Browse by Journal Title

2020

The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization.
Daniel, B. and Czimmerer, Z. and Halasz, L. and Boto, P. and Kolostyak, Z. and Poliska, S. and Berger, W.K. and Tzerpos, P. and Nagy, G. and Horvath, A. and Hajas, G. and Cseh, T. and Nagy, A. and Sauer, S. and Francois-Deleuze, J. and Szatmari, I. and Bacsi, A. and Nagy, L.
Genes & Development 34 (21-22): 1474-1492. 1 November 2020

2019

Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat.
Labi, V. and Peng, S. and Klironomos, F. and Munschauer, M. and Kastelic, N. and Chakraborty, T. and Schoeler, K. and Derudder, E. and Martella, M. and Mastrobuoni, G. and Hernandez-Miranda, L.R. and Lahmann, I. and Kocks, C. and Birchmeier, C. and Kempa, S. and Quintanilla-Martinez de Fend, L. and Landthaler, M. and Rajewsky, N. and Rajewsky, K.
Genes & Development 33 : 23-24. 7 November 2019

Human stem cell models: lessons for pancreatic development and disease.
Gaertner, B. and Carrano, A.C. and Sander, M.
Genes & Development 33 (21-22): 1475-1490. 1 November 2019

Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells.
Lahmann, I. and Bröhl, D. and Zyrianova, T. and Isomura, A. and Czajkowski, M.T. and Kapoor, V. and Griger, J. and Ruffault, P.L. and Mademtzoglou, D. and Zammit, P.S. and Wunderlich, T. and Spuler, S. and Kühn, R. and Preibisch, S. and Wolf, J. and Kageyama, R. and Birchmeier, C.
Genes & Development 33 (9-10): 524-535. 1 May 2019

2018

Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.
Cantù, C. and Felker, A. and Zimmerli, D. and Prummel, K.D. and Cabello, E.M. and Chiavacci, E. and Méndez-Acevedo, K.M. and Kirchgeorg, L. and Burger, S. and Ripoll, J. and Valenta, T. and Hausmann, G. and Vilain, N. and Aguet, M. and Burger, A. and Panáková, D. and Basler, K. and Mosimann, C.
Genes & Development 32 (21-22): 1443-1458. 1 November 2018

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Kim, M. and Wende, H. and Walcher, J. and Kühnemund, J. and Cheret, C. and Kempa, S. and McShane, E. and Selbach, M. and Lewin, G.R. and Birchmeier, C.
Genes & Development 32 (9-10): 645-657. 10 May 2018

Athymic mice reveal a requirement for T-cell-microglia interactions in establishing a microenvironment supportive of Nf1 low-grade glioma growth.
Pan, Y. and Xiong, M. and Chen, R. and Ma, Y. and Corman, C. and Maricos, M. and Kindler, U. and Semtner, M. and Chen, Y.H. and Dahiya, S. and Gutmann, D.H.
Genes & Development 32 (7-8): 491-496. 9 April 2018

2017

Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive C. elegans.
Wilhelm, T. and Byrne, J. and Medina, R. and Kolundžić, E. and Geisinger, J. and Hajduskova, M. and Tursun, B. and Richly, H.
Genes & Development 31 (15): 1561-1572. 1 August 2017

2014

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E. and McShane, E. and Cheret, C. and Walcher, J. and Müller, T. and Wulf-Goldenberg, A. and Hoelper, S. and Garratt, A.N. and Krüger, M. and Rajewsky, K. and Meijer, D. and Birchmeier, W. and Lewin, G.R. and Selbach, M. and Birchmeier, C.
Genes & Development 28 (3): 290-303. 1 February 2014

A conserved role for Snail as a potentiator of active transcription.
Rembold, M. and Ciglar, L. and Yáñez-Cuna, J.O. and Zinzen, R.P. and Girardot, C. and Jain, A. and Welte, M.A. and Stark, A. and Leptin, M. and Furlong, E.E.M.
Genes & Development 28 (2): 167-181. 15 January 2014

