Browse by Research Team

2014

Progesterone supplementation attenuates hypertension and the autoantibody to the angiotensin II type I receptor in response to elevated interleukin-6 during pregnancy.
Amaral, L.M. and Kipprono, L. and Cornelius, D.C. and Shoemaker, C. and Wallace, K. and Moseley, J. and Wallukat, G. and Martin, J.N. and Dechend, R. and Lamarca, B.
American Journal of Obstetrics and Gynecology 211 (2): 158.e1-158.e6. August 2014

2013

The patent situation concerning the treatment of diseases associated with autoantibodies directed against G-protein-coupled receptors.
Haberland, A. and Wallukat, G. and Schimke, I.
Pharmaceutical Patent Analyst 2 (2): 231-248. March 2013

Immunoadsorption therapy for dilated cardiomyopathy and pulmonary arterial hypertension.
Dandel, M. and Wallukat, G. and Englert, A. and Hetzer, R.
Atherosclerosis Supplements 14 (1): 203-211. January 2013

2012

Long-term benefits of immunoadsorption in beta(1)-adrenoceptor autoantibody-positive transplant candidates with dilated cardiomyopathy.
Dandel, M. and Wallukat, G. and Englert, A. and Lehmkuhl, H.B. and Knosalla, C. and Hetzer, R.
European Journal of Heart Failure 14 (12): 1374-1388. December 2012

Chemical composition and biological activity of Paris quadrifolia L.
Jenett-Siems, K. and Krause, N. and Siems, K. and Jakupovic, S. and Wallukat, G. and Melzig, M.F.
Zeitschrift fuer Naturforschung C 67 (11-12): 565-570. November 2012

The first aptamer-apheresis column specifically for clearing blood of beta1-receptor autoantibodies : a successful proof of principle using autoantibody-positive SHR rats.
Wallukat, G. and Haberland, A. and Berg, S. and Schulz, A. and Freyse, E.J. and Dahmen, C. and Kage, A. and Dandel, M. and Vetter, R. and Salzsieder, E. and Kreutz, R. and Schimke, I.
Circulation Journal 76 (10): 2449-2455. 25 September 2012

IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy.
Dhillion, P. and Wallace, K. and Herse, F. and Scott, J. and Wallukat, G. and Heath, J. and Mosely, J. and Martin, J.N. and Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 303 (4): R353-R358. 15 August 2012

Anti-β-adrenoceptors autoimmunity causing 'idiopathic' arrhythmias and cardiomyopathy.
Brisinda, D. and Sorbo, A.R. and Venuti, A. and Ruggieri, M.P. and Manna, R. and Fenici, P. and Wallukat, G. and Hoebeke, J. and Frustaci, A. and Fenici, R.
Circulation Journal 76 (6): 1345-1353. 25 May 2012

Role of β(1)-adrenoceptor autoantibodies in the pathogenesis of dilated cardiomyopathy.
Dandel, M. and Wallukat, G. and Potapov, E. and Hetzer, R.
Immunobiology 217 (5): 511-520. May 2012

2011

Autoimmunity against the beta(2) adrenergic receptor and muscarinic-2 receptor in complex regional pain syndrome.
Kohr, D. and Singh, P. and Tschernatsch, M. and Kaps, M. and Pouokam, E. and Diener, M. and Kummer, W. and Birklein, F. and Vincent, A. and Goebel, A. and Wallukat, G. and Blaes, F.
Pain 152 (12): 2690-2700. December 2011

Hypertension in response to IL-6 during pregnancy: role of AT1-receptor activation.
Lamarca, B. and Speed, J. and Ray, L.F. and Cockrell, K. and Wallukat, G. and Dechend, R. and Granger, J.
International Journal of Interferon, Cytokine and Mediator Research 2011 (3): 65-70. 3 November 2011

Aptamer neutralization of beta1-adrenoceptor autoantibodies isolated from patients with cardiomyopathies.
Haberland, A. and Wallukat, G. and Dahmen, C. and Kage, A. and Schimke, I.
Circulation Research 109 (9): 986-992. 14 October 2011

Aptamer binding and neutralization of beta(1)-adrenoceptor autoantibodies: basics and a vision of its future in cardiomyopathy treatment.
Haberland, A. and Wallukat, G. and Schimke, I.
Trends in Cardiovascular Medicine 21 (6): 177-182. August 2011

Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant rats.
Wenzel, K. and Rajakumar, A. and Haase, H. and Geusens, N. and Hubner, N. and Schulz, H. and Brewer, J. and Roberts, L. and Hubel, C.A. and Herse, F. and Hering, L. and Qadri, F. and Lindschau, C. and Wallukat, G. and Pijnenborg, R. and Heidecke, H. and Riemekasten, G. and Luft, F.C. and Muller, D.N. and Lamarca, B. and Dechend, R.
Hypertension 58 (1): 77-84. July 2011

Hypertension in response to AT1-AA: role of reactive oxygen species in pregnancy-induced hypertension.
Parrish, M.R. and Wallace, K. and Tam Tam, K.B. and Herse, F. and Weimer, A. and Wenzel, K. and Wallukat, G. and Ray, L.F. and Arany, M. and Cockrell, K. and Martin, J.N. and Dechend, R. and Lamarca, B.
American Journal of Hypertension 24 (7): 835-840. July 2011

17(R),18(S)-epoxyeicosatetraenoic acid, a potent eicosapentaenoic acid (EPA) derived regulator of cardiomyocyte contraction: structure-activity relationships and stable analogues.
Falck, J.R. and Wallukat, G. and Puli, N. and Goli, M. and Arnold, C. and Konkel, A. and Rothe, M. and Fischer, R. and Mueller, D.N. and Schunck, W.H.
Journal of Medicinal Chemistry 54 (12): 4109-4118. 23 June 2011

Cardiac troponin T measured with a highly sensitive assay for diagnosis and monitoring of heart injury in chronic chagas disease.
Munoz Saravia, S.G. and Haberland, A. and Bartel, S. and Araujo, R. and Valda, G. and Duchen Reynaga, D. and Diaz Ramirez, I. and Borges, A.C. and Wallukat, G. and Schimke, I.
Archives of Pathology & Laboratory Medicine 135 (2): 243-248. February 2011

2010

Effects of circulating and local uteroplacental angiotensin II in rat pregnancy.
Hering, L. and Herse, F. and Geusens, N. and Verlohren, S. and Wenzel, K. and Staff, A.C. and Brosnihan, K.B. and Huppertz, B. and Luft, F.C. and Mueller, D.N. and Pijnenborg, R. and Cartwright, J.E. and Dechend, R.
Hypertension 56 (2): 311-318. August 2010

The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancy.
Parrish, M.R. and Murphy, S.R. and Rutland, S. and Wallace, K. and Wenzel, K. and Wallukat, G. and Keiser, S. and Ray, L.F. and Dechend, R. and Martin, J.N. and Granger, J.P. and Lamarca, B.
American Journal of Hypertension 23 (8): 911-916. August 2010

alpha(1A)-adrenergic receptor-directed autoimmunity induces left ventricular damage and diastolic dysfunction in rats.
Wenzel, K. and Wallukat, G. and Qadri, F. and Huebner, N. and Schulz, H. and Hummel, O. and Herse, F. and Heuser, A. and Fischer, R. and Heidecke, H. and Luft, F.C. and Mueller, D.N. and Dietz, R. and Dechend, R.
PLoS ONE 5 (2): e9409. 24 February 2010

Cellular uptake and biological activity of peptide nucleic acids conjugated with peptides with and without cell-penetrating ability.
Turner, Y. and Wallukat, G. and Saeaelik, P. and Wiesner, B. and Pritz, S. and Oehlke, J.
Journal of Peptide Science 16 (1): 71-80. January 2010

