Browse by Research Team

2023

Editorial: Modulation of human immune parameters by anticancer therapies, volume II.
Na, I.K. and Sack, U. and Sánchez-Ramón, S.
Frontiers in Immunology 14 : 1249099. 26 July 2023

Consensus molecular subtypes as biomarkers of fluorouracil and folinic acid maintenance therapy with or without panitumumab in (RAS) wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212).
Stahler, A. and Hoppe, B. and Na, I.K. and Keilholz, L. and Müller, L. and Karthaus, M. and Fruehauf, S. and Graeven, U. and Fischer von Weikersthal, L. and Goekkurt, E. and Kasper, S. and Kind, A.J. and Kurreck, A. and Alig, A.H.S. and Held, S. and Reinacher-Schick, A. and Heinemann, V. and Horst, D. and Jarosch, A. and Stintzing, S. and Trarbach, T. and Modest, D.P.
Journal of Clinical Oncology 41 (16): 2975-2987. 1 June 2023

Single-cell clonal tracking of persistent T-cells in allogeneic hematopoietic stem cell transplantation.
Obermayer, B. and Keilholz, L. and Conrad, T. and Frentsch, M. and Blau, I.W. and Vuong, L. and Lesch, S. and Movasshagi, K. and Tietze-Stolley, C. and Loyal, L. and Henze, L. and Penack, O. and Stervbo, U. and Babel, N. and Haas, S. and Beule, D. and Bullinger, L. and Wittenbecher, Friedrich and Na, I.K.
Frontiers in Immunology 14 : 1114368. 10 February 2023

2022

Long-term observation of the frequency of secondary colorectal cancer and other malignancies in tyrosine kinase inhibitor treated chronic myeloid leukemia patients and controls.
Winkelmann, N. and Schwarz, M. and Hildebrandt, B. and Henke, O. and Bullinger, L. and Na, I.K. and Stintzing, S. and le Coutre, P.
eJHaem: The Official Journal of the British Society for Haematology 3 (3): 949-953. August 2022

Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma.
Schmiester, M. and Maier, R. and Riedel, R. and Durek, P. and Frentsch, M. and Kolling, S. and Mashreghi, M.F. and Jenq, R. and Zhang, L. and Peterson, C.B. and Bullinger, L. and Chang, H.D. and Na, I.K.
Gut Microbes 14 (1): e2081475. 29 May 2022

Paired donor and recipient immunophenotyping in allogeneic hematopoietic stem cell transplantation: a cellular network approach.
Wittenbecher, F. and Lesch, S. and Kolling, S. and Blau, I.W. and Vuong, L. and Borchert, F. and Movasshagi, K. and Tietze-Bürger, C. and Penack, O. and Ahn, J. and Bullinger, L. and Frentsch, M. and Na, I.K.
Frontiers in Immunology 13 : 874499. 23 May 2022

Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade.
Kofla, G. and Radecke, C. and Frentsch, M. and Walther, W. and Stintzing, S. and Riess, H. and Bullinger, L. and Na, I.K.
OncoImmunology 11 (1): 2068109. 25 April 2022

Simultaneous genetic ablation of PD-1, LAG-3, and TIM-3 in CD8 T cells delays tumor growth and improves survival outcome.
Ciraolo, E. and Althoff, S. and Ruß, J. and Rosnev, S. and Butze, M. and Pühl, M. and Frentsch, M. and Bullinger, L. and Na, I.K.
International Journal of Molecular Sciences 23 (6): 3207. 16 March 2022

Acute left ventricular insufficiency in a Burkitt Lymphoma patient with myocardial involvement and extensive local tumor cell lysis: a case report.
Schmiester, M. and Tranter, E. and Lorusso, A. and Blaschke, F. and Geisel, D. and Bullinger, L. and Damm, F. and Na, I.K.
BMC Cardiovascular Disorders 22 (1): 31. 4 February 2022

Treatment with ribociclib shows favourable immunomodulatory effects in patients with hormone receptor-positive breast cancer-findings from the RIBECCA trial.
Peuker, C.A. and Yaghobramzi, S. and Grunert, C. and Keilholz, L and Gjerga, E. and Hennig, S. and Schaper, S. and Na, I.K. and Keller, U. and Brucker, S. and Decker, T. and Fasching, P. and Fehm, T. and Janni, W. and Kümmel, S. and Schneeweiss, A. and Schuler, M. and Lüftner, D. and Busse, A.
European Journal of Cancer 162 : 45-55. February 2022

Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S. and Bittner, A. and Frick, M. and Kase, J. and Hoffmann, J. and Trenker, C. and Keller, U. and Bogner, C. and Hüttmann, A. and Dürig, J. and Janz, M. and Mathas, S. and Marks, R. and Krohn, U. and Na, I.K. and Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 63 (1): 84-92. January 2022

2021

CD4+ T cell dependent B cell recovery and function after autologous hematopoietic stem cell transplantation.
Heck, C. and Steiner, S. and Kaebisch, E.M. and Frentsch, M. and Wittenbecher, F. and Scheibenbogen, C. and Hanitsch, L.G. and Nogai, A. and le Coutre, P. and Bullinger, L. and Blau, I.W. and Na, I.K.
Frontiers in Immunology 12 : 736137. September 2021

Cerebral EBV-positive PTLD controlled by PD-1 checkpoint blockade in a liver transplant patient.
Bittner, A. and Radke, J. and Eurich, D. and Wiener, E. and Denker, S. and Anagnostopoulos, I. and Na, I.K. and Heppner, F.L. and Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 62 (8): 2026-2029. August 2021

Long-term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges.
Herda, S. and Heimann, A. and Obermayer, B. and Ciraolo, E. and Althoff, S. and Ruß, J. and Grunert, C. and Busse, A. and Bullinger, L. and Pezzutto, A. and Blankenstein, T. and Beule, D. and Na, I.K.
International Journal of Cancer 148 (12): 3097-3110. 15 June 2021

CD40 activity on mesenchymal cells negatively regulates OX40L to maintain bone marrow immune homeostasis under stress conditions.
Bassani, B. and Tripodo, C. and Portararo, P. and Gulino, A. and Botti, L. and Chiodoni, C. and Jachetti, E. and Bolli, N. and Ciciarello, M. and Joehrens, K. and Anagnostopoulos, I. and Na, I.K. and Curti, A. and Colombo, M.P. and Sangaletti, S.
Frontiers in Immunology 12 : 662048. 18 May 2021

2020

Spatio-temporal bone remodeling after hematopoietic stem cell transplantation.
Schwarz, C.S. and Bucher, C.H. and Schlundt, C. and Mertlitz, S. and Riesner, K. and Kalupa, M. and Verlaat, L. and Schmidt-Bleek, O. and Sass, R.A. and Schmidt-Bleek, K. and Duda, G.N. and Penack, O. and Na, I.K.
International Journal of Molecular Sciences 22 (1): 267. 29 December 2020

HCoV- and SARS-CoV-2 cross-reactive T cells in CVID patients.
Steiner, S. and Sotzny, F. and Bauer, S. and Na, I.K. and Schmueck-Henneresse, M. and Corman, V.M. and Schwarz, T. and Drosten, C. and Wendering, D.J. and Behrends, U. and Volk, H.D. and Scheibenbogen, C. and Hanitsch, L.G.
Frontiers in Immunology 11 : 607918. 23 December 2020

Editorial: Modulation of human immune parameters by anticancer therapies.
Sack, U. and Tarnok, A. and Preijers, F. and Köhl, U. and Na, I.K.
Frontiers in Immunology 11 : 621556. 2 December 2020

CD40 provides immune privilege to the bone marrow hematopoietic niche.
Bassani, B. and Gulino, A. and Portararo, P. and Botti, L. and Cappetti, B. and Chiodoni, C. and Bolli, N. and Ciciarello, M. and Joehrens, K. and Anagnostopoulos, I. and Na, I.K. and Curti, A. and Tripodo, C. and Colombo, M.P. and Sangaletti, S.
bioRxiv : 2020.08.10.243691. 10 August 2020

2019

A Phase I/II first-line study of R-CHOP plus B-cell receptor/NF-κB-double-targeting to molecularly assess therapy response.
Denker, S. and Bittner, A. and Na, I.K. and Kase, J. and Frick, M. and Anagnostopoulos, I. and Hummel, M. and Schmitt, C.A.
International Journal of Hematologic Oncology 8 (4): IJH20. 19 December 2019

