Browse by Research Team

2024

Comparison of R-CHOP-14 and R-mini-CHOP in older adults with diffuse large B-cell lymphoma - a retrospective multicenter cohort study.
Dilbaz, Z.G., Denker, S., Ankermann, C., Bittenbring, J.T., Kaddu-Mulindwa, D., Kunte, A.S., Hünecke, S., Poeschel, V., Stilgenbauer, S., Thurner, L., Na, I.K., Bewarder, M. and Christofyllakis, K.
European Journal of Haematology 113 (5): 675-684. November 2024

Comparable CD8(+) T-cell responses to SARS-CoV-2 vaccination in single-cell transcriptomics of recently allogeneic transplanted patients and healthy individuals.
Tranter, Eva, Frentsch, Marco, Hütter-Krönke, Marie Luise, Vuong, Giang Lam, Busch, David, Loyal, Lucie, Henze, Larissa, Rosnev, Stanislav, Blau, Igor-Wolfgang, Thiel, Andreas, Beule, D., Bullinger, L., Obermayer, B. and Na, I.K.
Journal of Medical Virology 96 (3): e29539. March 2024

2023

Clinical implications and dynamics of clonal hematopoiesis in anti-CD19 CAR T-cell treated patients.
Panagiota, V., Kerschbaum, J.F., Penack, O., Stein, C.M., Arends, C.M., Koenecke, C., Strzelecka, P.M., Kloos, A., Wiegand, L., Lasch, A., Altwasser, R., Halik, A., Gabdoulline, R., Thomson, J., Weibl, K., Franke, G.N., Berger, C., Hasenkamp, J., Ayuk, F., Na, I.K., Beutel, G., Keller, U., Bullinger, L., Wulf, G.G., Kröger, N., Vucinic, V., Heuser, M. and Damm, F.
HemaSphere 7 (10): e957. October 2023

Editorial: Modulation of human immune parameters by anticancer therapies, volume II.
Na, I.K., Sack, U. and Sánchez-Ramón, S.
Frontiers in Immunology 14 : 1249099. 26 July 2023

Consensus molecular subtypes as biomarkers of fluorouracil and folinic acid maintenance therapy with or without panitumumab in (RAS) wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212).
Stahler, A., Hoppe, B., Na, I.K., Keilholz, L., Müller, L., Karthaus, M., Fruehauf, S., Graeven, U., Fischer von Weikersthal, L., Goekkurt, E., Kasper, S., Kind, A.J., Kurreck, A., Alig, A.H.S., Held, S., Reinacher-Schick, A., Heinemann, V., Horst, D., Jarosch, A., Stintzing, S., Trarbach, T. and Modest, D.P.
Journal of Clinical Oncology 41 (16): 2975-2987. 1 June 2023

Single-cell clonal tracking of persistent T-cells in allogeneic hematopoietic stem cell transplantation.
Obermayer, B., Keilholz, L., Conrad, T., Frentsch, M., Blau, I.W., Vuong, L., Lesch, S., Movasshagi, K., Tietze-Stolley, C., Loyal, L., Henze, L., Penack, O., Stervbo, U., Babel, N., Haas, S., Beule, D., Bullinger, L., Wittenbecher, F. and Na, I.K.
Frontiers in Immunology 14 : 1114368. 10 February 2023

2022

Long-term observation of the frequency of secondary colorectal cancer and other malignancies in tyrosine kinase inhibitor treated chronic myeloid leukemia patients and controls.
Winkelmann, N., Schwarz, M., Hildebrandt, B., Henke, O., Bullinger, L., Na, I.K., Stintzing, S. and le Coutre, P.
eJHaem: The Official Journal of the British Society for Haematology 3 (3): 949-953. August 2022

Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma.
Schmiester, M., Maier, R., Riedel, R., Durek, P., Frentsch, M., Kolling, S., Mashreghi, M.F., Jenq, R., Zhang, L., Peterson, C.B., Bullinger, L., Chang, H.D. and Na, I.K.
Gut Microbes 14 (1): e2081475. 29 May 2022

Paired donor and recipient immunophenotyping in allogeneic hematopoietic stem cell transplantation: a cellular network approach.
Wittenbecher, F., Lesch, S., Kolling, S., Blau, I.W., Vuong, L., Borchert, F., Movasshagi, K., Tietze-Bürger, C., Penack, O., Ahn, J., Bullinger, L., Frentsch, M. and Na, I.K.
Frontiers in Immunology 13 : 874499. 23 May 2022

Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade.
Kofla, G., Radecke, C., Frentsch, M., Walther, W., Stintzing, S., Riess, H., Bullinger, L. and Na, I.K.
OncoImmunology 11 (1): 2068109. 25 April 2022

Simultaneous genetic ablation of PD-1, LAG-3, and TIM-3 in CD8 T cells delays tumor growth and improves survival outcome.
Ciraolo, E., Althoff, S., Ruß, J., Rosnev, S., Butze, M., Pühl, M., Frentsch, M., Bullinger, L. and Na, I.K.
International Journal of Molecular Sciences 23 (6): 3207. 16 March 2022

Acute left ventricular insufficiency in a Burkitt Lymphoma patient with myocardial involvement and extensive local tumor cell lysis: a case report.
Schmiester, M., Tranter, E., Lorusso, A., Blaschke, F., Geisel, D., Bullinger, L., Damm, F. and Na, I.K.
BMC Cardiovascular Disorders 22 (1): 31. 4 February 2022

Treatment with ribociclib shows favourable immunomodulatory effects in patients with hormone receptor-positive breast cancer-findings from the RIBECCA trial.
Peuker, C.A., Yaghobramzi, S., Grunert, C., Keilholz, L, Gjerga, E., Hennig, S., Schaper, S., Na, I.K., Keller, U., Brucker, S., Decker, T., Fasching, P., Fehm, T., Janni, W., Kümmel, S., Schneeweiss, A., Schuler, M., Lüftner, D. and Busse, A.
European Journal of Cancer 162 : 45-55. February 2022

Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S., Bittner, A., Frick, M., Kase, J., Hoffmann, J., Trenker, C., Keller, U., Bogner, C., Hüttmann, A., Dürig, J., Janz, M., Mathas, S., Marks, R., Krohn, U., Na, I.K., Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 63 (1): 84-92. January 2022

2021

CD4+ T cell dependent B cell recovery and function after autologous hematopoietic stem cell transplantation.
Heck, C., Steiner, S., Kaebisch, E.M., Frentsch, M., Wittenbecher, F., Scheibenbogen, C., Hanitsch, L.G., Nogai, A., le Coutre, P., Bullinger, L., Blau, I.W. and Na, I.K.
Frontiers in Immunology 12 : 736137. September 2021

Cerebral EBV-positive PTLD controlled by PD-1 checkpoint blockade in a liver transplant patient.
Bittner, A., Radke, J., Eurich, D., Wiener, E., Denker, S., Anagnostopoulos, I., Na, I.K., Heppner, F.L., Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 62 (8): 2026-2029. August 2021

Long-term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges.
Herda, S., Heimann, A., Obermayer, B., Ciraolo, E., Althoff, S., Ruß, J., Grunert, C., Busse, A., Bullinger, L., Pezzutto, A., Blankenstein, T., Beule, D. and Na, I.K.
International Journal of Cancer 148 (12): 3097-3110. 15 June 2021

CD40 activity on mesenchymal cells negatively regulates OX40L to maintain bone marrow immune homeostasis under stress conditions.
Bassani, B., Tripodo, C., Portararo, P., Gulino, A., Botti, L., Chiodoni, C., Jachetti, E., Bolli, N., Ciciarello, M., Joehrens, K., Anagnostopoulos, I., Na, I.K., Curti, A., Colombo, M.P. and Sangaletti, S.
Frontiers in Immunology 12 : 662048. 18 May 2021

Sekundäre Immundefekte bei hämatoonkologischen Erkrankungen.
Käbisch, E. and Na, I.K.
Tagliche Praxis 65 (1): 12-23. 2021

Sekundäre Immundefekte bei hämatoonkologischen Erkrankungen [Secondary immunodeficiency in hematological and oncological diseases].
Käbisch, E. and Na, I.K.
Internistische Praxis 63 (4): 570-581. 2021

2020

Spatio-temporal bone remodeling after hematopoietic stem cell transplantation.
Schwarz, C.S., Bucher, C.H., Schlundt, C., Mertlitz, S., Riesner, K., Kalupa, M., Verlaat, L., Schmidt-Bleek, O., Sass, R.A., Schmidt-Bleek, K., Duda, G.N., Penack, O. and Na, I.K.
International Journal of Molecular Sciences 22 (1): 267. 29 December 2020

