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Article

Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders.
Lorenz, C., Lesimple, P., Bukowiecki, R., Zink, A., Inak, G., Mlody, B., Singh, M., Semtner, M., Mah, N., Auré, K., Leong, M., Zabiegalov, O., Lyras, E.M., Pfiffer, V., Fauler, B., Eichhorst, J., Wiesner, B., Huebner, N., Priller, J., Mielke, T., Meierhofer, D., Izsvák, Z., Meier, J.C., Bouillaud, F., Adjaye, J., Schuelke, M., Wanker, E.E., Lombès, A. and Prigione, A.
Cell Stem Cell 20 (5): 659-674.e9. 4 May 2017

Hippocampal characteristics and invariant sequence elements distribution of GLRA2 and GLRA3 C-to-U editing.
Schaefermeier, P. and Heinze, S.
Molecular Syndromology 8 (2): 85-92. March 2017

Identification of parvalbumin interneurons as cellular substrate of fear memory persistence.
Caliskan, G., Mueller, I., Semtner, M., Winkelmann, A., Raza, A.S., Hollnagel, J.O., Roesler, A., Heinemann, U., Stork, O. and Meier, J.C.
Cerebral Cortex 26 (5): 2325-2340. May 2016

Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.
Fossati, G., Morini, R., Corradini, I., Antonucci, F., Trepte, P., Edry, E., Sharma, V., Papale, A., Pozzi, D., Defilippi, P., Meier, J.C., Brambilla, R., Turco, E., Rosenblum, K., Wanker, E.E., Ziv, N.E., Menna, E. and Matteoli, M.
Cell Death and Differentiation 22 (9): 1425-1436. September 2015

Chloride transporter KCC2-dependent neuroprotection depends on the N-terminal protein domain.
Winkelmann, A., Semtner, M. and Meier, J.C.
Cell Death & Disease 6 : e1776. 4 June 2015

Rare variants in GABA(A) receptor genes in Rolandic epilepsy and related syndromes.
Reinthaler, E.M., Dejanovic, B., Lal, D., Semtner, M., Merkler, Y., Reinhold, A., Pittrich, D.A., Hotzy, C., Feucht, M., Steinboeck, H., Gruber-Sedlmayr, U., Ronen, G., Neophytou, B., Geldner, J., Haberlandt, E., Muhle, H., Ikram, M.A., van Duijn, CM., Uitterlinden, A.G., Hofman, A., Altmüller, J., Kawalia, A., Toliat, M.R., Nuernberg, P., Lerche, H., Nothnagel, M., Thiele, H., Sander, T., Meier, J.C., Schwarz, G., Neubauer, B.A. and Zimprich, F.
Annals of Neurology 77 (6): 972-986. June 2015

Identification of a new genomic hot spot of evolutionary diversification of protein function.
Winkelmann, A., You, X., Gruenewald, N., Haeussler, U., Krestel, H., Haas, C.A., Schwarz, G., Chen, W. and Meier, J.C.
PLoS ONE 10 (5): e0125413. 8 May 2015

Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum.
Staudacher, J.J., Naarmann-de Vries, I.S., Ujvari, S.J., Klinger, B., Kasim, M., Benko, E., Ostareck-Lederer, A., Ostareck, D.H., Bondke Persson, A., Lorenzen, S., Meier, J.C., Blüthgen, N., Persson, P.B., Henrion-Caude, A., Mrowka, R. and Faehling, M.
Nucleic Acids Research 43 (6): 3219-3236. 31 March 2015

Shutdown of achaete-scute homolog-1 expression by heterogeneous nuclear ribonucleoprotein (hnRNP)-A2/B1 in hypoxia.
Kasim, M., Benko, E., Winkelmann, A., Mrowka, R., Staudacher, J.J., Persson, P.B., Scholz, H., Meier, J.C. and Fahling, M.
Journal of Biological Chemistry 289 (39): 26973-26988. 26 September 2014

