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2018

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.
Schleussner, N. and Merkel, O. and Costanza, M. and Liang, H.C. and Hummel, F. and Romagnani, C. and Durek, P. and Anagnostopoulos, I. and Hummel, M. and Jöhrens, K. and Niedobitek, A. and Griffin, P.R. and Piva, R. and Sczakiel, H.L. and Woessmann, W. and Damm-Welk, C. and Hinze, C. and Stoiber, D. and Gillissen, B. and Turner, S.D. and Kaergel, E. and von Hoff, L. and Grau, M. and Lenz, G. and Dörken, B. and Scheidereit, C. and Kenner, L. and Janz, M. and Mathas, S.
Leukemia 32 (9): 1994-2007. September 2018

2017

Graded elevation of c-Jun in Schwann cells in vivo: gene dosage determines effects on development, remyelination, tumorigenesis, and hypomyelination.
Fazal, S.V. and Gomez-Sanchez, J.A. and Wagstaff, L.J. and Musner, N. and Otto, G. and Janz, M. and Mirsky, R. and Jessen, K.R.
Journal of Neuroscience 37 (50): 12297-12313. 13 December 2017

Incorporation of brentuximab vedotin into first-line treatment of advanced classical Hodgkin's lymphoma: final analysis of a phase 2 randomised trial by the German Hodgkin Study Group.
Eichenauer, D.A. and Plütschow, A. and Kreissl, S. and Sökler, M. and Hellmuth, J.C. and Meissner, J. and Mathas, S. and Topp, M.S. and Behringer, K. and Klapper, W. and Kuhnert, G. and Dietlein, M. and Kobe, C. and Fuchs, M. and Diehl, V. and Engert, A. and Borchmann, P.
Lancet Oncology 18 (12): 1680-1687. December 2017

Subsequent malignancies among long-term survivors of Hodgkin lymphoma and non-Hodgkin lymphoma: a pooled analysis of German cancer registry data (1990-2012).
Baras, N. and Dahm, S. and Haberland, J. and Janz, M. and Emrich, K. and Kraywinkel, K. and Salama, A.
British Journal of Haematology 177 (2): 226-242. April 2017

Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma.
Wurster, K.D. and Hummel, F. and Richter, J. and Giefing, M. and Hartmann, S. and Hansmann, M.L. and Kreher, S. and Köchert, K. and Krappmann, D. and Klapper, W. and Hummel, M. and Wenzel, S.S. and Lenz, G. and Janz, M. and Dörken, B. and Siebert, R. and Mathas, S.
Leukemia 31 (3): 602-613. March 2017

Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J. and Neuenschwander, M. and Yu, Y. and Däbritz, J.H.M. and Neuendorff, N.R. and Schleich, K. and Bittner, A. and Milanovic, M. and Beuster, G. and Radetzki, S. and Specker, E. and Reimann, M. and Rosenbauer, F. and Mathas, S. and Lohneis, P. and Hummel, M. and Dörken, B. and von Kries, J.P. and Lee, S. and Schmitt, C.A.
Blood 129 (1): 71-81. 12 January 2017

2016

Hodgkin lymphoma: pathology and biology.
Mathas, S. and Hartmann, S. and Küppers, R.
Seminars in Hematology 53 (3): 139-147. July 2016

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E. and Herzog, S. and Labi, V. and Yasuda, T. and Köchert, K. and Janz, M. and Villunger, A. and Schmidt-Supprian, M. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5065-5070. 3 May 2016

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P. and Kaergel, E. and Heinig, M. and Fontaine, J.F. and Patone, G. and Muro, E.M. and Mathas, S. and Hummel, M. and Andrade-Navarro, M.A. and Hübner, N. and Scheidereit, C.
Genome Medicine 8 (1): 28. 17 March 2016

