Browse by Research Team

Acta Neuropathologica Communications

Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma.
Haage, V. and Semtner, M. and Oliveira Vidal, R. and Perez Hernandez, D. and Pong, W.W. and Chen, Z. and Hambardzumyan, D. and Magrini, V. and Ly, A. and Walker, J. and Mardis, E. and Mertins, P. and Sauer, S. and Kettenmann, H. and Gutmann, D.H.
Acta Neuropathologica Communications 7 (1): 20. 14 February 2019

American Journal of Human Genetics

TTC25 deficiency results in defects of the outer dynein arm docking machinery and primary ciliary dyskinesia with left-right body asymmetry randomization.
Wallmeier, J. and Shiratori, H. and Dougherty, G.W. and Edelbusch, C. and Hjeij, R. and Loges, N.T. and Menchen, T. and Olbrich, H. and Pennekamp, P. and Raidt, J. and Werner, C. and Minegishi, K. and Shinohara, K. and Asai, Y. and Takaoka, K. and Lee, C. and Griese, M. and Memari, Y. and Durbin, R. and Kolb-Kokocinski, A. and Sauer, S. and Wallingford, J.B. and Hamada, H. and Omran, H.
American Journal of Human Genetics 99 (2): 460-469. 4 August 2016

Bi-allelic truncating mutations in TANGO2 cause infancy-onset recurrent metabolic crises with encephalocardiomyopathy.
Kremer, L.S. and Distelmaier, F. and Alhaddad, B. and Hempel, M. and Iuso, A. and Küpper, C. and Mühlhausen, C. and Kovacs-Nagy, R. and Satanovskij, R. and Graf, E. and Berutti, R. and Eckstein, G. and Durbin, R. and Sauer, S. and Hoffmann, G.F. and Strom, T.M. and Santer, R. and Meitinger, T. and Klopstock, T. and Prokisch, H. and Haack, T.B.
American Journal of Human Genetics 98 (2): 358-362. 4 February 2016

American Journal of Medical Genetics B

Familiality and molecular genetics of attention networks in ADHD.
Konrad, K. and Dempfle, A. and Friedel, S. and Heiser, P. and Holtkamp, K. and Walitza, S. and Sauer, S. and Warnke, A. and Remschmidt, H. and Gilsbach, S. and Schäfer, H. and Hinney, A. and Hebebrand, J. and Herpertz-Dahlmann, B.
American Journal of Medical Genetics B 153B (1): 148-158. 5 January 2010

American Journal of Respiratory Cell and Molecular Biology

Immunofluorescence analysis and diagnosis of primary ciliary dyskinesia with radial spoke defects.
Frommer, A. and Hjeij, R. and Loges, N.T. and Edelbusch, C. and Jahnke, C. and Raidt, J. and Werner, C. and Wallmeier, J. and Große-Onnebrink, J. and Olbrich, H. and Cindrić, S. and Jaspers, M. and Boon, M. and Memari, Y. and Durbin, R. and Kolb-Kokocinski, A. and Sauer, S. and Marthin, J.K. and Nielsen, K.G. and Amirav, I. and Elias, N. and Kerem, E. and Shoseyov, D. and Haeffner, K. and Omran, H.
American Journal of Respiratory Cell and Molecular Biology 53 (4): 563-573. 1 October 2015

Angewandte Chemie International Edition

Discovery and characterization of protein-modifying natural products by MALDI mass spectrometry reveal potent SIRT1 and p300 inhibitors.
Holzhauser, S. and Freiwald, A. and Weise, C. and Multhaup, G. and Han, C.T. and Sauer, S.
Angewandte Chemie International Edition 52 (19): 5171-5174. 3 May 2013

Annals of Clinical and Translational Neurology

Deficiency of ECHS1 causes mitochondrial encephalopathy with cardiac involvement.
Haack, T.B. and Jackson, C.B. and Murayama, K. and Kremer, L.S. and Schaller, A. and Kotzaeridou, U. and de Vries, M.C. and Schottmann, G. and Santra, S. and Büchner, B. and Wieland, T. and Graf, E. and Freisinger, P. and Eggimann, S. and Ohtake, A. and Okazaki, Y. and Kohda, M. and Kishita, Y. and Tokuzawa, Y. and Sauer, S. and Memari, Y. and Kolb-Kokocinski, A. and Durbin, R. and Hasselmann, O. and Cremer, K. and Albrecht, B. and Wieczorek, D. and Engels, H. and Hahn, D. and Zink, A.M. and Alston, C.L. and Taylor, R.W. and Rodenburg, R.J. and Trollmann, R. and Sperl, W. and Strom, T.M. and Hoffmann, G.F. and Mayr, J.A. and Meitinger, T. and Bolognini, R. and Schuelke, M. and Nuoffer, J.M. and Kölker, S. and Prokisch, H. and Klopstock, T.
Annals of Clinical and Translational Neurology 2 (5): 492-509. May 2015

Applied Microbiology and Biotechnology

Health-beneficial nutraceuticals - myth or reality?
Sauer, S. and Plauth, A.
Applied Microbiology and Biotechnology 101 (3): 951-961. February 2017

BMC Genomics

Relationship between genome and epigenome - challenges and requirements for future research.
Almouzni, G. and Altucci, L. and Amati, B. and Ashley, N. and Baulcombe, D. and Beaujean, N. and Bock, C. and Bongcam-Rudloff, E. and Bousquet, J. and Braun, S. and Bressac-de Paillerets, B. and Bussemakers, M. and Clarke, L. and Conesa, A. and Estivill, X. and Fazeli, A. and Grgurević, N. and Gut, I. and Heijmans, B.T. and Hermouet, S. and Houwing-Duistermaat, J. and Iacobucci, I. and Ilaš, J. and Kandimalla, R. and Krauss-Etschmann, S. and Lasko, P. and Lehmann, S. and Lindroth, A. and Majdič, G. and Marcotte, E. and Martinelli, G. and Martinet, N. and Meyer, E. and Miceli, C. and Mills, K. and Moreno-Villanueva, M. and Morvan, G. and Nickel, D. and Niesler, B. and Nowacki, M. and Nowak, J. and Ossowski, S. and Pelizzola, M. and Pochet, R. and Potočnik, U. and Radwanska, M. and Raes, J. and Rattray, M. and Robinson, M.D. and Roelen, B. and Sauer, S. and Schinzer, D. and Slagboom, E. and Spector, T. and Stunnenberg, H.G. and Tiligada, E. and Torres-Padilla, M.E. and Tsonaka, R. and Van Soom, A. and Vidaković, M. and Widschwendter, M.
BMC Genomics 15 : 487. 18 June 2014

BMC Immunology

Identification of novel transcriptional regulators involved in macrophage differentiation and activation in U937 cells.
Baek, Y.-S. and Haas, S. and Hackstein, H. and Bein, G. and Hernandez-Santana, M. and Lehrach, H. and Sauer, S. and Seitz, H.
BMC Immunology 10 : 18. 2 April 2009

BMC Plant Biology

DNA polymorphisms and haplotype patterns of transcription factors involved in barley endosperm development are associated with key agronomic traits.
Haseneyer, G. and Stracke, S. and Piepho, H.-P. and Sauer, S. and Geiger, H.H. and Graner, A.
BMC Plant Biology 10 : 5. 8 January 2010

Basic Research in Cardiology

CRISPLD1: a novel conserved target in the transition to human heart failure.
Khadjeh, S. and Hindmarsh, V. and Weber, F. and Cyganek, L. and Vidal, R.O. and Torkieh, S. and Streckfuss-Bömeke, K. and Lbik, D. and Tiburcy, M. and Mohamed, B.A. and Bonn, S. and Toischer, K. and Hasenfuss, G.
Basic Research in Cardiology 115 (3): 27. 7 March 2020

Bioinformatics

PHOXTRACK-a tool for interpreting comprehensive datasets of post-translational modifications of proteins.
Weidner, C. and Fischer, C. and Sauer, S.
Bioinformatics 30 (23): 3410-3411. 1 December 2014

Biomedicines

Generation of hiPSC-derived skeletal muscle cells: exploiting the potential of skeletal muscle-derived hiPSCs.
Metzler, E. and Escobar, H. and Sunaga-Franze, D.Y. and Sauer, S. and Diecke, S. and Spuler, S.
Biomedicines 10 (5): 1204. 23 May 2022

