Browse by Journal Title

2024

Epigenetic regulatory layers in the 3D nucleus.
Willemin, A., Szabo, D. and Pombo, A.
Molecular Cell 84 (3): 415-428. 1 February 2024

Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.
Hofman, D.A., Ruiz-Orera, J., Yannuzzi, I., Murugesan, R., Brown, A., Clauser, K.R., Condurat, A.L., van Dinter, J.T., Engels, S.A.G., Goodale, A., van der Lugt, J., Abid, T., Wang, L., Zhou, K.N., Vogelzang, J., Ligon, K.L., Phoenix, T.N., Roth, J.A., Root, D.E, Hubner, N., Golub, T.R., Bandopadhayay, P., van Heesch, S. and Prensner, J.R.
Molecular Cell 84 (2): 261-276. 18 January 2024

2023

mRNA stability and m(6)A are major determinants of subcellular mRNA localization in neurons.
Loedige, I., Baranovskii, A., Mendonsa, S., Dantsuji, S., Popitsch, N., Breimann, L., Zerna, N., Cherepanov, V., Milek, M., Ameres, S. and Chekulaeva, M.
Molecular Cell 83 (15): 2709-2725. 3 August 2023

Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames.
Sandmann, C.L., Schulz, J.F., Ruiz-Orera, J., Kirchner, M., Ziehm, M., Adami, E., Marczenke, M., Christ, A., Liebe, N., Greiner, J., Schoenenberger, A., Mücke, M.B., Liang, N., Moritz, R.L., Sun, Z., Deutsch, E.W., Gotthardt, M., Mudge, J.M., Prensner, J.R., Willnow, T.E., Mertins, P., van Heesch, S. and Hubner, N.
Molecular Cell 83 (6): 994-1011.e18. 16 March 2023

2022

SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA.
Maharana, S., Kretschmer, S., Hunger, S., Yan, X., Kuster, D., Traikov, S., Zillinger, T., Gentzel, M., Elangovan, S., Dasgupta, P., Chappidi, N., Lucas, N., Maser, K.I., Maatz, H., Rapp, A., Marchand, V., Chang, Y.T., Motorin, Y., Hubner, N., Hartmann, G., Hyman, A.A., Alberti, S. and Lee-Kirsch, M.A.
Molecular Cell 82 (19): 3712-3728.e10. 6 October 2022

The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition.
Zonderland, G., Vanzo, R., Amitash, S., Martín-Doncel, E., Coscia, F., Mund, A., Lerdrup, M., Benada, J., Boos, D. and Toledo, L.
Molecular Cell 82 (18): 3350-3365. 15 September 2022

A high-resolution map of human RNA translation.
Chothani, S.P., Adami, E., Widjaja, A.A., Langley, S.R., Viswanathan, S., Pua, C.J., Zhihao, N.T., Harmston, N., D'Agostino, G., Whiffin, N., Mao, W., Ouyang, J.F., Lim, W.W., Lim, S., Lee, C.Q.E., Grubman, A., Chen, J., Kovalik, J.P., Tryggvason, K., Polo, J.M., Ho, L., Cook, S.A., Rackham, O.J.L. and Schafer, S.
Molecular Cell 82 (15): 2885-2899.e8. 4 August 2022

Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20.
Vieira e Vieira, C.H., Dauksaite, V., Sporbert, A., Gotthardt, M. and Selbach, M.
Molecular Cell 82 (11): 2069-2083. 2 June 2022

ATACing single cells with phages.
Maschmeyer, P. and Haas, S.
Molecular Cell 82 (2): 234-236. 20 January 2022

Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus.
Gjaltema, R.A.F., Schwämmle, T., Kautz, P., Robson, M., Schöpflin, R., Ravid Lustig, L., Brandenburg, L., Dunkel, I., Vechiatto, C., Ntini, E., Mutzel, V., Schmiedel, V., Marsico, A., Mundlos, S. and Schulz, E.G.
Molecular Cell 82 (1): 190-208.e17. 6 January 2022