2009

Prevalence of agonistic autoantibodies against the angiotensin II type 1 receptor and soluble fms-like tyrosine kinase 1 in a gestational age-matched case study.
Herse, F. and Verlohren, S. and Wenzel, K. and Pape, J. and Mueller, D.N. and Modrow, S. and Wallukat, G. and Luft, F.C. and Redman, C.W. and Dechend, R.
Hypertension 53 (2): 393-398. February 2009

2008

Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertension.
Wenzel, K. and Haase, H. and Wallukat, G. and Derer, W. and Bartel, S. and Homuth, V. and Herse, F. and Huebner, N. and Schulz, H. and Janczikowski, M. and Lindschau, C. and Schroeder, C. and Verlohren, S. and Morano, I. and Mueller, D.N. and Luft, F.C. and Dietz, R. and Dechend, R. and Karczewski, P.
PLoS ONE 3 (11): e3742. 17 November 2008

2007

Patients who have dilated cardiomyopathy must have a trial of bridge to recovery (pro).
Mueller, J. and Wallukat, G.
Heart Failure Clinics 3 (3): 299-315. July 2007

Autoantibodies against G-Protein-Coupled Receptors Modulate Heart Mast Cells.
Okruhlicova, L. and Morwinski, R. and Schulze, W. and Bartel, S. and Weismann, P. and Tribulova, N. and Wallukat, G.
Cellular and Molecular Immunology 4 (2): 127-133. April 2007

Is parvovirus B19 the cause for autoimmunity against the angiotensin II type receptor?
Stepan, H. and Wallukat, G. and Schultheiss, H.P. and Faber, R. and Walther, T.
Journal of Reproductive Immunology 73 (2): 130-134. April 2007

(-)-Adrenaline elicits positive inotropic, lusitropic, and biochemical effects through beta2 -adrenoceptors in human atrial myocardium from nonfailing and failing hearts, consistent with Gs coupling but not with Gi coupling.
Molenaar, P. and Savarimuthu, S.M. and Sarsero, D. and Chen, L. and Semmler, A.B.T. and Carle, A. and Yang, I. and Bartel, S. and Vetter, D. and Beyerdoerfer, I. and Krause, E.G. and Kaumann, A.J.
Naunyn-Schmiedeberg's Archives of Pharmacology 375 (1): 11-28. March 2007

Agonistic angiotensin II type 1 receptor autoantibodies in postpartum women with a history of preeclampsia.
Hubel, C.A. and Wallukat, G. and Wolf, M. and Herse, F. and Rajakumar, A. and Roberts, J.M. and Markovic, N. and Thadhani, R. and Luft, F.C. and Dechend, R.
Hypertension 49 (3): 612-617. March 2007

Dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia.
Herse, F. and Dechend, R. and Harsem, N.K. and Wallukat, G. and Janke, J. and Qadri, F. and Hering, L. and Mueller, D.N. and Luft, F.C. and Staff, A.C.
Hypertension 49 (3): 604-611. March 2007

2006

Interaction between autoantibodies against the beta(1)-adrenoceptor and isoprenaline in enhancing L-type Ca(2+) current in rat ventricular myocytes.
Christ, T. and Schindelhauer, S. and Wettwer, E. and Wallukat, G. and Ravens, U.
Journal of Molecular and Cellular Cardiology 41 (4): 716-723. October 2006

Relation between circulating AT1 receptor agonistic autoantibodies and soluble fms-like tyrosine kinase 1 in the pathogenesis of preeclampsia.
Stepan, H. and Faber, R. and Wessel, N. and Wallukat, G. and Schultheiss, H.P. and Walther, T.
Journal of Clinical Endocrinology and Metabolism 91 (6): 2424-2427. June 2006

Agonistic antibodies directed at the angiotensin II, AT1 receptor in preeclampsia.
Dechend, R. and Homuth, V. and Wallukat, G. and Mueller, D.N. and Krause, M. and Dudenhausen, J. and Haller, H. and Luft, F.C.
Journal of the Society for Gynecologic Investigation 13 : 79-86. February 2006

2005

Angiotensin II type 1 receptor agonistic antibodies reflect fundamental alterations in the uteroplacental vasculature.
Walther, T. and Wallukat, G. and Jank, A. and Bartel, S. and Schultheiss, H.P. and Faber, R. and Stepan, H.
Hypertension 46 (6): 1275-1279. 31 October 2005

Reduced oxidative stress in parallel to improved cardiac performance one year after selective removal of anti-beta 1-adrenoreceptor autoantibodies in patients with idiopathic dilated cardiomyopathy: data of a preliminary study.
Schimke, I. and Mueller, J. and Dandel, M. and Gremmels, H.D. and Bayer, W. and Wallukat, B. and Wallukat, G. and Hetzer, R.
Journal of Clinical Apheresis 20 (3): 137-142. 12 May 2005

Activating auto-antibodies against the AT1 receptor in preeclampsia.
Dechend, R. and Mueller, D.N. and Wallukat, G. and Homuth, V. and Krause, M. and Dudenhausen, J. and Luft, F.C.
Autoimmunity Reviews 4 (1): 61-65. 1 January 2005

Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia.
Dechend, R. and Gratze, P. and Wallukat, G. and Shagdarsuren, E. and Plehm, R. and Braesen, J.H. and Fiebeler, A. and Schneider, W. and Caluwaerts, S. and Vercruysse, L. and Pijnenborg, R. and Luft, F.C. and Mueller, D.N.
Hypertension 45 (4): 742-746. 1 January 2005

Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection (authors reply inN Engl J Med. 2005 May 12;352(19):2027-8).
Dragun, D. and Mueller, D.N. and Braesen, J.H. and Fritsche, L. and Nieminen-Kelhae, M. and Dechend, R. and Kintscher, U. and Rudolph, B. and Hoebeke, J. and Eckert, D. and Mazak, I. and Plehm, R. and Schoenemann, C. and Unger, T. and Budde, K. and Neumayer, H.H. and Luft, F.C. and Wallukat, G.
New England Journal of Medicine 352 (6): 558-569. 1 January 2005

Effects of immunoglobulin G from patients with dilated cardiomyopathy on rat cardiomyocytes.
Christ, T. and Adolph, E. and Schindelhauer, S. and Wettwer, E. and Dobrev, D. and Wallukat, G. and Ravens, U.
Basic & Clinical Pharmacology & Toxicology 96 (6): 445-452. 1 January 2005

Pathophysiological role of autoantibodies against G-protein-coupled receptors in the cardiovascular system.
Schulze, W. and Kunze, R. and Wallukat, G.
Experimental & Clinical Cardiology 10 (3): 170-172. 1 January 2005

2004

Modulation of the M2 muscarinic acetylcholine receptor activity with monoclonal anti-M2 receptor antibody fragments.
Peter, J.C. and Wallukat, G. and Tugler, J. and Maurice, D. and Roegel, J.C. and Briand, J.P. and Hoebeke, J.
Journal of Biological Chemistry 279 (53): 55697-55706. 31 December 2004

AT1 receptor agonistic antibodies, hypertension, and preeclampsia.
Dechend, R. and Mueller, D.N. and Wallukat, G. and Homuth, V. and Krause, M. and Dudenhausen, J. and Luft, F.C.
Seminars in Nephrology 24 : 571-579. 1 December 2004

Bestimmung agonistischer Autoantikoerper [Identification of agonistic autoantibodies].
Wallukat, G.
DE10327066A1 ; EP1570272 ; WO0451280. 16 September 2004

