2026

Workload-induced changes to cell state contribute to β-cell failure in diabetes.
Sai, Somesh ORCID: https://orcid.org/0000-0001-6865-341X, Liu, Fenfen, Harrington, Austin R., Zhu, Han, Omar, Ibrahim, Zeng, Chun, Mallick, Medhavi, Sui, Yinghui, Sander, Maike ORCID: https://orcid.org/0000-0001-5308-7785 and Wortham, Matthew ORCID: https://orcid.org/0009-0003-1302-4167
bioRxiv : 2026.05.13.725004. 18 May 2026

The AICL-KLRF1 axis supports CD4-CD8 T cell communication and cytokine competence in pre-exhausted CD8(+) T cells.
Barone, Matthias ORCID: https://orcid.org/0000-0002-6554-6464, Peidli, Stefan ORCID: https://orcid.org/0000-0002-4257-8690, Neuschulz, Anika ORCID: https://orcid.org/0000-0001-6163-3344, Riesterer, Karla, Iwert, Christina, Junquera, Laia ORCID: https://orcid.org/0009-0006-9259-0213, Sai, Somesh ORCID: https://orcid.org/0000-0001-6865-341X, Bolaji, Olufemi, Bakoueva, Diana, Appelt, Christine ORCID: https://orcid.org/0009-0000-7865-9911, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Klinger, Bertram ORCID: https://orcid.org/0000-0003-0242-1506, Trinks, Alexandra ORCID: https://orcid.org/0000-0001-9983-1506, Sieber, Anja ORCID: https://orcid.org/0000-0001-6588-8547, Blüthgen, Nils ORCID: https://orcid.org/0000-0002-0171-7447 and Sawitzki, Birgit ORCID: https://orcid.org/0000-0001-8166-8579
EMBO Reports 27 (8): 2029-2060. 27 April 2026

The AICL-KLRF1 axis supports CD4-CD8 T cell communication and cytokine competence in pre-exhausted CD8+ T cells.
Barone, Matthias ORCID: https://orcid.org/0000-0002-6554-6464, Peidli, Stefan ORCID: https://orcid.org/0000-0002-4257-8690, Neuschulz, Anika ORCID: https://orcid.org/0000-0001-6163-3344, Riesterer, Karla, Iwert, Christina, Junquera, Laia, Sai, Somesh ORCID: https://orcid.org/0000-0001-6865-341X, Bolaji, Olufemi, Bakoueva, Diana, Appelt, Christine, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Klinger, Bertram ORCID: https://orcid.org/0000-0003-0242-1506, Trinks, Alexandra ORCID: https://orcid.org/0000-0001-9983-1506, Sieber, Anja, Blüthgen, Nils ORCID: https://orcid.org/0000-0002-0171-7447 and Sawitzki, Birgit
[Dataset] 6 March 2026

2025

Antithrombin-binding heparan sulfate is ubiquitously expressed in epithelial cells and suppresses pancreatic tumorigenesis.
Clausen, Thomas Mandel, Weiss, Ryan J., Tremblay, Jacob R., Kellman, Benjamin P., Coker, Joanna, Dworkin, Leo A., Rodriguez, Jessica P., Chang, Ivy M, Chen, Timothy, Padala, Vikram, Karlsson, Richard, Song, Hyemin, Peck, Kristina L., Ogawa, Satoshi, Sandoval, Daniel R., Joshi, Hiren J., Wang, Gaowei, Ferguson, L. Paige, Bhalerao, Nikita, Moores, Allison, Reya, Tannishtha, Sander, Maike ORCID: https://orcid.org/0000-0001-5308-7785, Caffrey, Thomas C., Grem, Jean L., Aicher, Alexandra, Heeschen, Christopher, Le, Dzung, Lewis, Nathan E., Hollingsworth, Michael A., Grandgenett, Paul M., Bellis, Susan L., Miller, Rebecca L., Fuster, Mark M., Dawson, David W., Engle, Dannielle D. and Esko, Jeffrey D.
Journal of Clinical Investigation 135 (22): e184172. 17 November 2025

The protein deacetylase SIRT2 exerts metabolic control over adaptive β cell proliferation.
Wortham, Matthew, Ramms, Bastian, Zeng, Chun, Benthuysen, Jacqueline R., Sai, Somesh ORCID: https://orcid.org/0000-0001-6865-341X, Pollow, Dennis P., Liu, Fenfen, Schlichting, Michael, Harrington, Austin R., Liu, Bradley, Prakash, Thazha P., Pirie, Elaine C., Zhu, Han, Baghdasarian, Siyouneh, Lee, Sean T., Ruthig, Victor A., Wells, Kristen L., Auwerx, Johan, Shirihai, Orian S. and Sander, Maike ORCID: https://orcid.org/0000-0001-5308-7785
Journal of Clinical Investigation 135 (19): e187020. 1 October 2025

A vascular-associated fibroblastic cell controls pancreatic islet immunity.
Clarke, Don, Costanzo, Anne, Sharma, Siddhartha, Kain, Lisa, Moremen, Kelley W., Pettus, Jeremy, Domissy, Alain, Wu, Peng, Nguyen-Ngoc, Kim-Vy, Berti, Denise, George, Steven C., Hughes, Christopher C.W., Sander, Maike ORCID: https://orcid.org/0000-0001-5308-7785 and Teyton, Luc
Cell Reports 44 (9): 116189. 23 September 2025

Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids.
Jun, Yesl, Nguyen-Ngoc, Kim-Vy, Sai, Somesh ORCID: https://orcid.org/0000-0001-6865-341X, Bender, R. Hugh F., Gong, Winnie, Kravets, Vira, Zhu, Han, Hatch, Christopher J., Schlichting, Michael, Gaetani, Roberto, Mallick, Medhavi, Hachey, Stephanie J., Christman, Karen L., George, Steven C., Hughes, Christopher C.W. and Sander, Maike ORCID: https://orcid.org/0000-0001-5308-7785
Developmental Cell 60 (18): 2455-2469.e7. 22 September 2025

Single-cell multiome and spatial profiling reveals pancreas cell type-specific gene regulatory programs of type 1 diabetes progression.
Melton, Rebecca, Jimenez, Sara, Elison, Weston, Tucciarone, Luca, Howell, Abigail, Wang, Gaowei, Berti, Denise, Beebe, Elisha, Miller, Michael, Zeng, Chun, McGrail, Carolyn, VanderStel, Kennedy, Korgaonkar, Katha, Elgamal, Ruth, Mummey, Hannah, Chiou, Joshua, Griffin, Emily, Kusmartseva, Irina, Atkinson, Mark, Preissl, Sebastian, Theis, Fabian J., Sander, Maike ORCID: https://orcid.org/0000-0001-5308-7785 and Gaulton, Kyle J.
Science Advances 11 (37): eady0080. 12 September 2025

Single-cell multiome and spatial profiling reveals pancreas cell type-specific gene regulatory programs driving type 1 diabetes progression.
Melton, Rebecca ORCID: https://orcid.org/0000-0003-3219-5773, Jimenez, Sara, Elison, Weston ORCID: https://orcid.org/0000-0002-5496-2972, Tucciarone, Luca ORCID: https://orcid.org/0000-0002-0142-2171, Howell, Abigail, Wang, Gaowei, Berti, Denise, Beebe, Elisha, Miller, Michael, Zeng, Chun, McGrail, Carolyn, VanderStel, Kennedy, Korgaonkar, Katha, Elgamal, Ruth ORCID: https://orcid.org/0000-0001-9183-9386, Mummey, Hannah ORCID: https://orcid.org/0000-0002-7663-8559, Chiou, Joshua ORCID: https://orcid.org/0000-0002-4618-0647, Griffin, Emily, Kusmartseva, Irina ORCID: https://orcid.org/0000-0003-2614-0813, Atkinson, Mark ORCID: https://orcid.org/0000-0001-8489-4782, Preissl, Sebastian ORCID: https://orcid.org/0000-0001-8971-5616, Theis, Fabian ORCID: https://orcid.org/0000-0002-2419-1943, Sander, Maike ORCID: https://orcid.org/0000-0001-5308-7785 and Gaulton, Kyle ORCID: https://orcid.org/0000-0003-1318-7161
[Dataset] 3 July 2025

