2024
Differential regulation of the proteome and phosphoproteome along the dorso-ventral axis of the early Drosophila embryo.
Gomez, J.M., Nolte, H., Vogelsang, E., Dey, B., Takeda, M., Giudice, G., Faxel, M., Haunold, T., Cepraga, A., Zinzen, R.P., Krüger, M., Petsalaki, E., Wang, Y.C. and Leptin, M.
eLife 13
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3 October 2024
Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2.
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eLife 12
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22 February 2024
2023
Eleven strategies for making reproducible research and open science training the norm at research institutions.
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eLife 12
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23 November 2023
An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor.
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eLife 21
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16 October 2023
Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity.
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eLife 12
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27 June 2023
Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture.
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eLife 12
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30 May 2023
Comparable in vivo joint kinematics between self-reported stable and unstable knees after TKA can be explained by muscular adaptation strategies: a retrospective observational study.
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eLife 12
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26 April 2023
Differential ripple propagation along the hippocampal longitudinal axis.
de Filippo, R. and Schmitz, D.
eLife 12
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13 April 2023
A searchable image resource of Drosophila GAL4-driver expression patterns with single neuron resolution.
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eLife 12
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23 February 2023
Molecular characterization of the intact mouse muscle spindle using a multi-omics approach.
Bornstein, B., Heinemann-Yerushalmi, L., Krief, S., Adler, R., Dassa, B., Leshkowitz, D., Kim, M.C., Bewick, G., Banks, R.W. and Zelzer, E.
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6 February 2023
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Coordinated cadherin functions sculpt respiratory motor circuit connectivity.
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eLife 11
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30 December 2022
Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled.
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eLife 11
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13 December 2022
The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation towards the kidney lineage.
Mansour, F., Hinze, C., Telugu, N.S., Kresoja, J., Shaheed, I.B., Mosimann, C., Diecke, S. and Schmidt-Ott, K.M.
eLife 11
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12 October 2022
Tongue immune compartment analysis reveals spatial macrophage heterogeneity.
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eLife 11
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24 June 2022
Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
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eLife 11
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13 April 2022
The Cl(-)-channel TMEM16A is involved in the generation of cochlear Ca(2+) waves and promotes the refinement of auditory brainstem networks in mice.
Maul, A., Huebner, A.K., Strenzke, N., Moser, T., Rübsamen, R., Jovanovic, S. and Hübner, C.A.
eLife 11
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24 February 2022
2021
Human MAIT cells respond to and suppress HIV-1.
Phetsouphanh, C., Phalora, P., Hackstein, C.P., Thornhill, J., Munier, C.M.L., Meyerowitz, J., Murray, L., VanVuuren, C., Goedhals, D., Drexhage, L., Moore, R., Sattentau, Q.J., Mak, J.Y., Fairlie, D.P., Fidler, S., Kelleher, A.D., Frater, J. and Klenerman, P.
eLife 10
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24 December 2021
NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1.
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eLife 10
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17 August 2021
Met and Cxcr4 cooperate to protect skeletal muscle stem cells against inflammation-induced damage during regeneration.
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eLife 10
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5 August 2021
Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules.
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eLife 10
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3 August 2021
Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain.
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eLife 10
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9 July 2021
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.
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eLife 10
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2 June 2021
Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors.
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eLife 10
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21 April 2021
In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo.
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eLife 10
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20 April 2021
Somatostatin interneurons activated by 5-HT(2A) receptor suppress slow oscillations in medial entorhinal cortex.
de Filippo, R., Rost, B.R., Stumpf, A., Cooper, C., Tukker, J.J., Harms, C., Beed, P. and Schmitz, D.
eLife 10
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31 March 2021
Olig3 regulates early cerebellar development.
Lowenstein, E.D., Rusanova, A., Stelzer, J., Hernaiz-Llorens, M., Schroer, A.E., Epifanova, E., Bladt, F., Isik, E.G., Buchert, S., Jia, S., Tarabykin, V. and Hernandez-Miranda, L.R.
eLife 10
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16 February 2021
Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development.
Geusz, R.J., Wang, A., Chiou, J., Lancman, J.J., Wetton, N., Kefalopoulou, S., Wang, J., Qiu, Y., Yan, J., Aylward, A., Ren, B., Dong, P.D.S., Gaulton, K.J. and Sander, M.
eLife 10
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5 February 2021
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Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses.
Alsaleh, G., Panse, I., Swadling, L., Zhang, H., Richter, F.C., Meyer, A., Lord, J., Barnes, E., Klenerman, P., Green, C. and Simon, A.K.
eLife 9
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15 December 2020
Apelin signaling drives vascular endothelial cells towards a pro-angiogenic state.