Peptide gegen Kaelteunvertraeglichkeit hervorrufende Autoantikoerper und ihre Verwendung [Peptides directed against antibodies, which cause cold-intolerance, and the use thereof].
Wallukat, G. and Harrer, T.
DE10311106A1 ; EP1597271 ; WO0467549. 12 August 2004

Effects of ACE gene insertion/deletion polymorphism on response to spironolactone in patients with chronic heart failure.
Cicoira, M. and Rossi, A. and Bonapace, S. and Zanolla, L. and Perrot, A. and Francis, D.P. and Golia, G. and Franceschini, L. and Osterziel, K.J. and Zardini, P.
American Journal of Medicine 116 (10): 657-661. 15 May 2004

OCTAVE und OPERA: Missklaenge der Hypertonietherapie? [OCTAVE and OPERA: discordance in hypertension therapy?].
Philipp, S. and Dietz, R. and Willenbrock, R.
Herz 29 (3): 266-270. 1 May 2004

Non-specific removal of antibodies in patients with idiopathic dilated cardiomyopathy: implications for xenotransplantation.
Knosalla, C. and Mueller, J. and Moran, K. and Wallukat, G. and Hetzer, R. and Cooper, D.K.C.
Journal of Heart and Lung Transplantation 23 (5): 623-626. May 2004

Cellular control of nitric oxide synthase expression and activity in rat cardiomyocytes.
Slezak, J. and Buchwalow, I.B. and Schulze, W. and Karczewski, P. and Wallukat, G. and Samoilova, V.E. and Krause, E.G. and Neumann, J. and Haller, H.
Antioxidants and Redox Signaling 6 (2): 345-352. 1 April 2004

Forced homodimerization by site-directed mutagenesis alters guanylyl cyclase activity of natriuretic peptide receptor B.
Langenickel, T. and Buttgereit, J. and Pagel, I. and Dietz, R. and Willenbrock, R. and Bader, M.
Hypertension 43 (2): 460-465. February 2004

Beneficial effect on cardiac function by intravenous immunoglobulin treatment in patients with dilated cardiomyopathy is not due to neutralization of anti-receptor autoantibody.
Larsson, L. and Mobini, R. and Aukrust, P. and Gullestad, L. and Wallukat, G. and Waagstein, F. and Fu, M.
Autoimmunity 37 (6-7): 489-493. 1 January 2004

Changes in myocardial collagen content before and after left ventricular assist device application in dilated cardiomyopathy.
Liang, H. and Mueller, J. and Weng, Y.G. and Wallukat, G. and Fu, P. and Lin, H.S. and Bartel, S. and Knosalla, C. and Pregla, R. and Hetzer, R.
Chinese Medical Journal 117 (3): 401-407. 1 January 2004

Enhancement of intracellular concentration and biological activity of PNA after conjugation with a cell-penetrating synthetic model peptide.
Oehlke, J. and Wallukat, G. and Wolf, Y. and Ehrlich, A. and Wiesner, B. and Berger, H. and Bienert, M.
European Journal of Biochemistry 271 (14): 3043-3049. 1 January 2004

Immunoadsorption in idiopathic dilated cardiomyopathy, a 3-year follow-up.
Doerffel, W.V. and Wallukat, G. and Doerffel, Y. and Felix, S.B. and Baumann, G.
International Journal of Cardiology 97 (3): 529-534. 1 January 2004

Rat corin gene: molecular cloning and reduced expression in experimental heart failure.
Langenickel, T.H. and Pagel, I. and Buttgereit, J. and Tenner, K. and Lindner, M. and Dietz, R. and Willenbrock, R. and Bader, M.
American Journal of Physiology Heart and Circulatory Physiology 287 (4): H1516-H1521. 1 January 2004

Regulation of caspase 3 and Fas in pressure overload-induced left ventricular dysfunction.
Philipp, S. and Pagel, I. and Hoehnel, K. and Lutz, J. and Buttgereit, J. and Langenickel, T. and Hamet, P. and Dietz, R. and Willenbrock, R.
European Journal of Heart Failure 6 : 845-851. 1 January 2004

Clinical and genetic characteristics of a cardiac actin gene mutations in hypertrophic cardiomyopathy.
Mogensen, J. and Perrot, A. and Andersen, P.S. and Havndrup, O. and Klausen, I.C. and Christiansen, M. and Bross, P. and Egeblad, H. and Bundgaard, H. and Osterziel, K.J. and Haltern, G. and Lapp, H. and Reinecke, P. and Gregersen, N. and Borglum, A.D.
Journal of Medical Genetics 41 : E10. January 2004

2003

Agonistic AT1 receptor autoantibodies and monocyte stimulation in hypertensive patients.
Doerffel, Y. and Wallukat, G. and Bochnig, N. and Homuth, V. and Herberg, M. and Doerffel, W. and Pruss, A. and Chaoui, R. and Scholze, J.
American Journal of Hypertension 16 (10): 827-833. October 2003

scFv single chain antibody variable fragment as inverse agonist of the β(2) -adrenergic receptor.
Peter, J.C. and Eftekhari, P. and Billiald, P. and Wallukat, G. and Hoebeke, J.
Journal of Biological Chemistry 278 (38): 36740-36747. 19 September 2003

Functional and structural characterization of anti-β1-adrenoceptor autoantibodies of spontaneously hypertensive rats.
Wallukat, G. and Podlowski, S. and Nissen, E. and Morwinski, R. and Csonka, C. and Tosaki, A. and Blasig, I.E.
Molecular and Cellular Biochemistry 251 (1-2): 67-75. September 2003

Patients with steroid refractory acute vascular rejection develop agonistic antibodies targeting angiotensin II type 1 receptor.
Dragun, D. and Braesen, J.H. and Schoenemann, C. and Fritsche, L. and Budde, K. and Neumayer, H.H. and Luft, F.C. and Wallukat, G.
Transplantation Proceedings 35 (6): 2104-2105. September 2003

Norepinephrine-induced interleukin-6 increase in rat hearts: differential signal transduction in myocytes and non-myocytes.
Briest, W. and Rassler, B. and Deten, A. and Leicht, M. and Morwinski, R. and Neichel, D. and Wallukat, G. and Ziegelhoeffer, T. and Zimmer, H.G.
Pfluegers Archiv European Journal of Physiology 446 (4): 437-446. July 2003

Hemodynamic improvement and removal of autoantibodies against beta-1-adrenergic receptor by immunoadsorption therapy in dilated cardiomyopathy.
Mobini, R. and Staudt, A. and Felix, S.B. and Baumann, G. and Wallukat, G. and Deinum, J. and Svensson, H. and Hjalmarson, A. and Fu, M.
Journal of Autoimmunity 20 (4): 345-350. June 2003

AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase.
Dechend, R. and Viedt, C. and Mueller, D.N. and Ugele, B. and Brandes, R.P. and Wallukat, G. and Park, J.K. and Janke, J. and Barta, P. and Theuer, J. and Fiebeler, A. and Homuth, V. and Dietz, R. and Haller, H. and Kreuzer, J. and Luft, F.C.
Circulation 107 (12): 1632-1639. 1 April 2003

Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy.
Geier, C. and Perrot, A. and Ozcelik, C. and Binner, P. and Counsell, D. and Hoffmann, K. and Pilz, B. and Martiniak, Y. and Gehmlich, K. and van der Ven, P.F.M. and Furst, D.O. and Vornwald, A. and von Hodenberg, E. and Nuernberg, P. and Scheffold, T. and Dietz, R. and Osterziel, K.J.
Circulation 107 (10): 1390-1395. 18 March 2003

New insights into beta2 adrenoceptor signaling in the adult rat heart.
Bartel, S. and Krause, E.G. and Wallukat, G. and Karczewski, P.
Cardiovascular Research 57 (3): 694-703. 1 March 2003

