2025
Reprogramming-driven drug discovery uncovers sildenafil as a candidate drug for mitochondrial disease.
Prigione, Alessandro
ORCID: https://orcid.org/0000-0001-9457-1952
[Dataset]
21 February 2025
2022
Generation of induced pluripotent stem cells from three individuals with Huntington's disease.
Miller, D.C.
ORCID: https://orcid.org/0000-0001-9852-677X, Lisowski, P.
ORCID: https://orcid.org/0000-0002-3634-1072, Lickfett, S., Mlody, B.
ORCID: https://orcid.org/0000-0001-5184-1772, Bünning, M., Genehr, C., Ulrich, C., Wanker, E.E.
ORCID: https://orcid.org/0000-0001-8072-1630, Diecke, S.
ORCID: https://orcid.org/0000-0002-5219-5992, Priller, J.
ORCID: https://orcid.org/0000-0001-7596-0979 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Stem Cell Research 65
: 102976.
December 2022
Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6.
Lorenz, C.
ORCID: https://orcid.org/0000-0002-7762-8133, Zink, A.
ORCID: https://orcid.org/0000-0002-8489-6339, Henke, M.T.
ORCID: https://orcid.org/0000-0001-6572-1667, Staege, S., Mlody, B.
ORCID: https://orcid.org/0000-0001-5184-1772, Bünning, M., Wanker, E.
ORCID: https://orcid.org/0000-0001-8072-1630, Diecke, S.
ORCID: https://orcid.org/0000-0002-5219-5992, Schuelke, M.
ORCID: https://orcid.org/0000-0003-2824-3891 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Stem Cell Research 61
: 102742.
May 2022
2021
Mitochondria in neurogenesis: implications for mitochondrial diseases.
Brunetti, D.
ORCID: https://orcid.org/0000-0002-2740-9370, Dykstra, W.
ORCID: https://orcid.org/0000-0002-7663-4689, Le, S., Zink, A.
ORCID: https://orcid.org/0000-0002-8489-6339 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Stem Cells 39
(10): 1289-1297.
October 2021
Generation of human brain organoids for mitochondrial disease modeling.
Le, S., Petersilie, L., Inak, G., Menacho-Pando, C., Kafitz, K.W., Rybak-Wolf, A.
ORCID: https://orcid.org/0000-0002-1192-5290, Rajewsky, N.
ORCID: https://orcid.org/0000-0002-4785-4332, Rose, C.R. and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Journal of Visualized Experiments
(172): e62756.
21 June 2021
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak, G., Rybak-Wolf, A.
ORCID: https://orcid.org/0000-0002-1192-5290, Lisowski, P.
ORCID: https://orcid.org/0000-0002-3634-1072, Pentimalli, T.M.
ORCID: https://orcid.org/0000-0002-8461-7918, Jüttner, R.
ORCID: https://orcid.org/0000-0003-3565-0698, Glažar, P.
ORCID: https://orcid.org/0000-0003-0842-0088, Uppal, K., Bottani, E.
ORCID: https://orcid.org/0000-0003-1217-8722, Brunetti, D.
ORCID: https://orcid.org/0000-0002-2740-9370, Secker, C.
ORCID: https://orcid.org/0000-0002-7222-536X, Zink, A.
ORCID: https://orcid.org/0000-0002-8489-6339, Meierhofer, D.
ORCID: https://orcid.org/0000-0002-0170-868X, Henke, M.T.
ORCID: https://orcid.org/0000-0001-6572-1667, Dey, M.
ORCID: https://orcid.org/0000-0002-9987-575X, Ciptasari, U.
ORCID: https://orcid.org/0000-0003-4577-3069, Mlody, B.
ORCID: https://orcid.org/0000-0001-5184-1772, Hahn, T., Berruezo-Llacuna, M., Karaiskos, N.
ORCID: https://orcid.org/0000-0001-7771-3947, Di Virgilio, M.