Intracellular glycine receptor function facilitates glioma formation in vivo.
Förstera, B., a Dzaye, O.D., Winkelmann, A., Semtner, M., Benedetti, B., Markovic, D.S., Synowitz, M., Wend, P., Fähling, M., Junier, M.P., Glass, R., Kettenmann, H. and Meier, J.C.
Journal of Cell Science 127 (Pt 17): 3687-3698. 1 September 2014

Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses.
Dejanovic, B., Semtner, M., Ebert, S., Lamkemeyer, T., Neuser, F., Luescher, B., Meier, J.C. and Schwarz, G.
PLoS Biology 12 (7): e1001908. 15 July 2014

Membrane distribution of the glycine receptor α3 studied by optical super-resolution microscopy.
Notelaers, K., Rocha, S., Paesen, R., Swinnen, N., Vangindertael, J., Meier, J.C., Rigo, J.M., Ameloot, M. and Hofkens, J.
Histochemistry and Cell Biology 142 (1): 79-90. July 2014

Analysis of α3 GlyR single particle tracking in the cell membrane.
Notelaers, K., Rocha, S., Paesen, R., Smisdom, N., De Clercq, B., Meier, J.C., Rigo, J.M., Hofkens, J. and Ameloot, M.
Biochimica et Biophysica Acta - Molecular Cell Research 1843 (3): 544-553. March 2014

Changes in neural network homeostasis trigger neuropsychiatric symptoms.
Winkelmann, A., Maggio, N., Eller, J., Caliskan, G., Semtner, M., Häussler, U., Jüttner, R., Dugladze, T., Smolinsky, B., Kowalczyk, S., Chronowska, E., Schwarz, G., Rathjen, F.G., Rechavi, G., Haas, C.A., Kulik, A., Gloveli, T., Heinemann, U. and Meier, J.C.
Journal of Clinical Investigation 124 (2): 696-711. 3 February 2014

Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3.
Wojtowicz, A.M., Dvorzhak, A., Semtner, M. and Grantyn, R.
Frontiers in Neural Circuits 7 : 188. 26 November 2013

GABA(B) autoreceptor-mediated cell type-specific reduction of inhibition in epileptic mice.
Dugladze, T., Maziashvili, N., Boergers, C., Gurgenidze, S., Haeussler, U., Winkelmann, A., Haas, C.A., Meier, J.C., Vida, I., Kopell, N.J. and Gloveli, T.
Proceedings of the National Academy of Sciences of the United States of America 110 (37): 15073-15078. 10 September 2013

New insights in endogenous modulation of ligand-gated ion channels: histamine is an inverse agonist at strychnine sensitive glycine receptors.
Kletke, O., Sergeeva, O.A., Lorenz, P., Oberland, S., Meier, J.C., Hatt, H. and Gisselmann, G.
European Journal of Pharmacology 710 (1-3): 59-66. 15 June 2013

Direct binding of GABA(A) receptor β2 and β3 subunits to gephyrin.
Kowalczyk, S., Winkelmann, A., Smolinsky, B., Foerstera, B., Neundorf, I., Schwarz, G. and Meier, J.C.
European Journal of Neuroscience 37 (4): 544-554. February 2013

Ensemble and single particle fluorimetric techniques in concerted action to study the diffusion and aggregation of the glycine receptor α3 isoforms in the cell plasma membrane.
Notelaers, K., Smisdom, N., Rocha, S., Janssen, D., Meier, J.C., Rigo, J.M., Hofkens, J. and Ameloot, M.
Biochimica et Biophysica Acta - Biomembranes 1818 (12): 3131-3140. December 2012

Phorbol-ester mediated suppression of hASH1 synthesis: multiple ways to keep the level down.
Benko, E., Winkelmann, A., Meier, J.C., Persson, P.B., Scholz, H. and Faehling, M.
Frontiers in Molecular Neuroscience 4 : 1. 2011

Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy.
Foerstera, B., Belaidi, A.A., Juettner, R., Bernert, C., Tsokos, M., Lehmann, T.N., Horn, P., Dehnicke, C., Schwarz, G. and Meier, J.C.
Brain 133 (Pt12): 3778-3794. December 2010

