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2018

CAR T cells with enhanced sensitivity to B cell maturation antigen for the targeting of B cell non-Hodgkin's lymphoma and multiple myeloma.
Bluhm, J. and Kieback, E. and Marino, S.F. and Oden, F. and Westermann, J. and Chmielewski, M. and Abken, H. and Uckert, W. and Höpken, U.E. and Rehm, A.
Molecular Therapy 26 (8): 1906-1920. 1 August 2018

2017

The splenic marginal zone shapes the phenotype of leukemia B cells and facilitates their niche-specific retention and survival.
Stache, V. and Verlaat, L. and Gätjen, M. and Heinig, K. and Westermann, J. and Rehm, A. and Höpken, U.E.
OncoImmunology 6 (6): e1323155. 6 June 2017

Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy.
Pahle, J. and Menzel, L. and Niesler, N. and Kobelt, D. and Aumann, J. and Rivera, M. and Walther, W.
BMC Cancer 17 (1): 129. 13 February 2017

Targeting HDAC3 in CREBBP-mutant lymphomas counterstrikes unopposed enhancer deacetylation of B-cell signaling and immune response genes.
Hoepken, U.E.
Cancer Discovery 7 (1): 14-16. January 2017

2016

Splenic marginal zone granulocytes acquire an accentuated neutrophil B cell-helper phenotype in chronic lymphocytic leukemia.
Gätjen, M. and Brand, F. and Grau, M. and Gerlach, K. and Kettritz, R. and Westermann, J. and Anagnostopoulos, I. and Lenz, P. and Lenz, G. and Höpken, U.E. and Rehm, A.
Cancer Research 76 (18): 5253-5265. 15 September 2016

The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6.
Stauss, D. and Brunner, C. and Berberich-Siebelt, F. and Höpken, U.E. and Lipp, M. and Müller, G.
EMBO Journal 35 (8): 881-898. 15 April 2016

Dysregulated development of IL-17-and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORγt.
Wichner, K. and Stauss, D. and Kampfrath, B. and Krüger, K. and Müller, G. and Rehm, A. and Lipp, M. and Höpken, U.E.
FASEB Journal 30 (2): 761-774. February 2016

2015

Loss of Gadkin affects dendritic cell migration in vitro.
Schachtner, H. and Weimershaus, M. and Stache, V. and Plewa, N. and Legler, D.F. and Höpken, U.E. and Maritzen, T.
PLoS ONE 10 (12): e0143883. 1 December 2015

Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Oden, F. and Marino, S.F. and Brand, J. and Scheu, S. and Kriegel, C. and Olal, D. and Takvorian, A. and Westermann, J. and Yilmaz, B. and Hinz, M. and Daumke, O. and Höpken, U.E. and Müller, G. and Lipp, M.
Molecular Oncology 9 (7): 1348-1358. August 2015

B cell localization and migration in health and disease.
Hauser, A.E. and Hoepken, U.E.
In: Molecular Biology of B Cells. UNSPECIFIED, 187-214. ISBN 978-0-12-397933-9 2015

2014

Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation.
Heinig, K. and Gätjen, M. and Grau, M. and Stache, V. and Anagnostopoulos, I. and Gerlach, K. and Niesner, R.A. and Cseresnyes, Z. and Hauser, A.E. and Lenz, P. and Hehlgans, T. and Brink, R. and Westermann, J. and Dörken, B. and Lipp, M. and Lenz, G. and Rehm, A. and Höpken, U.E.
Cancer Discovery 4 : 1448-1465. December 2014

Lymphotoxin-α keeps the gate open for T-cell infiltration in cHL.
Hoepken, U.E.
Blood 124 (19): 2897-2898. 6 November 2014

Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ.
Rehm, A. and Gätjen, M. and Gerlach, K. and Scholz, F. and Mensen, A. and Gloger, M. and Heinig, K. and Lamprecht, B. and Mathas, S. and Bégay, V. and Leutz, A. and Lipp, M. and Dörken, B. and Höpken, U.E.
Nature Communications 5 : 5057. 30 September 2014

B-cell-intrinsic STAT6 signaling controls germinal center formation.
Turqueti-Neves, A. and Otte, M. and da Costa, O.P. and Höpken, U.E. and Lipp, M. and Buch, T. and Voehringer, D.
European Journal of Immunology 44 (7): 2130-2138. July 2014