2021

The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
Heider, M., Eichner, R., Stroh, J., Morath, V., Kuisl, A., Zecha, J., Lawatscheck, J., Baek, K., Garz, A.K., Rudelius, M., Deuschle, F.C., Keller, U., Lemeer, S., Verbeek, M., Götze, K.S., Skerra, A., Weber, W.A., Buchner, J., Schulman, B.A., Kuster, B., Fernández-Sáiz, V. and Bassermann, F.
Molecular Cell 81 (6): 1170-1186. 18 March 2021

Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Nikolay, R., Hilal, T., Schmidt, S., Qin, B., Schwefel, D., Vieira-Vieira, C.H., Mielke, T., Bürger, J., Loerke, J., Amikura, K., Flügel, T., Ueda, T., Selbach, M., Deuerling, E. and Spahn, C.M.T.
Molecular Cell 81 (6): 1200-1215. 18 March 2021

Protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit.
Kraushar, M.L., Krupp, F., Harnett, D., Turko, P., Ambrozkiewicz, M.C., Sprink, T., Imami, K., Günnigmann, M., Zinnall, U., Vieira-Vieira, C.H., Schaub, T., Münster-Wandowski, A., Bürger, J., Borisova, E., Yamamoto, H., Rasin, M.R., Ohler, U., Beule, D., Mielke, T., Tarabykin, V., Landthaler, M., Kramer, G., Vida, I., Selbach, M. and Spahn, C.M.T.
Molecular Cell 81 (2): 304-322. 21 January 2021

2020

Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription.
Cossa, G., Roeschert, I., Prinz, F., Baluapuri, A., Silveira Vidal, R., Schülein-Völk, C., Chang, Y.C., Ade, C.P., Mastrobuoni, G., Girard, C., Kumar, A., Wortmann, L., Walz, S., Lührmann, R., Kempa, S., Kuster, B., Wolf, E., Mumberg, D. and Eilers, M.
Molecular Cell 77 (6): 1322-1339. 19 March 2020

A conserved noncoding locus regulates random monoallelic Xist expression across a topological boundary.
Galupa, R., Nora, E.P., Worsley-Hunt, R., Picard, C., Gard, C., van Bemmel, J.G., Servant, N., Zhan, Y., El Marjou, F., Johanneau, C., Diabangouaya, P., Le Saux, A., Lameiras, S., Pipoli da Fonseca, J., Loos, F., Gribnau, J., Baulande, S., Ohler, U., Giorgetti, L. and Heard, E.
Molecular Cell 77 (2): 352-367. 16 January 2020

2019

Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence.
Zhang, H., Alsaleh, G., Feltham, J., Sun, Y., Napolitano, G., Riffelmacher, T., Charles, P., Frau, L., Hublitz, P., Yu, Z., Mohammed, S., Ballabio, A., Balabanov, S., Mellor, J. and Simon, A.K.
Molecular Cell 76 (1): 110-125. 3 October 2019

Conserved pseudoknots in lncRNA MEG3 are essential for stimulation of the p53 pathway.
Uroda, T., Anastasakou, E., Rossi, A., Teulon, J.M., Pellequer, J.L., Annibale, P., Pessey, O., Inga, A., Chillón, I. and Marcia, M.
Molecular Cell 75 (5): 982-995. 5 September 2019

Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis.
Wild, P., Susperregui, A., Piazza, I., Dörig, C., Oke, A., Arter, M., Yamaguchi, M., Hilditch, A.T., Vuina, K., Chan, K.C., Gromova, T., Haber, J.E., Fung, J.C., Picotti, P. and Matos, J.
Molecular Cell 75 (4): 859-874. 22 August 2019

Regulatory landscaping: how enhancer-promoter communication is sculpted in 3D.
Robson, M.I., Ringel, A.R. and Mundlos, S.
Molecular Cell 74 (6): 1110-1122. 20 June 2019

