Browse by Research Team

2024

MarShie: a clearing protocol for 3D analysis of single cells throughout the bone marrow at subcellular resolution.
Mertens, T.F. and Liebheit, A.T. and Ehl, J. and Köhler, R. and Rakhymzhan, A. and Woehler, A. and Katthän, L. and Ebel, G. and Liublin, W. and Kasapi, A. and Triantafyllopoulou, A. and Schulz, T.J. and Niesner, R.A. and Hauser, A.E.
Nature Communications 15 (1): 1764. 26 February 2024

2023

Spatiotemporal, optogenetic control of gene expression in organoids.
Legnini, I. and Emmenegger, L. and Zappulo, A. and Rybak-Wolf, A. and Wurmus, R. and Oliveras Martinez, A. and Cerda Jara, C. and Boltengagen, A. and Hessler, T. and Mastrobuoni, G. and Kempa, S. and Zinzen, R. and Woehler, A. and Rajewsky, N.
Nature Methods 20 (10): 1544-1552. October 2023

Prox2 and Runx3 vagal sensory neurons regulate esophageal motility.
Lowenstein, E.D. and Ruffault, P.L. and Misios, A. and Osman, K.L. and Li, H. and Greenberg, R.S. and Thompson, R. and Song, K. and Dietrich, S. and Li, X. and Vladimirov, N. and Woehler, A. and Brunet, J.F. and Zampieri, N. and Kühn, R. and Liberles, S.D. and Jia, S. and Lewin, G.R. and Rajewsky, N. and Lever, T.E. and Birchmeier, C.
Neuron 111 (14): 2184-2200.e7. 19 July 2023

Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids.
Rybak-Wolf, A. and Wyler, E. and Pentimalli, T.M. and Legnini, I. and Oliveras Martinez, A. and Glažar, P. and Loewa, A. and Kim, S.J. and Kaufer, B.B. and Woehler, A. and Landthaler, M. and Rajewsky, N.
Nature Microbiology 8 (7): 1252-1266. July 2023

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.
Lin, M. and Hartl, K. and Heuberger, J. and Beccaceci, G. and Berger, H. and Li, H. and Liu, L. and Müllerke, S. and Conrad, T. and Heymann, F. and Woehler, A. and Tacke, F. and Rajewsky, N. and Sigal, M.
Nature Communications 14 (1): 3025. 25 May 2023

A hydraulic feedback loop between mesendoderm cell migration and interstitial fluid relocalization promotes embryonic axis formation in zebrafish.
Huljev, K. and Shamipour, S. and Pinheiro, D. and Preusser, F. and Steccari, I. and Sommer, C.M. and Naik, S. and Heisenberg, C.P.
Developmental Cell 58 (7): 582-596.e7. 10 April 2023

2022

RS-FISH: precise, interactive, fast, and scalable FISH spot detection.
Bahry, E. and Breimann, L. and Zouinkhi, M. and Epstein, L. and Kolyvanov, K. and Mamrak, N. and King, B. and Long, Xi and Harrington, K.I.S. and Lionnet, T. and Preibisch, S.
Nature Methods 19 (12): 1563-1567. December 2022

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies.
Reichart, D. and Lindberg, E.L. and Maatz, H. and Miranda, A.M.A. and Viveiros, A. and Shvetsov, N. and Gärtner, A. and Nadelmann, E.R. and Lee, M. and Kanemaru, K. and Ruiz-Orera, J. and Strohmenger, V. and DeLaughter, D.M. and Patone, G. and Zhang, H. and Woehler, A. and Lippert, C. and Kim, Y. and Adami, E. and Gorham, J.M. and Barnett, S.N. and Brown, K. and Buchan, R.J. and Chowdhury, R.A. and Constantinou, C. and Cranley, J. and Felkin, L.E. and Fox, H. and Ghauri, A. and Gummert, J. and Kanda, M. and Li, R. and Mach, L. and McDonough, B. and Samari, S. and Shahriaran, F. and Yapp, C. and Stanasiuk, C. and Theotokis, P.I. and Theis, F.J. and van den Bogaerdt, A. and Wakimoto, H. and Ware, J.S. and Worth, C.L. and Barton, P.J.R. and Lee, Y.A. and Teichmann, S.A. and Milting, H. and Noseda, M. and Oudit, G.Y. and Heinig, M. and Seidman, J.G. and Hubner, N. and Seidman, C.E.
Science 377 (6606): eabo1984. 5 August 2022

Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice.
Schepanski, S. and Chini, M. and Sternemann, V. and Urbschat, C. and Thiele, K. and Sun, T. and Zhao, Y. and Poburski, M. and Woestemeier, A. and Thieme, M.T. and Zazara, D.E. and Alawi, M. and Fischer, N. and Heeren, J. and Vladimirov, N. and Woehler, A. and Puelles, V.G. and Bonn, S. and Gagliani, N. and Hanganu-Opatz, I.L. and Arck, P.C.
Nature Communications 13 (1): 4571. 5 August 2022

