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2018

Evaluation of food allergy candidate loci in the Genetics of Food Allergy Study.
Marenholz, I. and Grosche, S. and Rüschendorf, F. and Kalb, B. and Blumchen, K. and Schlags, R. and Harandi, N. and Price, M. and Hansen, G. and Seidenberg, J. and Yürek, S. and Homuth, G. and Schmidt, C.O. and Nöthen, M.M. and Hubner, N. and Niggemann, B. and Beyer, K. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 142 (4): 1368-1370. October 2018

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.
Waage, J. and Standl, M. and Curtin, J.A. and Jessen, L.E. and Thorsen, J. and Tian, C. and Schoettler, N. and Flores, C. and Abdellaoui, A. and Ahluwalia, T.S. and Alves, A.C. and Amaral, A.F.S. and Antó, J.M. and Arnold, A. and Barreto-Luis, A. and Baurecht, H. and van Beijsterveldt, C.E.M. and Bleecker, E.R. and Bonàs-Guarch, S. and Boomsma, D.I. and Brix, S. and Bunyavanich, S. and Burchard, E.G. and Chen, Z. and Curjuric, I. and Custovic, A. and den Dekker, H.T. and Dharmage, S.C. and Dmitrieva, J. and Duijts, L. and Ege, M.J. and Gauderman, W.J. and Georges, M. and Gieger, C. and Gilliland, F. and Granell, R. and Gui, H. and Hansen, T. and Heinrich, J. and Henderson, J. and Hernandez-Pacheco, N. and Holt, P. and Imboden, M. and Jaddoe, V.W.V. and Jarvelin, M.R. and Jarvis, D.L. and Jensen, K.K. and Jónsdóttir, I. and Kabesch, M. and Kaprio, J. and Kumar, A. and Lee, Y.A. and Levin, A.M. and Li, X. and Lorenzo-Diaz, F. and Melén, E. and Mercader, J.M. and Meyers, D.A. and Myers, R. and Nicolae, D.L. and Nohr, E.A. and Palviainen, T. and Paternoster, L. and Pennell, C.E. and Pershagen, G. and Pino-Yanes, M. and Probst-Hensch, N.M. and Rüschendorf, F. and Simpson, A. and Stefansson, K. and Sunyer, J. and Sveinbjornsson, G. and Thiering, E. and Thompson, P.J. and Torrent, M. and Torrents, D. and Tung, J.Y. and Wang, C.A. and Weidinger, S. and Weiss, S. and Willemsen, G. and Williams, L.K. and Ober, C. and Hinds, D.A. and Ferreira, M.A. and Bisgaard, H. and Strachan, D.P. and Bønnelykke, K.
Nature Genetics 50 (8): 1072-1080. August 2018

Candidate gene testing in clinical cohort studies with multiplexed genotyping and mass spectrometry.
Ashley, S.E. and Meyer, B.A. and Ellis, J.A. and Martino, D.J.
Journal of Visualized Experiments (136): e57601. 21 June 2018

SMARCAD1 haploinsufficiency underlies Huriez syndrome and associated skin cancer susceptibility.
Günther, C. and Lee-Kirsch, M.A. and Eckhard, J. and Matanovic, A. and Kerscher, T. and Rüschendorf, F. and Klein, B. and Berndt, N. and Zimmermann, N. and Flachmeier, C. and Thuß, T. and Lucas, N. and Marenholz, I. and Esparza-Gordillo, J. and Hübner, N. and Traupe, H. and Delaporte, E. and Lee, Y.A.
Journal of Investigative Dermatology 138 (6): 1428-1431. June 2018

Allergy and atopy from infancy to adulthood: messages from the German birth cohort MAS.
Lau, S. and Matricardi, P.M. and Wahn, U. and Lee, Y.A. and Keil, T.
Annals of Allergy Asthma & Immunology 25 May 2018 (In Press)

Eleven loci with new reproducible genetic associations with allergic disease risk.
Ferreira, M.A. and Vonk, J.M. and Baurecht, H. and Marenholz, I. and Tian, C. and Hoffman, J.D. and Helmer, Q. and Tillander, A. and Ullemar, V. and Lu, Y. and Rüschendorf, F. and Hinds, D.A. and Hübner, N. and Weidinger, S. and Magnusson, P.K. and Jorgenson, E. and Lee, Y.A. and Boomsma, D.I. and Karlsson, R. and Almqvist, C. and Koppelman, G.H. and Paternoster, L.
Journal of Allergy and Clinical Immunology 19 April 2018 (In Press)