The IsletTester mouse: an immunodeficient model with stable hyperglycemia for the study of human islets.
Waite, E.L., Tigue, M., Yu, M., Lahori, D., Kelly, K., May, C.L., Naji, A., Roman, J., Doliba, N., Avrahami, D., Nguyen-Ngoc, K.V., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Glaser, B. and Kaestner, K.H.
Diabetes 74 (3): 332-342. March 2025

Spatial profiling of human pancreas during type 1 diabetes progression.
Jiménez, Sara ORCID: https://orcid.org/0000-0001-7103-7474, Sander, Maike ORCID: https://orcid.org/0000-0001-5308-7785, Theis, Fabian ORCID: https://orcid.org/0000-0002-2419-1943 and Gaulton, Kyle ORCID: https://orcid.org/0000-0003-1318-7161
[Dataset] 14 February 2025

2024

Integration of CTCF loops, methylome, and transcriptome in differentiating LUHMES as a model for imprinting dynamics of the 15q11-q13 locus in human neurons.
Gutierrez Fugón, O.J., Sharifi, O., Heath, N., Soto, D.C. ORCID: https://orcid.org/0000-0002-6292-655X, Gomez, J.A., Yasui, D.H., Mendiola, A.J.P., O'Geen, He., Beitnere, U. ORCID: https://orcid.org/0000-0002-5597-7092, Tomkova, M., Haghani, V., Dillon, G., Segal, D.J. and LaSalle, J.M.
Human Molecular Genetics 33 (19): 1711-1725. 1 October 2024

Atypical KCNQ1/Kv7 channel function in a neonatal diabetes patient: hypersecretion preceded the failure of pancreatic β-cells.
Zhou, Z., Gong, M. ORCID: https://orcid.org/0000-0001-7384-3429, Pande, A. ORCID: https://orcid.org/0009-0008-0826-973X, Margineanu, A. ORCID: https://orcid.org/0000-0002-6634-9729, Lisewski, U., Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Zhu, H., Liang, L., Jia, S. ORCID: https://orcid.org/0000-0001-8595-9314, Froehler, S. ORCID: https://orcid.org/0000-0001-8000-2927, Zeng, C., Kühnen, P. ORCID: https://orcid.org/0000-0003-0211-176X, Khodaverdi, S., Krill, W., Röpke, T., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Raile, K. ORCID: https://orcid.org/0000-0002-0842-1737, Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Izsvák, Z. ORCID: https://orcid.org/0000-0002-2053-2384
iScience 27 (7): 110291. 19 July 2024

EU-LIFE charter of independent life science research institutes.
Superti-Furga, G. ORCID: https://orcid.org/0000-0002-0570-1768, Agostinho, M., Bury, J., Cook, S., Durinx, C., Ender, A., van Luenen, H., Lund, A.H., Medema, R.H., Miączyńska, M., Nickel, D., Pelicci, P.G., Puisieux, A., Ripatti, S., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Schubeler, D., Serrano, L., Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202, Sonne-Hansen, K., Tomančák, P., Vives, J., Vontas, J. and Bettencourt-Dias, M.
FEBS Letters 598 (7): 719-724. April 2024

A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction.
Bender, R.H.F., O'Donnell, B.T. ORCID: https://orcid.org/0000-0002-3529-231X, Shergill, B., Pham, B.Q., Tahmouresie, S., Sanchez, C.N., Juat, D.J., Hatch, M.M.S., Shirure, V.S., Wortham, M., Nguyen-Ngoc, K.V., Jun, Y., Gaetani, R., Christman, K.L., Teyton, L., George, S.C., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Hughes, C.C.W.
Biofabrication 16 (2): 025001. 11 January 2024

2023

Gene editing to improve pancreatic beta cell yield in directed differentiation of human pluripotent stem cells.
The regents of the university of California.
WO-2023137235-A3. 20 July 2023

Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding.
Urizar, A.I. ORCID: https://orcid.org/0000-0003-3672-1910, Prause, M., Ingerslev, L.R. ORCID: https://orcid.org/0000-0002-4164-7690, Wortham, M., Sui, Y., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Williams, K., Barrès, R., Larsen, M.R., Christensen, G.L. and Billestrup, N. ORCID: https://orcid.org/0000-0002-4968-8067
Cell Death & Disease 14 (7): 399. 5 July 2023

Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes.
Wang, G., Chiou, J. ORCID: https://orcid.org/0000-0002-4618-0647, Zeng, C., Miller, M., Matta, I., Han, J.Y. ORCID: https://orcid.org/0000-0002-4035-7915, Kadakia, N. ORCID: https://orcid.org/0000-0002-1884-1671, Okino, M.L., Beebe, E., Mallick, M., Camunas-Soler, J. ORCID: https://orcid.org/0000-0001-6148-8132, Dos Santos, T. ORCID: https://orcid.org/0000-0002-9761-3609, Dai, X.Q., Ellis, C., Hang, Y., Kim, S.K. ORCID: https://orcid.org/0000-0001-6135-7810, MacDonald, P.E., Kandeel, F.R., Preissl, S. ORCID: https://orcid.org/0000-0001-8971-5616, Gaulton, K.J. ORCID: https://orcid.org/0000-0003-1318-7161 and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Nature Genetics 55 (6): 984-994. June 2023

Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes.
Zhu, H., Wang, G., Nguyen-Ngoc, K.V., Kim, D., Miller, M., Goss, G., Kovsky, J., Harrington, A.R., Saunders, D.C., Hopkirk, A.L., Melton, R., Powers, A.C., Preissl, S., Spagnoli, F.M., Gaulton, K.J. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Developmental Cell 58 (9): 727-743. 8 May 2023

Nutrient regulation of the islet epigenome controls adaptive insulin secretion.
Wortham, M., Liu, F., Harrington, A.R., Fleischman, J.Y., Wallace, M., Mulas, F., Mallick, M., Vinckier, N.K., Cross, B.R., Chiou, J., Patel, N.A., Sui, Y., McGrail, C., Jun, Y., Wang, G., Jhala, U.S., Schüle, R., Shirihai, O.S., Huising, M.O., Gaulton, K.J., Metallo, C.M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Journal of Clinical Investigation 133 (8): e165208. 17 April 2023

Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors.
Magenheim, J., Maestro, M.A., Sharon, N., Herrera, P.L., Murtaugh, L.C., Kopp, J., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Gu, G., Melton, D.A., Ferrer, J. ORCID: https://orcid.org/0000-0002-5959-5729 and Dor, Y. ORCID: https://orcid.org/0000-0003-2456-2289
Cell Stem Cell 30 (4): 488-497. 6 April 2023

The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.
Costanzo, M.C., von Grotthuss, M., Massung, J., Jang, D., Caulkins, L., Koesterer, R., Gilbert, C., Welch, R.P., Kudtarkar, P., Hoang, Q., Boughton, A.P., Singh, P., Sun, Y., Duby, M., Moriondo, A., Nguyen, T., Smadbeck, P., Alexander, B.R., Brandes, M.K., Carmichael, M., Dornbos, P., Green, T., Huellas-Bruskiewicz, K.C., Ji, Y., Kluge, A., McMahon, A.C., Mercader, J.M., Ruebenacker, O., Sengupta, S., Spalding, D., Taliun, D., Smith, P., Thomas, M.K., Akolkar, B., Brosnan, M.J., Cherkas, A., Chu, A.Y., Fauman, E.B., Fox, C.S., Kamphaus, T.N., Miller, M.R., Nguyen, L., Parsa, A., Reilly, D.F., Ruetten, H., Wholley, D., Zaghloul, N.A., Abecasis, G.R., Altshuler, D., Keane, T.M., McCarthy, M.I., Gaulton, K.J., Florez, J.C., Boehnke, M., Burtt, N.P. and Flannick, J.
Cell Metabolism 35 (4): 695-710.e6. 4 April 2023

