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Differential regulation of the proteome and phosphoproteome along the dorso-ventral axis of the early Drosophila embryo.
Gomez, J.M., Nolte, H., Vogelsang, E., Dey, B., Takeda, M., Giudice, G., Faxel, M., Haunold, T., Cepraga, A., Zinzen, R.P., Krüger, M., Petsalaki, E., Wang, Y.C. and Leptin, M.
eLife 13 : e99263. 3 October 2024

Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2.
Desiderio, S., Schwaller, F., Tartour, K., Padmanabhan, K., Lewin, G.R., Carroll, P. and Marmigere, F.
eLife 12 : RP89287. 22 February 2024

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor.
Aguirre, T., Hostachy, S., Dornan, G.L., Neuenschwander, M., Seyffarth, C., Haucke, V., Schütz, A., von Kries, J.P. and Fiedler, D.
eLife 21 : RP88982. 16 October 2023

Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity.
Torcal Garcia, G., Kowenz-Leutz, E., Tian, T.V, Klonizakis, A., Lerner, J., De Andres-Aguayo, L., Sapozhnikova, V., Berenguer, C., Carmona, M.P., Casadesus, M.V., Bulteau, R., Francesconi, M., Peiro, S., Mertins, P., Zaret, K., Leutz, A. and Graf, T.
eLife 12 : e83951. 27 June 2023

Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture.
Dasgupta, S., Dayagi, D.Y., Haimovich, G., Wyler, E., Olender, T., Singer, R.H., Landthaler, M. and Gerst, J.E.
eLife 12 : e83584. 30 May 2023

Comparable in vivo joint kinematics between self-reported stable and unstable knees after TKA can be explained by muscular adaptation strategies: a retrospective observational study.
Rao, L., Horn, N., Meister, N., Preiss, S., Taylor, W.R., Santuz, A. and Schütz, P.
eLife 12 : e85136. 26 April 2023

Differential ripple propagation along the hippocampal longitudinal axis.
de Filippo, R. and Schmitz, D.
eLife 12 : e85488. 13 April 2023

A searchable image resource of Drosophila GAL4-driver expression patterns with single neuron resolution.
Meissner, G.W., Nern, A., Dorman, Z., DePasquale, G.M., Forster, K., Gibney, T., Hausenfluck, J.H., He, Y., Iyer, N.A., Jeter, J., Johnson, L., Johnston, R.M., Lee, K., Melton, B., Yarbrough, B., Zugates, C.T., Clements, Jody, Goina, C., Otsuna, H., Rokicki, K., Svirskas, R.R., Aso, Y., Card, G.M., Dickson, B.J., Ehrhardt, E., Goldammer, J., Ito, M., Kainmueller, D., Korff, W., Mais, L., Minegishi, R., Namiki, S., Rubin, G.M., Sterne, G.R., Wolff, T. and Malkesman, O.
eLife 12 : e80660. 23 February 2023

Molecular characterization of the intact mouse muscle spindle using a multi-omics approach.
Bornstein, B., Heinemann-Yerushalmi, L., Krief, S., Adler, R., Dassa, B., Leshkowitz, D., Kim, M.C., Bewick, G., Banks, R.W. and Zelzer, E.
eLife 12 : e81843. 6 February 2023

Coordinated cadherin functions sculpt respiratory motor circuit connectivity.
Vagnozzi, A.N., Moore, M.T., Lin, M., Brozost, E.M., KC, R., Agarwal, A., Schwarz, L.A., Duan, X., Zampieri, N., Landmesser, L.T. and Philippidou, P.
eLife 11 : e82116. 30 December 2022

Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled.
Ronzano, R., Skarlatou, S., Barriga, B.K., Bannatyne, B.A., Bhumbra, G.S., Foster, J.D., Moore, J.D., Lancelin, C., Pocratsky, A.M., Özyurt, M.G., Smith, C.C., Todd, A.J., Maxwell, D.J., Murray, A.J., Pfaff, S.L., Brownstone, R.M., Zampieri, N. and Beato, M.
eLife 11 : e81976. 13 December 2022