Brain

Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Smajić, S. and Prada-Medina, C.A. and Landoulsi, Z. and Ghelfi, J. and Delcambre, S. and Dietrich, C. and Jarazo, J. and Henck, J. and Balachandran, S. and Pachchek, S. and Morris, C.M. and Antony, P. and Timmermann, B. and Sauer, S. and Pereira, S.L. and Schwamborn, J.C. and May, P. and Grünewald, A. and Spielmann, M.
Brain 145 (3): 964-978. March 2022

Breast Cancer Research and Treatment

Clonality of circulating tumor cells in breast cancer brain metastasis patients.
Riebensahm, C. and Joosse, S.A. and Mohme, M. and Hanssen, A. and Matschke, J. and Goy, Y. and Witzel, I. and Lamszus, K. and Kropidlowski, J. and Petersen, C. and Kolb-Kokocinski, A. and Sauer, S. and Borgmann, K. and Glatzel, M. and Müller, V. and Westphal, M. and Riethdorf, S. and Pantel, K. and Wikman, H.
Breast Cancer Research and Treatment 21 (1): 101. 3 September 2019

Briefings in Functional Genomics

Targeted enrichment of genomic DNA regions for next-generation sequencing.
Mertes, F. and Elsharawy, A. and Sauer, S. and van Helvoort, J.M.L.M. and van der Zaag, P.J. and Franke, A. and Nilsson, M. and Lehrach, H. and Brookes, A.J.
Briefings in Functional Genomics 10 (6): 374-386. November 2011

Cancer Immunology Immunotherapy

Prostaglandin E(2) in a TLR3- and 7/8-agonist-based DC maturation cocktail generates mature, cytokine-producing, migratory DCs but impairs antigen cross-presentation to CD8(+) T cells.
Gierlich, P. and Lex, V. and Technau, A. and Keupp, A. and Morper, L. and Glunz, A. and Sennholz, H. and Rachor, J. and Sauer, S. and Marcu, A. and Grigoleit, G.U. and Wölfl, M. and Schlegel, P.G. and Eyrich, M.
Cancer Immunology Immunotherapy 69 (6): 1029-1042. June 2020

Cell

The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery.
Stunnenberg, H.G. and Hirst, M.
Cell 167 (7): 1145-1149. 17 November 2016

Cell Reports

The Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer.
Zhu, Q. and Fang, L. and Heuberger, J. and Kranz, A. and Schipper, J. and Scheckenbach, K. and Oliveira Vidal, R. and Sunaga-Franze, D.Y. and Müller, M. and Wulf-Goldenberg, A. and Sauer, S. and Birchmeier, W.
Cell Reports 26 (2): 415-428. 8 January 2019

Transient N-6-methyladenosine transcriptome sequencing reveals a regulatory role of m6A in splicing efficiency.
Louloupi, A. and Ntini, E. and Conrad, T. and Ørom, U.A.V.
Cell Reports 23 (12): 3429-3437. 19 June 2018

Cell Stem Cell

Resolving fates and single-cell transcriptomes of hematopoietic stem cell clones by PolyloxExpress barcoding.
Pei, W. and Shang, F. and Wang, X. and Fanti, A.K. and Greco, A. and Busch, K. and Klapproth, K. and Zhang, Q. and Quedenau, C. and Sauer, S. and Feyerabend, T.B. and Höfer, T. and Rodewald, H.R.
Cell Stem Cell 27 (3): 383-395. 3 September 2020

Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M. and Fischer, C. and Urzi, A. and Vidal, R. and Kunz, S. and Ruffault, P.L. and Kabuss, L. and Hube, I. and Gazzerro, E. and Birchmeier, C. and Spuler, S. and Sauer, S. and Gouti, M.
Cell Stem Cell 26 (2): 172-186. 6 February 2020

ChemBioChem

Amorfrutins: a promising class of natural products that are beneficial to health.
Sauer, S.
ChemBioChem 15 (9): 1231-1238. 16 June 2014

Clinica Chimica Acta

Typing of single nucleotide polymorphisms by MALDI mass spectrometry: principles and diagnostic applications.
Sauer, S.
Clinica Chimica Acta 363 (1-2): 95-105. January 2006

Clinical Chemistry

Matrix-assisted laser desorption/ionization mass spectrometric analysis of DNA on microarrays.
Kepper, P. and Reinhardt, R. and Dahl, A. and Lehrach, H. and Sauer, S.
Clinical Chemistry 52 (7): 1303-1310. July 2006

Combinatorial Chemistry & High Throughput Screening

Genome projects and the functional-genomic era.
Sauer, S. and Konthur, Z. and Lehrach, H.
Combinatorial Chemistry & High Throughput Screening 8 (8): 659-667. December 2005

Communications Biology

Maximizing transcription of nucleic acids with efficient T7 promoters.
Conrad, T. and Plumbom, I. and Alcobendas, M. and Vidal, R. and Sauer, S.
Communications Biology 3 (1): 439. 14 August 2020

Current Opinion in Microbiology

The essence on mass spectrometry based microbial diagnostics.
Kliem, M. and Sauer, S.
Current Opinion in Microbiology 15 (3): 397-402. June 2012

Data in Brief

Data of oxygen- and pH-dependent oxidation of resveratrol.
Plauth, A. and Geikowski, A. and Cichon, S. and Wowro, S.J. and Liedgens, L. and Rousseau, M. and Weidner, C. and Fuhr, L. and Kliem, M. and Jenkins, G. and Lotito, S. and Wainwright, L.J. and Sauer, S.
Data in Brief 9 : 433-437. December 2016

Development

GAS1 is required for Notch-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.
Marczenke, M. and Sunaga, D. and Popp, O. and Althaus, I.W. and Sauer, S. and Mertins, P. and Christ, A. and Allen, B.L. and Willnow, T.E.
Development 148 (21): dev200080. 11 November 2021

Diabetologia

Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPARγ) agonist with potent glucose-lowering properties.
Weidner, C. and Wowro, S.J. and Freiwald, A. and Kawamoto, K. and Witzke, A. and Kliem, M. and Siems, K. and Müller-Kuhrt, L. and Schroeder, F.C. and Sauer, S.
Diabetologia 56 (8): 1802-1812. August 2013

European Journal of Human Genetics

A novel splicing mutation in the IQSEC2 gene that modulates the phenotype severity in a family with intellectual disability.
Madrigal, I. and Alvarez-Mora, M.I. and Rosell, J. and Rodríguez-Revenga, L. and Karlberg, O. and Sauer, S. and Syvänen, A.C. and Mila, M.
European Journal of Human Genetics 24 (8): 1117-1123. August 2016

European Journal of Immunology

Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined.
Kaleviste, E. and Saare, M. and Leahy, T.R. and Bondet, V. and Duffy, D. and Mogensen, T. and Jørgensen, S.E. and Nurm, H. and Ip, W. and Davies, E.G. and Sauer, S. and Syvänen, A.C. and Milani, L. and Peterson, P. and Kisand, K.
European Journal of Immunology 49 (5): 790-800. May 2019

Expert Review of Proteomics

Protein set analyses: how could this impact the clinic?
Sauer, S.
Expert Review of Proteomics 10 (4): 305-307. August 2013

Forests

Transcriptome analysis reveals putative genes involved in the lipid metabolism of chaulmoogra oil biosynthesis in Carpotroche brasiliensis (Raddi) A.Gray, a tropical tree species.
Vasconcelos, L.M. and Bittencourt, F. and Vidal, R.O. and Silva, E.M.A. and Costa, E.A. and Micheli, F. and Kirst, M. and Pirovani, C.P. and Gaiotto, F.A
Forests 13 (11): 1806. 29 October 2022

Free Radical Biology and Medicine

Hormetic shifting of redox environment by pro-oxidative resveratrol protects cells against stress.
Plauth, A. and Geikowski, A. and Cichon, S. and Wowro, S.J. and Liedgens, L. and Rousseau, M. and Weidner, C. and Fuhr, L. and Kliem, M. and Jenkins, G. and Lotito, S. and Wainwright, L.J. and Sauer, S.
Free Radical Biology and Medicine 99 : 608-622. October 2016

Frontiers in Genetics

Dissecting the effect of genetic variation on the hepatic expression of drug disposition genes across the collaborative cross mouse strains.
Nachshon, A. and Abu-Toamih Atamni, H.J. and Steuerman, Y. and Sheikh-Hamed, R. and Dorman, A. and Mott, R. and Dohm, J.C. and Lehrach, H. and Sultan, M. and Shamir, R. and Sauer, S. and Himmelbauer, H. and Iraqi, F.A. and Gat-Viks, I.
Frontiers in Genetics 7 : 172. 5 October 2016

