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2024

Cellular landscape of adrenocortical carcinoma at single-nuclei resolution.
Tourigny, D.S., Altieri, B., Secener, A.K., Sbiera, S., Schauer, M.P., Arampatzi, P., Herterich, S., Sauer, S., Fassnacht, M. and Ronchi, C.L.
Molecular and Cellular Endocrinology 590 : 112272. 1 September 2024

Single-nucleus and spatial transcriptome reveal adrenal homeostasis in normal and tumoural adrenal glands.
Altieri, B., Secener, A.K., Sai, S., Fischer, C., Sbiera, S., Arampatzi, P., Kircher, S., Herterich, S., Landwehr, L.S., Vitcetz, S.N., Braeuning, C., Fassnacht, M., Ronchi, C.L. and Sauer, S.
Clinical and Translational Medicine 14 (8): e1798. August 2024

Interferon regulatory factor 4 plays a pivotal role in the development of aGVHD-associated colitis.
Frueh, J.T., Campe, J., Sunaga-Franze, D.Y., Verheyden, N.A., Ghimire, S., Meedt, E., Haslinger, D., Harenkamp, S., Staudenraus, D., Sauer, S., Kreft, A., Schubert, R., Lohoff, M., Krueger, A., Bonig, H., Chiocchetti, A.G., Zeiser, R., Holler, E. and Ullrich, E.
OncoImmunology 13 (1): 2296712. 2024

2023

A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation.
Vallecillo-García, P., Orgeur, M., Comai, G., Poehle-Kronnawitter, S., Fischer, C., Gloger, M., Dumas, C.E., Giesecke-Thiel, C., Sauer, S., Tajbakhsh, S., Höpken, U.E. and Stricker, S.
Immunity 56 (6): 1204-1219. 13 June 2023

Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González, R., Conrad, T., Stöber, M.C., Xu, R., Giurgiu, M., Rodriguez-Fos, E., Kasack, K., Brückner, L., van Leen, E., Helmsauer, K., Dorado Garcia, H., Stefanova, M.E., Hung, K.L., Bei, Y., Schmelz, K., Lodrini, M., Mundlos, S., Chang, H.Y., Deubzer, H.E., Sauer, S., Eggert, A., Schulte, J.H., Schwarz, R.F., Haase, K., Koche, R.P. and Henssen, A.G.
Nature Genetics 55 (5): 880-890. May 2023

2022

Regional gene expression patterns are associated with task-specific brain activation during reward and emotion processing measured with functional MRI.
Komorowski, A., Murgaš, M., Vidal, R., Singh, A., Gryglewski, G., Kasper, S., Wiltfang, J., Lanzenberger, R. and Goya-Maldonado, R.
Human Brain Mapping 43 (17): 5266-5280. 1 December 2022

Urbanization promotes specific bacteria in freshwater microbiomes including potential pathogens.
Numberger, D., Zoccarato, L., Woodhouse, J., Ganzert, L., Sauer, S., García Márquez, J.R., Domisch, S., Grossart, H.P. and Greenwood, A.D.
Science of the Total Environment 845 : 157321. 1 November 2022

Transcriptome analysis reveals putative genes involved in the lipid metabolism of chaulmoogra oil biosynthesis in Carpotroche brasiliensis (Raddi) A.Gray, a tropical tree species.
Vasconcelos, L.M., Bittencourt, F., Vidal, R.O., Silva, E.M.A., Costa, E.A., Micheli, F., Kirst, M., Pirovani, C.P. and Gaiotto, F.A
Forests 13 (11): 1806. 29 October 2022

Nonproductive exposure of PBMCs to SARS‐CoV ‐2 induces cell‐intrinsic innate immune responses.
Kazmierski, J., Friedmann, K., Postmus, D., Emanuel, J., Fischer, C., Jansen, J., Richter, A., Bosquillon de Jarcy, L., Schüler, C., Sohn, M., Sauer, S., Drosten, C., Saliba, A.E., Sander, L.E., Müller, M.A., Niemeyer, D. and Goffinet, C.
Molecular Systems Biology 18 (8): e10961. 1 August 2022

EBAG9 controls CD8(+) T cell memory formation responding to tumor challenge in mice.
Rehm, A., Wirges, A., Hoser, D., Fischer, C., Herda, S., Gerlach, K., Sauer, S., Willimsky, G. and Hoepken, U.E.
JCI Insight 7 (11): e155534. 8 June 2022

The transcription factor EB (TFEB) sensitizes the heart to chronic pressure overload.
Wundersitz, S., Pablo Tortola, C., Schmidt, S., Oliveira Vidal, R., Kny, M., Hahn, A., Zanders, L., Katus, H.A., Sauer, S., Butter, C., Luft, F.C., Müller, O.J. and Fielitz, J.
International Journal of Molecular Sciences 23 (11): 5943. 25 May 2022

Generation of hiPSC-derived skeletal muscle cells: exploiting the potential of skeletal muscle-derived hiPSCs.
Metzler, E., Escobar, H., Sunaga-Franze, D.Y., Sauer, S., Diecke, S. and Spuler, S.
Biomedicines 10 (5): 1204. 23 May 2022

Mammalian splicing divergence is shaped by drift, buffering in trans, and a scaling law.
Zou, X., Schaefke, B., Li, Y., Jia, F., Sun, W., Li, G., Liang, W., Reif, T., Heyd, F., Gao, Q., Tian, S., Li, Y., Tang, Y., Fang, L., Hu, Y. and Chen, W.
Life Science Alliance 5 (4): e202101333. April 2022

BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.
Kapalczynska, M., Lin, M., Maertzdorf, J., Heuberger, J., Muellerke, S., Zuo, X., Vidal, R., Shureiqi, I., Fischer, A.S., Sauer, S., Berger, H., Kidess, E., Mollenkopf, H.J., Tacke, F., Meyer, T.F. and Sigal, M.
Nature Communications 13 (1): 1577. 24 March 2022

Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Smajić, S., Prada-Medina, C.A., Landoulsi, Z., Ghelfi, J., Delcambre, S., Dietrich, C., Jarazo, J., Henck, J., Balachandran, S., Pachchek, S., Morris, C.M., Antony, P., Timmermann, B., Sauer, S., Pereira, S.L., Schwamborn, J.C., May, P., Grünewald, A. and Spielmann, M.
Brain 145 (3): 964-978. March 2022

2021

Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and aging.
Freitag, K., Eede, P., Ivanov, A., Schneeberger, S., Borodina, T., Sauer, S., Beule, D. and Heppner, F.L.
bioRxiv : 2021.08.02.454573v1. 28 November 2021

GAS1 is required for Notch-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.
Marczenke, M., Sunaga, D., Popp, O., Althaus, I.W., Sauer, S., Mertins, P., Christ, A., Allen, B.L. and Willnow, T.E.
Development 148 (21): dev200080. 11 November 2021

Single-nuclei RNA-sequencing of plant tissues using a nanowell-based system.
Sunaga-Franze, D., Muino, J.M., Braeuning, C., Xu, X., Zong, M., Smaczniak, C., Yan, W., Fischer, C., Vidal, R., Kliem, M., Kaufmann, K. and Sauer, S.
Plant Journal 108 (3): 859-869. 5 November 2021

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J., Grinat, J., Kosel, F., Liu, L., Kunz, S., Vidal, R.O., Keil, M., Haybaeck, J., Robine, S., Louvard, D., Regenbrecht, C., Sporbert, A., Sauer, S., von Eyss, B., Sigal, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 118 (22): e2019699118. 1 June 2021