FIP200 claw domain binding to p62 promotes autophagosome formation at ubiquitin condensates.
Turco, E., Witt, M., Abert, C., Bock-Bierbaum, T., Su, M.Y., Trapannone, R., Sztacho, M., Danieli, A., Shi, X., Zaffagnini, G., Gamper, A., Schuschnig, M., Fracchiolla, D., Bernklau, D., Romanov, J., Hartl, M., Hurley, J.H., Daumke, O. and Martens, S.
Molecular Cell 74 (2): 330-346. 18 April 2019

R-loops enhance polycomb repression at a subset of developmental regulator genes.
Skourti-Stathaki, K., Torlai Triglia, E., Warburton, M., Voigt, P., Bird, A. and Pombo, A.
Molecular Cell 73 (5): 930-945. 7 March 2019

Small and large ribosomal subunit deficiencies lead to distinct gene expression signatures that reflect cellular growth rate.
Cheng, Z., Mugler, C.F., Keskin, A., Hodapp, S., Chan, L.Y.L., Weis, K., Mertins, P., Regev, A., Jovanovic, M. and Brar, G.A.
Molecular Cell 73 (1): 36-47. 3 January 2019

2018

The chromatin reader ZMYND8 regulates Igh enhancers to promote immunoglobulin class switch recombination.
Delgado-Benito, V., Rosen, D.B., Wang, Q., Gazumyan, A., Pai, J.A., Oliveira, T.Y., Sundaravinayagam, D., Zhang, W., Andreani, M., Keller, L., Kieffer-Kwon, K.R., Pękowska, A., Jung, S., Driesner, M., Subbotin, R.I., Casellas, R., Chait, B.T., Nussenzweig, M.C. and Di Virgilio, M.
Molecular Cell 72 (4): 636-649. 15 November 2018

Exon junction complexes suppress spurious splice sites to safeguard transcriptome integrity.
Boehm, V., Britto-Borges, T., Steckelberg, A.L., Singh, K.K., Gerbracht, J.V., Gueney, E., Blazquez, L., Altmüller, J., Dieterich, C. and Gehring, N.H.
Molecular Cell 72 (3): 482-495. 1 November 2018

Phosphorylation of the ribosomal protein RPL12/uL11 affects translation during mitosis.
Imami, K., Milek, M., Bogdanow, B., Yasuda, T., Kastelic, N., Zauber, H., Ishihama, Y., Landthaler, M. and Selbach, M.
Molecular Cell 72 (1): 84-98. 4 October 2018

mHTT seeding activity: a marker of disease progression and neurotoxicity in models of Huntington's disease.
Ast, A., Buntru, A., Schindler, F., Hasenkopf, R., Schulz, A., Brusendorf, L., Klockmeier, K., Grelle, G., McMahon, B., Niederlechner, H., Jansen, I., Diez, L., Edel, J., Boeddrich, A., Franklin, S.A., Baldo, B., Schnoegl, S., Kunz, S., Purfürst, B., Gaertner, A., Kampinga, H.H., Morton, A.J., Petersén, Å., Kirstein, J., Bates, G.P. and Wanker, E.E.
Molecular Cell 71 (5): 675-688. 6 September 2018

Bacterial RNA biology on a genome scale.
Hör, J., Gorski, S.A. and Vogel, J.
Molecular Cell 70 (5): 785-799. 7 June 2018

RNA helicase DDX1 converts RNA G-quadruplex structures into R-loops to promote IgH class switch recombination.
Ribeiro de Almeida, C., Dhir, S., Dhir, A., Moghaddam, A.E., Sattentau, Q., Meinhart, A. and Proudfoot, N.J.
Molecular Cell 70 (4): 650-662. 17 May 2018

HMGB2 loss upon senescence entry disrupts genomic organization and induces CTCF clustering across cell types.
Zirkel, A., Nikolic, M., Sofiadis, K., Mallm, J.P., Brackley, C.A., Gothe, H., Drechsel, O., Becker, C., Altmüller, J., Josipovic, N., Georgomanolis, T., Brant, L., Franzen, J., Koker, M., Gusmao, E.G., Costa, I.G., Ullrich, R.T., Wagner, W., Roukos, V., Nürnberg, P., Marenduzzo, D., Rippe, K. and Papantonis, A.
Molecular Cell 70 (4): 730-744.e6. 17 May 2018