Helker, C.S.M., Eberlein, J., Wilhelm, K., Sugino, T., Malchow, J., Schuermann, A., Baumeister, S., Kwon, H.B., Maischein, H.M., Potente, M., Herzog, W. and Stainier, D.Y.R.
eLife 9
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21 September 2020
A connectome and analysis of the adult Drosophila central brain.
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eLife 9
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7 September 2020
Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly.
Hong, M., Christ, A., Christa, A., Willnow, T.E. and Krauss, R.S.
eLife 9
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2 September 2020
A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation.
Gaertner, B., van Heesch, S., Schneider-Lunitz, V., Schulz, J.F., Witte, F., Blachut, S., Nguyen, S., Wong, R., Matta, I., Hübner, N. and Sander, M.
eLife 9
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3 August 2020
A survey of travel behaviour among scientists in Germany and the potential for change.
Haage, V.
eLife 9
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28 May 2020
TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration.
Patkunarajah, A., Stear, J.H., Moroni, M., Schroeter, L., Blaszkiewicz, J., Tearle, J.L.E., Cox, C.D., Fuerst, C., Sánchez-Carranza, O., Ocaña Fernández, M.D.A., Fleischer, R., Eravci, M., Weise, C., Martinac, B., Biro, M., Lewin, G.R. and Poole, K.
eLife 9
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31 March 2020
Mouse retinal cell behaviour in space and time using light sheet fluorescence microscopy.
Prahst, C., Ashrafzadeh, P., Mead, T., Figueiredo, A., Chang, K., Richardson, D., Venkaraman, L., Richards, M., Russo, A.M., Harrington, K., Ouarné, M., Pena, A., Chen, J.X., Claesson-Welsh, L., Cho, K.S., Franco, C.A. and Bentley, K.
eLife 9
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19 February 2020
Phrenic-specific transcriptional programs shape respiratory motor output.
Vagnozzi, A.N., Garg, K., Dewitz, C., Moore, M.T., Cregg, J.M., Jeannotte, L., Zampieri, N., Landmesser, L.T. and Philippidou, P.
eLife 9
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16 January 2020
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Metabolic modulation regulates cardiac wall morphogenesis in zebrafish.
Fukuda, R., Aharonov, A., Ong, Y.T., Stone, O.A., El-Brolosy, M., Maischein, H.M., Potente, M., Tzahor, El. and Stainier, D.Y.R.
eLife 8
23 December 2019
Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1.
Zhao, X., Nedvetsky, P., Stanchi, F., Vion, A.C., Popp, O., Zühlke, K., Dittmar, G., Klussmann, E. and Gerhardt, H.
eLife 8
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3 October 2019
RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses.
Brockmann, M.M., Maglione, M., Willmes, C.G., Stumpf, A., Bouazza, B.A., Velasquez, L.M., Grauel, M.K., Beed, P., Lehmann, M., Gimber, N., Schmoranzer, J., Sigrist, S.J., Rosenmund, C. and Schmitz, D.
eLife 8
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19 September 2019
Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels.
Ullrich, F., Blin, S., Lazarow, K., Daubitz, T., von Kries, J.P. and Jentsch, T.J.
eLife 8
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18 July 2019
The transcription factor Hey and nuclear lamins specify and maintain cell identity.
Flint Brodsly, N., Bitman-Lotan, E., Boico, O., Shafat, A., Monastirioti, M., Gessler, M., Delidakis, C., Rincon-Arano, H. and Orian, A.
eLife 8
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16 July 2019
GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.
Hu, X., Matsumoto, K., Jung, R.S., Weston, T.A., Heizer, P.J., He, C., Sandoval, N.P., Allan, C.M., Tu, Y., Vinters, H.V., Liau, L.M., Ellison, R.M., Morales, J.E., Baufeld, L.J., Bayley, N.A., He, L., Betsholtz, C., Beigneux, A.P., Nathanson, D.A., Gerhardt, H., Young, S.G., Fong, L.G. and Jiang, H.
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6 June 2019
Critical role for piccolo in synaptic vesicle retrieval.
Ackermann, F., Schink, K.O., Bruns, C., Izsvák, Z., Hamra, F.K., Rosenmund, C. and Garner, C.C.
eLife 8
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10 May 2019
Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.
Nandakumar, S.K., McFarland, S.K., Mateyka, L.M., Lareau, C.A., Ulirsch, J.C., Ludwig, L.S., Agarwal, G., Engreitz, J.M., Przychodzen, B., McConkey, M., Cowley, G.S., Doench, J.G., Maciejewski, J.P., Ebert, B.L., Root, D.E. and Sankaran, V.G.
eLife 8
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9 May 2019
Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage.
