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2024

USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
Reissland, M., Hartmann, O., Tauch, S., Bugter, J.M., Prieto-Garcia, C., Schulte, C., Loebbert, S., Solvie, D., Bitman-Lotan, E., Narain, A., Jacomin, A.C., Schuelein-Voelk, C., Fuss, C.T., Pahor, N., Ade, C., Buck, V., Potente, M., Li, V., Beliu, G., Wiegering, A., Grossmann, T., Eilers, M., Wolf, E., Maric, H., Rosenfeldt, M., Maurice, M.M., Dikic, I., Gallant, P., Orian, A. and Diefenbacher, M.E.
Oncogene 43 (50): 3645-3659. 2 December 2024

LncRNA MIR31HG fosters stemness malignant features of non-small cell lung cancer via H3K4me1- and H3K27Ace-mediated GLI2 expression.
Chen, W., Wang, F., Yu, X., Qi, J., Dong, H., Cui, B., Zhang, Q., Wu, Y., An, J., Ni, N., Liu, C., Han, Y., Zhang, S., Schmitt, C.A., Deng, J., Yu, Y. and Du, J.
Oncogene 43 (18): 1328-1340. 2 May 2024

2022

Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis.
Kortüm, B., Radhakrishnan, H., Zincke, F., Sachse, C., Burock, S., Keilholz, U., Dahlmann, M., Walther, W., Dittmar, G., Kobelt, D. and Stein, U.
Oncogene 41 (39): 4446-4458. 23 September 2022

2021

Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma.
Bischoff, P., Trinks, A., Obermayer, B., Pett, J.P., Wiederspahn, J., Uhlitz, F., Liang, X., Lehmann, A., Jurmeister, P., Elsner, A., Dziodzio, T., Rückert, J.C., Neudecker, J., Falk, C., Beule, D., Sers, C., Morkel, M., Horst, D., Blüthgen, N. and Klauschen, F.
Oncogene 40 : 6748–6758. 16 December 2021

The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Kobelt, D., Perez-Hernandez, D., Fleuter, C., Dahlmann, M., Zincke, F., Smith, J., Migotti, R., Popp, O., Burock, S., Walther, W., Dittmar, G., Mertins, P. and Stein, U.
Oncogene 40 (34): 5286-5301. 26 August 2021

2019

Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.
Rohwer, N., Jumpertz, S., Erdem, M., Egners, A., Warzecha, K.T., Fragoulis, At., Kühl, A.A., Kramann, R., Neuss, S., Rudolph, I., Endermann, T., Zasada, C., Apostolova, I., Gerling, M., Kempa, S., Hughes, R., Lewis, C.E., Brenner, W., Malinowski, M.B., Stockmann, M., Schomburg, L., Faller, W., Sansom, O.J., Tacke, F., Morkel, M. and Cramer, T.
Oncogene 38 (28): 5670-5685. 11 July 2019

2017

Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma.
Arslan, A.D., Sassano, A., Saleiro, D., Lisowski, P., Kosciuczuk, E.M., Fischietti, M., Eckerdt, F., Fish, E.N. and Platanias, L.C.
Oncogene 36 (43): 6006-6019. 26 October 2017

TMEM43/LUMA is a key signaling component mediating EGFR-induced NF-κB activation and tumor progression.
Jiang, C., Zhu, Y., Zhou, Z., Gumin, J., Bengtsson, L., Wu, W., Songyang, Z., Lang, F.F. and Lin, X.
Oncogene 36 (20): 2813-2823. 18 May 2017

2016

SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival.
Schmid, F., Wang, Q., Huska, M.R., Andrade-Navarro, M.A., Lemm, M., Fichtner, I., Dahlmann, M., Kobelt, D., Walther, W., Smith, J., Schlag, P.M. and Stein, U.
Oncogene 35 (46): 5942-5952. 17 November 2016

Comprehensive translational control of tyrosine kinase expression by upstream open reading frames.
Wethmar, K., Schulz, J., Muro, E.M., Talyan, S., Andrade-Navarro, M.A. and Leutz, A.
Oncogene 35 (13): 1736-1742. 31 March 2016