Two distinct types of neuronal asymmetries are controlled by the Caenorhabditis elegans zinc finger transcription factor die-1.
Cochella, L. and Tursun, B. and Hsieh, Y.W. and Galindo, S. and Johnston, R.J. and Chuang, C.F. and Hobert, O.
Genes & Development 28 (1): 34-43. 1 January 2014

2013

Induction of sarcomas by mutant IDH2.
Lu, C. and Venneti, S. and Akalin, A. and Fang, F. and Ward, P.S. and Dematteo, R.G. and Intlekofer, A.M. and Chen, C. and Ye, J. and Hameed, M. and Nafa, K. and Agaram, N.P. and Cross, J.R. and Khanin, R. and Mason, C.E. and Healey, J.H. and Lowe, S.W. and Schwartz, G.K. and Melnick, A. and Thompson, C.B.
Genes & Development 27 (18): 1986-1998. 15 September 2013

Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence.
Rodríguez-Seguel, E. and Mah, N. and Naumann, H. and Pongrac, I.M. and Cerdá-Esteban, N. and Fontaine, J.F. and Wang, Y. and Chen, W. and Andrade-Navarro, M.A. and Spagnoli, F.M.
Genes & Development 27 (17): 1932-1946. 1 September 2013

2012

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.
Peterson, K.A. and Nishi, Y. and Ma, W. and Vedenko, A. and Shokri, L. and Zhang, X. and McFarlane, M. and Baizabal, J.M. and Junker, J.P. and van Oudenaarden, A. and Mikkelsen, T. and Bernstein, B.E. and Bailey, T.L. and Bulyk, M.L. and Wong, W.H. and McMahon, A.P.
Genes & Development 26 (24): 2802-2816. 15 December 2012

Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number.
Sankaran, V.G. and Ludwig, L.S. and Sicinska, E. and Xu, J. and Bauer, D.E. and Eng, J.C. and Patterson, H.C. and Metcalf, R.A. and Natkunam, Y. and Orkin, S.H. and Sicinski, P. and Lander, E.S. and Lodish, H.F.
Genes & Development 26 (18): 2075-2087. 15 September 2012

Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.
Rosario, M. and Schuster, S. and Juettner, R. and Parthasarathy, S. and Tarabykin, V. and Birchmeier, W.
Genes & Development 26 (15): 1743-1757. 1 August 2012

2011

Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations.
Jing, H. and Kase, J. and Dörr, J.R. and Milanovic, M. and Lenze, D. and Grau, M. and Beuster, G. and Ji, S. and Reimann, M. and Lenz, P. and Hummel, M. and Doerken, B. and Lenz, G. and Scheidereit, C. and Schmitt, C.A. and Lee, S.
Genes & Development 25 (20): 2137-2146. 15 October 2011

Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice.
Dorrell, C. and Erker, L. and Schug, J. and Kopp, J.L. and Canaday, P.S. and Fox, A.J. and Smirnova, O. and Duncan, A.W. and Finegold, M.J. and Sander, M. and Kaestner, K.H. and Grompe, M.
Genes & Development 25 (11): 1193-203. 1 June 2011

The ERGonomics of hematopoietic stem cell self-renewal.
Lacadie, S.A. and Zon, L.I.
Genes & Development 25 (4): 289-293. 15 February 2011

2010

The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery.
Parry, T.J. and Theisen, J.W.M. and Hsu, J.Y. and Wang, Y.L. and Corcoran, D.L. and Eustice, M. and Ohler, U. and Kadonaga, J.T.
Genes & Development 24 (18): 2013-2018. 15 September 2010

C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals.
Wethmar, K. and Bégay, V. and Smink, J.J. and Zaragoza, K. and Wiesenthal, V. and Doerken, B. and Calkhoven, C.F. and Leutz, A.
Genes & Development 24 (1): 15-20. 1 January 2010

2009

A large-scale functional RNAi screen reveals a role for CK2 in the mammalian circadian clock.
Maier, B. and Wendt, S. and Vanselow, J.T. and Wallach, T. and Reischl, S. and Oehmke, S. and Schlosser, A. and Kramer, A.
Genes & Development 23 (6): 708-718. 15 March 2009

