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From suspected lymphoma to self-limiting lymphadenitis: Kikuchi-Fujimoto disease in focus.
Rieck, Julian, Dittmayer, Carsten, Janz, Martin
ORCID: https://orcid.org/0000-0002-1127-0044, Horst, David and Schallenberg, Simon
Journal of Hematopathology 19
(1): 30.
3 June 2026
MRD-2 in the GHSG HD21 trial assessed by a validated circulating tumor DNA sequencing assay.
Heger, Jan-Michel, Mattlener, Julia, Kaul, Helen, Ferdinandus, Justin, Schneider, Jessica, Schleifenbaum, Julia K., Schneider, Gundolf, Schaub, Valdete, Haenel, Mathias, Hellmuth, Johannes Christian, Dierlamm, Judith, Martin, Sonja, Mathas, Stephan
ORCID: https://orcid.org/0000-0001-9626-1413, Meissner, Julia, Pegtel, D. Michiel, Zijlstra, Josée M., Ossowski, Anna, Becker, Kerstin, Hallek, Michael J., von Tresckow, Bastian, Borchmann, Peter and Borchmann, Sven
Blood 147
(19): 2194-2202.
7 May 2026
FOXO1 re-expression with a dual-recombinase allele rescues class switching in germinal center B cells.
Farré Díaz, Carlota
ORCID: https://orcid.org/0000-0003-4306-2108, Kabrani, Eleni
ORCID: https://orcid.org/0000-0003-0834-9912, Winkler, Wiebke
ORCID: https://orcid.org/0000-0001-8807-9259, Blanc, Eric
ORCID: https://orcid.org/0000-0002-4369-0254, Wollert-Wulf, Brigitte
ORCID: https://orcid.org/0009-0000-0257-4049, Salomon, Claudia
ORCID: https://orcid.org/0009-0000-6723-6497, Wunderlich, F. Thomas
ORCID: https://orcid.org/0000-0002-9209-3501, Beule, Dieter
ORCID: https://orcid.org/0000-0002-3284-0632, Janz, Martin
ORCID: https://orcid.org/0000-0002-1127-0044 and Rajewsky, Klaus
ORCID: https://orcid.org/0000-0002-6633-6370
Journal of Experimental Medicine 223
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2 March 2026
Recombination junctions from antibody isotype switching classify immune and DNA repair dysfunction.
Vázquez García, Clara
ORCID: https://orcid.org/0000-0003-4583-7616, Obermayer, Benedikt
ORCID: https://orcid.org/0000-0002-9116-630X, Keller, Baerbel, Lebedin, Mikhail
ORCID: https://orcid.org/0000-0002-3877-7195, Ratswohl, Christoph
ORCID: https://orcid.org/0000-0001-5413-0730, Abolhassani, Hassan
ORCID: https://orcid.org/0000-0002-4838-0407, Busse, Antonia
ORCID: https://orcid.org/0000-0002-3470-6947, Di Virgilio, Michela
ORCID: https://orcid.org/0000-0001-5189-0793, Mathas, Stephan
ORCID: https://orcid.org/0000-0001-9626-1413, Speiser, Dorothee, Beule, Dieter
ORCID: https://orcid.org/0000-0002-3284-0632, Pan-Hammarström, Qiang
ORCID: https://orcid.org/0000-0003-1990-8804, Warnatz, Klaus
ORCID: https://orcid.org/0000-0002-1172-865X and de la Rosa, Kathrin
ORCID: https://orcid.org/0000-0003-4809-3157
Nature Communications 16
(1): 11331.
19 December 2025
MYC deregulation sensitizes cancer cells to N-myristoyltransferase inhibition.
Lueg, Gregor A., Zhang, James, Faronato, Monica, Gorelik, Andrii, Kallemeijn, Wouter W., Falciani, Francesco, Walton, Josephine, Houghton, Jack W., Vannini, Silvia, Poon, Evon, Costa, Barbara M., Solari, Roberto, Carr, Robin, Bell, Andrew S., Bartlett, Edward J., Brzezicha, Bernadette, Janz, Martin
ORCID: https://orcid.org/0000-0002-1127-0044, Chesler, Louis, Calado, Dinis P.
ORCID: https://orcid.org/0000-0001-8239-7184 and Tate, Edward W.
Cell Reports 44
(9): 116180.
23 September 2025
Impact of cellular composition and T-cell senescence of mononuclear cell concentrates on the manufacturing process of chimeric antigen receptor (CAR) T-cells.
Vučinić, Vladan
ORCID: https://orcid.org/0000-0002-8398-285X, Tumewu, Theresa, Brückner, Mandy, Kirchberg, Janine, Jentzsch, Madlen, Buhmann, Raymund, Remane, Yvonne, Hoffmann, Sandra, Ramdohr, Florian, Merz, Maximilian, Metzeler, Klaus H., Schwind, Sebastian, Herling, Carmen, Krauß, Simon M.
ORCID: https://orcid.org/0009-0009-8514-5500, Herling, Marco, Franke, Georg-Nikolaus, Grieb, Nora, Stachel, Georg, Janz, Martin
ORCID: https://orcid.org/0000-0002-1127-0044, Penack, Olaf, Bullinger, Lars
ORCID: https://orcid.org/0000-0002-5890-5510, Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958, Cross, Michael, Henschler, Reinhard
ORCID: https://orcid.org/0000-0002-5895-4259, Bach, Enrica and Platzbecker, Uwe
Transfusion 65
(9): 1650-1661.
September 2025
Fertility in patients with advanced-stage classic Hodgkin lymphoma treated with BrECADD versus eBEACOPP: a secondary analysis of the multicentre, randomised, parallel, open-label, phase 3 HD21 trial.
Ferdinandus, J., Schneider, G., Moccia, A., Greil, R., Hertzberg, M., Schaub, V., Hüttmann, A., Keil, F., Dierlamm, J., Hänel, M., Novak, U., Meissner, J., Hellmuth, J.C., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Zijlstra, J.M., Fosså, A., Viardot, A., Hertenstein, B., Martin, S., Giri, P., Kamper, P., Molin, D., Jablonski, J., Damaschin, C., Robertz, A.S., Rosenbrock, J., Fuchs, M., Borchmann, P. and Behringer, K.
Lancet Oncology 26
(8): 1081-1090.
August 2025
Comparative DNA methylation profiling of human and murine ALK‐positive B‐cell neoplasms.
Glaser, Selina
ORCID: https://orcid.org/0009-0008-2923-1829, Wagener, Rabea, Harkins, Shannon K., Voena, Claudia, Bens, Susanne, Klapper, Wolfram
ORCID: https://orcid.org/0000-0001-7208-4117, Laurent, Camille, Mathas, Sephan
ORCID: https://orcid.org/0000-0001-9626-1413, Ren, Meiqi, Sander, Sandrine
ORCID: https://orcid.org/0000-0003-4645-3366, Schnaudt‐Mastrangelo, Charlotte, Wößmann, Wilhelm
ORCID: https://orcid.org/0000-0002-6315-0888, Xerri, Luc, Ammerpohl, Ole, Zelenetz, Andrew D., Louissaint, Abner, Chiarle, Roberto and Siebert, Reiner
Genes Chromosomes & Cancer 64
(7): e70060.
July 2025
Preclinical in vitro and in vivo evidence for targeting CD74 as an effective treatment strategy for cutaneous T-cell lymphomas.
Costanza, M.
ORCID: https://orcid.org/0000-0002-8959-1083, Giordano, C., von Brünneck, A.C., Zhao, J., Makky, A., Vinh, K., Montes-Mojarro, I.A., Reisinger, F., Forchhammer, S., Witalisz-Siepracka, A., Edtmayer, S., Stoiber, D., Yin, G., Horst, D., Fischer, A., Siebert, R., Nicolay, J.P., Yin, M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Fend, F.
ORCID: https://orcid.org/0000-0002-5496-293X, Becker, J.C., Schürch, C.M., Kenner, L.
ORCID: https://orcid.org/0000-0003-2184-1338, Assaf, C., Merkel, O. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
British Journal of Dermatology 192
(5): 883-895.
May 2025
At the crossroads of infection and malignancy: the challenge of tuberculosis in migrating populations - case report and epidemiologic analysis.