2017

Circ-ZNF609 is a circular RNA that can be translated and functions in myogenesis.
Legnini, I., Di Timoteo, G., Rossi, F., Morlando, M., Briganti, F., Sthandier, O., Fatica, A., Santini, T., Andronache, A., Wade, M., Laneve, P., Rajewsky, N. and Bozzoni, I.
Molecular Cell 66 (1): 22-37.e9. 6 April 2017

Translation of circRNAs.
Pamudurti, N.R., Bartok, O., Jens, M., Ashwal-Fluss, R., Stottmeister, C., Ruhe, L., Hanan, M., Wyler, E., Perez-Hernandez, D., Ramberger, E., Shenzis, S., Samson, M., Dittmar, G., Landthaler, M., Chekulaeva, M., Rajewsky, N. and Kadener, S.
Molecular Cell 66 (1): 9-21. 6 April 2017

Identification of an RNA polymerase III regulator linked to disease-associated protein aggregation.
Sin, O., de Jong, T., Mata-Cabana, A., Kudron, M., Zaini, M.A., Aprile, F.A., Seinstra, R.I., Stroo, E., Prins, R.W., Martineau, C.N., Wang, H.H., Hogewerf, Wytse, Steinhof, A., Wanker, E.E., Vendruscolo, M., Calkhoven, C.F., Reinke, V., Guryev, V. and Nollen, E.A.A.
Molecular Cell 65 (6): 1096-1108. 16 March 2017

Deciphering the ubiquitin code.
Dittmar, G. and Selbach, M.
Molecular Cell 65 (5): 779-780. 2 March 2017

A finer print than TADs: PRC1-mediated domains.
Torlai Triglia, E., Rito, Tiago and Pombo, A.
Molecular Cell 65 (3): 373-375. 2 February 2017

2016

Stefan Jentsch (1955-2016) Obituary.
Sommer, T., Hoppe, T. and Rape, M.
Cell Press. 15 December 2016

Eyes on translation.
Chekulaeva, M. and Landthaler, M.
Molecular Cell 63 (6): 918-925. 15 September 2016

Mapping the landscape of a eukaryotic degronome.
Geffen, Y., Appleboim, A., Gardner, R.G., Friedman, N., Sadeh, R. and Ravid, T.
Molecular Cell 63 (6): 1055-1065. 15 September 2016

Sequential poly-ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase.
Weber, A., Cohen, I., Popp, O., Dittmar, G., Reiss, Y., Sommer, T., Ravid, T. and Jarosch, E.
Molecular Cell 63 (5): 827-839. 1 September 2016

OCT4 acts as an integrator of pluripotency and signal-induced differentiation.
Simandi, Z., Horvath, A., Wright, L.C., Cuaranta-Monroy, I., De Luca, I., Karolyi, K., Sauer, S., Deleuze, J.F., Gudas, L.J., Cowley, S.M. and Nagy, L.
Molecular Cell 63 (4): 647-661. 18 August 2016

The Lupus autoantigen La prevents Mis-channeling of tRNA fragments into the human microRNA pathway.
Hasler, D., Lehmann, G., Murakawa, Y., Klironomos, F., Jakob, L., Grässer, F.A., Rajewsky, N., Landthaler, M. and Meister, G.
Molecular Cell 63 (1): 110-124. 7 July 2016

Tissue-specific gene repositioning by muscle nuclear membrane proteins enhances repression of critical developmental genes during myogenesis.
Robson, M.I., de Las Heras, J.I., Czapiewski, R., Lê Thành, P., Booth, D.G., Kelly, D.A., Webb, S., Kerr, A.R.W. and Schirmer, E.C.
Molecular Cell 62 (6): 834-847. 16 June 2016

The CUE domain of Cue1 aligns growing ubiquitin chains with Ubc7 for rapid elongation.
von Delbrück, M., Kniss, A., Rogov, V.V., Pluska, L., Bagola, K., Löhr, F., Güntert, P., Sommer, T. and Dötsch, V.
Molecular Cell 62 (6): 918-928. 16 June 2016