ORCID: https://orcid.org/0000-0001-5189-0793, Mayr, J.A.
ORCID: https://orcid.org/0000-0001-6970-336X, Wortmann, S.B., Priller, J.
ORCID: https://orcid.org/0000-0001-7596-0979, Gotthardt, M.
ORCID: https://orcid.org/0000-0003-1788-3172, Jones, D.P., Mayatepek, E., Stenzel, W., Diecke, S.
ORCID: https://orcid.org/0000-0002-5219-5992, Kühn, R.
ORCID: https://orcid.org/0000-0003-1694-9803, Wanker, E.E.
ORCID: https://orcid.org/0000-0001-8072-1630, Rajewsky, N.
ORCID: https://orcid.org/0000-0002-4785-4332, Schuelke, M.
ORCID: https://orcid.org/0000-0003-2824-3891 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Nature Communications 12
(1): 1929.
26 March 2021
Generation of human iPSC-derived neural progenitor cells (NPCs) as drug discovery model for neurological and mitochondrial disorders.
Zink, A.
ORCID: https://orcid.org/0000-0002-8489-6339, Lisowski, P.
ORCID: https://orcid.org/0000-0002-3634-1072 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Bio-protocol 11
(5): e3939.
5 March 2021
2020
Assessment of ethanol-induced toxicity on iPSC-derived human dopaminergic neurons using a novel high-throughput mitochondrial neuronal health (MNH) assay.
Zink, A.
ORCID: https://orcid.org/0000-0002-8489-6339, Conrad, J., Telugu, N.S.
ORCID: https://orcid.org/0000-0003-4509-7056, Diecke, S.
ORCID: https://orcid.org/0000-0002-5219-5992, Heinz, A., Wanker, E.
ORCID: https://orcid.org/0000-0001-8072-1630, Priller, J.
ORCID: https://orcid.org/0000-0001-7596-0979 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Frontiers in Cell and Developmental Biology 8
: 590540.
5 November 2020
PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V.
ORCID: https://orcid.org/0000-0002-0077-1935, Berruezo-Llacuna, M., Altwasser, R.
ORCID: https://orcid.org/0009-0002-6216-6068, Winkler, W.
ORCID: https://orcid.org/0000-0001-8807-9259, Sundaravinayagam, D.
ORCID: https://orcid.org/0000-0003-0717-7530, Balasubramanian, S.
ORCID: https://orcid.org/0000-0003-1830-5737, Caganova, M.
ORCID: https://orcid.org/0000-0002-4576-6574, Graf, R.
ORCID: https://orcid.org/0000-0002-5400-9938, Rahjouei, A.
ORCID: https://orcid.org/0000-0003-3973-6333, Henke, M.T.
ORCID: https://orcid.org/0000-0001-6572-1667, Driesner, M., Keller, L., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117 and Di Virgilio, M.
ORCID: https://orcid.org/0000-0001-5189-0793
Journal of Experimental Medicine 217
(10): e20200137.
5 October 2020
Tackling mitochondrial diversity in brain function: from animal models to human brain organoids.
Menacho, C. and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
International Journal of Biochemistry and Cell Biology 123
: 105760.
June 2020
Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery.
Laidou, S., Alanis-Lobato, G., Pribyl, J., Raskó, T.
ORCID: https://orcid.org/0000-0001-5351-613X, Tichy, B., Mikulasek, K., Tsagiopoulou, M., Oppelt, J., Kastrinaki, G., Lefaki, M., Singh, M.
ORCID: https://orcid.org/0000-0002-8626-5418, Zink, A.
ORCID: https://orcid.org/0000-0002-8489-6339, Chondrogianni, N., Psomopoulos, F., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Ivics, Z.
ORCID: https://orcid.org/0000-0002-7803-6658, Pospisilova, S., Skladal, P., Izsvák, Z.
ORCID: https://orcid.org/0000-0002-2053-2384, Andrade-Navarro, M.A. and Petrakis, S.