Agonistic autoantibodies directed against the angiotensin II At1 receptor in patients with preeclampsia.
Wallukat, G. and Neichel, D. and Nissen, E. and Homuth, V. and Luft, F.C.
Canadian Journal of Physiology and Pharmacology 81 (2): 79-83. February 2003

Peptide based adsorbers for therapeutic immunoadsorption.
Roenspeck, W. and Brinckmann, R. and Egner, R. and Gebauer, F. and Winkler, D. and Jekow, P. and Wallukat, G. and Mueller, J. and Kunze, R.
Therapeutic Apheresis 7 (1): 91-97. February 2003

Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance.
Most, P. and Remppis, A. and Pleger, S.T. and Loeffler, E. and Ehlermann, P. and Bernotat, J. and Kleuss, C. and Heierhorst, J. and Ruiz, P. and Witt, H. and Karczewski, P. and Mao, L. and Rockman, H.A. and Duncan, S.J. and Katus, H.A. and Koch, W.J.
Journal of Biological Chemistry 278 (36): 33809-33817. 1 January 2003

2002

Specific removal of β1-adrenergic autoantibodies from patients with idiopathic dilated cardiomyopathy.
Wallukat, G. and Mueller, J. and Hetzer, R.
New England Journal of Medicine 347 (22): 1806. 28 November 2002

Potential role of autoantibodies belonging to the immunoglobulin G-3 subclass in cardiac dysfunction among patients with dilated cardiomyopathy.
Staudt, A. and Boehm, M. and Knebel, F. and Grosse, Y. and Bischoff, C. and Hummel, A. and Dahm, J.B. and Borges, A. and Jochmann, N. and Wernecke, K.D. and Wallukat, G. and Baumann, G. and Felix, S.B.
Circulation 106 (19): 2448-2453. 5 November 2002

The β-adrenergic receptors.
Wallukat, G.
Herz 27 (7): 683-690. November 2002

Spontaneously beating neonatal rat heart myocyte culture - A model to characterize angiotensin II at1 receptor autoantibodies in patients with preeclampsia.
Wallukat, G. and Nissen, E. and Neichel, D. and Harris, J.
In Vitro Cellular & Developmental Biology Animal 38 (7): 376-377. July 2002

Sequenzvarianten des menschlichen beta-1-Adrenozeptorgens und ihre Verwendung [New sequence variants of the human beta-1-adrenoreceptor genes and use thereof].
Wallukat, G. and Podlowski, S. and Wenzel, K. and Mueller, J.
EP1203021. 13 June 2002

Calcineurin in human heart hypertrophy.
Ritter, O. and Hack, S. and Schuh, K. and Roethlein, N. and Perrot, A. and Osterziel, K.J. and Schulte, H.D. and Neyses, L.
Circulation 105 (19): 2265-2269. 14 May 2002

Hypertrophic phenotype of cardiac calcium/ calmodulin-dependent protein kinase II is reversed by angiotensin converting enzyme inhibition.
Hempel, P. and Hoch, B. and Bartel, S. and Karczewski, P.
Basic Research in Cardiology 97 (1): I/96-I/101. May 2002

Peptide des alpha1-adrenergen Rezeptors und ihre Verwendung bei Psoriasis [Peptides of the alpha1-adrenergic receptor and their use for psoriasis].
Wallukat, G.
DE10041560A1 ; WO0216431. 7 March 2002

Expression of human angiotensinogen-renin in rat - effects on transcription and heart function.
Bartel, S. and Hoch, B. and Vetter, D. and Krause, E.G.
Hypertension 39 (2): 219-223. 1 January 2002

Removal of cardiodepressant antibodies in dilated cardiomyopathy by immunoadsorption.
Felix, S.B. and Staudt, A. and Landsberger, M. and Grosse, Y. and Stangl, V. and Spielhagen, T. and Wallukat, G. and Wernecke, K.D. and Baumann, G. and Stangl, K.
Journal of the American College of Cardiology 39 (4): 646-652. 1 January 2002

2001

Peptide des AT1-Rezeptors und ihre Verwendung bei Praeeklampsie und maligner Hypertonie.
Wallukat, G. and Homuth, V. and Luft, F.C.
EP1141018. 15 November 2001

Issues in antiplatelet therapy for UA/NSTEMI.
Chatterjee, K. and Col, J. and Dalby, A.J. and Gulba, D.
European Heart Journal Supplements 3 (Suppl J): J24-J31. August 2001

A monoclonal antibody against the immunodominant epitope of the ribosomal P2β protein of Trypanosoma cruzi interacts with the human β 1-adrenergic receptor.
Mahler, E. and Sepulveda, P. and Jeannequin, O. and Liegeard, P. and Gounon, P. and Wallukat, G. and Eftekhari, P. and Levin, M.J. and Hoebeke, J. and Hontebeyrie, M.
European Journal of Immunology 31 (7): 2210-2216. 4 July 2001

Neue Sequenzvarianten des menschlichen beta1-Adrenozeptorgens und ihre Verwendung.
Wallukat, G. and Podlowski, S. and Wenzel, K. and Mueller, J.
DE19938390A1 ; WO0111039. 8 March 2001

Anti β1-adrenoceptor autoantibodies analyzed in spontaneously beating neonatal rat heart myocyte cultures-comparison of methods.
Wallukat, G. and Nissen, E.
In Vitro Cellular & Developmental Biology Animal 37 (3): 175-176. March 2001

Growth hormone treatment in dilated cardiomyopathy.
Perrot, A. and Ranke, M.B. and Dietz, R. and Osterziel, K.J.
Journal of Cardiac Surgery 16 (2): 127-131. March 2001

A new model of congestive heart failure in the mouse due to chronic volume overload.
Scheuermann-Freestone, M. and Freestone, N.S. and Langenickel, T. and Hoehnel, K. and Dietz, R. and Willenbrock, R.
European Journal of Heart Failure 3 : 535-543. 1 January 2001

Acute hemodynamic effects during immunoadsorption in patients with dilated cardiomyopathy positive for beta 1-adrenoceptor autoantibodies.
Christ, T. and Dobrev, D. and Wallukat, G. and Schueler, S. and Ravens, U.
Methods and Findings in Experimental and Clinical Pharmacology 23 : 141-144. 1 January 2001

Autoantibodies against the beta 1-adrenoceptor from patients with dilated cardiomyopathy prolong action potential duration and enhance contractility in isolated cardiomyocytes.
Christ, T. and Wettwer, E. and Dobrev, D. and Adolph, E. and Knaut, M. and Wallukat, G. and Ravens, U.
Journal of Molecular and Cellular Cardiology 33 (8): 1515-1525. 1 January 2001

Decreased oxidative stress in patients with idiopathic dilated cardiomyopathy one year after immunoglobulin adsorption.
Schimke, I. and Mueller, J. and Priem, F. and Kruse, I. and Schon, B. and Stein, J. and Kunze, R. and Wallukat, G. and Hetzer, R.
Journal of the American College of Cardiology 38 (1): 178-183. 1 January 2001

Expression of alpha1-adrenergic receptor subtypes in heart cell culture.
Luther, H.P. and Podlowski, S. and Schulze, W. and Morwinski, R. and Buchwalow, I. and Baumann, G. and Wallukat, G.
Molecular and Cellular Biochemistry 224 (1-2): 69-79. 1 January 2001

HELLP syndrome in the 18th week of gestation in association with elevated angiotensin AT1-receptor autoantibodies.
Fischer, T. and Wallukat, G. and Schneider, M.P. and Schlembach, D. and Munz, W. and Homuth, V.
European Journal of Obstetrics Gynecology and Reproductive Biology 97 : 255-257. 1 January 2001

