Article
Synthetic lethality by PARP inhibitors: new mechanism uncovered based on unresolved transcription-replication conflicts.
Kolesnichenko, M. and Scheidereit, C.
Signal Transduction and Targeted Therapy 9
(1): 179.
29 July 2024
Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner, N., Cauchy, P., Franke, V., Giefing, M., Fornes, O., Vankadari, N., Assi, S.A., Costanza, M., Weniger, M.A., Akalin, A., Anagnostopoulos, I., Bukur, T., Casarotto, M.G., Damm, F., Daumke, O., Edginton-White, B., Gebhardt, J.C.M., Grau, M., Grunwald, S., Hansmann, M.L., Hartmann, S., Huber, L., Kärgel, E., Lusatis, S., Noerenberg, D., Obier, N., Pannicke, U., Fischer, A., Reisser, A., Rosenwald, A., Schwarz, K., Sundararaj, S., Weilemann, A., Winkler, W., Xu, W., Lenz, G., Rajewsky, K., Wasserman, W.W., Cockerill, P.N., Scheidereit, C., Siebert, R., Küppers, R., Grosschedl, R., Janz, M., Bonifer, C. and Mathas, S.
Nature Communications 14
(1): 6947.
7 November 2023
A computational model of the DNA damage-induced IKK/ NF-κB pathway reveals a critical dependence on irradiation dose and PARP-1.
Konrath, F., Willenbrock, M., Busse, D., Scheidereit, C. and Wolf, J.
iScience 26
(10): 107917.
20 October 2023
CLK2 and CLK4 are regulators of DNA damage-induced NF-κB targeted by novel small molecule inhibitors.
Mucka, P., Lindemann, P., Bosco, B., Willenbrock, M., Radetzki, S., Neuenschwander, M., Brischetto, C., von Kries, J.P., Nazaré, M. and Scheidereit, C.
Cell Chemical Biology 30
(10): 1303-1312.e3.
19 October 2023
TSG101 associates with PARP1 and is essential for PARylation and DNA damage-induced NF-κB activation.
Tufan, A.B., Lazarow, K., Kolesnichenko, M., Sporbert, A., von Kries, J.P. and Scheidereit, C.
EMBO Journal 41
(21): e110372.
2 November 2022
Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K., Kny, M., Huang, N., Klassert, T.E., Stock, M., Hahn, A., Graeger, S., Todiras, M., Schmidt, S., Chamling, B., Willenbrock, M., Groß, S., Biedenweg, D., Heuser, A., Scheidereit, C., Butter, C., Felix, S.B., Otto, O., Luft, F.C., Slevogt, H. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 12
(6): 1653-1668.
December 2021
NF-κB determines Paneth versus goblet cell fate decision in the small intestine.
Brischetto, C., Krieger, K., Klotz, C., Krahn, I., Kunz, S., Kolesnichenko, M., Mucka, P., Heuberger, J., Scheidereit, C. and Schmidt-Ullrich, R.
Development 148
(21): dev199683.
November 2021
Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence.
Kolesnichenko, M., Mikuda, N., Höpken, U.E., Kärgel, E., Uyar, B., Tufan, A.B., Milanovic, M., Sun, W., Krahn, I., Schleich, K., von Hoff, L., Hinz, M., Willenbrock, M., Jungmann, S., Akalin, A., Lee, S., Schmidt-Ullrich, R., Schmitt, C.A. and Scheidereit, C.
EMBO Journal 40
(6): e104296.
15 March 2021
Overactivation of the NF-κB pathway impairs molar enamel formation.
Yamada, A., Kawasaki, M., Miake, Y., Yamada, Y., Blackburn, J., Kawasaki, K., Trakanant, S., Nagai, T., Nihara, J., Kudo, T., Meguro, F., Schmidt-Ullrich, R., Liu, B., Hu, Y., Page, A., Ramírez, Á., Sharpe, P.T., Maeda, T., Takagi, R. and Ohazama, A.
Oral Diseases 26
(7): 1513-1522.
October 2020
NF-κB signaling in tanycytes mediates inflammation-induced anorexia.
Böttcher, M., Müller-Fielitz, H., Sundaram, S.M., Gallet, S., Neve, V., Shionoya, K., Zager, A., Quan, N., Liu, X., Schmidt-Ullrich, R., Haenold, R., Wenzel, J., Blomqvist, A., Engblom, D., Prevot, V. and Schwaninger, M.
Molecular Metabolism 39
: 101022.
September 2020
A quantitative modular modeling approach reveals the effects of different A20 feedback implementations for the NF-κB signaling dynamics.
Mothes, J., Ipenberg, I., Arslan, S.Ç., Benary, U., Scheidereit, C. and Wolf, J.
Frontiers in Physiology 11
: 896.
28 July 2020
Deficiency in IκBα in the intestinal epithelium leads to spontaneous inflammation and mediates apoptosis in the gut.
Mikuda, N., Schmidt-Ullrich, R., Kärgel, E., Golusda, L., Wolf, J., Höpken, U.E., Scheidereit, C., Kühl, A.A. and Kolesnichenko, M.
Journal of Pathology 251
(2): 160-174.
June 2020
Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Dembny, P., Newman, A.G., Singh, M., Hinz, M., Szczepek, M., Krüger, C., Adalbert, R., Dzaye, O., Trimbuch, T., Wallach, T., Kleinau, G., Derkow, K., Richard, B.C., Schipke, C., Scheidereit, C., Stachelscheid, H., Golenbock, D., Peters, O., Coleman, M., Heppner, F.L., Scheerer, P., Tarabykin, V., Ruprecht, K., Izsvák, Z., Mayer, J. and Lehnardt, S.
JCI Insight 5
(7): e131093.
9 April 2020
Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Hahn, A., Kny, M., Pablo-Tortola, C., Todiras, M., Willenbrock, M., Schmidt, S., Schmoeckel, K., Jorde, I., Nowak, M., Jarosch, E., Sommer, T., Bröker, B.M., Felix, S.B., Scheidereit, C., Weber-Carstens, S., Butter, C., Luft, F.C. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 11
(1): 103-119.