Maternal angiotensin increases placental leptin in early gestation via an alternative renin-angiotensin system pathway: suggesting a link to preeclampsia.
Nonn, O., Fischer, C., Geisberger, S., El-Heliebi, A., Kroneis, T., Forstner, D., Desoye, G., Staff, A.C., Sugulle, M., Dechend, R., Pecks, U., Kollmann, M., Stern, C., Cartwright, J.E., Whitley, G.S., Thilaganathan, B., Wadsack, C., Huppertz, B., Herse, F. and Gauster, M.
Hypertension 77 (5): 1723-1736. May 2021

Transcriptome of iPSC-derived neuronal cells reveals a module of co-expressed genes consistently associated with autism spectrum disorder.
Griesi-Oliveira, K., Fogo, M.S., Pinto, B.G.G., Alves, A.Y., Suzuki, A.M., Morales, A.G., Ezquina, S., Sosa, O.J., Sutton, G.J., Sunaga-Franze, D.Y., Bueno, A.P., Seabra, G., Sardinha, L., Costa, S.S., Rosenberg, C., Zachi, E.C., Sertie, A.L., Martins-de-Souza, D., Reis, E.M., Voineagu, I. and Passos-Bueno, M.R.
Molecular Psychiatry 26 (5): 1589-1605. May 2021

The neuroinflammatory interleukin-12 signaling pathway drives Alzheimer's disease-like pathology by perturbing oligodendrocyte survival and neuronal homeostasis.
Schneeberger, S., Kim, S.J., Eede, P., Boltengagen, A., Braeuning, C., Andreadou, M., Becher, B., Karaiskos, N., Kocks, C., Rajewsky, N. and Heppner, F.L.
bioRxiv : 2021.04.25.441313. 27 April 2021

Dissecting herpes simplex virus 1-induced host shutoff at the RNA level.
Friedel, C.C., Whisnant, A.W., Djakovic, L., Rutkowski, A.J., Friedl, M.S., Kluge, M., Williamson, J.C., Sai, S., Vidal, R.O., Sauer, S., Hennig, T., Grothey, A., Milić, A., Prusty, B.K., Lehner, P.J., Matheson, N.J., Erhard, F. and Dölken, L.
Journal of Virology 95 (3): e01399-20. 13 January 2021

2020

The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Grinat, J., Heuberger, J., Vidal, R., Goveas, N., Kosel, F., Berenguer-Llergo, A., Kranz, A., Wulf-Goldenberg, A., Behrens, D., Melcher, B., Sauer, S., Vieth, M., Batlle, E., Stewart, A. and Birchmeier, W.
Nature Communications 11 (1): 6422. 21 December 2020

RNA-sequencing and somatic mutation status of adrenocortical tumors: novel pathogenetic insights.
Di Dalmazi, G., Altieri, B., Scholz, C., Sbiera, S., Luconi, M., Waldman, J., Kastelan, D., Ceccato, F., Chiodini, I., Arnaldi, G., Riester, A., Osswald, A., Beuschlein, F., Sauer, S., Fassnacht, M., Appenzeller, S. and Ronchi, C.L.
Journal of Clinical Endocrinology & Metabolism 105 (12): dgaa616. December 2020

The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization.
Daniel, B., Czimmerer, Z., Halasz, L., Boto, P., Kolostyak, Z., Poliska, S., Berger, W.K., Tzerpos, P., Nagy, G., Horvath, A., Hajas, G., Cseh, T., Nagy, A., Sauer, S., Francois-Deleuze, J., Szatmari, I., Bacsi, A. and Nagy, L.
Genes & Development 34 (21-22): 1474-1492. 1 November 2020

Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing.
Conrad, T., Ntini, E., Lang, B., Cozzuto, L., Andersen, J.B., Marquardt, J.U., Ponomarenko, J., Tartaglia, G.G. and Vang Orom, U.A.
RNA 26 (11): 1726-1730. November 2020

Intestinal expression of toll-like receptor gene changes early after gastric bypass surgery and association with type 2 diabetes remission.
Sala, P., Torrinhas, R.S.M.M., Fonseca, D.C., Machado, N.M., Singer, J., Singer, P., Ravacci, G.R., Belarmino, G., Ferreira, B.A.M., Marques, M., Ishida, R.K., Guarda, I.F.M.S., de Moura, E.G.H., Sakai, P., Santo, M.A., Sunaga, D.Y., Heymsfield, S.B., Bezerra, D.P.D.S., Corrêa-Giannella, M.L. and Waitzberg, D.L.
Nutrition 79-80 : 110885. November 2020

The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models.
Klems, A., van Rijssel, J., Ramms, A.S., Wild, R., Hammer, J., Merkel, M., Derenbach, L., Préau, L., Hinkel, R., Suarez-Martinez, I., Schulte-Merker, S., Vidal, R., Sauer, S., Kivelä, R., Alitalo, K., Kupatt, C., van Buul, J.D. and le Noble, F.
Nature Communications 11 (1): 5319. 21 October 2020

Viral cGAMP nuclease reveals the essential role of DNA sensing in protection against acute lethal virus infection.
Hernáez, B., Alonso, G., Georgana, I., El-Jesr, M., Martín, R., Shair, K.H.Y., Fischer, C., Sauer, S., Maluquer de Motes, C. and Alcamí, A.
Science Advances 6 (38): eabb4565. 18 September 2020

Resolving fates and single-cell transcriptomes of hematopoietic stem cell clones by PolyloxExpress barcoding.
Pei, W., Shang, F., Wang, X., Fanti, A.K., Greco, A., Busch, K., Klapproth, K., Zhang, Q., Quedenau, C., Sauer, S., Feyerabend, T.B., Höfer, T. and Rodewald, H.R.
Cell Stem Cell 27 (3): 383-395. 3 September 2020

Comparative analysis of the secretome and interactome of Trypanosoma cruzi and Trypanosoma rangeli reveals species specific immune response modulating proteins.
Watanabe Costa, R., Batista, M.F., Meneghelli, I., Vidal, R.O., Nájera, C.A., Mendes, A.C., Andrade-Lima, I.A., da Silveira, J.F., Lopes, L.R., Ferreira, L.R.P., Antoneli, F. and Bahia, D.
Frontiers in Immunology 11 : 1774. 27 August 2020

Maximizing transcription of nucleic acids with efficient T7 promoters.
Conrad, T., Plumbom, I., Alcobendas, M., Vidal, R. and Sauer, S.
Communications Biology 3 (1): 439. 14 August 2020

Splicing-accessible coding 3'UTRs control protein stability and interaction networks.
Preussner, M., Gao, Q., Morrison, E., Herdt, O., Finkernagel, F., Schumann, M., Krause, E., Freund, C., Chen, W. and Heyd, F.
Genome Biology 21 (1): 186. 29 July 2020

Regional expression profiles of risk genes for depression are associated with brain activation patterns in emotion and reward tasks.
Komorowski, A., Vidal, R., Singh, A., Murgaš, M., Pena-Centeno, T., Gryglewski, G., Kasper, S., Wiltfang, J., Lanzenberger, R. and Goya-Maldonado, R.
bioRxiv : 2020.06.27.175257. 27 June 2020