Frontiers in Immunology

Comparative analysis of the secretome and interactome of Trypanosoma cruzi and Trypanosoma rangeli reveals species specific immune response modulating proteins.
Watanabe Costa, R. and Batista, M.F. and Meneghelli, I. and Vidal, R.O. and Nájera, C.A. and Mendes, A.C. and Andrade-Lima, I.A. and da Silveira, J.F. and Lopes, L.R. and Ferreira, L.R.P. and Antoneli, F. and Bahia, D.
Frontiers in Immunology 11 : 1774. 27 August 2020

Genes & Development

The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization.
Daniel, B. and Czimmerer, Z. and Halasz, L. and Boto, P. and Kolostyak, Z. and Poliska, S. and Berger, W.K. and Tzerpos, P. and Nagy, G. and Horvath, A. and Hajas, G. and Cseh, T. and Nagy, A. and Sauer, S. and Francois-Deleuze, J. and Szatmari, I. and Bacsi, A. and Nagy, L.
Genes & Development 34 (21-22): 1474-1492. 1 November 2020

Genome Biology

Splicing-accessible coding 3'UTRs control protein stability and interaction networks.
Preussner, M. and Gao, Q. and Morrison, E. and Herdt, O. and Finkernagel, F. and Schumann, M. and Krause, E. and Freund, C. and Chen, W. and Heyd, F.
Genome Biology 21 (1): 186. 29 July 2020

Genome Research

Clone-based systematic haplotyping (CSH): a procedure for physical haplotyping of whole genomes.
Burgtorf, C. and Kepper, P. and Hoehe, M. and Schmitt, C. and Reinhardt, R. and Lehrach, H. and Sauer, S.
Genome Research 13 (12): 2717-2724. December 2003

Gut

Faecal microbiota composition associates with abdominal pain in the general population.
Hadizadeh, F. and Bonfiglio, F. and Belheouane, M. and Vallier, M. and Sauer, S. and Bang, C. and Bujanda, L. and Andreasson, A. and Agreus, L. and Engstrand, L. and Talley, N.J. and Rafter, J. and Baines, J.F. and Walter, S. and Franke, A. and D'Amato, M.
Gut 67 (4): 778-779. 8 March 2018

Human Brain Mapping

Regional gene expression patterns are associated with task-specific brain activation during reward and emotion processing measured with functional MRI.
Komorowski, A. and Murgaš, M. and Vidal, R. and Singh, A. and Gryglewski, G. and Kasper, S. and Wiltfang, J. and Lanzenberger, R. and Goya-Maldonado, R.
Human Brain Mapping 43 (17): 5266-5280. 1 December 2022

Human Molecular Genetics

De novo mutations implicate novel genes in systemic lupus erythematosus.
Pullabhatla, V. and Roberts, A.L. and Lewis, M.J. and Mauro, D. and Morris, D.L. and Odhams, C.A. and Tombleson, P. and Liljedahl, U. and Vyse, S. and Simpson, M.A. and Sauer, S. and de Rinaldis, E. and Syvänen, A.C. and Vyse, T.J.
Human Molecular Genetics 27 (3): 421-429. 1 February 2018

Homozygous loss-of-function variants in european cosmopolitan and isolate populations.
Kaiser, V.B. and Svinti, V. and Prendergast, J.G. and Chau, Y.Y. and Campbell, A. and Patarcic, I. and Barroso, I. and Joshi, P.K. and Hastie, N.D. and Miljkovic, A. and Taylor, M.S. and Enroth, S. and Memari, Y. and Kolb-Kokocinski, A. and Wright, A.F. and Gyllensten, U. and Durbin, R. and Rudan, I. and Campbell, H. and Polašek, O. and Johansson, A. and Sauer, S. and Porteous, D.J. and Fraser, R.M. and Drake, C. and Vitart, V. and Hayward, C. and Semple, C.A. and Wilson, J.F.
Human Molecular Genetics 24 (19): 5464-5474. 1 October 2015

Hypertension

Maternal angiotensin increases placental leptin in early gestation via an alternative renin-angiotensin system pathway: suggesting a link to preeclampsia.
Nonn, O. and Fischer, C. and Geisberger, S. and El-Heliebi, A. and Kroneis, T. and Forstner, D. and Desoye, G. and Staff, A.C. and Sugulle, M. and Dechend, R. and Pecks, U. and Kollmann, M. and Stern, C. and Cartwright, J.E. and Whitley, G.S. and Thilaganathan, B. and Wadsack, C. and Huppertz, B. and Herse, F. and Gauster, M.
Hypertension 77 (5): 1723-1736. May 2021

Immunity

A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation.
Vallecillo-García, P. and Orgeur, M. and Comai, G. and Poehle-Kronnawitter, S. and Fischer, C. and Gloger, M. and Dumas, C.E. and Giesecke-Thiel, C. and Sauer, S. and Tajbakhsh, S. and Höpken, U.E. and Stricker, S.
Immunity 56 (6): 1204-1219. 13 June 2023

The nuclear receptor PPARγ controls progressive macrophage polarization as a ligand-insensitive epigenomic ratchet of transcriptional memory.
Daniel, B. and Nagy, G. and Czimmerer, Z. and Horvath, A. and Hammers, D.W. and Cuaranta-Monroy, I. and Poliska, S. and Tzerpos, P. and Kolostyak, Z. and Hays, T.T. and Patsalos, A. and Houtman, R. and Sauer, S. and Francois-Deleuze, J. and Rastinejad, F. and Balint, B.L. and Sweeney, H.L. and Nagy, L.
Immunity 49 (4): 615-626. 16 October 2018

The transcription factor STAT6 mediates direct repression of inflammatory enhancers and limits activation of alternatively polarized macrophages.
Czimmerer, Z. and Daniel, B. and Horvath, A. and Rückerl, D. and Nagy, G. and Kiss, M. and Peloquin, M. and Budai, M.M. and Cuaranta-Monroy, I. and Simandi, Z. and Steiner, L. and Nagy, B. and Poliska, S. and Banko, C. and Bacso, Z. and Schulman, I.G. and Sauer, S. and Deleuze, J.F. and Allen, J.E. and Benko, S. and Nagy, L.
Immunity 48 (1): 75-90. 16 January 2018

Inflammatory Bowel Diseases

Differential analysis of Crohn's disease and ulcerative colitis by mass spectrometry.
Freiwald, A. and Mao, L. and Kodelja, V. and Kliem, M. and Schuldt, D. and Schreiber, S. and Franke, A. and Sauer, S.
Inflammatory Bowel Diseases 17 (4): 1051-1052. 1 April 2011

International Journal of Molecular Sciences

The transcription factor EB (TFEB) sensitizes the heart to chronic pressure overload.
Wundersitz, S. and Pablo Tortola, C. and Schmidt, S. and Oliveira Vidal, R. and Kny, M. and Hahn, A. and Zanders, L. and Katus, H.A. and Sauer, S. and Butter, C. and Luft, F.C. and Müller, O.J. and Fielitz, J.
International Journal of Molecular Sciences 23 (11): 5943. 25 May 2022

JCI Insight

EBAG9 controls CD8(+) T cell memory formation responding to tumor challenge in mice.
Rehm, A. and Wirges, A. and Hoser, D. and Fischer, C. and Herda, S. and Gerlach, K. and Sauer, S. and Willimsky, G. and Hoepken, U.E.
JCI Insight 7 (11): e155534. 8 June 2022

Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart.
Vidal, R. and Wagner, J.U.G. and Braeuning, C. and Fischer, C. and Patrick, R. and Tombor, L. and Muhly-Reinholz, M. and John, D. and Kliem, M. and Conrad, T. and Guimarães-Camboa, N. and Harvey, R. and Dimmeler, S. and Sauer, S.
JCI Insight 4 (22): e131092. 14 November 2019

Journal of Autoimmunity

Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease patients reveals changes in genes associated with T cell receptor signaling.
Limbach, M. and Saare, M. and Tserel, L. and Kisand, K. and Eglit, T. and Sauer, S. and Axelsson, T. and Syvänen, A.C. and Metspalu, A. and Milani, L. and Peterson, P.
Journal of Autoimmunity 67 : 46-56. February 2016

Journal of Biochemical and Biophysical Methods

The essence of DNA sample preparation for MALDI mass spectrometry.
Sauer, S.
Journal of Biochemical and Biophysical Methods 70 (2): 311-318. 10 March 2007