Glycine receptors caught between genome and proteome – Functional implications of RNA editing and splicing.
Legendre, P., Foerstera, B., Juettner, R. and Meier, J.C.
Frontiers in Molecular Neuroscience 2 : 23. 9 November 2009

Splice-specific roles of glycine receptor alpha3 in the hippocampus.
Eichler, S.A., Foerstera, B., Smolinsky, B., Juettner, R., Lehmann, T.N., Faehling, M., Schwarz, G., Legendre, P. and Meier, J.C.
European Journal of Neuroscience 30 (6): 1077-1091. September 2009

Translational regulation of the human achaete-scute homologue-1 (hASH1) by fragile x-mental retardation protein (FMRP).
Faehling, M., Mrowka, R., Steege, A., Kirschner, K.M., Benko, E., Foerstera, B., Persson, P.B., Thiele, B.J., Meier, J.C. and Scholz, H.
Journal of Biological Chemistry 284 (7): 4255-4266. 13 February 2009

Transferrin-receptor-mediated iron accumulation controls proliferation and glutamate release in glioma cells.
Chirasani, S.R., Markovic, D.S., Synowitz, M., Eichler, S.A., Wisniewski, P., Kaminska, B., Otto, A., Wanker, E., Schaefer, M., Chiarugi, P., Meier, J.C., Kettenmann, H. and Glass, R.
Journal of Molecular Medicine 87 (2): 153-167. February 2009

Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy.
Eichler, S.A., Kirischuk, S., Juettner, R., Schaefermeier, P.K., Legendre, P., Lehmann, T.N., Gloveli, T., Grantyn, R. and Meier, J.C.
Journal of Cellular and Molecular Medicine 12 (6b): 2848-2866. December 2008

Splice-specific functions of gephyrin in molybdenum cofactor biosynthesis.
Smolinsky, B., Eichler, S.A., Burchmeier, S., Meier, J.C. and Schwarz, G.
Journal of Biological Chemistry 283 (25): 17370-17379. 20 June 2008

E-I balance and human diseases - from molecules to networking.
Eichler, S.A. and Meier, J.C.
Frontiers in Molecular Neuroscience 1 (2) 28 March 2008

Vertebrate-specific sequences in the gephyrin E-domain regulate cytosolic aggregation and postsynaptic clustering.
Lardi-Studler, B., Smolinsky, B., Petitjean, C.M., Koenig, F., Sidler, C., Meier, J.C., Fritschy, J.M. and Schwarz, G.
Journal of Cell Science 120 (Pt 8): 1371-1382. 15 April 2007

Altered balance of glutamatergic/GABAergic synaptic input and associated changes in dendrite morphology after BDNF expression in BDNF-deficient hippocampal neurons.
Singh, B., Henneberger, C., Betances, D., Arevalo, M.A., Rodriguez-Tebar, A., Meier, J.C. and Grantyn, R.
Journal of Neuroscience 26 (27): 7189-7200. 5 July 2006

RNA editing produces glycine receptor alpha3(P185L), resulting in high agonist potency.
Meier, J.C., Henneberger, C., Melnick, I., Racca, C., Harvey, R.J., Heinemann, U., Schmieden, V. and Grantyn, R.
Nature Neuroscience 8 (6): 736-744. June 2005

Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity.
Juettner, R., More, M.I., Das, D., Babich, A., Meier, J., Henning, M., Erdmann, B., Mueller, E.C., Otto, A., Grantyn, R. and Rathjen, F.G.
Neuron 46 (2): 233-245. 21 May 2005

GluR- and TrkB-mediated maturation of GABA receptor function during the period of eye opening.
Henneberger, C., Juettner, R., Schmidt, S.A., Walter, J., Meier, J.C., Rothe, T. and Grantyn, R.
European Journal of Neuroscience 21 (2): 431-440. January 2005

NGF controls dendrite development in hippocampal neurons by binding to p75NTR and modulating the cellular targets of Notch.
Salama-Cohen, P., Arevalo, M.A., Meier, J., Grantyn, R. and Rodríguez-Tebar, A.
Molecular Biology of the Cell 16 (1): 339-347. January 2005

