American Journal of Physiology Endocrinology and Metabolism

Intestinal retinol saturase is implicated in the development of obesity and epithelial homeostasis upon injury.
Kiefer, M.F. ORCID: https://orcid.org/0000-0002-6344-2856, Meng, Y., Yang, N., Vahrenbrink, M., Wulff, S., Li, C., Wowro, S.J., Petricek, K.M., Sommerfeld, M., Flores, R.E., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Piepelow, K., Klaus, S., Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512, Guillot, A., Tacke, F., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Schupp, M.
American Journal of Physiology Endocrinology and Metabolism 327 (2): E203-E216. August 2024

Annals of Translational Medicine

Responses of gastric epithelial stem cells and their niche to Helicobacter pylori infection.
Wizenty, J., Tacke, F. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Annals of Translational Medicine 8 (8): 568. April 2020

Biomedicines

The role of Wnt and R-spondin in the stomach during health and disease.
Fischer, A.S. ORCID: https://orcid.org/0000-0002-2176-1779 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Biomedicines 7 (2): 44. 19 June 2019

Cancers

Elevated Flt3L predicts long-term survival in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms.
Detjen, K.M., Otto, R. ORCID: https://orcid.org/0000-0003-3644-743X, Giesecke, Y., Geisler, L., Riemer, P., Jann, H., Grötzinger, C. ORCID: https://orcid.org/0000-0001-9872-3087, Sers, C., Pascher, A., Lüdde, T., Leser, U., Wiedenmann, B., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Roderburg, C. and Hammerich, L. ORCID: https://orcid.org/0000-0003-0557-3927
Cancers 13 (17): 4463. 1 September 2021

Cell Host & Microbe

Quantitative imaging of gut microbiota spatial organization.
Earle, K.A., Billings, G., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Lichtman, J.S., Hansson, G.C., Elias, J.E., Amieva, M.R., Huang, K.C. and Sonnenburg, J.L.
Cell Host & Microbe 18 (4): 478-488. 14 October 2015

Chemodetection and destruction of host urea allows Helicobacter pylori to locate the epithelium.
Huang, J.Y., Sweeney Goers, E., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Zhang, H.C., Remington, S.J., Cantrell, M.A., Kuo, C.J., Guillemin, K. and Amieva, M.R.
Cell Host & Microbe 18 (2): 147-156. 12 August 2015

Cells

S100A4 is a strong negative prognostic marker and potential therapeutic target in adenocarcinoma of the stomach and esophagus.
Treese, C. ORCID: https://orcid.org/0000-0001-9120-6773, Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512, Pötzsch, M., Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, von Winterfeld, M., Berg, E., Hummel, M., Timm, L., Rau, B. ORCID: https://orcid.org/0000-0001-5820-6907, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Daum, S. ORCID: https://orcid.org/0000-0003-0060-6013, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Cells 11 (6): 1056. 21 March 2022

Chirurgisches Forum und DGAV Forum 2010

Darbepoetin-α verringert die Nekroinflammation und mildert die cholestatische Fibrose in Mäusen [Darbepoetin-alpha inhibits the perpetuation of necro-inflammation and attenuates cholestatic fibrosis in mice].
Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Siebert, N., Abshagen, K., Vollmar, B. and Eipel, C.
In: Chirurgisches Forum und DGAV Forum 2010. Deutsche Gesellschaft für Chirurgie, 39 . Springer, Berlin, Heidelberg, 203-205. ISBN 978-3-642-12191-3 2010

Clinical and Translational Gastroenterology

Association of helicobacter pylori positivity with risk of disease and mortality.
Wizenty, J., Koop, P.H., Clusmann, J., Tacke, F., Trautwein, C., Schneider, K.M., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Schneider, C.V.
Clinical and Translational Gastroenterology 14 (9): e00610. September 2023

Current Topics in Microbiology and Immunology

Gastric stem cell biology and helicobacter pylori infection.
Wizenty, J. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Current Topics in Microbiology and Immunology 444 : 1-24. 18 January 2024

Digestive Diseases

Coevolution between the human microbiota and the epithelial immune system.
Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Meyer, T.F.
Digestive Diseases 34 (3): 190-193. March 2016

EMBO Journal

Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3-Lgr4 axis.
Wizenty, J. ORCID: https://orcid.org/0000-0003-4261-0416, Müllerke, S., Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Fischer, A.S. ORCID: https://orcid.org/0000-0002-2176-1779, Mollenkopf, H.J., Berger, H., Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
EMBO Journal 41 (13): e109996. 4 July 2022

