2026

Probing 3-amino-2H-azaindazoles as allosteric inhibitors of the protein tyrosine phosphatase SHP2.
Amoussa, Machoud, Efrém, Nina-Louisa, Li, Feng, Guo, Ziqiong, Roske, Yvette ORCID: https://orcid.org/0000-0001-6237-388X, Frank, Katrin Jana, Pach, Szymon, Wolf, Clemens Alexander, Bo, Feng, Lesina, Marina, Kintzel, Mika, Alsalim, Rana, Zeitz, Victoria, Csorba, Noémi, Radetzki, Silke ORCID: https://orcid.org/0000-0003-2688-2868, Keserű, György M., Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414, Algül, Hana, Wolber, Gerhard, Li, Jia and Nazaré, Marc ORCID: https://orcid.org/0000-0002-1602-2330
ChemMedChem 21 (11): e70341. 15 June 2026

Crystal structure of 3-hydroxypropionyl-CoA synthetase (ADP-forming) from Nitrosopumilus maritimus.
Johnson, Jerome, Tosun, Bilge, Yilmaz, Merve, Tolar, Bradley B., Yoshikuni, Yasuo, Francis, Christopher A., Doukov, Tzanko, Yokoi, Shun, Wakatsuki, Soichi and DeMirci, Hasan
Current Research in Structural Biology 11 : 100189. June 2026

Mapping the SHP2 allosteric pocket with target-biased covalent fragments.
Efrém, Nina-Louisa, Csorba, Noémi, Amoussa, Machoud, Ábrányi-Balogh, Péter, Guo, Ziqiong, Petri, László, Bo, Feng, Di Lorenzo, Vincenzo, Roske, Yvette ORCID: https://orcid.org/0000-0001-6237-388X, Szalai, Tibor Viktor ORCID: https://orcid.org/0009-0000-4088-3117, Mihalovits, Levente, Simon, József, Li, Jia, Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414, Keserű, György M. and Nazaré, Marc ORCID: https://orcid.org/0000-0002-1602-2330
ChemBioChem 27 (8): e70310. April 2026

Conservation and specificity in Bacillus biofilm dynamics: on structure and function of B. cereus Camelysins.
Diehl, Anne, Lindemann, Florian, Cremer, Nils, Roske, Yvette ORCID: https://orcid.org/0000-0001-6237-388X, Hiller, Matthias, van Rossum, Barth, Leidert, Martina, Turgay, Kürşad and Oschkinat, Hartmut
Journal of Molecular Biology 438 (6): 169661. 15 March 2026

3-hydroxypropionyl-CoA Synthetase (ADP-forming) from Nitrosopumilus maritimus.
Johnson, J.A., Yilmaz, M., Tosun, B., Wakatsuki, S. and Demirci, H.
[Dataset] 11 March 2026

Towards crystal structures of filament forming proteins.
Roske, Yvette ORCID: https://orcid.org/0000-0001-6237-388X, Leidert, Martina, Rehbein, Kristina and Diehl, Anne ORCID: https://orcid.org/0000-0001-7295-9972
bioRxiv : 2026.02.22.707290. 22 February 2026

Effect of temperature ramp in rapid folding of 3D DNA origami structures.
Dey, Anurit ORCID: https://orcid.org/0009-0004-2272-5544, Al Hussain, Mohammed Mustafa A. ORCID: https://orcid.org/0000-0001-7132-8482, Pham, Xuan‐Hung ORCID: https://orcid.org/0000-0002-4927-7102, Loo, Jacky ORCID: https://orcid.org/0000-0002-0355-8865, Natarajan, Ashwin Karthick ORCID: https://orcid.org/0000-0001-7897-708X and Kuzyk, Anton ORCID: https://orcid.org/0000-0001-8060-6122
Small Structures 7 (2): e202500682. February 2026