Immunohistological changes in dilated cardiomyopathy induced by immunoadsorption therapy and subsequent immunoglobulin substitution.
Staudt, A. and Schaeper, F. and Stangl, V. and Plagemann, A. and Bohm, M. and Merkel, K. and Wallukat, G. and Wernecke, K.D. and Stangl, K. and Baumann, G. and Felix, S.B.
Circulation 103 (22): 2681-2686. 1 January 2001

Inducible nitric oxide synthase in the myocard.
Buchwalow, I.B. and Schulze, W. and Karczewski, P. and Kostic, M.M. and Wallukat, G. and Morwinski, R. and Krause, E.G. and Mueller, J. and Paul, M. and Slezak, J. and Luft, F.C. and Haller, H.
Molecular and Cellular Biochemistry 217 (1-2): 73-82. 1 January 2001

Myocardial adrenergic dysfunction in rats with transgenic, human renin-dependent hypertension.
Bohlender, J. and Hildenbrand, U. and Wagner, K.D. and Guenther, J. and Hempel, P. and Schlegel, W.P. and Luft, F.C. and Krause, E.G. and Bartel, S.
Journal of Hypertension 19 (8): 1453-1463. 1 January 2001

Professor Albert Wollenberger - In memoriam.
Krause, E.G. and Schulze, W. and Wallukat, G.
Journal of Molecular and Cellular Cardiology 33 : 1-2. 1 January 2001

Soluble substances released from postischemic reperfused rat hearts reduce calcium transient and contractility by blocking the L-type calcium channel.
Felix, S.B. and Stangl, V. and Pietsch, P. and Bramlage, P. and Staudt, A. and Bartel, S. and Krause, E.G. and Borschke, J.U. and Wernecke, K.D. and Isenberg, G. and Baumann, G.
Journal of the American College of Cardiology 37 (2): 668-675. 1 January 2001

The GAA repeat expansion in intron 1 of the frataxin gene is related to the severity of cardiac manifestation in patients with Friedreich's ataxia.
Bit-Avragim, N. and Perrot, A. and Schoels, L. and Hardt, C. and Kreuz, F.R. and Zuehlke, C. and Bubel, S. and Laccone, F. and Vogel, H.P. and Dietz, R. and Osterziel, K.J.
Journal of Molecular Medicine 78 : 626-632. 1 January 2001

The upregulation of angiotensin II receptor AT1 in human preeclamptic placenta.
Leung, P.S. and Tsai, S.J. and Wallukat, G. and Leung, T.N. and Lau, T.K.
Molecular and Cellular Endocrinology 184 (1-2): 95-102. 1 January 2001

2000

Induction of cardiomyopathy in severe combined immunodeficiency mice by transfer of lymphocytes from patients with idiopathic dilated cardiomyopathy.
Omerovic, E. and Bollano, E. and Andersson, B. and Kujacic, V. and Schulze, W. and Hjalmarson, A. and Waagstein, F. and Fu, M.
Autoimmunity 32 (4): 271-280. December 2000

Ignition of calcium sparks in arterial and cardiac muscle through caveolae.
Loehn, M. and Fuerstenau, M. and Sagach, V. and Elger, M. and Schulze, W. and Luft, F.C. and Haller, H. and Gollasch, M.
Circulation Research 87 : 1034-1039. 24 November 2000

Midterm follow-up of patients who underwent removal of a left ventricular assist device after cardiac recovery from end-stage dilated cardiomyopathy.
Hetzer, R. and Mueller, J.H. and Weng, Y.G. and Loebe, M. and Wallukat, G.
Journal of Thoracic and Cardiovascular Surgery 120 (5): 843-853. November 2000

Both beta2- and beta1-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of fallot infants, consistent with selective coupling ofbeta2-adrenergic receptors to G(s)-protein.
Molenaar, P. and Bartel, S. and Cochrane, A. and Vetter, D. and Jalali, H. and Pohlner, P. and Burrell, K. and Karczewski, P. and Krause, E.G. and Kaumann, A.
Circulation 102 (15): 1814-1821. 10 October 2000

Modulation of cardiocyte functional activity by antibodies against Trypanosoma cruzi ribosomal P2 protein C terminus.
Sepulveda, P. and Liegeard, P. and Wallukat, G. and Levin, M.J. and Hontebeyrie, M.
Infection and Immunity 68 : 5114-5119. 1 September 2000

Etude comparative de la fonction cardiaque chez le rat transgenique hypertendu, chez le rat spontanement hypertendu et chez le rat normotendu [A comparative study of cardiac function in transgenic hypertensive rats, in spontaneously hypertensive rats and in normotensive rats].
Bohlender, J. and Hildenbrand, U. and Schlegel, W.P. and Hempel, P. and Nissen, E. and Krause, E.G. and Bartel, S.
Archives des Maladies du Coeur et des Vaisseaux 93 (8): 993-996. 1 August 2000

From agonist to antagonist: Fab fragments of an agonist-like monoclonal anti-beta2-adrenoceptor antibody behave as antagonists.
Mijares, A. and Lebesgue, D. and Wallukat, G. and Hoebeke, J.
Molecular Pharmacology 58 (2): 373-379. 1 August 2000

Autoantibodies against the angiotensin receptor AT1 in patients with hypertension.
Fu, M.L.X. and Herlitz, H. and Schulze, W. and Wallukat, G. and Micke, P. and Eftekhari, P. and Sjogren, K.G. and Hjalmarson, A. and Mueller-Esterl, W. and Hoebeke, J.
Journal of Hypertension 18 (7): 945-953. 1 July 2000

Peptide des AT1-Rezeptors und ihre Verwendung, insbesondere fuer die Diagnostider Praeeklampsie.
Wallukat, G. and Homuth, V. and Luft, F.C.
DE19954305A1. 29 June 2000

Immunoadsorption in dilated cardiomyopathy.
Doerffel, W.V. and Wallukat, G. and Baumann, G. and Felix, S.B.
Therapeutic Apheresis 4 (3): 235-238. 1 June 2000

Impairment of cardiac function and bioenergetics in adult transgenic mice overexpressing the bovine growth hormone gene.
Bollano, E. and Omerovic, E. and Bohlooly-Y, M. and Kujacic, V. and Madhu, B. and Tornell, J. and Isaksson, O. and Soussi, B. and Schulze, W. and Fu, M.L.X. and Matejka, G. and Waagstein, F. and Isgaard, J.
Endocrinology 141 (6): 2229-2235. 1 June 2000

AT1 receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor.
Dechend, R. and Homuth, V. and Wallukat, G. and Kreuzer, J. and Park, J.K. and Theuer, J. and Juepner, A. and Gulba, D.C. and Mackman, N. and Haller, H. and Luft, F.C.
Circulation 101 : 2382-2387. 23 May 2000

Autoantibodies against the beta- and muscarinic receptors in cardiomyopathy.
Wallukat, G. and Nissen, E. and Morwinski, R. and Mueller, J.
Herz 25 (3): 261-266. 1 May 2000

Hemodynamic effects of immunoadsorption and subsequent immunoglobulin substitution in dilated cardiomyopathy - Three-month results from a randomized study.
Felix, S.B. and Staudt, A. and Doerffel, W.V. and Stangl, V. and Merkel, K. and Pohl, M. and Doecke, W.D. and Morgera, S. and Neumayer, H.H. and Wernecke, K.D. and Wallukat, G. and Stangl, K. and Baumann, G.
Journal of the American College of Cardiology 35 (6): 1590-1598. 1 May 2000