The European Hematology Association Roadmap for European Hematology Research: a consensus document.
Engert, A. and Balduini, C. and Brand, A. and Coiffier, B. and Cordonnier, C. and Doehner, H. and Duyvene' de Wit, T. and Eichinger, S. and Fibbe, W. and Green, T. and de Haas, F. and Iolascon, A. and Jaffredo, T. and Rodeghiero, F. and Salles, G. and Schuringa, J.J.
Haematologica 101 (2): 115-208. February 2016

2015

The origins of ALK translocations.
Roukos, V. and Mathas, S.
Frontiers in Bioscience 7 : 260-268. 1 June 2015

The IL-15 cytokine system provides growth and survival signals in hodgkin lymphoma and enhances the inflammatory phenotype of HRS cells.
Ullrich, K. and Blumenthal-Barby, F. and Lamprecht, B. and Koechert, K. and Lenze, D. and Hummel, M. and Mathas, S. and Doerken, B. and Janz, M.
Leukemia 29 (5): 1213-1218. May 2015

Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial.
Behringer, K. and Goergen, H. and Hitz, F. and Zijlstra, J.M. and Greil, R. and Markova, J. and Sasse, S. and Fuchs, M. and Topp, M.S. and Soekler, M. and Mathas, S. and Meissner, J. and Wilhelm, M. and Koch, P. and Lindemann, H.W. and Schalk, E. and Semrau, R. and Kriz, J. and Vieler, T. and Bentz, M. and Lange, E. and Mahlberg, R. and Hassler, A. and Vogelhuber, M. and Hahn, D. and Mezger, J. and Krause, S.W. and Skoetz, N. and Böll, B. and von Tresckow, B. and Diehl, V. and Hallek, M. and Borchmann, P. and Stein, H. and Eich, H. and Engert, A.
Lancet 385 (9976): 1418-1427. 11 April 2015

Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: its more than NF-κB!
Kreher, S. and Cauchy, P. and Bonifer, C. and Mathas, S.
Cytokine 72 (1): 115-117. March 2015

Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann, A. and Grau, M. and Erdmann, T. and Merkel, O. and Sobhiafshar, U. and Anagnostopoulos, I. and Hummel, M. and Siegert, A. and Hayford, C. and Madle, H. and Wollert-Wulf, B. and Fichtner, I. and Dörken, B. and Dirnhofer, S. and Mathas, S. and Janz, M. and Emre, N.C.T. and Rosenwald, A. and Ott, G. and Lenz, P. and Tzankov, A. and Lenz, G.
Blood 125 (1): 124-132. 1 January 2015

2014

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, S. and Bouhlel, M.A. and Cauchy, P. and Lamprecht, B. and Li, S. and Grau, M. and Hummel, F. and Köchert, K. and Anagnostopoulos, I. and Jöhrens, K. and Hummel, M. and Hiscott, J. and Wenzel, S.S. and Lenz, P. and Schneider, M. and Küppers, R. and Scheidereit, C. and Giefing, M. and Siebert, R. and Rajewsky, K. and Lenz, G. and Cockerill, P.N. and Janz, M. and Dörken, B. and Bonifer, C. and Mathas, S.
Proceedings of the National Academy of Sciences of the United States of America 111 (42): E4513-E4522. 21 October 2014

Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ.
Rehm, A. and Gätjen, M. and Gerlach, K. and Scholz, F. and Mensen, A. and Gloger, M. and Heinig, K. and Lamprecht, B. and Mathas, S. and Bégay, V. and Leutz, A. and Lipp, M. and Dörken, B. and Höpken, U.E.
Nature Communications 5 : 5057. 30 September 2014

2013

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai, H. and Wenzel, S.S. and Hailfinger, S. and Grau, M. and Kaergel, E. and Seitz, V. and Wollert-Wulf, B. and Pfeifer, M. and Wolf, A. and Frick, M. and Dietze, K. and Madle, H. and Tzankov, A. and Hummel, M. and Dörken, B. and Scheidereit, C. and Janz, M. and Lenz, P. and Thome, M. and Lenz, G.
Blood 122 (13): 2242-2250. 26 September 2013