Epple, Hans-Jörg, Domaszewska, Teresa, Brünneck, Ann-Christin von, Furth, Christian, Dommerich, Steffen, Lange, Christoph, Schöning, Dinah von, Maschmeyer, Georg, Bös, Lena, Schwartz, Stefan, Schneider, Thomas and Mathas, Stephan
ORCID: https://orcid.org/0000-0001-9626-1413
BMC Infectious Diseases 26
(1): 145.
26 January 2025
Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial.
Borchmann, P., Ferdinandus, J., Schneider, G., Moccia, A., Greil, R., Hertzberg, M., Schaub, V., Hüttmann, A., Keil, F., Dierlamm, J., Hänel, M., Novak, U., Meissner, J., Zimmermann, A., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Zijlstra, J.M., Fosså, A., Viardot, A., Hertenstein, B., Martin, S., Giri, P., Scholl, S., Topp, M.S., Jung, W., Vucinic, V., Beck, H.J., Kerkhoff, A., Unger, B., Rank, A., Schroers, R., zum Büschenfelde, C.M., de Wit, M., Trautmann-Grill, K., Kamper, P., Molin, D., Kreissl, S., Kaul, H., von Tresckow, B., Borchmann, S., Behringer, K., Fuchs, M., Rosenwald, A., Klapper, W., Eich, H.T., Baues, C., Zomas, A., Hallek, M., Dietlein, M., Kobe, C. and Diehl, V.
Lancet 404
(10450): 341-352.
27 July 2024
JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression.
Redmer, T.
ORCID: https://orcid.org/0000-0002-0050-9478, Raigel, M., Sternberg, C., Ziegler, R., Probst, C., Lindner, D., Aufinger, A., Limberger, T., Trachtova, K., Kodajova, P., Högler, S., Schlederer, M., Stoiber, S., Oberhuber, M., Bolis, M., Neubauer, H.A., Miranda, S., Tomberger, M., Harbusch, N.S., Garces de Los Fayos Alonso, I., Sternberg, F., Moriggl, R., Theurillat, J.P., Tichy, B., Bystry, V., Persson, J.L., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Aberger, F., Strobl, B., Pospisilova, S., Merkel, O., Egger, G., Lagger, S. and Kenner, L.
Molecular Cancer 23
(1): 114.
29 May 2024
High-dose chemotherapy and autologous haematopoietic stem-cell transplantation in older, fit patients with primary diffuse large B-cell CNS lymphoma (MARTA): a single-arm, phase 2 trial.
Schorb, E., Isbell, L.K., Kerkhoff, A., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Braulke, F., Egerer, G., Röth, A., Schliffke, S., Borchmann, P., Brunnberg, U., Kroschinsky, F., Möhle, R., Rank, A., Wellnitz, D., Kasenda, B., Pospiech, L., Wendler, J., Scherer, F., Deckert, M., Henkes, E., von Gottberg, P., Gmehlin, D., Backenstraß, M., Jensch, A., Burger-Martin, E., Grishina, O., Fricker, H., Malenica, N., Orbán, A., Duyster, J., Ihorst, G., Finke, J. and Illerhaus, G.
Lancet Haematology 11
(3): e196-e205.
March 2024
Impact of individualized treatment on recovery from fatigue and return to work in survivors of advanced stage Hodgkin Lymphoma: results from the randomized international GHSG HD18 trial.
Ferdinandus, J.
ORCID: https://orcid.org/0000-0002-3481-7997, Müller, H., Damaschin, C., Jacob, A.S., Meissner, J., Krasniqi, F., Mey, U., Schöndube, D., Thiemer, J., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Zijlstra, J., Greil, R., Feuring-Buske, M., Markova, J.
ORCID: https://orcid.org/0000-0001-8633-4789, Rüffer, J.U., Kobe, C., Eich, H.T., Baues, C., Fuchs, M., Borchmann, P. and Behringer, K.
Annals of Oncology 35
(3): 276-284.
March 2024
A prospective observational study of real-world treatment and outcome in secondary CNS lymphoma.
Habringer, S.
ORCID: https://orcid.org/0000-0002-3976-9592, Demel, U.M.
ORCID: https://orcid.org/0000-0002-6480-4185, Fietz, A.K.
ORCID: https://orcid.org/0000-0002-4395-4176, Lammer, F., Schroers, R.
ORCID: https://orcid.org/0000-0003-2744-5491, Hofer, S.
ORCID: https://orcid.org/0000-0002-0831-2098, Bairey, O., Braess, J.
ORCID: https://orcid.org/0000-0001-6528-2078, Meier-Stiegen, A.S., Stuhlmann, R., Schmidt-Hieber, M., Hoffmann, J., Zinngrebe, B., Kaiser, U., Reimer, P., Möhle, R., Fix, P., Höffkes, H.G., Langenkamp, U., Büschenfelde, C.M.Z., Hopfer, O., Stoltefuß, A., La Rosée, P.
ORCID: https://orcid.org/0000-0002-6758-7809, Blasberg, H., Jordan, K.
ORCID: https://orcid.org/0000-0001-9379-5938, Kaun, S., Meurer, A., Unteroberdörster, M., von Brünneck, A.C.
ORCID: https://orcid.org/0000-0003-4371-4292, Capper, D.
ORCID: https://orcid.org/0000-0003-1945-497X, Heppner, F.L., Chapuy, B., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Schwartz, S.
ORCID: https://orcid.org/0000-0001-8833-5793, Konietschke, F., Vajkoczy, P., Korfel, A. and Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958
European Journal of Cancer 196
: 113436.
January 2024
Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner, N.
ORCID: https://orcid.org/0009-0001-3549-5600, Cauchy, P.
ORCID: https://orcid.org/0000-0002-0659-0799, Franke, V.
ORCID: https://orcid.org/0000-0003-3606-6792, Giefing, M., Fornes, O.
ORCID: https://orcid.org/0000-0002-5969-3054, Vankadari, N.
ORCID: https://orcid.org/0000-0001-9363-080X, Assi, S.A., Costanza, M.
ORCID: https://orcid.org/0000-0002-8959-1083, Weniger, M.A., Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117, Anagnostopoulos, I.
ORCID: https://orcid.org/0000-0002-5043-6043, Bukur, T., Casarotto, M.G.
ORCID: https://orcid.org/0000-0002-0571-7671, Damm, F.
ORCID: https://orcid.org/0000-0001-5553-1173, Daumke, O.
ORCID: https://orcid.org/0000-0002-6190-1414, Edginton-White, B., Gebhardt, J.C.M.
ORCID: https://orcid.org/0000-0003-1900-600X, Grau, M., Grunwald, S.
ORCID: https://orcid.org/0000-0003-3978-6277, Hansmann, M.L., Hartmann, S.
ORCID: https://orcid.org/0000-0003-3424-1091, Huber, L., Kärgel, E., Lusatis, S., Noerenberg, D., Obier, N., Pannicke, U.
ORCID: https://orcid.org/0000-0002-0929-1794, Fischer, A.
ORCID: https://orcid.org/0000-0002-7145-2544, Reisser, A., Rosenwald, A., Schwarz, K.
ORCID: https://orcid.org/0000-0003-3178-5990, Sundararaj, S., Weilemann, A.
ORCID: https://orcid.org/0009-0001-1340-6486, Winkler, W.
ORCID: https://orcid.org/0000-0001-8807-9259, Xu, W., Lenz, G.
ORCID: https://orcid.org/0000-0002-4728-1693, Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370, Wasserman, W.W.
ORCID: https://orcid.org/0000-0001-6098-6412, Cockerill, P.N.
ORCID: https://orcid.org/0000-0002-4410-8174, Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Siebert, R., Küppers, R., Grosschedl, R.
ORCID: https://orcid.org/0000-0002-0058-1250, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Bonifer, C.
ORCID: https://orcid.org/0000-0002-4267-0825 and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Nature Communications 14
(1): 6947.
7 November 2023
Broadening the phenotypic and molecular spectrum of FINCA syndrome: Biallelic NHLRC2 variants in 15 novel individuals.
Sczakiel, H.L., Zhao, M., Wollert-Wulf, B.
ORCID: https://orcid.org/0009-0000-0257-4049, Danyel, M., Ehmke, N., Stoltenburg, C., Damseh, N., Al-Ashhab, M., Balci, T.B.
ORCID: https://orcid.org/0000-0002-5409-8387, Osmond, M., Andrade, A., Schallner, J., Porrmann, J., McDonald, K., Liao, M., Oppermann, H.