HCoV- and SARS-CoV-2 cross-reactive T cells in CVID patients.
Steiner, S., Sotzny, F., Bauer, S., Na, I.K., Schmueck-Henneresse, M., Corman, V.M., Schwarz, T., Drosten, C., Wendering, D.J., Behrends, U., Volk, H.D., Scheibenbogen, C. and Hanitsch, L.G.
Frontiers in Immunology 11 : 607918. 23 December 2020

Editorial: Modulation of human immune parameters by anticancer therapies.
Sack, U., Tarnok, A., Preijers, F., Köhl, U. and Na, I.K.
Frontiers in Immunology 11 : 621556. 2 December 2020

CD40 provides immune privilege to the bone marrow hematopoietic niche.
Bassani, B., Gulino, A., Portararo, P., Botti, L., Cappetti, B., Chiodoni, C., Bolli, N., Ciciarello, M., Joehrens, K., Anagnostopoulos, I., Na, I.K., Curti, A., Tripodo, C., Colombo, M.P. and Sangaletti, S.
bioRxiv : 2020.08.10.243691. 10 August 2020

2019

A Phase I/II first-line study of R-CHOP plus B-cell receptor/NF-κB-double-targeting to molecularly assess therapy response.
Denker, S., Bittner, A., Na, I.K., Kase, J., Frick, M., Anagnostopoulos, I., Hummel, M. and Schmitt, C.A.
International Journal of Hematologic Oncology 8 (4): IJH20. 19 December 2019

Cytotoxic effects of rabbit anti-thymocyte globulin preparations on primary human thymic epithelial cells.
Kaebisch, E.M., Cho, M.Y., Oh, Y.S., Olfe, L.I., Szyska, M., Becker, S.C., Reinke, P., Volk, H.D., Gillissen, B., Bullinger, L., Thiel, A. and Na, I.K.
Transplantation 103 (11): 2234-2244. November 2019

Chaperone protein HSC70 regulates intercellular transfer of Y chromosome antigen DBY.
Kretschmann, S., Herda, S., Bruns, H., Russ, J., van der Meijden, E.D., Schlötzer-Schrehardt, U., Griffioen, M., Na, I.K., Mackensen, A. and Kremer, A.N.
Journal of Clinical Investigation 129 (7): 2952-2963. 1 July 2019

Current clinical practice and challenges in the management of secondary immunodeficiency in hematological malignancies.
Na, I.K., Buckland, M., Agostini, C., Edgar, J.D.M., Friman, V., Michallet, M., Sánchez-Ramón, S., Scheibenbogen, C. and Quinti, I.
European Journal of Haematology 102 (6): 447-456. June 2019

2018

Nrf2 regulates CD4(+) T cell-induced acute graft-versus-host disease in mice.
Tsai, J.J., Velardi, E., Shono, Y., Argyropoulos, K.V., Holland, A.M., Smith, O.M., Yim, N.L., Rao, U.K., Kreines, F.M., Lieberman, S.R., Young, L.F., Lazrak, A., Youssef, S., Fu, Y.Y., Liu, C., Lezcano, C., Murphy, G.F., Na, I.K., Jenq, R.R., Hanash, A.M., Dudakov, J.A. and van den Brink, M.R.M.
Blood 132 (26): 2763-2774. 27 December 2018

A comparative analysis of human bone marrow-resident and peripheral memory B cells.
Becker, S.C., Szyska, M., Mensen, A., Hellwig, K., Otto, R., Olfe, L., Volk, H.D., Dörner, T., Dörken, B., Scheibenbogen, C., Schröder, J., Hocke, A.C. and Na, I.K.
Journal of Allergy and Clinical Immunology 141 (5): 1911-1913. May 2018

Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells.
Hammer, Q., Rückert, T., Borst, E.M., Dunst, J., Haubner, A., Durek, P., Heinrich, F., Gasparoni, G., Babic, M., Tomic, A., Pietra, G., Nienen, M., Blau, I.W., Hofmann, J., Na, I.K., Prinz, I., Koenecke, C., Hemmati, P., Babel, N., Arnold, R., Walter, J., Thurley, K., Mashreghi, M.F., Messerle, M. and Romagnani, C.
Nature Immunology 19 (5): 453-463. May 2018