Cytotoxic effects of rabbit anti-thymocyte globulin preparations on primary human thymic epithelial cells.
Kaebisch, E.M. and Cho, M.Y. and Oh, Y.S. and Olfe, L.I. and Szyska, M. and Becker, S.C. and Reinke, P. and Volk, H.D. and Gillissen, B. and Bullinger, L. and Thiel, A. and Na, I.K.
Transplantation 103 (11): 2234-2244. November 2019

Chaperone protein HSC70 regulates intercellular transfer of Y chromosome antigen DBY.
Kretschmann, S. and Herda, S. and Bruns, H. and Russ, J. and van der Meijden, E.D. and Schlötzer-Schrehardt, U. and Griffioen, M. and Na, I.K. and Mackensen, A. and Kremer, A.N.
Journal of Clinical Investigation 129 (7): 2952-2963. 1 July 2019

Current clinical practice and challenges in the management of secondary immunodeficiency in hematological malignancies.
Na, I.K. and Buckland, M. and Agostini, C. and Edgar, J.D.M. and Friman, V. and Michallet, M. and Sánchez-Ramón, S. and Scheibenbogen, C. and Quinti, I.
European Journal of Haematology 102 (6): 447-456. June 2019

2018

Nrf2 regulates CD4(+) T cell-induced acute graft-versus-host disease in mice.
Tsai, J.J. and Velardi, E. and Shono, Y. and Argyropoulos, K.V. and Holland, A.M. and Smith, O.M. and Yim, N.L. and Rao, U.K. and Kreines, F.M. and Lieberman, S.R. and Young, L.F. and Lazrak, A. and Youssef, S. and Fu, Y.Y. and Liu, C. and Lezcano, C. and Murphy, G.F. and Na, I.K. and Jenq, R.R. and Hanash, A.M. and Dudakov, J.A. and van den Brink, M.R.M.
Blood 132 (26): 2763-2774. 27 December 2018

A comparative analysis of human bone marrow-resident and peripheral memory B cells.
Becker, S.C. and Szyska, M. and Mensen, A. and Hellwig, K. and Otto, R. and Olfe, L. and Volk, H.D. and Dörner, T. and Dörken, B. and Scheibenbogen, C. and Schröder, J. and Hocke, A.C. and Na, I.K.
Journal of Allergy and Clinical Immunology 141 (5): 1911-1913. May 2018

Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells.
Hammer, Q. and Rückert, T. and Borst, E.M. and Dunst, J. and Haubner, A. and Durek, P. and Heinrich, F. and Gasparoni, G. and Babic, M. and Tomic, A. and Pietra, G. and Nienen, M. and Blau, I.W. and Hofmann, J. and Na, I.K. and Prinz, I. and Koenecke, C. and Hemmati, P. and Babel, N. and Arnold, R. and Walter, J. and Thurley, K. and Mashreghi, M.F. and Messerle, M. and Romagnani, C.
Nature Immunology 19 (5): 453-463. May 2018

A transgenic dual-luciferase reporter mouse for longitudinal and functional monitoring of T cells in vivo.
Szyska, M. and Herda, S. and Althoff, S. and Heimann, A. and Russ, J. and D'Abundo, D. and Dang, T.M. and Durieux, I. and Dörken, B. and Blankenstein, T. and Na, I.K.
Cancer Immunology Research 6 (1): 110-120. January 2018

2017

Predictive significance of the European LeukemiaNet classification of genetic aberrations in patients with acute myeloid leukemia undergoing allogeneic stem cell transplantation.
Hemmati, P.G. and Vuong, L.G. and Terwey, T.H. and Jehn, C.F. and Le Coutre, P. and Penack, O. and Na, I.K. and Dörken, B. and Arnold, R.
European Journal of Haematology 98 (2): 160-168. February 2017

2016

Bone marrow GvHD after allogeneic hematopoietic stem cell transplantation.
Szyska, M. and Na, I.K.
Frontiers in Immunology 7 : 118. 30 March 2016

2015

Allogeneic stem cell transplantation for refractory acute myeloid leukemia: a single center analysis of long-term outcome.
Hemmati, P.G. and Terwey, T.H. and Na, I.K. and Jehn, C.F. and le Coutre, P. and Vuong, L.G. and Doerken, B. and Arnold, R.
European Journal of Haematology 95 (6): 498-506. December 2015