Journal of Chromatography A

Automated solid-phase extraction for purification of single nucleotide polymorphism genotyping products prior to matrix-assisted laser desorption/ionisation time-of-flight mass spectrometric analysis.
Sauer, S. and Kepper, P. and Smyra, A. and Dahl, A. and Ferse, F.T. and Lehrach, H. and Reinhardt, R.
Journal of Chromatography A 1049 (1-2): 9-16. 17 September 2004

Journal of Chromatography B

Genotyping single-nucleotide polymorphisms by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry.
Sauer, S. and Gut, I.G.
Journal of Chromatography B 782 (1-2): 73-87. 25 December 2002

Journal of Clinical Endocrinology & Metabolism

RNA-sequencing and somatic mutation status of adrenocortical tumors: novel pathogenetic insights.
Di Dalmazi, G. and Altieri, B. and Scholz, C. and Sbiera, S. and Luconi, M. and Waldman, J. and Kastelan, D. and Ceccato, F. and Chiodini, I. and Arnaldi, G. and Riester, A. and Osswald, A. and Beuschlein, F. and Sauer, S. and Fassnacht, M. and Appenzeller, S. and Ronchi, C.L.
Journal of Clinical Endocrinology & Metabolism 105 (12): dgaa616. December 2020

Journal of Clinical Pathology

Efficient application of next-generation sequencing for the diagnosis of rare genetic syndromes.
Madrigal, I. and Alvarez-Mora, M.I. and Karlberg, O. and Rodríguez-Revenga, L. and Elurbe, D.M. and Rabionet, R. and Mur, A. and Pie, J. and Ballesta, F. and Sauer, S. and Syvänen, A.C. and Milà, M.
Journal of Clinical Pathology 67 (12): 1099-1103. December 2014

Journal of Immunology Research

RNA-seq based transcriptome analysis of the type I interferon host response upon vaccinia virus infection of mouse cells.
Hernáez, B. and Alonso, G. and Alonso-Lobo, J.M. and Rastrojo, A. and Fischer, C. and Sauer, S. and Aguado, B. and Alcamí, A.
Journal of Immunology Research 2017 : 5157626. 9 February 2017

Journal of Investigative Dermatology

GORAB missense mutations disrupt RAB6 and ARF5 binding and golgi targeting.
Egerer, J. and Emmerich, D. and Fischer-Zirnsak, B. and Chan, W.L. and Meierhofer, D. and Tuysuz, B. and Marschner, K. and Sauer, S. and Barr, F.A. and Mundlos, S. and Kornak, U.
Journal of Investigative Dermatology 135 (10): 2368-2376. October 2015

Journal of Medical Genetics

Identification of novel genetic causes of Rett syndrome-like phenotypes.
Lopes, F. and Barbosa, M. and Ameur, A. and Soares, G. and de Sá, J. and Dias, A.I. and Oliveira, G. and Cabral, P. and Temudo, T. and Calado, E. and Cruz, I.F. and Vieira, J.P. and Oliveira, R. and Esteves, S. and Sauer, S. and Jonasson, I. and Syvänen, A.C. and Gyllensten, U. and Pinto, D. and Maciel, P.
Journal of Medical Genetics 53 (3): 190-199. March 2016

Journal of Medicinal Chemistry

Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ.
de Groot, J.C. and Weidner, C. and Krausze, J. and Kawamoto, K. and Schroeder, F.C. and Sauer, S. and Büssow, K.
Journal of Medicinal Chemistry 56 (4): 1535-1543. 28 February 2013

Journal of Natural Products

Amorfrutin C induces apoptosis and inhibits proliferation in colon cancer cells through targeting mitochondria.
Weidner, C. and Rousseau, M. and Micikas, R.J. and Fischer, C. and Plauth, A. and Wowro, S.J. and Siems, K. and Hetterling, G. and Kliem, M. and Schroeder, F.C. and Sauer, S.
Journal of Natural Products 79 (1): 2-12. 22 January 2016

Amorfrutins are natural PPARγ agonists with potent anti-inflammatory properties.
Fuhr, L. and Rousseau, M. and Plauth, A. and Schroeder, F.C. and Sauer, S.
Journal of Natural Products 78 (5): 1160-1164. 22 May 2015

Journal of Proteome Research

Efficient application of de novo RNA assemblers for proteomics informed by transcriptomics.
Luge, T. and Fischer, C. and Sauer, S.
Journal of Proteome Research 15 (10): 3938-3943. 7 October 2016

Integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs.
Meierhofer, D. and Weidner, C. and Sauer, S.
Journal of Proteome Research 13 (12): 5592-5602. 5 December 2014

Journal of Psychiatric Research

Exploring the genetic link between RLS and ADHD.
Schimmelmann, B.G. and Friedel, S. and Nguyen, T.T. and Sauer, S. and Ganz Vogel, C.I. and Konrad, K. and Wilhelm, C. and Sinzig, J. and Renner, T.J. and Romanos, M. and Palmason, H. and Dempfle, A. and Walitza, S. and Freitag, C. and Meyer, J. and Linder, M. and Schäfer, H. and Warnke, A. and Lesch, K.P. and Herpertz-Dahlmann, B. and Hinney, A. and Hebebrand, J.
Journal of Psychiatric Research 43 (10): 941-945. July 2009

Journal of Virology

Dissecting herpes simplex virus 1-induced host shutoff at the RNA level.
Friedel, C.C. and Whisnant, A.W. and Djakovic, L. and Rutkowski, A.J. and Friedl, M.S. and Kluge, M. and Williamson, J.C. and Sai, S. and Vidal, R.O. and Sauer, S. and Hennig, T. and Grothey, A. and Milić, A. and Prusty, B.K. and Lehner, P.J. and Matheson, N.J. and Erhard, F. and Dölken, L.
Journal of Virology 95 (3): e01399-20. 13 January 2021

Life Science Alliance

Mammalian splicing divergence is shaped by drift, buffering in trans, and a scaling law.
Zou, X. and Schaefke, B. and Li, Y. and Jia, F. and Sun, W. and Li, G. and Liang, W. and Reif, T. and Heyd, F. and Gao, Q. and Tian, S. and Li, Y. and Tang, Y. and Fang, L. and Hu, Y. and Chen, W.
Life Science Alliance 5 (4): e202101333. April 2022

Methods in Molecular Biology

Generating sample-specific databases for mass spectrometry-based proteomic analysis by using RNA sequencing.
Luge, T. and Sauer, S.
Methods in Molecular Biology 1394 : 219-232. 2016

Molecular & Cellular Proteomics

Protein sets define disease states and predict in vivo effects of drug treatment.
Meierhofer, D. and Weidner, C. and Hartmann, L. and Mayr, J.A. and Han, C.T. and Schroeder, F.C. and Sauer, S.
Molecular & Cellular Proteomics 12 (7): 1965-1979. 1 July 2013

Molecular Cell

OCT4 acts as an integrator of pluripotency and signal-induced differentiation.
Simandi, Z. and Horvath, A. and Wright, L.C. and Cuaranta-Monroy, I. and De Luca, I. and Karolyi, K. and Sauer, S. and Deleuze, J.F. and Gudas, L.J. and Cowley, S.M. and Nagy, L.
Molecular Cell 63 (4): 647-661. 18 August 2016

Molecular Genetics & Genomic Medicine

HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M. and Yu, Y. and Liang, L. and Vuralli, D. and Froehler, S. and Kuehnen, P. and Du Bois, P. and Zhang, J. and Cao, A. and Liu, Y. and Hussain, K. and Fielitz, J. and Jia, S. and Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7 (5): e602. May 2019

Molecular Metabolism

Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism.
Correia, J.C. and Massart, J. and de Boer, J.F. and Porsmyr-Palmertz, M. and Martínez-Redondo, V. and Agudelo, L.Z. and Sinha, I. and Meierhofer, D. and Ribeiro, V. and Björnholm, M. and Sauer, S. and Dahlman-Wright, K. and Zierath, J.R. and Groen, A.K. and Ruas, J.L.
Molecular Metabolism 4 (12): 891-902. December 2015

Molecular Nutrition & Food Research

Lemon balm extract causes potent antihyperglycemic and antihyperlipidemic effects in insulin-resistant obese mice.
Weidner, C. and Wowro, S.J. and Freiwald, A. and Kodelja, V. and Abdel-Aziz, H. and Kelber, O. and Sauer, S.
Molecular Nutrition & Food Research 58 (4): 903-907. April 2014