Myocardial hypertrophy in transgenic mice overexpressing the bovine growth hormone (bGH) gene.
Fu, M.L.X. and Toernell, J. and Schulze, W. and Hoebeke, J. and Isaksson, O.G.P. and Sandstedt, J. and Hjalmarson, A.
Journal of Internal Medicine 247 (5): 546-552. 1 May 2000

A monoclonal antibody directed against an autoimmune epitope on the human beta1-adrenergic receptor recognized in idiopathic dilated cardiomyopathy.
Mobini, R. and Fu, M. and Wallukat, G. and Magnusson, Y. and Hjalmarson, A. and Hoebeke, J.
Hybridoma 19 (2): 135-142. 1 April 2000

Immunadsorption: Eine neue intensivmedizinische Methode zur Rekompensation von Patienten mit dilatativer Kardiomyopathie und Herzinsuffizienz [Immunadsorption - a new therapeutic approach in patients with dilated cardiomyopathy].
Stangl, V. and Staudt, A. and Doerffel, W.V. and Wallukat, G. and Stangl, K. and Baumann, G. and Felix, S.B.
Intensivmedizin und Notfallmedizin 37 (2): 139-145. March 2000

Immunoglobulin adsorption in patients with idiopathic dilated cardiomyopathy.
Mueller, J. and Wallukat, G. and Dandel, M. and Bieda, H. and Brandes, K. and Spiegelsberger, S. and Nissen, E. and Kunze, R. and Hetzer, R.
Circulation 101 (4): 385-391. 1 February 2000

Phosphorylation of phospholamban at threonine-17 in the absence and presence of beta-adrenergic stimulation in neonatal rat cardiomyocytes.
Bartel, S. and Vetter, D. and Schlegel, W.P. and Wallukat, G. and Krause, E.G. and Karczewski, P.
Journal of Molecular and Cellular Cardiology 32 (12): 2173-2185. 1 January 2000

beta1-Adrenoceptor gene variations: a role in idiopathic dilated cardiomyopathy?
Podlowski, S. and Wenzel, K. and Luther, H.P. and Mueller, J. and Bramlage, P. and Baumann, G. and Felix, S.B. and Speer, A. and Hetzer, R. and Koepke, K. and Hoehe, M.R. and Wallukat, G.
Journal of Molecular Medicine 78 (2): 87-93. 1 January 2000

1999

Rational designte Peptide, ihre Herstellung und ihre Verwendung.
Wallukat, G. and Schneider, G. and Schroedl, W. and Mueller, J. and Roenspeck, W. and Wrede, P. and Kunze, R.
DE19826442A1 ; EP1082339. 9 December 1999

Probing the immunological properties of the extracellular domains of the human beta1-adrenoceptor.
Mobini, R. and Magnusson, Y. and Wallukat, G. and Viguier, M. and Hjalmarson, A. and Hoebeke, J.
Journal of Autoimmunity 13 : 179-186. 1 September 1999

Cardiac recovery in dilated cardiomyopathy by unloading with a left ventricular assist device.
Hetzer, R. and Mueller, J. and Weng, Y.G. and Wallukat, G. and Spiegelsberger, S. and Loebe, M.
Annals of Thoracic Surgery 68 : 742-749. 1 August 1999

Quantification of low abundance natriuretic peptide receptor mRNA in rat tissues.
Hoehnel, K. and Dietz, R. and Willenbrock, R.
Clinical Chemistry and Laboratory Medicine 37 : 805-812. 1 August 1999

Agonist-like beta-adrenoceptor antibodies in heart failure.
Wallukat, G. and Mueller, J. and Podlowski, S. and Nissen, E. and Morwinski, R. and Hetzer, R.
American Journal of Cardiology 83 : 75H-79H. 17 June 1999

beta2-adrenergic cAMP signaling is uncoupled from phosphorylation of cytoplasmic proteins in canine heart.
Kuschel, M. and Zhou, Y.Y. and Spurgeon, H.A. and Bartel, S. and Karczewski, P. and Zhang, S.J. and Krause, E.G. and Lakatta, E.G. and Xiao, R.P.
Circulation 99 : 2458-2465. 11 May 1999

Ser 16 prevails over Thr 17 phospholamban phosphorylation in the beta-adrenergic regulation of cardiac relaxation.
Kuschel, M. and Karczewski, P. and Hempel, P. and Schlegel, W.P. and Krause, E.G. and Bartel, S.
American Journal of Physiology Heart and Circulatory Physiology 45 : H1625-H1633. 1 May 1999

Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor.
Wallukat, G. and Homuth, V. and Fischer, T. and Lindschau, C. and Horstkamp, B. and Jupner, A. and Baur, E. and Nissen, E. and Vetter, K. and Neichel, D. and Dudenhausen, J.W. and Haller, H. and Luft, F.C.
Journal of Clinical Investigation 103 (7): 945-952. 1 April 1999

Megalin antagonizes activation of the parathyroid hormone receptor.
Hilpert, J. and Nykjaer, A. and Jacobsen, C. and Wallukat, G. and Nielsen, R. and Moestrup, S.K. and Haller, H. and Luft, F.C. and Christensen, E.I. and Willnow, T.E.
Journal of Biological Chemistry 274 (9): 5620-5625. 26 February 1999

Antagonism by acetyl-RYYRIK-NH2 of G protein activation in rat brain preparations and of chronotropic effect on rat cardiomyocytes evoked by nociceptin/orphanin FQ.
Berger, H. and Albrecht, E. and Wallukat, G. and Bienert, M.
British Journal of Pharmacology 126 : 555-558. 1 February 1999

Autoantibodies against M-2 muscarinic receptors in patients with cardiomyopathy display non-desensitized agonist-like effects.
Wallukat, G. and Fu, H.M. and Matsui, S. and Hjalmarson, A. and Fu, M.L.X.
Life Sciences 64 : 465-469. 8 January 1999

Activation of beta2-adrenergic receptors hastens relaxation and mediates phosphorylation of phospholamban, troponin I, and C-protein in ventricular myocardium from patients with terminal heart failure.
Kaumann, A. and Bartel, S. and Molenaar, P. and Sanders, L. and Burrell, K. and Vetter, D. and Hempel, P. and Karczewski, P. and Krause, E.G.
Circulation 99 : 65-72. 1 January 1999

Dissociation of the effects of forskolin and dibutyryl cAMP on force of contraction and phospholamban phosphorylation in human heart failure.
Neumann, J. and Bartel, S. and Eschenhagen, T. and Haverich, A. and Hirt, S. and Karczewski, P. and Krause, E.G. and Schmitz, W. and Scholz, H. and Stein, B. and Thoenes, M.
Journal of Cardiovascular Pharmacology 33 : 157-162. 1 January 1999

Agonist-like activity of antibodies to angiotensin II receptor subtype 1 (AT1) from rats immunized with AT1 receptor peptide.
Fu, M.L.X. and Leung, P.S. and Wallukat, G. and Bergstroem, G. and Fu, H.M. and Schulze, W. and Herlitz, H.
Blood Pressure 8 (5-6): 317-324. 1999

1998

Agonistic anti-beta1-adrenergic receptor autoantibodies from cardiomyopathy patients reduce the beta1-adrenergic receptor expression in neonatal rat cardiomyocytes.
Podlowski, S. and Luther, H.P. and Morwinski, R. and Mueller, J. and Wallukat, G.
Circulation 98 (22): 2470-2476. 1 December 1998

Peptide design by artificial neural networks and computer-based evolutionary search.
Schneider, G. and Schrodl, W. and Wallukat, G. and Mueller, J. and Nissen, E. and Roenspeck, W. and Wrede, P. and Kunze, R.
Proceedings of the National Academy of Sciences of the United States of America 95 (21): 12179-12184. 13 October 1998