February 2020
In contrast to Western diet, a plant-based, high-fat, low-sugar diet does not exacerbate retinal endothelial injury in streptozotocin-induced diabetes.
Barakat, A., Nakao, S., Zandi, S., Sun, D., Schmidt-Ullrich, R., Hayes, K.C. and Hafezi-Moghadam, A.
FASEB Journal 33
(9): 10327-10338.
September 2019
Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V., McShane, E., Schulz-Beiss, K.W., Patone, G., Schleussner, N., Kolesnichenko, M., Hübner, N., Daumke, O., Selbach, M., Akalin, A., Mathas, S. and Scheidereit, C.
Blood 133
(13): 1489-1494.
28 March 2019
Canonical BMP signaling in tubular cells mediates recovery after acute kidney injury.
Vigolo, E., Markó, L., Hinze, C., Müller, D.N., Schmidt-Ullrich, R. and Schmidt-Ott, K.M.
Kidney International 95
(1): 108-122.
January 2019
The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N., Kolesnichenko, M., Beaudette, P., Popp, O., Uyar, B., Sun, W., Tufan, A.B., Perder, B., Akalin, A., Chen, W., Mertins, P., Dittmar, G., Hinz, M. and Scheidereit, C.
EMBO Journal 37
(24): e98658.
14 December 2018
The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.
Schleussner, N., Merkel, O., Costanza, M., Liang, H.C., Hummel, F., Romagnani, C., Durek, P., Anagnostopoulos, I., Hummel, M., Jöhrens, K., Niedobitek, A., Griffin, P.R., Piva, R., Sczakiel, H.L., Woessmann, W., Damm-Welk, C., Hinze, C., Stoiber, D., Gillissen, B., Turner, S.D., Kaergel, E., von Hoff, L., Grau, M., Lenz, G., Dörken, B., Scheidereit, C., Kenner, L., Janz, M. and Mathas, S.
Leukemia 32
(9): 1994-2007.
September 2018
NF-κB participates in mouse hair cycle control and plays distinct roles in the various pelage hair follicle types.
Krieger, K., Millar, S.E., Mikuda, N., Krahn, I., Kloepper, J.E., Bertolini, M., Scheidereit, C., Paus, R. and Schmidt-Ullrich, R.
Journal of Investigative Dermatology 138
(2): 256-264.
February 2018
Endothelial NF-κB blockade abrogates ANCA-induced GN.
Choi, M., Schreiber, A., Eulenberg-Gustavus, C., Scheidereit, C., Kamps, J. and Kettritz, R.
Journal of the American Society of Nephrology 28
(11): 3191-3204.
November 2017
NF-κB activation protects oligodendrocytes against inflammation.
Stone, S., Jamison, S., Yue, Y., Durose, W., Schmidt-Ullrich, R. and Lin, W.
Journal of Neuroscience 37
(38): 9332-9344.
20 September 2017
Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells.
Riemann, M., Andreas, N., Fedoseeva, M., Meier, E., Weih, D., Freytag, H., Schmidt-Ullrich, R., Klein, U., Wang, Z.Q. and Weih, F.
Journal of Autoimmunity 81
: 56-67.
July 2017
Regional regulation of filiform tongue papillae development by Ikkα/Irf6.
Kawasaki, M., Kawasaki, K., Oommen, S., Blackburn, J., Watanabe, M., Nagai, T., Kitamura, A., Maeda, T., Liu, B., Schmidt-Ullrich, R., Akiyama, T., Inoue, J.I., Hammond, N.L., Sharpe, P.T. and Ohazama, A.
Developmental Dynamics 245
(9): 937-946.
September 2016
Tubular epithelial NF-κB activity regulates ischemic AKI.
Markó, L., Vigolo, E., Hinze, C., Park, J.K., Roël, G., Balogh, A., Choi, M., Wübken, A., Cording, J., Blasig, I.E., Luft, F.C., Scheidereit, C., Schmidt-Ott, K.M., Schmidt-Ullrich, R. and Müller, D.N.
Journal of the American Society of Nephrology 27
(9): 2658-2669.
September 2016
LHX2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.
Tomann, P., Paus, R., Millar, S.E., Scheidereit, C. and Schmidt-Ullrich, R.
Development 143
(9): 1512-1522.
1 May 2016
A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P., Kaergel, E., Heinig, M., Fontaine, J.F., Patone, G., Muro, E.M., Mathas, S., Hummel, M., Andrade-Navarro, M.A., Hübner, N. and Scheidereit, C.
Genome Medicine 8
(1): 28.
17 March 2016
Ectodysplasin/NF-κB promotes mammary cell fate via Wnt/β-catenin pathway.
Voutilainen, M., Lindfors, P.H., Trela, E., Loennblad, D., Shirokova, V., Elo, T., Rysti, E., Schmidt-Ullrich, R., Schneider, P. and Mikkola, M.L.
PLoS Genetics 11
(11): e1005676.
18 November 2015
Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Oden, F., Marino, S.F., Brand, J., Scheu, S., Kriegel, C., Olal, D., Takvorian, A., Westermann, J., Yilmaz, B., Hinz, M., Daumke, O., Höpken, U.E., Müller, G. and Lipp, M.
Molecular Oncology 9
(7): 1348-1358.
August 2015
RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.
Murakawa, Y., Hinz, M., Mothes, J., Schuetz, A., Uhl, M., Wyler, E., Yasuda, T., Mastrobuoni, G., Friedel, C.C., Dölken, L., Kempa, S., Schmidt-Supprian, M., Blüthgen, N., Backofen, R., Heinemann, U., Wolf, J., Scheidereit, C. and Landthaler, M.
Nature Communications 6
: 7367.
14 July 2015
ROCK-isoform-specific polarization of macrophages associated with age-related macular degeneration.