Increased levels of CCR7 ligands in carotid atherosclerosis: different effects in macrophages and smooth muscle cells.
Halvorsen, B. and Dahl, T.B. and Smedbakken, L.M. and Singh, A. and Michelsen, A.E. and Skjelland, M. and Krohg-Sørensen, K. and Russell, D. and Höpken, U.E. and Lipp, M. and Damås, J.K. and Holm, S. and Yndestad, A. and Biessen, E.A. and Aukrust, P.
Cardiovascular Research 102 (1): 148-156. 1 April 2014

2013

Transition from an autoimmune-prone state to fatal autoimmune disease in CCR7 and RORγt double-deficient mice is dependent on gut microbiota.
Wichner, K. and Fischer, A. and Winter, S. and Tetzlaff, S. and Heimesaat, M.M. and Bereswill, S. and Rehm, A. and Lipp, M. and Höpken, U.E.
Journal of Autoimmunity 47 : 58-72. December 2013

2012

The sorting receptor sortilin exhibits a dual function in exocytic trafficking of interferon-γ and granzyme A in T cells.
Herda, S. and Raczkowski, F. and Mittruecker, H.W. and Willimsky, G. and Gerlach, K. and Kuehl, A.A. and Breiderhoff, T. and Willnow, T.E. and Doerken, B. and Hoepken, U.E. and Rehm, A.
Immunity 37 (5): 854-866. 16 November 2012

Homeostatic chemokines guide lymphoma cells to tumor growth-promoting niches within secondary lymphoid organs.
Hoepken, U.E. and Rehm, A.
Journal of Molecular Medicine 90 (11): 1237-1245. November 2012

CCR7 deficiency causes diarrhea associated with altered ion transport in colonocytes in the absence of overt colitis.
Schumann, M. and Winter, S. and Wichner, K. and May, C. and Kuehl, A.A. and Batra, A. and Siegmund, B. and Zeitz, M. and Schulzke, J.D. and Lipp, M. and Hoepken, U.E.
Mucosal Immunology 5 (4): 377-387. July 2012

2011

Manifestation of spontaneous and early autoimmune gastritis in CCR7-deficient mice.
Winter, S. and Rehm, A. and Wichner, K. and Scheel, T. and Batra, A. and Siegmund, B. and Berek, C. and Lipp, M. and Hoepken, U.E.
American Journal of Pathology 179 (2): 754-765. August 2011

Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs.
Rehm, A. and Mensen, A. and Schradi, K. and Gerlach, K. and Wittstock, S. and Winter, S. and Buechner, G. and Doerken, B. and Lipp, M. and Hoepken, U.E.
Blood 118 (4): 1020-1033. 28 July 2011

2010

The chemokine receptor CXCR5 is pivotal for ectopic mucosa-associated lymphoid tissue neogenesis in chronic Helicobacter pylori-induced inflammation.
Winter, S. and Loddenkemper, C. and Aebischer, A. and Raebel, K. and Hoffmann, K. and Meyer, T.F. and Lipp, M. and Hoepken, U.E.
Journal of Molecular Medicine 88 (11): 1169-1180. November 2010

CCR7 regulates lymphocyte egress and recirculation through body cavities.
Hoepken, U.E. and Winter, S. and Achtman, A.H. and Krueger, K. and Lipp, M.
Journal of Leukocyte Biology 87 (4): 671-682. April 2010

2009

Identification of a chemokine receptor profile characteristic for mediastinal large B-cell lymphoma.
Rehm, A. and Anagnostopoulos, I. and Gerlach, K. and Broemer, M. and Scheidereit, C. and Joehrens, K. and Huebler, M. and Hetzer, R. and Stein, H. and Lipp, M. and Doerken, B. and Hoepken, U.E.
International Journal of Cancer 125 (10): 2367-2374. 15 November 2009

Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation.
van de Pavert, S.A. and Olivier, B.J. and Goverse, G. and Vondenhoff, M.F. and Greuter, M. and Beke, P. and Kusser, K. and Hoepken, U.E. and Lipp, M. and Niederreither, K. and Blomhoff, R. and Sitnik, K. and Agace, W.W. and Randall, T.D. and de Jonge, W.J. and Mebius, R.E.
Nature Immunology 10 (11): 1193-1199. November 2009

The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells.
Rueder, C. and Hoepken, U.E. and Wolf, J. and Mittruecker, H.W. and Engels, B. and Erdmann, B. and Wollenzin, S. and Uckert, W. and Doerken, B. and Rehm, A.
Journal of Clinical Investigation 119 (8): 2184-2203. August 2009

Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE.
van Zwam, M. and Huizinga, R. and Melief, M.J. and Wierenga-Wolf, A.F. and van Meurs, M. and Voerman, J.S. and Biber, K.P. and Boddeke, H.W. and Hoepken, U.E. and Meisel, C. and Meisel, A. and Bechmann, I. and Hintzen, R.Q. and 't Hart, B.A. and Amor, S. and Laman, J.D. and Boven, L.A.
Journal of Molecular Medicine 87 (3): 273-286. March 2009