Molecular Psychiatry

Transcriptome of iPSC-derived neuronal cells reveals a module of co-expressed genes consistently associated with autism spectrum disorder.
Griesi-Oliveira, K. and Fogo, M.S. and Pinto, B.G.G. and Alves, A.Y. and Suzuki, A.M. and Morales, A.G. and Ezquina, S. and Sosa, O.J. and Sutton, G.J. and Sunaga-Franze, D.Y. and Bueno, A.P. and Seabra, G. and Sardinha, L. and Costa, S.S. and Rosenberg, C. and Zachi, E.C. and Sertie, A.L. and Martins-de-Souza, D. and Reis, E.M. and Voineagu, I. and Passos-Bueno, M.R.
Molecular Psychiatry 26 (5): 1589-1605. May 2021

Association and linkage of allelic variants of the dopamine transporter gene in ADHD.
Friedel, S. and Saar, K. and Sauer, S. and Dempfle, A. and Walitza, S. and Renner, T. and Romanos, M. and Freitag, C. and Seitz, C. and Palmason, H. and Scherag, A. and Windemuth-Kieselbach, C. and Schimmelmann, B.G. and Wewetzer, C. and Meyer, J. and Warnke, A. and Lesch, K.P. and Reinhardt, R. and Herpertz-Dahlmann, B. and Linder, M. and Hinney, A. and Remschmidt, H. and Schaefer, H. and Konrad, K. and Huebner, N. and Hebebrand, J.
Molecular Psychiatry 12 (10): 923-933. October 2007

Molecular Systems Biology

Nonproductive exposure of PBMCs to SARS‐CoV ‐2 induces cell‐intrinsic innate immune responses.
Kazmierski, J. and Friedmann, K. and Postmus, D. and Emanuel, J. and Fischer, C. and Jansen, J. and Richter, A. and Bosquillon de Jarcy, L. and Schüler, C. and Sohn, M. and Sauer, S. and Drosten, C. and Saliba, A.E. and Sander, L.E. and Müller, M.A. and Niemeyer, D. and Goffinet, C.
Molecular Systems Biology 18 (8): e10961. 1 August 2022

Molecular and Cellular Biology

Loss of the hematopoietic stem cell factor GATA2 in the osteogenic lineage impairs trabecularization and mechanical strength of bone.
Tolkachov, A. and Fischer, C. and Ambrosi, T.H. and Bothe, M. and Han, C.T. and Muenzner, M. and Mathia, S. and Salminen, M. and Seifert, G. and Thiele, M. and Duda, G.N. and Meijsing, S.H. and Sauer, S. and Schulz, T.J. and Schupp, M.
Molecular and Cellular Biology 38 (12): e00599-17. June 2018

Molecular and Cellular Endocrinology

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages.
Czimmerer, Z. and Nagy, Z.S. and Nagy, G. and Horvath, A. and Silye-Cseh, T. and Kriston, A. and Jonas, D. and Sauer, S. and Steiner, L. and Daniel, B. and Deleuze, J.F. and Nagy, L.
Molecular and Cellular Endocrinology 471 : 63-74. 15 August 2018

RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification.
Simandi, Z. and Horvath, A. and Cuaranta-Monroy, I. and Sauer, S. and Deleuze, J.F. and Nagy, L.
Molecular and Cellular Endocrinology 471 : 51-62. 15 August 2018

Nature

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.
Pei, W. and Feyerabend, T.B. and Rössler, J. and Wang, X. and Postrach, D. and Busch, K. and Rode, I. and Klapproth, K. and Dietlein, N. and Quedenau, C. and Chen, W. and Sauer, S. and Wolf, S. and Höfer, T. and Rodewald, H.Re.
Nature 548 (7668): 456-460. 24 August 2017

Nature Biotechnology

Benchmarking single-cell RNA-sequencing protocols for cell atlas projects.
Mereu, E. and Lafzi, A. and Moutinho, C. and Ziegenhain, C. and McCarthy, D.J. and Álvarez-Varela, A. and Batlle, E. and Sagar, and Grün, D. and Lau, J.K. and Boutet, S.C. and Sanada, C. and Ooi, A. and Jones, R.C. and Kaihara, K. and Brampton, C. and Talaga, Y. and Sasagawa, Y. and Tanaka, K. and Hayashi, T. and Braeuning, C. and Fischer, C. and Sauer, S. and Trefzer, T. and Conrad, C. and Adiconis, X. and Nguyen, L.T. and Regev, A. and Levin, J.Z. and Parekh, S. and Janjic, A. and Wange, L.E. and Bagnoli, J.W. and Enard, W. and Gut, M. and Sandberg, R. and Nikaido, I. and Gut, I. and Stegle, O. and Heyn, H.
Nature Biotechnology 38 (6): 747-755. June 2020

Nature Cell Biology

R-spondin-3 induces secretory, antimicrobial Lgr5(+) cells in the stomach.
Sigal, M. and Del Mar Reinés, M. and Müllerke, S. and Fischer, C. and Kapalczynska, M. and Berger, H. and Bakker, E.R.M. and Mollenkopf, H.J. and Rothenberg, M.E. and Wiedenmann, B. and Sauer, S. and Meyer, T.F.
Nature Cell Biology 21 (7): 812-823. July 2019

Nature Communications

BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.
Kapalczynska, M. and Lin, M. and Maertzdorf, J. and Heuberger, J. and Muellerke, S. and Zuo, X. and Vidal, R. and Shureiqi, I. and Fischer, A.S. and Sauer, S. and Berger, H. and Kidess, E. and Mollenkopf, H.J. and Tacke, F. and Meyer, T.F. and Sigal, M.
Nature Communications 13 (1): 1577. 24 March 2022

The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Grinat, J. and Heuberger, J. and Vidal, R. and Goveas, N. and Kosel, F. and Berenguer-Llergo, A. and Kranz, A. and Wulf-Goldenberg, A. and Behrens, D. and Melcher, B. and Sauer, S. and Vieth, M. and Batlle, E. and Stewart, A. and Birchmeier, W.
Nature Communications 11 (1): 6422. 21 December 2020

The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models.
Klems, A. and van Rijssel, J. and Ramms, A.S. and Wild, R. and Hammer, J. and Merkel, M. and Derenbach, L. and Préau, L. and Hinkel, R. and Suarez-Martinez, I. and Schulte-Merker, S. and Vidal, R. and Sauer, S. and Kivelä, R. and Alitalo, K. and Kupatt, C. and van Buul, J.D. and le Noble, F.
Nature Communications 11 (1): 5319. 21 October 2020

Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.
Marg, A. and Escobar Fernandez, H. and Karaiskos, N. and Grunwald, S.A. and Metzler, E. and Kieshauer, J. and Sauer, S. and Pasemann, D. and Malfatti, E. and Mompoint, D. and Quijano-Roy, S. and Boltengagen, A. and Schneider, J. and Schülke, M. and Kunz, S. and Carlier, R. and Birchmeier, C. and Amthor, H. and Spuler, A. and Kocks, C. and Rajewsky, N. and Spuler, S.
Nature Communications 10 (1): 5776. 18 December 2019

R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.
Harnack, C. and Berger, H. and Antanaviciute, A. and Vidal, R. and Sauer, S. and Simmons, A. and Meyer, T.F. and Sigal, M.
Nature Communications 10 (1): 4368. 25 September 2019

A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding.
Hernáez, B. and Alonso-Lobo, J.M. and Montanuy, I. and Fischer, C. and Sauer, S. and Sigal, L. and Sevilla, N. and Alcamí, A.
Nature Communications 9 (1): 5440. 21 December 2018

Perturbation-response genes reveal signaling footprints in cancer gene expression.
Schubert, M. and Klinger, B. and Klünemann, M. and Sieber, A. and Uhlitz, F. and Sauer, S. and Garnett, M.J. and Blüthgen, N. and Saez-Rodriguez, J.
Nature Communications 9 (1): 20. 2 January 2018

Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3.
Van Haute, L. and Dietmann, S. and Kremer, L. and Hussain, S. and Pearce, S.F. and Powell, C.A. and Rorbach, J. and Lantaff, R. and Blanco, S. and Sauer, S. and Kotzaeridou, U. and Hoffmann, G.F. and Memari, Y. and Kolb-Kokocinski, A. and Durbin, R. and Mayr, J.A. and Frye, M. and Prokisch, H. and Minczuk, M.
Nature Communications 7 : 12039. 30 June 2016

Serial interactome capture of the human cell nucleus.
Conrad, T. and Albrecht, A.-S. and Rodrigues de Melo Costa, V. and Sauer, S. and Meierhofer, D. and Ørom, U.A.
Nature Communications 7 : 11212. 4 April 2016