2015

A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4.
Hansen, M.T., Forst, B., Cremers, N., Quagliata, L., Ambartsumian, N., Grum-Schwensen, B., Klingelhoefer, J., Abdul-Al, A., Herrmann, P., Osterland, M., Stein, U., Nielsen, G.H., Scherer, P.E., Lukanidin, E., Sleeman, J.P. and Grigorian, M.
Oncogene 34 (4): 424-435. 22 January 2015

2013

The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond.
Rohwer, N., Zasada, C., Kempa, S. and Cramer, T.
Oncogene 32 (31): 3569-3576. 1 August 2013

2012

The immediate early gene Ier2 promotes tumor cell motility and metastasis, and predicts poor survival of colorectal cancer patients.
Neeb, A., Wallbaum, S., Novac, N., Dukovic-Schulze, S., Scholl, I., Schreiber, C., Schlag, P., Moll, J., Stein, U. and Sleeman, J.P.
Oncogene 31 (33): 3796-3806. August 2012

2011

Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Fagerli, U.M., Ullrich, K., Stuehmer, T., Holien, T., Koechert, K., Holt, R.U., Bruland, O., Chatterjee, M., Nogai, H., Lenz, G., Shaughnessy, J.D., Mathas, S., Sundan, A., Bargou, R.C., Doerken, B., Borset, M. and Janz, M.
Oncogene 30 (28): 3198-3206. 14 July 2011

High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas.
Koechert, K., Ullrich, K., Kreher, S., Aster, J.C., Kitagawa, M., Joehrens, K., Anagnostopoulos, I., Jundt, F., Lamprecht, B., Zimber-Strobl, U., Stein, H., Janz, M., Doerken, B. and Mathas, S.
Oncogene 30 (15): 1831-1840. 14 April 2011

2010

The immune response to sporadic colorectal cancer in a novel mouse model.
Czeh, M., Loddenkemper, C., Shalapour, S., Schoen, C., Robine, S., Goldscheid, E., Stein, H., Schueler, T., Willimsky, G. and Blankenstein, T.
Oncogene 29 (50): 6591-6602. 16 December 2010

ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
Mueller, T., Stein, U., Poletti, A., Garzia, L., Rothley, M., Plaumann, D., Thiele, W., Bauer, M., Galasso, A., Schlag, P., Pankratz, M., Zollo, M. and Sleeman, J.P.
Oncogene 29 (16): 2393-2403. 22 April 2010

2008

Cooperative effect of p21Cip1/WAF-1 and 14-3-3sigma on cell cycle arrest and apoptosis induction by p14ARF.
Hemmati, P.G., Normand, G., Gillissen, B., Wendt, J., Doerken, B. and Daniel, P.T.
Oncogene 27 (53): 6707-6719. 4 December 2008

Positive and negative influences of regulatory T cells on tumour immunity.
Gallimore, A.M. and Simon, A.K.
Oncogene 27 (45): 5886-93. 6 October 2008

Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72.
Reinbold, M., Luo, J.L., Nedelko, T., Jerchow, B., Murphy, M.E., Whibley, C., Wei, Q. and Hollstein, M.
Oncogene 27 (19): 2788-2794. 24 April 2008

2007

Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance.
Zantl, N., Weirich, G., Zall, H., Seiffert, B.M., Fischer, S.F., Kirschnek, S., Hartmann, C., Fritsch, R.M., Gillissen, B., Daniel, P.T. and Haecker, G.
Oncogene 26 (49): 7038-7048. 25 October 2007

Enhanced tumorigenicity of fibroblasts transformed with human herpesvirus 8 chemokine receptor vGPCR by successive passage in nude and immunocompetent mice.
Thirunarayanan, N., Cifire, F., Fichtner, I., Posner, S., Benga, J., Reiterer, P., Kremmer, E., Koelble, K. and Lipp, M.
Oncogene 26 (39): 5702-5712. 23 August 2007

2006

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription.
Scheidereit, C.
Oncogene 25 (51): 6685-6705. 30 October 2006

Bak functionally complements for loss of Bax during p14(ARF)-induced mitochondrial apoptosis in human cancer cells.
Hemmati, P.G., Guener, D., Gillissen, B., Wendt, J., von Haefen, C., Chinnadurai, G., Doerken, B. and Daniel, P.T.
Oncogene 25 (50): 6582-6594. 26 October 2006