Integrated physiology of the exocrine and endocrine compartments in pancreatic diseases: workshop proceedings.
Mastracci, T.L. ORCID: https://orcid.org/0000-0003-1956-1951, Apte, M., Amundadottir, L.T., Alvarsson, A., Artandi, S., Bellin, M.D., Bernal-Mizrachi, E., Caicedo, A., Campbell-Thompson, M., Cruz-Monserrate, Z., El Ouaamari, A., Gaulton, K.J., Geisz, A., Goodarzi, M.O., Hara, M., Hull-Meichle, R.L., Kleger, A., Klein, A.P., Kopp, J.L., Kulkarni, R.N., Muzumdar, M.D., Naren, A.P., Oakes, S.A., Olesen, S.S., Phelps, E.A., Powers, A.C., Stabler, C.L., Tirkes, T., Whitcomb, D.C., Yadav, D., Yong, Jing, Zaghloul, N.A., Pandol, S.J. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Diabetes 72 (4): 433-448. April 2023

2022

Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.
Benaglio, P., Zhu, H., Okino, M.L., Yan, J., Elgamal, R., Nariai, N., Beebe, E., Korgaonkar, K., Qiu, Y., Donovan, M.K.R., Chiou, J., Wang, G., Newsome, J., Kaur, J., Miller, M., Preissl, S., Corban, S., Aylward, A., Taipale, J., Ren, B., Frazer, K.A., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Gaulton, K.J.
Cell Genomics 2 (12): 100214. 14 December 2022

Systemic LSD1 inhibition prevents aberrant remodeling of metabolism in obesity.
Ramms, B., Pollow, D.P., Zhu, H., Nora, C., Harrington, A.R., Omar, I., Gordts, P.L.S.M., Wortham, M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Diabetes 71 (12): 2513-2529. December 2022

Integrated physiology of the exocrine and endocrine compartments in pancreatic diseases.
Mastracci, T.L., Apte, M., Amundadottir, L.T., Alvarsson, A., Artandi, S., Bellin, M.D., Bernal-Mizrachi, E., Caicedo, A., Campbell-Thompson, M., Cruz-Monserrate, Z., El Ouaamari, A., Gaulton, K.J., Geisz, A., Goodarzi, M.O., Hara, M., Hull-Meichle, R.L., Kleger, A., Klein, A.P., Kopp, J.L., Kulkarni, R.N., Muzumdar, M.D., Naren, A.P., Oakes, S.A., Olesen, S.S., Phelps, E.A., Powers, A.C., Stabler, C.L., Tirkes, T., Whitcomb, D.C., Yadav, D., Yong, J., Zaghloul, N.A., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Pandol, S.J.
Pancreas 51 (9): 1061-1073. 1 October 2022

Every islet matters: improving the impact of human islet research.
Gloyn, Anna L ORCID: https://orcid.org/0000-0003-1205-1844, Ibberson, Mark ORCID: https://orcid.org/0000-0003-3152-5670, Marchetti, Piero, Powers, Alvin C ORCID: https://orcid.org/0000-0003-1941-5786, Rorsman, Patrik ORCID: https://orcid.org/0000-0001-7578-0767, Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Solimena, Michele
Nature Metabolism 4 (8): 970-977. August 2022

Sizing up beta cells made from stem cells.
Nguyen-Ngoc, K.V., Wortham, M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Nature Biotechnology 40 (7): 1006-1008. July 2022

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Mahajan, A., Spracklen, C.N., Zhang, W., Ng, M.C.Y., Petty, L.E., Kitajima, H., Yu, G.Z., Rüeger, S., Speidel, L., Kim, Y.J., Horikoshi, M., Mercader, J.M., Taliun, D., Moon, S., Kwak, S.H., Robertson, N.R., Rayner, N.W., Loh, M., Kim, B.J., Chiou, J., Miguel-Escalada, I., Della Briotta Parolo, P., Lin, K., Bragg, F., Preuss, M.H., Takeuchi, F., Nano, J., Guo, X., Lamri, A., Nakatochi, M., Scott, R.A., Lee, J.., Huerta-Chagoya, A., Graff, M., Chai, J.F., Parra, E.J., Yao, J., Bielak, L.F., Tabara, Y., Hai, Y., Steinthorsdottir, V., Cook, J.P., Kals, M., Grarup, N., Schmidt, E.M., Pan, I., Sofer, T., Wuttke, M., Sarnowski, C., Gieger, C., Nousome, D., Trompet, S., Long, J., Sun, M., Tong, L., Chen, W.M., Ahmad, M., Noordam, R., Lim, V.J.Y., Tam, C.H.T., Joo, Y.Y., Chen, C.H., Raffield, L.M., Lecoeur, C., Prins, B.P., Nicolas, A., Yanek, L.R., Chen, G., Jensen, R.A., Tajuddin, S., Kabagambe, E.K., An, P., Xiang, A.H., Choi, H.S., Cade, B.E., Tan, J., Flanagan, J., Abaitua, F., Adair, L.S., Adeyemo, A., Aguilar-Salinas, C.A., Akiyama, M., Anand, S.S., Bertoni, A., Bian, Z., Bork-Jensen, J., Brandslund, I., Brody, J.A., Brummett, C.M., Buchanan, T.A., Canouil, M., Chan, J.C.N., Chang, L.C., Chee, M.L., Chen, J., Chen, S.H., Chen, Y.T., Chen, Z., Chuang, L.M., Cushman, M., Das, S.K., de Silva, H.J., Dedoussis, G., Dimitrov, L., Doumatey, A.P., Du, S., Duan, Q., Eckardt, K.U., Emery, L.S., Evans, D.S., Evans, M.K., Fischer, K., Floyd, J.S., Ford, I., Fornage, M., Franco, O.H., Frayling, T.M., Freedman, B.I., Fuchsberger, C., Genter, P., Gerstein, H.C., Giedraitis, V., González-Villalpando, C., González-Villalpando, M.E., Goodarzi, M.O., Gordon-Larsen, P., Gorkin, D., Gross, M., Guo, Y., Hackinger, S., Han, S., Hattersley, A.T., Herder, C., Howard, A.G., Hsueh, W., Huang, M., Huang, W., Hung, Y.J., Hwang, M.Y., Hwu, C.M., Ichihara, S., Ikram, M.A., Ingelsson, M., Islam, M.T., Isono, M., Jang, H.M., Jasmine, F., Jiang, G., Jonas, J.B., Jørgensen, M.E., Jørgensen, T., Kamatani, Y., Kandeel, F.R., Kasturiratne, A., Katsuya, T., Kaur, V., Kawaguchi, T., Keaton, J.M., Kho, A.N., Khor, C.C., Kibriya, M.G., Kim, D.H., Kohara, K., Kriebel, J., Kronenberg, F., Kuusisto, J., Läll, K., Lange, L.A., Lee, M.S., Lee, N.R., Leong, A., Li, L., Li, Y., Li-Gao, R., Ligthart, S., Lindgren, C.M., Linneberg, A., Liu, C.T., Liu, J., Locke, A.E., Louie, T., Luan, J., Luk, A.O., Luo, X., Lv, J., Lyssenko, V., Mamakou, V., Mani, K.R., Meitinger, T., Metspalu, A., Morris, A.D., Nadkarni, G.N., Nadler, J.L., Nalls, M.A., Nayak, U., Nongmaithem, S.S., Ntalla, I., Okada, Y., Orozco, L., Patel, S.R., Pereira, M.A., Peters, A., Pirie, F.J., Porneala, B., Prasad, G., Preissl, S., Rasmussen-Torvik, L.J., Reiner, A.P., Roden, M., Rohde, R., Roll, K., Sabanayagam, C., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Sandow, K., Sattar, N., Schönherr, S., Schurmann, C., Shahriar, M., Shi, J., Shin, D.M., Shriner, D., Smith, J.A., So, W.Y., Stančáková, A., Stilp, A.M., Strauch, K., Suzuki, K., Takahashi, A., Taylor, K.D., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tomlinson, B., Torres, J.M., Tsai, F.J., Tuomilehto, J., Tusie-Luna, T., Udler, M.S., Valladares-Salgado, A., van Dam, R.M., van Klinken, J.B., Varma, R., Vujkovic, M., Wacher-Rodarte, N., Wheeler, E., Whitsel, E.A., Wickremasinghe, A.R., van Dijk, K.W., Witte, D.R., Yajnik, C.S., Yamamoto, K., Yamauchi, T., Yengo, L., Yoon, K., Yu, C., Yuan, J.M., Yusuf, S., Zhang, L., Zheng, W., Raffel, L.J., Igase, M., Ipp, E., Redline, S., Cho, Y.S., Lind, L., Province, M.A., Hanis, C.L., Peyser, P.A., Ingelsson, E., Zonderman, A.B., Psaty, B.M., Wang, Y.X., Rotimi, C.N., Becker, D.M., Matsuda, F., Liu, Y., Zeggini, E., Yokota, M., Rich, S.S., Kooperberg, C., Pankow, J.S., Engert, J.C., Chen, Y.D.I., Froguel, P., Wilson, J.G., Sheu, W.H.H., Kardia, S.L.R., Wu, J.Y., Hayes, M.G., Ma, R.C.W., Wong, T.Y., Groop, L., Mook-Kanamori, D.O., Chandak, G.R., Collins, F.S., Bharadwaj, D., Paré, G., Sale, M.M., Ahsan, H., Motala, A.A., Shu, X.O., Park, K.S., Jukema, J.W., Cruz, M., McKean-Cowdin, R., Grallert, H., Cheng, C.Y., Bottinger, E.P., Dehghan, A., Tai, E.S., Dupuis, J., Kato, N., Laakso, M., Köttgen, A., Koh, W.P., Palmer, C.N A., Liu, S., Abecasis, G., Kooner, J.S., Loos, R.J.F., North, K.E., Haiman, C.A., Florez, J.C., Saleheen, D., Hansen, T., Pedersen, O., Mägi, R., Langenberg, C., Wareham, N.J., Maeda, S., Kadowaki, T., Lee, J., Millwood, I.Y., Walters, R.G., Stefansson, K., Myers, S.R., Ferrer, J., Gaulton, K.J., Meigs, J.B., Mohlke, K.L., Gloyn, A.L., Bowden, D.W., Below, J.E., Chambers, J.C., Sim, X., Boehnke, M., Rotter, J.I., McCarthy, M.I. and Morris, A.P.
Nature Genetics 54 (5): 560-572. May 2022

Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance.
Shum, M., Segawa, M., Gharakhanian, R., Viñuela, A., Wortham, M., Baghdasarian, S., Wolf, D.M., Sereda, S.B., Nocito, L., Stiles, L., Zhou, Z., Gutierrez, V., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Shirihai, O.S. and Liesa, M.
Molecular Metabolism 55 : 101403. January 2022

Heterogeneity of diabetes: β-cells, phenotypes, and precision medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
Cefalu, W.T., Andersen, D.K., Arreaza-Rubín, G., Pin, C.L., Sato, S., Verchere, C.B., Woo, M. and Rosenblum, N.D.
Diabetes 71 (1): 1–22. January 2022

2021

Heterogeneity of diabetes: β-cells, phenotypes, and precision medicine: proceedings of an international symposium of the canadian institutes of Health Research’s Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases.
Cefalu, W.T., Andersen, D.K., Arreaza-Rubín, G., Pin, C.L., Sato, S., Verchere, C.B., Woo, M., Rosenblum, N.D., Rosenblum, N., Cefalu, W., Andersen, D.K., Arreaza-Rubín, G., Dhara, C., James, S.P., Makarchuk, M.J., Pin, C.L., Sato, S., Verchere, B., Woo, M., Powers, A., Estall, J., Hoesli, C., Millman, J., Linnemann, A., Johnson, J., Pin, C.L., Hawkins, M., Woo, M., Gloyn, A., Cefalu, W., Rosenblum, N., Huising, M.O., Benninger, R.K.P., Almaça, J., Hull-Meichle, R.L., MacDonald, P., Lynn, F., Melero-Martin, J., Yoshihara, E., Stabler, C., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Evans-Molina, C., Engin, F., Thompson, P., Shalev, A., Redondo, M.J., Nadeau, K., Bellin, M., Udler, M.S., Dennis, J., Dash, S., Zhou, W., Snyder, M., Booth, G., Butte, A. and Florez, J.
Canadian Journal of Diabetes 45 (8): 697-713. December 2021

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.
Geusz, R.J. ORCID: https://orcid.org/0000-0002-4897-9305, Wang, A., Lam, D.K., Vinckier, N.K., Alysandratos, K.D., Roberts, D.A., Wang, J., Kefalopoulou, S., Ramirez, A., Qiu, Y. ORCID: https://orcid.org/0000-0002-0539-9714, Chiou, J. ORCID: https://orcid.org/0000-0002-4618-0647, Gaulton, K.J. ORCID: https://orcid.org/0000-0003-1318-7161, Ren, B. ORCID: https://orcid.org/0000-0002-5435-1127, Kotton, D.N. ORCID: https://orcid.org/0000-0002-9604-8476 and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Nature Communications 12 (1): 6636. 17 November 2021

Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation.
Heller, S., Li, Z., Lin, Q., Geusz, R., Breunig, M., Hohwieler, M., Zhang, X., Nair, G.G., Seufferlein, T., Hebrok, M., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Julier, C., Kleger, A. and Costa, I.G.
Communications Biology 4 (1): 1298. 17 November 2021

A multi-omics roadmap of β-cell failure in type 2 diabetes mellitus.
Wang, G. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Nature Reviews Endocrinology 17 (11): 641-642. November 2021

Mutations and variants of ONECUT1 in diabetes.
Philippi, A., Heller, S. ORCID: https://orcid.org/0000-0002-8704-2646, Costa, I.G. ORCID: https://orcid.org/0000-0003-2890-8697, Senée, V. ORCID: https://orcid.org/0000-0001-7012-3944, Breunig, M. ORCID: https://orcid.org/0000-0002-2817-1974, Li, Z., Kwon, G. ORCID: https://orcid.org/0000-0002-4269-6638, Russell, R., Illing, A., Lin, Q., Hohwieler, M. ORCID: https://orcid.org/0000-0002-0640-0764, Degavre, A., Zalloua, P. ORCID: https://orcid.org/0000-0002-8494-5081, Liebau, S., Schuster, M. ORCID: https://orcid.org/0000-0003-2975-8969, Krumm, Jo., Zhang, X. ORCID: https://orcid.org/0000-0001-6485-4564, Geusz, R., Benthuysen, J. R., Wang, A., Chiou, J. ORCID: https://orcid.org/0000-0002-4618-0647, Gaulton, K. ORCID: https://orcid.org/0000-0003-1318-7161, Neubauer, H., Simon, E., Klein, T., Wagner, M. ORCID: https://orcid.org/0000-0001-5735-3462, Nair, G., Besse, C., Dandine-Roulland, C., Olaso, R., Deleuze, J.F., Kuster, B. ORCID: https://orcid.org/0000-0002-9094-1677, Hebrok, M., Seufferlein, T., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Boehm, B.O. ORCID: https://orcid.org/0000-0002-2706-7710, Oswald, F., Nicolino, M., Julier, C. ORCID: https://orcid.org/0000-0002-1538-0240 and Kleger, A. ORCID: https://orcid.org/0000-0003-0592-5232
Nature Medicine 27 (11): 1928-1940. November 2021

What is a β cell? - Chapter I in the Human Islet Research Network (HIRN) review series.
Kaestner, K.H., Campbell-Thompson, M., Dor, Y., Gill, R.G., Glaser, B., Kim, S.K., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Stabler, C., Stewart, A.F. and Powers, A.C.
Molecular Metabolism 53 : 101323. November 2021

Career advancement for women in diabetes-related research: developing and retaining female talent.
Sandoval, D.A., Alonso, L.C., Gannon, M., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Sussel, L. and Reusch, J.E.B.
Diabetes 70 (8): 1634-1637. 1 August 2021

Career advancement for women in diabetes-related research: developing and retaining female talent.
Sandoval, D.A. ORCID: https://orcid.org/0000-0003-3669-3278, Alonso, L.C. ORCID: https://orcid.org/0000-0001-5056-8970, Gannon, M. ORCID: https://orcid.org/0000-0003-3287-8101, Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Sussel, L. and Reusch, J.E.B. ORCID: https://orcid.org/0000-0001-8620-1003
Diabetes Care 44 (8): 1744-1747. August 2021