An agonist-like monoclonal antibody against the human beta2- adrenoceptor.
Lebesgue, D. and Wallukat, G. and Mijares, A. and Granier, C. and Argibay, J. and Hoebeke, J.
European Journal of Pharmacology 348 : 123-133. 1 January 1998

Analyse von Kurzzeit-Blutdruck- und Herzfrequenzvariabilitat [Analysis of brief blood pressure and heart rate variability].
Voss, A. and Wessel, N. and Hasart, A. and Haehnel, H. and Prasse, G. and Schirdewan, A. and Osterziel, K.J.
Biomedizinische Technik 43 Suppl. : 106-107. 1 January 1998

Immunochemical and functional characterization of an agonist- like monoclonal antibody against the M2 acetylcholine receptor.
Elies, R. and Fu, L.X.M. and Eftekhari, P. and Wallukat, G. and Schulze, W. and Granier, C. and Hjalmarson, A. and Hoebeke, J.
European Journal of Biochemistry 251 : 659-666. 1 January 1998

Immunohistochemical localization of angiotensin II receptors (AT1) in the heart with anti-peptide antibodies showing a positive chronotropic effect.
Fu, M.L. and Schulze, W. and Wallukat, G. and Elies, R. and Eftekhari, P. and Hjalmarson, K. and Hoebeke, J.
Receptors & Channels 6 : 99-111. 1 January 1998

Phosphorylation of phospholamban correlates with relaxation of coronary artery induced by nitric oxide, adenosine, and prostacyclin in the pig.
Karczewski, P. and Hendrischke, T. and Wolf, W.P. and Morano, I. and Bartel, S. and Schrader, J.
Journal of Cellular Biochemistry 70 : 49-59. 1 January 1998

Site-specific phosphorylation of a phospholamban peptide by cyclic nucleotide- and Ca2+/calmodulin-dependent protein kinases of cardiac sarcoplasmic reticulum.
Karczewski, P. and Kuschel, M. and Baltas, L.G. and Bartel, S. and Krause, E.G.
In: Alterations of Excitation-Contraction Coupling in the Failing Human Heart. Steinkopff, Berlin, 55-65. 1 January 1998

1997

Short-term hemodynamic effects of immunoadsorption in dilated cardiomyopathy.
Doerffel, W.V. and Felix, S.B. and Wallukat, G. and Brehme, S. and Bestvater, K. and Hofmann, T. and Kleber, F.X. and Baumann, G. and Reinke, P.
Circulation 95 (8): 1994-1997. 15 April 1997

Mittel zur Erhoehung der Bindungseigenschaften von Autoantikoerpern gegenueber spezifischen Antigenen, seine Verwendung sowie eine pharmazeutische Zubereitung, die dieses Mittel enthaelt.
Wallukat, G. and Schroedl, W. and Gebauer, F. and Kunze, R.
DE19534195A1. 20 March 1997

Altered expression of PDE1 and PDE4 cyclic nucleotide phosphodiesterase isoforms in 7-oxo-prostacyclin-preconditioned rat heart.
Kostic, M.M. and Erdogan, S. and Rena, G. and Borchert, G. and Hoch, B. and Bartel, S. and Scotland, G. and Huston, E. and Houslay, M. and Krause, E.G.
Journal of Molecular and Cellular Cardiology 29 : 3135-3146. 1 January 1997

Expression of sense and naturally occurring antisense mrna of myosin heavy chain in rat heart tissue and cultivated cardiomyocytes.
Luther, H.P. and Morwinski, R. and Wallukat, G. and Haase, H. and Morano, I.
Journal of Molecular and Cellular Cardiology 29 : 27-35. 1 January 1997

Intracellular localization of inducible nitric oxide synthase in neonatal rat cardiomyocytes in culture.
Buchwalow, I.B. and Schulze, W. and Kostic, M.M. and Wallukat, G. and Morwinski, R.
Acta Histochemica 99 : 231-240. 1 January 1997

Site-specific phosphorylation of a phospholamban peptide by cyclic nucleotide- and Ca2+/calmodulin-dependent protein kinases of cardiac sarcoplasmic reticulum.
Karczewski, P. and Kuschel, M. and Baltas, L.G. and Bartel, S. and Krause, E.G.
Basic Research in Cardiology 92, Suppl.1 : 37-43. 1 January 1997

Temporaere mechanische Linksherzentlastung. Erholung der Herzfunktion bei Patienten mit idiopathischer dilatativer Kardiomyopathie im Endstadium.
Mueller, J. and Wallukat, G. and Weng, Y.G. and Dandel, M. and Spiegelsberger, S. and Semrau, S. and Brandes, K. and Bieda, H. and Hummel, M. and Loebe, M. and Meyer, R. and Hetzer, R.
Herz 22 : 227-236. 1 January 1997

The endogenous cardiac sarcoplasmic reticulum Ca2+/calmodulin dependent kinase is activated in response to beta-adrenergic stimulation and becomes Ca2+independent in intact beating hearts.
Baltas, L.G. and Karczewski, P. and Bartel, S. and Krause, E.G.
FEBS Letters 409 : 131-136. 1 January 1997

Weaning from mechanical cardiac support in patients with idiopathic dilated cardiomyopathy.
Mueller, J. and Wallukat, G. and Weng, Y.G. and Dandel, M. and Spiegelsberger, S. and Semrau, S. and Brandes, K. and Theodoridis, V. and Loebe, M. and Meyer, R. and Hetzer, R.
Circulation 96 : 542-549. 1 January 1997

alpha1-adrenergic receptor antibodies in patients with primary hypertension.
Luther, H.P. and Homuth, V. and Wallukat, G.
Hypertension 29 : 678-682. 1 January 1997

1996

Structural and functional analysis of the B cell epitopes recognized by anti-receptor autoantibodies in patients with chagas' disease.
Elies, R. and Ferrari, I. and Wallukat, G. and Lebesgue, D. and Chiale, P. and Elizari, M. and Rosenbaum, M. and Hoebeke, J. and Levin, M.J.
Journal of Immunology 157 (9): 4203-4211. 1 November 1996

A synthetic peptide corresponding to the second extracellular loop of the human m2 acetylcholine receptor induces pharmacological and morphological changes in cardiomyocytes by active immunization after 6 months in rabbits.
Fu, M.L.X. and Schulze, W. and Wallukat, G. and Hjalmarson, A. and Hoebeke, J.
Clinical Immunology and Immunopathology 78 (2): 203-207. 1 January 1996

Activation of cyclic AMP-dependent protein kinase in cardiomyocytes by anti-beta1-adrenoceptor autoantibodies from patients with idiopathic dilated cardiomyopathy.
Krause, E.G. and Bartel, S. and Beyerdoerfer, I. and Wallukat, G.
Blood Pressure 5 (Suppl.3) : 37-40. 1 January 1996

Agonistic effects of anti-peptide antibodies and autoantibodies directed against adrenergic and cholinergic receptors: absence of desensitization.
Wallukat, G. and Fu, M.L.X. and Magnusson, Y. and Hjalmarson, A. and Hoebeke, J. and Wollenberger, A.
Blood Pressure 5 Suppl.3 : 31-36. 1 January 1996

Early postnatal changes in sarcoplasmic reticulum calcium transport function in spontaneously hypertensive rats.
Freestone, N. and Singh, J. and Krause, E.G. and Vetter, R.
Molecular and Cellular Biochemistry 163/164 : 57-66. 1 January 1996

Functional antagonism by a monoclonal antibody to digoxin in a test system of cultured rat heart myocytes.
Wallukat, G. and Simon, H.U. and Mueller, W.D. and Wolf, I.
Molecular and Cellular Biochemistry 160/161 : 117-120. 1 January 1996