ORCID: https://orcid.org/0000-0001-9216-5918, Platzer, K.
ORCID: https://orcid.org/0000-0001-6127-6308, Dierksen, N., Mojarrad, M., Eslahi, A., Bakaeean, B., Calame, D.G., Lupski, J.R.
ORCID: https://orcid.org/0000-0001-9907-9246, Firoozfar, Z., Seyedhassani, S.M., Mohammadi, S.A., Anwaar, N., Rahman, F.
ORCID: https://orcid.org/0000-0003-1312-1007, Seelow, D.
ORCID: https://orcid.org/0000-0002-9746-4412, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Horn, D., Maroofian, R.
ORCID: https://orcid.org/0000-0001-6763-1542 and Boschann, F.
ORCID: https://orcid.org/0000-0001-9410-9290
European Journal of Human Genetics 31
(8): 905-317.
August 2023
Patient-tailored adoptive immunotherapy with EBV-specific T cells from related and unrelated donors.
Bonifacius, A.
ORCID: https://orcid.org/0000-0002-0112-967X, Lamottke, B., Tischer-Zimmermann, S., Schultze-Florey, R., Goudeva, L., Heuft, H.G., Arseniev, L., Beier, R., Beutel, G.
ORCID: https://orcid.org/0000-0001-6758-6104, Cario, G., Fröhlich, B., Greil, J.
ORCID: https://orcid.org/0000-0003-1821-1183, Hansmann, L.
ORCID: https://orcid.org/0000-0003-3790-0128, Hasenkamp, J., Höfs, M., Hundsdoerfer, P., Jost, E., Kafa, K., Kriege, O., Kröger, N.
ORCID: https://orcid.org/0000-0001-5103-9966, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Meisel, R.
ORCID: https://orcid.org/0000-0001-5230-0628, Nathrath, M., Putkonen, M., Ravens, S., Reinhardt, H.C., Sala, E., Sauer, M.G, Schmitt, C.
ORCID: https://orcid.org/0000-0002-4731-2226, Schroers, R.
ORCID: https://orcid.org/0000-0003-2744-5491, Steckel, N.K., Trappe, R.U.
ORCID: https://orcid.org/0000-0001-7565-7160, Verbeek, M., Wolff, D.
ORCID: https://orcid.org/0000-0001-7015-3190, Blasczyk, R.
ORCID: https://orcid.org/0000-0003-3875-3190, Eiz-Vesper, B. and Maecker-Kolhoff, B.
ORCID: https://orcid.org/0000-0001-8164-514X
Journal of Clinical Investigation 133
(12): e163548.
15 June 2023
Mouse models of human multiple myeloma subgroups.
Winkler, W.
ORCID: https://orcid.org/0000-0001-8807-9259, Farré Díaz, C.
ORCID: https://orcid.org/0000-0003-4306-2108, Blanc, E.
ORCID: https://orcid.org/0000-0002-4369-0254, Napieczynska, H.
ORCID: https://orcid.org/0000-0001-5091-1185, Langner, P.
ORCID: https://orcid.org/0009-0007-4313-3152, Werner, M.
ORCID: https://orcid.org/0000-0003-1200-807X, Walter, B.
ORCID: https://orcid.org/0000-0002-0844-5958, Wollert-Wulf, B.
ORCID: https://orcid.org/0009-0000-0257-4049, Yasuda, T.
ORCID: https://orcid.org/0000-0001-9997-6852, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Anagnostopoulos, I., Rosenwald, A., Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370 and Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044
Proceedings of the National Academy of Sciences of the United States of America 120
(10): e2219439120.
7 March 2023
SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma.
Heynen, G.J.J.E., Baumgartner, F.
ORCID: https://orcid.org/0000-0003-0768-1956, Heider, M., Patra, U., Holz, M., Braune, J., Kaiser, M., Schäffer, I., Bamopoulos, S.A., Ramberger, E.
ORCID: https://orcid.org/0000-0003-2760-2696, Murgai, A., Ng, Y.L.D., Demel, U.M.
ORCID: https://orcid.org/0000-0002-6480-4185, Laue, D., Liebig, S., Krüger, J., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Nogai, A., Schick, M.
ORCID: https://orcid.org/0009-0003-8626-0611, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Müller, S., Bassermann, F., Krönke, J., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958 and Wirth, M.
Blood Advances 7
(4): 469-481.
28 February 2023
Nivolumab and doxorubicin, vinblastine, and dacarbazine in early-stage unfavorable Hodgkin Lymphoma: final analysis of the randomized german Hodgkin study group phase II NIVAHL trial.
Bröckelmann, P.J.
ORCID: https://orcid.org/0000-0001-9662-9900, Bühnen, I., Meissner, J., Trautmann-Grill, K.
ORCID: https://orcid.org/0000-0002-9050-1049, Herhaus, P., Halbsguth, T.V., Schaub, V., Kerkhoff, A.
ORCID: https://orcid.org/0000-0001-6904-2821, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Bormann, M., Dickhut, A., Kaul, H., Fuchs, M.
ORCID: https://orcid.org/0000-0003-3289-3272, Kobe, C.
ORCID: https://orcid.org/0000-0002-2909-0826, Baues, C.
ORCID: https://orcid.org/0000-0003-1733-6064, Borchmann, P.
ORCID: https://orcid.org/0000-0003-3782-2158, Engert, A.
ORCID: https://orcid.org/0000-0002-1890-1523 and von Tresckow, B.
ORCID: https://orcid.org/0000-0003-1410-4487
Journal of Clinical Oncology 41
(6): 1193-1199.
20 February 2023
Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas.
Lopez, C., Schleussner, N.
ORCID: https://orcid.org/0009-0001-3549-5600, Bernhart, S.H., Kleinheinz, K., Sungalee, S., Sczakiel, H.L., Kretzmer, H., Toprak, U.H., Glaser, S., Wagener, R., Ammerpohl, O., Bens, S., Giefing, M., Sanchez, J.C.G., Apic, G., Hubschmann, D., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Kreuz, M., Mottok, A., Müller, J.M., Seufert, J., Hoffmann, S., Korbel, J.O., Russell, R.B., Schule, R., Trumper, L., Klapper, W., Radlwimmer, B., Lichter, P., Kuppers, R., Schlesner, M., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413 and Siebert, R.
Haematologica 108
(2): 543-554.
1 February 2023
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Fornes, O., Jia, A., Kuehn, H.S., Min, Q., Pannicke, U., Schleussner, N.
ORCID: https://orcid.org/0009-0001-3549-5600, Thouenon, R., Yu, Z., de Los Angeles Astbury, M., Biggs, C.M., Galicchio, M., Garcia-Campos, J.A., Gismondi, S., Gonzalez Villarreal, G., Hildebrand, K.J., Hönig, M., Hou, J., Moshous, D., Pittaluga, S., Qian, X., Rozmus, J., Schulz, A.S., Staines-Boone, A.T., Sun, B., Sun, J., Uwe, S., Venegas-Montoya, E., Wang, W., Wang, X., Ying, W., Zhai, X., Zhou, Q., Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117, André, I., Barth, T.F.E., Baumann, B., Brüstle, A., Burgio, G., Bustamante, J.C., Casanova, J.L., Casarotto, M.G., Cavazzana, M., Chentout, L., Cockburn, I.A., Costanza, M.
ORCID: https://orcid.org/0000-0002-8959-1083, Cui, C., Daumke, O.
ORCID: https://orcid.org/0000-0002-6190-1414, Del Bel, K.L., Eibel, H., Feng, X., Franke, V.
ORCID: https://orcid.org/0000-0003-3606-6792, Gebhardt, J.C.M., Götz, A., Grunwald, S.
ORCID: https://orcid.org/0000-0003-3978-6277, Hoareau, B., Hughes, T.R., Jacobsen, E.M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Jolma, A., Lagresle-Peyrou, C., Lai, N., Li, Y., Lin, S., Lu, H.Y., Lugo-Reyes, S.O., Meng, X., Möller, P., Moreno-Corona, N., Niemela, J.E., Novakovsky, G., Perez-Caraballo, J.J., Picard, C., Poggi, L., Puig-Lombardi, M.E., Randall, K.L., Reisser, A., Schmitt, Y., Seneviratne, S., Sharma, M., Stoddard, J., Sundararaj, S., Sutton, H., Tran, L.Q., Wang, Y., Wasserman, W.W., Wen, Z., Winkler, W.