Zandi, S., Nakao, S., Chun, K.H., Fiorina, P., Sun, D., Arita, R., Zhao, M., Kim, E., Schueller, O., Campbell, S., Taher, M., Melhorn, M.I., Schering, A., Gatti, F., Tezza, S., Xie, F., Vergani, A., Yoshida, S., Ishikawa, K., Yamaguchi, M., Sasaki, F., Schmidt-Ullrich, R., Hata, Y., Enaida, H., Yuzawa, M., Yokomizo, T., Kim, Y.B., Sweetnam, P., Ishibashi, T. and Hafezi-Moghadam, A.
Cell Reports 10
(7): 1173-1186.
24 February 2015
Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium.
Blackburn, J., Kawasaki, K., Porntaveetus, T., Kawasaki, M., Otsuka-Tanaka, Y., Miake, Y., Ota, M.S., Watanabe, M., Hishinuma, M., Nomoto, T., Oommen, S., Ghafoor, S., Harada, F., Nozawa-Inoue, K., Maeda, T., Peterkova, R., Lesot, H., Inoue, J., Akiyama, T., Schmidt-Ullrich, R., Liu, B., Hu, Y., Page, A., Ramirez, A., Sharpe, P.T. and Ohazama, A.
Journal of Dental Research 94
(1): 121-128.
January 2015
Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis.
Yilmaz, Z.B., Kofahl, B., Beaudette, P., Baum, K., Ipenberg, I., Weih, F., Wolf, J., Dittmar, G. and Scheidereit, C.
Cell Reports 9
(5): 1756-1769.
11 December 2014
Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, S., Bouhlel, M.A., Cauchy, P., Lamprecht, B., Li, S., Grau, M., Hummel, F., Köchert, K., Anagnostopoulos, I., Jöhrens, K., Hummel, M., Hiscott, J., Wenzel, S.S., Lenz, P., Schneider, M., Küppers, R., Scheidereit, C., Giefing, M., Siebert, R., Rajewsky, K., Lenz, G., Cockerill, P.N., Janz, M., Dörken, B., Bonifer, C. and Mathas, S.
Proceedings of the National Academy of Sciences of the United States of America 111
(42): E4513-E4522.
21 October 2014
IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai, H., Wenzel, S.S., Hailfinger, S., Grau, M., Kaergel, E., Seitz, V., Wollert-Wulf, B., Pfeifer, M., Wolf, A., Frick, M., Dietze, K., Madle, H., Tzankov, A., Hummel, M., Dörken, B., Scheidereit, C., Janz, M., Lenz, P., Thome, M. and Lenz, G.
Blood 122
(13): 2242-2250.
26 September 2013
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Lehmann, S.M., Krueger, C., Park, B., Derkow, K., Rosenberger, K., Baumgart, J., Trimbuch, T., Eom, G., Hinz, M., Kaul, D., Habbel, P., Kaelin, R., Franzoni, E., Rybak, A., Nguyen, D., Veh, R., Ninnemann, O., Peters, O., Nitsch, R., Heppner, F.L., Golenbock, D., Schott, E., Ploegh, H.L., Wulczyn, F.G. and Lehnardt, S.
Nature Neuroscience 15
(6): 827-835.
June 2012
The role of Irf6 in tooth epithelial invagination.
Blackburn, J., Ohazama, A., Kawasaki, K., Otsuka-Tanaka, Y., Liu, B., Honda, K., Rountree, R.B., Hu, Y., Kawasaki, M., Birchmeier, W., Schmidt-Ullrich, R., Kinoshita, A., Schutte, B.C., Hammond, N.L., Dixon, M.J. and Sharpe, P.T.
Developmental Biology 365
(1): 61-70.
1 May 2012
Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB.
Voutilainen, M., Lindfors, P.H., Lefebvre, S., Ahtiainen, L., Fliniaux, I., Rysti, E., Murtoniemi, M., Schneider, P., Schmidt-Ullrich, R. and Mikkola, M.L.
Proceedings of the National Academy of Sciences of the United States of America 109
(15): 5744-5749.
10 April 2012
Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations.
Jing, H., Kase, J., Dörr, J.R., Milanovic, M., Lenze, D., Grau, M., Beuster, G., Ji, S., Reimann, M., Lenz, P., Hummel, M., Doerken, B., Lenz, G., Scheidereit, C., Schmitt, C.A. and Lee, S.
Genes & Development 25
(20): 2137-2146.
15 October 2011
The prevalence of TNFα-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay.
Coel Arslan, S. and Scheidereit, C.
PLoS ONE 6
(10): e26069.
10 October 2011
Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis.
Haeaerae, O., Fujimori, S., Schmidt-Ullrich, R., Hartmann, C., Thesleff, I. and Mikkola, M.L.
Development 138
(13): 2681-2691.
July 2011
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
Hinz, M., Stilmann, M., Coel Arslan, S., Khanna, K.K., Dittmar, G. and Scheidereit, C.
Molecular Cell 40
(1): 63-74.
8 October 2010
Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.
Rauch, A., Seitz, S., Baschant, U., Schilling, A.F., Illing, A., Stride, B., Kirilov, M., Mandic, V., Takacz, A., Schmidt-Ullrich, R., Ostermay, S., Schinke, T., Spanbroek, R., Zaiss, M.M., Angel, P.E., Lerner, U.H., David, J.P., Reichardt, H.M., Amling, M., Schuetz, G. and Tuckermann, J.P.
Cell Metabolism 11
(6): 517-531.
9 June 2010
Identification of a chemokine receptor profile characteristic for mediastinal large B-cell lymphoma.
Rehm, A., Anagnostopoulos, I., Gerlach, K., Broemer, M., Scheidereit, C., Joehrens, K., Huebler, M., Hetzer, R., Stein, H., Lipp, M., Doerken, B. and Höpken, U.E.
International Journal of Cancer 125
(10): 2367-2374.
15 November 2009
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IκB kinase activation.