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma.
Pfeifer, M. and Grau, M. and Lenze, D. and Wenzel, S.S. and Wolf, A. and Wollert-Wulf, B. and Dietze, K. and Nogai, H. and Storek, B. and Madle, H. and Dörken, B. and Janz, M. and Dirnhofer, S. and Lenz, P. and Hummel, M. and Tzankov, A. and Lenz, G.
Proceedings of the National Academy of Sciences of the United States of America 110 (30): 12420-12425. 23 July 2013

Structural insights into the mechanism of GTPase activation in the GIMAP family.
Schwefel, D. and Arasu, B.S. and Marino, S.F. and Lamprecht, B. and Köchert, K. and Rosenbaum, E. and Eichhorst, J. and Wiesner, B. and Behlke, J. and Rocks, O. and Mathas, S. and Daumke, O.
Structure 21 (4): 550-559. 2 April 2013

2012

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P. and Sasaki, Y. and Godinho, S.A. and Pellerin, A. and Koechert, K. and Sleckman, B.P. and de Alboran, I.M. and Janz, M. and Rodig, S. and Rajewsky, K.
Nature Immunology 13 (11): 1092-1100. November 2012

The tumour suppressor p53 is frequently nonfunctional in Sezary syndrome.
Lamprecht, B. and Kreher, S. and Moebs, M. and Sterry, W. and Doerken, B. and Janz, M. and Assaf, C. and Mathas, S.
British Journal of Dermatology 167 (2): 240-246. August 2012

2011

BAY 43-9006/Sorafenib blocks CSF1R activity and induces apoptosis in various classical Hodgkin lymphoma cell lines.
Ullrich, K. and Wurster, K.D. and Lamprecht, B. and Koechert, K. and Engert, A. and Doerken, B. and Janz, M. and Mathas, S.
British Journal of Haematology 155 (3): 398-402. November 2011

Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
Steininger, A. and Moebs, M. and Ullmann, R. and Koechert, K. and Kreher, S. and Lamprecht, B. and Anagnostopoulos, I. and Hummel, M. and Richter, J. and Beyer, M. and Janz, M. and Klemke, C.D. and Stein, H. and Doerken, B. and Sterry, W. and Schrock, E. and Mathas, S. and Assaf, C.
Journal of Experimental Medicine 208 (8): 1585-1593. 1 August 2011

Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Fagerli, U.M. and Ullrich, K. and Stuehmer, T. and Holien, T. and Koechert, K. and Holt, R.U. and Bruland, O. and Chatterjee, M. and Nogai, H. and Lenz, G. and Shaughnessy, J.D. and Mathas, S. and Sundan, A. and Bargou, R.C. and Doerken, B. and Borset, M. and Janz, M.
Oncogene 30 (28): 3198-3206. 14 July 2011

High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas.
Koechert, K. and Ullrich, K. and Kreher, S. and Aster, J.C. and Kitagawa, M. and Joehrens, K. and Anagnostopoulos, I. and Jundt, F. and Lamprecht, B. and Zimber-Strobl, U. and Stein, H. and Janz, M. and Doerken, B. and Mathas, S.
Oncogene 30 (15): 1831-1840. 14 April 2011

2010

Repeat-element driven activation of proto-oncogenes in human malignancies.
Lamprecht, B. and Bonifer, C. and Mathas, S.
Cell Cycle 9 (21): 4276-4281. November 2010

Common clonal origin of an acute B lymphoblastic leukemia and a Langerhans' cell sarcoma: evidence for hematopoietic plasticity.
Ratei, R. and Hummel, M. and Anagnostopoulos, I. and Jaehne, D. and Arnold, R. and Doerken, B. and Mathas, S. and Thomas, B. and Dudeck, O. and Ludwig, W.D. and Stein, H.
Haematologica 95 (9): 1461-1466. September 2010

Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
Lamprecht, B. and Walter, K. and Kreher, S. and Kumar, R. and Hummel, M. and Lenze, D. and Koechert, K. and Bouhlel, M.A. and Richter, J. and Soler, E. and Stadhouders, R. and Joehrens, K. and Wurster, K.D. and Callen, D.F. and Harte, M.F. and Giefing, M. and Barlow, R. and Stein, H. and Anagnostopoulos, I. and Janz, M. and Cockerill, P.N. and Siebert, R. and Doerken, B. and Bonifer, C. and Mathas, S.
Nature Medicine 16 (5): 571-579, 1p following 579. May 2010

2009

The dangers of transcription.
Mathas, S. and Misteli, T.
Cell 139 (6): 1047-1049. 11 December 2009

C/EBPβ regulates transcription factors critical for proliferation and survival of multiple myeloma cells.
Pal, R. and Janz, M. and Galson, D.L. and Gries, M. and Li, S. and Johrens, K. and Anagnostopoulos, I. and Doerken, B. and Mapara, M.Y. and Borghesi, L. and Kardava, L. and Roodman, G.D. and Milcarek, C. and Lentzsch, S.
Blood 114 (18): 3890-3898. 29 October 2009

Die molekulare Pathogenese des klassischen Hodgkin-Lymphoms [The molecular pathogenesis of classical Hodgkin lymphoma].
Mathas, S. and Doerken, B. and Janz, M.
Deutsche Medizinische Wochenschrift 134 (39): 1944-1948. September 2009

Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma.
Mathas, S. and Kreher, S. and Meaburn, K.J. and Joehrens, K. and Lamprecht, B. and Assaf, C. and Sterry, W. and Kadin, M.E. and Daibata, M. and Joos, S. and Hummel, M. and Stein, H. and Janz, M. and Anagnostopoulos, I. and Schrock, E. and Misteli, T. and Doerken, B.
Proceedings of the National Academy of Sciences of the United States of America 106 (14): 5831-5836. 7 April 2009

2008

Notch inhibition blocks multiple myeloma cell-induced osteoclast activation.
Schwarzer, R. and Kaiser, M. and Acikgoez, O. and Heider, U. and Mathas, S. and Preissner, R. and Sezer, O. and Doerken, B. and Jundt, F.
Leukemia 22 (12): 2273-2277. December 2008

Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3α.
Lamprecht, B. and Kreher, S. and Anagnostopoulos, I. and Joehrens, K. and Monteleone, G. and Jundt, F. and Stein, H. and Janz, M. and Doerken, B. and Mathas, S.
Blood 112 (8): 3339-3347. 15 October 2008

The pathogenesis of classical Hodgkin's lymphoma: what can we learn from analyses of genomic alterations in Hodgkin and Reed-Sternberg cells?
Janz, M. and Mathas, S.
Haematologica 93 (9): 1292-1295. September 2008

Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma.
Jundt, F. and Acikgoez, O. and Kwon, S.H. and Schwarzer, R. and Anagnostopoulos, I. and Wiesner, B. and Mathas, S. and Hummel, M. and Stein, H. and Reichardt, H.M. and Doerken, B.
Leukemia 22 (8): 1587-1594. August 2008

2007

The pathogenesis of classical Hodgkin's lymphoma: a model for B-cell plasticity.
Mathas, S.
Hematology Oncology Clinics of North America 21 (5): 787-804. October 2007

Loss of bHLH transcription factor E2A activity in primary effusion lymphoma confers resistance to apoptosis.
Lietz, A. and Janz, M. and Sigvardsson, M. and Jundt, F. and Doerken, B. and Mathas, S.
British Journal of Haematology 137 (4): 342-348. May 2007

Pharmacologic activation of p53-dependent and p53-independent apoptotic pathways in Hodgkin/Reed-Sternberg cells.
Janz, M. and Stuehmer, T. and Vassilev, L.T. and Bargou, R.C.
Leukemia 21 (4): 772-779. April 2007