Integrative modelling reveals the structure of the human Mic60-Mic19 subcomplex and its role as a diffusion barrier in mitochondria.
Nathanail, Evangelia ORCID: https://orcid.org/0009-0004-9579-8074, Rolando, Edoardo ORCID: https://orcid.org/0009-0001-8276-1406, Ruwolt, Max ORCID: https://orcid.org/0009-0000-7220-406X, Zaporozhets, Iryna, Liu, Fan ORCID: https://orcid.org/0000-0002-2358-549X, Clementi, Cecilia ORCID: https://orcid.org/0000-0001-9221-2358 and Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414
bioRxiv : 2026.01.30.702776. 30 January 2026

2025

Structural studies suggest CCDC127 as a novel membrane contact site protein in the mitochondrial intermembrane space.
Bock-Bierbaum, Tobias ORCID: https://orcid.org/0000-0003-0843-2716, von der Malsburg, Karina, Natarajan, Ashwin Karthick ORCID: https://orcid.org/0000-0001-7897-708X, Zarges, Christine, Akkaya, Kerem Can, Aladawi, Amjad, Noll, Katja, Jungbluth, Sibylle, Schirra, Claudia, Zhu, Ying, Cremer, Nils, Bernert, Carola, Liu, Fan ORCID: https://orcid.org/0000-0002-2358-549X, Lehmann, Martin ORCID: https://orcid.org/0000-0002-8370-6353, Riemer, Jan ORCID: https://orcid.org/0000-0002-7574-8457, van der Laan, Martin ORCID: https://orcid.org/0000-0003-0789-9912 and Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414
bioRxiv : 2025.12.11.693622. 16 December 2025

Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons.
Kroll, Jana ORCID: https://orcid.org/0000-0003-4243-4088, Kravčenko, Uljana ORCID: https://orcid.org/0009-0004-7176-8444, Sadeghi, Mohsen ORCID: https://orcid.org/0000-0002-7698-5630, Diebolder, Christoph A. ORCID: https://orcid.org/0000-0001-7694-7362, Ivanov, Lia, Lubas, Małgorzata, Sprink, Thiemo ORCID: https://orcid.org/0000-0002-0760-6828, Schacherl, Magdalena ORCID: https://orcid.org/0000-0002-5478-2509, Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274 and Rosenmund, Christian ORCID: https://orcid.org/0000-0002-3905-2444
Nature Communications 16 (1): 11131. 15 December 2025

Topology control by a conserved cysteine pair in the OMM-protein CCDC127 enables MICOS interaction.
Zarges, Christine, Schepsky, Pauline, Rothemann, Robin Alexander, Bock-Bierbaum, Tobias ORCID: https://orcid.org/0000-0003-0843-2716, von der Malsburg, Alexander, Baumann, Linda, Trifunovic, Aleksandra ORCID: https://orcid.org/0000-0002-5472-3517, Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414, van der Laan, Martin ORCID: https://orcid.org/0000-0003-0789-9912, von der Malsburg, Karina and Riemer, Jan ORCID: https://orcid.org/0000-0002-7574-8457
bioRxiv : 2025.12.12.693940. 15 December 2025

Molecular machineries shaping the mitochondrial inner membrane.
Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and van der Laan, M. ORCID: https://orcid.org/0000-0003-0789-9912
Nature Reviews Molecular Cell Biology 26 (9): 706-724. September 2025

Detergent-free reconstitution of transmembrane proteins in giant liposomes of complex curvature by the Synthetic Membrane Transfer.
Meena, Hemraj, Zdanowicz, Rafal ORCID: https://orcid.org/0009-0005-5694-2704, Bock-Bierbaum, Tobias ORCID: https://orcid.org/0000-0003-0843-2716, Stephan, Till ORCID: https://orcid.org/0000-0002-4032-7644, Ottsen Knudsen, Sofie Dorothea, Jakobs, Stefan ORCID: https://orcid.org/0000-0002-8028-3121, Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414, Pedersen, Per A. and De Franceschi, Nicola ORCID: https://orcid.org/0000-0002-7221-613X
bioRxiv : 2025.08.23.671895. 23 August 2025