A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma.
Asai, Y. and Eslami, A. and van Ginkel, C.D. and Akhabir, L. and Wan, M. and Yin, D. and Ellis, G. and Ben-Shoshan, M. and Marenholz, I. and Martino, D. and Ferreira, M.A. and Allen, K. and Mazer, B. and de Groot, H. and de Jong, N.W. and Gerth van Wijk, R. and Dubois, A.E.J. and Grosche, S. and Ashley, S. and Rüschendorf, F. and Kalb, B. and Beyer, K. and Nöthen, M.M. and Lee, Y.A. and Chin, R. and Cheuk, S. and Hoffman, J. and Jorgensen, E. and Witte, J.S. and Melles, R.B. and Hong, X. and Wang, X. and Hui, J. and Musk, A.W.B. and Hunter, M. and James, A.L. and Koppelman, G.H. and Sandford, A.J. and Clarke, A.E. and Daley, D.
Journal of Allergy and Clinical Immunology 141 (4): 1513-1516. April 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
Demenais, F. and Margaritte-Jeannin, P. and Barnes, K.C. and Cookson, W.O.C. and Altmueller, J. and Ang, W. and Barr, R.G. and Beaty, T.H. and Becker, A.B. and Beilby, J. and Bisgaard, H. and Bjornsdottir, U.S. and Bleecker, E. and Bonnelykke, K. and Boomsma, D.I. and Bouzigon, E. and Brightling, C.E. and Brossard, M. and Brusselle, G.G. and Burchard, E. and Burkart, K.M. and Bush, A. and Chan-Yeung, M. and Chung, K.F. and Couto Alves, A. and Curtin, J.A. and Custovic, A. and Daley, D. and de Jongste, J.C. and Del-Rio-Navarro, B.E. and Donohue, K.M. and Duijts, L. and Eng, C. and Eriksson, J.G. and Farrall, M. and Fedorova, Y. and Feenstra, B. and Ferreira, M.A. and Freidin, M.B. and Gajdos, Z. and Gauderman, J. and Gehring, U. and Geller, F. and Genuneit, J. and Gharib, S.A and Gilliland, F. and Granell, R. and Graves, P.E. and Gudbjartsson, D.F. and Haahtela, T. and Heckbert, S.R. and Heederik, D. and Heinrich, J. and Helioevaara, M. and Henderson, J. and Himes, B.E. and Hirose, H. and Hirschhorn, J.N. and Hofman, A. and Holt, P. and Hottenga, J. and Hudson, T.J. and Hui, J. and Imboden, M. and Ivanov, V. and Jaddoe, V.W.V. and James, A. and Janson, C. and Jarvelin, M.R. and Jarvis, D. and Jones, G. and Jonsdottir, I. and Jousilahti, P. and Kabesch, M. and Kähönen, M. and Kantor, D.B. and Karunas, A.S. and Khusnutdinova, E. and Koppelman, G.H. and Kozyrskyj, A.L. and Kreiner, E. and Kubo, M. and Kumar, R. and Kumar, A. and Kuokkanen, M. and Lahousse, L. and Laitinen, T. and Laprise, C. and Lathrop, M. and Lau, S. and Lee, Y.A. and Lehtimaeki, T. and Letort, S. and Levin, A.M. and Li, G. and Liang, L. and Loehr, L.R. and London, S.J. and Loth, D.W. and Manichaikul, A. and Marenholz, I. and Martinez, F.J. and Matheson, M.C. and Mathias, R.A. and Matsumoto, K. and Mbarek, H. and McArdle, W.L. and Melbye, M. and Melen, E. and Meyers, D. and Michel, S. and Mohamdi, H. and Musk, A.W. and Myers, R.A. and Nieuwenhuis, M.A.E. and Noguchi, E. and O'Connor, G.T. and Ogorodova, L.M. and Palmer, C.D. and Palotie, A. and Park, J.E. and Pennell, C.E. and Pershagen, G. and Polonikov, A. and Postma, D.S. and Probst-Hensch, N. and Puzyrev, V.P. and Raby, B.A. and Raitakari, O.T. and Ramasamy, A. and Rich, S.S. and Robertson, C.F. and Romieu, I. and Salam, M.T. and Salomaa, V. and Schluenssen, V. and Scott, R. and Selivanova, P.A. and Sigsgaard, T. and Simpson, A. and Siroux, V. and Smith, L.J. and Solodilova, M. and Standl, M. and Stefansson, K. and Strachan, D.P. and Stricker, B.H. and Takahashi, A. and Thompson, P.J. and Thorleifsson, G. and Thorsteinsdottir, U. and Tiesler, C.M.T. and Torgerson, D.G. and Tsunoda, T. and Uitterlinden, A.G. and van der Valk, R.J.P. and Vaysse, A. and Vedantam, S. and von Berg, A. and von Mutius, E. and Vonk, J.M. and Waage, J. and Wareham, N.J. and Weiss, S.T. and White, W.B. and Wickman, M. and Widén, E. and Willemsen, G. and Williams, L.K. and Wouters, I.M. and Yang, J.J. and Zhao, J.H. and Moffatt, M.F. and Ober, C. and Nicolae, D.L.
Nature Genetics 50 (1): 42-53. January 2018

2017

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.
Ferreira, M.A. and Vonk, J.M. and Baurecht, H. and Marenholz, I. and Tian, C. and Hoffman, J.D. and Helmer, Q. and Tillander, A. and Ullemar, V. and van Dongen, J. and Lu, Yi and Rueschendorf, F. and Esparza-Gordillo, J. and Medway, C.W. and Mountjoy, E. and Burrows, K. and Hummel, O. and Grosche, S. and Brumpton, B.M. and Witte, J.S. and Hottenga, J.J. and Willemsen, G. and Zheng, J. and Rodriguez, E. and Hotze, M. and Franke, A. and Revez, J.A. and Beesley, J. and Matheson, M.C. and Dharmage, S.C. and Bain, L.M. and Fritsche, L.G. and Gabrielsen, M.E. and Balliu, B. and Nielsen, J.B. and Zhou, W. and Hveem, K. and Langhammer, A. and Holmen, O.L. and Løset, M. and Abecasis, G.R. and Willer, C.J. and Arnold, A. and Homuth, G. and Schmidt, C.O. and Thompson, P.J. and Martin, N.G. and Duffy, D.L. and Novak, N. and Schulz, H. and Karrasch, S. and Gieger, C. and Strauch, K. and Melles, R.B. and Hinds, D.A. and Hübner, N. and Weidinger, S. and Magnusson, P.K.E. and Jansen, R. and Jorgenson, E. and Lee, Y.A. and Boomsma, D.I. and Almqvist, C. and Karlsson, R. and Koppelman, G.H. and Paternoster, L.
Nature Genetics 49 (12): 1752-1757. December 2017

Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.
Marenholz, I. and Grosche, S. and Kalb, B. and Rüschendorf, F. and Blümchen, K. and Schlags, R. and Harandi, N. and Price, M. and Hansen, G. and Seidenberg, J. and Röblitz, H. and Yürek, S. and Tschirner, S. and Hong, X. and Wang, X. and Homuth, G. and Schmidt, C.O. and Nöthen, M.M. and Hübner, N. and Niggemann, B. and Beyer, K. and Lee, Y.A.
Nature Communications 8 (1): 1056. 20 October 2017

Genetic variation in the ADIPOQ gene, adiponectin concentrations and risk of colorectal cancer: a Mendelian Randomization analysis using data from three large cohort studies.
Nimptsch, K. and Song, M. and Aleksandrova, K. and Katsoulis, M. and Freisling, H. and Jenab, M. and Gunter, M.J. and Tsilidis, K.K. and Weiderpass, E. and Bueno-De-Mesquita, H.B. and Chong, D.Q. and Jensen, M.K. and Wu, C. and Overvad, K. and Kühn, T. and Barrdahl, M. and Melander, O. and Jirstrom, K. and Peeters, P.H. and Sieri, S. and Panico, S. and Cross, A.J. and Riboli, E. and Van Guelpen, B. and Myte, R. and Huerta, J.M. and Rodriguez-Barranco, M. and Quirós, J.R. and Dorronsoro, M. and Tjønneland, A. and Olsen, A. and Travis, R. and Boutron-Ruault, M.C. and Carbonnel, F. and Severi, G. and Bonet, C. and Palli, D. and Janke, J. and Lee, Y.A. and Boeing, H. and Giovannucci, E.L. and Ogino, S. and Fuchs, C.S. and Rimm, E. and Wu, K. and Chan, A.T. and Pischon, T.
European Journal of Epidemiology 32 (5): 419-430. May 2017