Combined treatment of colorectal tumours with agonistic TRAIL receptor antibodies HGS-ETR1 and HGS-ETR2 and radiotherapy: enhanced effects in vitro and dose-dependent growth delay in vivo.
Marini, P., Denzinger, S., Schiller, D., Kauder, S., Welz, S., Humphreys, R., Daniel, P.T., Jendrossek, V., Budach, W. and Belka, C.
Oncogene 25 : 5145-5154. 24 August 2006

Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.
Burek, M., Maddika, S., Burek, C.J., Daniel, P.T., Schulze-Osthoff, K. and Los, M.
Oncogene 25 : 2213-2222. 6 April 2006

A novel Bcl-x splice product, Bcl-xAK, triggers apoptosis in human melanoma cells without BH3 domain.
Hossini, A.M., Geilen, C.C., Fecker, L.F., Daniel, P.T. and Eberle, J.
Oncogene 25 : 2160-2169. 6 April 2006

ELA2 is regulated by hematopoietic transcription factors, but not repressed by AML1-ETO.
Lausen, J., Liu, S., Fliegauf, M., Luebbert, M. and Werner, M.H.
Oncogene 25 (9): 1349-1357. 2 March 2006

Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells.
Wendt, J., Radetzki, S., von Haefen, C., Hemmati, P.G., Guener, D., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 25 : 972-980. 16 February 2006

Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth.
Bhonde, M.R., Hanski, M.L., Notter, M., Gillissen, B.F., Daniel, P.T., Zeitz, M. and Hanski, C.
Oncogene 25 : 165-175. 12 January 2006

2005

Arsenic trioxide induces regulated, death receptor-independent cell death through a Bcl-2-controlled pathway.
Scholz, C., Richter, A., Lehmann, M., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 24 (47): 7031-7042. 27 October 2005

HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma.
Lucas, B., Grigo, K., Erdmann, S., Lausen, J., Klein-Hitpass, L. and Ryffel, G.U.
Oncogene 24 (42): 6418-6431. 22 September 2005

Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival.
Gyoerffy, B., Serra, V., Juerchott, K., Abdul-Ghani, R., Garber, M., Stein, U., Petersen, I., Lage, H., Dietel, M. and Schaefer, R.
Oncogene 24 (15): 7542-7551. 25 July 2005

Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk/Bik.
Oppermann, M., Geilen, C.C., Fecker, L.F., Gillissen, B., Daniel, P.T. and Eberle, J.
Oncogene 24 : 7369-7380. 4 July 2005

The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-xL protein.
Bhonde, M.R., Hanski, M.L., Magrini, R., Moorthy, D., Mueller, A., Sausville, E.A., Kohno, K., Wiegand, P., Daniel, P.T., Zeitz, M. and Hanski, C.
Oncogene 24 : 148-156. 6 January 2005

Type I and type II reactions in TRAIL-induced apoptosis - results from dose-response studies.
Rudner, J., Jendrossek, V., Lauber, K., Daniel, P.T., Wesselborg, S. and Belka, C.
Oncogene 24 : 130-140. 6 January 2005

Recurrent chromosomal aberrations in INK4a/ARF defective primary lymphomas predict drug responses in vivo.
Helmrich, A., Lee, S., O'Brien, P., Doerken, B., Lowe, S.W., Schroeck, E. and Schmitt, C.A.
Oncogene 24 : 4174-4182. 1 January 2005

Loss of p21 disrupts p14ARF-induced G1 cell cycle arrest but augments p14ARF-induced apoptosis in human carcinoma cells.
Hemmati, P.G., Normand, G., Verdoodt, B., von Haefen, C., Hasenjaeger, A., Guener, D., Wendt, J., Doerken, B. and Daniel, P.T.
Oncogene 24 (25): 4114-4128. 1 January 2005

Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway.
Scholz, C., Wieder, T., Staerck, L., Essmann, F., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 24 : 1904-1913. 1 January 2005

A network of clinically and functionally relevant genes is involved in the reversion of the tumorigenic phenotype of MDA-MB-231 breast cancer cells after transfer of human chromosome 8.
Seitz, S., Frege, R., Jacobsen, A., Weimer, J., Arnold, W., Haefen, C.v., Niederacher, D., Schmutzler, R., Arnold, N. and Scherneck, S.
Oncogene 24 (5): 869-879. 1 January 2005