Stilmann, M., Hinz, M., Coel Arslan, S., Zimmer, A., Schreiber, V. and Scheidereit, C.
Molecular Cell 36
(3): 365-378.
13 November 2009
Reciprocal requirements for EDA/EDAR/NF-κB and Wnt/β-catenin signaling pathways in hair follicle induction.
Zhang, Y., Tomann, P., Andl, T., Gallant, N.M., Huelsken, J., Jerchow, B., Birchmeier, W., Paus, R., Piccolo, S., Mikkola, M.L., Morrisey, E.E., Overbeek, P.A., Scheidereit, C., Millar, S.E. and Schmidt-Ullrich, R.
Developmental Cell 17
(1): 49-61.
21 July 2009
Lef1 plays a role in patterning the mesoderm and ectoderm in Xenopus tropicalis.
Roel, G., Gent, Y.Y., Peterson-Maduro, J., Verbeek, F.J. and Destree, O.
International Journal of Developmental Biology 53
(1): 81-89.
2009
Differential RelA- and RelB-dependent gene transcription in LTbetaR-stimulated mouse embryonic fibroblasts.
Lovas, A., Radke, D., Albrecht, D., Yilmaz, Z.B., Moeller, U., Habenicht, A.J. and Weih, F.
BMC Genomics 9
: 606.
16 December 2008
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.
Zhang, Y., Andl, T., Yang, S.H., Teta, M., Liu, F., Seykora, J.T., Tobias, J.W., Piccolo, S., Schmidt-Ullrich, R., Nagy, A., Taketo, M.M., Dlugosz, A.A. and Millar, S.E.
Development 135
(12): 2161-2172.
June 2008
Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis.
Liu, F., Chu, E.Y., Watt, B., Zhang, Y., Gallant, N.M., Andl, T., Yang, S.H., Lu, M.M., Piccolo, S., Schmidt-Ullrich, R., Taketo, M.M., Morrisey, E.E., Atit, R., Dlugosz, A.A. and Millar, S.E.
Developmental Biology 313
(1): 210-224.
1 January 2008
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation.
Oeckinghaus, A., Wegener, E., Welteke, V., Ferch, U., Coel Arslan, S., Ruland, J., Scheidereit, C. and Krappmann, D.
EMBO Journal 26
(22): 4634-4645.
14 November 2007
Signal-responsiveness of Ikappa B kinases is determined by Cdc37-assisted transient interaction with Hsp90.
Hinz, M., Broemer, M., Coel Arslan, S., Otto, A., Mueller, E.C., Dettmer, R. and Scheidereit, C.
Journal of Biological Chemistry 282
(44): 32311-32319.
2 November 2007
High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis.
Weichert, W., Boehm, M., Gekeler, V., Bahra, M., Langrehr, J., Neuhaus, P., Denkert, C., Imre, G., Weller, C., Hofmann, H.P., Niesporek, S., Jacob, J., Dietel, M., Scheidereit, C. and Kristiansen, G.
British Journal of Cancer 97
: 523-530.
14 August 2007
Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage.
Henke, N., Schmidt-Ullrich, R., Dechend, R., Park, J.K., Qadri, F., Wellner, M., Obst, M., Gross, V., Dietz, R., Luft, F.C., Scheidereit, C. and Mueller, D.N.
Circulation Research 101
(3): 268-276.
3 August 2007
Striking back at the activator: how IkappaB kinase terminates antigen receptor responses.
Hinz, M. and Scheidereit, C.
Science's STKE Signal Transduction Knowledge Environment 384
: pe19.
1 May 2007
Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis.
Visekruna, A., Joeris, T., Seidel, D., Kroesen, A., Loddenkemper, C., Zeitz, M., Kaufmann, S.H.E., Schmidt-Ullrich, R. and Steinhoff, U.
Journal of Clinical Investigation 116
(12): 3195-3203.
December 2006
Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.
Wegener, E., Oeckinghaus, A., Papadopoulou, N., Lavitas, L., Schmidt-Supprian, M., Ferch, U., Mak, T.W., Ruland, J., Heissmeyer, V. and Krappmann, D.
Molecular Cell 23
(1): 13-23.
7 July 2006
NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth.
Schmidt-Ullrich, R., Tobin, D.J., Lenhard, D., Schneider, P., Paus, R. and Scheidereit, C.
Development 133
(6): 1045-1057.
15 March 2006
Viral targeting of the interferon-beta-inducing Traf family member-associated NF-kappaB activator (TANK)-binding kinase-1.
Unterstab, G., Ludwig, S., Anton, A., Planz, O., Dauber, B., Krappmann, D., Heins, G., Ehrhardt, C. and Wolff, T.
Proceedings of the National Academy of Sciences of the United States of America 102
(38): 13640-13645.
9 September 2005
Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas.
Mathas, S., Joehrens, K., Joos, S., Lietz, A., Hummel, F., Janz, M., Jundt, F., Anagnostopoulos, I., Bommert, K., Lichter, P., Stein, H., Scheidereit, C. and Doerken, B.
Blood 106
(13): 4287-4293.
25 August 2005
Regulation of vascular smooth muscle cell proliferation. Role of NF-kappaB revisited.
Mehrhof, F.B., Schmidt-Ullrich, R., Dietz, R. and Scheidereit, C.
Circulation Research 96
(9): 958-964.
1 January 2005
Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo.
Freund, C., Schmidt-Ullrich, R., Baurand, A., Dunger, S., Schneider, W., Loser, P., El-Jamali, A., Dietz, R., Scheidereit, C. and Bergmann, M.W.
Circulation 111
(18): 2319-2325.
1 January 2005
The effect of fever-like temperatures on neutrophil signaling.
Salanova, B., Choi, M., Rolle, S., Wellner, M., Scheidereit, C., Luft, F.C. and Kettritz, R.
FASEB Journal 19
(7): 816-818.
1 January 2005
Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.
Broemer, M., Krappmann, D. and Scheidereit, C.