Genomewide association study of peanut allergy reproduces association with amino acid polymorphisms in HLA-DRB1.
Martino, D.J. and Ashley, S. and Koplin, J. and Ellis, J. and Saffery, R. and Dharmage, S.C. and Gurrin, L. and Matheson, M.C. and Kalb, B. and Marenholz, I. and Beyer, K. and Lee, Y.A. and Hong, X. and Wang, X. and Vukevic, D. and Motyer, A. and Leslie, S. and Allen, K.J. and Ferreira, M.A.R.
Clinical and Experimental Allergy 47 (2): 217-223. February 2017

2016

DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis.
Sarnowski, C. and Laprise, C. and Malerba, G. and Moffatt, M.F. and Dizier, M.H. and Morin, A. and Vincent, Q.B. and Rohde, K. and Esparza-Gordillo, J. and Margaritte-Jeannin, P. and Liang, L. and Lee, Y.A. and Bousquet, J. and Siroux, V. and Pignatti, P.F. and Cookson, W.O. and Lathrop, M. and Pastinen, T. and Demenais, F. and Bouzigon, E.
Journal of Allergy and Clinical Immunology 138 (3): 748-753. September 2016

Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes.
Schmitt, J. and Schwarz, K. and Baurecht, H. and Hotze, M. and Fölster-Holst, R. and Rodríguez, E. and Lee, Y.A.E. and Franke, A. and Degenhardt, F. and Lieb, W. and Gieger, C. and Kabesch, M. and Nöthen, M.M. and Irvine, A.D. and McLean, W.H.I. and Deckert, S. and Stephan, V. and Schwarz, P. and Aringer, M. and Novak, N. and Weidinger, S.
Journal of Allergy and Clinical Immunology 137 (1): 130-136. January 2016

2015

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Paternoster, L. and Standl, M. and Waage, J. and Baurecht, H. and Hotze, M. and Strachan, D.P. and Curtin, J.A. and Bønnelykke, K. and Tian, C. and Takahashi, A. and Esparza-Gordillo, J. and Alves, A.C. and Thyssen, J.P. and den Dekker, H.T. and Ferreira, M.A. and Altmaier, E. and Sleiman, P.M.A. and Xiao, F.L. and Gonzalez, J.R. and Marenholz, I. and Kalb, B. and Pino-Yanes, M. and Xu, C.J. and Carstensen, L. and Groen-Blokhuis, M.M. and Venturini, C. and Pennell, C.E. and Barton, S.J. and Levin, A.M. and Curjuric, I. and Bustamante, M. and Kreiner-Møller, E. and Lockett, G.A. and Bacelis, J. and Bunyavanich, S. and Myers, R.A. and Matanovic, A. and Kumar, A. and Tung, J.Y. and Hirota, T. and Kubo, M. and McArdle, W.L. and Henderson, A.J. and Kemp, J.P. and Zheng, J. and Smith, G.D. and Rüschendorf, F. and Bauerfeind, A. and Lee-Kirsch, M.A. and Arnold, A. and Homuth, G. and Schmidt, C.O. and Mangold, E. and Cichon, S. and Keil, T. and Rodríguez, E. and Peters, A. and Franke, A. and Lieb, W. and Novak, N. and Fölster-Holst, R. and Horikoshi, M. and Pekkanen, J. and Sebert, S. and Husemoen, L.L. and Grarup, N. and de Jongste, J.C. and Rivadeneira, F. and Hofman, A. and Jaddoe, V.W.V. and Pasmans, S.G.M.A. and Elbert, N.J. and Uitterlinden, A.G. and Marks, G.B. and Thompson, P.J. and Matheson, M.C. and Robertson, C.F. and Ried, J.S. and Li, J. and Zuo, X.B. and Zheng, X.D. and Yin, X.Y. and Sun, L.D. and McAleer, M.A. and O'Regan, G.M. and Fahy, C.M.R. and Campbell, L.E. and Macek, M. and Kurek, M. and Hu, D. and Eng, C. and Postma, D.S. and Feenstra, B. and Geller, F. and Hottenga, J.J. and Middeldorp, C.M. and Hysi, P. and Bataille, V. and Spector, T. and Tiesler, C.M.T. and Thiering, E. and Pahukasahasram, B. and Yang, J.J. and Imboden, M. and Huntsman, S. and Vilor-Tejedor, N. and Relton, C.L. and Myhre, R. and Nystad, W. and Custovic, A. and Weiss, S.T. and Meyers, D.A. and Söderhäll, C. and Melén, E. and Ober, C. and Raby, B.A. and Simpson, A. and Jacobsson, B. and Holloway, J.W. and Bisgaard, H. and Sunyer, J. and Probst-Hensch, N.M. and Williams, L.K. and Godfrey, K.M. and Wang, C.A. and Boomsma, D.I. and Melbye, M. and Koppelman, G.H. and Jarvis, D. and McLean, W.H.I. and Irvine, A.D. and Zhang, X.J. and Hakonarson, H. and Gieger, C. and Burchard, E.G. and Martin, N.G. and Duijts, L. and Linneberg, A. and Jarvelin, M.R. and Noethen, M.M. and Lau, S. and Hübner, N. and Lee, Y.A. and Tamari, M. and Hinds, D.A. and Glass, D. and Brown, S.J. and Heinrich, J. and Evans, D.M. and Weidinger, S.
Nature Genetics 47 (12): 1449-1456. December 2015

Meta-analysis identifies seven susceptibility loci involved in the atopic march.
Marenholz, I. and Esparza-Gordillo, J. and Rüschendorf, F. and Bauerfeind, A. and Strachan, D.P. and Spycher, B.D. and Baurecht, H. and Margaritte-Jeannin, P. and Sääf, A. and Kerkhof, M. and Ege, M. and Baltic, S. and Matheson, M.C. and Li, J. and Michel, S. and Ang, W.Q. and McArdle, W. and Arnold, A. and Homuth, G. and Demenais, F. and Bouzigon, E. and Söderhäll, C. and Pershagen, G. and de Jongste, J.C. and Postma, D.S. and Braun-Fahrlaender, C. and Horak, E. and Ogorodova, L.M. and Puzyrev, V.P. and Bragina, E.Y. and Hudson, T.J. and Morin, C. and Duffy, D.L. and Marks, G.B. and Robertson, C.F. and Montgomery, G.W. and Musk, B. and Thompson, P.J. and Martin, N.G. and James, A. and Sleiman, P. and Toskala, E. and Rodriguez, E. and Fölster-Holst, R. and Franke, A. and Lieb, W. and Gieger, C. and Heinzmann, A. and Rietschel, E. and Keil, T. and Cichon, S. and Nöthen, M.M. and Pennell, C.E. and Sly, P.D. and Schmidt, C.O. and Matanovic, A. and Schneider, V. and Heinig, M. and Hübner, N. and Holt, P.G. and Lau, S. and Kabesch, M. and Weidinger, S. and Hakonarson, H. and Ferreira, M.A.R. and Laprise, C. and Freidin, M.B. and Genuneit, J. and Koppelman, G.H. and Melén, E. and Dizier, M.H. and Henderson, A.J. and Lee, Y.A.
Nature Communications 6 : 8804. 6 November 2015