YB-1 facilitates basal and 5-fluorouracil-inducible expression of the human major vault protein (MVP) gene.
Stein, U., Bergmann, S., Scheffer, G.L., Scheper, R.J., Royer, H.D., Schlag, P.M. and Walther, W.
Oncogene 24 (22): 3606-3618. 1 January 2005

TRAIL sensitizes for ionizing irradiation-induced apoptosis through an entirely Bax-dependent mitochondrial cell death pathway.
Wendt, J., von Haefen, C., Hemmati, P., Belka, C., Doerken, B. and Daniel, P.T.
Oncogene 24 (25): 4052-4064. 1 January 2005

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation.
Yu, M., Schreek, S., Cerni, C., Schamberger, C., Lesniewicz, K., Poreba, E., Vervoorts, J., Walsemann, G., Groetzinger, J., Kremmer, E., Mehraein, Y., Mertsching, J., Kraft, R., Austen, M., Luscher-Firzlaff, J. and Luescher, B.
Oncogene 24 (12): 1982-1993. 1 January 2005

2004

ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2.
Jandrig, B., Seitz, S., Hinzmann, B., Arnold, W., Micheel, B., Koelble, K., Siebert, R., Schwartz, A., Ruecker, K., Schlag, P.M., Scherneck, S. and Rosenthal, A.
Oncogene 23 (57): 9295-9302. 18 October 2004

Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway.
von Haefen, C., Gillissen, B., Hemmati, P.G., Wendt, J., Guener, D., Mrozek, A., Belka, C., Doerken, B. and Daniel, P.T.
Oncogene 23 (50): 8320-8332. 27 September 2004

Tumor necrosis factor α sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-κB.
Schmelz, K., Wieder, T., Tamm, I., Mueller, A., Essmann, F., Geilen, C.C., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 23 (40): 6743-6759. 2 September 2004

Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.
Broemer, M., Krappmann, D. and Scheidereit, C.
Oncogene 23 (31): 5378-5386. 8 July 2004

Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-xL in a strictly caspase-3-dependent manner in human carcinoma cells.
Hasenjaeger, A., Gillissen, B., Mueller, A., Normand, G., Hemmati, P.G., Schuler, M., Doerken, B. and Daniel, P.T.
Oncogene 23 (26): 4523-4535. 3 June 2004

Adenine deoxynucleotides fludarabine and cladribine induce apoptosis in a CD95/Fas receptor, FADD and caspase-8-independent manner by activation of the mitochondrial cell death pathway.
Kloepfer, A., Hasenjaeger, A., Belka, C., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 23 : 9408-9418. 1 January 2004

2003

CD95/Fas signaling in human melanoma cells: conditional expression of CD95L/FasL overcomes the intrinsic apoptosis resistance of malignant melanoma and inhibits growth and progression of human melanoma xenotransplants.
Eberle, J., Fecker, L.F., Hossini, A.M., Wieder, T., Daniel, P.T., Orfanos, C.E. and Geilen, C.C.
Oncogene 22 (57): 9131-9141. 11 December 2003

Induction of apoptosis by enediyne antibiotic calicheamicin gammaII proceeds through a caspase-mediated mitochondrial amplification loop in an entirely Bax-dependent manner.
Prokop, A., Wrasidlo, W., Lode, H., Herold, R., Lang, F., Henze, G., Doerken, B., Wieder, T. and Daniel, P.T.
Oncogene 22 (57): 9107-9120. 11 December 2003

Induction of G0/G1 cell cycle arrest in ovarian carcinoma cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference.
Denkert, C., Fuerstenberg, A., Daniel, P.T., Koch, I., Koebel, M., Weichert, W., Siegert, A. and Hauptmann, S.
Oncogene 22 (54): 8653-8661. 27 November 2003

SASH1: a candidate tumor suppressor gene on chromosome 6q24.3 is downregulated in breast cancer.
Zeller, C., Hinzmann, B., Seitz, S., Prokoph, H., Burkhard-Goettges, E., Fischer, J., Jandrig, B., Schwarz, L.E., Rosenthal, A. and Scherneck, S.
Oncogene 22 (19): 2972-2983. 15 May 2003

Pathogenesis of DNA repair-deficient cancers: a statistical meta-analysis of putative Real Common Target genes.
Woerner, S.M., Benner, A., Sutter, C., Schiller, M., Yuan, Y.P., Keller, G., Bork, P., Doeberitz, M.V. and Gebert, J.F.
Oncogene 22 (15): 2226-2235. 17 April 2003