The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation towards the kidney lineage.
Mansour, F., Hinze, C., Telugu, N.S., Kresoja, J., Shaheed, I.B., Mosimann, C., Diecke, S. and Schmidt-Ott, K.M.
eLife 11 : e80165. 12 October 2022

Tongue immune compartment analysis reveals spatial macrophage heterogeneity.
Lyras, E.M., Zimmermann, K., Wagner, L.K., Dörr, D., Klose, C.S.N, Fischer, C., Jung, S., Yona, S., Hovav, A.H., Stenzel, W., Dommerich, S., Conrad, T., Leutz, A. and Mildner, A.
eLife 11 : 77490. 24 June 2022

Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
Balasubramanian, S., Andreani, M., Goncalves Andrade, J., Saha, T., Sundaravinayagam, D., Garzón, J., Zhang, W., Popp, O., Hiraga, S., Rahjouei, A., Rosen, D.B., Mertins, P., Chait, B.T., Donaldson, A.D. and Di Virgilio, M.
eLife 11 : e75047. 13 April 2022

The Cl(-)-channel TMEM16A is involved in the generation of cochlear Ca(2+) waves and promotes the refinement of auditory brainstem networks in mice.
Maul, A., Huebner, A.K., Strenzke, N., Moser, T., Rübsamen, R., Jovanovic, S. and Hübner, C.A.
eLife 11 : e72251. 24 February 2022

Human MAIT cells respond to and suppress HIV-1.
Phetsouphanh, C., Phalora, P., Hackstein, C.P., Thornhill, J., Munier, C.M.L., Meyerowitz, J., Murray, L., VanVuuren, C., Goedhals, D., Drexhage, L., Moore, R., Sattentau, Q.J., Mak, J.Y., Fairlie, D.P., Fidler, S., Kelleher, A.D., Frater, J. and Klenerman, P.
eLife 10 : e50324. 24 December 2021

NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1.
Marques, C., Unterkircher, T., Kroon, P., Oldrini, B., Izzo, A., Dramaretska, Y., Ferrarese, R., Kling, E., Schnell, O., Nelander, S., Wagner, E.F., Bakiri, L., Gargiulo, G., Carro, M.S. and Squatrito, M.
eLife 10 : e64846. 17 August 2021

Met and Cxcr4 cooperate to protect skeletal muscle stem cells against inflammation-induced damage during regeneration.
Lahmann, I., Griger, J., Chen, J.S., Zhang, Y., Schülke, M. and Birchmeier-Kohler, C.
eLife 10 : e57356. 5 August 2021

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules.
Cipriani, P.G., Bay, O., Zinno, J., Gutwein, M., Gan, H.H., Mayya, V.K., Chung, G., Chen, J.X., Fahs, H., Guan, Y., Duchaine, T.F., Selbach, M., Piano, F. and Gunsalus, K.C.
eLife 10 : e60833. 3 August 2021

Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain.
Sheinman, M., Arkhipova, K., Arndt, P.F., Dutilh, B.E., Hermsen, R. and Massip, F.
eLife 10 : e62719. 9 July 2021

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.
Ho, J.S., Di Tullio, F., Schwarz, M., Low, D., Incarnato, D., Gay, F., Tabaglio, T., Zhang, J.X., Wollmann, H., Chen, L., An, O., Chan, T.H.M., Hall Hickman, A., Zheng, S., Roudko, V., Chen, S., Karz, A., Ahmed, M., He, H.H., Greenbaum, B.D., Oliviero, S., Serresi, M., Gargiulo, G., Mann, K.M., Hernando, E., Mulholland, D., Marazzi, I., Wee, D.K.B. and Guccione, E.
eLife 10 : e59654. 2 June 2021

Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors.
Thibado, J.K, Tano, J.Y., Lee, J., Salas-Estrada, L., Provasi, D., Strauss, A., Ribeiro, J.M.L., Xiang, G., Broichhagen, J., Filizola, M., Lohse, M.J. and Levitz, J.
eLife 10 : e67027. 21 April 2021

In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo.
Willimsky, G., Beier, C., Immisch, L., Papafotiou, G., Scheuplein-Schlosser, V., Goede, A., Holzhütter, H.G., Blankenstein, T. and Kloetzel, P.M.
eLife 10 : e62019. 20 April 2021

Somatostatin interneurons activated by 5-HT(2A) receptor suppress slow oscillations in medial entorhinal cortex.
de Filippo, R., Rost, B.R., Stumpf, A., Cooper, C., Tukker, J.J., Harms, C., Beed, P. and Schmitz, D.
eLife 10 : e66960. 31 March 2021

Olig3 regulates early cerebellar development.
Lowenstein, E.D., Rusanova, A., Stelzer, J., Hernaiz-Llorens, M., Schroer, A.E., Epifanova, E., Bladt, F., Isik, E.G., Buchert, S., Jia, S., Tarabykin, V. and Hernandez-Miranda, L.R.
eLife 10 : e64684. 16 February 2021

Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development.
Geusz, R.J., Wang, A., Chiou, J., Lancman, J.J., Wetton, N., Kefalopoulou, S., Wang, J., Qiu, Y., Yan, J., Aylward, A., Ren, B., Dong, P.D.S., Gaulton, K.J. and Sander, M.
eLife 10 : e59067. 5 February 2021

Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses.
Alsaleh, G., Panse, I., Swadling, L., Zhang, H., Richter, F.C., Meyer, A., Lord, J., Barnes, E., Klenerman, P., Green, C. and Simon, A.K.
eLife 9 : e57950. 15 December 2020

Apelin signaling drives vascular endothelial cells towards a pro-angiogenic state.
Helker, C.S.M., Eberlein, J., Wilhelm, K., Sugino, T., Malchow, J., Schuermann, A., Baumeister, S., Kwon, H.B., Maischein, H.M., Potente, M., Herzog, W. and Stainier, D.Y.R.
eLife 9 : e55589. 21 September 2020

A connectome and analysis of the adult Drosophila central brain.
Scheffer, L.K., Xu, C.S., Januszewski, M., Lu, Z., Takemura, S.Y., Hayworth, K.J., Huang, G.B., Shinomiya, K., Maitlin-Shepard, J., Berg, S., Clements, J., Hubbard, P.M., Katz, W.T., Umayam, L., Zhao, T., Ackerman, D., Blakely, T., Bogovic, J., Dolafi, T., Kainmueller, D., Kawase, T., Khairy, K.A., Leavitt, L., Li, P.H., Lindsey, L., Neubarth, N., Olbris, D.J., Otsuna, H., Trautman, E.T., Ito, M., Bates, A.S., Goldammer, J., Wolff, T., Svirskas, R., Schlegel, P., Neace, E.R., Knecht, C.J., Alvarado, C.X., Bailey, D.A., Ballinger, S., Borycz, J.A., Canino, B.S., Cheatham, N., Cook, M., Dreher, M., Duclos, O., Eubanks, B., Fairbanks, K., Finley, S., Forknall, N., Francis, A., Hopkins, G.P., Joyce, E.M., Kim, S.J., Kirk, N.A., Kovalyak, J., Lauchie, S.A., Lohff, A., Maldonado, C., Manley, E.A., McLin, S., Mooney, C., Ndama, M., Ogundeyi, O., Okeoma, N., Ordish, C., Padilla, N., Patrick, C., Paterson, T., Phillips, E.E., Phillips, E.M., Rampally, N., Ribeiro, C., Robertson, M.K., Rymer, J.T., Ryan, S.M., Sammons, M., Scott, A.K., Scott, A.L., Shinomiya, A., Smith, C., Smith, K., Smith, N.L., Sobeski, M.A., Suleiman, A., Swift, J., Takemura, S., Talebi, I., Tarnogorska, D., Tenshaw, E., Tokhi, T., Walsh, J.J., Yang, T., Horne, J.A., Li, F., Parekh, R., Rivlin, P.K., Jayaraman, V., Costa, M., Jefferis, G.S.X.E., Ito, K., Saalfeld, S., George, R., Meinertzhagen, I.A., Rubin, G.M., Hess, H.F., Jain, V. and Plaza, S.M.
eLife 9 : e57443. 7 September 2020

Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly.
Hong, M., Christ, A., Christa, A., Willnow, T.E. and Krauss, R.S.
eLife 9 : e60351. 2 September 2020

A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation.
Gaertner, B., van Heesch, S., Schneider-Lunitz, V., Schulz, J.F., Witte, F., Blachut, S., Nguyen, S., Wong, R., Matta, I., Hübner, N. and Sander, M.
eLife 9 : e58659. 3 August 2020

TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration.
Patkunarajah, A., Stear, J.H., Moroni, M., Schroeter, L., Blaszkiewicz, J., Tearle, J.L.E., Cox, C.D., Fuerst, C., Sánchez-Carranza, O., Ocaña Fernández, M.D.A., Fleischer, R., Eravci, M., Weise, C., Martinac, B., Biro, M., Lewin, G.R. and Poole, K.
eLife 9 : e53308. 31 March 2020

Mouse retinal cell behaviour in space and time using light sheet fluorescence microscopy.
Prahst, C., Ashrafzadeh, P., Mead, T., Figueiredo, A., Chang, K., Richardson, D., Venkaraman, L., Richards, M., Russo, A.M., Harrington, K., Ouarné, M., Pena, A., Chen, J.X., Claesson-Welsh, L., Cho, K.S., Franco, C.A. and Bentley, K.
eLife 9 : e49779. 19 February 2020

Phrenic-specific transcriptional programs shape respiratory motor output.
Vagnozzi, A.N., Garg, K., Dewitz, C., Moore, M.T., Cregg, J.M., Jeannotte, L., Zampieri, N., Landmesser, L.T. and Philippidou, P.
eLife 9 : e52859. 16 January 2020

Metabolic modulation regulates cardiac wall morphogenesis in zebrafish.
Fukuda, R., Aharonov, A., Ong, Y.T., Stone, O.A., El-Brolosy, M., Maischein, H.M., Potente, M., Tzahor, El. and Stainier, D.Y.R.
eLife 8 23 December 2019

Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1.
Zhao, X., Nedvetsky, P., Stanchi, F., Vion, A.C., Popp, O., Zühlke, K., Dittmar, G., Klussmann, E. and Gerhardt, H.
eLife 8 : e46380. 3 October 2019

RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses.
Brockmann, M.M., Maglione, M., Willmes, C.G., Stumpf, A., Bouazza, B.A., Velasquez, L.M., Grauel, M.K., Beed, P., Lehmann, M., Gimber, N., Schmoranzer, J., Sigrist, S.J., Rosenmund, C. and Schmitz, D.
eLife 8 : e43243. 19 September 2019

Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels.
Ullrich, F., Blin, S., Lazarow, K., Daubitz, T., von Kries, J.P. and Jentsch, T.J.
eLife 8 : e49187. 18 July 2019

The transcription factor Hey and nuclear lamins specify and maintain cell identity.
Flint Brodsly, N., Bitman-Lotan, E., Boico, O., Shafat, A., Monastirioti, M., Gessler, M., Delidakis, C., Rincon-Arano, H. and Orian, A.
eLife 8 : e44745. 16 July 2019

GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.
Hu, X., Matsumoto, K., Jung, R.S., Weston, T.A., Heizer, P.J., He, C., Sandoval, N.P., Allan, C.M., Tu, Y., Vinters, H.V., Liau, L.M., Ellison, R.M., Morales, J.E., Baufeld, L.J., Bayley, N.A., He, L., Betsholtz, C., Beigneux, A.P., Nathanson, D.A., Gerhardt, H., Young, S.G., Fong, L.G. and Jiang, H.
eLife 8 : e47178. 6 June 2019

Critical role for piccolo in synaptic vesicle retrieval.
Ackermann, F., Schink, K.O., Bruns, C., Izsvák, Z., Hamra, F.K., Rosenmund, C. and Garner, C.C.
eLife 8 : e46629. 10 May 2019

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.
Nandakumar, S.K., McFarland, S.K., Mateyka, L.M., Lareau, C.A., Ulirsch, J.C., Ludwig, L.S., Agarwal, G., Engreitz, J.M., Przychodzen, B., McConkey, M., Cowley, G.S., Doench, J.G., Maciejewski, J.P., Ebert, B.L., Root, D.E. and Sankaran, V.G.
eLife 8 : e44080. 9 May 2019

Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage.
Schulz, A., Müller, N.V., van de Lest, N.A., Eisenreich, A., Schmidbauer, M., Barysenka, A., Purfürst, B., Sporbert, A., Lorenzen, T., Meyer, A.M., Herlan, L., Witten, A., Rühle, F., Zhou, W., de Heer, E., Scharpfenecker, M., Panáková, D., Stoll, M. and Kreutz, R.
eLife 8 : e42068. 22 March 2019

Extensive transmission of microbes along the gastrointestinal tract.
Schmidt, T.S.B., Hayward, M.R., Coelho, L.P., Li, S.S., Costea, P.I., Voigt, A.Y., Wirbel, J., Maistrenko, O.M., Alves, R.J.C., Bergsten, E., de Beaufort, C., Sobhani, I., Heintz-Buschart, A., Sunagawa, S., Zeller, G., Wilmes, P. and Bork, P.
eLife 8 : e42693. 12 February 2019

WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids.
Yoney, A., Etoc, F., Ruzo, A., Carroll, T., Metzger, J.J., Martyn, I., Li, S., Kirst, C., Siggia, E.D. and Brivanlou, A.H.
eLife 7 : e3827. 13 November 2018

Chromatin accessibility dynamics across C. elegans development and ageing.
Jänes, J., Dong, Y., Schoof, M., Serizay, J., Appert, A., Cerrato, C., Woodbury, C., Chen, R., Gemma, C., Huang, N., Kissiov, D., Stempor, P., Steward, A., Zeiser, E., Sauer, S. and Ahringer, J.
eLife 7 : e37344. 26 October 2018

New insights into the cellular temporal response to proteostatic stress.
Rendleman, J., Cheng, Z., Maity, S., Kastelic, N., Munschauer, M., Allgoewer, K., Teo, G., Zhang, Y.B.M., Lei, A., Parker, B., Landthaler, M., Freeberg, L., Kuersten, S., Choi, H. and Vogel, C.
eLife 7 : e39054. 12 October 2018

The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.
Makarewich, C.A., Munir, A.Z., Schiattarella, G.G., Bezprozvannaya, S., Raguimova, O.N., Cho, E.E., Vidal, A.H., Robia, S.L., Bassel-Duby, R. and Olson, E.N.
eLife 7 : e38319. 9 October 2018

Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease.
Arnoux, I., Willam, M., Griesche, N., Krummeich, J., Watari, H., Offermann, N., Weber, S., Narayan Dey, P., Chen, C., Monteiro, O., Buettner, S., Meyer, K., Bano, D., Radyushkin, K., Langston, R., Lambert, J.J., Wanker, E., Methner, A., Krauss, S., Schweiger, S. and Stroh, A.
eLife 7 : e38744. 4 September 2018