Prediction and prevention of allergic rhinitis: A birth cohort study of 20 years.
Grabenhenrich, L.B. and Keil, T. and Reich, A. and Gough, H. and Beschorner, J. and Hoffmann, U. and Bauer, C.P. and Forster, J. and Schuster, A. and Schramm, D. and Nitsche, O. and Zepp, F. and Lee, Y.A. and Bergmann, R. and Bergmann, K. and Wahn, U. and Lau, S.
Journal of Allergy and Clinical Immunology 136 (4): 932-940. October 2015

The genetics of the skin barrier in eczema and other allergic disorders.
Marenholz, I. and Esparza-Gordillo, J. and Lee, Y.A.
Current Opinion in Allergy and Clinical Immunology 15 (5): 426-434. October 2015

A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis.
Schaarschmidt, H. and Ellinghaus, D. and Rodríguez, E. and Kretschmer, A. and Baurecht, H. and Lipinski, S. and Meyer-Hoffert, U. and Harder, J. and Lieb, W. and Novak, N. and Fölster-Holst, R. and Esparza-Gordillo, J. and Marenholz, I. and Ruschendorf, F. and Hubner, N. and Reischl, E. and Waldenberger, M. and Gieger, C. and Illig, T. and Kabesch, M. and Zhang, X.J. and Xiao, F.L. and Lee, Y.A. and Franke, A. and Weidinger, S.
Journal of Allergy and Clinical Immunology 136 (3): 802-806. September 2015

Plasma fetuin-A concentration, genetic variation in the AHSG gene and risk of colorectal cancer.
Nimptsch, K. and Aleksandrova, K. and Boeing, H. and Janke, J. and Lee, Y.A. and Jenab, M. and Yeon Kong, S. and Tsilidis, K.K. and Weiderpass, E. and Bueno-De-Mesquita, B.H. and Siersema, P.D. and Jansen, E.H.J.M. and Trichopoulou, A. and Tjønneland, A. and Olsen, A. and Wu, C. and Overvad, K. and Boutron-Ruault, M.C. and Racine, A. and Freisling, H. and Katzke, V. and Kaaks, R. and Lagiou, P. and Trichopoulos, D. and Severi, G. and Naccarati, A. and Mattiello, A. and Palli, D. and Grioni, S. and Tumino, R. and Peeters, P.H. and Ljuslinder, I. and Nyström, H. and Brändstedt, J. and Sánchez, M.J. and Barricarte Gurrea, A. and Bonet Bonet, C. and Chirlaque, M.D. and Dorronsoro, M. and Quirós, J.R. and Travis, R.C. and Khaw, K.T. and Wareham, N. and Riboli, E. and Gunter, M.J. and Pischon, T.
International Journal of Cancer 137 (4): 911-920. 15 August 2015

Allergic multimorbidity of asthma, rhinitis, and eczema over 20 years in the German birth cohort MAS.
Gough, H. and Grabenhenrich, L. and Reich, A. and Eckers, N. and Nitsche, O. and Schramm, D. and Beschorner, J. and Hoffmann, U. and Schuster, A. and Bauer, C.P. and Forster, J. and Zepp, F. and Lee, Y.A. and Bergmann, R.L. and Bergmann, K.E. and Wahn, U. and Lau, S. and Keil, T.
Pediatric Allergy and Immunology 26 (5): 431-437. August 2015

eQTL mapping identifies insertion- and deletion-specific eQTLs in multiple tissues.
Huang, J. and Chen, J. and Esparza, J. and Ding, J. and Elder, J.T. and Abecasis, G.R. and Lee, Y.A. and Lathrop, G.M. and Moffatt, M.F. and Cookson, W.O.C. and Liang, L.
Nature Communications 6 : 6821. 8 May 2015

Maternal filaggrin mutations increase the risk of atopic dermatitis in children: an effect independent of mutation inheritance.
Esparza-Gordillo, J. and Matanovic, A. and Marenholz, I. and Bauerfeind, A. and Rohde, K. and Nemat, K. and Lee-Kirsch, M.A. and Nordenskjöld, M. and Winge, M.C.G. and Keil, T. and Krüger, R. and Lau, S. and Beyer, K. and Kalb, B. and Niggemann, B. and Hübner, N. and Cordell, H.J. and Bradley, M. and Lee, Y.A.
PLoS Genetics 11 (3): e1005076. 10 March 2015

Association of CRP genetic variants with blood concentrations of C-reactive protein and colorectal cancer risk.
Nimptsch, K. and Aleksandrova, K. and Boeing, H. and Janke, J. and Lee, Y.A. and Jenab, M. and Bueno-De-Mesquita, B.H. and Jansen, E.H.J.M. and Tsilidis, K.K. and Trichopoulou, A. and Weiderpass, E. and Wu, C. and Overvad, K. and Tjønneland, A. and Boutron-Ruault, M.C. and Dossus, L. and Racine, A. and Kaaks, R. and Canzian, F. and Lagiou, P. and Trichopoulos, D. and Palli, D. and Agnoli, C. and Tumino, R. and Vineis, P. and Panico, S. and Johansson, A. and VanGuelpen, B. and Khaw, K.T. and Wareham, N. and Peeters, P.H. and Quirós, J.R. and Venceslá García, A. and Molina-Montes, E. and Dorronsoro, M. and Chirlaque, M.D. and Gurrea, A.B. and Key, T.J. and Duarte-Salles, T. and Stepien, M. and Gunter, M.J. and Riboli, E. and Pischon, T.
International Journal of Cancer 136 (5): 1181-1192. 1 March 2015