GATA-1 and c-myb crosstalk during red blood cell differentiation through GATA-1 binding sites in the c-myb promoter.
Bartunek, P., Kralova, J., Blendinger, G., Dvorak, M. and Zenke, M.
Oncogene 22 (13): 1927-1935. 3 April 2003

Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop.
von Haefen, C., Wieder, T., Essmann, F., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 22 (15): 2236-2247. 1 April 2003

Overexpression of NPM-ALK induces different types of malignant lymphomas in IL-9 transgenic mice.
Lange, K., Uckert, W., Blankenstein, T., Nadrowitz, R., Bittner, C., Renauld, J.C., van Snick, J., Feller, A.C. and Merz, H.
Oncogene 22 (4): 517-527. 30 January 2003

Distinct changes in gene expression induced by A-Myb, B-Myb and c-Myb proteins.
Rushton, J.J., Davis, L.M., Lei, W.L., Mo, X.M., Leutz, A. and Ness, S.A.
Oncogene 22 (2): 308-313. 16 January 2003

2002

Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells.
von Haefen, C., Wieder, T., Gillissen, B., Staerck, L., Graupner, V., Doerken, B. and Daniel, P.T.
Oncogene 21 (25): 4009-4019. 6 June 2002

Adenovirus-mediated overexpression of p14ARF induces p53 and Bax-independent apoptosis.
Hemmati, P.G., Gillissen, B., von Haefen, C., Wendt, J., Staerck, L., Guener, D., Doerken, B. and Daniel, P.T.
Oncogene 21 (20): 3149-3161. 9 May 2002

bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors.
Bartunek, P., Pajer, P., Karafiat, V., Blendinger, G., Dvorak, M. and Zenke, M.
Oncogene 21 (3): 400-410. 17 January 2002

The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines.
Radetzki, S., Koehne, C.H., von Haefen, C., Gillissen, B., Sturm, I., Doerken, B. and Daniel, P.T.
Oncogene 21 (2): 227-238. 10 January 2002

Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells.
Grinstein, E., Jundt, F., Weinert, I., Wernet, P. and Royer, H.D.
Oncogene 21 : 1485-1492. 1 January 2002

The breast proto-oncogene, HRGalpha regulates epithelial proliferation and lobuloalveolar development in the mouse mammary gland.
Li, L., Cleary, S., Mandarano, M.A., Long, W.W., Birchmeier, C. and Jones, F.E.
Oncogene 21 : 4900-4907. 1 January 2002

2001

A rapid bioinformatic method identifies novel genes with direct clinical relevance to colon cancer.
Brett, D., Kemmner, W., Koch, G., Roefzaad, C., Gross, S. and Schlag, P.M.
Oncogene 20 (33): 4581-4585. 27 July 2001

Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance.
Friedrich, K., Wieder, T., von Haefen, C., Radetzki, S., Jaenicke, R., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 20 (22): 2749-2760. 17 May 2001

The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif.
Lewitzky, M., Kardinal, C., Gehring, N.H., Schmidt, E.K., Konkol, B., Eulitz, M., Birchmeier, W., Schaeper, U. and Feller, S.M.
Oncogene 20 (9): 1052-1062. 1 January 2001

Tumorigenic N-terminal deletions of c-Myb modulate DNA binding, transactivation, and cooperativity with C/EBP.
Oelgeschlager, M., Kowenz-Leutz, E., Schreek, S., Leutz, A. and Luescher, B.
Oncogene 20 (50): 7420-7424. 1 January 2001

2000

Mammary gland specific hEGF receptor transgene expression induces neoplasia and inhibits differentiation.
Brandt, R., Eisenbrandt, R., Leenders, F., Zschiesche, W., Binas, B., Juergensen, C. and Theuring, F.
Oncogene 19 : 2129-2137. 20 April 2000

1999

Cytokine response gene 6 induces p21 and regulates both cell growth and arrest.
Fan, W., Richter, G., Cereseto, A., Beadling, C. and Smith, K.A.
Oncogene 18 : 6573-6582. 11 November 1999

The fibroblast growth factor receptor FGFR-4 acts as a ligand dependent modulator of erythroid cell proliferation.
Koritschoner, N.P., Bartunek, P., Knespel, S., Blendinger, G. and Zenke, M.
Oncogene 18 (43): 5904-5914. 21 October 1999

Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility.
Handschuh, G., Candidus, S., Luber, B., Reich, U., Schott, C., Oswald, S., Becke, H., Hutzler, P., Birchmeier, W., Hoefler, H. and Becker, K.F.
Oncogene 18 : 4301-4312. 29 July 1999

The Bcl-3 oncoprotein acts as a bridging factor between NF-kappa B/Rel and nuclear co-regulators.
Dechend, R., Hirano, F., Lehmann, K., Heissmeyer, V., Ansieau, S., Wulczyn, F.G., Scheidereit, C. and Leutz, A.
Oncogene 18 : 3316-3323. 3 June 1999

Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.
Krappmann, D., Emmerich, F., Kordes, U., Scharschmidt, E., Doerken, B. and Scheidereit, C.
Oncogene 18 : 943-953. 28 January 1999

1998

Secretory Type II Phospholipase A2 (PLA2G2A) expression status in colorectal carcinoma derived cell lines and in normal colonic mucosa.
Praml, C., Amler, L.C., Dihlmann, S., Finke, L.H., Schlag, P.M. and Schwab, M.
Oncogene 17 : 2009-2012. 15 October 1998

Cyclin D3: requirement for G1/S transition and high abundance in quiescent tissues suggest a dual role in proliferation and differentiation.
Bartkova, J., Lukas, J., Strauss, M. and Bartek, J.
Oncogene 17 (8): 1027-1037. 27 August 1998

Role of morphogenetic factors in metastasis of mammary carcinoma cells.
Meiners, S., Brinkmann, V., Naundorf, H. and Birchmeier, W.
Oncogene 16 : 9-20. 1 January 1998

1997

The Myb leucine zipper is essential for leukemogenicity of the v-Myb protein.
Bartunek, P., Karafiat, V., Dvorakova, M., Zahorova, V., Mandikova, S., Zenke, M. and Dvorak, M.
Oncogene 15 (24): 2939-2949. 11 December 1997

Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2.
Besser, D., Bardelli, A., Didichenko, S., Thelen, M., Comoglio, P.M., Ponzetto, C. and Nagamine, Y.
Oncogene 14 (6): 705-711. 13 February 1997

Strong indication for a breast cancer susceptibility gene on chromosome 8p12-p22: linkage analysis in german breast cancer families.
Seitz, S., Rohde, K., Bender, E., Nothnagel, A., Koelble, K., Schlag, P.M. and Scherneck, S.
Oncogene 14 (6): 741-743. 13 February 1997

Functional interference between retinoic acid or steroid hormone receptors and the oncoprotein Fli-1.
Darby, T.G., Meissner, J., Ruehlmann, A., Mueller, W.H. and Scheibe, R.J.
Oncogene 15 : 3067-3082. 1 January 1997

1996

A defined chromosome 6q fragment (at D6S310) harbors a putative tumor suppressor gene for breast cancer.
Theile, M., Seitz, S., Arnold, W., Jandrig, B., Frege, R., Schlag, P.M., Haensch, W., Guski, H., Winzer, K.J., Barrett, J.C. and Scherneck, S.
Oncogene 13 (4): 677-685. 15 August 1996

The retinoblastoma protein modulates expression of genes coding for diverse classes of proteins including components of the extracellular matrix.
Rohde, M., Warthoe, P., Gjetting, T., Lukas, J., Bartek, J. and Strauss, M.
Oncogene 12 (11): 2393-2401. 6 June 1996

1995

The BTB/POZ domain targets the LAZ3/BCL6 oncoprotein to nuclear dots and mediates homomerisation in vivo.
Dhordain, P., Albagli, O., Ansieau, S., Koken, M., Deweindt, C., Quief, S., Lantoine, D., Leutz, A., Kerckaert, J.P. and Leprince, D.
Oncogene 11 (12): 2689-2697. 21 December 1995

Urokinase-type plasminogen activator gene regulation by polyomavirus middle-T antigen.
Besser, D., Urich, M., Sakaue, M., Messerschmitt, A., Ballmer-Hofer, K. and Nagamine, Y.
Oncogene 11 (11): 2383-2391. 7 December 1995