Structures of EHD2 filaments on curved membranes provide a model for caveolar neck stabilization.
Vázquez-Sarandeses, E., Mikirtumov, V. ORCID: https://orcid.org/0009-0004-6849-4825, Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
bioRxiv : 2025.06.05.658037. 7 June 2025

Penta-ALFA-tagged substrates for self-labelling tags allow signal enhancement in microscopy.
Ghosh, S. ORCID: https://orcid.org/0000-0003-1224-5008, Birke, R., Natarajan, A.K. ORCID: https://orcid.org/0000-0001-7897-708X and Broichhagen, J. ORCID: https://orcid.org/0000-0003-3084-6595
Journal of Peptide Science 31 (5): e70015. May 2025

Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy.
Escobar, H. ORCID: https://orcid.org/0000-0002-8128-7845, Di Francescantonio, S. ORCID: https://orcid.org/0000-0002-4815-491X, Smirnova, J., Graf, R. ORCID: https://orcid.org/0000-0002-5400-9938, Müthel, S. ORCID: https://orcid.org/0000-0002-3525-8859, Marg, A. ORCID: https://orcid.org/0000-0003-3673-4244, Zhogov, A., Krishna, S. ORCID: https://orcid.org/0009-0008-8974-0721, Metzler, E. ORCID: https://orcid.org/0000-0003-1735-6364, Petkova, M., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803 and Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117
Nature Communications 16 (1): 120. 2 January 2025

2024

Generation of effective and specific human TCRs against tumor/testis antigen NY-ESO-1 in mice with humanized T cell recognition system.
Chen, X.T. ORCID: https://orcid.org/0000-0002-5614-1406, Leisegang, M. ORCID: https://orcid.org/0000-0003-3692-7142, Gavvovidis, I. ORCID: https://orcid.org/0000-0001-5644-9788, Pollack, S.M., Lorenz, F.K.M. ORCID: https://orcid.org/0000-0001-7826-0839, Schumacher, T.N., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Frontiers in Immunology 15 : 1524629. 24 December 2024

Molecular architecture of synaptic vesicles.
Kravčenko, U. ORCID: https://orcid.org/0009-0004-7176-8444, Ruwolt, M., Kroll, J. ORCID: https://orcid.org/0000-0003-4243-4088, Yushkevich, A. ORCID: https://orcid.org/0000-0002-8729-9281, Zenkner, M., Ruta, J. ORCID: https://orcid.org/0009-0007-0524-6885, Lotfy, R., Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630, Rosenmund, C. ORCID: https://orcid.org/0000-0002-3905-2444, Liu, F. and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
Proceedings of the National Academy of Sciences of the United States of America 121 (49): e2407375121. 3 December 2024

Sociality shapes mitochondrial adaptations supporting hypoxia tolerance.
Rossi, A. ORCID: https://orcid.org/0000-0002-8819-9813, Ruwolt, M. ORCID: https://orcid.org/0009-0000-7220-406X, Kakouri, P., Kosten, T., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Puchkov, D. ORCID: https://orcid.org/0000-0001-8341-4847, Reznick, J. ORCID: https://orcid.org/0000-0001-7921-5466, Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Omerbašić, D. ORCID: https://orcid.org/0000-0003-1839-4856, Méndez Aranda, D. ORCID: https://orcid.org/0000-0001-9668-941X, Carai, G., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Hart, D.W. ORCID: https://orcid.org/0000-0002-4592-558X, Carraro, M. ORCID: https://orcid.org/0000-0002-4573-9306, Tommasin, L. ORCID: https://orcid.org/0000-0002-6029-0375, Bennett, N.C. ORCID: https://orcid.org/0000-0001-9748-2947, Bégay, V. ORCID: https://orcid.org/0000-0002-9002-4211, Faelber, K., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Bernardi, P. ORCID: https://orcid.org/0000-0001-9187-3736, Park, T.J. ORCID: https://orcid.org/0000-0002-2447-2948, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Liu, F. and Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352
bioRxiv : 2024.09.30.615914. 2 October 2024