Altered B-cell subsets and functional B-cell defects in selective IgM deficiency.
Mensen, A. and Krause, T. and Hanitsch, L.G. and Meisel, C. and Kleint, M.E. and Volk, H.D. and Na, I.K. and Scheibenbogen, C.
Clinical Immunology 161 (2): 96-102. December 2015

Apoptosis-susceptibility prolongs the lack of memory B cells in acute leukemic patients after allogeneic hematopoietic stem cell transplantation.
Mensen, A. and Oh, Y. and Becker, S.C. and Hemmati, P.G. and Jehn, C. and Westermann, J. and Szyska, M. and Göldner, H. and Dörken, B. and Scheibenbogen, C. and Arnold, R. and Na, I.K.
Biology of Blood and Marrow Transplantation 21 (11): 1895-1906. November 2015

Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multi-center survey.
Zeiser, R. and Burchert, A. and Lengerke, C. and Verbeek, M. and Maas-Bauer, K. and Metzelder, S.K. and Spoerl, S. and Ditschkowski, M. and Ecsedi, M. and Sockel, K. and Ayuk, F. and Ajib, S. and de Fontbrune, F.S. and Na, I.K. and Penter, L. and Holtick, U. and Wolf, D. and Schuler, E. and Meyer, E. and Apostolova, P. and Bertz, H. and Marks, R. and Lübbert, M. and Wäsch, R. and Scheid, C. and Stölzel, F. and Ordemann, R. and Bug, G. and Kobbe, G. and Negrin, R. and Brune, M. and Spyridonidis, A. and Schmitt-Gräff, A. and van der Velden, W. and Huls, G. and Mielke, S. and Grigoleit, G.U. and Kuball, J. and Flynn, R. and Ihorst, G. and Du, J. and Blazar, B.R. and Arnold, R. and Kröger, N. and Passweg, J. and Halter, J. and Socie, G. and Beelen, D. and Peschel, C. and Neubauer, A. and Finke, J. and Duyster, J. and von Bubnoff, N.
Leukemia 29 (10): 2062-2068. October 2015

Emerging role of tyrosine kinases as drugable targets in cancer.
Na, I.K. and Le Coutre, P.
Biomarker Insights 10 (S3): 29-31. 10 September 2015

Impact of early remission by induction therapy on allogeneic stem cell transplantation for acute myeloid leukemia with an intermediate risk karyotype in first complete remission.
Hemmati, P.G. and Terwey, T.H. and Na, I.K. and le Coutre, P. and Jehn, C.F. and Vuong, L.G. and Dörken, B. and Arnold, R.
European Journal of Haematology 94 (5): 431-438. May 2015

2014

Comparison of different rabbit ATG preparation effects on early lymphocyte subset recovery after allogeneic HSCT and its association with EBV-mediated PTLD.
Mensen, A. and Na, I.K. and Häfer, R. and Meerbach, A. and Schlecht, M. and Pietschmann, M.L. and Gruhn, B.
Journal of Cancer Research and Clinical Oncology 140 (11): 1971-1980. November 2014

Bone marrow T-cell infiltration during acute GVHD is associated with delayed B-cell recovery and function after HSCT.
Mensen, A. and Jöhrens, K. and Anagnostopoulos, I. and Demski, S. and Oey, M. and Stroux, A. and Hemmati, P. and Westermann, J. and Blau, O. and Wittenbecher, F. and Movassaghi, K. and Szyska, M. and Thomas, S. and Dörken, B. and Scheibenbogen, C. and Arnold, R. and Na, I.K.
Blood 124 (6): 963-972. 7 August 2014

2013

Rabbit antithymocyte globulin induces rapid expansion of effector memory CD8 T cells without accelerating acute graft versus host disease.
Wittenbecher, F. and Rieger, K. and Dziubianau, M. and Herholz, A. and Mensen, A. and Blau, I.W. and Uharek, L. and Dörken, B. and Thiel, A. and Na, I.K.
Leukemia Research Reports 2 (2): 82-85. 27 September 2013