Transcriptional mechanisms of pancreatic β-cell maturation and functional adaptation.
Wortham, M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Trends in Endocrinology and Metabolism 32 (7): 474-487. July 2021

Interpreting type 1 diabetes risk with genetics and single-cell epigenomics.
Chiou, J. ORCID: https://orcid.org/0000-0002-4618-0647, Geusz, R.J., Okino, M.L., Han, J.Y., Miller, M., Melton, R., Beebe, E., Benaglio, P., Huang, S., Korgaonkar, K., Heller, S. ORCID: https://orcid.org/0000-0002-8704-2646, Kleger, A. ORCID: https://orcid.org/0000-0003-0592-5232, Preissl, S., Gorkin, D.U., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Gaulton, K.J. ORCID: https://orcid.org/0000-0003-1318-7161
Nature 594 (7863): 398-402. 17 June 2021

Transformation of SOX9(+) cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma.
Chen, J., Debebe, A., Zeng, N., Kopp, J., He, L., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Stiles, B.L.
Scientific Reports 11 (1): 11823. 3 June 2021

Single-cell chromatin accessibility identifies pancreatic islet cell type- and state-specific regulatory programs of diabetes risk.
Chiou, J., Zeng, C., Cheng, Z., Han, J.Y., Schlichting, M., Miller, M., Mendez, R., Huang, S., Wang, J., Sui, Y., Deogaygay, A., Okino, M.L., Qiu, Y., Sun, Y., Kudtarkar, P., Fang, R., Preissl, S., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Gorkin, D.U. and Gaulton, K.J.
Nature Genetics 53 (4): 455-466. April 2021

Systematic analysis of binding of transcription factors to noncoding variants.
Yan, J., Qiu, Y., Ribeiro Dos Santos, A.M., Yin, Y., Li, Y.E., Vinckier, N., Nariai, N., Benaglio, P., Raman, A., Li, X., Fan, S., Chiou, J., Chen, F., Frazer, K.A., Gaulton, K.J., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Taipale, Ju. and Ren, B.
Nature 591 (7848): 147-151. March 2021

Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development.
Geusz, R.J. ORCID: https://orcid.org/0000-0002-4897-9305, Wang, A. ORCID: https://orcid.org/0000-0001-9870-7888, Chiou, J. ORCID: https://orcid.org/0000-0002-4618-0647, Lancman, J.J. ORCID: https://orcid.org/0000-0003-1238-4446, Wetton, N., Kefalopoulou, S., Wang, J., Qiu, Y. ORCID: https://orcid.org/0000-0002-0539-9714, Yan, J. ORCID: https://orcid.org/0000-0002-1267-2870, Aylward, A. ORCID: https://orcid.org/0000-0003-3524-856X, Ren, B., Dong, P.D.S., Gaulton, K.J. ORCID: https://orcid.org/0000-0003-1318-7161 and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
eLife 10 : e59067. 5 February 2021

Inferring time series chromatin states for promoter-enhancer pairs based on Hi-C data.
Miko, H. ORCID: https://orcid.org/0000-0001-5911-7586, Qiu, Y., Gaertner, B., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
BMC Genomics 22 (1): 84. 28 January 2021

2020

A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation.
Gaertner, B., van Heesch, S. ORCID: https://orcid.org/0000-0001-9593-1980, Schneider-Lunitz, V. ORCID: https://orcid.org/0000-0002-3980-3789, Schulz, J.F. ORCID: https://orcid.org/0000-0002-8157-2224, Witte, F., Blachut, S. ORCID: https://orcid.org/0009-0007-0102-9867, Nguyen, S., Wong, R., Matta, I., Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223 and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
eLife 9 : e58659. 3 August 2020

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.
Vinckier, N.K., Patel, N.A., Geusz, R.J. ORCID: https://orcid.org/0000-0002-4897-9305, Wang, A., Wang, J., Matta, I., Harrington, A.R., Wortham, M., Wetton, N., Wang, J., Jhala, U.S., Rosenfeld, M.G. ORCID: https://orcid.org/0000-0002-1572-156X, Benner, C.W. ORCID: https://orcid.org/0000-0002-4618-0719, Shih, H.P. ORCID: https://orcid.org/0000-0003-3035-5841 and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Nature Communications 11 (1): 2082. 29 April 2020

PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response.
Ye, J., Huang, A., Wang, H., Zhang, A.M.Y., Huang, X., Lan, Q., Sato, T., Goyama, S., Kurokawa, M., Deng, C., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Schaeffer, D.F., Li, W., Kopp, J.L. and Xie, R.
Cell death and disease 11 (3): 187. 16 March 2020

2019

A network of microRNAs acts to promote cell cycle exit and differentiation of human pancreatic endocrine cells.
Jin, W., Mulas, F., Gaertner, B., Sui, Y., Wang, J., Matta, I., Zeng, C., Vinckier, N., Wang, A., Nguyen-Ngoc, K.V., Chiou, J., Kaestner, K.H., Frazer, K.A., Carrano, A.C., Shih, H.P. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
iScience 21 : 681-694. 22 November 2019

Human stem cell models: lessons for pancreatic development and disease.
Gaertner, B., Carrano, A.C. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Genes & Development 33 (21-22): 1475-1490. 1 November 2019

In vivo-mimicking microfluidic perfusion culture of pancreatic islet spheroids.
Jun, Y. ORCID: https://orcid.org/0000-0002-7598-9226, Lee, J.S. ORCID: https://orcid.org/0000-0002-5797-8021, Choi, S. ORCID: https://orcid.org/0000-0003-1813-1626, Yang, J.H. ORCID: https://orcid.org/0000-0002-8582-9285, Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Chung, S. ORCID: https://orcid.org/0000-0002-1735-8338 and Lee, S.H.
Science Advances 5 (11): eaax4520. 1 November 2019

Differential cell susceptibilities to kras(G12D) in the setting of obstructive chronic pancreatitis.
Shi, C., Pan, F.C., Kim, J.N., Washington, M.K., Padmanabhan, C., Meyer, C.T., Kopp, J.L., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Gannon, M., Beauchamp, R.D., Wright, C.V. and Means, A.L.
Cellular and molecular gastroenterology and hepatology 8 (4): 579-594. 31 October 2019

Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifications.
Ibarra Urizar, A., Prause, M., Wortham, M., Sui, Y., Thams, P., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Christensen, G.L. and Billestrup, N.
Molecular and Cellular Endocrinology 496 : 110524. 1 October 2019

Nomenclature for cellular plasticity: are the terms as plastic as the cells themselves?
Mills, J.C. ORCID: https://orcid.org/0000-0002-0402-4662, Stanger, B.Z. ORCID: https://orcid.org/0000-0003-0410-4037 and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
EMBO Journal 38 (19): e103148. 1 October 2019

Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk.
Greenwald, W.W., Chiou, J. ORCID: https://orcid.org/0000-0002-4618-0647, Yan, J., Qiu, Y. ORCID: https://orcid.org/0000-0002-0539-9714, Dai, N., Wang, A., Nariai, N., Aylward, A., Han, J.Y., Kadakia, N. ORCID: https://orcid.org/0000-0002-1884-1671, Regue, L., Okino, M.L., Drees, F., Kramer, D., Vinckier, N., Minichiello, L. ORCID: https://orcid.org/0000-0002-4246-4765, Gorkin, D. ORCID: https://orcid.org/0000-0003-4944-4107, Avruch, J., Frazer, K.A., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Ren, B. ORCID: https://orcid.org/0000-0002-5435-1127 and Gaulton, K.J. ORCID: https://orcid.org/0000-0003-1318-7161
Nature Communications 10 (1): 2078. 7 May 2019

Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma.
Lee, A.Y.L., Dubois, C.L., Sarai, K., Zarei, S., Schaeffer, D.F., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Kopp, J. L.
Gut 68 (3): 487-498. March 2019