EMBO Molecular Medicine

Epithelial response to IFN-γ promotes SARS-CoV-2 infection.
Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Trimpert, J., Vladimirova, D., Goosmann, C., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Schmuck, R., Mollenkopf, H.J., Brinkmann, V., Tacke, F., Osterrieder, N. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
EMBO Molecular Medicine 13 (4): e13191. 9 April 2021

Frontiers in Endocrinology

Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting.
Bolduan, F., Wetzel, A., Giesecke, Y., Eichhorn, I., Alenina, N. ORCID: https://orcid.org/0000-0002-6071-5433, Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921, Wiedenmann, B. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Frontiers in Endocrinology 15 : 1331231. 17 April 2024

Frontiers in Oncology

Unwelcome guests – the role of gland-associated Helicobacter pylori infection in gastric carcinogenesis.
Beccaceci, G. ORCID: https://orcid.org/0000-0002-6453-3725 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Frontiers in Oncology 13 : 1171003. 21 April 2023

Gastroenterology

Stem cells, helicobacter pylori and mutational landscape: utility of preclinical models to understand carcinogenesis and to direct management of gastric cancer.
Liabeuf, D., Oshima, M., Stange, D.E. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Gastroenterology 162 (4): 1067-1087. April 2022

Helicobacter pylori depletes cholesterol in gastric glands to prevent interferon gamma signaling and escape the inflammatory response.
Morey, P., Pfannkuch, L., Pang, E., Boccellato, F., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Imai-Matsushima, A., Dyer, V., Koch, M., Mollenkopf, H.J., Schlaermann, P. and Meyer, T.F.
Gastroenterology 154 (5): 1391-1404. April 2018

Helicobacter pylori activates and expands Lgr5(+) stem cells through direct colonization of the gastric glands.
Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Rothenberg, M.E., Logan, C.Y., Lee, J.Y., Honaker, R.W., Cooper, R.L., Passarelli, B., Camorlinga, M., Bouley, D.M., Alvarez, G., Nusse, R., Torres, J. and Amieva, M.R.
Gastroenterology 148 (7): 1392-1404. June 2015

Gut Microbes

Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis.
Harnack, C., Berger, H., Liu, L., Mollenkopf, H.J., Strowig, T. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Gut Microbes 15 (1): 2233689. 10 July 2023

Hepatobiliary Surgery and Nutrition

Mucosa-associated microbiota alterations in primary sclerosing cholangitis (PSC) before and after liver transplantation—who is calling the shots?
Demir, M. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Hepatobiliary Surgery and Nutrition 12 (5): 795-797. 1 October 2023

Hepatology Communications

Long-term impact of scheduled regular endoscopic interventions for patients with primary sclerosing cholangitis.
Özdirik, B. ORCID: https://orcid.org/0000-0002-8885-737X, Veltzke-Schlieker, W., Nicklaus, J.M., Berger, H., Schmidt, D., Leonhardt, S., Penndorf, V., Adler, A., Müller, T., Wree, A., Tacke, F. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Hepatology Communications 8 (9): e0494. September 2024

Biliary microbial patterns in primary sclerosing cholangitis are linked to poorer transplant-free survival.
Özdirik, B. ORCID: https://orcid.org/0000-0002-8885-737X, Scherf, M., Brumercek, A., Nicklaus, J.M., Kruis, T., Haber, P.K., Pratschke, J., Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Hepatology Communications 7 (6): e0156. June 2023

Hepatology International

Hepatobiliary long-term consequences of COVID-19: dramatically increased rate of secondary sclerosing cholangitis in critically ill COVID-19 patients.
Leonhardt, S., Jürgensen, C., Frohme, J., Grajecki, D., Adler, A., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Leonhardt, J., Voll, J.M., Kruse, J.M., Körner, R., Eckardt, K.U., Janssen, H.J., Gebhardt, V., Schmittner, M.D., Frey, C., Müller-Ide, H., Bauer, M., Thibeault, C., Kurth, F., Sander, L.E., Müller, T. and Tacke, F.
Hepatology International 17 (6): 1610-1625. December 2023

Hygiene und Medizin

Wie das Immunsystem SARS-CoV-2 den Weg ebnet [How the immune system paves the way for SARS-CoV-2].
Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Hygiene und Medizin 46 (3): 22-23. 2021