Redox Biology 32
: 101458.
May 2020
2019
Live-imaging readouts and cell models for phenotypic profiling of mitochondrial function.
Iannetti, E.F., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Smeitink, J.A.M., Koopman, W.J.H., Beyrath, J. and Renkema, H.
Frontiers in Genetics 10
: 131.
March 2019
Novel calcineurin A (PPP3CA) variant associated with epilepsy, constitutive enzyme activation and downregulation of protein expression.
Rydzanicz, M., Wachowska, M., Cook, E.C., Lisowski, P.
ORCID: https://orcid.org/0000-0002-3634-1072, Kuźniewska, B., Szymańska, K., Diecke, S.
ORCID: https://orcid.org/0000-0002-5219-5992, Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Szczałuba, K., Szybińska, A., Koppolu, A., Murcia Pienkowski, V., Kosińska, J., Wiweger, M., Kostrzewa, G., Brzozowska, M., Domańska-Pakieła, D., Jurkiewicz, E., Stawiński, P., Gromadka, A., Zielenkiewicz, P., Demkow, U., Dziembowska, M., Kuźnicki, J., Creamer, T.P. and Płoski, R.
European Journal of Human Genetics 27
(1): 61-69.
January 2019
2018
Mitochondria and the dynamic control of stem cell homeostasis.
Lisowski, P.
ORCID: https://orcid.org/0000-0002-3634-1072, Kannan, P., Mlody, B.
ORCID: https://orcid.org/0000-0001-5184-1772 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
EMBO Reports 19
(5): e45432.
1 May 2018
Pluripotent stem cells for uncovering the role of mitochondria in human brain function and dysfunction.
Zink, A.
ORCID: https://orcid.org/0000-0002-8489-6339, Priller, J.
ORCID: https://orcid.org/0000-0001-7596-0979 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Journal of Molecular Biology 430
(7): 891-903.
30 March 2018
Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex.
Scior, A., Buntru, A., Arnsburg, K., Ast, A.
ORCID: https://orcid.org/0000-0002-2312-1257, Iburg, M., Juenemann, K., Pigazzini, M.L., Mlody, B.
ORCID: https://orcid.org/0000-0001-5184-1772, Puchkov, D., Priller, J.
ORCID: https://orcid.org/0000-0001-7596-0979, Wanker, E.E.
ORCID: https://orcid.org/0000-0001-8072-1630, Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952 and Kirstein, J.
ORCID: https://orcid.org/0000-0003-4990-2497
EMBO Journal 37
(2): 282-299.
17 January 2018
Human mesenchymal factors induce rat hippocampal- and human neural stem cell dependent oligodendrogenesis.
Jadasz, J.J.
ORCID: https://orcid.org/0000-0002-5505-4570, Tepe, L., Beyer, F., Samper Agrelo, I., Akkermann, R.
ORCID: https://orcid.org/0000-0003-1583-9987, Spitzhorn, L.S., Silva, M.E., Oreffo, R.O.C., Hartung, H.P., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Rivera, F.J., Adjaye, J. and Kuery, P.
ORCID: https://orcid.org/0000-0002-2654-1126
Glia 66
(1): 145-160.
January 2018
2017
Mitochondrial metabolism in early neural fate and its relevance for neuronal disease modeling.
Lorenz, C.
ORCID: https://orcid.org/0000-0002-7762-8133 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Current Opinion in Cell Biology 49
: 71-76.
December 2017
Concise review: Induced pluripotent stem cell-based drug discovery for mitochondrial disease.
Inak, G., Lorenz, C.
ORCID: https://orcid.org/0000-0002-7762-8133, Lisowski, P.
ORCID: https://orcid.org/0000-0002-3634-1072, Zink, A.
ORCID: https://orcid.org/0000-0002-8489-6339, Mlody, B.
ORCID: https://orcid.org/0000-0001-5184-1772 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Stem Cells 35
(7): 1655-1662.