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.
Baurecht, H. and Hotze, M. and Brand, S. and Büning, C. and Cormican, P. and Corvin, A. and Ellinghaus, D. and Ellinghaus, E. and Esparza-Gordillo, J. and Fölster-Holst, R. and Franke, A. and Gieger, C. and Hubner, N. and Illig, T. and Irvine, A.D. and Kabesch, M. and Lee, Y.A.E. and Lieb, W. and Marenholz, I. and McLean, W.H.I. and Morris, D.W. and Mrowietz, U. and Nair, R. and Nöthen, M.M. and Novak, N. and O'Regan, G.M. and Schreiber, S. and Smith, C. and Strauch, K. and Stuart, P.E. and Trembath, R. and Tsoi, L.C. and Weichenthal, M. and Barker, J. and Elder, J.T. and Weidinger, S. and Cordell, H.J. and Brown, S.J.
American Journal of Human Genetics 96 (1): 104-120. 8 January 2015

Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.
Günther, C. and Kind, B. and Reijns, M.A.M. and Berndt, N. and Martinez-Bueno, M. and Wolf, C. and Tüngler, V. and Chara, O. and Lee, Y.A. and Hübner, N. and Bicknell, L. and Blum, S. and Krug, C. and Schmidt, F. and Kretschmer, S. and Koss, S. and Astell, K.R. and Ramantani, G. and Bauerfeind, A. and Morris, D.L. and Cunninghame Graham, D.S. and Bubeck, D. and Leitch, A. and Ralston, S.H. and Blackburn, E.A. and Gahr, M. and Witte, T. and Vyse, T.J. and Melchers, I. and Mangold, E. and Nöthen, M.M. and Aringer, M. and Kuhn, A. and Lüthke, K. and Unger, L. and Bley, A. and Lorenzi, A. and Isaacs, J.D. and Alexopoulou, D. and Conrad, K. and Dahl, A. and Roers, A. and Alarcon-Riquelme, M.E. and Jackson, A.P. and Lee-Kirsch, M.A.
Journal of Clinical Investigation 125 (1): 413-424. 2 January 2015

2014

Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure.
Scholtens, S. and Postma, D.S. and Moffatt, M.F. and Panasevich, S. and Granell, R. and Henderson, A.J. and Melen, E. and Nyberg, F. and Pershagen, G. and Jarvis, D. and Ramasamy, A. and Wjst, M. and Svanes, C. and Bouzigon, E. and Demenais, F. and Kauffmann, F. and Siroux, V. and von Mutius, E. and Ege, M.J. and Braun-Fahrlaender, C. and Genuneit, J. and Brunekreef, B. and Smit, H.A. and Wijga, A.H. and Kerkhof, M. and Curjuric, I. and Imboden, M. and Thun, G.A. and Probst-Hensch, N. and Freidin, M.B. and Bragina, E.I. and Deev, I.A. and Puzyrev, V.P. and Daley, D. and Park, J. and Becker, A. and Chan-Yeung, M. and Kozyrskyj, A.L. and Pare, P. and Marenholz, I. and Lau, S. and Keil, T. and Lee, Y.A. and Kabesch, M. and Wijmenga, C. and Franke, L. and Nolte, I.M. and Vonk, J. and Kumar, A. and Farrall, M. and Cookson, W.O.C.M. and Strachan, D.P. and Koppelman, G.H. and Boezen, H.M.
Journal of Allergy and Clinical Immunology 133 (3): 885-888. March 2014

2013

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.
Saunders, S.P. and Goh, C.S.M. and Brown, S.J. and Palmer, C.N.A. and Porter, R.M. and Cole, C. and Campbell, L.E. and Gierlinski, M. and Barton, G.J. and Schneider, G. and Balmain, A. and Prescott, A.R. and Weidinger, S. and Baurecht, H. and Kabesch, M. and Gieger, C. and Lee, Y.A. and Tavendale, R. and Mukhopadhyay, S. and Turner, S.W. and Madhok, V.B. and Sullivan, F.M. and Relton, C. and Burn, J. and Meggitt, S. and Smith, C.H. and Allen, M.A. and Barker, J.N.W.N. and Reynolds, N.J. and Cordell, H.J. and Irvine, A.D. and McLean, W.H.I. and Sandilands, A. and Fallon, P.G.
Journal of Allergy and Clinical Immunology 132 (5): 1121-1129. November 2013

Shared genetic determinants between eczema and other immune-related diseases.
Marenholz, I. and Esparza-Gordillo, J. and Lee, Y.A.
Current Opinion in Allergy and Clinical Immunology 13 (5): 478-486. October 2013

A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis.
Esparza-Gordillo, J. and Schaarschmidt, H. and Liang, L. and Cookson, W. and Bauerfeind, A. and Lee-Kirsch, M.A. and Nemat, K. and Henderson, J. and Paternoster, L. and Harper, J.L. and Mangold, E. and Nothen, M.M. and Rüschendorf, F. and Kerscher, T. and Marenholz, I. and Matanovic, A. and Lau, S. and Keil, T. and Bauer, C.P. and Kurek, M. and Ciechanowicz, A. and Macek, M. and Franke, A. and Kabesch, M. and Hubner, N. and Abecasis, G. and Weidinger, S. and Moffatt, M. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 132 (2): 371-377. August 2013

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.
Baud, A. and Hermsen, R. and Guryev, V. and Stridh, P. and Graham, D. and McBride, M.W. and Foroud, T. and Calderari, S. and Diez, M. and Ockinger, J. and Beyeen, A.D. and Gillett, A. and Abdelmagid, N. and Guerreiro-Cacais, A.O. and Jagodic, M. and Tuncel, J. and Norin, U. and Beattie, E. and Huynh, N. and Miller, W.H. and Koller, D.L. and Alam, I. and Falak, S. and Osborne-Pellegrin, M. and Martinez-Membrives, E. and Canete, T. and Blazquez, G. and Vicens-Costa, E. and Mont-Cardona, C. and Diaz-Moran, S. and Tobena, A. and Hummel, O. and Zelenika, D. and Saar, K. and Patone, G. and Bauerfeind, A. and Bihoreau, M.T. and Heinig, M. and Lee, Y.A. and Rintisch, C. and Schulz, H. and Wheeler, D.A. and Worley, K.C. and Muzny, D.M. and Gibbs, R.A. and Lathrop, M. and Lansu, N. and Toonen, P. and Ruzius, F.P. and de Bruijn, E. and Hauser, H. and Adams, D.J. and Keane, T. and Atanur, S.S. and Aitman, T.J. and Flicek, P. and Malinauskas, T. and Jones, E.Y. and Ekman, D. and Lopez-Aumatell, R. and Dominiczak, A.F. and Johannesson, M. and Holmdahl, R. and Olsson, T. and Gauguier, D. and Hubner, N. and Fernandez-Teruel, A. and Cuppen, E. and Mott, R. and Flint, J.
Nature Genetics 45 (7): 767-775. July 2013

