H.
Cell Death Discovery 1 : 15036. 9 November 2015

Techniques for the detection of autophagy in primary mammalian cells.
Puleston, D. and Phadwal, K. and Watson, A.S. and Soilleux, E.J. and Chittaranjan, S. and Bortnik, S. and Gorski, S.M. and Ktistakis, N. and Simon, A.K.
Cold Spring Harbor Protocols 2015 (9): pdb.top070391. 1 September 2015

Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia.
Watson, A.S. and Riffelmacher, T. and Stranks, A. and Williams, O. and De Boer, J. and Cain, K. and MacFarlane, M. and McGouran, J. and Kessler, B. and Khandwala, S. and Chowdhury, O. and Puleston, D. and Phadwal, K. and Mortensen, M. and Ferguson, D. and Soilleux, E. and Woll, P. and Jacobsen, S.E.W. and Simon, A.K.
Cell Death Discovery 1 : 15008. 17 August 2015

Autophagy controls acquisition of aging features in macrophages.
Stranks, A.J. and Hansen, A.L. and Panse, I. and Mortensen, M. and Ferguson, D.J.P. and Puleston, D.J. and Shenderov, K. and Watson, A.S. and Veldhoen, M. and Phadwal, K. and Cerundolo, V. and Simon, A.K.
Journal of Innate Immunity 7 (4): 375-391. June 2015

Autophagy is activated in systemic lupus erythematosus and required for plasmablast development.
Clarke, A.J. and Ellinghaus, U. and Cortini, A. and Stranks, A. and Simon, A.K. and Botto, M. and Vyse, T.J.
Annals of the Rheumatic Diseases 74 (5): 912-20. May 2015

New roles for autophagy and spermidine in T cells.
Puleston, D.J. and Simon, A.K.
Microbial Cell 2 (3): 91-93. March 2015

An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease.
Pienaar, I.S. and Harrison, I.F. and Elson, J.L. and Bury, A. and Woll, P. and Simon, A.K. and Dexter, D.T.
Brain Structure & Function 220 (1): 479-500. January 2015

Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.
Jabir, M.S. and Hopkins, L. and Ritchie, N.D. and Ullah, I. and Bayes, H.K. and Li, D. and Tourlomousis, P. and Lupton, A. and Puleston, D. and Simon, A.K. and Bryant, C. and Evans, T.J.
Autophagy 11 (1): 166-182. 2015

2014

Essential role for autophagy during invariant NKT cell development.
Salio, M. and Puleston, D.J. and Mathan, T.S.M. and Shepherd, D. and Stranks, A.J. and Adamopoulou, E. and Veerapen, N. and Besra, G.S. and Hollander, G.A. and Simon, A.K. and Cerundolo, V.
Proceedings of the National Academy of Sciences of the United States of America 111 (52): E5678-E5687. 30 December 2014

Dual proteolytic pathways govern glycolysis and immune competence.
Lu, W. and Zhang, Y. and McDonald, D.O. and Jing, H. and Carroll, B. and Robertson, N. and Zhang, Q. and Griffin, H. and Sanderson, S. and Lakey, J.H. and Morgan, N.V. and Reynard, L.N. and Zheng, L. and Murdock, H.M. and Turvey, S.E. and Hackett, S.J. and Prestidge, T. and Hall, J.M. and Cant, A.J. and Matthews, H.F. and Koref, M.F.S. and Simon, A.K. and Korolchuk, V.I. and Lenardo, M.J. and Hambleton, S. and Su, H.C.
Cell 159 (7): 1578-1590. 18 December 2014

Autophagy is a critical regulator of memory CD8(+) T cell formation.
Puleston, D.J. and Zhang, H. and Powell, T.J. and Lipina, E. and Sims, S. and Panse, I. and Watson, A.S. and Cerundolo, V. and Townsend, A.R. and Klenerman, P. and Simon, A.K.
eLife 3 : e03706. 11 November 2014

Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions.
Curtis, D.J. and Sood, A. and Phillips, T.J. and Leinster, V.H.L. and Nishiguchi, A. and Coyle, C. and Lacharme-Lora, L. and Beaumont, O. and Kemp, H. and Goodall, R. and Cornes, L. and Giugliano, M. and Barone, R.A. and Matsusaki, M. and Akashi, M. and Tanaka, H.Y. and Kano, M. and McGarvey, J. and Halemani, N.D. and Simon, K. and Keehan, R. and Ind, W. and Masters, T. and Grant, S. and Athwal, S. and Collett, G. and Tannetta, D. and Sargent, I.L. and Scull-Brown, E. and Liu, X. and Aquilina, K. and Cohen, N. and Lane, J.D. and Thoresen, M. and Hanley, J. and Randall, A. and Case, C.P.
Experimental Neurology 261 : 386-395. November 2014

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8(+) T cells.
Henson, S.M. and Lanna, A. and Riddell, N.E. and Franzese, O. and Macaulay, R. and Griffiths, S.J. and Puleston, D.J. and Watson, A.S. and Simon, A.K. and Tooze, S.A. and Akbar, A.N.
Journal of Clinical Investigation 124 (9): 4004-4016. 2 September 2014

Caspase-1 cleavage of the TLR adaptor TRIF inhibits autophagy and β-interferon production during Pseudomonas aeruginosa infection.
Jabir, M.S. and Ritchie, N.D. and Li, D. and Bayes, H.K. and Tourlomousis, P. and Puleston, D. and Lupton, A. and Hopkins, L. and Simon, A.K. and Bryant, C. and Evans, T.J.
Cell Host & Microbe 15 (2): 214-227. 12 February 2014

Autophagy in the immune system.
Puleston, D.J. and Simon, A.K.
Immunology 141 (1): 1-8. January 2014

This list was generated on Mon May 20 02:19:55 2024 CEST.
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