Nature Genetics

Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González, R. and Conrad, T. and Stöber, M.C. and Xu, R. and Giurgiu, M. and Rodriguez-Fos, E. and Kasack, K. and Brückner, L. and van Leen, E. and Helmsauer, K. and Dorado Garcia, H. and Stefanova, M.E. and Hung, K.L. and Bei, Y. and Schmelz, K. and Lodrini, M. and Mundlos, S. and Chang, H.Y. and Deubzer, H.E. and Sauer, S. and Eggert, A. and Schulte, J.H. and Schwarz, R.F. and Haase, K. and Koche, R.P. and Henssen, A.G.
Nature Genetics 55 (5): 880-890. May 2023

Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Koche, R.P. and Rodriguez-Fos, E. and Helmsauer, K. and Burkert, M. and MacArthur, I.C. and Maag, J. and Chamorro, R. and Munoz-Perez, N. and Puiggròs, M. and Dorado Garcia, H. and Bei, Y. and Röefzaad, C. and Bardinet, V. and Szymansky, A. and Winkler, A. and Thole, T. and Timme, N. and Kasack, K. and Fuchs, S. and Klironomos, F. and Thiessen, N. and Blanc, E. and Schmelz, K. and Künkele, A. and Hundsdörfer, P. and Rosswog, C. and Theissen, J. and Beule, D. and Deubzer, H. and Sauer, S. and Toedling, J. and Fischer, M. and Hertwig, F. and Schwarz, R.F. and Eggert, A. and Torrents, D. and Schulte, J.H. and Henssen, A.G.
Nature Genetics 52 (1): 29-34. January 2020

Nature Methods

A Y2H-seq approach defines the human protein methyltransferase interactome.
Weimann, M. and Grossmann, A. and Woodsmith, J. and Özkan, Z. and Birth, P. and Meierhofer, D. and Benlasfer, N. and Valovka, T. and Timmermann, B. and Wanker, E.E. and Sauer, S. and Stelzl, U.
Nature Methods 10 (4): 339-342. April 2013

Nature Protocols

Phylogenetic classification and identification of bacteria by mass spectrometry.
Freiwald, A. and Sauer, S.
Nature Protocols 4 (5): 732-742. 23 April 2009

Single-nucleotide polymorphisms: analysis by mass spectrometry.
Sauer, S. and Reinhardt, R. and Lehrach, H. and Gut, I.G.
Nature Protocols 1 (4): 1761-1771. 22 November 2006

Nature Reviews Genetics

Miniaturization in functional genomics and proteomics.
Sauer, S. and Lange, B.M.H. and Gobom, J. and Nyarsik, L. and Seitz, H. and Lehrach, H.
Nature Reviews Genetics 6 (6): 465-764. 1 June 2005

Nature Reviews Microbiology

Mass spectrometry tools for the classification and identification of bacteria.
Sauer, S. and Kliem, M.
Nature Reviews Microbiology 8 (1): 74-82. 1 January 2010

New Biotechnology

New technologies for DNA analysis - a review of the READNA project.
McGinn, S. and Bauer, D. and Brefort, T. and Dong, L. and El-Sagheer, A. and Elsharawy, A. and Evans, G. and Falk-Sörqvist, E. and Forster, M. and Fredriksson, S. and Freeman, P. and Freitag, C. and Fritzsche, J. and Gibson, S. and Gullberg, M. and Gut, M. and Heath, S. and Heath-Brun, I. and Heron, A.J. and Hohlbein, J. and Ke, R. and Lancaster, O. and Le Reste, L. and Maglia, G. and Marie, R. and Mauger, F. and Mertes, F. and Mignardi, M. and Moens, L. and Oostmeijer, J. and Out, R. and Pedersen, J.N. and Persson, F. and Picaud, V. and Rotem, D. and Schracke, N. and Sengenes, J. and Stähler, P.F. and Stade, B. and Stoddart, D. and Teng, X. and Veal, C.D. and Zahra, N. and Bayley, H. and Beier, M. and Brown, T. and Dekker, C. and Ekström, B. and Flyvbjerg, H. and Franke, A. and Guenther, S. and Kapanidis, A.N. and Kaye, J. and Kristensen, A. and Lehrach, H. and Mangion, J. and Sauer, S. and Schyns, E. and Tost, J. and van Helvoort, J.M.L.M. and van der Zaag, P.J. and Tegenfeldt, J.O. and Brookes, A.J. and Mir, K. and Nilsson, M. and Willcocks, J.P. and Gut, I.G.
New Biotechnology 33 (3): 311-330. 25 May 2016

Quantification of target proteins using hydrogel antibody arrays and MALDI time-of-flight mass spectrometry (A2M2S).
Darii, E. and Lebeau, D. and Papin, N. and Rubina, A.Y. and Stomakhin, A. and Tost, J. and Sauer, S. and Savvateeva, E. and Dementieva, E. and Zasedatelev, A. and Makarov, A.A. and Gut, I.G.
New Biotechnology 25 (6): 404-416. 15 September 2009

Nucleic Acids Research

The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages.
Daniel, B. and Nagy, G. and Horvath, A. and Czimmerer, Z. and Cuaranta-Monroy, I. and Poliska, S. and Hays, T.T. and Sauer, S. and Francois-Deleuze, J. and Nagy, L.
Nucleic Acids Research 46 (9): 4425-4439. 18 May 2018

Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements.
Telorac, J. and Prykhozhij, S.V. and Schöne, S. and Meierhofer, D. and Sauer, S. and Thomas-Chollier, M. and Meijsing, S.H.
Nucleic Acids Research 44 (13): 6142-6156. 27 July 2016

Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA.
Cui, H. and Schlesinger, J. and Schoenhals, S. and Toenjes, M. and Dunkel, I. and Meierhofer, D. and Cano, E. and Schulz, K. and Berger, M.F. and Haack, T. and Abdelilah-Seyfried, S. and Bulyk, M.L. and Sauer, S. and Sperling, S.R.
Nucleic Acids Research 44 (6): 2538-2553. 7 April 2016

Development of a high-resolution NGS-based HLA-typing and analysis pipeline.
Wittig, M. and Anmarkrud, J.A. and Kässens, J.C. and Koch, S. and Forster, M. and Ellinghaus, E. and Hov, J.R. and Sauer, S. and Schimmler, M. and Ziemann, M. and Görg, S. and Jacob, F. and Karlsen, T.H. and Franke, A.
Nucleic Acids Research 43 (11): e70. 23 June 2015

Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells.
Feldmann, R. and Fischer, C. and Kodelja, V. and Behrens, S. and Haas, S. and Vingron, M. and Timmermann, B. and Geikowski, A. and Sauer, S.
Nucleic Acids Research 41 (6): 3518-3531. April 2013

MALDI mass spectrometry analysis of single nucleotide polymorphisms by photocleavage and charge-tagging.
Sauer, S. and Lehrach, H. and Reinhardt, R.
Nucleic Acids Research 31 (11): e63. 1 June 2003

Facile method for automated genotyping of single nucleotide polymorphisms by mass spectrometry.
Sauer, S. and Gelfand, D.H. and Boussicault, F. and Bauer, K. and Reichert, F. and Gut, I.G.
Nucleic Acids Research 30 (5): e22. 1 March 2002

Full flexibility genotyping of single nucleotide polymorphisms by the GOOD assay.
Sauer, S. and Lechner, D. and Berlin, K. and Plançon, C. and Heuermann, A. and Lehrach, H. and Gut, I.G.
Nucleic Acids Research 28 (23): e100. 1 December 2000

A novel procedure for efficient genotyping of single nucleotide polymorphisms.
Sauer, S. and Lechner, D. and Berlin, K. and Lehrach, H. and Escary, J.L. and Fox, N. and Gut, I.G.
Nucleic Acids Research 28 (5): e13. 1 March 2000

Nutrition

Intestinal expression of toll-like receptor gene changes early after gastric bypass surgery and association with type 2 diabetes remission.
Sala, P. and Torrinhas, R.S.M.M. and Fonseca, D.C. and Machado, N.M. and Singer, J. and Singer, P. and Ravacci, G.R. and Belarmino, G. and Ferreira, B.A.M. and Marques, M. and Ishida, R.K. and Guarda, I.F.M.S. and de Moura, E.G.H. and Sakai, P. and Santo, M.A. and Sunaga, D.Y. and Heymsfield, S.B. and Bezerra, D.P.D.S. and Corrêa-Giannella, M.L. and Waitzberg, D.L.
Nutrition 79-80 : 110885. November 2020