Structure-based humanization of a therapeutic antibody for multiple myeloma.
Marino, S.F. ORCID: https://orcid.org/0000-0001-5696-9679 and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
Journal of Molecular Medicine 102 (9): 1151-1161. September 2024

Structural characterization of Thogoto Virus nucleoprotein provides insights into viral RNA encapsidation and RNP assembly.
Dick, A. ORCID: https://orcid.org/0000-0003-0580-1897, Mikirtumov, V. ORCID: https://orcid.org/0009-0004-6849-4825, Fuchs, J., Krupp, F. ORCID: https://orcid.org/0000-0002-0402-8647, Olal, D., Bendl, E., Sprink, T. ORCID: https://orcid.org/0000-0002-0760-6828, Diebolder, C. ORCID: https://orcid.org/0000-0001-7694-7362, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274, Kochs, G., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
Structure 32 (8): 1068-1078. 8 August 2024

Identification of drug-like molecules targeting the ATPase activity of dynamin-like EHD4.
Mohd, S., Oder, A., Specker, E. ORCID: https://orcid.org/0000-0002-9471-9520, Neuenschwander, M. ORCID: https://orcid.org/0000-0002-3114-7975, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988 and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
PLoS ONE 19 (7): e0302704. 29 July 2024

Fraternal twins at work: Structures of PLD3/4 reveal mechanism for lysosomal nucleic acid breakdown.
Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Damme, M.
Structure 32 (6): 645-647. 6 June 2024

Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T. ORCID: https://orcid.org/0000-0002-9075-103X, Meyer, K. ORCID: https://orcid.org/0000-0002-8244-6887, Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Ishihama, Y., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Nature Communications 15 (1): 3146. 11 April 2024

Structural insights into the activation mechanism of antimicrobial GBP1.
Weismehl, M. ORCID: https://orcid.org/0000-0001-7583-9095, Chu, X. ORCID: https://orcid.org/0000-0001-6801-3949, Kutsch, M. ORCID: https://orcid.org/0000-0002-9346-2196, Lauterjung, P., Herrmann, C. ORCID: https://orcid.org/0000-0002-1824-3647, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
EMBO Journal 43 (4): 615-636. 15 February 2024

GIMAP5 deficiency reveals a mammalian ceramide-driven longevity assurance pathway.
Park, A.Y. ORCID: https://orcid.org/0000-0002-0130-1521, Leney-Greene, M., Lynberg, M., Gabrielski, J.Q. ORCID: https://orcid.org/0000-0002-2953-2874, Xu, X., Schwarz, B., Zheng, L., Balasubramaniyam, A. ORCID: https://orcid.org/0000-0003-4168-8617, Ham, H. ORCID: https://orcid.org/0000-0002-8669-6875, Chao, B., Zhang, Y., Matthews, H.F., Cui, J., Yao, Y., Kubo, S. ORCID: https://orcid.org/0000-0001-9693-9263, Chanchu, J.M. ORCID: https://orcid.org/0009-0009-8024-8412, Morawski, A.R. ORCID: https://orcid.org/0000-0001-5995-0527, Cook, S.A., Jiang, P., Ravell, J.C., Cheng, Y.H., George, A., Faruqi, A. ORCID: https://orcid.org/0000-0002-4421-3767, Pagalilauan, A.M., Bergerson, J.R.E., Ganesan, S., Chauvin, S.D. ORCID: https://orcid.org/0000-0003-0232-751X, Aluri, J., Edwards-Hicks, J., Bohrnsen, E., Tippett, C., Omar, H., Xu, L., Butcher, G.W., Pascall, J., Karakoc-Aydiner, E., Kiykim, A., Maecker, H. ORCID: https://orcid.org/0000-0003-0795-9946, Tezcan, İ., Esenboga, S., Heredia, R.J., Akata, D., Tekin, S. ORCID: https://orcid.org/0000-0003-2641-6293, Kara, A. ORCID: https://orcid.org/0000-0001-7244-5031, Kuloglu, Z., Unal, E., Kendirli, T., Dogu, F., Karabiber, E., Atkinson, T.P., Cochet, C., Filhol, O. ORCID: https://orcid.org/0000-0003-1964-7958, Bosio, C.M., Davis, M.M. ORCID: https://orcid.org/0000-0001-6868-657X, Lifton, R.P., Pearce, E.L. ORCID: https://orcid.org/0000-0001-5592-5439, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Aytekin, C. ORCID: https://orcid.org/0000-0002-2921-5270, Şahin, G.E., Aksu, A.Ü., Uzel, G., Koneti Rao, V. ORCID: https://orcid.org/0000-0002-7881-6902, Sari, S., Boztug, K., Cagdas, D., Haskologlu, S. ORCID: https://orcid.org/0000-0002-2668-0441, Ikinciogullari, A., Schwefel, D., Vilarinho, S., Baris, S. ORCID: https://orcid.org/0000-0002-4730-9422, Ozen, A., Su, H.C. ORCID: https://orcid.org/0000-0002-5582-9110 and Lenardo, M.J. ORCID: https://orcid.org/0000-0003-1584-468X
Nature Immunology 25 (2): 282-293. February 2024

Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Cappel, C., Cremer, N., Hoffmann, P., Koudelka, T. ORCID: https://orcid.org/0009-0008-2895-6051, Tholey, A., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Damme, M. ORCID: https://orcid.org/0000-0002-9699-9351
Nucleic Acids Research 52 (1): 370-384. 11 January 2024

Topological reaction coordinate captures the folding transition state ensemble in a pierced lasso protein.
Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036 and Haglund, E. ORCID: https://orcid.org/0000-0002-6629-2793
Journal of Physical Chemistry B 128 (1): 117-124. 11 January 2024

2023

Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Cauchy, P. ORCID: https://orcid.org/0000-0002-0659-0799, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Giefing, M., Fornes, O. ORCID: https://orcid.org/0000-0002-5969-3054, Vankadari, N. ORCID: https://orcid.org/0000-0001-9363-080X, Assi, S.A., Costanza, M. ORCID: https://orcid.org/0000-0002-8959-1083, Weniger, M.A., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Anagnostopoulos, I. ORCID: https://orcid.org/0000-0002-5043-6043, Bukur, T., Casarotto, M.G. ORCID: https://orcid.org/0000-0002-0571-7671, Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Edginton-White, B., Gebhardt, J.C.M. ORCID: https://orcid.org/0000-0003-1900-600X, Grau, M., Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Hansmann, M.L., Hartmann, S. ORCID: https://orcid.org/0000-0003-3424-1091, Huber, L., Kärgel, E., Lusatis, S., Noerenberg, D., Obier, N., Pannicke, U. ORCID: https://orcid.org/0000-0002-0929-1794, Fischer, A. ORCID: https://orcid.org/0000-0002-7145-2544, Reisser, A., Rosenwald, A., Schwarz, K. ORCID: https://orcid.org/0000-0003-3178-5990, Sundararaj, S., Weilemann, A. ORCID: https://orcid.org/0009-0001-1340-6486, Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Xu, W., Lenz, G. ORCID: https://orcid.org/0000-0002-4728-1693, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Wasserman, W.W. ORCID: https://orcid.org/0000-0001-6098-6412, Cockerill, P.N. ORCID: https://orcid.org/0000-0002-4410-8174, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Siebert, R., Küppers, R., Grosschedl, R. ORCID: https://orcid.org/0000-0002-0058-1250, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Bonifer, C. ORCID: https://orcid.org/0000-0002-4267-0825 and Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413
Nature Communications 14 (1): 6947. 7 November 2023

MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
Abualrous, E.T. ORCID: https://orcid.org/0000-0001-9582-9089, Stolzenberg, S., Sticht, J. ORCID: https://orcid.org/0000-0002-4307-4726, Wieczorek, M., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Günther, M., Dähn, S., Boesen, B.B., Calvo, M.M. ORCID: https://orcid.org/0009-0008-9179-127X, Biese, C., Kuppler, F., Medina-García, Á., Álvaro-Benito, M. ORCID: https://orcid.org/0000-0002-6019-3567, Höfer, T. ORCID: https://orcid.org/0000-0003-3560-8780, Noé, F. ORCID: https://orcid.org/0000-0003-4169-9324 and Freund, C. ORCID: https://orcid.org/0000-0001-7416-8226
Nature Chemical Biology 19 (10): 1196-1204. October 2023

A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Fornes, O., Jia, A., Kuehn, H.S., Min, Q., Pannicke, U., Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Thouenon, R., Yu, Z., de Los Angeles Astbury, M., Biggs, C.M., Galicchio, M., Garcia-Campos, J.A., Gismondi, S., Gonzalez Villarreal, G., Hildebrand, K.J., Hönig, M., Hou, J., Moshous, D., Pittaluga, S., Qian, X., Rozmus, J., Schulz, A.S., Staines-Boone, A.T., Sun, B., Sun, J., Uwe, S., Venegas-Montoya, E., Wang, W., Wang, X., Ying, W., Zhai, X., Zhou, Q., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, André, I., Barth, T.F.E., Baumann, B., Brüstle, A., Burgio, G., Bustamante, J.C., Casanova, J.L., Casarotto, M.G., Cavazzana, M., Chentout, L., Cockburn, I.A., Costanza, M. ORCID: https://orcid.org/0000-0002-8959-1083, Cui, C., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Del Bel, K.L., Eibel, H., Feng, X., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Gebhardt, J.C.M., Götz, A., Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Hoareau, B., Hughes, T.R., Jacobsen, E.M., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Jolma, A., Lagresle-Peyrou, C., Lai, N., Li, Y., Lin, S., Lu, H.Y., Lugo-Reyes, S.O., Meng, X., Möller, P., Moreno-Corona, N., Niemela, J.E., Novakovsky, G., Perez-Caraballo, J.J., Picard, C., Poggi, L., Puig-Lombardi, M.E., Randall, K.L., Reisser, A., Schmitt, Y., Seneviratne, S., Sharma, M., Stoddard, J., Sundararaj, S., Sutton, H., Tran, L.Q., Wang, Y., Wasserman, W.W., Wen, Z., Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Xiong, E., Yang, A.W.H., Yu, M., Zhang, L., Zhang, H., Zhao, Q., Zhen, X., Enders, A., Kracker, S., Martinez-Barricarte, R., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Rosenzweig, S.D., Schwarz, K., Turvey, S.E. and Wang, J.Y.
Science Immunology 8 (79): eade7953. January 2023

Development of selective inhibitors of phosphatidylinositol 3-kinase C2α.
Lo, W.T., Belabed, H., Kücükdisli, M., Metag, J., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Prokofeva, P., Ohashi, Y. ORCID: https://orcid.org/0000-0002-2288-130X, Horatscheck, A. ORCID: https://orcid.org/0000-0001-6485-6391, Cirillo, D. ORCID: https://orcid.org/0000-0001-5133-0702, Krauss, M., Schmied, C. ORCID: https://orcid.org/0000-0003-2058-1124, Neuenschwander, M. ORCID: https://orcid.org/0000-0002-3114-7975, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Médard, G. ORCID: https://orcid.org/0000-0002-4782-4029, Kuster, Be. ORCID: https://orcid.org/0000-0002-9094-1677, Perisic, O., Williams, R.L. ORCID: https://orcid.org/0000-0001-7754-4207, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Payrastre, B. ORCID: https://orcid.org/0000-0002-8693-0190, Severin, S., Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330 and Haucke, V. ORCID: https://orcid.org/0000-0003-3119-6993
Nature Chemical Biology 19 (1): 18-27. January 2023