Human axial progenitors generate trunk neural crest cells in vitro.
Frith, T.J.R., Granata, I., Wind, M., Stout, E., Thompson, O., Neumann, K., Stavish, D., Heath, P.R., Ortmann, D., Hackland, J.O.S., Anastassiadis, K., Gouti, M., Briscoe, J., Wilson, V., Johnson, S.L., Placzek, M., Guarracino, M.R., Andrews, P.W. and Tsakiridis, A.
eLife 7 : e35786. 10 August 2018

Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity.
Farsi, Z., Gowrisankaran, S., Krunic, M., Rammner, B., Woehler, A., Lafer, E.M., Mim, C., Jahn, R. and Milosevic, I.
eLife 7 : e32569. 13 April 2018

Multi-view light-sheet imaging and tracking with the MaMuT software reveals the cell lineage of a direct developing arthropod limb.
Wolff, C., Tinevez, J.Y., Pietzsch, T., Stamataki, E., Harich, B., Guignard, L., Preibisch, S., Shorte, S., Keller, P.J., Tomancak, P. and Pavlopoulos, A.
eLife 7 : e34410. 29 March 2018

NOTCH activity differentially affects alternative cell fate acquisition and maintenance.
Cheung, L., Le Tissier, P., Goldsmith, S.G., Treier, M., Lovell-Badge, R. and Rizzoti, K.
eLife 7 : e33318. 26 March 2018

Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning.
Morgani, S.M., Metzger, J.J., Nichols, J., Siggia, E.D. and Hadjantonakis, A.K.
eLife 7 : e32839. 7 February 2018

YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development.
Neto, F., Klaus-Bergmann, A., Ong, Y.T., Alt, S., Vion, A.C., Szymborska, A., Carvalho, J.R., Hollfinger, I., Bartels-Klein, E., Franco, C.A., Potente, M. and Gerhardt, H.
eLife 7 : e31037. 5 February 2018

Cell-accurate optical mapping across the entire developing heart.
Weber, M., Scherf, N., Meyer, A.M., Panáková, D., Kohl, P. and Huisken, J.
eLife 6 : e28307. 29 December 2017

A synthetic biology approach to probing nucleosome symmetry.
Ichikawa, Y., Connelly, C.F., Appleboim, A., Miller, T.C., Jacobi, H., Abshiru, N.A., Chou, H.J., Chen, Y., Sharma, U., Zheng, Y., Thomas, P.M., Chen, H.V., Bajaj, V., Müller, C.W., Kelleher, N.L., Friedman, N., Bolon, D.N.A., Rando, O.J. and Kaufman, P.D.
eLife 6 : e28836. 12 September 2017

Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin.
Paeger, L., Karakasilioti, I., Altmüller, J., Frommolt, P., Brüning, J. and Kloppenburg, P.
eLife 6 : e25770. 20 June 2017

Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts.
Werth, M., Schmidt-Ott, K.M., Leete, T., Qiu, A., Hinze, C., Viltard, M., Paragas, N., Shawber, C.J., Yu, W., Lee, P., Chen, X., Sarkar, A., Mu, W., Rittenberg, A., Lin, C.S., Kitajewski, J., Al-Awqati, Q. and Barasch, J.
eLife 6 : e24265. 3 June 2017

Loss of Ptpn11 (Shp2) drives satellite cells into quiescence.
Griger, J., Schneider, R., Lahmann, I., Schöwel, V., Keller, C., Spuler, S., Nazare, M. and Birchmeier, C.
eLife 6 : e21552. 2 May 2017

Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes.
Servin-Vences, M.R., Moroni, M., Lewin, G.R. and Poole, K.
eLife 6 : e21074. 30 January 2017

Domain-swapped T cell receptors improve the safety of TCR gene therapy.
Bethune, M.T., Gee, M.H., Bunse, M., Lee, M.S., Gschweng, E.H., Pagadala, M.S., Zhou, J., Cheng, D., Heath, J.R., Kohn, D.B., Kuhns, M.S., Uckert, W. and Baltimore, D.
eLife 5 : e19095. 8 November 2016