G proteins, adenylyl cyclase and related phosphoproteins in the developing rat heart.
Bartel, S. and Karczewski, P. and Krause, E.G.
Molecular and Cellular Biochemistry 163/164 : 31-38. 1 January 1996

HSP25 in isolated perfused rat hearts: localization and response to hyperthermia.
Hoch, B. and Lutsch, G. and Stahl, J. and Wallukat, G. and Bartel, S. and Krause, E.G. and Benndorf, R. and Karczewski, P.
Molecular and Cellular Biochemistry 160/161 : 231-239. 1 January 1996

Influence of glycosylation inhibitors on dihydropyridine binding to cardiac cells.
Henning, U. and Wallukat, G. and Holtzhauer, M.
Molecular and Cellular Biochemistry 160/161 : 47-52. 1 January 1996

Localization of alpha 1,2,3-subunit isoforms of Na,K-ATPase in cultured neonatal and adult rat myocardium: the immunofluorescence and immunocytochemical study.
Slezak, J. and Schulze, W. and Stefankova, Z. and Okruhlicova, L. and Danihel, L. and Wallukat, G.
Molecular and Cellular Biochemistry 163/164 : 39-45. 1 January 1996

Removal of autoantibodies in dilated cardiomyopathy by immunoadsorption.
Wallukat, G. and Reinke, P. and Doerffel, W.V. and Luther, H.P. and Bestvater, K. and Felix, S.B. and Baumann, G.
International Journal of Cardiology 54 : 191-195. 1 January 1996

beta2-adrenoceptor activation by zinterol causes protein phosphorylation, contractile effects and relaxant effects through a cAMP pathway in human atrium.
Kaumann, A.J. and Sanders, L. and Lynham, J.A. and Bartel, S. and Kuschel, M. and Karczewski, P. and Krause, E.G.
Molecular and Cellular Biochemistry 163/164 : 113-123. 1 January 1996

1995

Molecular mimicry between the immunodominant ribosomal protein PO of Trypanosoma cruzi and a functional epitope on the human beta1-adrenergic receptor.
Ferrari, I. and Levin, M.J. and Wallukat, G. and Elies, R. and Lebesgue, D. and Chiale, P. and Elizari, M. and Rosenbaum, M. and Hoebeke, J.
Journal of Experimental Medicine 182 (1): 59-65. 1 July 1995

Function of C-protein and troponin I phosphorylation in the heart.
Bartel, S. and Karczewski, P. and Morano, I. and Krause, E.G.
Annals of the New York Academy of Sciences 752 : 243-245. 27 March 1995

Anti-beta1-adrenoceptor autoantibodies with chronotropic activity from the serum of patients with dilated cardiomyopathy: mapping ofepitopes in the first and second extracellular loops.
Wallukat, G. and Wollenberger, A. and Morwinski, R. and Pitschner, H.F.
Journal of Molecular and Cellular Cardiology 27 (1): 397-406. 1 January 1995

Cyclic GMP-mediated phospholamban phosphorylation in intact cardiomyocytes.
Bartel, S. and Willenbrock, R. and Haase, H. and Karczewski, P. and Wallukat, G. and Dietz, R. and Krause, E.G.
Biochemical and Biophysical Research Communications 214 (1): 75-80. 1 January 1995

Functional epitope analysis of the second extracellular loop of the human heart muscarinic acetylcholine receptor.
Fu, M.L.X. and Schulze, W. and Wallukat, G. and Hjalmarson, A. and Hoebeke, J.
Journal of Molecular and Cellular Cardiology 27 : 427-436. 1 January 1995

High prevalence of antibodies against beta 1- and beta 2-adrenoceptors in patients with primary electrical cardiac abnormalities.
Chiale, P.A. and Rosenbaum, M.B. and Elizari, M.V. and Hjalmarson, A. and Magnusson, Y. and Wallukat, G. and Hoebeke, J.
Journal of the American College of Cardiology 26 (4): 864-869. 1 January 1995

The beta1 adrenoceptor as antigen: functional aspects.
Wallukat, G. and Kayser, A. and Wollenberger, A.
European Heart Journal 16 Suppl.O : 85-88. 1 January 1995

The sera of spontaneously hypertensive rats contain agonistic auto-antibodies against the beta1-adrenoceptor.
Wallukat, G. and Blasig, I. and Morwinski, R. and Herrmann, H.J. and Rohde, E.
Journal of Hypertension 13 (9): 1031-1036. 1 January 1995

1994

Functional autoimmune epitope on alpha1- adrenergic receptors in patients with malignant hypertension.
Fu, M.L.X. and Herlitz, H. and Wallukat, G. and Hilme, E. and Hedner, T. and Hoebeke, J. and Hjalmarson, A.
Lancet 344 (8938): 1660-1663. 17 December 1994

Modulation of the beta-adrenergic response of cardiomyocytes by specific lipoxygenase products involves their incorporation into phosphatidylinositol and activation of protein kinase C.
Wallukat, G. and Morwinski, R. and Kuehn, H.
Journal of Biological Chemistry 269 (46): 29055-29060. 18 November 1994

Autoimmunity in idiopathic dilated cardiomyopathy. Characterization of antibodies against the beta1- adrenoceptor with positive chronotropic effect.
Magnusson, Y. and Wallukat, G. and Waagstein, F. and Hjalmarson, A. and Hoebeke, J.
Circulation 89 : 2760-2767. 1 January 1994

Characterization of anti-peptide antibodies directed against an extracellular immunogenic epitope on the human alpha1-adrenergic receptor.
Fu, M. and Wallukat, G. and Hjalmarson, A. and Hoebeke, J.
Clinical and Experimental Immunology 97 : 146-151. 1 January 1994

Detection of skeletal muscle calcium channel subunits in cultured neonatal rat cardiac myocytes.
Haase, H. and Wallukat, G. and Flockerzi, V. and Nastainczyk, W. and Hofmann, F.
Receptors & Channels 2 : 41-52. 1 January 1994

Mast cells detected in cultures of neonatal rat heart cells.
Morwinski, R. and Karsten, U. and Wallukat, G.
Agents and Actions 41 : C39-C40. 1 January 1994

1993

Demonstration of membrane-associated phospholiphase A2 in cultivated heart muscle cells by immunogold-technique in surface replicas.
Kriegsmann, J. and Mueller, W.D. and Richter, W. and Wunderlich, J. and Wallukat, G.
Acta Histochemica 95 : 61-66. 1 January 1993

Supersensitivity to beta-adrenoceptor stimulation evoked in cultured neonatal rat heart myocytes by L(+)-lactate and pyruvate.
Wallukat, G. and Wollenberger, A.
Journal of Autonomic Pharmacology 13 : 1-14. 1 January 1993

1992

Autoantikoerper gegen den beta1-adrenergen Rezeptor bei Myokarditis und dilatativer Kardiomyopathie: Lokalisation von zwei Epitopen.
Wallukat, G. and Morwinski, R. and Magnusson, Y. and Hoebeke, J. and Wollenberger, A.
Zeitschrift fuer Kardiologie 81 (Suppl 4): 79-83. 1 January 1992

1991

Modulation of the beta-adrenergic-response in cultured rat heart cells. II. Mammary derived growth inhibitor (MGDI) blocks induction of beta-adrenergic supersensitivity. Dissocition from lipid-binding activity of MDGI.
Wallukat, G. and Boehmer, F.D. and Engstroem, U. and Langen, P. and Hollenberg, M. and Behlke, J. and Kuehn, H. and Grosse, R.
Molecular and Cellular Biochemistry 102 : 49-60. 1 January 1991