Utilization of TREC and KREC quantification for the monitoring of early T- and B-cell neogenesis in adult patients after allogeneic hematopoietic stem cell transplantation.
Mensen, A. and Ochs, C. and Stroux, A. and Wittenbecher, F. and Szyska, M. and Imberti, L. and Fillatreau, S. and Uharek, L. and Arnold, R. and Dörken, B. and Thiel, A. and Scheibenbogen, C. and Na, I.K.
Journal of Translational Medicine 11 (1): 188. 14 August 2013

PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating graft-versus-host-disease.
Ghosh, A. and Holland, A.M. and Dogan, Y. and Yim, N. and Rao, U.K. and Young, L.F. and West, M.L. and Singer, N.V. and Lee, H. and Na, I.K. and Tsai, J.J. and Jenq, R. and Penack, O. and Hanash, A.M. and Lezcano, C. and Murphy, G.F. and Liu, C. and Sadelain, M. and Sauer, M.G. and Sant'Angelo, D. and van den Brink, M.R.M.
Cancer Research 73 (15): 4687-4696. 1 August 2013

Rabbit antithymocyte globulin (Thymoglobulin(R)) impairs the thymic output of both conventional and regulatory CD4(+) T cells after allogeneic hematopoietic stem cell transplantation in adult patients.
Na, I.K. and Wittenbecher, F. and Dziubianau, M. and Herholz, A. and Mensen, A. and Kunkel, D. and Blau, O. and Blau, I. and Thiel, E. and Uharek, L. and Scheibenbogen, C. and Rieger, K. and Thiel, A.
Haematologica 98 (1): 23-30. January 2013

2011

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL.
Hanash, A.M. and Kappel, L.W. and Yim, N.L. and Nejat, R.A. and Goldberg, G.L. and Smith, O.M. and Rao, U.K. and Dykstra, L. and Na, I.K. and Holland, A.M. and Dudakov, J.A. and Liu, C. and Murphy, G.F. and Leonard, W.J. and Heller, G. and van den Brink, M.R.M.
Blood 118 (2): 446-455. 14 July 2011

Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation.
Lu, S.X. and Kappel, L.W. and Charbonneau-Allard, A.M. and Atallah, R. and Holland, A.M. and Turbide, C. and Hubbard, V.M. and Rotolo, J.A. and Smith, M. and Suh, D. and King, C. and Rao, U.K. and Yim, N. and Bautista, J.L. and Jenq, R.R. and Penack, O. and Na, I.K. and Liu, C. and Murphy, G. and Alpdogan, O. and Blumberg, R.S. and Macian, F. and Holmes, K.V. and Beauchemin, N. and van den Brink, M.R.M.
PLoS ONE 6 (7): e21611. 6 July 2011

2010

Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo.
Na, I.K. and Markley, J.C. and Tsai, J.J. and Yim, N.L. and Beattie, B.J. and Klose, A.D. and Holland, A.M. and Ghosh, A. and Rao, U.K. and Stephan, M.T. and Serganova, I. and Santos, E.B. and Brentjens, R.J. and Blasberg, R.G. and Sadelain, M. and van den Brink, M.R.M.
Blood 116 (11): e18-e25. 16 September 2010

Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease.
Lu, S.X. and Holland, A.M. and Na, I.K. and Terwey, T.H. and Alpdogan, O. and Bautista, J.L. and Smith, O.M. and Suh, D. and King, C. and Kochman, A. and Hubbard, V.M. and Rao, U.K. and Yim, N. and Liu, C. and Laga, A.C. and Murphy, G. and Jenq, R.R. and Zakrzewski, J.L. and Penack, O. and Dykstra, L. and Bampoe, K. and Perez, L. and Furie, B. and Furie, B. and van den Brink, M.R.M.
Journal of Immunology 185 (3): 1912-1919. 1 August 2010

Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth.
Penack, O. and Henke, E. and Suh, D. and King, C.G. and Smith, O.M. and Na, I.K. and Holland, A.M. and Ghosh, A. and Lu, S.X. and Jenq, R.R. and Liu, C. and Murphy, G.F. and Lu, T.T. and May, C. and Scheinberg, D.A. and Gao, D.C. and Mittal, V. and Heller, G. and Benezra, R. and van den Brink, M.R.M.
Journal of the National Cancer Institute 102 (12): 894-908. 16 June 2010