Benchmarking single-cell RNA-sequencing protocols for cell atlas projects.
Mereu, E., Lafzi, A., Moutinho, C., Ziegenhain, C., McCarthy, D.J., Álvarez-Varela, A., Batlle, E., Sagar, Grün, D., Lau, J.K., Boutet, S.C., Sanada, C., Ooi, A., Jones, R.C., Kaihara, K., Brampton, C., Talaga, Y., Sasagawa, Y., Tanaka, K., Hayashi, T., Braeuning, C., Fischer, C., Sauer, S., Trefzer, T., Conrad, C., Adiconis, X., Nguyen, L.T., Regev, A., Levin, J.Z., Parekh, S., Janjic, A., Wange, L.E., Bagnoli, J.W., Enard, W., Gut, M., Sandberg, R., Nikaido, I., Gut, I., Stegle, O. and Heyn, H.
Nature Biotechnology 38 (6): 747-755. June 2020

Prostaglandin E(2) in a TLR3- and 7/8-agonist-based DC maturation cocktail generates mature, cytokine-producing, migratory DCs but impairs antigen cross-presentation to CD8(+) T cells.
Gierlich, P., Lex, V., Technau, A., Keupp, A., Morper, L., Glunz, A., Sennholz, H., Rachor, J., Sauer, S., Marcu, A., Grigoleit, G.U., Wölfl, M., Schlegel, P.G. and Eyrich, M.
Cancer Immunology Immunotherapy 69 (6): 1029-1042. June 2020

Dissecting HSV-1-induced host shut-off at RNA level.
Friedel, C.C., Whisnant, A.W., Djakovic, L., Rutkowski, A.J., Friedl, M.S., Kluge, M., Williamson, J.C., Sai, S., Oliveira Vidal, R., Sauer, S., Hennig, T., Prusty, B., Lehner, P.J., Matheson, N.J., Erhard, F. and Dölken, L.
bioRxiv : 2020.05.20.106039. 20 May 2020

Single cell RNA-sequencing-based analysis of CD4(+) T-cell subset-specific susceptibility to transcriptional modulation by HIV-1 latency-reversing agents.
Kazmierski, J., Postmus, D., Wyler, E., Fischer, C., Jansen, J., Meixenberger, K., Vitcetz, S.N., Sohn, M., Sauer, S., Bannert, N., Landthaler, M. and Goffinet, C.
bioRxiv : 2020.05.04.075119. 5 May 2020

CRISPLD1: a novel conserved target in the transition to human heart failure.
Khadjeh, S., Hindmarsh, V., Weber, F., Cyganek, L., Vidal, R.O., Torkieh, S., Streckfuss-Bömeke, K., Lbik, D., Tiburcy, M., Mohamed, B.A., Bonn, S., Toischer, K. and Hasenfuss, G.
Basic Research in Cardiology 115 (3): 27. 7 March 2020

Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M., Fischer, C., Urzi, A., Vidal, R., Kunz, S., Ruffault, P.L., Kabuss, L., Hube, I., Gazzerro, E., Birchmeier, C., Spuler, S., Sauer, S. and Gouti, M.
Cell Stem Cell 26 (2): 172-186. 6 February 2020

Effects of diets high in animal or plant protein on oxidative stress in individuals with type 2 diabetes: a randomized clinical trial.
Pivovarova-Ramich, O., Markova, M., Weber, D., Sucher, S., Hornemann, S., Rudovich, N., Raila, J., Sunaga-Franze, D., Sauer, S., Rohn, S., Pfeiffer, A.F.H. and Grune, T.
Redox Biology 29 (2): 101397. January 2020

Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Koche, R.P., Rodriguez-Fos, E., Helmsauer, K., Burkert, M., MacArthur, I.C., Maag, J., Chamorro, R., Munoz-Perez, N., Puiggròs, M., Dorado Garcia, H., Bei, Y., Röefzaad, C., Bardinet, V., Szymansky, A., Winkler, A., Thole, T., Timme, N., Kasack, K., Fuchs, S., Klironomos, F., Thiessen, N., Blanc, E., Schmelz, K., Künkele, A., Hundsdörfer, P., Rosswog, C., Theissen, J., Beule, D., Deubzer, H., Sauer, S., Toedling, J., Fischer, M., Hertwig, F., Schwarz, R.F., Eggert, A., Torrents, D., Schulte, J.H. and Henssen, A.G.
Nature Genetics 52 (1): 29-34. January 2020

Organ-specific small non-coding RNA responses in domestic (Sudani) ducks experimentally infected with highly pathogenic avian influenza virus (H5N1).
Samir, M., Vidal, R.O., Abdallah, F., Capece, V., Seehusen, F., Geffers, R., Hussein, A., Ali, A.A.H., Bonn, S. and Pessler, F.
RNA Biology 17 (1): 112-124. January 2020

2019

Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.
Marg, A., Escobar Fernandez, H., Karaiskos, N., Grunwald, S.A., Metzler, E., Kieshauer, J., Sauer, S., Pasemann, D., Malfatti, E., Mompoint, D., Quijano-Roy, S., Boltengagen, A., Schneider, J., Schülke, M., Kunz, S., Carlier, R., Birchmeier, C., Amthor, H., Spuler, A., Kocks, C., Rajewsky, N. and Spuler, S.
Nature Communications 10 (1): 5776. 18 December 2019

Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart.
Vidal, R., Wagner, J.U.G., Braeuning, C., Fischer, C., Patrick, R., Tombor, L., Muhly-Reinholz, M., John, D., Kliem, M., Conrad, T., Guimarães-Camboa, N., Harvey, R., Dimmeler, S. and Sauer, S.
JCI Insight 4 (22): e131092. 14 November 2019

Long and repeat-rich intronic sequences favor circular RNA formation under conditions of reduced spliceosome activity.
Wang, M., Hou, J., Müller-McNicoll, M., Chen, W. and Schuman, E.M.
iScience 20 : 237-247. 25 October 2019

R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.
Harnack, C., Berger, H., Antanaviciute, A., Vidal, R., Sauer, S., Simmons, A., Meyer, T.F. and Sigal, M.
Nature Communications 10 (1): 4368. 25 September 2019

Clonality of circulating tumor cells in breast cancer brain metastasis patients.
Riebensahm, C., Joosse, S.A., Mohme, M., Hanssen, A., Matschke, J., Goy, Y., Witzel, I., Lamszus, K., Kropidlowski, J., Petersen, C., Kolb-Kokocinski, A., Sauer, S., Borgmann, K., Glatzel, M., Müller, V., Westphal, M., Riethdorf, S., Pantel, K. and Wikman, H.
Breast Cancer Research and Treatment 21 (1): 101. 3 September 2019

Characterization of bacterial communities in wastewater with enhanced taxonomic resolution by full-length 16S rRNA sequencing.
Numberger, D., Ganzert, L., Zoccarato, L., Mühldorfer, K., Sauer, S., Grossart, H.P. and Greenwood, A.D.
Scientific Reports 9 (1): 9673. 4 July 2019

R-spondin-3 induces secretory, antimicrobial Lgr5(+) cells in the stomach.
Sigal, M., Del Mar Reinés, M., Müllerke, S., Fischer, C., Kapalczynska, M., Berger, H., Bakker, E.R.M., Mollenkopf, H.J., Rothenberg, M.E., Wiedenmann, B., Sauer, S. and Meyer, T.F.
Nature Cell Biology 21 (7): 812-823. July 2019

Signals trigger state-specific transcriptional programs to support diversity and homeostasis in immune cells.
Fischer, C., Metsger, M., Bauch, S., Vidal, R., Böttcher, M., Grote, P., Kliem, M. and Sauer, S.
Science Signaling 12 (581): eaao5820. 14 May 2019

HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M., Yu, Y., Liang, L., Vuralli, D., Froehler, S., Kuehnen, P., Du Bois, P., Zhang, J., Cao, A., Liu, Y., Hussain, K., Fielitz, J., Jia, S., Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7 (5): e602. May 2019

Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined.
Kaleviste, E., Saare, M., Leahy, T.R., Bondet, V., Duffy, D., Mogensen, T., Jørgensen, S.E., Nurm, H., Ip, W., Davies, E.G., Sauer, S., Syvänen, A.C., Milani, L., Peterson, P. and Kisand, K.
European Journal of Immunology 49 (5): 790-800. May 2019

Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma.
Haage, V., Semtner, M., Oliveira Vidal, R., Perez Hernandez, D., Pong, W.W., Chen, Z., Hambardzumyan, D., Magrini, V., Ly, A., Walker, J., Mardis, E., Mertins, P., Sauer, S., Kettenmann, H. and Gutmann, D.H.
Acta Neuropathologica Communications 7 (1): 20. 14 February 2019

The Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer.
Zhu, Q., Fang, L., Heuberger, J., Kranz, A., Schipper, J., Scheckenbach, K., Oliveira Vidal, R., Sunaga-Franze, D.Y., Müller, M., Wulf-Goldenberg, A., Sauer, S. and Birchmeier, W.
Cell Reports 26 (2): 415-428. 8 January 2019

2018

A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding.
Hernáez, B., Alonso-Lobo, J.M., Montanuy, I., Fischer, C., Sauer, S., Sigal, L., Sevilla, N. and Alcamí, A.
Nature Communications 9 (1): 5440. 21 December 2018

Chromatin accessibility dynamics across C. elegans development and ageing.
Jänes, J., Dong, Y., Schoof, M., Serizay, J., Appert, A., Cerrato, C., Woodbury, C., Chen, R., Gemma, C., Huang, N., Kissiov, D., Stempor, P., Steward, A., Zeiser, E., Sauer, S. and Ahringer, J.
eLife 7 : e37344. 26 October 2018

The nuclear receptor PPARγ controls progressive macrophage polarization as a ligand-insensitive epigenomic ratchet of transcriptional memory.
Daniel, B., Nagy, G., Czimmerer, Z., Horvath, A., Hammers, D.W., Cuaranta-Monroy, I., Poliska, S., Tzerpos, P., Kolostyak, Z., Hays, T.T., Patsalos, A., Houtman, R., Sauer, S., Francois-Deleuze, J., Rastinejad, F., Balint, B.L., Sweeney, H.L. and Nagy, L.
Immunity 49 (4): 615-626. 16 October 2018

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages.
Czimmerer, Z., Nagy, Z.S., Nagy, G., Horvath, A., Silye-Cseh, T., Kriston, A., Jonas, D., Sauer, S., Steiner, L., Daniel, B., Deleuze, J.F. and Nagy, L.
Molecular and Cellular Endocrinology 471 : 63-74. 15 August 2018

RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification.
Simandi, Z., Horvath, A., Cuaranta-Monroy, I., Sauer, S., Deleuze, J.F. and Nagy, L.
Molecular and Cellular Endocrinology 471 : 51-62. 15 August 2018

Transient N-6-methyladenosine transcriptome sequencing reveals a regulatory role of m6A in splicing efficiency.
Louloupi, A., Ntini, E., Conrad, T. and Ørom, U.A.V.
Cell Reports 23 (12): 3429-3437. 19 June 2018

Loss of the hematopoietic stem cell factor GATA2 in the osteogenic lineage impairs trabecularization and mechanical strength of bone.
Tolkachov, A., Fischer, C., Ambrosi, T.H., Bothe, M., Han, C.T., Muenzner, M., Mathia, S., Salminen, M., Seifert, G., Thiele, M., Duda, G.N., Meijsing, S.H., Sauer, S., Schulz, T.J. and Schupp, M.
Molecular and Cellular Biology 38 (12): e00599-17. June 2018

The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages.
Daniel, B., Nagy, G., Horvath, A., Czimmerer, Z., Cuaranta-Monroy, I., Poliska, S., Hays, T.T., Sauer, S., Francois-Deleuze, J. and Nagy, L.
Nucleic Acids Research 46 (9): 4425-4439. 18 May 2018

Faecal microbiota composition associates with abdominal pain in the general population.
Hadizadeh, F., Bonfiglio, F., Belheouane, M., Vallier, M., Sauer, S., Bang, C., Bujanda, L., Andreasson, A., Agreus, L., Engstrand, L., Talley, N.J., Rafter, J., Baines, J.F., Walter, S., Franke, A. and D'Amato, M.
Gut 67 (4): 778-779. 8 March 2018

De novo mutations implicate novel genes in systemic lupus erythematosus.
Pullabhatla, V., Roberts, A.L., Lewis, M.J., Mauro, D., Morris, D.L., Odhams, C.A., Tombleson, P., Liljedahl, U., Vyse, S., Simpson, M.A., Sauer, S., de Rinaldis, E., Syvänen, A.C. and Vyse, T.J.
Human Molecular Genetics 27 (3): 421-429. 1 February 2018

The transcription factor STAT6 mediates direct repression of inflammatory enhancers and limits activation of alternatively polarized macrophages.
Czimmerer, Z., Daniel, B., Horvath, A., Rückerl, D., Nagy, G., Kiss, M., Peloquin, M., Budai, M.M., Cuaranta-Monroy, I., Simandi, Z., Steiner, L., Nagy, B., Poliska, S., Banko, C., Bacso, Z., Schulman, I.G., Sauer, S., Deleuze, J.F., Allen, J.E., Benko, S. and Nagy, L.
Immunity 48 (1): 75-90. 16 January 2018

Perturbation-response genes reveal signaling footprints in cancer gene expression.
Schubert, M., Klinger, B., Klünemann, M., Sieber, A., Uhlitz, F., Sauer, S., Garnett, M.J., Blüthgen, N. and Saez-Rodriguez, J.
Nature Communications 9 (1): 20. 2 January 2018

2017

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.
Pei, W., Feyerabend, T.B., Rössler, J., Wang, X., Postrach, D., Busch, K., Rode, I., Klapproth, K., Dietlein, N., Quedenau, C., Chen, W., Sauer, S., Wolf, S., Höfer, T. and Rodewald, H.Re.
Nature 548 (7668): 456-460. 24 August 2017

Signatures of personality on dense 3D facial images.
Hu, S., Xiong, J., Fu, P., Qiao, L., Tan, J., Jin, L. and Tang, K.
Scientific Reports 7 (1): 73. March 2017

RNA-seq based transcriptome analysis of the type I interferon host response upon vaccinia virus infection of mouse cells.
Hernáez, B., Alonso, G., Alonso-Lobo, J.M., Rastrojo, A., Fischer, C., Sauer, S., Aguado, B. and Alcamí, A.
Journal of Immunology Research 2017 : 5157626. 9 February 2017

Health-beneficial nutraceuticals - myth or reality?
Sauer, S. and Plauth, A.
Applied Microbiology and Biotechnology 101 (3): 951-961. February 2017

2016

Data of oxygen- and pH-dependent oxidation of resveratrol.
Plauth, A., Geikowski, A., Cichon, S., Wowro, S.J., Liedgens, L., Rousseau, M., Weidner, C., Fuhr, L., Kliem, M., Jenkins, G., Lotito, S., Wainwright, L.J. and Sauer, S.
Data in Brief 9 : 433-437. December 2016

The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery.
Stunnenberg, H.G. and Hirst, M.
Cell 167 (7): 1145-1149. 17 November 2016