Oncogene 23
(31): 5378-5386.
8 July 2004
The IκB kinase complex and NF-κB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1.
Krappmann, D., Wegener, E., Sunami, Y., Esen, M., Thiel, A., Mordmueller, B. and Scheidereit, C.
Molecular and Cellular Biology 24
(14): 6488-6500.
1 July 2004
Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappaB signaling.
Scharschmidt, E., Wegener, E., Heissmeyer, V., Rao, A. and Krappmann, D.
Molecular and Cellular Biology 24
(9): 3860-3873.
1 May 2004
A dual role for lkkalpha in tooth development.
Ohazama, A., Hu, Y.L., Schmidt-Ullrich, R., Cao, Y.X., Scheidereit, C., Karin, M. and Sharpe, P.T.
Developmental Cell 6
(2): 219-227.
1 January 2004
Reoxygenation after severe hypoxia induces cardiomyocyte hypertrophy in vitro: activation of CREB downstream of GSK3beta.
El Jamali, A., Freund, C., Rechner, C., Scheidereit, C., Dietz, R. and Bergmann, M.W.
FASEB Journal 18
(10): 1096-1098.
1 January 2004
Inhibition of NF-κ B by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis.
Choi, M., Rolle, S., Wellner, M., Cardoso, M.C., Scheidereit, C., Luft, F.C. and Kettritz, R.
Blood 102
(6): 2259-2267.
15 September 2003
Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis.
Mathas, S., Lietz, A., Janz, M., Hinz, M., Jundt, F., Scheidereit, C., Bommert, K. and Doerken, B.
Blood 102
(3): 1028-1034.
1 August 2003
Tetrameric oligomerization of I kappa B kinase gamma (IKK gamma) is obligatory for IKK complex activity and NF-kappa B activation.
Tegethoff, S., Behlke, J. and Scheidereit, C.
Molecular and Cellular Biology 23
(6): 2029-2041.
March 2003
Lymphotoxin and lipopolysaccharide induce NF-κB-p52 generation by a co-translational mechanism.
Mordmueller, B., Krappmann, D., Esen, M., Wegener, E. and Scheidereit, C.
EMBO Reports 4
(1): 82-87.
1 January 2003
The pathogenetic significance of deregulated signal transduction pathways in Hodgkin's disease: the NF-kappaB-AP-1 network.
Scheidereit, C.
Verhandlungen der Deutschen Gesellschaft fuer Pathologie 87
: 79-89.
1 January 2003
Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
Hinz, M., Lemke, P., Anagnostopoulos, I., Hacker, C., Krappmann, D., Mathas, S., Doerken, B., Zenke, M., Stein, H. and Scheidereit, C.
Journal of Experimental Medicine 196
(5): 605-617.
2 September 2002
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.
Mathas, S., Hinz, M., Anagnostopoulos, L., Krappmann, D., Lietz, A., Jundt, F., Bommert, K., Mechta-Grigoriou, F., Stein, H., Dörken, B. and Scheidereit, C.
EMBO Journal 21
(15): 4104-4113.
1 August 2002
Activation of cyclin D1 and D2 promoters by human T-cell leukemia virus type I tax protein is associated with IL-2-independent growth of T cells.
Mori, N., Fujii, M., Hinz, M., Nakayama, K., Yamada, Y., Ikeda, S., Yamasaki, Y., Kashanchi, F., Tanaka, Y., Tomonaga, M. and Yamamoto, N.
International Journal of Cancer 99
(3): 378-385.
20 May 2002
Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease.
Jundt, F., Kley, K., Anagnostopoulos, I., Schulze-Proebsting, K., Greiner, A., Mathas, S., Scheidereit, C., Wirth, T., Stein, H. and Doerken, B.
Blood 99
(8): 3060-3062.
15 April 2002
Purification and characterization of the human Elongator complex.
Hawkes, N.A., Otero, G., Winkler, G.S., Marshall, N., Dahmus, M.E., Krappmann, D., Scheidereit, C., Thomas, C.L., Schiavo, G., Erdjument-Bromage, H., Tempst, P. and Svejstrup, J.Q.
Journal of Biological Chemistry 277
(4): 3047-3052.
1 January 2002
Up-regulation of the chemokine receptor CCR7 in classical but not in lymphocyte-predominant Hodgkin disease correlates with distinct dissemination of neoplastic cells in lymphoid organs.
Höpken, U.E., Foss, H.D., Meyer, D., Hinz, M., Leder, K., Stein, H. and Lipp, M.
Blood 99
(4): 1109-1116.
1 January 2002
Nitric oxide synthase 2Lambarene (G-954C), increased nitric oxide production, and protection against malaria.
Kun, J.F., Mordmueller, B., Perkins, D.J., May, J., Mercereau-Puijalon, O., Alpers, M., Weinberg, J.B. and Kremsner, P.G.
Journal of Infectious Diseases 184
(3): 330-336.
1 August 2001
The MAPK kinase kinase TAK1 plays a central role in coupling the interleukin-1 receptor to both transcriptional and RNA-targeted mechanisms of gene regulation.
Holtmann, H., Enninga, J., Kalble, S., Thiefes, A., Dorrie, A., Broemer, M., Winzen, R., Wilhelm, A., Ninomiya-Tsuji, J., Matsumoto, K., Resch, K. and Kracht, M.
Journal of Biological Chemistry 276
: 3508-3516.
2 February 2001
Aspirin inhibits NF-kappa B and protects from angiotensin II-induced organ damage.
Mueller, D.N., Heissmeyer, V., Dechend, R., Hampich, F., Park, J.K., Fiebeler, A., Shagdarsuren, E., Theuer, J., Elger, M., Pilz, B., Breu, V., Schroer, K., Ganten, D., Dietz, R., Haller, H., Scheidereit, C. and Luft, F.C.
FASEB Journal 15
: 1822-1824.