ORCID: https://orcid.org/0000-0001-8807-9259, Xiong, E., Yang, A.W.H., Yu, M., Zhang, L., Zhang, H., Zhao, Q., Zhen, X., Enders, A., Kracker, S., Martinez-Barricarte, R., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Rosenzweig, S.D., Schwarz, K., Turvey, S.E. and Wang, J.Y.
Science Immunology 8
(79): eade7953.
January 2023
PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma.
Garces de Los Fayos Alonso, I., Zujo, L., Wiest, I., Kodajova, P., Timelthaler, G., Edtmayer, S., Zrimšek, M., Kollmann, S., Giordano, C., Kothmayer, M., Neubauer, H.A., Dey, S., Schlederer, M., Schmalzbauer, B.S., Limberger, T., Probst, C., Pusch, O., Högler, S., Tangermann, S., Merkel, O., Schiefer, A.I., Kornauth, C., Prutsch, N., Zimmerman, M., Abraham, B., Anagnostopoulos, J., Quintanilla-Martinez, L., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Wolf, P., Stoiber, D., Staber, P.B., Egger, G., Klapper, W., Woessmann, W., Look, T.A., Gunning, P., Turner, S.D., Moriggl, R., Lagger, S. and Kenner, L.
Molecular Cancer 21
(1): 172.
31 August 2022
Impact of the first COVID-19 lockdown in Germany on the rate of acute infections during intensive chemotherapy for Hodgkin lymphoma.
Jacob, A.S., Kaul, H., Fuchs, M., Gillessen, S., Kreissl, S., Pluetschow, A., Momotow, J., Schaub, V., Huettmann, A., Haenel, M., Zimmermann, A., Dierlamm, J., Meissner, J., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Martin, S., Engert, A., Hallek, M., Borchmann, P. and Lehmann, C.
Infection 50
(4): 925-932.
August 2022
Differentiation of cerebral neoplasms with vessel size imaging (VSI).
Foda, A.
ORCID: https://orcid.org/0000-0003-1694-1983, Kellner, E., Gunawardana, A., Gao, X., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Kufner, A., Khalil, A.A., Geran, R., Mekle, R., Fiebach, J.B. and Galinovic, I.
Clinical Neuroradiology 32
(1): 239-248.
March 2022
Second-line tisagenlecleucel or standard care in aggressive B-cell lymphoma.
Bishop, M.R., Dickinson, M., Purtill, D., Barba, P., Santoro, A., Hamad, N., Kato, K., Sureda, A., Greil, R., Thieblemont, C., Morschhauser, F., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Flinn, I., Rabitsch, W., Kwong, Y.L., Kersten, M.J, Minnema, M.C., Holte, H., Chan, E.H.L., Martinez-Lopez, J., Müller, A.M.S., Maziarz, R.T., McGuirk, J.P., Bachy, E., Le Gouill, S., Dreyling, M., Harigae, H., Bond, D., Andreadis, C., McSweeney, P., Kharfan-Dabaja, M., Newsome, S., Degtyarev, E., Awasthi, R., Del Corral, C., Andreola, G., Masood, A., Schuster, S.J., Jäger, U., Borchmann, P. and Westin, J.R.
New England Journal of Medicine 386
(7): 629-639.
17 February 2022
Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S.
ORCID: https://orcid.org/0000-0002-0736-6019, Bittner, A.
ORCID: https://orcid.org/0000-0001-6434-0950, Frick, M., Kase, J., Hoffmann, J., Trenker, C., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Bogner, C., Hüttmann, A., Dürig, J., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Marks, R., Krohn, U., Na, I.K.
ORCID: https://orcid.org/0000-0001-9902-5424, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510 and Schmitt, C.A.
ORCID: https://orcid.org/0000-0002-4731-2226
Leukemia & Lymphoma 63
(1): 84-92.
January 2022
Aberrant expression of and cell death induction by engagement of the MHC-II chaperone CD74 in anaplastic large cell lymphoma (ALCL).
Wurster, K.D., Costanza, M.
ORCID: https://orcid.org/0000-0002-8959-1083, Kreher, S., Glaser, S., Lamprecht, B., Schleussner, N.
ORCID: https://orcid.org/0009-0001-3549-5600, Anagnostopoulos, I., Hummel, M., Jöhrens, K., Stein, H., Molina, A., Diepstra, A.
ORCID: https://orcid.org/0000-0001-9239-1050, Gillissen, B., Köchert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Siebert, R., Merkel, O., Kenner, L.
ORCID: https://orcid.org/0000-0003-2184-1338, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044 and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Cancers 13
(19): 5012.
1 October 2021
Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma.
Liang, H.C.
ORCID: https://orcid.org/0000-0003-2612-3714, Costanza, M.
ORCID: https://orcid.org/0000-0002-8959-1083, Prutsch, N., Zimmerman, M.W.
ORCID: https://orcid.org/0000-0003-2489-3889, Gurnhofer, E., Montes-Mojarro, I.A.
ORCID: https://orcid.org/0000-0003-0636-7623, Abraham, B.J.
ORCID: https://orcid.org/0000-0001-8085-3027, Prokoph, N.
ORCID: https://orcid.org/0000-0002-6429-9895, Stoiber, S.
ORCID: https://orcid.org/0000-0003-3293-867X, Tangermann, S., Lobello, C., Oppelt, J.
ORCID: https://orcid.org/0000-0002-3076-4840, Anagnostopoulos, I., Hielscher, T., Pervez, S., Klapper, W.
ORCID: https://orcid.org/0000-0001-7208-4117, Zammarchi, F., Silva, D.A.
ORCID: https://orcid.org/0000-0002-3195-9009, Garcia, K.C.
ORCID: https://orcid.org/0000-0001-9273-0278, Baker, D.
ORCID: https://orcid.org/0000-0001-7896-6217, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Schleussner, N.
ORCID: https://orcid.org/0009-0001-3549-5600, Fend, F.
ORCID: https://orcid.org/0000-0002-5496-293X, Pospíšilová, Š., Janiková, A., Wallwitz, J., Stoiber, D., Simonitsch-Klupp, I., Cerroni, L., Pileri, S., de Leval, L.
ORCID: https://orcid.org/0000-0003-3994-516X, Sibon, D., Fataccioli, V., Gaulard, P., Assaf, C., Knörr, F., Damm-Welk, C., Woessmann, W., Turner, S.D.
ORCID: https://orcid.org/0000-0002-8439-4507, Look, A.T.
ORCID: https://orcid.org/0000-0001-7851-8617, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Kenner, L.
ORCID: https://orcid.org/0000-0003-2184-1338 and Merkel, O.
ORCID: https://orcid.org/0000-0001-5089-344X
Nature Communications 12
(1): 5577.
22 September 2021
Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1.
Reinke, S., Bröckelmann, P.J., Iaccarino, I., Garcia-Marquez, M., Borchmann, S., Jochims, F., Kotrova, M., Pal, K., Brüggemann, M., Hartmann, E., Sasse, S., Kobe, C., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Soekler, M., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Bormann, M., Zimmermann, A., Richter, J., Fuchs, M., von Tresckow, B., Borchmann, P., Schlößer, H., von Bergwelt-Baildon, M., Rosenwald, A., Engert, A. and Klapper, W.
Blood 136
(25): 2851-2863.
17 December 2020
B-cell-specific Myd88 L252P expression causes a premalignant gammopathy resembling IgM MGUS.
Schmidt, K., Sack, U., Graf, R.
ORCID: https://orcid.org/0000-0002-5400-9938, Winkler, W.
ORCID: https://orcid.org/0000-0001-8807-9259, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Sommermann, T.
ORCID: https://orcid.org/0000-0003-2899-0256, Kocks, C.
ORCID: https://orcid.org/0000-0003-1749-3334 and Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370
Frontiers in Immunology 11
: 602868.
1 December 2020
The transcription factor C/EBPβ orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions.
Scholz, F.
ORCID: https://orcid.org/0000-0002-0253-081X, Grau, M., Menzel, L.
ORCID: https://orcid.org/0000-0002-3816-6255, Graband, A.
ORCID: https://orcid.org/0000-0002-9038-0734, Zapukhlyak, M.
ORCID: https://orcid.org/0000-0002-2635-6940, Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Lenz, G., Rehm, A.