Loss of MeCP2 disrupts cell autonomous and autocrine BDNF signaling in mouse glutamatergic neurons.
Sampathkumar, C., Wu, Y.J., Vadhvani, M., Trimbuch, T., Eickholt, B. and Rosenmund, C.
eLife 5 : e19374. 26 October 2016

Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice.
Carmona, R., Canete, A., Cano, E., Ariza, L., Rojas, A. and Munoz-Chapuli, R.
eLife 5 : e16009. 19 September 2016

Increasing Notch signaling antagonizes PRC2-mediated silencing to promote reprograming of germ cells into neurons.
Seelk, S., Adrian-Kalchhauser, I., Hargitai, B., Hajduskova, M., Gutnik, S., Tursun, B. and Ciosk, R.
eLife 5 : e15477. 7 September 2016

Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis.
Esteves de Lima, J., Bonnin, M.A., Birchmeier, C. and Duprez, D.
eLife 5 : e15593. 24 August 2016

Conserved functional antagonism of CELF 1 and MBNL proteins controls stem cell-specific alternative splicing in planarians.
Solana, J., Irimia, M., Ayoub, S., Orejuela, M.R., Zywitza, V., Jens, M., Tapial, J., Ray, D., Morris, Q.D., Hughes, T.R., Blencowe, B.J. and Rajewsky, N.
eLife 5 : e16797. 9 August 2016

Different promoter affinities account for specificity in MYC-dependent gene regulation.
Lorenzin, F., Benary, U., Baluapuri, A., Walz, S., Jung, L.A., von Eyss, B., Kisker, C., Wolf, J., Eilers, M. and Wolf, E.
eLife 5 : e15161. 27 July 2016

Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit.
Hatzold, J., Beleggia, F., Herzig, H., Altmüller, J., Nürnberg, P., Bloch, W., Wollnik, B. and Hammerschmidt, M.
eLife 5 : e14277. 15 July 2016

Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration.
Barrionuevo, F.J., Hurtado, A., Kim, G.J., Real, F.M., Bakkali, M., Kopp, J.L., Sander, M., Scherer, G., Burgos, M. and Jiménez, R.
eLife 5 : e15635. 21 June 2016

Cell-specific synaptic plasticity induced by network oscillations.
Zarnadze, S., Bäuerle, P., Santos-Torres, J., Böhm, C., Schmitz, D., Geiger, J.R.P., Dugladze, T. and Gloveli, T.
eLife 5 : e14912. 24 May 2016

Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion.
Ubezio, B., Blanco, R.A., Geudens, I., Stanchi, F., Mathivet, T., Jones, M.L., Ragab, A., Bentley, K. and Gerhardt, H.
eLife 5 : e12167. 13 April 2016

The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.
Kabat, A.M., Harrison, O.J., Riffelmacher, T., Moghaddam, A.E., Pearson, C.F., Laing, A., Abeler-Dörner, L., Forman, S.P., Grencis, R.K., Sattentau, Q., Simon, A.K., Pott, J. and Maloy, K.J.
eLife 5 : e12444. 11 March 2016

Temporal modulation of collective cell behavior controls vascular network topology.
Kur, E., Kim, J., Tata, A., Comin, C.H., Harrington, K.I., Costa, L.d.F., Bentley, K. and Gu, C.
eLife 5 : e13212. 24 February 2016

Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling.
Franco, C.A., Jones, M.L., Bernabeu, M.O., Vion, A.C., Barbacena, P., Fan, J., Mathivet, T., Fonseca, C.G., Ragab, A., Yamaguchi, T.P., Coveney, P.V., Lang, R.A. and Gerhardt, H.
eLife 5 : e07727. 4 February 2016

Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells.
Dias, J.D., Rito, T., Torlai Triglia, E., Kukalev, A., Ferrai, C., Chotalia, M., Brookes, E., Kimura, H. and Pombo, A.
eLife 4 : e11215. 19 December 2015