2018

Integrated in vivo quantitative proteomics and nutrient tracing reveals age-related metabolic rewiring of pancreatic β cell function.
Wortham, M., Benthuysen, J.R., Wallace, M., Savas, J.N., Mulas, F., Divakaruni, A.S., Liu, F., Albert, V., Taylor, B.L., Sui, Y., Saez, E., Murphy, A.N., Yates, J.R., Metallo, C.M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Cell Reports 25 (10): 2904-2918. 4 December 2018

Evaluation of different decellularization protocols on the generation of pancreas-derived hydrogels.
Gaetani, R., Aude, S., DeMaddalena, L.L., Strassle, H., Dzieciatkowska, M., Wortham, M., Bender, R.H.F., Nguyen-Ngoc, K.V., Schmid-Schöenbein, G.W., George, S.C., Hughes, C.C.W., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Hansen, K.C. and Christman, K.L.
Tissue Engineering Part C Methods 24 (12): 697-708. December 2018

N(6)-methyladenine DNA modification in glioblastoma.
Xie, Q., Wu, T.P., Gimple, R.C., Li, Z., Prager, B.C., Wu, Q., Yu, Y., Wang, P., Wang, Y., Gorkin, D.U., Zhang, C., Dowiak, A.V., Lin, K., Zeng, C., Sui, Y., Kim, L.J.Y., Miller, T.E., Jiang, L., Lee, C.H., Huang, Z. ORCID: https://orcid.org/0000-0002-8993-4912, Fang, X.., Zhai, K., Mack, S.C., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Bao, S., Kerstetter-Fogle, A.E., Sloan, A.E., Xiao, A.Z. and Rich, J.N.
Cell 175 (5): 1228-1243. 15 November 2018

Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon(+) α-cells.
Cigliola, V., Ghila, L. ORCID: https://orcid.org/0000-0001-7173-6312, Thorel, F., van Gurp, L., Baronnier, D., Oropeza, D., Gupta, S., Miyatsuka, T., Kaneto, H., Magnuson, M.A. ORCID: https://orcid.org/0000-0002-8824-6499, Osipovich, A.B., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Wright, C.E.V., Thomas, M.K., Furuyama, K., Chera, S. and Herrera, P.L. ORCID: https://orcid.org/0000-0003-0771-9504
Nature Cell Biology 20 (11): 1267-1277. November 2018

Epigenetics and epigenomics: implications for diabetes and obesity.
Rosen, E.D., Kaestner, K.H., Natarajan, R., Patti, M.E., Sallari, R., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Susztak, K.
Diabetes 67 (10): 1923-1931. 1 October 2018

Pancreatic exocrine tissue architecture and integrity are maintained by e-cadherin during postnatal development.
Serrill, J.D., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Shih, H.P. ORCID: https://orcid.org/0000-0003-3035-5841
Scientific Reports 8 (1): 13451. 7 September 2018

ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis.
Das, K.K., Heeg, S., Pitarresi, J.R., Reichert, M., Bakir, B., Takano, S., Kopp, J.L., Wahl-Feuerstein, A., Hicks, P., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Rustgi, A.K. ORCID: https://orcid.org/0000-0002-6439-6919
Developmental Dynamics 247 (6): 854-866. June 2018

Loss of pten and activation of kras synergistically induce formation of intraductal papillary mucinous neoplasia from pancreatic ductal cells in mice.
Kopp, J.L., Dubois, C.L., Schaeffer, D.F., Samani, A., Taghizadeh, F., Cowan, R.W., Rhim, A.D., Stiles, B.L., Valasek, M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Gastroenterology 154 (5): 1509-1523.e5. April 2018

2017

The 4D nucleome project.
Dekker, J., Belmont, A.S., Guttman, M., Leshyk, V.O., Lis, J.T., Lomvardas, S., Mirny, L.A., O'Shea, C.C., Park, P.J., Ren, B., Politz, J.C.R., Shendure, J. and Zhong, S.
Nature 549 (7671): 219-226. 14 September 2017

Interrogating islets in health and disease with single-cell technologies.
Carrano, A.C., Mulas, F., Zeng, C. ORCID: https://orcid.org/0000-0001-9034-7873 and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Molecular Metabolism 6 (9): 991-1001. September 2017

Pseudotemporal ordering of single cells reveals metabolic control of postnatal ß cell proliferation.
Zeng, C., Mulas, F., Sui, Y., Guan, T., Miller, N., Tan, Y., Liu, F., Jin, W., Carrano, A.C., Huising, M.O., Shirihai, O.S., Yeo, G.W. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Cell Metabolism 25 (5): 1160-1175.e11. 2 May 2017

LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.
Ediger, B.N., Lim, H.W., Juliana, C., Groff, D.N., Williams, L.T., Dominguez, G., Liu, J.H., Taylor, B.L., Walp, E.R., Kameswaran, V., Yang, J., Liu, C., Hunter, C.S., Kaestner, K.H., Naji, A., Li, C., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Stein, R., Sussel, L., Won, K.J., May, C.L. and Stoffers, D.A.
Journal of Clinical Investigation 127 (1): 215-229. 3 January 2017

2016

Advances in β cell replacement and regeneration strategies for treating diabetes.
Benthuysen, J.R., Carrano, A.C. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Journal of Clinical Investigation 126 (10): 3651-3660. 3 October 2016

Mechanisms of β-cell functional adaptation to changes in workload.
Wortham, M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Diabetes Obesity & Metabolism 18 (Suppl 1): 78-86. September 2016

Pancreatic differentiation from human pluripotent stem cells.
Vinckier, N., Wang, J. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
In: Working with stem cells. Springer, Cham, 257-275. ISBN 978-3-319-30580-6 5 August 2016

Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration.
Barrionuevo, F.J., Hurtado, A. ORCID: https://orcid.org/0000-0001-6267-704X, Kim, G.J., Real, F.M., Bakkali, M., Kopp, J.L., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Scherer, G., Burgos, M. and Jiménez, R.
eLife 5 : e15635. 21 June 2016

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.
Fox, R.G., Lytle, N.K., Jaquish, D.V., Park, F.D., Ito, T., Bajaj, J., Koechlein, C.S., Zimdahl, B., Yano, M., Kopp, J., Kritzik, M., Sicklick, J., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Grandgenett, P.M., Hollingsworth, M.A., Shibata, S., Pizzo, D., Valasek, M., Sasik, R., Scadeng, M., Okano, H., Kim, Y., MacLeod, A.R., Lowy, A.M. and Reya, T.
Nature 534 (7607): 407-411. 16 June 2016

High T gives β cells a boost.
Wortham, M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Cell Metabolism 23 (5): 761-3. 10 May 2016

Stem cells versus plasticity in liver and pancreas regeneration.
Kopp, J.L., Grompe, M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Nature Cell Biology 18 (3): 238-45. March 2016

ECM signaling regulates collective cellular dynamics to control pancreas branching morphogenesis.
Shih, H.P., Panlasigui, D., Cirulli, V. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Cell Reports 14 (2): 169-79. 12 January 2016

2015

A gene regulatory network cooperatively controlled by Pdx1 and Sox9 governs lineage allocation of foregut progenitor cells.
Shih, H.P., Seymour, P.A., Patel, N.A., Xie, R., Wang, A., Liu, P.P., Yeo, G.W., Magnuson, M.A. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Cell Reports 13 (2): 326-36. 13 October 2015

Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus.
Thélie, A., Desiderio, S., Hanotel, J., Quigley, I., Van Driessche, B., Rodari, A., Borromeo, M.D., Kricha, S., Lahaye, F., Croce, J., Cerda-Moya, G., Ordoño Fernandez, J., Bolle, B., Lewis, K.E., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Pierani, A., Schubert, M., Johnson, J.E., Kintner, C.R., Pieler, T., Van Lint, C., Henningfeld, K.A., Bellefroid, E.J. and Van Campenhout, C.
Development 142 (19): 3416-28. 1 October 2015

Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer.
Font-Burgada, J., Shalapour, S., Ramaswamy, S., Hsueh, B., Rossell, D., Umemura, A., Taniguchi, K., Nakagawa, H., Valasek, M.A., Ye, L., Kopp, J.L., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Carter, H., Deisseroth, K., Verma, I.M. and Karin, M.
Cell 162 (4): 766-79. 13 August 2015