July 2017
Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders.
Lorenz, C.
ORCID: https://orcid.org/0000-0002-7762-8133, Lesimple, P.
ORCID: https://orcid.org/0000-0001-9754-6103, Bukowiecki, R., Zink, A.
ORCID: https://orcid.org/0000-0002-8489-6339, Inak, G., Mlody, B.
ORCID: https://orcid.org/0000-0001-5184-1772, Singh, M.
ORCID: https://orcid.org/0000-0002-8626-5418, Semtner, M.
ORCID: https://orcid.org/0000-0001-9379-9023, Mah, N.
ORCID: https://orcid.org/0000-0002-1240-8076, Auré, K., Leong, M., Zabiegalov, O., Lyras, E.M.
ORCID: https://orcid.org/0000-0003-3269-0854, Pfiffer, V., Fauler, B., Eichhorst, J., Wiesner, B., Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Priller, J.
ORCID: https://orcid.org/0000-0001-7596-0979, Mielke, T., Meierhofer, D.
ORCID: https://orcid.org/0000-0002-0170-868X, Izsvák, Z.
ORCID: https://orcid.org/0000-0002-2053-2384, Meier, J.C.
ORCID: https://orcid.org/0000-0001-5574-3336, Bouillaud, F.
ORCID: https://orcid.org/0000-0002-7518-9237, Adjaye, J., Schuelke, M.
ORCID: https://orcid.org/0000-0003-2824-3891, Wanker, E.E.
ORCID: https://orcid.org/0000-0001-8072-1630, Lombès, A.
ORCID: https://orcid.org/0000-0002-9064-0399 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Cell Stem Cell 20
(5): 659-674.e9.
4 May 2017
2016
A movement disorder with dystonia and ataxia caused by a mutation in the HIBCH gene.
Schottmann, G., Sarpong, A., Lorenz, C.
ORCID: https://orcid.org/0000-0002-7762-8133, Weinhold, N., Gill, E., Teschner, L., Ferdinandusse, S., Wanders, R.J.A., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952 and Schuelke, M.
ORCID: https://orcid.org/0000-0003-2824-3891
Movement Disorders 31
(11): 1733-1739.
November 2016
A glycolytic solution for pluripotent stem cells.
Mlody, B.
ORCID: https://orcid.org/0000-0001-5184-1772 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Cell Stem Cell 19
(4): 419-420.
6 October 2016
Aging vs. rejuvenation: reprogramming to iPSCs does not turn back the clock for somatic mitochondrial DNA mutations.
Lorenz, C.
ORCID: https://orcid.org/0000-0002-7762-8133 and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Stem Cell Investigation 3
: 43.
September 2016
A mitochondrial view of cell fate.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Seminars in Cell & Developmental Biology 52
: 66-67.
April 2016
Isolation and cultivation of naive-like human pluripotent stem cells based on HERVH expression.
Wang, J.
ORCID: https://orcid.org/0000-0002-7027-0298, Singh, M., Sun, C., Besser, D.
ORCID: https://orcid.org/0000-0002-4958-9624, Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Ivics, Z.
ORCID: https://orcid.org/0000-0002-7803-6658, Hurst, L.D. and Izsvák, Z.
ORCID: https://orcid.org/0000-0002-2053-2384
Nature Protocols 11
(2): 327-346.
February 2016
2015
Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.
Rohwer, N., Bindel, F., Grimm, C., Lin, S.J., Wappler, J., Klinger, B.
ORCID: https://orcid.org/0000-0003-0242-1506, Blüthgen, N.
ORCID: https://orcid.org/0000-0002-0171-7447, Du Bois, I., Schmeck, B., Lehrach, H., de Graauw, M., Goncalves, E., Saez-Rodriguez, J., Tan, P., Grabsch, H.I., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Kempa, S.
ORCID: https://orcid.org/0000-0002-0696-9299 and Cramer, T.