A transgenic dual-luciferase reporter mouse for longitudinal and functional monitoring of T cells in vivo.
Szyska, M., Herda, S., Althoff, S., Heimann, A., Russ, J., D'Abundo, D., Dang, T.M., Durieux, I., Dörken, B., Blankenstein, T. and Na, I.K.
Cancer Immunology Research 6 (1): 110-120. January 2018

2017

Predictive significance of the European LeukemiaNet classification of genetic aberrations in patients with acute myeloid leukemia undergoing allogeneic stem cell transplantation.
Hemmati, P.G., Vuong, L.G., Terwey, T.H., Jehn, C.F., Le Coutre, P., Penack, O., Na, I.K., Dörken, B. and Arnold, R.
European Journal of Haematology 98 (2): 160-168. February 2017

2016

Bone marrow GvHD after allogeneic hematopoietic stem cell transplantation.
Szyska, M. and Na, I.K.
Frontiers in Immunology 7 : 118. 30 March 2016

2015

Allogeneic stem cell transplantation for refractory acute myeloid leukemia: a single center analysis of long-term outcome.
Hemmati, P.G., Terwey, T.H., Na, I.K., Jehn, C.F., le Coutre, P., Vuong, L.G., Doerken, B. and Arnold, R.
European Journal of Haematology 95 (6): 498-506. December 2015

Altered B-cell subsets and functional B-cell defects in selective IgM deficiency.
Mensen, A., Krause, T., Hanitsch, L.G., Meisel, C., Kleint, M.E., Volk, H.D., Na, I.K. and Scheibenbogen, C.
Clinical Immunology 161 (2): 96-102. December 2015

Apoptosis-susceptibility prolongs the lack of memory B cells in acute leukemic patients after allogeneic hematopoietic stem cell transplantation.
Mensen, A., Oh, Y., Becker, S.C., Hemmati, P.G., Jehn, C., Westermann, J., Szyska, M., Göldner, H., Dörken, B., Scheibenbogen, C., Arnold, R. and Na, I.K.
Biology of Blood and Marrow Transplantation 21 (11): 1895-1906. November 2015

Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multi-center survey.
Zeiser, R., Burchert, A., Lengerke, C., Verbeek, M., Maas-Bauer, K., Metzelder, S.K., Spoerl, S., Ditschkowski, M., Ecsedi, M., Sockel, K., Ayuk, F., Ajib, S., de Fontbrune, F.S., Na, I.K., Penter, L., Holtick, U., Wolf, D., Schuler, E., Meyer, E., Apostolova, P., Bertz, H., Marks, R., Lübbert, M., Wäsch, R., Scheid, C., Stölzel, F., Ordemann, R., Bug, G., Kobbe, G., Negrin, R., Brune, M., Spyridonidis, A., Schmitt-Gräff, A., van der Velden, W., Huls, G., Mielke, S., Grigoleit, G.U., Kuball, J., Flynn, R., Ihorst, G., Du, J., Blazar, B.R., Arnold, R., Kröger, N., Passweg, J., Halter, J., Socie, G., Beelen, D., Peschel, C., Neubauer, A., Finke, J., Duyster, J. and von Bubnoff, N.
Leukemia 29 (10): 2062-2068. October 2015

Emerging role of tyrosine kinases as drugable targets in cancer.
Na, I.K. and Le Coutre, P.
Biomarker Insights 10 (S3): 29-31. 10 September 2015

Impact of early remission by induction therapy on allogeneic stem cell transplantation for acute myeloid leukemia with an intermediate risk karyotype in first complete remission.
Hemmati, P.G., Terwey, T.H., Na, I.K., le Coutre, P., Jehn, C.F., Vuong, L.G., Dörken, B. and Arnold, R.
European Journal of Haematology 94 (5): 431-438. May 2015

2014

Comparison of different rabbit ATG preparation effects on early lymphocyte subset recovery after allogeneic HSCT and its association with EBV-mediated PTLD.
Mensen, A., Na, I.K., Häfer, R., Meerbach, A., Schlecht, M., Pietschmann, M.L. and Gruhn, B.
Journal of Cancer Research and Clinical Oncology 140 (11): 1971-1980. November 2014