2008

Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice.
Grigoryan, T. and Wend, P. and Klaus, A. and Birchmeier, W.
Genes & Development 22 (17): 2308-2341. 1 September 2008

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.
Lange, M. and Kaynak, B. and Foerster, U.B. and Toenjes, M. and Fischer, J.J. and Grimm, C. and Schlesinger, J. and Just, S. and Dunkel, I. and Krueger, T. and Mebus, S. and Lehrach, H. and Lurz, R. and Gobom, J. and Rottbauer, W. and Abdelilah-Seyfried, S. and Sperling, S.
Genes & Development 22 (17): 2370-2384. 1 September 2008

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.
Ebralidze, A.K. and Guibal, F.C. and Steidl, U. and Zhang, P. and Lee, S. and Bartholdy, B. and Jorda, M.A. and Petkova, V. and Rosenbauer, F. and Huang, G. and Dayaram, T. and Klupp, J. and O'Brien, K.B. and Will, B. and Hoogenkamp, M. and Borden, K.L. and Bonifer, C. and Tenen, D.G.
Genes & Development 22 (15): 2085-2092. 1 August 2008

A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling.
Hori, K. and Cholewa-Waclaw, J. and Nakada, Y. and Glasgow, S.M. and Masui, T. and Henke, R.M. and Wildner, H. and Martarelli, B. and Beres, T.M. and Epstein, J.A. and Magnuson, M.A. and Macdonald, R.J. and Birchmeier, C. and Johnson, J.E.
Genes & Development 22 (2): 166-178. 15 January 2008

2007

FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf.
Bouchard, C. and Lee, S. and Paulus-Hock, V. and Loddenkemper, C. and Eilers, M. and Schmitt, C.A.
Genes & Development 21 (21): 2775-2787. 1 November 2007

Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing.
Eulalio, A. and Rehwinkel, J. and Stricker, M. and Huntzinger, E. and Yang, S.F. and Doerks, T. and Dorner, S. and Bork, P. and Boutros, M. and Izaurralde, E.
Genes & Development 21 (20): 2558-2570. 15 October 2007

SIRT1 controls endothelial angiogenic functions during vascular growth.
Potente, M. and Ghaeni, L. and Baldessari, D. and Mostoslavsky, R. and Rossig, L. and Dequiedt, F. and Haendeler, J. and Mione, M. and Dejana, E. and Alt, F.W. and Zeiher, A.M. and Dimmeler, S.
Genes & Development 21 (20): 2644-2658. 15 October 2007

Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility.
Montgomery, R.L. and Davis, C.A. and Potthoff, M.J. and Haberland, M. and Fielitz, J. and Qi, X. and Hill, J.A. and Richardson, J.A. and Olson, E.N.
Genes & Development 21 (14): 1790-1802. 15 July 2007

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.
Bracken, A.P. and Kleine-Kohlbrecher, D. and Dietrich, N. and Pasini, D. and Gargiulo, G. and Beekman, C. and Theilgaard-Moench, K. and Minucci, S. and Porse, B.T. and Marine, J.-C. and Hansen, K.H. and Helin, K.
Genes & Development 21 (5): 525-530. 1 March 2007

Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo.
Zeitlinger, J. and Zinzen, R.P. and Stark, A. and Kellis, M. and Zhang, H. and Young, R.A. and Levine, M.
Genes & Development 21 (4): 385-390. 15 February 2007

Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development.
Abramsson, A. and Kurup, S. and Busse, M. and Yamada, S. and Lindblom, P. and Schallmeiner, E. and Stenzel, D. and Sauvaget, D. and Ledin, J. and Ringvall, M. and Landegren, U. and Kjellén, L. and Bondjers, G. and Li, J.P. and Lindahl, U. and Spillmann, D. and Betsholtz, C. and Gerhardt, H.
Genes & Development 21 (3): 316-331. 1 February 2007

2006

The Zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells.
Gierl, M.S. and Karoulias, N. and Wende, H. and Strehle, M. and Birchmeier, C.
Genes & Development 20 (17): 2465-2478. 1 September 2006