CCR7-deficient mice develop atypically persistent germinal centers in response to thymus-independent type 2 antigens.
Achtman, A.H. and Hoepken, U.E. and Bernert, C. and Lipp, M.
Journal of Leukocyte Biology 85 (3): 409-417. March 2009

2007

CXCR5- and CCR7-dependent lymphoid neogenesis in a murine model of chronic antigen-induced arthritis.
Wengner, A.M. and Hoepken, U.E. and Petrow, P.K. and Hartmann, S. and Schurigt, U. and Braeuer, R. and Lipp, M.
Arthritis and Rheumatism 56 (10): 3271-3283. October 2007

CCL19 (ELC) as an adjuvant for DNA vaccination: induction of a TH1-type T-cell response and enhancement of antitumor immunity.
Westermann, J. and Nguyen-Hoai, T. and Baldenhofer, G. and Hoepken, U.E. and Lipp, M. and Doerken, B. and Pezzutto, A.
Cancer Gene Therapy 14 (6): 523-532. June 2007

Distinctive role of CCR7 in migration and functional activity of naive- and effector/memory-like Treg subsets.
Menning, A. and Hoepken, U.E. and Siegmund, K. and Lipp, M. and Hamann, A. and Huehn, J.
European Journal of Immunology 37 (6): 1575-1583. June 2007

CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity.
Hoepken, U.E. and Wengner, A.M. and Loddenkemper, C. and Stein, H. and Heimesaat, M.M. and Rehm, A. and Lipp, M.
Blood 109 (3): 886-895. 1 February 2007

Mycobacterium tuberculosis triggers formation of lymphoid structure in murine lungs.
Kahnert, A. and Hoepken, U.E. and Stein, M. and Bandermann, S. and Lipp, M. and Kaufmann, S.H.
Journal of Infectious Diseases 195 (1): 46-54. 1 January 2007

2006

Salmonella typhimurium infection triggers dendritic cells and macrophages to adopt distinct migration patterns in vivo.
Zhao, C. and Wood, M.W. and Galyov, E.E. and Hoepken, U.E. and Lipp, M. and Bodmer, H.C. and Tough, D.F. and Carter, R.W.
European Journal of Immunology 36 (11): 2939-2950. November 2006

2005

The ratio between dendritic cells and T cells determines the outcome of their encounter: Proliferation versus deletion.
Hoepken, U.E. and Lehmann, I. and Droese, J. and Lipp, M. and Schueler, T. and Rehm, A.
European Journal of Immunology 35 (10): 2851-2863. 23 September 2005

Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection.
Kursar, M. and Hoepken, U.E. and Koch, M. and Koehler, A. and Lipp, M. and Kaufmann, S.H. and Mittruecker, H.W.
Journal of Experimental Medicine 201 (9): 1447-1457. 2 May 2005

2004

HCMV-encoded chemokine receptor US28 employs multiple routes for internalization.
Droese, J. and Mokros, T. and Hermosilla, R. and Schuelein, R. and Lipp, M. and Hoepken, U.E. and Rehm, A.
Biochemical and Biophysical Research Communications 322 (1): 42-49. 10 September 2004

Distinct and overlapping roles of CXCR5 and CCR7 in B-1 cell homing and early immunity against bacterial pathogens.
Hoepken, U.E. and Achtman, A.H. and Krueger, K. and Lipp, M.
Journal of Leukocyte Biology 76 (3): 709-718. September 2004

All roads lead to rome: triggering dendritic cell migration.
Hoepken, U.E. and Lipp, M.
Immunity 20 (3): 244-246. March 2004

The chemokine receptor CCR7 controls lymph node-dependent cytotoxic T cell priming in alloimmune responses.
Hoepken, U.E. and Droese, J. and Li, J.P. and Joergensen, J. and Breitfeld, D. and Zerwes, H.G. and Lipp, M.
European Journal of Immunology 34 (2): 461-470. 1 January 2004

2003

The impact of CCR7 and CXCR5 on lymphoid organ development and systemic immunity.
Mueller, G. and Hoepken, U.E. and Lipp, M.
Immunological Reviews 195 (1): 117-135. October 2003

Regulation of dendritic cell migration to the draining lymph node: Impact on T lymphocyte traffic and priming.
Martin-Fontecha, A. and Sebastiani, S. and Hoepken, U.E. and Uguccioni, M. and Lipp, M. and Lanzavecchia, A. and Sallusto, F.
Journal of Experimental Medicine 198 (4): 615-621. 18 August 2003