International Journal of Clinical and Experimental Pathology

Hepatoprotection in bile duct ligated mice mediated by darbepoetin-α is not caused by changes in hepatobiliary transporter expression.
Eipel, C., Menschikow, E., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Kuhla, A., Abshagen, K. and Vollmar, B.
International Journal of Clinical and Experimental Pathology 6 (1): 80-90. 1 January 2013

International Journal of Health Planning and Management

Health workforce response to Covid-19: What pandemic preparedness planning and action at the federal and state levels in Germany? Germany's health workforce responses to Covid-19.
Köppen, J. ORCID: https://orcid.org/0000-0001-7941-641X, Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512 and Maier, C.B. ORCID: https://orcid.org/0000-0002-7734-2258
International Journal of Health Planning and Management 36 (S1): 71-91. May 2021

International Journal of Medical Microbiology

Defence and adaptation mechanisms of the intestinal epithelium upon infection.
Iftekhar, A. ORCID: https://orcid.org/0000-0002-0001-5590 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
International Journal of Medical Microbiology 311 (3): 151486. April 2021

International Journal of Molecular Sciences

The role of microbiota in primary sclerosing cholangitis and related biliary malignancies.
Özdirik, B. ORCID: https://orcid.org/0000-0002-8885-737X, Müller, T. ORCID: https://orcid.org/0000-0003-3426-5421, Wree, A., Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
International Journal of Molecular Sciences 22 (13): 6975. 1 July 2021

Microbe-driven genotoxicity in gastrointestinal carcinogenesis.
Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
International Journal of Molecular Sciences 21 (20): 7439. 2 October 2020

Internist

Helicobacter pylori - neue Aspekte kommender Leitlinien [Helicobacter pylori - new aspects of forthcoming guidelines].
Schulz, C., Fischbach, W., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Schütte, K., Suerbaum, S. and Malfertheiner, P.
Internist 63 (4): 367-371. 1 March 2022

JGH Open

Persistent abdominal pain and diarrhea after appendectomy-Crohn's disease versus intestinal tuberculosis.
Wizenty, J., Maibier, M. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
JGH Open 9 (4): e70157. April 2025

Journal of Cancer Research and Clinical Oncology

Osteopontin is a prognostic circulating biomarker in patients with neuroendocrine neoplasms.
Kidess, E., Giesecke, Y., Eichhorn, I., Mohr, R., Jann, H., Fischer, C., Wiedenmann, B., Roderburg, C., Tacke, F. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Journal of Cancer Research and Clinical Oncology 149 (12): 10925-10933. September 2023

Journal of Clinical Investigation

R-spondin-YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice.
Fischer, A.S. ORCID: https://orcid.org/0000-0002-2176-1779, Müllerke, S., Arnold, A., Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Berger, H., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Mollenkopf, H.J. ORCID: https://orcid.org/0000-0003-1167-4783, Wizenty, J. ORCID: https://orcid.org/0000-0003-4261-0416, Horst, D. ORCID: https://orcid.org/0000-0003-4755-5743, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Journal of Clinical Investigation 132 (21): e151363. 1 November 2022

Journal of Clinical Medicine

Soluble urokinase plasminogen activator receptor levels are associated with severity of fibrosis in patients with primary sclerosing cholangitis.
Özdirik, B. ORCID: https://orcid.org/0000-0002-8885-737X, Maibier, M., Scherf, M., Nicklaus, J.M., Frohme, J., Puengel, T. ORCID: https://orcid.org/0000-0003-2662-6127, Meyer Zum Büschenfelde, D., Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Mueller, T. ORCID: https://orcid.org/0000-0003-3426-5421 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Journal of Clinical Medicine 11 (9): 2479. 28 April 2022

Laboratory Investigation

Darbepoetin-α inhibits the perpetuation of necro-inflammation and delays the progression of cholestatic fibrosis in mice.
Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Siebert, N., Zechner, D. ORCID: https://orcid.org/0000-0002-2075-7540, Menschikow, E., Abshagen, K., Vollmar, B. and Eipel, C.
Laboratory Investigation 90 (10): 1447-1456. October 2010

Life Science Alliance

Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells.
Grinat, J. ORCID: https://orcid.org/0000-0003-0152-4941, Kosel, F., Goveas, N. ORCID: https://orcid.org/0000-0002-2531-5514, Kranz, A. ORCID: https://orcid.org/0000-0002-7481-0220, Alexopoulou, D. ORCID: https://orcid.org/0000-0002-3715-1756, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Stewart, A.F. and Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X
Life Science Alliance 5 (4): e202101187. April 2022