Oncotarget 7
(6): 6693-6710.
29 December 2015
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway.
Stincone, A., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Cramer, T., Wamelink, M.M.C., Campbell, K., Cheung, E., Olin-Sandoval, V., Gruening, N.M., Krueger, A., Tauqeer Alam, M., Keller, M.A., Breitenbach, M., Brindle, K.M., Rabinowitz, J.D. and Ralser, M.
Biological Reviews 90
(3): 927-963.
August 2015
Metabolic restructuring and cell fate conversion.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Ruiz-Perez, M.V., Bukowiecki, R. and Adjaye, J.
Cellular and Molecular Life Sciences 72
(9): 1759-1777.
1 May 2015
Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer's disease donor as a model for investigating AD-associated gene regulatory networks.
Hossini, A.M., Megges, M.
ORCID: https://orcid.org/0000-0001-6537-0975, Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Lichtner, B., Toliat, M.R., Wruck, W., Schroeter, F., Nuernberg, P., Kroll, H., Makrantonaki, E., Zoubouliss, C.C. and Adjaye, J.
BMC Genomics 16
(1): 84.
14 February 2015
Induced pluripotent stem cells (iPSCs) for modeling mitochondrial DNA disorders.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Methods in Molecular Biology 1265
: 349-356.
6 January 2015
Assessing the bioenergetic profile of human pluripotent stem cells.
Pfiffer, V. and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Methods in Molecular Biology 1264
: 279-288.
2015
2014
Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J.
ORCID: https://orcid.org/0000-0002-7027-0298, Xie, G.
ORCID: https://orcid.org/0000-0002-8286-2987, Singh, M.
ORCID: https://orcid.org/0000-0002-8626-5418, Ghanbarian, A.T., Raskó, T., Szvetnik, A., Cai, H., Besser, D.
ORCID: https://orcid.org/0000-0002-4958-9624, Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Fuchs, N.V.
ORCID: https://orcid.org/0000-0003-4175-0740, Schumann, G.G., Chen, W.
ORCID: https://orcid.org/0000-0003-3263-1627, Lorincz, M.C., Ivics, Z.
ORCID: https://orcid.org/0000-0002-7803-6658, Hurst, L.D. and Izsvák, Z.
ORCID: https://orcid.org/0000-0002-2053-2384
Nature 516
(7531): 405-409.
18 December 2014
A mitochondrial strategy for safeguarding the reprogrammed genome.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952 and Adjaye, J.
Cell Regeneration 3
(1): 5.
29 March 2014
HIF1α modulates reprogramming through early glycolytic shift and up-regulation of PDK1-3 and PKM2.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Rohwer, N., Hoffman, S., Mlody, B., Drews, K., Bukowiecki, R., Bluemlein, K., Wanker, E.E.
ORCID: https://orcid.org/0000-0001-8072-1630, Ralser, M., Cramer, T. and Adjaye, J.
Stem Cells 32
(2): 364-376.
February 2014
Mitochondrial function in pluripotent stem cells and cellular reprogramming.
Bukowiecki, R., Adjaye, J. and Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952
Gerontology 60
(2): 174-182.
February 2014
2013
Teratoma formation of human embryonic stem cells in three-dimensional perfusion culture bioreactors.
Stachelscheid, H., Wulf-Goldenberg, A., Eckert, K., Jensen, J., Edsbagge, J., Bjoerquist, P., Rivero, M., Strehl, R., Jozefczuk, J., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Adjaye, J., Urbaniak, T., Bussmann, P., Zeilinger, K. and Gerlach, J.C.
Journal of Tissue Engineering and Regenerative Medicine 7
(9): 729-741.
September 2013
Transcriptome based identification of mouse cumulus cell markers that predict the developmental competence of their enclosed antral oocytes.
Vigone, G., Merico, V., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Mulas, F., Sacchi, L., Gabetta, M., Bellazzi, R., Redi, C.A., Mazzini, G., Adjaye, J., Garagna, S. and Zuccotti, M.