Efficient application of de novo RNA assemblers for proteomics informed by transcriptomics.
Luge, T., Fischer, C. and Sauer, S.
Journal of Proteome Research 15 (10): 3938-3943. 7 October 2016

Dissecting the effect of genetic variation on the hepatic expression of drug disposition genes across the collaborative cross mouse strains.
Nachshon, A., Abu-Toamih Atamni, H.J., Steuerman, Y., Sheikh-Hamed, R., Dorman, A., Mott, R., Dohm, J.C., Lehrach, H., Sultan, M., Shamir, R., Sauer, S., Himmelbauer, H., Iraqi, F.A. and Gat-Viks, I.
Frontiers in Genetics 7 : 172. 5 October 2016

Hormetic shifting of redox environment by pro-oxidative resveratrol protects cells against stress.
Plauth, A., Geikowski, A., Cichon, S., Wowro, S.J., Liedgens, L., Rousseau, M., Weidner, C., Fuhr, L., Kliem, M., Jenkins, G., Lotito, S., Wainwright, L.J. and Sauer, S.
Free Radical Biology and Medicine 99 : 608-622. October 2016

OCT4 acts as an integrator of pluripotency and signal-induced differentiation.
Simandi, Z., Horvath, A., Wright, L.C., Cuaranta-Monroy, I., De Luca, I., Karolyi, K., Sauer, S., Deleuze, J.F., Gudas, L.J., Cowley, S.M. and Nagy, L.
Molecular Cell 63 (4): 647-661. 18 August 2016

TTC25 deficiency results in defects of the outer dynein arm docking machinery and primary ciliary dyskinesia with left-right body asymmetry randomization.
Wallmeier, J., Shiratori, H., Dougherty, G.W., Edelbusch, C., Hjeij, R., Loges, N.T., Menchen, T., Olbrich, H., Pennekamp, P., Raidt, J., Werner, C., Minegishi, K., Shinohara, K., Asai, Y., Takaoka, K., Lee, C., Griese, M., Memari, Y., Durbin, R., Kolb-Kokocinski, A., Sauer, S., Wallingford, J.B., Hamada, H. and Omran, H.
American Journal of Human Genetics 99 (2): 460-469. 4 August 2016

A novel splicing mutation in the IQSEC2 gene that modulates the phenotype severity in a family with intellectual disability.
Madrigal, I., Alvarez-Mora, M.I., Rosell, J., Rodríguez-Revenga, L., Karlberg, O., Sauer, S., Syvänen, A.C. and Mila, M.
European Journal of Human Genetics 24 (8): 1117-1123. August 2016

Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements.
Telorac, J., Prykhozhij, S.V., Schöne, S., Meierhofer, D., Sauer, S., Thomas-Chollier, M. and Meijsing, S.H.
Nucleic Acids Research 44 (13): 6142-6156. 27 July 2016

Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3.
Van Haute, L., Dietmann, S., Kremer, L., Hussain, S., Pearce, S.F., Powell, C.A., Rorbach, J., Lantaff, R., Blanco, S., Sauer, S., Kotzaeridou, U., Hoffmann, G.F., Memari, Y., Kolb-Kokocinski, A., Durbin, R., Mayr, J.A., Frye, M., Prokisch, H. and Minczuk, M.
Nature Communications 7 : 12039. 30 June 2016

The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation.
Vučićević, D., Gehre, M., Dhamija, S., Friis-Hansen, L., Meierhofer, D., Sauer, S. and Ørom, U.A.
Oncotarget 7 (23): 33934-33947. 7 June 2016

New technologies for DNA analysis - a review of the READNA project.
McGinn, S., Bauer, D., Brefort, T., Dong, L., El-Sagheer, A., Elsharawy, A., Evans, G., Falk-Sörqvist, E., Forster, M., Fredriksson, S., Freeman, P., Freitag, C., Fritzsche, J., Gibson, S., Gullberg, M., Gut, M., Heath, S., Heath-Brun, I., Heron, A.J., Hohlbein, J., Ke, R., Lancaster, O., Le Reste, L., Maglia, G., Marie, R., Mauger, F., Mertes, F., Mignardi, M., Moens, L., Oostmeijer, J., Out, R., Pedersen, J.N., Persson, F., Picaud, V., Rotem, D., Schracke, N., Sengenes, J., Stähler, P.F., Stade, B., Stoddart, D., Teng, X., Veal, C.D., Zahra, N., Bayley, H., Beier, M., Brown, T., Dekker, C., Ekström, B., Flyvbjerg, H., Franke, A., Guenther, S., Kapanidis, A.N., Kaye, J., Kristensen, A., Lehrach, H., Mangion, J., Sauer, S., Schyns, E., Tost, J., van Helvoort, J.M.L.M., van der Zaag, P.J., Tegenfeldt, J.O., Brookes, A.J., Mir, K., Nilsson, M., Willcocks, J.P. and Gut, I.G.
New Biotechnology 33 (3): 311-330. 25 May 2016

Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA.
Cui, H., Schlesinger, J., Schoenhals, S., Toenjes, M., Dunkel, I., Meierhofer, D., Cano, E., Schulz, K., Berger, M.F., Haack, T., Abdelilah-Seyfried, S., Bulyk, M.L., Sauer, S. and Sperling, S.R.
Nucleic Acids Research 44 (6): 2538-2553. 7 April 2016

Iberis amara extract induces intracellular formation of reactive oxygen species and inhibits colon cancer.
Weidner, C., Rousseau, M., Plauth, A., Wowro, S.J., Fischer, C., Abdel-Aziz, H. and Sauer, S.
PLoS ONE 11 (4): e0152398. 6 April 2016

Serial interactome capture of the human cell nucleus.
Conrad, T., Albrecht, A.-S., Rodrigues de Melo Costa, V., Sauer, S., Meierhofer, D. and Ørom, U.A.
Nature Communications 7 : 11212. 4 April 2016

Identification of novel genetic causes of Rett syndrome-like phenotypes.
Lopes, F., Barbosa, M., Ameur, A., Soares, G., de Sá, J., Dias, A.I., Oliveira, G., Cabral, P., Temudo, T., Calado, E., Cruz, I.F., Vieira, J.P., Oliveira, R., Esteves, S., Sauer, S., Jonasson, I., Syvänen, A.C., Gyllensten, U., Pinto, D. and Maciel, P.
Journal of Medical Genetics 53 (3): 190-199. March 2016

Bi-allelic truncating mutations in TANGO2 cause infancy-onset recurrent metabolic crises with encephalocardiomyopathy.
Kremer, L.S., Distelmaier, F., Alhaddad, B., Hempel, M., Iuso, A., Küpper, C., Mühlhausen, C., Kovacs-Nagy, R., Satanovskij, R., Graf, E., Berutti, R., Eckstein, G., Durbin, R., Sauer, S., Hoffmann, G.F., Strom, T.M., Santer, R., Meitinger, T., Klopstock, T., Prokisch, H. and Haack, T.B.
American Journal of Human Genetics 98 (2): 358-362. 4 February 2016

Analysis of genes involved in body weight regulation by targeted re-sequencing.
Volckmar, A.L., Han, C.T., Pütter, C., Haas, S., Vogel, C.I.G., Knoll, N., Struve, C., Göbel, M., Haas, K., Herrfurth, N., Jarick, I., Grallert, H., Schürmann, A., Al-Hasani, H., Hebebrand, J., Sauer, S. and Hinney, A.
PLoS ONE 11 (2): e0147904. 1 February 2016

Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease patients reveals changes in genes associated with T cell receptor signaling.
Limbach, M., Saare, M., Tserel, L., Kisand, K., Eglit, T., Sauer, S., Axelsson, T., Syvänen, A.C., Metspalu, A., Milani, L. and Peterson, P.
Journal of Autoimmunity 67 : 46-56. February 2016

Amorfrutin C induces apoptosis and inhibits proliferation in colon cancer cells through targeting mitochondria.
Weidner, C., Rousseau, M., Micikas, R.J., Fischer, C., Plauth, A., Wowro, S.J., Siems, K., Hetterling, G., Kliem, M., Schroeder, F.C. and Sauer, S.
Journal of Natural Products 79 (1): 2-12. 22 January 2016

Generating sample-specific databases for mass spectrometry-based proteomic analysis by using RNA sequencing.
Luge, T. and Sauer, S.
Methods in Molecular Biology 1394 : 219-232. 2016

2015

Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism.
Correia, J.C., Massart, J., de Boer, J.F., Porsmyr-Palmertz, M., Martínez-Redondo, V., Agudelo, L.Z., Sinha, I., Meierhofer, D., Ribeiro, V., Björnholm, M., Sauer, S., Dahlman-Wright, K., Zierath, J.R., Groen, A.K. and Ruas, J.L.
Molecular Metabolism 4 (12): 891-902. December 2015

Homozygous loss-of-function variants in european cosmopolitan and isolate populations.
Kaiser, V.B., Svinti, V., Prendergast, J.G., Chau, Y.Y., Campbell, A., Patarcic, I., Barroso, I., Joshi, P.K., Hastie, N.D., Miljkovic, A., Taylor, M.S., Enroth, S., Memari, Y., Kolb-Kokocinski, A., Wright, A.F., Gyllensten, U., Durbin, R., Rudan, I., Campbell, H., Polašek, O., Johansson, A., Sauer, S., Porteous, D.J., Fraser, R.M., Drake, C., Vitart, V., Hayward, C., Semple, C.A. and Wilson, J.F.
Human Molecular Genetics 24 (19): 5464-5474. 1 October 2015

Immunofluorescence analysis and diagnosis of primary ciliary dyskinesia with radial spoke defects.
Frommer, A., Hjeij, R., Loges, N.T., Edelbusch, C., Jahnke, C., Raidt, J., Werner, C., Wallmeier, J., Große-Onnebrink, J., Olbrich, H., Cindrić, S., Jaspers, M., Boon, M., Memari, Y., Durbin, R., Kolb-Kokocinski, A., Sauer, S., Marthin, J.K., Nielsen, K.G., Amirav, I., Elias, N., Kerem, E., Shoseyov, D., Haeffner, K. and Omran, H.
American Journal of Respiratory Cell and Molecular Biology 53 (4): 563-573. 1 October 2015

GORAB missense mutations disrupt RAB6 and ARF5 binding and golgi targeting.
Egerer, J., Emmerich, D., Fischer-Zirnsak, B., Chan, W.L., Meierhofer, D., Tuysuz, B., Marschner, K., Sauer, S., Barr, F.A., Mundlos, S. and Kornak, U.
Journal of Investigative Dermatology 135 (10): 2368-2376. October 2015

Ligands for the nuclear peroxisome proliferator-activated receptor gamma.
Sauer, S.
Trends in Pharmacological Sciences 36 (10): 688-704. October 2015

Development of a high-resolution NGS-based HLA-typing and analysis pipeline.
Wittig, M., Anmarkrud, J.A., Kässens, J.C., Koch, S., Forster, M., Ellinghaus, E., Hov, J.R., Sauer, S., Schimmler, M., Ziemann, M., Görg, S., Jacob, F., Karlsen, T.H. and Franke, A.
Nucleic Acids Research 43 (11): e70. 23 June 2015

Amorfrutins are natural PPARγ agonists with potent anti-inflammatory properties.
Fuhr, L., Rousseau, M., Plauth, A., Schroeder, F.C. and Sauer, S.
Journal of Natural Products 78 (5): 1160-1164. 22 May 2015

Deficiency of ECHS1 causes mitochondrial encephalopathy with cardiac involvement.
Haack, T.B., Jackson, C.B., Murayama, K., Kremer, L.S., Schaller, A., Kotzaeridou, U., de Vries, M.C., Schottmann, G., Santra, S., Büchner, B., Wieland, T., Graf, E., Freisinger, P., Eggimann, S., Ohtake, A., Okazaki, Y., Kohda, M., Kishita, Y., Tokuzawa, Y., Sauer, S., Memari, Y., Kolb-Kokocinski, A., Durbin, R., Hasselmann, O., Cremer, K., Albrecht, B., Wieczorek, D., Engels, H., Hahn, D., Zink, A.M., Alston, C.L., Taylor, R.W., Rodenburg, R.J., Trollmann, R., Sperl, W., Strom, T.M., Hoffmann, G.F., Mayr, J.A., Meitinger, T., Bolognini, R., Schuelke, M., Nuoffer, J.M., Kölker, S., Prokisch, H. and Klopstock, T.
Annals of Clinical and Translational Neurology 2 (5): 492-509. May 2015

Deep sequencing of the trypanosoma cruzi GP63 surface proteases reveals diversity and diversifying selection among chronic and congenital Chagas disease patients.
Llewellyn, M.S., Messenger, L.A., Luquetti, A.O., Garcia, L., Torrico, F., Tavares, S.B.N., Cheaib, B., Derome, N., Delepine, M., Baulard, C., Deleuze, J.F., Sauer, S. and Miles, M.A.
PLoS Neglected Tropical Diseases 9 (4): e0003458. 7 April 2015

Nutriproteomics: facts, concepts, and perspectives.
Sauer, S. and Luge, T.
Proteomics 15 (5-6): 997-1013. March 2015

PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology.
Simandi, Z., Czipa, E., Horvath, A., Koszeghy, A., Bordas, C., Póliska, S., Juhász, I., Imre, L., Szabó, G., Dezso, B., Barta, E., Sauer, S., Karolyi, K., Kovacs, I., Hutóczki, G., Bognár, L., Klekner, A., Szucs, P., Bálint, B.L. and Nagy, L.
Stem Cells 33 (3): 726-741. March 2015

Melissa officinalis extract induces apoptosis and inhibits proliferation in colon cancer cells through formation of reactive oxygen species.
Weidner, C., Rousseau, M., Plauth, A., Wowro, S.J., Fischer, C., Abdel-Aziz, H. and Sauer, S.
Phytomedicine 22 (2): 262-270. 15 February 2015

A common building block for the syntheses of amorfrutin and cajaninstilbene acid libraries toward efficient binding with peroxisome proliferator-activated receptors.
Aidhen, I.S., Mukkamala, R., Weidner, C. and Sauer, S.
Organic Letters 17 (2): 194-197. 16 January 2015

2014

Integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs.
Meierhofer, D., Weidner, C. and Sauer, S.
Journal of Proteome Research 13 (12): 5592-5602. 5 December 2014

PHOXTRACK-a tool for interpreting comprehensive datasets of post-translational modifications of proteins.
Weidner, C., Fischer, C. and Sauer, S.
Bioinformatics 30 (23): 3410-3411. 1 December 2014

Efficient application of next-generation sequencing for the diagnosis of rare genetic syndromes.
Madrigal, I., Alvarez-Mora, M.I., Karlberg, O., Rodríguez-Revenga, L., Elurbe, D.M., Rabionet, R., Mur, A., Pie, J., Ballesta, F., Sauer, S., Syvänen, A.C. and Milà, M.
Journal of Clinical Pathology 67 (12): 1099-1103. December 2014