Long-term imaging reveals behavioral plasticity during C. elegans dauer exit.
Preusser, F. and Neuschulz, A. and Junker, J.P. and Rajewsky, N. and Preibisch, S.
bioRxiv : 2022.04.25.489360v1. 26 April 2022

Spatio-temporal, optogenetic control of gene expression in organoids.
Legnini, I. and Emmenegger, L. and Zappulo, A. and Wurmus, R. and Oliveras Martinez, A. and Cerda Jara, C. and Boltengagen, A. and Hessler, T. and Mastrobuoni, G. and Rybak-Wolf, A. and Kempa, S. and Zinzen, R.P. and Woehler, A. and Rajewsky, N.
bioRxiv : 2021.09.26.461850v3. 9 February 2022

The histone H4 lysine 20 demethylase DPY-21 regulates the dynamics of condensin DC binding.
Breimann, L. and Morao, A.K. and Kim, J. and Jimenez, D.S. and Maryn, N. and Bikkasani, K. and Carrozza, M.J. and Albritton, S.E. and Kramer, M. and Street, L.A. and Cerimi, K. and Schumann, V.F. and Bahry, E. and Preibisch, S. and Woehler, A. and Ercan, S.
Journal of Cell Science 135 (2): jcs258818. January 2022

2021

The H4K20 demethylase DPY-21 regulates the dynamics of condensin DC binding.
Breimann, L. and Morao, A.K. and Kim, J. and Jimenez, D. and Maryn, N. and Bikkasani, K. and Carrozza, M.J. and Albritton, S.E. and Kramer, M. and Street, L.A. and Cerimi, K. and Schumann, V.F. and Bahry, E. and Preibisch, S. and Woehler, A. and Ercan, S.
bioRxiv : 2021.04.11.438056. 24 September 2021

Dual-view light-sheet imaging through a tilted glass interface using a deformable mirror.
Vladimirov, N. and Preusser, F. and Wisniewski, J. and Yaniv, Z. and Desai, R.A. and Woehler, A. and Preibisch, S.
Biomedical Optics Express 12 (4): 2186-2203. 1 April 2021

Neurodegeneration in human brain organoids infected with herpes simplex virus type 1.
Rybak-Wolf, A. and Wyler, E. and Legnini, I. and Loewa, A. and Glažar, P. and Kim, S.J. and Pentimalli, T.M. and Oliveras Martinez, A. and Beyersdorf, B. and Woehler, A. and Landthaler, M. and Rajewsky, N.
bioRxiv : 2021.03.05.434122. 7 March 2021

Single synapse glutamate imaging reveals multiple levels of release mode regulation in mammalian synapses.
Farsi, Z. and Walde, M. and Klementowicz, A.E. and Paraskevopoulou, F. and Woehler, A.
iScience 24 (1): 101909. 22 January 2021

2020

Dual-view light-sheet imaging through tilted glass interface using a deformable mirror.
Vladimirov, N. and Preusser, F. and Wisniewski, J. and Yaniv, Z. and Desai, R.A. and Woehler, A. and Preibisch, S.
bioRxiv : 2020.10.20.345306. 21 October 2020

Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.
Weinert, S. and Gimber, N. and Deuschel, D. and Stuhlmann, T. and Puchkov, D. and Farsi, Z. and Ludwig, C.F. and Novarino, G. and López-Cayuqueo, K.I. and Planells-Cases, R. and Jentsch, T.J.
EMBO Journal 39 (9): e103358. 4 May 2020

2019

Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.
Chaimowicz, C. and Ruffault, P.L. and Chéret, C. and Woehler, A. and Zampieri, N. and Fortin, G. and Garratt, A.N. and Birchmeier, C.
Development 146 (17): dev174045. 6 September 2019

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C. and Rom, A. and Franke, V. and Imami, K. and Arrey, G. and Terne, M. and Woehler, A. and Akalin, A. and Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

2018

Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity.
Farsi, Z. and Gowrisankaran, S. and Krunic, M. and Rammner, B. and Woehler, A. and Lafer, E.M. and Mim, C. and Jahn, R. and Milosevic, I.
eLife 7 : e32569. 13 April 2018

2017

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A. and van den Bruck, D. and Ciolli Mattioli, C. and Franke, V. and Imami, K. and McShane, E. and Moreno-Estelles, M. and Calviello, L. and Filipchyk, A. and Peguero-Sanchez, E. and Müller, T. and Woehler, A. and Birchmeier, C. and Merino, E. and Rajewsky, N. and Ohler, U. and Mazzoni, E.O. and Selbach, M. and Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Proton electrochemical gradient: driving and regulating neurotransmitter uptake.
Farsi, Z. and Jahn, R. and Woehler, A.
BioEssays 39 (5): 1600240. May 2017