An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence.
Frahm, S., Antolin-Fontes, B., Goerlich, A., Zander, J.F., Ahnert-Hilger, G. and Ibanez-Tallon, I.
eLife 4 : e11396. 1 December 2015

Genomic DNA transposition induced by human PGBD5.
Henssen, A.G., Henaff, E., Jiang, E., Eisenberg, A.R., Carson, J.R., Villasante, C.M., Ray, M., Still, E., Burns, M., Gandara, J., Feschotte, C., Mason, C.E. and Kentsis, A.
eLife 4 : e10565. 25 September 2015

Drep-2 is a novel synaptic protein important for learning and memory.
Andlauer, T.F.M., Scholz-Kornehl, S., Tian, R., Kirchner, M., Babikir, H.A., Depner, H., Loll, B., Quentin, C., Gupta, V.K., Holt, M.G., Dipt, S., Cressy, M., Wahl, M.C., Fiala, A., Selbach, M., Schwärzel, M. and Sigrist, S.J.
eLife 3 : e03895. 13 November 2014

Autophagy is a critical regulator of memory CD8(+) T cell formation.
Puleston, D.J., Zhang, H., Powell, T.J., Lipina, E., Sims, S., Panse, I., Watson, A.S., Cerundolo, V., Townsend, A.R., Klenerman, P. and Simon, A.K.
eLife 3 : e03706. 11 November 2014

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control.
Bartha, I., Carlson, J.M., Brumme, C.J., McLaren, P.J., Brumme, Z.L., John, M., Haas, D.W., Martinez-Picado, J., Dalmau, J., López-Galíndez, C., Casado, C., Rauch, A., Günthard, H.F., Bernasconi, E., Vernazza, P., Klimkait, T., Yerly, S., O'Brien, S.J., Listgarten, J., Pfeifer, N., Lippert, C., Fusi, N., Kutalik, Z., Allen, T.M., Müller, V., Harrigan, P.R., Heckerman, D., Telenti, A. and Fellay, J.
eLife 2 : e01123. 29 October 2013

In situ structural analysis of the Yersinia enterocolitica injectisome.
Kudryashev, M., Stenta, M., Schmelz, S., Amstutz, M., Wiesand, U., Castaño-Díez, D., Degiacomi, M.T., Münnich, S., Bleck, C.K., Kowal, J., Diepold, A., Heinz, D.W., Dal Peraro, M., Cornelis, G.R. and Stahlberg, H.
eLife 2 : e00792. 30 July 2013

Review

Eleven strategies for making reproducible research and open science training the norm at research institutions.
Kohrs, F.E., Auer, S., Bannach-Brown, A., Fiedler, S., Haven, T.L., Heise, V., Holman, C., Azevedo, F., Bernard, R., Bleier, A., Bössel, N., Cahill, B.P., Castro, L.J., Ehrenhofer, A., Eichel, K., Frank, M., Frick, C., Friese, M., Gärtner, A., Gierend, K., Grüning, D.J., Hahn, L., Hülsemann, M., Ihle, M., Illius, S., König, L., König, M., Kulke, L., Kutlin, A., Lammers, F., Mehler, D.M.A., Miehl, C., Müller-Alcazar, A., Neuendorf, C., Niemeyer, H., Pargent, F., Peikert, A., Pfeuffer, C.U., Reinecke, R., Röer, J.P., Rohmann, J.L., Sánchez-Tójar, A., Scherbaum, S., Sixtus, E., Spitzer, L., Straßburger, V.M., Weber, M., Whitmire, C.J., Zerna, J., Zorbek, D., Zumstein, P. and Weissgerber, T.L.
eLife 12 : e89736. 23 November 2023

Editorial

A survey of travel behaviour among scientists in Germany and the potential for change.
Haage, V.
eLife 9 : e56765. 28 May 2020

CO(2) in the spotlight.
Hernandez-Miranda, L.R. and Birchmeier, C.
eLife 4 : e08086. 13 May 2015