Transcriptomics assisted proteomic analysis of Nicotiana occidentalis infected by Candidatus Phytoplasma mali strain AT.
Luge, T., Kube, M., Freiwald, A., Meierhofer, D., Seemüller, E. and Sauer, S.
Proteomics 14 (16): 1882-1889. August 2014

Relationship between genome and epigenome - challenges and requirements for future research.
Almouzni, G., Altucci, L., Amati, B., Ashley, N., Baulcombe, D., Beaujean, N., Bock, C., Bongcam-Rudloff, E., Bousquet, J., Braun, S., Bressac-de Paillerets, B., Bussemakers, M., Clarke, L., Conesa, A., Estivill, X., Fazeli, A., Grgurević, N., Gut, I., Heijmans, B.T., Hermouet, S., Houwing-Duistermaat, J., Iacobucci, I., Ilaš, J., Kandimalla, R., Krauss-Etschmann, S., Lasko, P., Lehmann, S., Lindroth, A., Majdič, G., Marcotte, E., Martinelli, G., Martinet, N., Meyer, E., Miceli, C., Mills, K., Moreno-Villanueva, M., Morvan, G., Nickel, D., Niesler, B., Nowacki, M., Nowak, J., Ossowski, S., Pelizzola, M., Pochet, R., Potočnik, U., Radwanska, M., Raes, J., Rattray, M., Robinson, M.D., Roelen, B., Sauer, S., Schinzer, D., Slagboom, E., Spector, T., Stunnenberg, H.G., Tiligada, E., Torres-Padilla, M.E., Tsonaka, R., Van Soom, A., Vidaković, M. and Widschwendter, M.
BMC Genomics 15 : 487. 18 June 2014

Amorfrutins: a promising class of natural products that are beneficial to health.
Sauer, S.
ChemBioChem 15 (9): 1231-1238. 16 June 2014

Analysis of expressed genes of the bacterium 'Candidatus Phytoplasma mali' highlights key features of virulence and metabolism.
Siewert, C., Luge, T., Duduk, B., Seemüller, E., Büttner, C., Sauer, S. and Kube, M.
PLOS ONE 9 (4): e94391. 11 April 2014

Lemon balm extract causes potent antihyperglycemic and antihyperlipidemic effects in insulin-resistant obese mice.
Weidner, C., Wowro, S.J., Freiwald, A., Kodelja, V., Abdel-Aziz, H., Kelber, O. and Sauer, S.
Molecular Nutrition & Food Research 58 (4): 903-907. April 2014

2013

Comprehensive proteomic data sets for studying adipocyte-macrophage cell-cell communication.
Freiwald, A., Weidner, C., Witzke, A., Huang, S.Y., Meierhofer, D. and Sauer, S.
Proteomics 13 (23-24): 3424-3428. December 2013

Diagnostic proteomics: will this impact the clinic?
Sauer, S.
Proteomics Clinical Applications 7 (11-12): 725-726. December 2013

Antidiabetic effects of chamomile flowers extract in obese mice through transcriptional stimulation of nutrient sensors of the peroxisome proliferator-activated receptor (PPAR) family.
Weidner, C., Wowro, S.J., Rousseau, M., Freiwald, A., Kodelja, V., Abdel-Aziz, H., Kelber, O. and Sauer, S.
PLOS ONE 8 (11): e80335. 12 November 2013

Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPARγ) agonist with potent glucose-lowering properties.
Weidner, C., Wowro, S.J., Freiwald, A., Kawamoto, K., Witzke, A., Kliem, M., Siems, K., Müller-Kuhrt, L., Schroeder, F.C. and Sauer, S.
Diabetologia 56 (8): 1802-1812. August 2013

Protein set analyses: how could this impact the clinic?
Sauer, S.
Expert Review of Proteomics 10 (4): 305-307. August 2013

Protein sets define disease states and predict in vivo effects of drug treatment.
Meierhofer, D., Weidner, C., Hartmann, L., Mayr, J.A., Han, C.T., Schroeder, F.C. and Sauer, S.
Molecular & Cellular Proteomics 12 (7): 1965-1979. 1 July 2013

Discovery and characterization of protein-modifying natural products by MALDI mass spectrometry reveal potent SIRT1 and p300 inhibitors.
Holzhauser, S., Freiwald, A., Weise, C., Multhaup, G., Han, C.T. and Sauer, S.
Angewandte Chemie International Edition 52 (19): 5171-5174. 3 May 2013

A Y2H-seq approach defines the human protein methyltransferase interactome.
Weimann, M., Grossmann, A., Woodsmith, J., Özkan, Z., Birth, P., Meierhofer, D., Benlasfer, N., Valovka, T., Timmermann, B., Wanker, E.E., Sauer, S. and Stelzl, U.
Nature Methods 10 (4): 339-342. April 2013

Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells.
Feldmann, R., Fischer, C., Kodelja, V., Behrens, S., Haas, S., Vingron, M., Timmermann, B., Geikowski, A. and Sauer, S.
Nucleic Acids Research 41 (6): 3518-3531. April 2013

Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ.
de Groot, J.C., Weidner, C., Krausze, J., Kawamoto, K., Schroeder, F.C., Sauer, S. and Büssow, K.
Journal of Medicinal Chemistry 56 (4): 1535-1543. 28 February 2013

Foam cell specific LXRα ligand.
Feldmann, R., Geikowski, A., Weidner, C., Witzke, A., Kodelja, V., Schwarz, T., Gabriel, M., Erker, T. and Sauer, S.
PLOS ONE 8 (2): e57311. 25 February 2013

2012

The essence on mass spectrometry based microbial diagnostics.
Kliem, M. and Sauer, S.
Current Opinion in Microbiology 15 (3): 397-402. June 2012

Amorfrutins are potent antidiabetic dietary natural products.
Weidner, C., de Groot, J.C., Prasad, A., Freiwald, A., Quedenau, C., Kliem, M., Witzke, A., Kodelja, V., Han, C.T., Giegold, S., Baumann, M., Klebl, B., Siems, K., Müller-Kuhrt, L., Schürmann, A., Schüler, R., Pfeiffer, A.F.H., Schroeder, F.C., Büssow, K. and Sauer, S.
Proceedings of the National Academy of Sciences of the United States of America 109 (19): 7257-7262. 8 May 2012

2011

Targeted enrichment of genomic DNA regions for next-generation sequencing.
Mertes, F., Elsharawy, A., Sauer, S., van Helvoort, J.M.L.M., van der Zaag, P.J., Franke, A., Nilsson, M., Lehrach, H. and Brookes, A.J.
Briefings in Functional Genomics 10 (6): 374-386. November 2011

Differential analysis of Crohn's disease and ulcerative colitis by mass spectrometry.
Freiwald, A., Mao, L., Kodelja, V., Kliem, M., Schuldt, D., Schreiber, S., Franke, A. and Sauer, S.
Inflammatory Bowel Diseases 17 (4): 1051-1052. 1 April 2011

2010

DNA polymorphisms and haplotype patterns of transcription factors involved in barley endosperm development are associated with key agronomic traits.
Haseneyer, G., Stracke, S., Piepho, H.-P., Sauer, S., Geiger, H.H. and Graner, A.
BMC Plant Biology 10 : 5. 8 January 2010

Familiality and molecular genetics of attention networks in ADHD.
Konrad, K., Dempfle, A., Friedel, S., Heiser, P., Holtkamp, K., Walitza, S., Sauer, S., Warnke, A., Remschmidt, H., Gilsbach, S., Schäfer, H., Hinney, A., Hebebrand, J. and Herpertz-Dahlmann, B.
American Journal of Medical Genetics B 153B (1): 148-158. 5 January 2010