Engineering an achromatic Bessel beam using a phase-only spatial light modulator and an iterative Fourier transformation algorithm.
Walde, M. and Jost, A. and Wicker, K. and Heintzmann, R.
Optics Communications 383 : 64-68. 15 January 2017

Imaging activity-dependent signaling dynamics at the neuronal synapse using FRET-based biosensors.
Farsi, Z. and Woehler, A.
Methods in Molecular Biology 1538 : 261-275. 2017

2016

Superpriming of synaptic vesicles as a common basis for intersynapse variability and modulation of synaptic strength.
Taschenberger, H. and Woehler, A. and Neher, E.
Proceedings of the National Academy of Sciences of the United States of America 113 (31): E4548-E4557. 2 August 2016

Single-vesicle imaging reveals different transport mechanisms between glutamatergic and GABAergic vesicles.
Farsi, Z. and Preobraschenski, J. and van den Bogaart, G. and Riedel, D. and Jahn, R. and Woehler, A.
Science 351 (6276): 981-984. 26 February 2016

2015

The Green Gut: chlorophyll degradation in the gut of Spodoptera littoralis.
Badgaa, A. and Büchler, R. and Wielsch, N. and Walde, M. and Heintzmann, R. and Pauchet, Y. and Svatos, A. and Ploss, K. and Boland, W.
Journal of Chemical Ecology 41 (11): 965-974. November 2015

2014

Calcium-buffering effects of gluconate and nucleotides, as determined by a novel fluorimetric titration method.
Woehler, A. and Lin, K.H. and Neher, E.
Journal of Physiology 592 (22): 4863-4875. 15 November 2014

Vinculin binding angle in podosomes revealed by high resolution microscopy.
Walde, M. and Monypenny, J. and Heintzmann, R. and Jones, G.E. and Cox, S.
PLoS ONE 9 (2): e88251. 11 February 2014

2013

Blocking endocytosis enhances short-term synaptic depression under conditions of normal availability of vesicles.
Hua, Y. and Woehler, A. and Kahms, M. and Haucke, V. and Neher, E. and Klingauf, J.
Neuron 80 (2): 343-349. 16 October 2013

Functional analysis of PEX13 mutation in a Zellweger syndrome spectrum patient reveals novel homooligomerization of PEX13 and its role in human peroxisome biogenesis.
Krause, C. and Rosewich, H. and Woehler, A. and Gärtner, J.
Human Molecular Genetics 22 (19): 3844-3857. 1 October 2013

Simultaneous quantitative live cell imaging of multiple FRET-based biosensors.
Woehler, A.
PLoS ONE 8 (4): e61096. 16 April 2013

2012

Quantitative intensity-based FRET approaches - a comparative snapshot.
Zeug, A. and Woehler, A. and Neher, E. and Ponimaskin, E.
Biophysical Journal 103 (9): 1821-1827. 7 November 2012

Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking.
Renner, U. and Zeug, A. and Woehler, A. and Niebert, M. and Dityatev, A. and Dityateva, G. and Gorinski, N. and Guseva, D. and Abdel-Galil, D. and Froehlich, M. and Doering, F. and Wischmeyer, E. and Richter, D.W. and Neher, E. and Ponimaskin, E.G.
Journal of Cell Science 125 (Pt 10): 2486-2499. 15 May 2012

2010

Signal/noise analysis of FRET-based sensors.
Woehler, A. and Wlodarczyk, J. and Neher, E.
Biophysical Journal 99 (7): 2344-2354. 6 October 2010

2009

G protein - mediated signaling: same receptor, multiple effectors.
Woehler, A. and Ponimaskin, E.G.
Current Molecular Pharmacology 2 (3): 237-248. November 2009

Specific oligomerization of the 5-HT1A receptor in the plasma membrane.
Woehler, A. and Wlodarczyk, J. and Ponimaskin, E.G.
Glycoconjugate Journal 26 (6): 749-756. August 2009

2008

Stimulation- and palmitoylation-dependent changes in oligomeric conformation of serotonin 5-HT1A receptors.
Kobe, F. and Renner, U. and Woehler, A. and Wlodarczyk, J. and Papusheva, E. and Bao, G. and Zeug, A. and Richter, D. and Neher, E. and Ponimaskin, E.
Biochimica et Biophysica Acta - Molecular Cell Research 1783 (8): 1503-1516. August 2008

Analysis of FRET signals in the presence of free donors and acceptors.
Wlodarczyk, J. and Woehler, A. and Kobe, F. and Ponimaskin, E. and Zeug, A. and Neher, E.
Biophysical Journal 94 (3): 986-1000. 1 February 2008