Liver International

Faecal cytolysin is associated with worse survival in patients with primary sclerosing cholangitis.
Özdirik, B., Berger, H., Tonetti, F.R., Cabré, N., Treichel, N., Clavel, T., Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Schnabl, B. ORCID: https://orcid.org/0000-0002-6281-825X
Liver International 45 (4): e16181. April 2025

Nature

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.
Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Logan, C.Y., Kapalczynska, M., Mollenkopf, H.J., Berger, H., Wiedenmann, B., Nusse, R., Amieva, M.R. and Meyer, T.F.
Nature 548 (7668): 451-455. 24 August 2017

Nature Cell Biology

R-spondin-3 induces secretory, antimicrobial Lgr5(+) cells in the stomach.
Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Del Mar Reinés, M., Müllerke, S., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Kapalczynska, M., Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, Bakker, E.R.M., Mollenkopf, H.J. ORCID: https://orcid.org/0000-0003-1167-4783, Rothenberg, M.E., Wiedenmann, B., Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693 and Meyer, T.F. ORCID: https://orcid.org/0000-0002-6120-8679
Nature Cell Biology 21 (7): 812-823. July 2019

Nature Communications

Extrusion of BMP2+ surface colonocytes promotes stromal remodeling and tissue regeneration.
Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Liu, L., Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, van den Heuvel, J., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Müllerke, S., Bayram, S. ORCID: https://orcid.org/0009-0009-5245-5473, Beccaceci, G. ORCID: https://orcid.org/0000-0002-6453-3725, de Jonge, H. ORCID: https://orcid.org/0000-0003-2777-4084, Gherardi, E. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Communications 16 (1): 4131. 3 May 2025

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.
Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512, Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Beccaceci, G. ORCID: https://orcid.org/0000-0002-6453-3725, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, Li, H. ORCID: https://orcid.org/0000-0001-5677-3377, Liu, L. ORCID: https://orcid.org/0000-0002-9553-5475, Müllerke, S., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Heymann, F., Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Communications 14 (1): 3025. 25 May 2023

BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.
Kapalczynska, M., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Maertzdorf, J., Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Muellerke, S., Zuo, X. ORCID: https://orcid.org/0000-0002-8593-1132, Vidal, R. ORCID: https://orcid.org/0000-0003-4217-2014, Shureiqi, I. ORCID: https://orcid.org/0000-0003-2019-938X, Fischer, A.S. ORCID: https://orcid.org/0000-0002-2176-1779, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, Kidess, E., Mollenkopf, H.J. ORCID: https://orcid.org/0000-0003-1167-4783, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Meyer, T.F. ORCID: https://orcid.org/0000-0002-6120-8679 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Communications 13 (1): 1577. 24 March 2022

Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.
Iftekhar, A. ORCID: https://orcid.org/0000-0002-0001-5590, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, Bouznad, N., Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Boccellato, F. ORCID: https://orcid.org/0000-0001-6013-7154, Dobrindt, U., Hermeking, H., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Meyer, T.F. ORCID: https://orcid.org/0000-0002-6120-8679
Nature Communications 12 (1): 1003. 12 February 2021

R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.
Harnack, C. ORCID: https://orcid.org/0000-0003-0067-4921, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, Antanaviciute, A. ORCID: https://orcid.org/0000-0002-9019-2215, Vidal, R. ORCID: https://orcid.org/0000-0003-4217-2014, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Simmons, A., Meyer, T.F. ORCID: https://orcid.org/0000-0002-6120-8679 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Communications 10 (1): 4368. 25 September 2019

Nature Reviews Gastroenterology & Hepatology

Defining the mucosal ecosystem: epithelial–mesenchymal interdependence in gastrointestinal health and disease.
England, Frances J., Lin, Manqiang ORCID: https://orcid.org/0000-0003-4093-9277, Sigal, Michael ORCID: https://orcid.org/0000-0003-4772-0761 and Leedham, Simon J.
Nature Reviews Gastroenterology & Hepatology 22 (11): 741-754. November 2025

Helicobacter pylori, microbiota and gastric cancer - principles of microorganism-driven carcinogenesis.
Wizenty, J. ORCID: https://orcid.org/0000-0003-4261-0416 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Reviews Gastroenterology & Hepatology 22 (5): 296-313. May 2025