Dendritic cell maturation stage determines susceptibility to the proteasome inhibitor bortezomib.
Subklewe, M. and Sebelin-Wulf, K. and Beier, C. and Lietz, A. and Mathas, S. and Doerken, B. and Pezzutto, A.
Human Immunology 68 (3): 147-155. March 2007

2006

Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma.
Martin-Subero, J.I. and Wlodarska, I. and Bastard, C. and Picquenot, J.M. and Hoeppner, J. and Giefing, M. and Klapper, W. and Siebert, R. and Mathas, S. and Joos, S. and Stein, H. and Doerken, B.
Blood 108 : 401-403. 1 July 2006

Reprogramming of B lymphoid cells in human lymphoma pathogenesis.
Janz, M. and Doerken, B. and Mathas, S.
Cell Cycle 5 (10): 1057-1061. 15 May 2006

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.
Sturm, I. and Stephan, C. and Gillissen, B. and Siebert, R. and Janz, M. and Radetzki, S. and Jung, K. and Loening, S. and Doerken, B. and Daniel, P.T.
Cell Death and Differentiation 13 : 619-627. April 2006

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells.
Janz, M. and Hummel, M. and Truss, M. and Wollert-Wulf, B. and Mathas, S. and Joehrens, K. and Hagemeier, C. and Bommert, K. and Stein, H. and Doerken, B. and Bargou, R.C.
Blood 107 (6): 2536-2539. 15 March 2006

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma.
Mathas, S. and Janz, M. and Hummel, F. and Hummel, M. and Wollert-Wulf, B. and Lusatis, S. and Anagnostopoulos, I. and Lietz, A. and Sigvardsson, M. and Jundt, F. and Joehrens, K. and Bommert, K. and Stein, H. and Doerken, B.
Nature Immunology 7 (2): 207-215. February 2006

2005

Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas.
Mathas, S. and Joehrens, K. and Joos, S. and Lietz, A. and Hummel, F. and Janz, M. and Jundt, F. and Anagnostopoulos, I. and Bommert, K. and Lichter, P. and Stein, H. and Scheidereit, C. and Doerken, B.
Blood 106 (13): 4287-4293. 25 August 2005

A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein beta and NF-kappaB activity in Hodgkin and anaplastic large cell lymphomas.
Jundt, F. and Raetzel, N. and Mueller, C. and Calkhoven, C.F. and Kley, K. and Mathas, S. and Lietz, A. and Leutz, A. and Doerken, B.
Blood 106 : 1801-1807. 1 January 2005

Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis.
Koh, K.R. and Janz, M. and Mapara, M.Y. and Lemke, B. and Stirling, D. and Doerken, B. and Zenke, M. and Lentzsch, S.
Blood 105 (10): 3833-3840. 1 January 2005

2004

c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.
Mathas, S. and Lietz, A. and Anagnostopoulos, I. and Hummel, F. and Wiesner, B. and Janz, M. and Jundt, F. and Hirsch, B. and Joehrens-Leder, K. and Vornlocher, H.P. and Bommert, K. and Stein, H. and Doerken, B.
Journal of Experimental Medicine 199 (8): 1041-1052. 19 April 2004

Downregulation of genes involved in DNA repair and differential expression of transcription regulators and phosphatases precede IgM-induced apoptosis in the Burkitt's lymphoma cell line BL60-2.
Schories, B. and Janz, M. and Doerken, B. and Bommert, K.
Biochimica et Biophysica Acta - Gene Structure and Expression 1676 (1): 83-95. 1 January 2004

Jagged1-induced notch signaling drives proliferation of multiple myeloma cells.
Jundt, F. and Schulze-Proebsting, K. and Anagnostopoulos, I. and Muehlinghaus, G. and Chatterjee, M. and Mathas, S. and Bargou, R.C. and Manz, R. and Stein, H. and Doerken, B.
Blood 103 (9): 3511-3515. 1 January 2004

2003

Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis.
Mathas, S. and Lietz, A. and Janz, M. and Hinz, M. and Jundt, F. and Scheidereit, C. and Bommert, K. and Doerken, B.
Blood 102 (3): 1028-1034. 1 August 2003