High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.
Ellinghaus, D. and Baurecht, H. and Esparza-Gordillo, J. and Rodríguez, E. and Matanovic, A. and Marenholz, I. and Hübner, N. and Schaarschmidt, H. and Novak, N. and Michel, S. and Maintz, L. and Werfel, T. and Meyer-Hoffert, U. and Hotze, M. and Prokisch, H. and Heim, K. and Herder, C. and Hirota, T. and Tamari, M. and Kubo, M. and Takahashi, A. and Nakamura, Y. and Tsoi, L.C. and Stuart, P. and Elder, J.T. and Sun, L. and Zuo, X. and Yang, S. and Zhang, X. and Hoffmann, P. and Nöthen, M.M. and Fölster-Holst, R. and Winkelmann, J. and Illig, T. and Boehm, B.O. and Duerr, R.H. and Büning, C. and Brandt, S. and Glas, J. and McAleer, M.A. and Fahy, C.M. and Kabesch, M. and Brown, S. and McLean, W.H.I. and Irvine, A.D. and Schreiber, S. and Lee, Y.A. and Franke, A. and Weidinger, S.
Nature Genetics 45 (7): 808-812. July 2013

Genome-wide association study of body mass index in 23 000 individuals with and without asthma.
Melén, E. and Granell, R. and Kogevinas, M. and Strachan, D. and Gonzalez, J.R. and Wjst, M. and Jarvis, D. and Ege, M. and Braun-Fahrländer, C. and Genuneit, J. and Horak, E. and Bouzigon, E. and Demenais, F. and Kauffmann, F. and Siroux, V. and Michel, S. and von Berg, A. and Heinzmann, A. and Kabesch, M. and Probst-Hensch, N.M. and Curjuric, I. and Imboden, M. and Rochat, T. and Henderson, J. and Sterne, J.A.C. and McArdle, W.L. and Hui, J. and James, A.L. and William Musk, A. and Palmer, L.J. and Becker, A. and Kozyrskyj, A.L. and Chan-Young, M. and Park, J.E. and Leung, A. and Daley, D. and Freidin, M.B. and Deev, I.A. and Ogorodova, L.M. and Puzyrev, V.P. and Celedón, J.C. and Brehm, J.M. and Cloutier, M.M. and Canino, G. and Acosta-Pérez, E. and Soto-Quiros, M. and Avila, L. and Bergstroem, A. and Magnusson, J. and Söderhäll, C. and Kull, I. and Scholtens, S. and Marike Boezen, H. and Koppelman, G.H. and Wijga, A.H. and Marenholz, I. and Esparza-Gordillo, J. and Lau, S. and Lee, Y.A. and Standl, M. and Tiesler, C.M. and Flexeder, C. and Heinrich, J. and Myers, R.A. and Ober, C. and Nicolae, D.L. and Farrall, M. and Kumar, A. and Moffatt, M.F. and Cookson, W.O. and Lasky-Su, J.
Clinical and Experimental Allergy 43 (4): 463-474. April 2013

2012

The ANO3/MUC15 locus is associated with eczema in families ascertained through asthma.
Dizier, M.H. and Margaritte-Jeannin, P. and Madore, A.M. and Esparza-Gordillo, J. and Moffatt, M.F. and Corda, E. and Monier, F. and Guilloud-Bataille, M. and Franke, A. and Weidinger, S. and Annesi-Maesano, I. and Just, J. and Pin, I. and Kauffmann, F. and Cookson, W. and Lee, Y.A. and Laprise, C. and Lathrop, M. and Bouzigon, E. and Demenais, F.
Journal of Allergy and Clinical Immunology 129 (6): 1547-1553. June 2012

An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity.
Kuehnen, P. and Mischke, M. and Wiegand, S. and Sers, C. and Horsthemke, B. and Lau, S. and Keil, T. and Lee, Y.A. and Grueters, A. and Krude, H.
PLoS Genetics 8 (3): e1002543. 15 March 2012

Multi-locus stepwise regression: a haplotype-based algorithm for finding genetic associations applied to atopic dermatitis.
Knuppel, S. and Esparza-Gordillo, J. and Marenholz, I. and Holzhutter, H. and Bauerfeind, A. and Ruether, A. and Weidinger, S. and Lee, Y.A. and Rohde, K.
BMC Medical Genetics 13 (1): 8. 27 January 2012

2011

Association screening in the epidermal differentiation complex (EDC) identifies an SPRR3 repeat number variant as a risk factor for eczema.
Marenholz, I. and Rivera, V.A. and Esparza-Gordillo, J. and Bauerfeind, A. and Lee-Kirsch, M.A. and Ciechanowicz, A. and Kurek, M. and Piskackova, T. and Macek, M. and Lee, Y.A.
Journal of Investigative Dermatology 131 (8): 1644-1649. August 2011

The eczema risk variant on chromosome 11q13 (rs7927894) in the population-based ALSPAC cohort: a novel susceptibility factor for asthma and hay fever.
Marenholz, I. and Bauerfeind, A. and Esparza-Gordillo, J. and Kerscher, T. and Granell, R. and Nickel, R. and Lau, S. and Henderson, J. and Lee, Y.A.
Human Molecular Genetics 20 (12): 2443-2449. 15 June 2011

2010

Genome-wide approaches to the etiology of eczema.
Esparza-Gordillo, J. and Marenholz, I. and Lee, Y.A.
Current Opinion in Allergy and Clinical Immunology 10 (5): 418-426. October 2010