Bone marrow T-cell infiltration during acute GVHD is associated with delayed B-cell recovery and function after HSCT.
Mensen, A., Jöhrens, K., Anagnostopoulos, I., Demski, S., Oey, M., Stroux, A., Hemmati, P., Westermann, J., Blau, O., Wittenbecher, F., Movassaghi, K., Szyska, M., Thomas, S., Dörken, B., Scheibenbogen, C., Arnold, R. and Na, I.K.
Blood 124 (6): 963-972. 7 August 2014

2013

Rabbit antithymocyte globulin induces rapid expansion of effector memory CD8 T cells without accelerating acute graft versus host disease.
Wittenbecher, F., Rieger, K., Dziubianau, M., Herholz, A., Mensen, A., Blau, I.W., Uharek, L., Dörken, B., Thiel, A. and Na, I.K.
Leukemia Research Reports 2 (2): 82-85. 27 September 2013

Utilization of TREC and KREC quantification for the monitoring of early T- and B-cell neogenesis in adult patients after allogeneic hematopoietic stem cell transplantation.
Mensen, A., Ochs, C., Stroux, A., Wittenbecher, F., Szyska, M., Imberti, L., Fillatreau, S., Uharek, L., Arnold, R., Dörken, B., Thiel, A., Scheibenbogen, C. and Na, I.K.
Journal of Translational Medicine 11 (1): 188. 14 August 2013

PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating graft-versus-host-disease.
Ghosh, A., Holland, A.M., Dogan, Y., Yim, N., Rao, U.K., Young, L.F., West, M.L., Singer, N.V., Lee, H., Na, I.K., Tsai, J.J., Jenq, R., Penack, O., Hanash, A.M., Lezcano, C., Murphy, G.F., Liu, C., Sadelain, M., Sauer, M.G., Sant'Angelo, D. and van den Brink, M.R.M.
Cancer Research 73 (15): 4687-4696. 1 August 2013

Rabbit antithymocyte globulin (Thymoglobulin(R)) impairs the thymic output of both conventional and regulatory CD4(+) T cells after allogeneic hematopoietic stem cell transplantation in adult patients.
Na, I.K., Wittenbecher, F., Dziubianau, M., Herholz, A., Mensen, A., Kunkel, D., Blau, O., Blau, I., Thiel, E., Uharek, L., Scheibenbogen, C., Rieger, K. and Thiel, A.
Haematologica 98 (1): 23-30. January 2013

2011

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL.
Hanash, A.M., Kappel, L.W., Yim, N.L., Nejat, R.A., Goldberg, G.L., Smith, O.M., Rao, U.K., Dykstra, L., Na, I.K., Holland, A.M., Dudakov, J.A., Liu, C., Murphy, G.F., Leonard, W.J., Heller, G. and van den Brink, M.R.M.
Blood 118 (2): 446-455. 14 July 2011

Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation.
Lu, S.X., Kappel, L.W., Charbonneau-Allard, A.M., Atallah, R., Holland, A.M., Turbide, C., Hubbard, V.M., Rotolo, J.A., Smith, M., Suh, D., King, C., Rao, U.K., Yim, N., Bautista, J.L., Jenq, R.R., Penack, O., Na, I.K., Liu, C., Murphy, G., Alpdogan, O., Blumberg, R.S., Macian, F., Holmes, K.V., Beauchemin, N. and van den Brink, M.R.M.
PLoS ONE 6 (7): e21611. 6 July 2011

2010

Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo.
Na, I.K., Markley, J.C., Tsai, J.J., Yim, N.L., Beattie, B.J., Klose, A.D., Holland, A.M., Ghosh, A., Rao, U.K., Stephan, M.T., Serganova, I., Santos, E.B., Brentjens, R.J., Blasberg, R.G., Sadelain, M. and van den Brink, M.R.M.
Blood 116 (11): e18-e25. 16 September 2010

Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease.
Lu, S.X., Holland, A.M., Na, I.K., Terwey, T.H., Alpdogan, O., Bautista, J.L., Smith, O.M., Suh, D., King, C., Kochman, A., Hubbard, V.M., Rao, U.K., Yim, N., Liu, C., Laga, A.C., Murphy, G., Jenq, R.R., Zakrzewski, J.L., Penack, O., Dykstra, L., Bampoe, K., Perez, L., Furie, B., Furie, B. and van den Brink, M.R.M.
Journal of Immunology 185 (3): 1912-1919. 1 August 2010

Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth.
Penack, O., Henke, E., Suh, D., King, C.G., Smith, O.M., Na, I.K., Holland, A.M., Ghosh, A., Lu, S.X., Jenq, R.R., Liu, C., Murphy, G.F., Lu, T.T., May, C., Scheinberg, D.A., Gao, D.C., Mittal, V., Heller, G., Benezra, R. and van den Brink, M.R.M.
Journal of the National Cancer Institute 102 (12): 894-908. 16 June 2010

Human peripheral blood and bone marrow Epstein-Barr virus-specific T-cell repertoire in latent infection reveals distinct memory T-cell subsets.
Guerreiro, M., Na, I.K., Letsch, A., Haase, D., Bauer, S., Meisel, C., Roemhild, A., Reinke, P., Volk, H.D. and Scheibenbogen, C.
European Journal of Immunology 40 (6): 1566-1576. June 2010

The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease.
Na, I.K., Lu, S.X., Yim, N.L., Goldberg, G.L., Tsai, J., Rao, U., Smith, O.M., King, C.G., Suh, D., Hirschhorn-Cymerman, D., Palomba, L., Penack, O., Holland, A.M., Jenq, R.R., Ghosh, A., Tran, H., Merghoub, T., Liu, C., Sempowski, G.D., Ventevogel, M., Beauchemin, N. and van den Brink, M.R.M.
Journal of Clinical Investigation 120 (1): 343-356. January 2010

2009

Human bone marrow as a source to generate CMV-specific CD4+ T cells with multifunctional capacity.
Na, I.K., Letsch, A., Guerreiro, M., Bauer, S., Noack, I., Geginat, J., Reinke, P., Loesch, M., Kienapfel, H., Thiel, E., Volk, H.D. and Scheibenbogen, C.
Journal of Immunotherapy 32 (9): 907-913. November 2009

NOD2 regulates hematopoietic cell function during graft-versus-host disease.
Penack, O., Smith, O.M., Cunningham-Bussel, A., Liu, X., Rao, U., Yim, N., Na, I.K., Holland, A.M., Ghosh, A., Lu, S.X., Jenq, R.R., Liu, C., Murphy, G.F., Brandl, K. and van den Brink, M.R.M.
Journal of Experimental Medicine 206 (10): 2101-2110. 28 September 2009

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation.
Jenq, R.R., King, C.G., Volk, C., Suh, D., Smith, O.M., Rao, U.K., Yim, N.L., Holland, A.M., Lu, S.X., Zakrzewski, J.L., Goldberg, G.L., Diab, A., Alpdogan, O., Penack, O., Na, I.K., Kappel, L.W., Wolchok, J.D., Houghton, A.N., Perales, M.A. and van den Brink, M.R.M.
Blood 113 (7): 1574-1580. 12 February 2009

2008

Nuclear expression of CXCR4 in tumor cells of non-small cell lung cancer is correlated with lymph node metastasis.
Na, I.K., Scheibenbogen, C., Adam, C., Stroux, A., Ghadjar, P., Thiel, E., Keilholz, U. and Coupland, S.E.
Human Pathology 39 (12): 1751-1755. December 2008

Identification of truncated chemokine receptor 7 in human colorectal cancer unable to localize to the cell surface and unreactive to external ligands.
Na, I.K., Busse, A., Scheibenbogen, C., Ghadjar, P., Coupland, S.E., Letsch, A., Loddenkemper, C., Stroux, A., Bauer, S., Thiel, E. and Keilholz, U.
International Journal of Cancer 123 (7): 1565-1572. 1 October 2008

Sensitivity of tumor cells to proteasome inhibitors is associated with expression levels and composition of proteasome subunits.
Busse, A., Kraus, M., Na, I.K., Rietz, A., Scheibenbogen, C., Driessen, C., Blau, I.W., Thiel, E. and Keilholz, U.
Cancer 112 (3): 659-670. 1 February 2008

2007

CMV-specific central memory T cells reside in bone marrow.
Letsch, A., Knoedler, M., Na, I.K., Kern, F., Asemissen, A.M., Keilholz, U., Loesch, M., Thiel, E., Volk, H.D. and Scheibenbogen, C.
European Journal of Immunology 37 (11): 3063-3068. November 2007