In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants.
Lacadie, S.A. and Tardiff, D.F. and Kadener, S. and Rosbash, M.
Genes & Development 20 (15): 2055-2066. 1 August 2006

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes.
Behm-Ansmant, I. and Rehwinkel, J. and Doerks, T. and Stark, A. and Bork, P. and Izaurralde, E.
Genes & Development 20 : 1885-1898. 15 July 2006

2005

The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones.
Tursun, B. and Schlueter, A. and Peters, M.A. and Viehweger, B. and Ostendorff, H.P. and Soosairajah, J. and Drung, A. and Bossenz, M. and Johnsen, S.A. and Schweizer, M. and Bernard, O. and Bach, I.
Genes & Development 19 (19): 2307-2319. 1 October 2005

Histone H3 tail positioning and acetylation by the c-Myb but not the v-Myb DNA-binding SANT domain.
Mo, X. and Kowenz-Leutz, E. and Laumonnier, Y. and Xu, H. and Leutz, A.
Genes & Development 19 (20): 2447-2457. 29 September 2005

CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells.
Vasyutina, E. and Stebler, J. and Brand-Saberi, B. and Schulz, S. and Raz, E. and Birchmeier, C.
Genes & Development 19 (18): 2187-2198. 15 September 2005

The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord.
Muller, T. and Anlag, K. and Wildner, H. and Britsch, S. and Treier, M. and Birchmeier, C.
Genes & Development 19 (6): 733-743. 1 January 2005

2004

Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
Brembeck, F.H. and Schwarz-Romond, T. and Bakkers, J. and Wilhelm, S. and Hammerschmidt, M. and Birchmeier, W.
Genes & Development 18 (18): 2225-2230. 15 September 2004

The MTE, a new core promoter element for transcription by RNA polymerase II.
Lim, C.Y. and Santoso, B. and Boulay, T. and Dong, E. and Ohler, U. and Kadonaga, J.T.
Genes & Development 18 (13): 1606-1617. 1 July 2004

2003

Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall.
Lindblom, P. and Gerhardt, H. and Liebner, S. and Abramsson, A. and Enge, M. and Hellstrom, M. and Backstrom, G. and Fredriksson, S. and Landegren, U. and Nystrom, H.C. and Bergstrom, G. and Dejana, E. and Ostman, A. and Lindahl, P. and Betsholtz, C.
Genes & Development 17 (15): 1835-1840. 1 August 2003

Translational control of SCL-isoform expression in hematopoietic lineage choice.
Calkhoven, C.F. and Mueller, C. and Martin, R. and Krosl, G. and Hoang, T. and Leutz, A.
Genes & Development 17 (8): 959-964. 15 April 2003

Genetic interaction between Wnt/β-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb.
Soshnikova, N. and Zechner, D. and Huelsken, J. and Mishina, Y. and Behringer, R.R. and Taketo, M.M. and Crenshaw, E.B. and Birchmeier, W.
Genes & Development 17 (16): 1963-1968. 1 January 2003

2002

Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis.
Ruhrberg, C. and Gerhardt, H. and Golding, M. and Watson, R. and Ioannidou, S. and Fujisawa, H. and Betsholtz, C. and Shima, D.T.
Genes & Development 16 (20): 2684-2698. 15 October 2002

The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling.
Schwarz-Romond, T. and Asbrand, C. and Bakkers, J. and Kuehl, M. and Schaeffer, H.J. and Huelsken, J. and Behrens, J. and Hammerschmidt, M. and Birchmeier, W.
Genes & Development 16 (16): 2073-2084. 15 August 2002

Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons.
Postigo, A. and Calella, A.M. and Fritzsch, B. and Knipper, M. and Katz, D. and Eilers, A. and Schimmang, T. and Lewin, G.R. and Klein, R. and Minichiello, L.
Genes & Development 16 (5): 633-645. 1 January 2002

Intronless homing: site-specific endonuclease SegF of bacteriophage T4 mediates localized marker exclusion analogous to homing endonucleases of group I introns.
Belle, A. and Landthaler, M. and Shub, D.A.
Genes & Development 16 (3): 351-362. 2002

WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase.
Su, F. and Overholtzer, M. and Besser, D. and Levine, A.J.
Genes & Development 16 (1): 46-57. 2002

2001

Activation of the Notch-regulated transcription factor CBF1/RBP-J kappa through the 13SE1A oncoprotein.
Ansieau, S. and Strobl, L.J. and Leutz, A.
Genes & Development 15 (4): 380-385. 1 January 2001

The transcription factor Sox10 is a key regulator of peripheral glial development.
Britsch, S. and Goerich, D.E. and Riethmacher, D. and Peirano, R.I. and Rossner, M. and Nave, K.A. and Birchmeier, C. and Wegner, M.
Genes & Development 15 (1): 66-78. 1 January 2001

Cooperation between C/EBP alphaTBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation.
Pedersen, T.A. and Kowenz-Leutz, E. and Leutz, A. and Nerlov, C.
Genes & Development 15 (21): 3208-3216. 1 January 2001

2000

Translational control of C/EBP alpha and C/EBP beta isoform expression.
Calkhoven, C.F. and Mueller, C. and Leutz, A.
Genes & Development 14 (15): 1920-1932. 1 August 2000

Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation.
Chen, C.Y. and Gherzi, R. and Andersen, J.S. and Gaietta, G. and Juerchott, K. and Royer, H.D. and Mann, M. and Karin, M.
Genes & Development 14 (10): 1236-1248. 15 May 2000

1999

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.
Schmitt, C.A. and McCurrach, M.E. and de Stanchina, E. and Wallace-Brodeur, R.R. and Lowe, S.W.
Genes & Development 13 (20): 2670-2677. 15 October 1999

Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development.
Woldeyesus, M.T. and Britsch, S. and Riethmacher, D. and Xu, L. and Sonnenberg-Riethmacher, E. and Abou-Rebyeh, F. and Harvey, R. and Caroni, P. and Birchmeier, C.
Genes & Development 13 : 2538-2548. 1 October 1999

Assembly of functionally active Drosophila origin recognition complex from recombinant proteins.
Chesnokov, I. and Gossen, M. and Remus, D. and Botchan, M.
Genes & Development 13 : 1289-1296. 15 May 1999

1998

Distinct C/EBP functions are required for eosinophil lineage commitment and maturation.
Nerlov, C. and McNagny, K.M. and Doederlein, G. and Kowenz-Leutz, E. and Graf, T.
Genes & Development 12 (15): 2413-2423. 1 August 1998

The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system.
Britsch, S. and Li, L. and Kirchhoff, S. and Theuring, F. and Brinkmann, V. and Birchmeier, C. and Riethmacher, D.
Genes & Development 12 : 1825-1836. 1 January 1998

1996

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.
Johe, K.K. and Hazel, T.G. and Mueller, T. and Dugich-Djordjevic, M.M. and McKay, R.D.
Genes & Development 10 (24): 3129-3140. 15 December 1996

The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis.
Sonnenberg-Riethmacher, E. and Walter, B. and Riethmacher, D. and Goedecke, S. and Birchmeier, C.
Genes & Development 10 (10): 1184-1193. 1 January 1996

1994

Novel mechanism of C/EBPbeta (NF-M) transcriptional control: activation through derepression.
Kowenz-Leutz, E. and Twamley, G. and Ansieau, S. and Leutz, A.
Genes & Development 8 (22): 2781-2791. 15 November 1994

1993

Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell types.
Ness, S.A. and Kowenz-Leutz, E. and Casini, T. and Graf, T. and Leutz, A.
Genes & Development 7 (5): 749-759. May 1993

Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner.
Briegel, K. and Lim, K.C. and Plank, C. and Beug, H. and Engel, J.D. and Zenke, M.
Genes & Development 7 : 1097-1109. 1 January 1993

1992

Transcriptional regulation of the HIV-1 promoter by NF-kappa B in vitro.
Kretzschmar, M. and Meisterernst, M. and Scheidereit, C. and Li, G. and Roeder, R.G.
Genes & Development 6 (5): 761-774. May 1992