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.
Heinig, M. and Petretto, E. and Wallace, C. and Bottolo, L. and Rotival, M. and Lu, H. and Li, Y. and Sarwar, R. and Langley, S.R. and Bauerfeind, A. and Hummel, O. and Lee, Y.A. and Paskas, S. and Rintisch, C. and Saar, K. and Cooper, J. and Buchan, R. and Gray, E.E. and Cyster, J.G. and Braund, P. and Gracey, J. and Krishnan, U. and Moore, J.S. and Nelson, C.P. and Pollard, H. and Attwood, T. and Crisp-Hihn, A. and Foad, N. and Jolley, J. and Lloyd-Jones, H. and Muir, D. and Murray, E. and O'Leary, K. and Rankin, A. and Sambrook, J. and Godfroy, T. and Brocheton, J. and Proust, C. and Schmitz, G. and Heimerl, S. and Lugauer, I. and Belz, S. and Gulde, S. and Linsel-Nitschke, P. and Sager, H. and Schroeder, L. and Lundmark, P. and Syvannen, A.C. and Neudert, J. and Scholz, M. and Deloukas, P. and Gray, E. and Gwilliams, R. and Niblett, D. and Erdmann, J. and Hengstenberg, C. and Maouche, S. and Ouwehand, W.H. and Rice, C.M. and Samani, N.J. and Schunkert, H. and Goodall, A.H. and Schulz, H. and Roider, H.G. and Vingron, M. and Blankenberg, S. and Muenzel, T. and Zeller, T. and Szymczak, S. and Ziegler, A. and Tiret, L. and Smyth, D.J. and Pravenec, M. and Aitman, T.J. and Cambien, F. and Clayton, D. and Todd, J.A. and Huebner, N. and Cook, S.A.
Nature 467 (7314): 460-464. 23 September 2010

2009

Genetik des atopischen Ekzems: Neue Gene und Pathomechanismen [The genetics of atopic eczema: New genes and pathomechanisms].
Marenholz, I. and Lee, Y.A.
Medizinische Genetik 21 (4): 493-497. December 2009

Familial and sporadic 15q13.3 microdeletions in idiopathic generalized epilepsy: precedent for disorders with complex inheritance.
Dibbens, L.M. and Mullen, S. and Helbig, I. and Mefford, H.C. and Bayly, M.A. and Bellows, S. and Leu, C. and Trucks, H. and Obermeier, T. and Wittig, M. and Franke, A. and Caglayan, H. and Yapici, Z. and Sander, T. and Eichler, E.E. and Scheffer, I.E. and Mulley, J.C. and Berkovic, S.F.
Human Molecular Genetics 18 (19): 3626-3631. 1 October 2009

IL13 variants are associated with total serum IgE and early sensitization to food allergens in children with atopic dermatitis.
Zitnik, S.E. and Rueschendorf, F. and Mueller, S. and Sengler, C. and Lee, Y.A. and Griffioen, R.W. and Meglio, P. and Wahn, U. and Witt, H. and Nickel, R.
Pediatric Allergy and Immunology 20 (6): 551-555. September 2009

No association between the eczema genes COL29A1 and IL31 and inflammatory bowel disease.
Zucchelli, M. and Torkvist, L. and Bresso, F. and Halfvarson, J. and Soederhaell, C. and Lee, Y.A. and Loefberg, R. and Kere, J. and D'Amato, M.
Inflammatory Bowel Diseases 15 (7): 961-962. July 2009

Association of filaggrin loss-of-function-mutations with atopic dermatitis and asthma in the early treatment of the atopic child (ETAC) population.
Mueller, S. and Marenholz, I. and Lee, Y.A. and Sengler, C. and Zitnik, S.E. and Griffioen, R.W. and Meglio, P. and Wahn, U. and Nickel, R.
Pediatric Allergy and Immunology 20 (4): 358-361. June 2009

A common variant on chromosome 11q13 is associated with atopic dermatitis.
Esparza-Gordillo, J. and Weidinger, S. and Foelster-Holst, R. and Bauerfeind, A. and Rueschendorf, F. and Patone, G. and Rohde, K. and Marenholz, I. and Schulz, F. and Kerscher, T. and Huebner, N. and Wahn, U. and Schreiber, S. and Franke, A. and Vogler, R. and Heath, S. and Baurecht, H. and Novak, N. and Rodriguez, E. and Illig, T. and Lee-Kirsch, M.A. and Ciechanowicz, A. and Kurek, M. and Piskackova, T. and Macek, M. and Lee, Y.A. and Ruether, A.
Nature Genetics 41 (5): 596-601. May 2009

ICOS-gene variants are not associated with atopic disease susceptibility in European children.
Beier, K.C. and Humberdros, S. and Witt, H. and Illi, S. and Rueschendorf, F. and Nickel, R. and Lee, Y.A. and Lau, S. and Wahn, U. and Hamelmann, E.
Pediatric Allergy and Immunology 20 (3): 242-245. May 2009

An interaction between filaggrin mutations and early food sensitization improves the prediction of childhood asthma.
Marenholz, I. and Kerscher, T. and Bauerfeind, A. and Esparza-Gordillo, J. and Nickel, R. and Keil, T. and Lau, S. and Rohde, K. and Wahn, U. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 123 (4): 911-916. April 2009

2008

SNP and haplotype mapping for genetic analysis in the rat.
Saar, K. and Beck, A. and Bihoreau, M.T. and Birney, E. and Brocklebank, D. and Chen, Y. and Cuppen, E. and Demonchy, S. and Dopazo, J. and Flicek, P. and Foglio, M. and Fujiyama, A. and Gut, I.G. and Gauguier, D. and Guigo, R. and Guryev, V. and Heinig, M. and Hummel, O. and Jahn, N. and Klages, S. and Kren, V. and Kube, M. and Kuhl, H. and Kuramoto, T. and Kuroki, Y. and Lechner, D. and Lee, Y.A. and Lopez-Bigas, N. and Lathrop, G.M. and Mashimo, T. and Medina, I. and Mott, R. and Patone, G. and Perrier-Cornet, J.A. and Platzer, M. and Pravenec, M. and Reinhardt, R. and Sakaki, Y. and Schilhabel, M. and Schulz, H. and Serikawa, T. and Shikhagaie, M. and Tatsumoto, S. and Taudien, S. and Toyoda, A. and Voigt, B. and Zelenika, D. and Zimdahl, H. and Huebner, N.
Nature Genetics 40 (5): 560-566. May 2008

G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth.
Pasternack, S.M. and von Kuegelgen, I. and Aboud, K.A. and Lee, Y.A. and Rueschendorf, F. and Voss, K. and Hillmer, A.M. and Molderings, G.J. and Franz, T. and Ramirez, A. and Nuernberg, P. and Noethen, M.M. and Betz, R.C.
Nature Genetics 40 (3): 329-334. March 2008

2007

A common haplotype of the IL-31 gene influencing gene expression is associated with nonatopic eczema.
Schulz, F. and Marenholz, I. and Foelster-Holst, R. and Chen, C. and Sternjak, A. and Baumgrass, R. and Esparza-Gordillo, J. and Grueber, C. and Nickel, R. and Schreiber, S. and Stoll, M. and Kurek, M. and Rueschendorf, F. and Huebner, N. and Wahn, U. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 120 (5): 1097-1102. November 2007