Role of homeostatic chemokine and sphingosine-1-phosphate receptors in the organization of lymphoid tissue.
Mueller, G. and Reiterer, P. and Hoepken, U.E. and Golfier, S. and Lipp, M.
Annals of the New York Academy of Sciences 987 : 107-116. April 2003

2002

Systemic immunoregulatory and pathogenic functions of homeostatic chemokine receptors.
Mueller, G. and Hoepken, U.E. and Stein, H. and Lipp, M.
Journal of Leukocyte Biology 72 (1): 1-8. July 2002

In vivo differentiated cytokine-producing CD4+ T cells express functional CCR7.
Debes, G.F. and Hoepken, U.E. and Hamann, A.
Journal of Immunology 168 (11): 5441-5447. 1 June 2002

Human cytomegalovirus gene products US2 and US11 differ in their ability to attack major histocompatibility class I heavy chains in dendritic cells.
Rehm, A. and Engelsberg, A. and Tortorella, D. and Koerner, I.J. and Lehmann, I. and Ploegh, H.L. and Hoepken, U.E.
Journal of Virology 76 (10): 5043-5050. May 2002

Role for CCR7 Ligands in the emigration of newly generated T lymphocytes from the neonatal thymus.
Ueno, T. and Hara, K. and Willis, M.S. and Malin, M.A. and Hoepken, U.E. and Gray, D.H.D. and Matsushima, K. and Lipp, M. and Springer, T.A. and Boyd, R.L. and Yoshie, O. and Takahama, Y.
Immunity 16 (2): 205-218. 1 January 2002

Surface expression and endocytosis of the human cytomegalovirus-encoded chemokine receptor US28 is regulated by agonist-independent phosphorylation.
Mokros, T. and Rehm, A. and Droese, J. and Oppermann, M. and Lipp, M. and Hoepken, U.E.
Journal of Biological Chemistry 277 (47): 45122-45128. 1 January 2002

Up-regulation of the chemokine receptor CCR7 in classical but not in lymphocyte-predominant Hodgkin disease correlates with distinct dissemination of neoplastic cells in lymphoid organs.
Hoepken, U.E. and Foss, H.D. and Meyer, D. and Hinz, M. and Leder, K. and Stein, H. and Lipp, M.
Blood 99 (4): 1109-1116. 1 January 2002

1999

Expression of C5a receptor in mouse brain: role in signal transduction and neurodegeneration.
Osaka, H. and McGinty, A. and Hoepken, U.E. and Lu, B. and Gerard, C. and Pasinetti, G.M.
Neuroscience 88 (4): 1073-1082. February 1999

1998

Effects of anti-C5a monoclonal antibodies on oxygen use in a porcine model of severe sepsis.
Mohr, M. and Hoepken, U. and Oppermann, M. and Mathes, C. and Goldmann, K. and Siever, S. and Goetze, O. and Burchardi, H.
European Journal of Clinical Investigation 28 (3): 227-234. March 1998

1997

Impaired inflammatory responses in the reverse arthus reaction through genetic deletion of the C5a receptor.
Hoepken, U.E. and Lu, B. and Gerard, N.P. and Gerard, C.
Journal of Experimental Medicine 186 (5): 749-756. 29 August 1997

Alternate splicing of mouse fusin/CXC chemokine receptor-4: stromal cell-derived factor-1α is a ligand for both CXC chemokine receptor-4 isoforms.
Heesen, M. and Berman, M.A. and Hoepken, U.E. and Gerard, N.P. and Dorf, M.E.
Journal of Immunology 158 (8): 3561-3564. 15 April 1997

1996

Neurogenic amplification of immune complex inflammation.
Bozic, C.R. and Lu, B. and Hoepken, U.E. and Gerard, C. and Gerard, N.P.
Science 273 (5282): 1722-1725. 20 September 1996

The C5a chemoattractant receptor mediates mucosal defence to infection.
Hoepken, U.E. and Lu, B. and Gerard, N.P. and Gerard, C.
Nature 383 (6595): 86-89. 5 September 1996

Inhibition of interleukin-6 synthesis in an animal model of septic shock by anti-C5a monoclonal antibodies.
Hoepken, U. and Mohr, M. and Strueber, A. and Montz, H. and Burchardi, H. and Goetze, O. and Oppermann, M.
European Journal of Immunology 26 (5): 1103-1109. May 1996

This list was generated on Wed Nov 14 02:21:13 2018 CET.
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