OncoImmunology

Interferon regulatory factor 4 plays a pivotal role in the development of aGVHD-associated colitis.
Frueh, J.T. and Campe, J. and Sunaga-Franze, D.Y. and Verheyden, N.A. and Ghimire, S. and Meedt, E. and Haslinger, D. and Harenkamp, S. and Staudenraus, D. and Sauer, S. and Kreft, A. and Schubert, R. and Lohoff, M. and Krueger, A. and Bonig, H. and Chiocchetti, A.G. and Zeiser, R. and Holler, E. and Ullrich, E.
OncoImmunology 13 (1): 2296712. 2024

Oncotarget

The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation.
Vučićević, D. and Gehre, M. and Dhamija, S. and Friis-Hansen, L. and Meierhofer, D. and Sauer, S. and Ørom, U.A.
Oncotarget 7 (23): 33934-33947. 7 June 2016

Organic Letters

A common building block for the syntheses of amorfrutin and cajaninstilbene acid libraries toward efficient binding with peroxisome proliferator-activated receptors.
Aidhen, I.S. and Mukkamala, R. and Weidner, C. and Sauer, S.
Organic Letters 17 (2): 194-197. 16 January 2015

PLOS ONE

Analysis of expressed genes of the bacterium 'Candidatus Phytoplasma mali' highlights key features of virulence and metabolism.
Siewert, C. and Luge, T. and Duduk, B. and Seemüller, E. and Büttner, C. and Sauer, S. and Kube, M.
PLOS ONE 9 (4): e94391. 11 April 2014

Antidiabetic effects of chamomile flowers extract in obese mice through transcriptional stimulation of nutrient sensors of the peroxisome proliferator-activated receptor (PPAR) family.
Weidner, C. and Wowro, S.J. and Rousseau, M. and Freiwald, A. and Kodelja, V. and Abdel-Aziz, H. and Kelber, O. and Sauer, S.
PLOS ONE 8 (11): e80335. 12 November 2013

Foam cell specific LXRα ligand.
Feldmann, R. and Geikowski, A. and Weidner, C. and Witzke, A. and Kodelja, V. and Schwarz, T. and Gabriel, M. and Erker, T. and Sauer, S.
PLOS ONE 8 (2): e57311. 25 February 2013

Classification and identification of bacteria by mass spectrometry and computational analysis.
Sauer, S. and Freiwald, A. and Maier, T. and Kube, M. and Reinhardt, R. and Kostrzewa, M. and Geider, K.
PLOS ONE 3 (7): e2843. 30 July 2008

PLoS Neglected Tropical Diseases

Deep sequencing of the trypanosoma cruzi GP63 surface proteases reveals diversity and diversifying selection among chronic and congenital Chagas disease patients.
Llewellyn, M.S. and Messenger, L.A. and Luquetti, A.O. and Garcia, L. and Torrico, F. and Tavares, S.B.N. and Cheaib, B. and Derome, N. and Delepine, M. and Baulard, C. and Deleuze, J.F. and Sauer, S. and Miles, M.A.
PLoS Neglected Tropical Diseases 9 (4): e0003458. 7 April 2015

PLoS ONE

Iberis amara extract induces intracellular formation of reactive oxygen species and inhibits colon cancer.
Weidner, C. and Rousseau, M. and Plauth, A. and Wowro, S.J. and Fischer, C. and Abdel-Aziz, H. and Sauer, S.
PLoS ONE 11 (4): e0152398. 6 April 2016

Analysis of genes involved in body weight regulation by targeted re-sequencing.
Volckmar, A.L. and Han, C.T. and Pütter, C. and Haas, S. and Vogel, C.I.G. and Knoll, N. and Struve, C. and Göbel, M. and Haas, K. and Herrfurth, N. and Jarick, I. and Grallert, H. and Schürmann, A. and Al-Hasani, H. and Hebebrand, J. and Sauer, S. and Hinney, A.
PLoS ONE 11 (2): e0147904. 1 February 2016

Phytomedicine

Melissa officinalis extract induces apoptosis and inhibits proliferation in colon cancer cells through formation of reactive oxygen species.
Weidner, C. and Rousseau, M. and Plauth, A. and Wowro, S.J. and Fischer, C. and Abdel-Aziz, H. and Sauer, S.
Phytomedicine 22 (2): 262-270. 15 February 2015

Plant Journal

Single-nuclei RNA-sequencing of plant tissues using a nanowell-based system.
Sunaga-Franze, D. and Muino, J.M. and Braeuning, C. and Xu, X. and Zong, M. and Smaczniak, C. and Yan, W. and Fischer, C. and Vidal, R. and Kliem, M. and Kaufmann, K. and Sauer, S.
Plant Journal 108 (3): 859-869. 5 November 2021

Proceedings of the National Academy of Sciences of the United States of America

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J. and Grinat, J. and Kosel, F. and Liu, L. and Kunz, S. and Vidal, R.O. and Keil, M. and Haybaeck, J. and Robine, S. and Louvard, D. and Regenbrecht, C. and Sporbert, A. and Sauer, S. and von Eyss, B. and Sigal, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 118 (22): e2019699118. 1 June 2021

Amorfrutins are potent antidiabetic dietary natural products.
Weidner, C. and de Groot, J.C. and Prasad, A. and Freiwald, A. and Quedenau, C. and Kliem, M. and Witzke, A. and Kodelja, V. and Han, C.T. and Giegold, S. and Baumann, M. and Klebl, B. and Siems, K. and Müller-Kuhrt, L. and Schürmann, A. and Schüler, R. and Pfeiffer, A.F.H. and Schroeder, F.C. and Büssow, K. and Sauer, S.
Proceedings of the National Academy of Sciences of the United States of America 109 (19): 7257-7262. 8 May 2012

Proteomics

Nutriproteomics: facts, concepts, and perspectives.
Sauer, S. and Luge, T.
Proteomics 15 (5-6): 997-1013. March 2015

Transcriptomics assisted proteomic analysis of Nicotiana occidentalis infected by Candidatus Phytoplasma mali strain AT.
Luge, T. and Kube, M. and Freiwald, A. and Meierhofer, D. and Seemüller, E. and Sauer, S.
Proteomics 14 (16): 1882-1889. August 2014

Comprehensive proteomic data sets for studying adipocyte-macrophage cell-cell communication.
Freiwald, A. and Weidner, C. and Witzke, A. and Huang, S.Y. and Meierhofer, D. and Sauer, S.
Proteomics 13 (23-24): 3424-3428. December 2013

Proteomics Clinical Applications

Diagnostic proteomics: will this impact the clinic?
Sauer, S.
Proteomics Clinical Applications 7 (11-12): 725-726. December 2013

RNA

Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing.
Conrad, T. and Ntini, E. and Lang, B. and Cozzuto, L. and Andersen, J.B. and Marquardt, J.U. and Ponomarenko, J. and Tartaglia, G.G. and Vang Orom, U.A.
RNA 26 (11): 1726-1730. November 2020

RNA Biology

Organ-specific small non-coding RNA responses in domestic (Sudani) ducks experimentally infected with highly pathogenic avian influenza virus (H5N1).
Samir, M. and Vidal, R.O. and Abdallah, F. and Capece, V. and Seehusen, F. and Geffers, R. and Hussein, A. and Ali, A.A.H. and Bonn, S. and Pessler, F.
RNA Biology 17 (1): 112-124. January 2020

Rapid Communications in Mass Spectrometry

Multiplexed hybridizations of positively charge-tagged peptide nucleic acids detected by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Bauer, O. and Guerasimova, A. and Sauer, S. and Thamm, S. and Steinfath, M. and Herwig, R. and Janitz, M. and Lehrach, H. and Radelof, U.
Rapid Communications in Mass Spectrometry 18 (16): 1821-1829. 30 August 2004

Extension of the GOOD assay for genotyping single nucleotide polymorphisms by matrix-assisted laser desorption/ionization mass spectrometry.
Sauer, S. and Gut, I.G.
Rapid Communications in Mass Spectrometry 17 (12): 1265-1272. 30 June 2003

Redox Biology

Effects of diets high in animal or plant protein on oxidative stress in individuals with type 2 diabetes: a randomized clinical trial.
Pivovarova-Ramich, O. and Markova, M. and Weber, D. and Sucher, S. and Hornemann, S. and Rudovich, N. and Raila, J. and Sunaga-Franze, D. and Sauer, S. and Rohn, S. and Pfeiffer, A.F.H. and Grune, T.
Redox Biology 29 (2): 101397. January 2020

Research Square

Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and development.
Freitag, K. and Eede, P. and Ivanov, A. and Schneeberger, S. and Borodina, T. and Sauer, S. and Beule, D. and Heppner, F.
Research Square : rs.3.rs-1362379/v1. 28 February 2022