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.
Lee-Kirsch, M.A. and Gong, M. and Chowdhury, D. and Senenko, L. and Engel, K. and Lee, Y.A. and de Silva, U. and Bailey, S.L. and Witte, T. and Vyse, T.J. and Kere, J. and Pfeiffer, C. and Harvey, S. and Wong, A. and Koskenmies, S. and Hummel, O. and Rohde, K. and Schmidt, R.E. and Dominiczak, A.F. and Gahr, M. and Hollis, T. and Perrino, F.W. and Lieberman, J. and Huebner, N.
Nature Genetics 39 (9): 1065-1067. September 2007

Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis.
Soederhaell, C. and Marenholz, I. and Kerscher, T. and Rueschendorf, F. and Esparza-Gordillo, J. and Worm, M. and Gruber, C. and Mayr, G. and Albrecht, M. and Rohde, K. and Schulz, H. and Wahn, U. and Huebner, N. and Lee, Y.A.
PLoS Biology 5 (9): e242. September 2007

2006

S100A1-deficient male mice exhibit increased exploratory activity and reduced anxiety-related responses.
Ackermann, G.E. and Marenholz, I. and Wolfer, D.P. and Chan, W.Y. and Schaefer, B. and Erne, P. and Heizmann, C.W.
Biochimica et Biophysica Acta - Molecular Cell Research 1763 (11): 1307-1319. November 2006

Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.
Marenholz, I. and Nickel, R. and Rueschendorf, F. and Schulz, F. and Esparza-Gordillo, J. and Kerscher, T. and Grueber, C. and Lau, S. and Worm, M. and Keil, T. and Kurek, M. and Zaluga, E. and Wahn, U. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 118 (4): 866-871. October 2006

Susceptibility loci for atopic dermatitis on chromosome 21 in a Swedish population.
Bu, L.M. and Bradley, M. and Soederhaell, C. and Wahlgren, C.F. and Kockum, I. and Nordenskjoeld, M.
Allergy 61 (5): 617-621. May 2006

Genome-wide linkage analysis of allergic rhinoconjunctivitis in a Swedish population.
Bu, L.M. and Bradley, M. and Soederhaell, C. and Wahlgren, C.F. and Kockum, I. and Nordenskjoeld, M.
Clinical and Experimental Allergy 36 (2): 204-210. February 2006

2005

Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24.
Schumacher, J. and Kaneva, R. and Jamra, R.A. and Diaz, G.O. and Ohlraun, S. and Milanova, V. and Lee, Y.A. and Rivas, F. and Mayoral, F. and Fuerst, R. and Flaquer, A. and Windemuth, C. and Gay, E. and Sanz, S. and Gonzalez, M.J. and Gil, S. and Cabaleiro, F. and del Rio, F. and Perez, F. and Haro, J. and Kostov, C. and Chorbov, V. and Nikolova-Hill, A. and Stoyanova, V. and Onchev, G. and Kremensky, I. and Strauch, K. and Schulze, T.G. and Nuernberg, P. and Gaebel, W. and Klimke, A. and Auburger, G. and Wienker, T.F. and Kalaydjieva, L. and Propping, P. and Cichon, S. and Jablensky, A. and Rietschel, M. and Noethen, M.M.
American Journal of Human Genetics 77 (6): 1102-1111. 1 December 2005

Phenotypic and genetic heterogeneity in a genome-wide linkage study of asthma families.
Altmueller, J. and Seidel, C. and Lee, Y.A. and Loesgen, S. and Bulle, D. and Friedrichs, F. and Jellouschek, H. and Kelber, J. and Keller, A. and Schuster, A. and Silbermann, M. and Wahlen, W. and Wolff, P. and Rueschendorf, F. and Schlenvoigt, G. and Nuernberg, P. and Wjst, M.
BMC Pulmonary Medicine 5 : 1. 5 January 2005

Lack of association of the G protein-coupled receptor for asthma susceptibility gene with atopic dermatitis.
Soederhaell, C. and Marenholz, I. and Nickel, R. and Grueber, C. and Kehrt, R. and Rohde, K. and Griffioen, R.W. and Meglio, P. and Tarani, L. and Gustafsson, D. and Hoffmann, U. and Gerstner, B. and Mueller, S. and Wahn, U. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 116 (1): 220-221. 1 January 2005

2004

A SNP map of the rat genome generated from cDNA sequences.
Zimdahl, H. and Nyakatura, G. and Brandt, P. and Schulz, H. and Hummel, O. and Fartmann, B. and Brett, D. and Droege, M. and Monti, J. and Lee, Y.A. and Sun, Y.Y. and Zhao, S.Y. and Winter, E.E. and Ponting, C.P. and Chen, Y. and Kasprzyk, A. and Birney, E. and Ganten, D. and Huebner, N.
Science 303 (5659): 807-807. 1 January 2004

2003

Genome-wide linkage reveals a locus for human essential (primary) hypertension on chromosome 12p.
Gong, M. and Zhang, H.Y. and Schulz, H. and Lee, Y.A. and Sun, K. and Baehring, S. and Luft, F.C. and Nuernberg, P. and Reis, A. and Rohde, K. and Ganten, D. and Hui, R.T. and Huebner, N.
Human Molecular Genetics 12 (11): 1273-1277. 1 June 2003

2001

Mutations in CAV3 cause mechanical hyperirritability of skeletal muscle in rippling muscle disease.
Betz, R.C. and Schoser, B.G.H. and Kasper, D. and Ricker, K. and Ramirez, A. and Stein, V. and Torbergsen, T. and Lee, Y.A. and Nothen, M.M. and Wienker, T.F. and Malin, J.P. and Propping, P. and Reis, A. and Mortier, W. and Jentsch, T.J. and Vorgerd, M. and Kubisch, C.
Nature Genetics 28 (3): 218-219. July 2001

1997

Tissue and development specific expression of multiple alternatively spliced transcripts of rat neuronal nitric oxide synthase.
Lee, M.A. and Cai, L. and Huebner, N. and Lee, Y.A. and Lindpaintner, K.
Journal of Clinical Investigation 100 (6): 1507-1512. 15 September 1997

1995

Genetische Analyse des Bluthochdrucks.
Lee, Y.A. and Huebner, N. and Ganten, D.
In: Jahrbuch 1995 der Deutschen Akademie der Naturforscher Leopoldina (Halle/Saale). Leopoldina, R.3, 41 . Dt. Akad. d. Naturforscher Leopoldina, Halle/Saale, 323-333. 1 January 1995

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