1 January 2001
B-cell receptor- and phorbol ester-induced NF-kappa B and c-Jun N-terminal kinase activation in B cells requires novel protein kinase C's.
Krappmann, D., Patke, A., Heissmeyer, V. and Scheidereit, C.
Molecular and Cellular Biology 21
: 6640-6650.
1 January 2001
Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.
Hinz, M., Loeser, P., Mathas, S., Krappmann, D., Dörken, B. and Scheidereit, C.
Blood 97
(9): 2798-2807.
1 January 2001
In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein.
Mehrhof, F.B., Mueller, F.U., Bergmann, M.W., Li, P.F., Wang, Y.B., Schmitz, W., Dietz, R. and von Harsdorf, R.
Circulation 104
: 2088-2094.
1 January 2001
In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappaB activity.
Wuchter, C., Krappmann, D., Cai, Z., Ruppert, V., Scheidereit, C., Doerken, B., Ludwig, W.D. and Karawajew, L.
Leukemia 15
(6): 921-928.
1 January 2001
Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices.
Schmidt-Ullrich, R., Aebischer, T., Huelsken, J., Birchmeier, W., Klemm, U. and Scheidereit, C.
Development 128
(19): 3843-3853.
1 January 2001
Shared pathways of IkappaB kinase-induced SCF betaTrCP-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and I kappa B alpha.
Heissmeyer, V., Krappmann, D., Hatada, E.N. and Scheidereit, C.
Molecular and Cellular Biology 21
(4): 1024-1035.
1 January 2001
Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia.
Slaugenhaupt, S.A., Blumenfeld, A., Gill, S.P., Leyne, M., Mull, J., Cuajungco, M.P., Liebert, C.B., Chadwick, B., Idelson, M., Reznik, L., Robbins, C.M., Makalowska, I., Brownstein, M.J., Krappmann, D., Scheidereit, C., Maayan, C., Axelrod, F.B. and Gusella, J.F.
American Journal of Human Genetics 68
: 598-605.
1 January 2001
Promoter variants of the human mannose-binding lectin gene show different binding.
Jueliger, S., Luckner, D., Mordmueller, B., May, J., Weierich, A., Lell, B., Luty, A., Kremsner, P.G. and Kun, J.F.
Biochemical and Biophysical Research Communications 275
: 617-622.
28 August 2000
In vivo identification of lymphocyte subsets exhibiting transcriptionally active NF-kappaB/Rel complexes.
Feuillard, J., Memet, S., Goudeau, B., Lilienbaum, A., Schmidt-Ullrich, R., Raphael, M. and Israel, A.
International Immunology 12
(5): 613-621.
May 2000
Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex.
Hehner, S.P., Hofmann, T.G., Ushmorov, A., Dienz, O., Leung, I.W.L., Lassam, N., Scheidereit, C., Droege, W. and Schmitz, M.L.
Molecular and Cellular Biology 20
: 2556-2568.
1 April 2000
Cutaneous inflammation and proliferation in vitro: Differential effects and mode of action of topical glucocorticoids.
Lange, K., Kleuser, B., Gysler, A., Bader, M., Maia, C., Scheidereit, C., Korting, H.C. and Schaefer-Korting, M.
Skin Pharmacology and Applied Skin Physiology 13
(2): 93-103.
1 March 2000
Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells.
Kordes, U., Krappmann, D., Heissmeyer, V., Ludwig, W.D. and Scheidereit, C.
Leukemia 14
(3): 399-402.
March 2000
Anti-CD20-and B-cell receptor-mediated apoptosis: Evidence for shared intracellular signaling pathways.
Mathas, S., Rickers, A., Bommert, K., Doerken, B. and Mapara, M.Y.
Cancer Research 60
(24): 7170-7176.
1 January 2000
Interaction and functional interference of C/EBPbeta with octamer factors in immunoglobulin gene transcription.
Hatada, E.N., Chen-Kiang, S. and Scheidereit, C.
European Journal of Immunology 30
(1): 174-184.
1 January 2000
The IkappaB kinase (IKK) complex is tripartiteand contains IKKgamma but not IKAP as a regular component.
Krappmann, D., Hatada, E.N., Tegethoff, S., Li, J., Klippel, A., Giesel, K., Baeuerle, A. and Scheidereit, C.
Journal of Biological Chemistry 275
: 29779-29787.
1 January 2000
Overexpression of IkappaBalpha without inhibition of NF-kappaB activity and mutations in the IkappaBalpha gene in Reed-Sternberg cells.
Emmerich, F., Meiser, M., Hummel, M., Demel, G., Foss, H.D., Jundt, F., Mathas, S., Krappmann, D., Scheidereit, C., Stein, H. and Dörken, B.
Blood 94
: 3129-3134.
1 November 1999
Chlamydia pneumoniae infection of vascular smooth muscle and endothelial cells activates NF-kappaB and induces tissue factor and PAI-1 expression - A potential link to accelerated arteriosclerosis.
Dechend, R., Maass, M., Gieffers, J., Dietz, R., Scheidereit, C., Leutz, A. and Gulba, D.C.
Circulation 100
: 1369-1373.
28 September 1999
NF-kappaB p105 is a target of I kappaB kinases and controls signal induction of Bcl-3-p50 complexes.
Heissmeyer, V., Krappmann, D., Wulczyn, F.G. and Scheidereit, C.
EMBO Journal 18
: 4766-4778.
1 September 1999
E2F-1 overexpression in cardiomyocytes induces downregulation of p21CIP1 and p27KIP1 and release of active cyclin-dependent kinases in the presence of insulin-like growth factor I.
von Harsdorf, R., Hauck, L., Mehrhof, F., Wegenka, U., Cardoso, M.C. and Dietz, R.
Circulation Research 85
: 128-136.
23 July 1999
The Bcl-3 oncoprotein acts as a bridging factor between NF-kappa B/Rel and nuclear co-regulators.
Dechend, R., Hirano, F., Lehmann, K., Heissmeyer, V., Ansieau, S., Wulczyn, F.G., Scheidereit, C. and Leutz, A.