Schulz, A., Müller, N.V., van de Lest, N.A., Eisenreich, A., Schmidbauer, M., Barysenka, A., Purfürst, B., Sporbert, A., Lorenzen, T., Meyer, A.M., Herlan, L., Witten, A., Rühle, F., Zhou, W., de Heer, E., Scharpfenecker, M., Panáková, D., Stoll, M. and Kreutz, R.
eLife 8
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22 March 2019
Extensive transmission of microbes along the gastrointestinal tract.
Schmidt, T.S.B., Hayward, M.R., Coelho, L.P., Li, S.S., Costea, P.I., Voigt, A.Y., Wirbel, J., Maistrenko, O.M., Alves, R.J.C., Bergsten, E., de Beaufort, C., Sobhani, I., Heintz-Buschart, A., Sunagawa, S., Zeller, G., Wilmes, P. and Bork, P.
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WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids.
Yoney, A., Etoc, F., Ruzo, A., Carroll, T., Metzger, J.J., Martyn, I., Li, S., Kirst, C., Siggia, E.D. and Brivanlou, A.H.
eLife 7
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13 November 2018
Chromatin accessibility dynamics across C. elegans development and ageing.
Jänes, J., Dong, Y., Schoof, M., Serizay, J., Appert, A., Cerrato, C., Woodbury, C., Chen, R., Gemma, C., Huang, N., Kissiov, D., Stempor, P., Steward, A., Zeiser, E., Sauer, S. and Ahringer, J.
eLife 7
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26 October 2018
New insights into the cellular temporal response to proteostatic stress.
Rendleman, J., Cheng, Z., Maity, S., Kastelic, N., Munschauer, M., Allgoewer, K., Teo, G., Zhang, Y.B.M., Lei, A., Parker, B., Landthaler, M., Freeberg, L., Kuersten, S., Choi, H. and Vogel, C.
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12 October 2018
The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.
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9 October 2018
Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease.
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4 September 2018
Human axial progenitors generate trunk neural crest cells in vitro.
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Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity.
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13 April 2018
Multi-view light-sheet imaging and tracking with the MaMuT software reveals the cell lineage of a direct developing arthropod limb.
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NOTCH activity differentially affects alternative cell fate acquisition and maintenance.
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26 March 2018
Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning.
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7 February 2018
YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development.
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Cell-accurate optical mapping across the entire developing heart.
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A synthetic biology approach to probing nucleosome symmetry.
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Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin.
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20 June 2017
Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts.
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3 June 2017
Loss of Ptpn11 (Shp2) drives satellite cells into quiescence.
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2 May 2017
Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes.
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Domain-swapped T cell receptors improve the safety of TCR gene therapy.
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8 November 2016
Loss of MeCP2 disrupts cell autonomous and autocrine BDNF signaling in mouse glutamatergic neurons.
Sampathkumar, C., Wu, Y.J., Vadhvani, M., Trimbuch, T., Eickholt, B. and Rosenmund, C.
eLife 5
: e19374.
26 October 2016
Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice.
Carmona, R., Canete, A., Cano, E., Ariza, L., Rojas, A. and Munoz-Chapuli, R.
eLife 5
: e16009.
19 September 2016
Increasing Notch signaling antagonizes PRC2-mediated silencing to promote reprograming of germ cells into neurons.
Seelk, S., Adrian-Kalchhauser, I., Hargitai, B., Hajduskova, M., Gutnik, S., Tursun, B. and Ciosk, R.
eLife 5
: e15477.
7 September 2016
Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis.
Esteves de Lima, J., Bonnin, M.A., Birchmeier, C. and Duprez, D.
eLife 5
: e15593.
24 August 2016
Conserved functional antagonism of CELF 1 and MBNL proteins controls stem cell-specific alternative splicing in planarians.
Solana, J., Irimia, M., Ayoub, S., Orejuela, M.R., Zywitza, V., Jens, M., Tapial, J., Ray, D., Morris, Q.D., Hughes, T.R., Blencowe, B.J. and Rajewsky, N.
eLife 5
: e16797.
9 August 2016
Different promoter affinities account for specificity in MYC-dependent gene regulation.
Lorenzin, F., Benary, U., Baluapuri, A., Walz, S., Jung, L.A., von Eyss, B., Kisker, C., Wolf, J., Eilers, M. and Wolf, E.
eLife 5
: e15161.
27 July 2016
Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit.
Hatzold, J., Beleggia, F., Herzig, H., Altmüller, J., Nürnberg, P., Bloch, W., Wollnik, B. and Hammerschmidt, M.
eLife 5
: e14277.
15 July 2016
Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration.