Macrophage inflammatory protein 1-alpha (MIP-1alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.
Lentzsch, S. and Gries, M. and Janz, M. and Bargou, R. and Doerken, B. and Mapara, M.Y.
Blood 101 (9): 3568-3573. 1 May 2003

YB-1 as a cell cycle-regulated transcription factor facilitating cyclin A and cyclin B1 gene expression.
Juerchott, K. and Bergmann, S. and Stein, U. and Walther, W. and Janz, M. and Manni, I. and Piaggio, G. and Fietze, E. and Dietel, M. and Royer, H.D.
Journal of Biological Chemistry 278 (30): 27988-27996. 1 January 2003

2002

In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp 130/STAT3 pathway.
Chatterjee, M. and Hoenemann, D. and Lentzsch, S. and Bommert, K. and Sers, C. and Herrmann, P. and Mathas, S. and Doerken, B. and Bargou, R.C.
Blood 100 (9): 3311-3318. 1 November 2002

Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
Hinz, M. and Lemke, P. and Anagnostopoulos, I. and Hacker, C. and Krappmann, D. and Mathas, S. and Doerken, B. and Zenke, M. and Stein, H. and Scheidereit, C.
Journal of Experimental Medicine 196 (5): 605-617. 2 September 2002

Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.
Mathas, S. and Hinz, M. and Anagnostopoulos, L. and Krappmann, D. and Lietz, A. and Jundt, F. and Bommert, K. and Mechta-Grigoriou, F. and Stein, H. and Doerken, B. and Scheidereit, C.
EMBO Journal 21 (15): 4104-4113. 1 August 2002

Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.
Jundt, F. and Anagnostopoulos, I. and Foerster, R. and Mathas, S. and Stein, H. and Doerken, B.
Blood 99 (9): 3398-3403. 1 May 2002

Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease.
Jundt, F. and Kley, K. and Anagnostopoulos, I. and Schulze-Proebsting, K. and Greiner, A. and Mathas, S. and Scheidereit, C. and Wirth, T. and Stein, H. and Doerken, B.
Blood 99 (8): 3060-3062. 15 April 2002

Y-box factor YB-1 predicts drug resistance and patient outcome in breast cancer independent of clinically relevant tumor biologic factors HER2, uPA and PAI-1.
Janz, M. and Harbeck, N. and Dettmar, P. and Berger, U. and Schmidt, A. and Juerchott, K. and Schmitt, M. and Royer, H.D.
International Journal of Cancer 97 (3): 278-282. 1 January 2002

2001

Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.
Hinz, M. and Loeser, P. and Mathas, S. and Krappmann, D. and Doerken, B. and Scheidereit, C.
Blood 97 (9): 2798-2807. 1 January 2001

2000

Anti-CD20-and B-cell receptor-mediated apoptosis: Evidence for shared intracellular signaling pathways.
Mathas, S. and Rickers, A. and Bommert, K. and Doerken, B. and Mapara, M.Y.
Cancer Research 60 (24): 7170-7176. 1 January 2000

Y-box factor YB-1 is associated with the centrosome during mitosis.
Janz, M. and Juerchott, K. and Karawajew, L. and Royer, H.D.
Gene Function and Disease 1 : 57-59. 1 January 2000

1999

Overexpression of IkappaBalpha without inhibition of NF-kappaB activity and mutations in the IkappaBalpha gene in Reed-Sternberg cells.
Emmerich, F. and Meiser, M. and Hummel, M. and Demel, G. and Foss, H.D. and Jundt, F. and Mathas, S. and Krappmann, D. and Scheidereit, C. and Stein, H. and Doerken, B.
Blood 94 : 3129-3134. 1 November 1999

Regulation des Zellzyklus und therapeutische Implikationen.
Royer, H.D. and Grinstein, E. and Janz, M.
Onkologe 5 : 884-890. 1 January 1999

This list was generated on Sun Dec 16 02:18:16 2018 CET.
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