A gephyrin-related mechanism restraining glycine receptor anchoring at GABAergic synapses.
Meier, J. and Grantyn, R.
Journal of Neuroscience 24 (6): 1398-1405. 11 February 2004

Preferential accumulation of GABAA receptor gamma 2L, not gamma 2S, cytoplasmic loops at rat spinal cord inhibitory synapses.
Meier, J. and Grantyn, R.
Journal of Physiology 559 (Pt 2): 355-365. 2004

Inhibition of alpha-subunit glycine receptors by quinoxalines.
Meier, J. and Schmieden, V.
NeuroReport 14 (11): 1507-1510. 6 August 2003

GABA(A) receptor activity and PKC control inhibitory synaptogenesis in CNS tissue slices.
Meier, J., Akyeli, J., Kirischuk, S. and Grantyn, R.
Molecular and Cellular Neuroscience 23 (4): 600-613. August 2003

Desensitization of homomeric alpha1 glycine receptor increases with receptor density.
Legendre, P., Muller, E., Badiu, C.I., Meier, J., Vannier, C. and Triller, A.
Molecular Pharmacology 62 (4): 817-827. October 2002

Synaptic anchoring of glycine receptors in developing collicular neurons under control of metabotropic glutamate receptor activity.
Meier, J., Juettner, R., Kirischuk, S. and Grantyn, R.
Molecular and Cellular Neuroscience 21 (2): 324-340. October 2002

Dynamics of glycine receptor insertion in the neuronal plasma membrane.
Rosenberg, M., Meier, J., Triller, A. and Vannier, C.
Journal of Neuroscience 21 (14): 5036-5044. 15 July 2001

Slow IPSC kinetics, low levels of alpha1 subunit expression and paired-pulse depression are distinct properties of neonatal inhibitory GABAergic synaptic connections in the mouse superior colliculus.
Juettner, R., Meier, J. and Grantyn, R.
European Journal of Neuroscience 13 (11): 2088-2098. June 2001

Fast and reversible trapping of surface glycine receptors by gephyrin.
Meier, J., Vannier, C., Serge, A., Triller, A. and Choquet, D.
Nature Neuroscience 4 (3): 253-260. March 2001

Functional heterogeneity of gephyrins.
Meier, J., De Chaldee, M., Triller, A. and Vannier, C.
Molecular and Cellular Neuroscience 16 (5): 566-577. November 2000

Formation of glycine receptor clusters and their accumulation at synapses.
Meier, J., Meunier-Durmort, C., Forest, C., Triller, A. and Vannier, C.
Journal of Cell Science 113 (Pt 15): 2783-2795. August 2000

Book Section

Protein kinases and synaptogenesis.
Meier, J.C.
In: Molecular Mechanisms of Synaptogenesis. Springer, 311-332. ISBN 0-387-32560-3 2006

From synapses to maps: Development and use-dependent modification of synaptic connections in the visual layers of the rodent superior colliculus.
Grantyn, R., Juettner, R. and Meier, J.
In: Methods and New Frontiers in Neuroscience: The superior colliculus. CRC Press, 173-210. 2004

Review

Presynaptic mechanisms of neuronal plasticity and their role in epilepsy.
Meier, J.C., Semtner, M., Winkelmann, A. and Wolfart, J.
Frontiers in Cellular Neuroscience 8 : 164. 17 June 2014

Functional hallmarks of GABAergic synapse maturation and the diverse roles of neurotrophins.
Grantyn, R., Henneberger, C., Juettner, R., Meier, J.C. and Kirischuk, S.
Frontiers in Cellular Neuroscience 5 : 13. 4 July 2011

The enigma of transmitter-selective receptor accumulation at developing inhibitory synapses.
Meier, J.
Cell and Tissue Research 311 (3): 271-276. March 2003

Editorial

Frontiers in molecular neuroscience - resume and perspective.
Meier, J.C., Harvey, R.J. and Seeburg, P.
Frontiers in Molecular Neuroscience 4 : 58. December 2011

Genetic techniques and circuit analysis.
Wisden, W. and Meier, J.C.
Frontiers in Molecular Neuroscience 3 (3): 4. 3 March 2010