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Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging.
Young, K. and Eudy, E. and Bell, R. and Loberg, M.A. and Stearns, T. and Sharma, D. and Velten, L. and Haas, S. and Filippi, M.D. and Trowbridge, J.J.
Cell Stem Cell 28 (8): 1473-1482.e7. 5 August 2021

Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics.
Velten, L. and Story, B.A. and Hernández-Malmierca, P. and Raffel, S. and Leonce, D.R. and Milbank, J. and Paulsen, M. and Demir, A. and Szu-Tu, C. and Frömel, R. and Lutz, C. and Nowak, D. and Jann, J.C. and Pabst, C. and Boch, T. and Hofmann, W.K. and Müller-Tidow, C. and Trumpp, A. and Haas, S. and Steinmetz, L.M.
Nature Communications 12 (1): 1366. 1 March 2021

Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.
Lutsik, P. and Baude, A. and Mancarella, D. and Öz, S. and Kühn, A. and Toth, R. and Hey, J. and Toprak, U.H. and Lim, J. and Nguyen, V.H. and Jiang, C. and Mayakonda, A. and Hartmann, M. and Rosemann, F. and Breuer, K. and Vonficht, D. and Grünschläger, F. and Lee, S. and Schuhmacher, M.K. and Kusevic, D. and Jauch, A. and Weichenhan, D. and Zustin, J. and Schlesner, M. and Haas, S. and Park, J.H. and Park, Y.J. and Oppermann, U. and Jeltsch, A. and Haller, F. and Fellenberg, J. and Lindroth, A.M. and Plass, C.
Nature Communications 11 (1): 5414. 27 October 2020

Single-cell lineage tracing approaches in hematology research: technical considerations.
Carrelha, J. and Lin, D.S. and Rodriguez-Fraticelli, A.E. and Luis, T.C. and Wilkinson, A.C. and Cabezas-Wallscheid, N. and Tremblay, C.S. and Haas, S.
Experimental Hematology 89 : 26-36. September 2020

Lineage commitment of hematopoietic stem cells and progenitors: insights from recent single cell and lineage tracing technologies.
Loughran, S.J. and Haas, S. and Wilkinson, A.C. and Klein, A.M. and Brand, M.
Experimental Hematology 88 : 1-6. August 2020

Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization.
Baccin, C. and Al-Sabah, J. and Velten, L. and Helbling, P.M. and Grünschläger, F. and Hernández-Malmierca, P. and Nombela-Arrieta, C. and Steinmetz, L.M. and Trumpp, A. and Haas, S.
Nature Cell Biology 22 (1): 38-48. January 2020

Technical considerations for the use of CRISPR/Cas9 in hematology research.
Gundry, M.C. and Dever, D.P. and Yudovich, D. and Bauer, D.E. and Haas, S. and Wilkinson, A.C. and Singbrant, S.
Experimental Hematology 54 : 4-11. October 2017

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.
Brocks, D. and Schmidt, C.R. and Daskalakis, M. and Jang, H.S. and Shah, N.M. and Li, D. and Li, J. and Zhang, B. and Hou, Y. and Laudato, S. and Lipka, D.B. and Schott, J. and Bierhoff, H. and Assenov, Y. and Helf, M. and Ressnerova, A. and Islam, M.S. and Lindroth, A.M. and Haas, S. and Essers, M. and Imbusch, C.D. and Brors, B. and Oehme, I. and Witt, O. and Lübbert, M. and Mallm, J.P. and Rippe, K. and Will, R. and Weichenhan, D. and Stoecklin, G. and Gerhäuser, C. and Oakes, C.C. and Wang, T. and Plass, C.
Nature Genetics 49 (7): 1052-1060. July 2017

Systemic virus infections differentially modulate cell cycle state and functionality of long-term hematopoietic stem cells in vivo.
Hirche, C. and Frenz, T. and Haas, S.F. and Döring, M. and Borst, K. and Tegtmeyer, P.K. and Brizic, I. and Jordan, S. and Keyser, K. and Chhatbar, C. and Pronk, E. and Lin, S. and Messerle, M. and Jonjic, S. and Falk, C.S. and Trumpp, A. and Essers, M.A.G. and Kalinke, U.
Cell Reports 19 (11): 2345-2356. 13 June 2017

Human haematopoietic stem cell lineage commitment is a continuous process.
Velten, L. and Haas, S.F. and Raffel, S. and Blaszkiewicz, S. and Islam, S. and Hennig, B.P. and Hirche, C. and Lutz, C. and Buss, E.C. and Nowak, D. and Boch, T. and Hofmann, W.K. and Ho, A.D. and Huber, W. and Trumpp, A. and Essers, M.A.G. and Steinmetz, L.M.
Nature Cell Biology 19 (4): 271-281. April 2017

IFNα-mediated remodeling of endothelial cells in the bone marrow niche.
Prendergast, Á.M. and Kuck, A. and van Essen, M. and Haas, S. and Blaszkiewicz, S. and Essers, M.A.G.
Haematologica 102 (3): 445-453. March 2017

Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4.
Uckelmann, H. and Blaszkiewicz, S. and Nicolae, C. and Haas, S. and Schnell, A. and Wurzer, S. and Wagener, R. and Aszodi, A. and Essers, M.A.G.
Journal of Experimental Medicine 213 (10): 1961-1971. 19 September 2016

Myc depletion induces a pluripotent dormant state mimicking diapause.
Scognamiglio, R. and Cabezas-Wallscheid, N. and Thier, M.C. and Altamura, S. and Reyes, A. and Prendergast, Á.M. and Baumgärtner, D. and Carnevalli, L.S. and Atzberger, Ann and Haas, S. and von Paleske, L. and Boroviak, T. and Wörsdörfer, P. and Essers, M.A.G. and Kloz, U. and Eisenman, R.N. and Edenhofer, F. and Bertone, P. and Huber, W. and van der Hoeven, F. and Smith, A. and Trumpp, A.
Cell 164 (4): 668-680. 11 February 2016

Transcriptional heterogeneity and lineage commitment in myeloid progenitors.
Paul, F. and Arkin, Y. and Giladi, A. and Jaitin, D.A. and Kenigsberg, E. and Keren-Shaul, H. and Winter, D. and Lara-Astiaso, D. and Gury, M. and Weiner, A. and David, E. and Cohen, N. and Lauridsen, F.K.B. and Haas, S. and Schlitzer, A. and Mildner, A. and Ginhoux, F. and Jung, S. and Trumpp, A. and Porse, B.T. and Tanay, A. and Amit, I.
Cell 163 (7): 1663-1677. 17 December 2015

Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors.
Haas, S. and Hansson, J. and Klimmeck, D. and Loeffler, D. and Velten, L. and Uckelmann, H. and Wurzer, S. and Prendergast, Á.M. and Schnell, A. and Hexel, K. and Santarella-Mellwig, R. and Blaszkiewicz, S. and Kuck, A. and Geiger, H. and Milsom, M.D. and Steinmetz, L.M. and Schroeder, T. and Trumpp, A. and Krijgsveld, J. and Essers, M.A.G.
Cell Stem Cell 17 (4): 422-34. 1 October 2015

Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing.
Lipka, D.B. and Wang, Q. and Cabezas-Wallscheid, N. and Klimmeck, D. and Weichenhan, D. and Herrmann, C. and Lier, A. and Brocks, D. and von Paleske, L. and Renders, S. and Wünsche, P. and Zeisberger, P. and Gu, L. and Haas, S. and Essers, M.A. and Brors, B. and Eils, R. and Trumpp, A. and Milsom, M.D. and Plass, C.
Cell Cycle 13 (22): 3476-3487. 10 December 2014

Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.
Cabezas-Wallscheid, N. and Klimmeck, D. and Hansson, J. and Lipka, D.B. and Reyes, A. and Wang, Q. and Weichenhan, D. and Lier, A. and von Paleske, L. and Renders, S. and Wünsche, P. and Zeisberger, P. and Brocks, D. and Gu, L. and Herrmann, C. and Haas, S. and Essers, M.A.G. and Brors, B. and Eils, R. and Huber, W. and Milsom, M.D. and Plass, C. and Krijgsveld, J. and Trumpp, A.
Cell Stem Cell 15 (4): 507-522. 2 October 2014

The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expression.
Becker, M.S. and Schmezer, P. and Breuer, R. and Haas, S.F. and Essers, M.A. and Krammer, P.H. and Li-Weber, M.
Cell Death & Disease 5 : e1000. January 2014


Hematopoietic stem cells in health and disease - insights from single-cell multi-omic approaches.
Haas, S.
Current Stem Cell Reports 6 (3): 67-76. September 2020

Single-cell and spatial transcriptomics approaches of the bone marrow microenvironment.
Al-Sabah, J. and Baccin, C. and Haas, S.
Current Opinion in Oncology 32 (2): 146-153. 1 March 2020

Causes and consequences of hematopoietic stem cell heterogeneity.
Haas, S. and Trumpp, A. and Milsom, M.D.
Cell Stem Cell 22 (5): 627-638. 3 May 2018


An intrinsic interferon program protects stem cells from viral infection.
Haas, S. and Trumpp, A.
Developmental Cell 44 (3): 279-280. 5 February 2018


Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states.
Triana, S.H. and Vonficht, D. and Jopp-Saile, L. and Raffel, S. and Lutz, R. and Leonce, D. and Ordoñez-Rueda, D. and Ramasz, B. and Boch, T. and Jann, J.C. and Nowak, D. and Hofmann, W.K. and Müller-Tidow, C. and Hübschmann, D. and Alexandrov, T. and Benes, V. and Trumpp, A. and Paulsen, M. and Velten, L. and Haas, S.
bioRxiv : 2021.03.18.435922. 2 September 2021

This list was generated on Sat Dec 4 02:20:53 2021 CET.
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