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A new human embryonic cell type associated with activity of young transposable elements allows definition of the inner cell mass.
Singh, M. and Kondrashkina, A. and Widmann, T.J. and Cortes, J.L. and Bansal, V. and Wang, J. and Römer, C. and Garcia-Canadas, M. and Garcia-Perez, J.L. and Hurst, L.D. and Izsvak, Z.
PLoS Biology 21 (6): e3002162. 20 June 2023


The synaptic scaffold protein MPP2 interacts with GABA(A) receptors at the periphery of the postsynaptic density of glutamatergic synapses.
Schmerl, B. and Gimber, N. and Kuropka, B. and Stumpf, A. and Rentsch, J. and Kunde, S.A. and von Sivers, J. and Ewers, H. and Schmitz, D. and Freund, C. and Schmoranzer, J. and Rademacher, N. and Shoichet, S.A.
PLoS Biology 20 (3): e3001503. 21 March 2022


Recruitment of release sites underlies chemical presynaptic potentiation at hippocampal mossy fiber boutons.
Orlando, M. and Dvorzhak, A. and Bruentgens, F. and Maglione, M. and Rost, B.R. and Sigrist, S.J. and Breustedt, J. and Schmitz, D.
PLoS Biology 19 (6): e3001149. 21 June 2021


NCX1 represents an ionic Na(+) sensing mechanism in macrophages.
Neubert, P. and Homann, A. and Wendelborn, D. and Bär, A.L. and Krampert, L. and Trum, M. and Schröder, A. and Ebner, S. and Weichselbaum, A. and Schatz, V. and Linz, P. and Veelken, R. and Schulte-Schrepping, J. and Aschenbrenner, A.C. and Quast, T. and Kurts, C. and Geisberger, S. and Kunzelmann, K. and Hammer, K. and Binger, K.J. and Titze, J. and Müller, D.N. and Kolanus, W. and Schultze, J.L. and Wagner, S. and Jantsch, J.
PLoS Biology 18 (6): e3000722. 22 June 2020


Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein.
Birol, M. and Wojcik, S.P. and Miranker, A.D. and Rhoades, E.
PLoS Biology 17 (6): e3000318. 18 June 2019


The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.
El-Athman, R. and Genov, N.N. and Mazuch, J. and Zhang, K. and Yu, Y. and Fuhr, L. and Abreu, M. and Li, Y. and Wallach, T. and Kramer, A. and Schmitt, C.A. and Relógio, A.
PLoS Biology 15 (12): e2002940. 7 December 2017

Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1.
Juneja, M. and Kobelt, D. and Walther, W. and Voss, C. and Smith, J. and Specker, E. and Neuenschwander, M. and Gohlke, B.O. and Dahlmann, M. and Radetzki, S. and Preissner, R. and von Kries, J.P. and Schlag, P.M. and Stein, U.
PLoS Biology 15 (6): e2000784. 1 June 2017


Ryanodine receptor activation induces long-term plasticity of spine calcium dynamics.
Johenning, F.W. and Theis, A.K. and Pannasch, U. and Rückl, M. and Rüdiger, S. and Schmitz, D.
PLoS Biology 13 (6): e1002181. 22 June 2015

Dynamic endothelial cell rearrangements drive developmental vessel regression.
Franco, C.A. and Jones, M.L. and Bernabeu, M.O. and Geudens, I. and Mathivet, T. and Rosa, A. and Lopes, F.M. and Lima, A.P. and Ragab, A. and Collins, R.T. and Phng, L.K. and Coveney, P.V. and Gerhardt, H.
PLoS Biology 13 (4): e1002125. 17 April 2015

Composition, formation, and regulation of the cytosolic c-ring, a dynamic component of the type III secretion injectisome.
Diepold, A. and Kudryashev, M. and Delalez, N.J. and Berry, R.M. and Armitage, J.P.
PLoS Biology 13 (1): e1002039. 15 January 2015


In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity.
Gouti, M. and Tsakiridis, A. and Wymeersch, F.J. and Huang, Y. and Kleinjung, J. and Wilson, V. and Briscoe, J.
PLoS Biology 12 (8): e1001937. 26 August 2014

Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses.
Dejanovic, B. and Semtner, M. and Ebert, S. and Lamkemeyer, T. and Neuser, F. and Luescher, B. and Meier, J.C. and Schwarz, G.
PLoS Biology 12 (7): e1001908. 15 July 2014


HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration.
Mielcarek, M. and Landles, C. and Weiss, A. and Bradaia, A. and Seredenina, T. and Inuabasi, L. and Osborne, G.F. and Wadel, K. and Touller, C. and Butler, R. and Robertson, J. and Franklin, S.A. and Smith, D.L. and Park, L. and Marks, P.A. and Wanker, E.E. and Olson, E.N. and Luthi-Carter, R. and van der Putten, H. and Beaumont, V. and Bates, G.P.
PLoS Biology 11 (11): e1001717. November 2013


A genetic basis for mechanosensory traits in humans.
Frenzel, H. and Bohlender, J. and Pinsker, K. and Wohlleben, B. and Tank, J. and Lechner, S.G. and Schiska, D. and Jaijo, T. and Rueschendorf, F. and Saar, K. and Jordan, J. and Millan, J.M. and Gross, M. and Lewin, G.R.
PLoS Biology 10 (5): e1001318. 1 May 2012

Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity.
Luo, C. and Gangadharan, V. and Bali, K.K. and Xie, R.G. and Agarwal, N. and Kurejova, M. and Tappe-Theodor, A. and Tegeder, I. and Feil, S. and Lewin, G. and Polgar, E. and Todd, A.J. and Schlossmann, J. and Hofmann, F. and Liu, D.L. and Hu, S.J. and Feil, R. and Kuner, T. and Kuner, R.
PLoS Biology 10 (3): e1001283. 13 March 2012


MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates.
Somel, M. and Liu, X. and Tang, L. and Yan, Z. and Hu, H. and Guo, S. and Jiang, X. and Zhang, X. and Xu, G. and Xie, G. and Li, N. and Hu, Y. and Chen, W. and Paeaebo, S. and Khaitovich, P.
PLoS Biology 9 (12): e1001214. December 2011


Structure of a classical MHC class I molecule that binds "non-classical" ligands.
Hee, C.S. and Gao, S. and Loll, B. and Miller, M.M. and Uchanska-Ziegler, B. and Daumke, O. and Ziegler, A.
PLoS Biology 8 (12): e1000557. 7 December 2010

An integrated micro- and macroarchitectural analysis of the drosophila brain by computer-assisted serial section electron microscopy.
Cardona, A. and Saalfeld, S. and Preibisch, S. and Schmid, B. and Cheng, A. and Pulokas, J. and Tomancak, P. and Hartenstein, V.
PLoS Biology 8 (10): e1000502. 5 October 2010

Ontologies in quantitative biology: a basis for comparison, integration, and discovery.
Jensen, L.J. and Bork, P.
PLoS Biology 8 (5): e1000374. 25 May 2010

Poised transcription factories prime silent uPA gene prior to activation.
Ferrai, C. and Xie, S.Q. and Luraghi, P. and Munari, D. and Ramirez, F. and Branco, M.R. and Pombo, A. and Crippa, M.P.
PLoS Biology 8 (1): e1000270. 5 January 2010


Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation.
Paulmann, N. and Grohmann, M. and Voigt, J.P. and Bert, B. and Vowinckel, J. and Bader, M. and Skelin, M. and Jevsek, M. and Fink, H. and Rupnik, M. and Walther, D.J.
PLoS Biology 7 (10): e1000229. 27 October 2009


Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber).
Park, T.J. and Lu, Y. and Jüttner, R. and Smith, E.S.J. and Hu, J. and Brand, A. and Wetzel, C. and Milenkovic, N. and Erdmann, B. and Heppenstall, P.A. and Laurito, C.E. and Wilson, S.P. and Lewin, G.R.
PLoS Biology 6 (1): e13. 29 January 2008


Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis.
Soederhaell, C. and Marenholz, I. and Kerscher, T. and Rueschendorf, F. and Esparza-Gordillo, J. and Worm, M. and Gruber, C. and Mayr, G. and Albrecht, M. and Rohde, K. and Schulz, H. and Wahn, U. and Huebner, N. and Lee, Y.A.
PLoS Biology 5 (9): e242. September 2007


Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations.
Branco, M.R. and Pombo, A.
PLoS Biology 4 (5): e138. May 2006


Systematic association of genes to phenotypes by genome and literature mining.
Korbel, J.O. and Doerks, T. and Jensen, L.J. and Perez-Iratxeta, C. and Kaczanowski, S. and Hooper, S.D. and Andrade, M.A. and Bork, P.
PLoS Biology 3 (5): e134. 5 April 2005


Transcriptional control in the segmentation gene network of Drosophila.
Schroeder, M.D. and Pearce, M. and Fak, J. and Fan, H. and Unnerstall, U. and Emberly, E. and Rajewsky, N. and Siggia, E.D. and Gaul, U.
PLoS Biology 2 (9): E271. September 2004

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