ORCID: https://orcid.org/0000-0001-7490-1950 and Höpken, U.E.
ORCID: https://orcid.org/0000-0002-0776-4893
Proceedings of the National Academy of Sciences of the United States of America 117
(42): 26328-26339.
20 October 2020
PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V.
ORCID: https://orcid.org/0000-0002-0077-1935, Berruezo-Llacuna, M., Altwasser, R.
ORCID: https://orcid.org/0009-0002-6216-6068, Winkler, W.
ORCID: https://orcid.org/0000-0001-8807-9259, Sundaravinayagam, D.
ORCID: https://orcid.org/0000-0003-0717-7530, Balasubramanian, S.
ORCID: https://orcid.org/0000-0003-1830-5737, Caganova, M.
ORCID: https://orcid.org/0000-0002-4576-6574, Graf, R.
ORCID: https://orcid.org/0000-0002-5400-9938, Rahjouei, A.
ORCID: https://orcid.org/0000-0003-3973-6333, Henke, M.T.
ORCID: https://orcid.org/0000-0001-6572-1667, Driesner, M., Keller, L., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117 and Di Virgilio, M.
ORCID: https://orcid.org/0000-0001-5189-0793
Journal of Experimental Medicine 217
(10): e20200137.
5 October 2020
Phase I dose escalation study of BI 836826 (CD37 antibody) in patients with relapsed or refractory B-cell non-Hodgkin lymphoma.
Kroschinsky, F., Middeke, J.M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Lenz, G., Witzens-Harig, M., Bouabdallah, R., La Rosée, P., Viardot, A., Salles, G., Kim, S.J., Kim, T.M., Ottmann, O., Chromik, J., Quinson, A.M., von Wangenheim, U., Burkard, U., Berk, A. and Schmitz, N.
ORCID: https://orcid.org/0000-0003-4938-7528
Investigational New Drugs 38
(5): 1472-1482.
October 2020
Restriction of memory B cell differentiation at the germinal center B cell positive selection stage.
Toboso-Navasa, A.
ORCID: https://orcid.org/0000-0001-8560-1507, Gunawan, A.
ORCID: https://orcid.org/0000-0002-4136-3620, Morlino, G., Nakagawa, R.
ORCID: https://orcid.org/0000-0003-2511-0444, Taddei, A., Damry, D., Patel, Y.
ORCID: https://orcid.org/0000-0003-1787-0726, Chakravarty, P., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Kassiotis, G., Brink, R.
ORCID: https://orcid.org/0000-0002-9586-3655, Eilers, M. and Calado, D.P.
ORCID: https://orcid.org/0000-0001-8239-7184
Journal of Experimental Medicine 217
(7): e20191933.
6 July 2020
Efficacy of nivolumab and AVD in early-stage unfavorable classic Hodgkin lymphoma: the randomized phase 2 German Hodgkin Study Group NIVAHL trial.
Bröckelmann, P.J., Goergen, H., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Meissner, J., Ordemann, R., Halbsguth, T.V., Sasse, S., Sökler, M., Kerkhoff, A., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Hüttmann, A., Bormann, M., Zimmermann, A., Mettler, J., Fuchs, M., von Tresckow, B., Baues, C., Rosenwald, A., Klapper, W., Kobe, C., Borchmann, P. and Engert, A.
JAMA Oncology 6
(6): 872-880.
June 2020
Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma.
Edginton-White, B.
ORCID: https://orcid.org/0000-0002-6557-676X, Cauchy, P.
ORCID: https://orcid.org/0000-0002-0659-0799, Assi, S.A., Hartmann, S., Riggs, A.G., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Cockerill, P.N.
ORCID: https://orcid.org/0000-0002-4410-8174 and Bonifer, C.
ORCID: https://orcid.org/0000-0002-4267-0825
Leukemia 33
(6): 1463-1474.
June 2019
Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V.
ORCID: https://orcid.org/0000-0003-3606-6792, McShane, E.
ORCID: https://orcid.org/0000-0002-7806-2063, Schulz-Beiss, K.W., Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Schleussner, N.
ORCID: https://orcid.org/0009-0001-3549-5600, Kolesnichenko, M.
ORCID: https://orcid.org/0000-0001-7366-9061, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Daumke, O.
ORCID: https://orcid.org/0000-0002-6190-1414, Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751, Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413 and Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129
Blood 133
(13): 1489-1494.
28 March 2019
The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.
Schleussner, N.
ORCID: https://orcid.org/0009-0001-3549-5600, Merkel, O.
ORCID: https://orcid.org/0000-0001-5089-344X, Costanza, M.
ORCID: https://orcid.org/0000-0002-8959-1083, Liang, H.C., Hummel, F., Romagnani, C.
ORCID: https://orcid.org/0000-0002-5167-7463, Durek, P., Anagnostopoulos, I., Hummel, M., Jöhrens, K., Niedobitek, A., Griffin, P.R., Piva, R., Sczakiel, H.L., Woessmann, W., Damm-Welk, C., Hinze, C.
ORCID: https://orcid.org/0000-0003-2526-1621, Stoiber, D., Gillissen, B., Turner, S.D., Kaergel, E., von Hoff, L., Grau, M., Lenz, G., Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Kenner, L., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044 and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Leukemia 32
(9): 1994-2007.
September 2018
Graded elevation of c-Jun in Schwann cells in vivo: gene dosage determines effects on development, remyelination, tumorigenesis, and hypomyelination.
Fazal, S.V., Gomez-Sanchez, J.A.
ORCID: https://orcid.org/0000-0002-6746-1800, Wagstaff, L.J., Musner, N., Otto, G.
ORCID: https://orcid.org/0000-0002-3929-948X, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Mirsky, R. and Jessen, K.R.
Journal of Neuroscience 37
(50): 12297-12313.
13 December 2017
Incorporation of brentuximab vedotin into first-line treatment of advanced classical Hodgkin's lymphoma: final analysis of a phase 2 randomised trial by the German Hodgkin Study Group.
Eichenauer, D.A., Plütschow, A., Kreissl, S., Sökler, M., Hellmuth, J.C., Meissner, J., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Topp, M.S., Behringer, K., Klapper, W., Kuhnert, G., Dietlein, M., Kobe, C., Fuchs, M., Diehl, V., Engert, A. and Borchmann, P.
Lancet Oncology 18
(12): 1680-1687.
December 2017
Subsequent malignancies among long-term survivors of Hodgkin lymphoma and non-Hodgkin lymphoma: a pooled analysis of German cancer registry data (1990-2012).
Baras, N., Dahm, S.
ORCID: https://orcid.org/0000-0002-5578-7133, Haberland, J., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Emrich, K., Kraywinkel, K. and Salama, A.
British Journal of Haematology 177
(2): 226-242.
April 2017
Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma.
Wurster, K.D., Hummel, F., Richter, J., Giefing, M., Hartmann, S., Hansmann, M.L., Kreher, S., Köchert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Krappmann, D.
ORCID: https://orcid.org/0000-0001-7640-3234, Klapper, W., Hummel, M., Wenzel, S.S., Lenz, G., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Siebert, R. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Leukemia 31
(3): 602-613.
March 2017
Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J., Neuenschwander, M.
ORCID: https://orcid.org/0000-0002-3114-7975, Yu, Y.
ORCID: https://orcid.org/0000-0003-1928-2514, Däbritz, J.H.M., Neuendorff, N.R., Schleich, K., Bittner, A.
ORCID: https://orcid.org/0000-0001-6434-0950, Milanovic, M.
ORCID: https://orcid.org/0000-0003-1860-6003, Beuster, G., Radetzki, S.
ORCID: https://orcid.org/0000-0003-2688-2868, Specker, E.
ORCID: https://orcid.org/0000-0002-9471-9520, Reimann, M.
ORCID: https://orcid.org/0000-0002-7876-0128, Rosenbauer, F.
ORCID: https://orcid.org/0000-0001-7977-9421, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Lohneis, P., Hummel, M., Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, von Kries, J.P.
ORCID: https://orcid.org/0000-0003-4716-4988, Lee, S.
ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A.
ORCID: https://orcid.org/0000-0002-4731-2226
Blood 129
(1): 71-81.
5 January 2017
Hodgkin lymphoma: pathology and biology.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Hartmann, S. and Küppers, R.
Seminars in Hematology 53
(3): 139-147.
July 2016
Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E.