Addition of GM-CSF to a peptide/KLH vaccine results in increased frequencies of CXCR3-expressing KLH-specific T cells.
Na, I.K., Keilholz, U., Letsch, A., Bauer, S., Asemissen, A.M., Nagorsen, D., Thiel, E. and Scheibenbogen, C.
Cancer Immunology Immunotherapy 56 (3): 391-396. March 2007

2006

Developmental stage-specific shift in responsiveness to chemokines during human B-cell development.
Honczarenko, M., Glodek, A.M., Swierkowski, M., Na, I.K. and Silberstein, L.E.
Experimental Hematology 34 (8): 1093-1100. August 2006

Chemokine receptor CCR6 expression level and liver metastases in colorectal cancer.
Ghadjar, P., Coupland, S.E., Na, I.K., Noutsias, M., Letsch, A., Stroux, A., Bauer, S., Buhr, H.J., Thiel, E., Scheibenbogen, C. and Keilholz, U.
Journal of Clinical Oncology 24 (12): 1910-1916. 20 April 2006

Lymphomas are sensitive to perforin-dependent cytotoxic pathways despite expression of PI-9 and overexpression of bcl-2.
Godal, R., Keilholz, U., Uharek, L., Letsch, A., Asemissen, A.M., Busse, A., Na, I.K., Thiel, E. and Scheibenbogen, C.
Blood 107 (8): 3205-3211. 15 April 2006

2005

Expression of the chemokine receptors CXCR4, CXCR5, and CCR7 in primary central nervous system lymphoma.
Jahnke, K., Coupland, S.E., Na, I.K., Loddenkemper, C., Keilholz, U., Korfel, A., Stein, H., Thiel, E. and Scheibenbogen, C.
Blood 106 (1): 384-385. 1 July 2005

Imatinib mesylate radiosensitizes human glioblastoma cells through inhibition of platelet-derived growth factor receptor.
Holdhoff, M., Kreuzer, K.A., Appelt, C., Scholz, R., Na, I.K., Hildebrandt, B., Riess, H., Jordan, A., Schmidt, C.A., Van Etten, R.A., Doerken, B. and LeCoutre, P.
Blood Cells Molecules and Diseases 34 (2): 181-185. 1 March 2005

Quantitative RT-PCR of Wilms tumor gene transcripts (WT1) for the molecular monitoring of patients with accelerated phase bcr/abl + CML.
Na, I.K., Kreuzer, K.A., Lupberger, J., Doerken, B. and Coutre, P.
Leukemia Research Reports 29 (3): 343-345. 1 March 2005

2003

Imatinib in Philadelphia chromosome-positive chronic phase CML patients: molecular and cytogenetic response rates and prediction of clinical outcome.
Le Coutre, P., Kreuzer, K.A., Na, I.K., Schwarz, M., Lupberger, J., Holdhoff, M., Baskaynak, G., Gschaidmeier, H., Platzbecker, U., Ehninger, G., Prejzner, W., Huhn, D. and Schmidt, C.A.
American Journal of Hematology 73 (4): 249-255. August 2003

Preexistence and evolution of imatinib mesylate-resistant clones in chronic myelogenous leukemia detected by a PNA-based PCR clamping technique.
Kreuzer, K.A., Le Coutre, P., Landt, O., Na, I.K., Schwarz, M., Schultheis, K., Hochhaus, A. and Doerken, B.
Annals of Hematology 82 (5): 284-289. May 2003

2002

Determination of alpha-1 acid glycoprotein in patients with Ph+ chronic myeloid leukemia during the first 13 weeks of therapy with STI571.
le Coutre, P., Kreuzer, K.A., Na, I.K., Lupberger, J., Holdhoff, M., Appelt, C., Schwarz, M., Mueller, C., Gambacorti-Passerini, C., Platzbecker, U., Bonnet, R., Ehninger, G. and Schmidt, C.A.
Blood Cells Molecules and Diseases 28 (1): 75-85. January 2002

2001

Fluorescent 5'-exonuclease assay for the absolute quantification of Wilms' tumour gene (WT1) mRNA: implications for monitoring human leukaemias.
Kreuzer, K.A., Saborowski, A., Lupberger, J., Appelt, C., Na, I.K., le Coutre, P. and Schmidt, C.A.
British Journal of Haematology 114 (2): 313-318. August 2001