Science Advances

Viral cGAMP nuclease reveals the essential role of DNA sensing in protection against acute lethal virus infection.
Hernáez, B. and Alonso, G. and Georgana, I. and El-Jesr, M. and Martín, R. and Shair, K.H.Y. and Fischer, C. and Sauer, S. and Maluquer de Motes, C. and Alcamí, A.
Science Advances 6 (38): eabb4565. 18 September 2020

Science Signaling

Signals trigger state-specific transcriptional programs to support diversity and homeostasis in immune cells.
Fischer, C. and Metsger, M. and Bauch, S. and Vidal, R. and Böttcher, M. and Grote, P. and Kliem, M. and Sauer, S.
Science Signaling 12 (581): eaao5820. 14 May 2019

Science of the Total Environment

Urbanization promotes specific bacteria in freshwater microbiomes including potential pathogens.
Numberger, D. and Zoccarato, L. and Woodhouse, J. and Ganzert, L. and Sauer, S. and García Márquez, J.R. and Domisch, S. and Grossart, H.P. and Greenwood, A.D.
Science of the Total Environment 845 : 157321. 1 November 2022

Scientific Reports

Characterization of bacterial communities in wastewater with enhanced taxonomic resolution by full-length 16S rRNA sequencing.
Numberger, D. and Ganzert, L. and Zoccarato, L. and Mühldorfer, K. and Sauer, S. and Grossart, H.P. and Greenwood, A.D.
Scientific Reports 9 (1): 9673. 4 July 2019

Signatures of personality on dense 3D facial images.
Hu, S. and Xiong, J. and Fu, P. and Qiao, L. and Tan, J. and Jin, L. and Tang, K.
Scientific Reports 7 (1): 73. March 2017

Stem Cells

PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology.
Simandi, Z. and Czipa, E. and Horvath, A. and Koszeghy, A. and Bordas, C. and Póliska, S. and Juhász, I. and Imre, L. and Szabó, G. and Dezso, B. and Barta, E. and Sauer, S. and Karolyi, K. and Kovacs, I. and Hutóczki, G. and Bognár, L. and Klekner, A. and Szucs, P. and Bálint, B.L. and Nagy, L.
Stem Cells 33 (3): 726-741. March 2015

Theoretical and Applied Genetics

Association mapping reveals gene action and interactions in the determination of flowering time in barley.
Stracke, S. and Haseneyer, G. and Veyrieras, J.B. and Geiger, H.H. and Sauer, S. and Graner, A. and Piepho, H.P.
Theoretical and Applied Genetics 118 (2): 259-273. January 2009

High level of conservation between genes coding for the GAMYB transcription factor in barley (Hordeum vulgare L.) and bread wheat (Triticum aestivum L.) collections.
Haseneyer, G. and Ravel, C. and Dardevet, M. and Balfourier, F. and Sourdille, P. and Charmet, G. and Brunel, D. and Sauer, S. and Geiger, H.H. and Graner, A. and Stracke, S.
Theoretical and Applied Genetics 117 (3): 321-331. August 2008

Trends in Pharmacological Sciences

Ligands for the nuclear peroxisome proliferator-activated receptor gamma.
Sauer, S.
Trends in Pharmacological Sciences 36 (10): 688-704. October 2015

bioRxiv

Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and aging.
Freitag, K. and Eede, P. and Ivanov, A. and Schneeberger, S. and Borodina, T. and Sauer, S. and Beule, D. and Heppner, F.L.
bioRxiv : 2021.08.02.454573v1. 28 November 2021

Urbanization promotes specific bacteria in freshwater microbiomes including potential pathogens.
Numberger, D. and Zoccarato, L. and Woodhouse, J. and Ganzert, L. and Sauer, S. and Grossart, H.P. and Greenwood, A.D.
bioRxiv : 2020.06.26.173328. 8 November 2021

The neuroinflammatory interleukin-12 signaling pathway drives Alzheimer's disease-like pathology by perturbing oligodendrocyte survival and neuronal homeostasis.
Schneeberger, S. and Kim, S.J. and Eede, P. and Boltengagen, A. and Braeuning, C. and Andreadou, M. and Becher, B. and Karaiskos, N. and Kocks, C. and Rajewsky, N. and Heppner, F.L.
bioRxiv : 2021.04.25.441313. 27 April 2021

Single-nuclei RNA-sequencing of plants.
Sunaga-Franze, D.Y. and Muino, J.M. and Braeuning, C. and Xu, X. and Zong, M. and Smaczniak, C. and Yan, W. and Fischer, C. and Vidal, R. and Kliem, M. and Kaufmann, K. and Sauer, S.
bioRxiv : 2020.11.14.382812. 16 November 2020

Regional expression profiles of risk genes for depression are associated with brain activation patterns in emotion and reward tasks.
Komorowski, A. and Vidal, R. and Singh, A. and Murgaš, M. and Pena-Centeno, T. and Gryglewski, G. and Kasper, S. and Wiltfang, J. and Lanzenberger, R. and Goya-Maldonado, R.
bioRxiv : 2020.06.27.175257. 27 June 2020

Dissecting HSV-1-induced host shut-off at RNA level.
Friedel, C.C. and Whisnant, A.W. and Djakovic, L. and Rutkowski, A.J. and Friedl, M.S. and Kluge, M. and Williamson, J.C. and Sai, S. and Oliveira Vidal, R. and Sauer, S. and Hennig, T. and Prusty, B. and Lehner, P.J. and Matheson, N.J. and Erhard, F. and Dölken, L.
bioRxiv : 2020.05.20.106039. 20 May 2020

Single cell RNA-sequencing-based analysis of CD4(+) T-cell subset-specific susceptibility to transcriptional modulation by HIV-1 latency-reversing agents.
Kazmierski, J. and Postmus, D. and Wyler, E. and Fischer, C. and Jansen, J. and Meixenberger, K. and Vitcetz, S.N. and Sohn, M. and Sauer, S. and Bannert, N. and Landthaler, M. and Goffinet, C.
bioRxiv : 2020.05.04.075119. 5 May 2020

Resolving fate and transcriptome of hematopoietic stem cell clones.
Pei, W. and Shang, F. and Wang, X. and Fanti, A.K. and Greco, A. and Busch, K. and Klapproth, K. and Zhang, Q. and Quedenau, C. and Sauer, S. and Feyerabend, T.B. and Höfer, T. and Rodewald, H.R.
bioRxiv : 2020.03.25.008433. 26 March 2020

Chromatin accessibility is dynamically regulated across C. elegans development and ageing.
Janes, J. and Dong, Y. and Schoof, M. and Serizay, J. and Appert, A. and Cerrato, C. and Woodbury, C. and Chen, R. and Gemma, C. and Huang, N. and Kissiov, D. and Stempor, P. and Steward, A. and Zeiser, E. and Sauer, S. and Ahringer, J.
bioRxiv : 279158. 10 June 2018

De novo mutations implicate novel genes with burden of rare variants in systemic lupus erythematosus.
Pullabhatla, V. and Roberts, A.L. and Lewis, M.J. and Mauro, D. and Morris, D.L. and Odhams, C.A. and Tombleson, P. and Liljedahld, U. and Vyse, S. and Simpson, M.A. and Sauer, S. and de Rinaldis, E. and Syvaenen, A.C. and Vyse, T.J.
bioRxiv : 139238. 14 August 2017

Hormetic shifting of redox environment by pro-oxidative resveratrol protects cells against stress.
Plauth, A. and Geikowski, A. and Cichon, S. and Wowro, S.J. and Liedgens, L. and Rousseau, M. and Weidner, C. and Fuhr, L. and Kliem, M. and Jenkins, G. and Lotito, S. and Wainwright, L.J. and Sauer, S.
bioRxiv : 045567. 24 March 2016

eLife

Chromatin accessibility dynamics across C. elegans development and ageing.
Jänes, J. and Dong, Y. and Schoof, M. and Serizay, J. and Appert, A. and Cerrato, C. and Woodbury, C. and Chen, R. and Gemma, C. and Huang, N. and Kissiov, D. and Stempor, P. and Steward, A. and Zeiser, E. and Sauer, S. and Ahringer, J.
eLife 7 : e37344. 26 October 2018

iScience

Long and repeat-rich intronic sequences favor circular RNA formation under conditions of reduced spliceosome activity.
Wang, M. and Hou, J. and Müller-McNicoll, M. and Chen, W. and Schuman, E.M.
iScience 20 : 237-247. 25 October 2019