Barrionuevo, F.J., Hurtado, A., Kim, G.J., Real, F.M., Bakkali, M., Kopp, J.L., Sander, M., Scherer, G., Burgos, M. and Jiménez, R.
eLife 5
: e15635.
21 June 2016
Cell-specific synaptic plasticity induced by network oscillations.
Zarnadze, S., Bäuerle, P., Santos-Torres, J., Böhm, C., Schmitz, D., Geiger, J.R.P., Dugladze, T. and Gloveli, T.
eLife 5
: e14912.
24 May 2016
Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion.
Ubezio, B., Blanco, R.A., Geudens, I., Stanchi, F., Mathivet, T., Jones, M.L., Ragab, A., Bentley, K. and Gerhardt, H.
eLife 5
: e12167.
13 April 2016
The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.
Kabat, A.M., Harrison, O.J., Riffelmacher, T., Moghaddam, A.E., Pearson, C.F., Laing, A., Abeler-Dörner, L., Forman, S.P., Grencis, R.K., Sattentau, Q., Simon, A.K., Pott, J. and Maloy, K.J.
eLife 5
: e12444.
11 March 2016
Temporal modulation of collective cell behavior controls vascular network topology.
Kur, E., Kim, J., Tata, A., Comin, C.H., Harrington, K.I., Costa, L.d.F., Bentley, K. and Gu, C.
eLife 5
: e13212.
24 February 2016
Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling.
Franco, C.A., Jones, M.L., Bernabeu, M.O., Vion, A.C., Barbacena, P., Fan, J., Mathivet, T., Fonseca, C.G., Ragab, A., Yamaguchi, T.P., Coveney, P.V., Lang, R.A. and Gerhardt, H.
eLife 5
: e07727.
4 February 2016
2015
Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells.
Dias, J.D., Rito, T., Torlai Triglia, E., Kukalev, A., Ferrai, C., Chotalia, M., Brookes, E., Kimura, H. and Pombo, A.
eLife 4
: e11215.
19 December 2015
An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence.
Frahm, S., Antolin-Fontes, B., Goerlich, A., Zander, J.F., Ahnert-Hilger, G. and Ibanez-Tallon, I.
eLife 4
: e11396.
1 December 2015
Genomic DNA transposition induced by human PGBD5.
Henssen, A.G., Henaff, E., Jiang, E., Eisenberg, A.R., Carson, J.R., Villasante, C.M., Ray, M., Still, E., Burns, M., Gandara, J., Feschotte, C., Mason, C.E. and Kentsis, A.
eLife 4
: e10565.
25 September 2015
CO(2) in the spotlight.
Hernandez-Miranda, L.R. and Birchmeier, C.
eLife 4
: e08086.
13 May 2015
2014
Drep-2 is a novel synaptic protein important for learning and memory.
Andlauer, T.F.M., Scholz-Kornehl, S., Tian, R., Kirchner, M., Babikir, H.A., Depner, H., Loll, B., Quentin, C., Gupta, V.K., Holt, M.G., Dipt, S., Cressy, M., Wahl, M.C., Fiala, A., Selbach, M., Schwärzel, M. and Sigrist, S.J.
eLife 3
: e03895.
13 November 2014
Autophagy is a critical regulator of memory CD8(+) T cell formation.
Puleston, D.J., Zhang, H., Powell, T.J., Lipina, E., Sims, S., Panse, I., Watson, A.S., Cerundolo, V., Townsend, A.R., Klenerman, P. and Simon, A.K.
eLife 3
: e03706.
11 November 2014
2013
A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control.
Bartha, I., Carlson, J.M., Brumme, C.J., McLaren, P.J., Brumme, Z.L., John, M., Haas, D.W., Martinez-Picado, J., Dalmau, J., López-Galíndez, C., Casado, C., Rauch, A., Günthard, H.F., Bernasconi, E., Vernazza, P., Klimkait, T., Yerly, S., O'Brien, S.J., Listgarten, J., Pfeifer, N., Lippert, C., Fusi, N., Kutalik, Z., Allen, T.M., Müller, V., Harrigan, P.R., Heckerman, D., Telenti, A. and Fellay, J.
eLife 2
: e01123.
29 October 2013
In situ structural analysis of the Yersinia enterocolitica injectisome.
Kudryashev, M., Stenta, M., Schmelz, S., Amstutz, M., Wiesand, U., Castaño-Díez, D., Degiacomi, M.T., Münnich, S., Bleck, C.K., Kowal, J., Diepold, A., Heinz, D.W., Dal Peraro, M., Cornelis, G.R. and Stahlberg, H.
eLife 2
: e00792.
30 July 2013
This list was generated on Thu Dec 26 19:45:22 2024 UTC.