Proceedings of the National Academy of Sciences of the United States of America

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Grinat, J. ORCID: https://orcid.org/0000-0003-0152-4941, Kosel, F., Liu, L., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Vidal, R.O. ORCID: https://orcid.org/0000-0003-4217-2014, Keil, M. ORCID: https://orcid.org/0000-0002-6009-9845, Haybaeck, J. ORCID: https://orcid.org/0000-0001-5518-3359, Robine, S. ORCID: https://orcid.org/0000-0002-8885-0389, Louvard, D. ORCID: https://orcid.org/0000-0001-5956-7755, Regenbrecht, C. ORCID: https://orcid.org/0000-0001-9494-5977, Sporbert, A. ORCID: https://orcid.org/0000-0002-3738-1295, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, von Eyss, B. ORCID: https://orcid.org/0000-0002-4731-6841, Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 118 (22): e2019699118. 1 June 2021

Science Advances

p53 terminates the regenerative fetal-like state after colitis-associated injury.
Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512, Bayram, Ş. ORCID: https://orcid.org/0009-0009-5245-5473, Wetzel, A., Harnack, C., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Fischer, A.S. ORCID: https://orcid.org/0000-0002-2176-1779, Liu, L. ORCID: https://orcid.org/0000-0002-9553-5475, Beccacec, G. ORCID: https://orcid.org/0000-0002-6453-3725, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Monteiro, B.J.E. ORCID: https://orcid.org/0000-0001-9718-2776, Macino, M. ORCID: https://orcid.org/0000-0002-8730-9005, Flores, R.E. ORCID: https://orcid.org/0000-0001-6500-8407, Engelmann, C., Mollenkopf, H.J. ORCID: https://orcid.org/0000-0003-1167-4783, Schupp, M. ORCID: https://orcid.org/0000-0003-3720-1052, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Science Advances 10 (43): eadp8783. 25 October 2024

Scientific Reports

Small intestinal neuroendocrine tumors lack early genomic drivers, acquire DNA repair defects and harbor hallmarks of low REST expression.
Bolduan, F., Müller-Bötticher, N., Debnath, O. ORCID: https://orcid.org/0009-0009-2845-055X, Eichhorn, I., Giesecke, Y., Wetzel, A., Sahay, S., Zemojtel, T., Jaeger, M., Ungethuem, U., Roderburg, C., Kunze, C.A., Lehmann, A., Horst, D., Tacke, F., Eils, R., Wiedenmann, B., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X
Scientific Reports 15 (1): 17969. 23 May 2025

Seminars in Liver Disease

Role of intestinal barrier disruption to acute-on-chronic liver failure.
Pohl, J., Aretakis, D., Tacke, F., Engelmann, C. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Seminars in Liver Disease 45 (1): 52-65. March 2025

Signal Transduction and Targeted Therapy

Human embryo models: unveiling sophisticated self-organization of stem cells during post-implantation stages.
Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Signal Transduction and Targeted Therapy 8 (1): 419. 6 November 2023

The Gut Microbiome in Health and Disease

Microbiome and diseases: colorectal cancer.
Iftekhar, A., Sperlich, A., Janssen, K.P. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
In: The Gut Microbiome in Health and Disease. Springer, Cham, 231-249. ISBN 978-3-319-90544-0 2018

Therapeutische Umschau

Neuroendokrine Neoplasien des gastroenteropankreatischen Systems [Gastroenteropancreatic neuro-endocrine neoplasms].
Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Pape, F. and Wiedenmann, B.
Therapeutische Umschau 69 (10): 591-596. October 2012

Translational Gastroenterology and Hepatology

A fucoidan plant drink reduces Helicobacter pylori load in the stomach: a real-world study.
Teng, Q.L., Sui, S.J., Zhu, Z., Gao, Q., Ge, H., Wang, K.Q., Lino-Silva, L.S., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, White, J.R., Peng, Q.H. and Wei, Y.Z.
Translational Gastroenterology and Hepatology 8 : 34-34. 30 October 2023

Zeitschrift fur Gastroenterologie

Synchrones Auftreten eines Adenokarzinoms und eines Non-Hodgkin B-Zell-Lymphoms bei einem Patienten mit einem variablen Immundefektsyndrom (CVID) [When malignancy hits twice - synchronous gastric carcinoma and non-Hodgkin-B-cell lymphoma in a patient with common variable immunodeficiency].
Krick, D., Hauptmann, K., Penndorf, V., Tacke, F., Krüger, R., von Bernuth, H. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Zeitschrift fur Gastroenterologie 61 (7): 827-831. July 2023