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Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
Willnow, D. and Benary, U. and Margineanu, A. and Vignola, M.L. and Konrath, F. and Pongrac, I.M. and Karimaddini, Z. and Vigilante, A. and Wolf, J. and Spagnoli, F.M.
Nature 597 (7874): 87-91. 2 September 2021


A specialized niche in the pancreatic microenvironment promotes endocrine differentiation.
Cozzitorto, C. and Mueller, L. and Ruzittu, S. and Mah, N. and Willnow, D. and Darrigrand, J.F. and Wilson, H. and Khosravinia, D. and Mahmoud, A.A. and Risolino, M. and Selleri, L. and Spagnoli, F.M.
Developmental Cell 55 (2): 150-162. 26 October 2020


Pancreas organogenesis: the interplay between surrounding microenvironment(s) and epithelium-intrinsic factors.
Cozzitorto, C. and Spagnoli, F.M.
Current Topics in Developmental Biology 132 : 221-256. 2019


Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors.
Escot, S. and Willnow, D. and Naumann, H. and Di Francescantonio, S. and Spagnoli, F.M.
Nature Communications 9 (1): 5082. 30 November 2018

The RhoGAP Stard13 controls insulin secretion through F-actin remodeling.
Naumann, H. and Rathjen, T. and Poy, M.N. and Spagnoli, F.M.
Molecular Metabolism 8 : 96-105. February 2018


Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N. and Naumann, H. and Ruzittu, S. and Mah, N. and Pongrac, I.M. and Cozzitorto, C. and Hommel, A. and Andrade-Navarro, M.A. and Bonifacio, E. and Spagnoli, F.M.
Nature Communications 8 : 14127. 13 February 2017


The histone methyltransferase Setd7 promotes pancreatic progenitor identity.
Kofent, J. and Zhang, J. and Spagnoli, F.M.
Development 143 (19): 3573-3581. 1 October 2016

Xenopus as a model system for studying pancreatic development and diabetes.
Kofent, J. and Spagnoli, F.M.
Seminars in Cell & Developmental Biology 51 : 106-116. March 2016


Simply the right time to turn on insulin.
Spagnoli, F.M.
EMBO Journal 34 (13): 1740-1742. 2 July 2015

In vivo reprogramming for tissue repair.
Heinrichs, C. and Spagnoli, F.M. and Berninger, B.
Nature Cell Biology 17 (3): 204-211. 27 February 2015


Recessive mutations in PCBD1 cause a new type of early-onset diabetes.
Simaite, D. and Kofent, J. and Gong, M. and Rüschendorf, F. and Jia, S. and Arn, P. and Bentler, K. and Ellaway, C. and Kühnen, P. and Hoffmann, G.F. and Blau, N. and Spagnoli, F.M. and Hübner, N. and Raile, K.
Diabetes 63 (10): 3557-3564. October 2014

Glimpse into Hox and tale regulation of cell differentiation and reprogramming.
Cerdá-Esteban, N. and Spagnoli, F.M.
Developmental Dynamics 243 (1): 76-87. January 2014


Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence.
Rodríguez-Seguel, E. and Mah, N. and Naumann, H. and Pongrac, I.M. and Cerdá-Esteban, N. and Fontaine, J.F. and Wang, Y. and Chen, W. and Andrade-Navarro, M.A. and Spagnoli, F.M.
Genes & Development 27 (17): 1932-1946. 1 September 2013

Two novel GATA6 mutations cause childhood-onset diabetes mellitus, pancreas malformation and congenital heart disease.
Gong, M. and Simaite, D. and Kühnen, P. and Heldmann, M. and Spagnoli, F. and Blankenstein, O. and Hübner, N. and Hussain, K. and Raile, K.
Hormone Research in Paediatrics 79 (4): 250-256. May 2013

RhoGAP control of pancreas development: putting cells in the right place at the right time.
Zygmunt, T. and Spagnoli, F.M.
Small GTPases 4 (2): 127-131. April 2013

Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas.
Petzold, K.M. and Naumann, H. and Spagnoli, F.M.
Development 140 (1): 126-135. 1 January 2013


A system for ex vivo culturing of embryonic pancreas.
Petzold, K.M. and Spagnoli, F.M.
Journal of Visualized Experiments (66): e3979. 27 August 2012

Where do you come from; where do you go? Pluripotency, differentiation and malfunction of stem cells.
Spagnoli, F.M. and Besser, D. and Benitah, S.A.
EMBO Reports 13 (1): 9-11. January 2012


The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection.
Rosa, A. and Spagnoli, F.M. and Brivanlou, A.H.
Developmental Cell 16 (4): 517-527. 21 April 2009


The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm.
Spagnoli, F.M. and Brivanlou, A.H.
Development 135 (3): 451-461. February 2008


From endoderm to pancreas: a multistep journey.
Spagnoli, F.M.
Cellular and Molecular Life Sciences 64 (18): 2378-2390. September 2007

Balancing BMP signaling through integrated inputs into the Smad1 linker.
Sapkota, G. and Alarcon, C. and Spagnoli, F.M. and Brivanlou, A.H. and Massague, J.
Molecular Cell 25 (3): 441-454. 9 February 2007


Guiding embryonic stem cells towards differentiation: lessons from molecular embryology.
Spagnoli, F.M. and Hemmati-Brivanlou, A.
Current Opinion in Genetics & Development 16 (5): 469-475. October 2006

Snail controls differentiation of hepatocytes by repressing HNF4alpha expression.
Cicchini, C. and Filippini, D. and Coen, S. and Marchetti, A. and Cavallari, C. and Laudadio, I. and Spagnoli, F.M. and Alonzi, T. and Tripodi, M.
Journal of Cellular Physiology 209 (1): 230-238. October 2006

The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification.
Spagnoli, F.M. and Brivanlou, A.H.
Developmental Biology 292 (2): 442-456. 15 April 2006


A full menu for stem-cell research.
Spagnoli, F.M. and Brivanlou, A.H.
Genome Biology 6 (3): 311. 2005


Inhibition of MMH (Met murine hepatocyte) cell differentiation by TGF(beta) is abrogated by pre-treatment with the heritable differentiation effector FGF1.
Spagnoli, F.M. and Cicchini, C. and Tripodi, M. and Weiss, M.C.
Journal of Cell Science 113 (Pt 20): 3639-3647. October 2000


Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver.
Spagnoli, F.M. and Amicone, L. and Tripodi, M. and Weiss, M.C.
Journal of Cell Biology 143 (4): 1101-1112. 16 November 1998


Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes.
Amicone, L. and Spagnoli, F.M. and Spaeth, G. and Giordano, S. and Tommasini, C. and Bernardini, S. and De Luca, V. and Della Rocca, C. and Weiss, M.C. and Comoglio, P.M. and Tripodi, M.
EMBO Journal 16 (3): 495-503. 3 February 1997


Temporal and tissue-specific expression of the MET ORF driven by the complete transcriptional unit of human A1AT gene in transgenic mice.
Amicone, L. and Galimi, M.A. and Spagnoli, F.M. and Tommasini, C. and De Luca, V. and Tripodi, M.
Gene 162 (2): 323-328. 11 September 1995

This list was generated on Fri May 24 02:24:53 2024 CEST.
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