Lineage fate of ductular reactions in liver injury and carcinogenesis.
Jörs, S., Jeliazkova, P., Ringelhan, M., Thalhammer, J., Dürl, S., Ferrer, J., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Heikenwalder, M., Schmid, R.M., Siveke, J.T. and Geisler, F.
Journal of Clinical Investigation 125 (6): 2445-57. 1 June 2015

Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates.
Wang, A., Yue, F., Li, Y., Xie, R., Harper, T., Patel, N.A., Muth, K., Palmer, J., Qiu, Y., Wang, J., Lam, D.K., Raum, J.C., Stoffers, D.A., Ren, B. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Cell Stem Cell 16 (4): 386-99. 2 April 2015

Postnatal β-cell proliferation and mass expansion is dependent on the transcription factor Nkx6.1.
Taylor, B.L., Benthuysen, J. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Diabetes 64 (3): 897-903. 1 March 2015

Hnf1b controls pancreas morphogenesis and the generation of Ngn3(+) endocrine progenitors.
De Vas, M.G., Kopp, J.L., Heliot, C., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Cereghini, S. and Haumaitre, C.
Development 142 (5): 871-82. March 2015

A systems view of epigenetic networks regulating pancreas development and β-cell function.
Xie, R., Carrano, A.C. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Wiley Interdisciplinary Reviews Systems Biology and Medicine 7 (1): 1-11. 19 February 2015

2014

The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells.
Malhotra, G.K., Zhao, X., Edwards, E., Kopp, J.L., Naramura, M., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Band, H. and Band, V.
BMC Developmental Biology 14 : 47. 20 December 2014

Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor.
Kanda, S., Tanigawa, S., Ohmori, T., Taguchi, A., Kudo, K., Suzuki, Y., Sato, Y., Hino, S., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Perantoni, A.O., Sugano, S., Nakao, M. and Nishinakamura, R.
Journal of the American Society of Nephrology 25 (11): 2584-95. November 2014

Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor.
Zhao, X., Chen, Y., Zhu, Q., Huang, H., Teng, P., Zheng, K., Hu, X., Xie, B., Zhang, Z., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Qiu, M.
PLoS ONE 9 (10): e109171. 6 October 2014

Stem cell epigenetics: looking forward.
Benitah, S.A., Bracken, A., Dou, Y., Huangfu, D., Ivanova, N., Koseki, H., Laurent, L., Lim, D.A., Meshorer, E., Pombo, A. ORCID: https://orcid.org/0000-0002-7493-6288, Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Xu, G.L.
Cell Stem Cell 14 (6): 706-709. 5 June 2014

Pancreas development ex vivo: culturing embryonic pancreas explants on permeable culture inserts, with fibronectin-coated glass microwells, or embedded in three-dimensional Matrigel(TM).
Shih, H.P. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Methods in Molecular Biology 1210 : 229-37. 1 January 2014

New insights into the cell lineage of pancreatic ductal adenocarcinoma: evidence for tumor stem cells in premalignant lesions?
Kopp, J.L. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Gastroenterology 146 (1): 24-6. January 2014

2013

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.
Rockich, B.E., Hrycaj, S.M., Shih, H.P., Nagy, M.S., Ferguson, M.A.H., Kopp, J.L., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Wellik, D.M. and Spence, J.R.
Proceedings of the National Academy of Sciences of the United States of America 110 (47): E4456-64. 19 November 2013

Pancreas organogenesis: from lineage determination to morphogenesis.
Shih, H.P., Wang, A. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Annual Review of Cell and Developmental Biology 29 : 81-105. October 2013

Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells.
Taylor, B.L., Liu, F.F. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Cell Reports 4 (6): 1262-75. 26 September 2013

Inactivation of specific β cell transcription factors in type 2 diabetes.
Guo, S., Dai, C., Guo, M., Taylor, B., Harmon, J.S., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Robertson, R.P., Powers, A.C. and Stein, R.
Journal of Clinical Investigation 123 (8): 3305-16. August 2013

Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel.
Jin, L., Feng, T., Shih, H.P., Zerda, R., Luo, A., Hsu, J., Mahdavi, A., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Tirrell, D.A., Riggs, A.D. and Ku, H.T.
Proceedings of the National Academy of Sciences of the United States of America 110 (10): 3907-12. 5 March 2013

Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells.
Xie, R., Everett, L.J., Lim, H.W., Patel, N.A., Schug, J., Kroon, E., Kelly, O.G., Wang, A., D'Amour, K.A., Robins, A.J., Won, K.J., Kaestner, K.H. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Cell Stem Cell 12 (2): 224-37. 7 February 2013

Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.
Schaffer, A.E., Taylor, B.L., Benthuysen, J.R., Liu, J., Thorel, F., Yuan, W., Jiao, Y., Kaestner, K.H., Herrera, P.L., Magnuson, M.A., May, C.L. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
PLoS Genetics 9 (1): e1003274. 31 January 2013

2012

Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells.
van der Meulen, T., Xie, R., Kelly, O.G., Vale, W.W., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Huising, M.O.
PLoS ONE 7 (12): e52181. 14 December 2012

Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma.
Kopp, J.L., von Figura, G., Mayes, E., Liu, F.F., Dubois, C.L., Morris, J.P., Pan, F.C., Akiyama, H., Wright, C.V.E., Jensen, K., Hebrok, M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Cancer Cell 22 (6): 737-50. 11 December 2012

Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes.
Morán, I., Akerman, I., van de Bunt, M., Xie, R., Benazra, M., Nammo, T., Arnes, L., Nakić, N., García-Hurtado, J., Rodríguez-Seguí, S., Pasquali, L., Sauty-Colace, C., Beucher, A., Scharfmann, R., van Arensbergen, J., Johnson, P.R., Berry, A., Lee, C., Harkins, T., Gmyr, V., Pattou, F., Kerr-Conte, J., Piemonti, L., Berney, T., Hanley, N., Gloyn, A.L., Sussel, L., Langman, L., Brayman, K.L., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, McCarthy, M.I., Ravassard, P. and Ferrer, J.
Cell Metabolism 16 (4): 435-48. 3 October 2012

A Sox9/Fgf feed-forward loop maintains pancreatic organ identity.
Seymour, P.A., Shih, H.P., Patel, N.A., Freude, K.K., Xie, R., Lim, C.J. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Development 139 (18): 3363-72. September 2012

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.
Shih, H.P., Kopp, J.L., Sandhu, M., Dubois, C.L., Seymour, P.A., Grapin-Botton, A. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Development 139 (14): 2488-99. July 2012

Generating cells of the gastrointestinal system: current approaches and applications for the differentiation of human pluripotent stem cells.
Wang, A. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Journal of Molecular Medicine 90 (7): 763-71. July 2012

2011

Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance.
Schaffer, A.E., Yang, A.J., Thorel, F., Herrera, P.L. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Molecular Endocrinology 25 (11): 1904-14. 1 November 2011

Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells.
Carpentier, R., Suñer, R.E., van Hul, N., Kopp, J.L., Beaudry, J.B., Cordi, S., Antoniou, A., Raynaud, P., Lepreux, S., Jacquemin, P., Leclercq, I.A., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Lemaigre, F.P.
Gastroenterology 141 (4): 1432-8, 1438.e1-4. October 2011

Sox9-haploinsufficiency causes glucose intolerance in mice.
Dubois, C.L., Shih, H.P., Seymour, P.A., Patel, N.A., Behrmann, J.M., Ngo, V. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
PLoS ONE 6 (8): e23131. 2 August 2011

Progenitor cell domains in the developing and adult pancreas.
Kopp, J.L., Dubois, C.L., Hao, E., Thorel, F., Herrera, P.L. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Cell Cycle 10 (12): 1921-7. 15 June 2011

Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice.
Dorrell, C., Erker, L., Schug, J., Kopp, J.L., Canaday, P.S., Fox, A.J., Smirnova, O., Duncan, A.W., Finegold, M.J., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Kaestner, K.H. and Grompe, M.
Genes & Development 25 (11): 1193-203. 1 June 2011

Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development.
Seymour, P.A. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Diabetes 60 (2): 364-76. 1 February 2011

Sox9(+) ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.
Kopp, J.L., Dubois, C.L., Schaffer, A.E., Hao, E., Shih, H.P., Seymour, P.A., Ma, J. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Development 138 (4): 653-65. February 2011

2010

Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.
Schaffer, A.E., Freude, K.K., Nelson, S.B. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Developmental Cell 18 (6): 1022-9. 15 June 2010

2009

Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain.
Prakash, N., Puelles, E., Freude, K., Trümbach, D., Omodei, D., Di Salvio, M., Sussel, L., Ericson, J., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Simeone, A. and Wurst, W.
Development 136 (15): 2545-55. August 2009

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function.
Wang, S., Jensen, J.N., Seymour, P.A., Hsu, W., Dor, Y., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Magnuson, M.A., Serup, P. and Gu, G.
Proceedings of the National Academy of Sciences of the United States of America 106 (24): 9715-20. 16 June 2009

2008

A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation.
Seymour, P.A., Freude, K.K., Dubois, C.L., Shih, H.P., Patel, N.A. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Developmental Biology 323 (1): 19-30. 1 November 2008

Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation.
Jonckheere, N., Mayes, E., Shih, H.P., Li, B., Lioubinski, O., Dai, X. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Developmental Biology 318 (2): 224-35. 15 June 2008

2007

Immunohistochemical detection of beta-galactosidase or green fluorescent protein on tissue sections.
Seymour, P.A. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Methods in Molecular Biology 411 : 13-23. 13 September 2007

The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells.
Nelson, S.B., Schaffer, A.E. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Development 134 (13): 2491-500. July 2007

SOX9 is required for maintenance of the pancreatic progenitor cell pool.
Seymour, P.A., Freude, K.K., Tran, M.N., Mayes, E.E., Jensen, J., Kist, R., Scherer, G. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Proceedings of the National Academy of Sciences of the United States of America 104 (6): 1865-70. 6 February 2007

2005

Endodermal expression of Nkx6 genes depends differentially on Pdx1.
Pedersen, J.K., Nelson, S.B., Jorgensen, M.C., Henseleit, K.D., Fujitani, Y., Wright, C.V.E., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Serup, P.
Developmental Biology 288 (2): 487-501. 15 December 2005

NKX6 transcription factor activity is required for (α)- and (β)-cell development in the pancreas.
Henseleit, K.D., Nelson, S.B., Kuhlbrodt, K., Hennings, J.C., Ericson, J. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Development 132 (13): 3139-49. July 2005

Expression of Nkx6 genes in the hindbrain and gut of the developing mouse.
Nelson, S.B., Janiesch, C. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Journal of Histochemistry and Cytochemistry 53 (6): 787-90. June 2005

Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling.
Cai, J., Qi, Y., Hu, X., Tan, M., Liu, Z., Zhang, J., Li, Q., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Qiu, M.
Neuron 45 (1): 41-53. 6 January 2005

2004

Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice.
Mellitzer, G., Martín, M., Sidhoum-Jenny, M., Orvain, C., Barths, J., Seymour, P.A., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Gradwohl, G.
Molecular Endocrinology 18 (11): 2765-76. 1 November 2004

The MafA transcription factor appears to be responsible for tissue-specific expression of insulin.
Matsuoka, T., Artner, I., Henderson, E., Means, A., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Stein, R.
Proceedings of the National Academy of Sciences of the United States of America 101 (9): 2930-3. 2 March 2004

2003

Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons.
Müller, M., Jabs, N., Lorke, D.E., Fritzsch, B. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Development 130 (23): 5815-26. December 2003

Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor.
Liu, R., Cai, J., Hu, X., Tan, M., Qi, Y., German, M., Rubenstein, J., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Qiu, M.
Development 130 (25): 6221-31. December 2003

Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain.
Pattyn, A., Vallstedt, A., Dias, J.M., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Ericson, J.
Development 130 (17): 4149-59. September 2003

Expression of Sox transcription factors in the developing mouse pancreas.
Lioubinski, O., Müller, M., Wegner, M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Developmental Dynamics 227 (3): 402-8. July 2003

2001

Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification.
Vallstedt, A., Muhr, J., Pattyn, A., Pierani, A., Mendelsohn, M., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Jessell, T.M. and Ericson, J.
Neuron 31 (5): 743-55. 13 September 2001

2000

Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.
Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Sussel, L., Conners, J., Scheel, D., Kalamaras, J., Dela Cruz, F., Schwitzgebel, V., Hayes-Jordan, A. and German, M.
Development 127 (24): 5533-40. December 2000

Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates.
Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Paydar, S., Ericson, J., Briscoe, J., Berber, E., German, M., Jessell, T.M. and Rubenstein, J.L.
Genes and Development 14 (17): 2134-9. 1 September 2000

1998

A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets.
Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Griffen, S.C., Huang, J. and German, M.S.
Proceedings of the National Academy of Sciences of the United States of America 95 (20): 11572-7. 29 September 1998

1997

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development.
Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Neubüser, A., Kalamaras, J., Ee, H.C., Martin, G.R. and German, M.S.
Genes and Development 11 (13): 1662-73. 1 July 1997

The beta cell transcription factors and development of the pancreas.
Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and German, M.S.
Journal of Molecular Medicine 75 (5): 327-40. April 1997

1995

Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27.
Djavidani, B., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Kreutz, R., Zeh, K., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Mellon, S.H., Vecsei, P., Peters, J. and Ganten, D.
Journal of Hypertension 13 (6): 637-645. 1 January 1995

Rodent models for studying steroids and hypertension : from fetal development to cells in culture.
Mellon, S.H., Compagnone, N., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Cover, C., Ganten, D. and Djavidani, B.
Steroids 60 (1): 59-64. 1 January 1995

1994

Role of adrenal renin in the regulation of adrenal steroidogenesis corticotropin.
Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Ganten, D. and Mellon, S.H.
Proceedings of the National Academy of Sciences of the United States of America 91 (1): 148-152. 4 January 1994

1993

Regulation adrenaler Aldosteronsekretion und adrenalen Renins in TGR(mREN2)27.
Peters, J., Djavidani, B., Sander, M., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164 and Ganten, D.
Nieren- und Hochdruckkrankheiten 22 (7): 364-368. 1 January 1993

Renin gene expression and hypertension in transgenic animals.
Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Lee, M.A., Zhao, Y., Boehm, M., Bachmann, J., Sander, M., Djavidani, B., Bachmann, S., Zimmermann, F., Wilbertz, J., Zeh, K., Wagner, J., Peters, J. and Ganten, D.
In: Cellular and Molecular Biology of the Renin-Angiotensin System. CRC Press, Boca Raton, 60-93. 1 January 1993

1992

The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27.
Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Djavidani, B., Masergluth, C., Vecsei, P., Mullins, J.J., Ganten, D. and Peters, J.
Endocrinology 131 (2): 807-814. 1 August 1992

Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats.
Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Zhao, Y., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Lee, M.A., Bachmann, J., Boehm, M., Djavidani, B., Peters, J., Mullins, J.J. and Ganten, D.
Hypertension 19 (6 Pt 2): 681-686. 1 June 1992

Gesteigerte Aldosteronbiosynthese in TGR(mREN2)27: Funktionelle Bedeutung eines lokalen intraadrenalen Renin-Angiotensin-Systems.
Peters, J., Djavidani, B., Muenter, K., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Sander, M., Mullins, J.J. and Ganten, D.
Nieren- und Hochdruckkrankheiten 21 (11): 545-546. 1 January 1992

The role of adrenal renin in steroid metabolism and development of hypertension in transgenic rats TGR(Messenger REN2).
Peters, J., Sander, M., Munter, K., Lee, M.A., Djavidani, B., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Maser-Gluth, C., Vecsei, P., Ganten, D. and Mullins, J.J.
In: Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats (Colloque Inserm ; 218). John Libbey Eurotext, Paris, 345-347. 1 January 1992