Oncogene 18
: 3316-3323.
3 June 1999
NF-kappaB function in growth control: Regulation of cyclin D1 expression and G(0)G(1)-to-S-Phase transition.
Hinz, M., Krappmann, D., Eichten, A., Heder, A., Scheidereit, C. and Strauss, M.
Molecular and Cellular Biology 19
: 2690-2698.
1 April 1999
Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.
Krappmann, D., Emmerich, F., Kordes, U., Scharschmidt, E., Doerken, B. and Scheidereit, C.
Oncogene 18
: 943-953.
28 January 1999
Neutrophils and monocytes from subjects with the Mediterranean G6PD variant: effect of Plasmodium falciparum hemozoin on G6PD activity, oxidative burst and cytokine production.
Mordmueller, B., Turrini, F., Long, H., Kremsner, P.G. and Arese, P.
European Cytokine Network 9
: 239-245.
1 September 1998
Alternative splicing variants of IkappaBbeta establish differential NF-kappaB signal responsiveness in human cells.
Hirano, F., Chung, M.R., Tanaka, H., Maruyama, N., Makino, I., Moore, D.D. and Scheidereit, C.
Molecular and Cellular Biology 18
(5): 2596-2607.
May 1998
Hyperparasitemia and blood exchange transfusion for treatment of children with falciparum malaria.
Mordmueller, B. and Kremsner, P.G.
Clinical Infectious Diseases 26
: 850-852.
1 April 1998
Signal-dependent degradation of IkappaBalpha is mediated by an inducible destruction box that can be transferred to NF-kappaB, bcl-3 or p53.
Wulczyn, F.G., Krappmann, D. and Scheidereit, C.
Nucleic Acids Research 26
(7): 1724-1730.
1 April 1998
Inhibition of NF-kappaB-dependent transcription of human immunodeficiency virus 1 promoter by a phosphodiester compound of vitamin C and vitamin E, EPC-K1.
Hirano, F., Tanaka, H., Miura, T., Hirano, Y., Okamoto, K., Makino, Y. and Makino, I.
Immunopharmacology 39
: 31-38.
1 March 1998
Functional interference of Sp1 and NF-kappaB through the same DNA binding site.
Hirano, F., Tanaka, H., Hirano, Y., Hiramoto, M., Handa, H., Makino, I. and Scheidereit, C.
Molecular and Cellular Biology 18
(3): 1266-1274.
March 1998
Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria.
Kun, J.F., Mordmueller, B., Lell, B., Lehman, L.G., Luckner, D. and Kremsner, P.G.
Lancet 351
(9098): 265-266.
24 January 1998
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.
Bargou, R.C., Emmerich, F., Krappmann, D., Bommert, K., Mapara, M.Y., Arnold, W., Royer, H.D., Grinstein, E., Greiner, A., Scheidereit, C. and Doerken, B.
Journal of Clinical Investigation 100
(12): 2961-2969.
15 December 1997
Efficient transcription of an immunoglobulin kappa promoter requires specific sequence elements overlapping with and downstream of the transcriptional start site.
Pelletier, M.R., Hatada, E.N., Scholz, G. and Scheidereit, C.
Nucleic Acids Research 25
(20): 3995-4003.
15 October 1997
Tumor necrosis factor in Plasmodium falciparum malaria: high plasma level is associated with fever, but high production capacity is associated with rapid fever clearance.
Mordmueller, B.G., Metzger, W.G., Juillard, P., Brinkman, B.M., Verweij, C.L., Grau, G.E. and Kremsner, P.G.
European Cytokine Network 8
: 29-35.
1 March 1997
Regulation of NF-kappa B activity by I kappa B alpha and I kappa B beta stability.
Krappmann, D. and Scheidereit, C.
Immunobiology 198
: 3-13.
1 January 1997
The role of oxygen metabolism for the pathological phenotype of fanconi anemia.
Ruppitsch, W., Meisslitzer, C., Weirichschwaiger, H., Klocker, H., Scheidereit, C., Schweiger, M. and Hirschkauffmann, M.
Human Genetics 99
: 710-719.
1 January 1997
Different mechanisms control signal-induced degradation and basal turnover of the NF-kappab inhibitor ikappabalpha in vivo.
Krappmann, D., Wulczyn, F.G. and Scheidereit, C.
EMBO Journal 15
(23): 6716-6726.
2 December 1996
NF-kappaB activity in transgenic mice: developmental regulation and tissue specificity.
Schmidt-Ullrich, R., Memet, S., Lilienbaum, A., Feuillard, J., Raphael, M. and Israel, A.
Development 122
(7): 2117-2128.
July 1996
High level nuclear NF-kB and Oct-2 is a common feature of cultured Hodgkin/Sternberg cells.
Bargou, R.C., Leng, C., Krappmann, D., Emmerich, F., Mapara, M.Y., Bommert, K., Royer, H.D., Scheidereit, C. and Doerken, B.
Blood 87
(10): 4340-4347.
1 January 1996
Sequence-specific recognition of a repetitive DNA element by a C2H2 zinc-finger protein in Xenopus.
Schafer, U., Rausch, O., Bouwmeester, T. and Pieler, T.
European Journal of Biochemistry 226
: 567-576.
1 December 1994
Activation of NF-kappaB in vivo is regulated by multiple phosphorylations.
Naumann, M. and Scheidereit, C.
EMBO Journal 13
(19): 4597-4607.
3 October 1994
Identification of novel ubiquitous and cell type-specific factors that specifically recognize immunoglobulin heavy and light chain promoters.
Franke, S., Scholz, G. and Scheidereit, C.
Journal of Biological Chemistry 269
(31): 20075-20082.
5 August 1994
Functional aspects of B-Myb in early Xenopus development.
Bouwmeester, T., van Wijk, I., Wedlich, D. and Pieler, T.
Oncogene 9
(4): 1029-1038.