Human peripheral blood and bone marrow Epstein-Barr virus-specific T-cell repertoire in latent infection reveals distinct memory T-cell subsets.
Guerreiro, M. and Na, I.K. and Letsch, A. and Haase, D. and Bauer, S. and Meisel, C. and Roemhild, A. and Reinke, P. and Volk, H.D. and Scheibenbogen, C.
European Journal of Immunology 40 (6): 1566-1576. June 2010

The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease.
Na, I.K. and Lu, S.X. and Yim, N.L. and Goldberg, G.L. and Tsai, J. and Rao, U. and Smith, O.M. and King, C.G. and Suh, D. and Hirschhorn-Cymerman, D. and Palomba, L. and Penack, O. and Holland, A.M. and Jenq, R.R. and Ghosh, A. and Tran, H. and Merghoub, T. and Liu, C. and Sempowski, G.D. and Ventevogel, M. and Beauchemin, N. and van den Brink, M.R.M.
Journal of Clinical Investigation 120 (1): 343-356. January 2010

2009

Human bone marrow as a source to generate CMV-specific CD4+ T cells with multifunctional capacity.
Na, I.K. and Letsch, A. and Guerreiro, M. and Bauer, S. and Noack, I. and Geginat, J. and Reinke, P. and Loesch, M. and Kienapfel, H. and Thiel, E. and Volk, H.D. and Scheibenbogen, C.
Journal of Immunotherapy 32 (9): 907-913. November 2009

NOD2 regulates hematopoietic cell function during graft-versus-host disease.
Penack, O. and Smith, O.M. and Cunningham-Bussel, A. and Liu, X. and Rao, U. and Yim, N. and Na, I.K. and Holland, A.M. and Ghosh, A. and Lu, S.X. and Jenq, R.R. and Liu, C. and Murphy, G.F. and Brandl, K. and van den Brink, M.R.M.
Journal of Experimental Medicine 206 (10): 2101-2110. 28 September 2009

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation.
Jenq, R.R. and King, C.G. and Volk, C. and Suh, D. and Smith, O.M. and Rao, U.K. and Yim, N.L. and Holland, A.M. and Lu, S.X. and Zakrzewski, J.L. and Goldberg, G.L. and Diab, A. and Alpdogan, O. and Penack, O. and Na, I.K. and Kappel, L.W. and Wolchok, J.D. and Houghton, A.N. and Perales, M.A. and van den Brink, M.R.M.
Blood 113 (7): 1574-1580. 12 February 2009

2008

Nuclear expression of CXCR4 in tumor cells of non-small cell lung cancer is correlated with lymph node metastasis.
Na, I.K. and Scheibenbogen, C. and Adam, C. and Stroux, A. and Ghadjar, P. and Thiel, E. and Keilholz, U. and Coupland, S.E.
Human Pathology 39 (12): 1751-1755. December 2008

Identification of truncated chemokine receptor 7 in human colorectal cancer unable to localize to the cell surface and unreactive to external ligands.
Na, I.K. and Busse, A. and Scheibenbogen, C. and Ghadjar, P. and Coupland, S.E. and Letsch, A. and Loddenkemper, C. and Stroux, A. and Bauer, S. and Thiel, E. and Keilholz, U.
International Journal of Cancer 123 (7): 1565-1572. 1 October 2008

Sensitivity of tumor cells to proteasome inhibitors is associated with expression levels and composition of proteasome subunits.
Busse, A. and Kraus, M. and Na, I.K. and Rietz, A. and Scheibenbogen, C. and Driessen, C. and Blau, I.W. and Thiel, E. and Keilholz, U.
Cancer 112 (3): 659-670. 1 February 2008

2007

CMV-specific central memory T cells reside in bone marrow.
Letsch, A. and Knoedler, M. and Na, I.K. and Kern, F. and Asemissen, A.M. and Keilholz, U. and Loesch, M. and Thiel, E. and Volk, H.D. and Scheibenbogen, C.
European Journal of Immunology 37 (11): 3063-3068. November 2007

Addition of GM-CSF to a peptide/KLH vaccine results in increased frequencies of CXCR3-expressing KLH-specific T cells.
Na, I.K. and Keilholz, U. and Letsch, A. and Bauer, S. and Asemissen, A.M. and Nagorsen, D. and Thiel, E. and Scheibenbogen, C.
Cancer Immunology Immunotherapy 56 (3): 391-396. March 2007