BMC Genomics 14
: 380.
7 June 2013
Human stromal (mesenchymal) stem cells from bone marrow, adipose tissue and skin exhibit differences in molecular phenotype and differentiation potential.
Al-Nbaheen, M., Vishnubalaji, R., Ali, D., Bouslimi, A., Al-Jassir, F., Megges, M.
ORCID: https://orcid.org/0000-0001-6537-0975, Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Adjaye, J., Kassem, M. and Aldahmash, A.
Stem Cell Reviews and Reports 9
(1): 32-43.
February 2013
2012
Human induced pluripotent stem cells--from mechanisms to clinical applications.
Drews, K., Jozefczuk, J., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952 and Adjaye, J.
Journal of Molecular Medicine 90
(7): 735-745.
July 2012
OCT4 and the acquisition of oocyte developmental competence during folliculogenesis.
Zuccotti, M., Merico, V., Belli, M., Mulas, F., Sacchi, L., Zupan, B., Redi, C.A., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Adjaye, J., Bellazzi, R. and Garagna, S.
International Journal of Developmental Biology 56
(10-12): 853-858.
2012
2011
Mitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrations.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Hossini, A.M., Lichtner, B., Serin, A., Fauler, B., Megges, M.
ORCID: https://orcid.org/0000-0001-6537-0975, Lurz, R., Lehrach, H., Makrantonaki, E., Zouboulis, C.C and Adjaye, J.
PLoS ONE 6
(11): e27352.
14 November 2011
Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Lichtner, B., Kuhl, H., Struys, E.A., Wamelink, M., Lehrach, H., Ralser, M., Timmermann, B. and Adjaye, J.
Stem Cells 29
(9): 1338-1348.
September 2011
Molecular insights into reprogramming-initiation events mediated by the OSKM gene regulatory network.
Mah, N.
ORCID: https://orcid.org/0000-0002-1240-8076, Wang, Y., Liao, M.C., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Jozefczuk, J., Lichtner, B., Wolfrum, K., Haltmeier, M., Floettmann, M., Schaefer, M., Hahn, A., Mrowka, R., Klipp, E., Andrade-Navarro, M.A.
ORCID: https://orcid.org/0000-0001-6650-1711 and Adjaye, J.
PLoS ONE 6
(8): e24351.
31 August 2011
Gatekeeper of pluripotency: a common Oct4 transcriptional network operates in mouse eggs and embryonic stem cells.
Zuccotti, M., Merico, V., Bellone, M., Mulas, F., Sacchi, L., Rebuzzini, P., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Redi, C.A., Bellazzi, R., Adjaye, J. and Garagna, S.
BMC Genomics 12
: 345.
5 July 2011
Comparative analysis of human embryonic stem cell and induced pluripotent stem cell-derived hepatocyte-like cells reveals current drawbacks and possible strategies for improved differentiation.
Jozefczuk, J., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Chavez, L. and Adjaye, J.
Stem Cells and Development 20
(7): 1259-1275.
July 2011
A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease.
Krueger, R., Sharma, M., Riess, O., Gasser, T., Van Broeckhoven, C., Theuns, J., Aasly, J., Annesi, G., Bentivoglio, A.R., Brice, A., Djarmati, A., Elbaz, A., Farrer, M., Ferrarese, C., Gibson, J.M., Hadjigeorgiou, G.M., Hattori, N., Ioannidis, J.P.A., Jasinska-Myga, B., Klein, C., Lambert, J.C., Lesage, S., Lin, J.J., Lynch, T., Mellick, G.D., de Nigris, F., Opala, G., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Quattrone, A., Ross, O.A., Satake, W., Silburn, P.A., Tan, E.K., Toda, T., Tomiyama, H., Wirdefeldt, K., Wszolek, Z., Xiromerisiou, G. and Maraganore, D.M.