2022

Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.
Melo, A.A., Sprink, T. ORCID: https://orcid.org/0000-0002-0760-6828, Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036, Vázquez-Sarandeses, E., van Hoorn, C. ORCID: https://orcid.org/0000-0002-1319-847X, Mohd, S., Loerke, J. ORCID: https://orcid.org/0000-0002-3424-8536, Spahn, C.M.T. and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
Nature Communications 13 (1): 7641. 10 December 2022

Structural insights into crista junction formation by the Mic60-Mic19 complex.
Bock-Bierbaum, T. ORCID: https://orcid.org/0000-0003-0843-2716, Funck, K., Wollweber, F., Lisicki, E. ORCID: https://orcid.org/0000-0001-5012-8377, von der Malsburg, K., von der Malsburg, A., Laborenz, J., Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036, Hessenberger, M. ORCID: https://orcid.org/0000-0003-3021-1100, Jungbluth, S., Bernert, C., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Riedel, D., Lilie, H., Jakobs, S., van der Laan, M. and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
Science Advances 8 (35): eabo4946. 2 September 2022

GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao, Y. ORCID: https://orcid.org/0000-0002-8890-2409, Du Jiang, P. ORCID: https://orcid.org/0000-0002-9900-8277, Chao, B.N. ORCID: https://orcid.org/0000-0002-0355-2332, Cagdas, D. ORCID: https://orcid.org/0000-0003-2213-4627, Kubo, S. ORCID: https://orcid.org/0000-0001-9693-9263, Balasubramaniyam, A. ORCID: https://orcid.org/0000-0003-4168-8617, Zhang, Y. ORCID: https://orcid.org/0000-0002-6904-0372, Shadur, B. ORCID: https://orcid.org/0000-0003-0245-894X, NaserEddin, A. ORCID: https://orcid.org/0000-0001-6995-3262, Folio, L.R., Schwarz, B. ORCID: https://orcid.org/0000-0002-5894-953X, Bohrnsen, E. ORCID: https://orcid.org/0000-0003-4327-5242, Zheng, L. ORCID: https://orcid.org/0000-0002-8838-8665, Lynberg, M. ORCID: https://orcid.org/0000-0003-1371-3002, Gottlieb, S. ORCID: https://orcid.org/0000-0003-0550-4761, Leney-Greene, M.A. ORCID: https://orcid.org/0000-0002-3259-1728, Park, A.Y. ORCID: https://orcid.org/0000-0002-0130-1521, Tezcan, I. ORCID: https://orcid.org/0000-0001-7257-4554, Akdogan, A., Gocmen, R. ORCID: https://orcid.org/0000-0002-0223-9336, Onder, S. ORCID: https://orcid.org/0000-0002-5523-0669, Rosenberg, A., Soilleux, E.J. ORCID: https://orcid.org/0000-0002-4032-7249, Johnson, E. ORCID: https://orcid.org/0000-0001-8435-9472, Jackson, P.K. ORCID: https://orcid.org/0000-0002-1742-2539, Demeter, J., Chauvin, S.D. ORCID: https://orcid.org/0000-0003-0232-751X, Paul, F. ORCID: https://orcid.org/0000-0001-5181-3122, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Bulut, H. ORCID: https://orcid.org/0000-0003-0262-6296, Clatworthy, M.R. ORCID: https://orcid.org/0000-0002-3340-9828, Tuong, Z.K. ORCID: https://orcid.org/0000-0002-6735-6808, Zhang, H., Stewart, B.J. ORCID: https://orcid.org/0000-0003-4522-0085, Bosio, C.M. ORCID: https://orcid.org/0000-0002-7332-9611, Stepensky, P. ORCID: https://orcid.org/0000-0002-4923-3660, Clare, S. ORCID: https://orcid.org/0000-0001-9368-6037, Ganesan, S. ORCID: https://orcid.org/0000-0003-1132-2016, Pascall, J.C. ORCID: https://orcid.org/0000-0002-9506-1441, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Butcher, G.W. ORCID: https://orcid.org/0000-0002-3423-7124, McMichael, A.J. ORCID: https://orcid.org/0000-0002-9101-7478, Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Lenardo, M.J. ORCID: https://orcid.org/0000-0003-1584-468X
Journal of Experimental Medicine 219 (6): e20201405. 6 June 2022

Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
Marino, S.F. ORCID: https://orcid.org/0000-0001-5696-9679, Jerke, U., Rolle, S. ORCID: https://orcid.org/0000-0002-1909-687X, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Kettritz, R. ORCID: https://orcid.org/0000-0001-5821-6718
Journal of Biological Chemistry 298 (3): 101598. March 2022

Structural basis of phosphatidylinositol 3-kinase C2α function.
Lo, W.T. ORCID: https://orcid.org/0000-0001-7904-6834, Zhang, Y., Vadas, O. ORCID: https://orcid.org/0000-0003-3511-6479, Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Gulluni, F., De Santis, M.C. ORCID: https://orcid.org/0000-0003-2785-0665, Zagar, A.V., Stephanowitz, H., Hirsch, E., Liu, F. ORCID: https://orcid.org/0000-0002-2358-549X, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Haucke, V. ORCID: https://orcid.org/0000-0003-3119-6993
Nature Structural & Molecular Biology 29 (3): 218-228. March 2022

SPFH protein cage - one ring to rule them all.
Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352
Cell Research 32 (2): 117-118. February 2022

SMOG 2 and OpenSMOG: extending the limits of structure-based models.
de Oliveira, A.B., Contessoto, V.G., Hassan, A., Byju, S., Wang, A., Wang, Y., Dodero-Rojas, E., Mohanty, U., Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036, Onuchic, J.N. and Whitford, P.C. ORCID: https://orcid.org/0000-0001-7104-2265
Protein Science 31 (1): 158-172. January 2022

2021

Lysine acetylation regulates the interaction between proteins and membranes.
Okada, A.K. ORCID: https://orcid.org/0000-0001-8338-9557, Teranishi, K., Ambroso, M.R., Isas, J.M., Vazquez-Sarandeses, E., Lee, J.Y. ORCID: https://orcid.org/0000-0001-6616-5594, Melo, A.A., Pandey, P., Merken, D., Berndt, L., Lammers, M., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Chang, K., Haworth, I.S. ORCID: https://orcid.org/0000-0002-3873-0899 and Langen, R.
Nature Communications 12 (1): 6466. 9 November 2021

A simple pressure-assisted method for MicroED specimen preparation.
Zhao, J. ORCID: https://orcid.org/0000-0001-8444-6883, Xu, H. ORCID: https://orcid.org/0000-0002-8271-3906, Lebrette, H., Carroni, M. ORCID: https://orcid.org/0000-0002-7697-6427, Taberman, H. ORCID: https://orcid.org/0000-0001-7595-4608, Högbom, M. and Zou, X. ORCID: https://orcid.org/0000-0001-6748-6656
Nature Communications 12 (1): 5036. 19 August 2021

Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor.
Ganichkin, O.M., Vancraenenbroeck, R. ORCID: https://orcid.org/0000-0003-2685-2749, Rosenblum, G., Hofmann, H. ORCID: https://orcid.org/0000-0003-1669-3158, Mikhailov, A.S. ORCID: https://orcid.org/0000-0002-2416-8401, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036
Proceedings of the National Academy of Sciences of the United States of America 118 (28): e2101144118. 13 July 2021

Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily.
Liu, J., Tassinari, M., Souza, D.P., Naskar, S., Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036, Bohuszewicz, O., Buck, M., Williams, T.A., Baum, B. and Low, H.H.
Cell 184 (14): 3660-3673. 8 July 2021

The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells.
Wilhelmi, Ilka, Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Gimber, N. ORCID: https://orcid.org/0000-0001-9456-3063, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Arumughan, A., Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630, Laeger, T. ORCID: https://orcid.org/0000-0002-2763-0497, Schmoranzer, J., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Schümann, A. ORCID: https://orcid.org/0000-0002-4113-4377
Molecular Metabolism 45 : 101151. March 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
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Autophagy 17 (1): 1-382. 8 February 2021