2006

Developmental stage-specific shift in responsiveness to chemokines during human B-cell development.
Honczarenko, M. and Glodek, A.M. and Swierkowski, M. and Na, I.K. and Silberstein, L.E.
Experimental Hematology 34 (8): 1093-1100. August 2006

Chemokine receptor CCR6 expression level and liver metastases in colorectal cancer.
Ghadjar, P. and Coupland, S.E. and Na, I.K. and Noutsias, M. and Letsch, A. and Stroux, A. and Bauer, S. and Buhr, H.J. and Thiel, E. and Scheibenbogen, C. and Keilholz, U.
Journal of Clinical Oncology 24 (12): 1910-1916. 20 April 2006

Lymphomas are sensitive to perforin-dependent cytotoxic pathways despite expression of PI-9 and overexpression of bcl-2.
Godal, R. and Keilholz, U. and Uharek, L. and Letsch, A. and Asemissen, A.M. and Busse, A. and Na, I.K. and Thiel, E. and Scheibenbogen, C.
Blood 107 (8): 3205-3211. 15 April 2006

2005

Expression of the chemokine receptors CXCR4, CXCR5, and CCR7 in primary central nervous system lymphoma.
Jahnke, K. and Coupland, S.E. and Na, I.K. and Loddenkemper, C. and Keilholz, U. and Korfel, A. and Stein, H. and Thiel, E. and Scheibenbogen, C.
Blood 106 (1): 384-385. 1 July 2005

Imatinib mesylate radiosensitizes human glioblastoma cells through inhibition of platelet-derived growth factor receptor.
Holdhoff, M. and Kreuzer, K.A. and Appelt, C. and Scholz, R. and Na, I.K. and Hildebrandt, B. and Riess, H. and Jordan, A. and Schmidt, C.A. and Van Etten, R.A. and Doerken, B. and LeCoutre, P.
Blood Cells Molecules and Diseases 34 (2): 181-185. 1 March 2005

Quantitative RT-PCR of Wilms tumor gene transcripts (WT1) for the molecular monitoring of patients with accelerated phase bcr/abl + CML.
Na, I.K. and Kreuzer, K.A. and Lupberger, J. and Doerken, B. and Coutre, P.
Leukemia Research Reports 29 (3): 343-345. 1 March 2005

2003

Imatinib in Philadelphia chromosome-positive chronic phase CML patients: molecular and cytogenetic response rates and prediction of clinical outcome.
Le Coutre, P. and Kreuzer, K.A. and Na, I.K. and Schwarz, M. and Lupberger, J. and Holdhoff, M. and Baskaynak, G. and Gschaidmeier, H. and Platzbecker, U. and Ehninger, G. and Prejzner, W. and Huhn, D. and Schmidt, C.A.
American Journal of Hematology 73 (4): 249-255. August 2003

Preexistence and evolution of imatinib mesylate-resistant clones in chronic myelogenous leukemia detected by a PNA-based PCR clamping technique.
Kreuzer, K.A. and Le Coutre, P. and Landt, O. and Na, I.K. and Schwarz, M. and Schultheis, K. and Hochhaus, A. and Doerken, B.
Annals of Hematology 82 (5): 284-289. May 2003

2002

Determination of alpha-1 acid glycoprotein in patients with Ph+ chronic myeloid leukemia during the first 13 weeks of therapy with STI571.
le Coutre, P. and Kreuzer, K.A. and Na, I.K. and Lupberger, J. and Holdhoff, M. and Appelt, C. and Schwarz, M. and Mueller, C. and Gambacorti-Passerini, C. and Platzbecker, U. and Bonnet, R. and Ehninger, G. and Schmidt, C.A.
Blood Cells Molecules and Diseases 28 (1): 75-85. January 2002

2001

Fluorescent 5'-exonuclease assay for the absolute quantification of Wilms' tumour gene (WT1) mRNA: implications for monitoring human leukaemias.
Kreuzer, K.A. and Saborowski, A. and Lupberger, J. and Appelt, C. and Na, I.K. and le Coutre, P. and Schmidt, C.A.
British Journal of Haematology 114 (2): 313-318. August 2001