Mass spectrometry tools for the classification and identification of bacteria.
Sauer, S. and Kliem, M.
Nature Reviews Microbiology 8 (1): 74-82. 1 January 2010

2009

Quantification of target proteins using hydrogel antibody arrays and MALDI time-of-flight mass spectrometry (A2M2S).
Darii, E., Lebeau, D., Papin, N., Rubina, A.Y., Stomakhin, A., Tost, J., Sauer, S., Savvateeva, E., Dementieva, E., Zasedatelev, A., Makarov, A.A. and Gut, I.G.
New Biotechnology 25 (6): 404-416. 15 September 2009

Exploring the genetic link between RLS and ADHD.
Schimmelmann, B.G., Friedel, S., Nguyen, T.T., Sauer, S., Ganz Vogel, C.I., Konrad, K., Wilhelm, C., Sinzig, J., Renner, T.J., Romanos, M., Palmason, H., Dempfle, A., Walitza, S., Freitag, C., Meyer, J., Linder, M., Schäfer, H., Warnke, A., Lesch, K.P., Herpertz-Dahlmann, B., Hinney, A. and Hebebrand, J.
Journal of Psychiatric Research 43 (10): 941-945. July 2009

Phylogenetic classification and identification of bacteria by mass spectrometry.
Freiwald, A. and Sauer, S.
Nature Protocols 4 (5): 732-742. 23 April 2009

Identification of novel transcriptional regulators involved in macrophage differentiation and activation in U937 cells.
Baek, Y.-S., Haas, S., Hackstein, H., Bein, G., Hernandez-Santana, M., Lehrach, H., Sauer, S. and Seitz, H.
BMC Immunology 10 : 18. 2 April 2009

Association mapping reveals gene action and interactions in the determination of flowering time in barley.
Stracke, S., Haseneyer, G., Veyrieras, J.B., Geiger, H.H., Sauer, S., Graner, A. and Piepho, H.P.
Theoretical and Applied Genetics 118 (2): 259-273. January 2009

2008

High level of conservation between genes coding for the GAMYB transcription factor in barley (Hordeum vulgare L.) and bread wheat (Triticum aestivum L.) collections.
Haseneyer, G., Ravel, C., Dardevet, M., Balfourier, F., Sourdille, P., Charmet, G., Brunel, D., Sauer, S., Geiger, H.H., Graner, A. and Stracke, S.
Theoretical and Applied Genetics 117 (3): 321-331. August 2008

Classification and identification of bacteria by mass spectrometry and computational analysis.
Sauer, S., Freiwald, A., Maier, T., Kube, M., Reinhardt, R., Kostrzewa, M. and Geider, K.
PLOS ONE 3 (7): e2843. 30 July 2008

2007

Association and linkage of allelic variants of the dopamine transporter gene in ADHD.
Friedel, S., Saar, K., Sauer, S., Dempfle, A., Walitza, S., Renner, T., Romanos, M., Freitag, C., Seitz, C., Palmason, H., Scherag, A., Windemuth-Kieselbach, C., Schimmelmann, B.G., Wewetzer, C., Meyer, J., Warnke, A., Lesch, K.P., Reinhardt, R., Herpertz-Dahlmann, B., Linder, M., Hinney, A., Remschmidt, H., Schaefer, H., Konrad, K., Huebner, N. and Hebebrand, J.
Molecular Psychiatry 12 (10): 923-933. October 2007

The essence of DNA sample preparation for MALDI mass spectrometry.
Sauer, S.
Journal of Biochemical and Biophysical Methods 70 (2): 311-318. 10 March 2007

2006

Single-nucleotide polymorphisms: analysis by mass spectrometry.
Sauer, S., Reinhardt, R., Lehrach, H. and Gut, I.G.
Nature Protocols 1 (4): 1761-1771. 22 November 2006

Matrix-assisted laser desorption/ionization mass spectrometric analysis of DNA on microarrays.
Kepper, P., Reinhardt, R., Dahl, A., Lehrach, H. and Sauer, S.
Clinical Chemistry 52 (7): 1303-1310. July 2006

Typing of single nucleotide polymorphisms by MALDI mass spectrometry: principles and diagnostic applications.
Sauer, S.
Clinica Chimica Acta 363 (1-2): 95-105. January 2006

2005

Genome projects and the functional-genomic era.
Sauer, S., Konthur, Z. and Lehrach, H.
Combinatorial Chemistry & High Throughput Screening 8 (8): 659-667. December 2005

Miniaturization in functional genomics and proteomics.
Sauer, S., Lange, B.M.H., Gobom, J., Nyarsik, L., Seitz, H. and Lehrach, H.
Nature Reviews Genetics 6 (6): 465-764. 1 June 2005

2004

Automated solid-phase extraction for purification of single nucleotide polymorphism genotyping products prior to matrix-assisted laser desorption/ionisation time-of-flight mass spectrometric analysis.
Sauer, S., Kepper, P., Smyra, A., Dahl, A., Ferse, F.T., Lehrach, H. and Reinhardt, R.
Journal of Chromatography A 1049 (1-2): 9-16. 17 September 2004

Multiplexed hybridizations of positively charge-tagged peptide nucleic acids detected by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Bauer, O., Guerasimova, A., Sauer, S., Thamm, S., Steinfath, M., Herwig, R., Janitz, M., Lehrach, H. and Radelof, U.
Rapid Communications in Mass Spectrometry 18 (16): 1821-1829. 30 August 2004

2003

Clone-based systematic haplotyping (CSH): a procedure for physical haplotyping of whole genomes.
Burgtorf, C., Kepper, P., Hoehe, M., Schmitt, C., Reinhardt, R., Lehrach, H. and Sauer, S.
Genome Research 13 (12): 2717-2724. December 2003

Extension of the GOOD assay for genotyping single nucleotide polymorphisms by matrix-assisted laser desorption/ionization mass spectrometry.
Sauer, S. and Gut, I.G.
Rapid Communications in Mass Spectrometry 17 (12): 1265-1272. 30 June 2003

MALDI mass spectrometry analysis of single nucleotide polymorphisms by photocleavage and charge-tagging.
Sauer, S., Lehrach, H. and Reinhardt, R.
Nucleic Acids Research 31 (11): e63. 1 June 2003

2002

Genotyping single-nucleotide polymorphisms by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry.
Sauer, S. and Gut, I.G.
Journal of Chromatography B 782 (1-2): 73-87. 25 December 2002

Facile method for automated genotyping of single nucleotide polymorphisms by mass spectrometry.
Sauer, S., Gelfand, D.H., Boussicault, F., Bauer, K., Reichert, F. and Gut, I.G.
Nucleic Acids Research 30 (5): e22. 1 March 2002

2000

Full flexibility genotyping of single nucleotide polymorphisms by the GOOD assay.
Sauer, S., Lechner, D., Berlin, K., Plançon, C., Heuermann, A., Lehrach, H. and Gut, I.G.
Nucleic Acids Research 28 (23): e100. 1 December 2000

A novel procedure for efficient genotyping of single nucleotide polymorphisms.
Sauer, S., Lechner, D., Berlin, K., Lehrach, H., Escary, J.L., Fox, N. and Gut, I.G.
Nucleic Acids Research 28 (5): e13. 1 March 2000

This list was generated on Thu Oct 3 18:31:51 2024 UTC.
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