ORCID: https://orcid.org/0000-0003-1421-4045, Herzog, S., Labi, V.
ORCID: https://orcid.org/0000-0001-7538-1520, Yasuda, T.
ORCID: https://orcid.org/0000-0001-9997-6852, Köchert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Villunger, A., Schmidt-Supprian, M. and Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370
Proceedings of the National Academy of Sciences of the United States of America 113
(18): 5065-5070.
3 May 2016
A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P., Kaergel, E., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Fontaine, J.F.
ORCID: https://orcid.org/0000-0002-1101-4091, Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Muro, E.M., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Hummel, M., Andrade-Navarro, M.A.
ORCID: https://orcid.org/0000-0001-6650-1711, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223 and Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129
Genome Medicine 8
(1): 28.
17 March 2016
The European Hematology Association Roadmap for European Hematology Research: a consensus document.
Engert, A., Balduini, C., Brand, A., Coiffier, B., Cordonnier, C., Doehner, H., Duyvene' de Wit, T., Eichinger, S., Fibbe, W., Green, T., de Haas, F., Iolascon, A., Jaffredo, T., Rodeghiero, F., Salles, G. and Schuringa, J.J.
Haematologica 101
(2): 115-208.
February 2016
Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial.
Behringer, K., Goergen, H., Hitz, F., Zijlstra, J.M., Greil, R., Markova, J., Sasse, S., Fuchs, M., Topp, M.S., Soekler, M., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Meissner, J., Wilhelm, M., Koch, P., Lindemann, H.W., Schalk, E., Semrau, R., Kriz, J., Vieler, T., Bentz, M., Lange, E., Mahlberg, R., Hassler, A., Vogelhuber, M., Hahn, D., Mezger, J., Krause, S.W., Skoetz, N., Böll, B., von Tresckow, B., Diehl, V., Hallek, M., Borchmann, P., Stein, H., Eich, H. and Engert, A.
Lancet 385
(9976): 1418-1427.
11 April 2015
Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann, A., Grau, M., Erdmann, T., Merkel, O., Sobhiafshar, U., Anagnostopoulos, I., Hummel, M., Siegert, A., Hayford, C., Madle, H., Wollert-Wulf, B.
ORCID: https://orcid.org/0009-0000-0257-4049, Fichtner, I., Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Dirnhofer, S., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Emre, N.C.T., Rosenwald, A., Ott, G., Lenz, P., Tzankov, A. and Lenz, G.
Blood 125
(1): 124-132.
1 January 2015
Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, S., Bouhlel, M.A., Cauchy, P., Lamprecht, B., Li, S., Grau, M., Hummel, F., Köchert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Anagnostopoulos, I., Jöhrens, K., Hummel, M., Hiscott, J., Wenzel, S.S., Lenz, P., Schneider, M., Küppers, R., Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Giefing, M., Siebert, R., Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370, Lenz, G., Cockerill, P.N., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Bonifer, C. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Proceedings of the National Academy of Sciences of the United States of America 111
(42): E4513-E4522.
21 October 2014
Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ.
Rehm, A.
ORCID: https://orcid.org/0000-0001-7490-1950, Gätjen, M., Gerlach, K., Scholz, F.
ORCID: https://orcid.org/0000-0002-0253-081X, Mensen, A., Gloger, M., Heinig, K., Lamprecht, B., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Bégay, V.
ORCID: https://orcid.org/0000-0002-9002-4211, Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X, Lipp, M.
ORCID: https://orcid.org/0000-0002-0087-2672, Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Höpken, U.E.
ORCID: https://orcid.org/0000-0002-0776-4893
Nature Communications 5
: 5057.
30 September 2014
IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai, H., Wenzel, S.S., Hailfinger, S., Grau, M., Kaergel, E., Seitz, V., Wollert-Wulf, B.
ORCID: https://orcid.org/0009-0000-0257-4049, Pfeifer, M., Wolf, A., Frick, M., Dietze, K., Madle, H., Tzankov, A., Hummel, M., Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Lenz, P., Thome, M. and Lenz, G.
Blood 122
(13): 2242-2250.
26 September 2013
PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma.
Pfeifer, M., Grau, M., Lenze, D., Wenzel, S.S., Wolf, A., Wollert-Wulf, B.
ORCID: https://orcid.org/0009-0000-0257-4049, Dietze, K., Nogai, H., Storek, B., Madle, H., Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Dirnhofer, S., Lenz, P., Hummel, M., Tzankov, A. and Lenz, G.
Proceedings of the National Academy of Sciences of the United States of America 110
(30): 12420-12425.
23 July 2013
Structural insights into the mechanism of GTPase activation in the GIMAP family.
Schwefel, D.
ORCID: https://orcid.org/0000-0002-2945-0908, Arasu, B.S.
ORCID: https://orcid.org/0000-0003-4168-8617, Marino, S.F.
ORCID: https://orcid.org/0000-0001-5696-9679, Lamprecht, B., Köchert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Rosenbaum, E., Eichhorst, J., Wiesner, B., Behlke, J., Rocks, O.
ORCID: https://orcid.org/0000-0001-6349-9193, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413 and Daumke, O.
ORCID: https://orcid.org/0000-0002-6190-1414
Structure 21
(4): 550-559.
2 April 2013
The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P.
ORCID: https://orcid.org/0000-0001-8239-7184, Sasaki, Y., Godinho, S.A., Pellerin, A., Köchert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Sleckman, B.P., de Alboran, I.M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Rodig, S. and Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370
Nature Immunology 13
(11): 1092-1100.
November 2012
The tumour suppressor p53 is frequently nonfunctional in Sezary syndrome.
Lamprecht, B., Kreher, S., Moebs, M., Sterry, W., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Assaf, C. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
British Journal of Dermatology 167
(2): 240-246.
August 2012
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
Steininger, A., Moebs, M., Ullmann, R., Koechert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Kreher, S., Lamprecht, B., Anagnostopoulos, I., Hummel, M., Richter, J., Beyer, M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Klemke, C.D., Stein, H., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Sterry, W., Schrock, E., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413 and Assaf, C.
Journal of Experimental Medicine 208
(8): 1585-1593.
1 August 2011
Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Fagerli, U.M., Ullrich, K., Stuehmer, T., Holien, T., Koechert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Holt, R.U., Bruland, O., Chatterjee, M., Nogai, H., Lenz, G., Shaughnessy, J.D., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Sundan, A., Bargou, R.C., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Borset, M. and Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044
Oncogene 30
(28): 3198-3206.
14 July 2011
High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas.
Koechert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Ullrich, K., Kreher, S., Aster, J.C., Kitagawa, M., Joehrens, K., Anagnostopoulos, I., Jundt, F., Lamprecht, B., Zimber-Strobl, U., Stein, H., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Oncogene 30
(15): 1831-1840.
14 April 2011
Repeat-element driven activation of proto-oncogenes in human malignancies.
Lamprecht, B., Bonifer, C. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Cell Cycle 9
(21): 4276-4281.
November 2010
Common clonal origin of an acute B lymphoblastic leukemia and a Langerhans' cell sarcoma: evidence for hematopoietic plasticity.
Ratei, R., Hummel, M., Anagnostopoulos, I., Jaehne, D., Arnold, R., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Thomas, B., Dudeck, O., Ludwig, W.D. and Stein, H.
Haematologica 95
(9): 1461-1466.
September 2010
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
Lamprecht, B., Walter, K., Kreher, S., Kumar, R., Hummel, M., Lenze, D., Koechert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Bouhlel, M.A., Richter, J., Soler, E., Stadhouders, R., Joehrens, K., Wurster, K.D., Callen, D.F., Harte, M.F., Giefing, M., Barlow, R., Stein, H., Anagnostopoulos, I., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Cockerill, P.N., Siebert, R., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Bonifer, C. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Nature Medicine 16
(5): 571-579, 1p following 579.
May 2010
C/EBPβ regulates transcription factors critical for proliferation and survival of multiple myeloma cells.
Pal, R., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Galson, D.L., Gries, M., Li, S., Johrens, K., Anagnostopoulos, I., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Mapara, M.Y., Borghesi, L., Kardava, L., Roodman, G.D., Milcarek, C. and Lentzsch, S.
Blood 114
(18): 3890-3898.