Neurobiology of Aging 32
(3): 548.e9-548.e18.
March 2011
2010
An ES-like pluripotent state in FGF-dependent murine iPS cells.
Di Stefano, B., Buecker, C., Ungaro, F., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Chen, H.H., Welling, M., Eijpe, M., Mostoslavsky, G., Tesar, P., Adjaye, J., Geijsen, N. and Broccoli, V.
PLoS ONE 5
(12): e16092.
30 December 2010
The LARGE principle of cellular reprogramming: lost, acquired and retained gene expression in foreskin and amniotic fluid-derived human iPS cells.
Wolfrum, K., Wang, Y., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Sperling, K., Lehrach, H. and Adjaye, J.
PLoS ONE 5
(10): e13703.
29 October 2010
Alpha-synuclein nitration and autophagy response are induced in peripheral blood cells from patients with Parkinson disease.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Piazza, F., Brighina, L., Begni, B., Galbussera, A., DiFrancesco, J.C., Andreoni, S., Piolti, R. and Ferrarese, C.
Neuroscience Letters 477
(1): 6-10.
14 June 2010
A transcriptional roadmap to the induction of pluripotency in somatic cells.
Wang, Y., Mah, N., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Wolfrum, K., Andrade-Navarro, M.A. and Adjaye, J.
Stem Cell Reviews 6
(2): 282-296.
June 2010
Lymphomonocyte alpha-synuclein levels in aging and in Parkinson disease.
Brighina, L., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Begni, B., Galbussera, A., Andreoni, S., Piolti, R. and Ferrarese, C.
Neurobiology of Aging 31
(5): 884-885.
May 2010
The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Fauler, B., Lurz, R., Lehrach, H. and Adjaye, J.
Stem Cells 28
(4): 721-733.
April 2010
Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952 and Adjaye, J.
International Journal of Developmental Biology 54
(11-12): 1729-1741.
2010
2009
Efficient genetic reprogramming of unmodified somatic neural progenitors uncovers the essential requirement of Oct4 and Klf4.
Di Stefano, B., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952 and Broccoli, V.
Stem Cells and Development 18
(5): 707-716.
June 2009
Increased oxidative stress in lymphocytes from untreated Parkinson's disease patients.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Isaias, I.U., Galbussera, A., Brighina, L., Begni, B., Andreoni, S., Pezzoli, G., Antonini, A. and Ferrarese, C.
Parkinsonism & Related Disorders 15
(4): 327-328.
May 2009
2007
Mitochondrial DNA deletions induce the adenosine monophosphate-activated protein kinase energy stress pathway and result in decreased secretion of some proteins.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952 and Cortopassi, G.
Aging Cell 6
(5): 619-630.
October 2007
Mitochondrial DNA deletions and chloramphenicol treatment stimulate the autophagic transcript ATG12.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952 and Cortopassi, G.
Autophagy 3
(4): 377-380.
July 2007
Mitochondrial DNA deletions inhibit proteasomal activity and stimulate an autophagic transcript.
Alemi, M., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Wong, A., Schoenfeld, R., DiMauro, S., Hirano, M., Taroni, F. and Cortopassi, G.
Free Radical Biology and Medicine 42
(1): 32-43.
1 January 2007
2006
Oxidative stress in peripheral blood mononuclear cells from patients with Parkinson's disease: negative correlation with levodopa dosage.
Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Begni, B., Galbussera, A., Beretta, S., Brighina, L., Garofalo, R., Andreoni, S., Piolti, R. and Ferrarese, C.
Neurobiology of Disease 23
(1): 36-43.
July 2006
2004
"What do you remember about Chernobyl?" A new test of memory for media-mediated events.
Bizzozero, I., Lucchelli, F., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Saetti, M.C. and Spinnler, H.
Neurological Sciences 25
(4): 205-215.
October 2004
This list was generated on Sun Jul 12 07:10:03 2026 UTC.