April 1994
The FAR domain defines a new Xenopus laevis zinc finger protein subfamily with specific RNA homopolymer binding activity.
Klocke, B., Koester, M., Hille, S., Bouwmeester, T., Boehm, S., Pieler, T. and Knoechel, W.
Biochimica et Biophysica Acta 1217
: 81-89.
1 January 1994
NF-kappaB precursor p100 inhibits nuclear translocation and DNA binding of NF-kappaB/rel-factors.
Naumann, M., Nieters, A., Hatada, E.N. and Scheidereit, C.
Oncogene 8
(8): 2275-2281.
1 August 1993
Common structural constituents confer IkappaB activity to NF-kappaB p105 and IkappaB/MAD-3.
Hatada, E.N., Naumann, M. and Scheidereit, C.
EMBO Journal 12
(7): 2781-2788.
July 1993
The NF-kappaB precursor p105 and the proto-oncogene product Bcl- 3 are I kappa B molecules and control nuclear translocation of NF-kappa B.
Naumann, M., Wulczyn, F.G. and Scheidereit, C.
EMBO Journal 12
(1): 213-222.
January 1993
Transcriptional regulation of the HIV-1 promoter by NF-kappa B in vitro.
Kretzschmar, M., Meisterernst, M., Scheidereit, C., Li, G. and Roeder, R.G.
Genes & Development 6
(5): 761-774.
May 1992
Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappaB.
Wulczyn, F.G., Naumann, M. and Scheidereit, C.
Nature 358
(6387): 597-599.
1 January 1992
The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappaB DNA binding.
Hatada, E.N., Nieters, A., Wulczyn, F.G., Naumann, M., Meyer, R., Nucifora, G., McKeithan, T.W. and Scheidereit, C.
Proceedings of the National Academy of Sciences of the United States of America 89
(6): 2489-2493.
1 January 1992
Book Section
ANCA-associated vasculitis and the mechanisms of tissue injury.
Schreiber, A. and Choi, M.
In:
Systemic Vasculitides: Current Status and Perspectives.
Springer, Cham, 141-158.
ISBN 978-3-319-40134-8
14 October 2016
NF-κB pathway.
Scheidereit, C. and Krappmann, D.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2.
Springer, Berlin [u.a.], 1286-1292.
ISBN 3-540-44244-8
2006
Thesis
Modulierung der NF-kappaB-Aktivitaet in T-Zellen durch den Carmal1-Bcl10-Malt1 Komplex.
Wegener, E.
UNSPECIFIED thesis, UNSPECIFIED.
4 July 2006
Patent
Genetisch veraendertes, nicht-menschliches Saeugetier, das ein zusaetzliches induzierbares Regulator-Gen enthaelt [Genetically modified, non-human mammal containing an additional inducible regulator gene].
Scheidereit, C. and Schmidt-Ullrich, R.
DE10041842A1 ; WO0216573.
7 March 2002
Review
The IκB kinase complex in NF-κB regulation and beyond.
Hinz, M. and Scheidereit, C.
EMBO Reports 15
(1): 46-61.
1 January 2014
Novel signalling mechanisms and targets in renal ischaemia and reperfusion injury.
Kusch, A., Hoff, U., Bubalo, G., Zhu, Y., Fechner, M., Schmidt-Ullrich, R., Marko, L., Müller, D.N., Schmidt-Ott, K.M., Gürgen, D., Blum, M., Schunck, W.H. and Dragun, D.
Acta Physiologica 208
(1): 25-40.
May 2013
Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: an update.
Nakamura, M., Schneider, M.R., Schmidt-Ullrich, R. and Paus, R.
Journal of Dermatological Science 69
(1): 6-29.
January 2013
It takes two to tango: IκBs, the multifunctional partners of NF-κB.
Hinz, M., Coel Arslan, S. and Scheidereit, C.
Immunological Reviews 246
(1): 59-76.
March 2012
The hair follicle as a dynamic miniorgan.
Schneider, M.R., Schmidt-Ullrich, R. and Paus, R.
Current Biology 19
(3): R132-T142.
10 February 2009
IkappaB kinase complexes: gateways to NF-kappaB activation and transcription.
Scheidereit, C.
Oncogene 25
(51): 6685-6705.
30 October 2006
Molecular principles of hair follicle induction and morphogenesis.
Schmidt-Ullrich, R. and Paus, R.
BioEssays 27
(3): 247-261.
15 February 2005
A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways.
Krappmann, D. and Scheidereit, C.
EMBO Reports 6
(4): 321-326.
1 January 2005
NF-kappaB and the innate immune response.
Hatada, E.N., Krappmann, D. and Scheidereit, C.
Current Opinion in Immunology 12
: 52-58.
1 February 2000
The NF-kappaB/Rel and IkappaB gene families: mediators of immune response and inflammation.
Wulczyn, F.G., Krappmann, D. and Scheidereit, C.
Journal of Molecular Medicine 74
: 749-769.
1 January 1996
Letter
NF-κB activity is required for anagen maintenance in human hair follicles in vitro.
Kloepper, J.E., Ernst, N., Krieger, K., Bodo, E., Biro, T., Haslam, I.S., Schmidt-Ullrich, R. and Paus, R.
Journal of Investigative Dermatology 134
(7): 2036-2038.
11 February 2014
Editorial
Signal transduction. Docking IkappaB kinases.
Scheidereit, C.
Nature 395
: 225-226.
17 September 1998
Transcription factors: important tools and targets for molecular medicine.
Scheidereit, C.
Journal of Molecular Medicine 74
: 707-709.
1 January 1996
Preprint
Autophagy limits inflammatory gene expression through targeting of nuclear p65/RelA by LC3 and p62 for lysosomal degradation.
Brischetto, C., Mucka, P., Kaergel, E. and Scheidereit, C.
bioRxiv
: 2022.11.02.514846.
2 November 2022
This list was generated on Mon Oct 7 02:02:22 2024 UTC.