29 October 2009
Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Kreher, S., Meaburn, K.J., Joehrens, K., Lamprecht, B., Assaf, C., Sterry, W., Kadin, M.E., Daibata, M., Joos, S., Hummel, M., Stein, H., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Anagnostopoulos, I., Schrock, E., Misteli, T. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Proceedings of the National Academy of Sciences of the United States of America 106
(14): 5831-5836.
7 April 2009
Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3α.
Lamprecht, B., Kreher, S., Anagnostopoulos, I., Joehrens, K., Monteleone, G., Jundt, F., Stein, H., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Blood 112
(8): 3339-3347.
15 October 2008
Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma.
Jundt, F., Acikgoez, O., Kwon, S.H., Schwarzer, R., Anagnostopoulos, I., Wiesner, B., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Hummel, M., Stein, H., Reichardt, H.M. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Leukemia 22
(8): 1587-1594.
August 2008
Loss of bHLH transcription factor E2A activity in primary effusion lymphoma confers resistance to apoptosis.
Lietz, A., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Sigvardsson, M., Jundt, F., Doerken, B. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
British Journal of Haematology 137
(4): 342-348.
May 2007
Pharmacologic activation of p53-dependent and p53-independent apoptotic pathways in Hodgkin/Reed-Sternberg cells.
Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Stuehmer, T., Vassilev, L.T. and Bargou, R.C.
Leukemia 21
(4): 772-779.
April 2007
Dendritic cell maturation stage determines susceptibility to the proteasome inhibitor bortezomib.
Subklewe, M., Sebelin-Wulf, K., Beier, C., Lietz, A., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Pezzutto, A.
ORCID: https://orcid.org/0000-0002-3246-4470
Human Immunology 68
(3): 147-155.
March 2007
Reprogramming of B lymphoid cells in human lymphoma pathogenesis.
Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Cell Cycle 5
(10): 1057-1061.
15 May 2006
Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.
Sturm, I., Stephan, C., Gillissen, B., Siebert, R., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Radetzki, S.
ORCID: https://orcid.org/0000-0003-2688-2868, Jung, K., Loening, S., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Daniel, P.T.
Cell Death and Differentiation 13
: 619-627.
April 2006
Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells.
Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Hummel, M., Truss, M., Wollert-Wulf, B.
ORCID: https://orcid.org/0009-0000-0257-4049, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Joehrens, K., Hagemeier, C., Bommert, K., Stein, H., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Bargou, R.C.
Blood 107
(6): 2536-2539.
15 March 2006
Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Hummel, F., Hummel, M., Wollert-Wulf, B.
ORCID: https://orcid.org/0009-0000-0257-4049, Lusatis, S., Anagnostopoulos, I., Lietz, A., Sigvardsson, M., Jundt, F., Joehrens, K., Bommert, K., Stein, H. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Nature Immunology 7
(2): 207-215.
February 2006
Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Joehrens, K., Joos, S., Lietz, A., Hummel, F., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Jundt, F., Anagnostopoulos, I., Bommert, K., Lichter, P., Stein, H., Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129 and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 106
(13): 4287-4293.
25 August 2005
A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein beta and NF-kappaB activity in Hodgkin and anaplastic large cell lymphomas.
Jundt, F., Raetzel, N., Mueller, C., Calkhoven, C.F., Kley, K., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Lietz, A., Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 106
: 1801-1807.
1 January 2005
Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis.
Koh, K.R., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Mapara, M.Y., Lemke, B., Stirling, D., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Zenke, M. and Lentzsch, S.
Blood 105
(10): 3833-3840.
1 January 2005
c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Lietz, A., Anagnostopoulos, I., Hummel, F., Wiesner, B., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Jundt, F., Hirsch, B., Joehrens-Leder, K., Vornlocher, H.P., Bommert, K., Stein, H. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Journal of Experimental Medicine 199
(8): 1041-1052.
19 April 2004
Downregulation of genes involved in DNA repair and differential expression of transcription regulators and phosphatases precede IgM-induced apoptosis in the Burkitt's lymphoma cell line BL60-2.
Schories, B., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Bommert, K.
Biochimica et Biophysica Acta - Gene Structure and Expression 1676
(1): 83-95.
1 January 2004
Jagged1-induced notch signaling drives proliferation of multiple myeloma cells.
Jundt, F., Schulze-Proebsting, K., Anagnostopoulos, I., Muehlinghaus, G., Chatterjee, M., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Bargou, R.C., Manz, R., Stein, H. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 103
(9): 3511-3515.
1 January 2004
Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Lietz, A., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Hinz, M.
ORCID: https://orcid.org/0000-0003-2611-4121, Jundt, F., Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Bommert, K. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 102
(3): 1028-1034.
1 August 2003
Macrophage inflammatory protein 1-alpha (MIP-1alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.
Lentzsch, S., Gries, M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Bargou, R., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Mapara, M.Y.
Blood 101
(9): 3568-3573.
1 May 2003
YB-1 as a cell cycle-regulated transcription factor facilitating cyclin A and cyclin B1 gene expression.
Juerchott, K., Bergmann, S., Stein, U.
ORCID: https://orcid.org/0000-0001-7006-282X, Walther, W.
ORCID: https://orcid.org/0000-0003-2884-0231, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Manni, I., Piaggio, G., Fietze, E., Dietel, M. and Royer, H.D.
Journal of Biological Chemistry 278
(30): 27988-27996.
1 January 2003
In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp 130/STAT3 pathway.
Chatterjee, M., Hoenemann, D., Lentzsch, S., Bommert, K., Sers, C., Herrmann, P., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Bargou, R.C.
Blood 100
(9): 3311-3318.
1 November 2002
Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
Hinz, M.
ORCID: https://orcid.org/0000-0003-2611-4121, Lemke, P., Anagnostopoulos, I., Hacker, C.
ORCID: https://orcid.org/0000-0002-6545-0104, Krappmann, D.
ORCID: https://orcid.org/0000-0001-7640-3234, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Zenke, M., Stein, H. and Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129
Journal of Experimental Medicine 196
(5): 605-617.
2 September 2002
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Hinz, M.
ORCID: https://orcid.org/0000-0003-2611-4121, Anagnostopoulos, L., Krappmann, D.
ORCID: https://orcid.org/0000-0001-7640-3234, Lietz, A., Jundt, F., Bommert, K., Mechta-Grigoriou, F., Stein, H., Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129
EMBO Journal 21
(15): 4104-4113.
1 August 2002
Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.
Jundt, F., Anagnostopoulos, I., Foerster, R., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Stein, H. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 99
(9): 3398-3403.
1 May 2002
Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease.
Jundt, F., Kley, K., Anagnostopoulos, I., Schulze-Proebsting, K., Greiner, A., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Wirth, T., Stein, H. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 99
(8): 3060-3062.
15 April 2002
Y-box factor YB-1 predicts drug resistance and patient outcome in breast cancer independent of clinically relevant tumor biologic factors HER2, uPA and PAI-1.
Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Harbeck, N., Dettmar, P., Berger, U., Schmidt, A., Juerchott, K., Schmitt, M. and Royer, H.D.
International Journal of Cancer 97
(3): 278-282.
1 January 2002
Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.
Hinz, M.
ORCID: https://orcid.org/0000-0003-2611-4121, Loeser, P., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Krappmann, D.
ORCID: https://orcid.org/0000-0001-7640-3234, Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129
Blood 97
(9): 2798-2807.
1 January 2001
Anti-CD20-and B-cell receptor-mediated apoptosis: Evidence for shared intracellular signaling pathways.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Rickers, A., Bommert, K., Doerken, B. and Mapara, M.Y.
Cancer Research 60
(24): 7170-7176.
1 January 2000
Y-box factor YB-1 is associated with the centrosome during mitosis.
Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Juerchott, K., Karawajew, L. and Royer, H.D.
Gene Function and Disease 1
: 57-59.
1 January 2000
Overexpression of IkappaBalpha without inhibition of NF-kappaB activity and mutations in the IkappaBalpha gene in Reed-Sternberg cells.
Emmerich, F., Meiser, M., Hummel, M., Demel, G., Foss, H.D., Jundt, F., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Krappmann, D.
ORCID: https://orcid.org/0000-0001-7640-3234, Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Stein, H. and Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 94
: 3129-3134.
1 November 1999
Regulation des Zellzyklus und therapeutische Implikationen.
Royer, H.D., Grinstein, E. and Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044
Onkologe 5
: 884-890.