Deletion mapping defines different regions in 1p34.2-pter that may harbor genetic information related to human colorectal cancer.
Praml, C., Finke, L.H., Herfarth, C., Schlag, P.M., Schwab, M. and Amler, L.
Oncogene 11 (7): 1357-1362. 5 October 1995

Suppression of tumorigenicity of breast cancer cells by transfer of human chromosome 17 does not require transferred BRCA1 and p53 genes.
Theile, M., Hartmann, S., Scherthan, H., Arnold, W., Deppert, W., Frege, R., Glaab, F., Haensch, W. and Scherneck, S.
Oncogene 10 (3): 439-447. 2 February 1995

Immediate effects of reversible HTLV-I tax function: T-cell activation and apoptosis.
Chlichlia, K., Moldenhauer, G., Daniel, P.T., Busslinger, M., Gazzalo, L., Schirrmacher, V. and Khazaie, K.
Oncogene 10 (2): 269-277. 19 January 1995

Progression of carcinoma cells is associated with alterations in chromatin structure and factor binding at the E-cadherin promoter in vivo.
Hennig, G., Behrens, J., Truss, M., Frisch, S., Reichmann, E. and Birchmeier, W.
Oncogene 11 : 475-484. 1 January 1995

1994

Biochemical and functional characterization of the murine ros protooncogene.
Riethmacher, D., Langholz, O., Goedecke, S., Sachs, M. and Birchmeier, C.
Oncogene 9 (12): 3617-3626. December 1994

Transcriptional repression and activation in the same cell type of the human c-MYC promoter by the retinoblastoma gene protein: antagonisation of both effects by SV40 T antigen.
Batsche, E., Lipp, M. and Cremisi, C.
Oncogene 9 (8): 2235-2243. August 1994

BCL-1/cyclin D1 oncoprotein oscillates and subverts the G1 phase control in B-cell neoplasms carrying the t(11;14) translocation.
Lukas, J., Jadayel, D., Bartkova, J., Nacheva, E., Dyer, M.J.S., Strauss, M. and Bartek, J.
Oncogene 9 (8): 2159-2167. August 1994

E2F-dependent regulation of human MYC: trans-activation by cyclins D1 and A overrides tumour suppressor protein functions.
Oswald, F., Lovec, H., Moeroey, T. and Lipp, M.
Oncogene 9 (7): 2029-2036. July 1994

Functional aspects of B-Myb in early Xenopus development.
Bouwmeester, T., van Wijk, I., Wedlich, D. and Pieler, T.
Oncogene 9 (4): 1029-1038. April 1994

1993

NF-kappaB precursor p100 inhibits nuclear translocation and DNA binding of NF-kappaB/rel-factors.
Naumann, M., Nieters, A., Hatada, E.N. and Scheidereit, C.
Oncogene 8 (8): 2275-2281. 1 August 1993

Mutations within the hamster polyomavirus large T antigen domain involved in pRb binding impair virus productive cycle and immortalization capacity.
Goutebroze, L., De La Roche Saint Andre, C., Scherneck, S. and Feunteun, J.
Oncogene 8 : 685-693. 1 January 1993

Characterization of the transcriptional regulatory region of the human WT1 gene.
Hofmann, W., Royer, H.D., Drechsler, M., Schneider, S. and Royer-Pokora, B.
Oncogene 8 : 3123-3132. 1 January 1993

Transcriptional activation and transformation by chimaeric Fos-estrogen receptor proteins: altered properties as a consequence of gene fusion.
Schuermann, M., Hennig, G. and Mueller, R.
Oncogene 8 : 2781-2790. 1 January 1993

1992

Modulation of normal erythroid differentiation by the endogenous thyroid hormone and retinoic acid receptors: a possible target for v-erbA oncogene action.
Schroeder, C., Gibson, L., Zenke, M. and Beug, H.
Oncogene 7 (2): 217-227. 1 February 1992

Stimulation of cell division and fibroblast focus formation by antisense repression of retinoblastoma protein synthesis.
Strauss, M., Hering, S., Lieber, A., Herrmann, G., Griffin, B.E. and Arnold, W.
Oncogene 7 : 769-773. 1 January 1992

1991

Cell transformation by Int-2 - a member of the fibroblast growth factor family.
Goldfarb, M., Deed, R., MacAllan, D., Walther, W., Dickson, C. and Peters, G.
Oncogene 6 : 65-71. 1 January 1991

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