1 January 1999
Review
The origins of ALK translocations.
Roukos, V. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Frontiers in Bioscience 7
: 260-268.
1 June 2015
Die molekulare Pathogenese des klassischen Hodgkin-Lymphoms [The molecular pathogenesis of classical Hodgkin lymphoma].
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044
Deutsche Medizinische Wochenschrift 134
(39): 1944-1948.
September 2009
The pathogenesis of classical Hodgkin's lymphoma: a model for B-cell plasticity.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Hematology Oncology Clinics of North America 21
(5): 787-804.
October 2007
Letter
Gonadal function and fertility after Hodgkin lymphoma treatment with nivolumab-AVD in the 2 GHSG NIVAHL trial.
Robertz, Anne Sophie, Bühnen, Ina, Meissner, Julia, Trautmann-Grill, Karolin, Herhaus, Peter, Halbsguth, Teresa, Schaub, Valdete, Kerkhoff, Andrea, Mathas, Stephan
ORCID: https://orcid.org/0000-0001-9626-1413, Bormann, Matthias, Dickhut, Andreas
ORCID: https://orcid.org/0009-0008-9794-9875, Jaworek, Christian P.
ORCID: https://orcid.org/0009-0007-9338-2624, Fuchs, Michael, Kobe, Carsten
ORCID: https://orcid.org/0000-0002-2909-0826, Baues, Christian
ORCID: https://orcid.org/0000-0003-1733-6064, Borchmann, Peter, von Tresckow, Bastian
ORCID: https://orcid.org/0000-0003-1410-4487, Behringer, Karolin
ORCID: https://orcid.org/0000-0002-7035-1784 and Bröckelmann, Paul J.
ORCID: https://orcid.org/0000-0001-9662-9900
Blood 147
(25): 3118-3121.
18 June 2026
Clonal Hematopoiesis does not influence manufacturing of Chimeric Antigen Receptor (CAR) T-Cells.
Krauß, Simon M.
ORCID: https://orcid.org/0009-0009-8514-5500, Weibl, Konstantin, Bach, Enrica, Brückner, Mandy, Weigert, Anne, Tumewu, Theresa, Ruschpler, Elena, Vogtmann, Gunhild, Hoffmann, Sandra, Penack, Olaf
ORCID: https://orcid.org/0000-0003-4876-802X, Janz, Martin
ORCID: https://orcid.org/0000-0002-1127-0044, Buhmann, Raymund, Henschler, Reinhard, Bullinger, Lars
ORCID: https://orcid.org/0000-0002-5890-5510, Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958, Schwind, Sebastian
ORCID: https://orcid.org/0000-0002-1315-2332, Merz, Maximilian, Jentzsch, Madlen
ORCID: https://orcid.org/0000-0002-2270-0804, Franke, Georg-Nikolaus
ORCID: https://orcid.org/0000-0001-8239-002X, Herling, Marco, Platzbecker, Uwe
ORCID: https://orcid.org/0000-0003-1863-3239, Metzeler, Klaus H.
ORCID: https://orcid.org/0000-0003-3920-7490 and Vučinić, Vladan
ORCID: https://orcid.org/0000-0002-8398-285X
Bone Marrow Transplantation
3 June 2026
(In Press)
The DNA methylation status of the TERT promoter differs between subtypes of mature B-cell lymphomas.
Kouroukli, A.G., Fischer, A.
ORCID: https://orcid.org/0000-0002-7145-2544, Kretzmer, H., Chteinberg, E., Rajaram, N., Glaser, S., Kolarova, J., Bashtrykov, P., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Drexler, H.G., Ohno, H., Ammerpohl, O., Jeltsch, A.
ORCID: https://orcid.org/0000-0001-6113-9290, Siebert, R. and Bens, S.
ORCID: https://orcid.org/0009-0008-5263-495X
Blood Cancer Journal 13
(1): 98.
26 June 2023
A peculiar case of primary central nervous system T-cell lymphoma with indolent behavior.
Wasilewski, D., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Koch, A., Rosenwald, A., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Vajkoczy, P., Faust, K., Anagnostopoulos, I. and Radke, J.
ORCID: https://orcid.org/0000-0001-9860-2007
Acta Neurologica Belgica 123
(2): 667-670.
April 2022
Brentuximab vedotin-containing escalated BEACOPP variants for newly diagnosed advanced-stage classical Hodgkin lymphoma: follow-up analysis of a randomized phase II study from the German Hodgkin Study Group.
Damaschin, C., Goergen, H., Kreissl, S., Plütschow, A., Breywisch, F., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Meissner, J., Sökler, M., Topp, M.S., Vucinic, V., Zimmermann, A., von Tresckow, B., Fuchs, M., Engert, A., Borchmann, P. and Eichenauer, D.A.
ORCID: https://orcid.org/0000-0002-1927-3514
Leukemia 36
(2): 580-582.
February 2022
High-dose glucocorticoid treatment of near-fatal Bocavirus lung infection results in rapid recovery.
Obenaus, M.
ORCID: https://orcid.org/0000-0002-5090-9162, Schildgen, O., Schürmann, D., von Brünneck, A.C., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Gebauer, B., Schilling, J., Schwartz, S.
ORCID: https://orcid.org/0000-0001-8833-5793, Weissbrich, B., Schneider, T., Hofmann, J. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
ERJ Open Research 7
(2): 00060-2021.
12 April 2021
The IL-15 cytokine system provides growth and survival signals in hodgkin lymphoma and enhances the inflammatory phenotype of HRS cells.
Ullrich, K., Blumenthal-Barby, F., Lamprecht, B., Koechert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Lenze, D., Hummel, M., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044
Leukemia 29
(5): 1213-1218.
May 2015
BAY 43-9006/Sorafenib blocks CSF1R activity and induces apoptosis in various classical Hodgkin lymphoma cell lines.
Ullrich, K., Wurster, K.D., Lamprecht, B., Koechert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Engert, A., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044 and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
British Journal of Haematology 155
(3): 398-402.
November 2011
Notch inhibition blocks multiple myeloma cell-induced osteoclast activation.
Schwarzer, R., Kaiser, M., Acikgoez, O., Heider, U., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Preissner, R., Sezer, O., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Jundt, F.
Leukemia 22
(12): 2273-2277.
December 2008
Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma.
Martin-Subero, J.I., Wlodarska, I., Bastard, C., Picquenot, J.M., Hoeppner, J., Giefing, M., Klapper, W., Siebert, R., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Joos, S., Stein, H. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 108
: 401-403.
1 July 2006
Editorial
Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: its more than NF-κB!
Kreher, S., Cauchy, P., Bonifer, C. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Cytokine 72
(1): 115-117.
March 2015
The dangers of transcription.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413 and Misteli, T.
Cell 139
(6): 1047-1049.
11 December 2009
The pathogenesis of classical Hodgkin's lymphoma: what can we learn from analyses of genomic alterations in Hodgkin and Reed-Sternberg cells?
Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044 and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Haematologica 93
(9): 1292-1295.
September 2008
Preprint
In vivo sequential mutagenesis in germinal center B cells using a dual-recombinase approach: FOXO1 re-expression upon FOXO1 knockout rescues class switch recombination.
Farré Díaz, C.
ORCID: https://orcid.org/0000-0003-4306-2108, Kabrani, E.
ORCID: https://orcid.org/0000-0003-0834-9912, Winkler, W.
ORCID: https://orcid.org/0000-0001-8807-9259, Salomon, C.
ORCID: https://orcid.org/0009-0000-6723-6497, Wunderlich, F.T., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044 and Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370
bioRxiv
: 2024.05.17.592915.
22 May 2024
Co-activation of NF-κB and MYC renders cancer cells addicted to IL6 for survival and phenotypic stability.
Barbosa, R.R., Xu, A.Q., D'Andrea, D., Copley, F., Patel, H., Chakravarty, P., Clear, A., Calaminici, M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Zhang, B., Schmidt-Supprian, M., Wang, J., Gribben, J.G., Tooze, R.
ORCID: https://orcid.org/0000-0003-2915-7119, Fitzgibbon, J., Franzoso, G., Rajewsky, K. and Calado, D.P.
ORCID: https://orcid.org/0000-0001-8239-7184
bioRxiv
: 2020.04.12.038414.
13 April 2020
This list was generated on Wed Jul 1 20:11:33 2026 UTC.