2015

A regression-based analysis of ribosome-profiling data reveals a conserved complexity to mammalian translation.
Fields, A.P., Rodriguez, E.H., Jovanovic, M., Stern-Ginossar, N., Haas, B.J., Mertins, P., Raychowdhury, R., Hacohen, N., Carr, S.A., Ingolia, N.T., Regev, A. and Weissman, J.S.
Molecular Cell 60 (5): 816-827. 3 December 2015

Perspectives on unidirectional versus divergent transcription.
Duttke, S.H.C., Lacadie, S.A., Ibrahim, M.M., Glass, C.K., Corcoran, D.L., Benner, C., Heinz, S., Kadonaga, J.T. and Ohler, U.
Molecular Cell 60 (3): 348-349. 5 November 2015

Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed.
Rybak-Wolf, A., Stottmeister, C., Glažar, P., Jens, M., Pino, N., Giusti, S., Hanan, M., Behm, M., Bartok, O., Ashwal-Fluss, R., Herzog, M., Schreyer, L., Papavasileiou, P., Ivanov, A., Öhman, M., Refojo, D., Kadener, S. and Rajewsky, N.
Molecular Cell 58 (5): 870-885. 4 June 2015

Single-cell transcriptomics enters the age of mass production.
Junker, J.P. and van Oudenaarden, A.
Molecular Cell 58 (4): 563-564. 21 May 2015

High-resolution chromatin dynamics during a yeast stress response.
Weiner, A., Hsieh, T.H.S., Appleboim, A., Chen, H.V., Rahat, A., Amit, I., Rando, O.J. and Friedman, N.
Molecular Cell 58 (2): 371-386. 16 April 2015

Human promoters are intrinsically directional.
Duttke, S.H.C., Lacadie, S.A., Ibrahim, M.M., Glass, C.K., Corcoran, D.L., Benner, C., Heinz, S., Kadonaga, J.T. and Ohler, U.
Molecular Cell 57 (4): 674-684. 19 February 2015

2014

circRNA biogenesis competes with pre-mRNA splicing.
Ashwal-Fluss, R., Meyer, M., Pamudurti, N.R., Ivanov, A., Bartok, O., Hanan, M., Evantal, N., Memczak, S., Rajewsky, N. and Kadener, S.
Molecular Cell 56 (1): 55-66. 2 October 2014

Unambiguous identification of miRNA:target site interactions by different types of ligation reactions.
Grosswendt, S., Filipchyk, A., Manzano, M., Klironomos, F., Schilling, M., Herzog, M., Gottwein, E. and Rajewsky, N.
Molecular Cell 54 (6): 1042-1054. 19 June 2014

MOV10 is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.
Gregersen, L.H., Schueler, M., Munschauer, M., Mastrobuoni, G., Chen, W., Kempa, S., Dieterich, C. and Landthaler, M.
Molecular Cell 54 (4): 573-585. 22 May 2014

2013

The ZFP-1(AF10)/DOT-1 complex opposes H2B ubiquitination to reduce Pol II transcription.
Cecere, G., Hoersch, S., Jensen, M.B., Dixit, S. and Grishok, A.
Molecular Cell 50 (6): 894-907. 27 June 2013

Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Bagola, K., von Delbrück, M., Dittmar, G., Scheffner, M., Ziv, I., Glickman, M.H., Ciechanover, A. and Sommer, T.
Molecular Cell 50 (4): 528-539. 23 May 2013

The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO.
Mueller-Rischart, A.K., Pilsl, A., Beaudette, P., Patra, M., Hadian, K., Funke, M., Peis, R., Deinlein, A., Schweimer, C., Kuhn, P.H., Lichtenthaler, S.F., Motori, E., Hrelia, S., Wurst, W, Truembach, D., Langer, T., Krappmann, D., Dittmar, G., Tatzelt, J. and Winklhofer, K.F.
Molecular Cell 49 (5): 908-921. 7 March 2013

Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.
Staber, P.B., Zhang, P., Ye, M., Welner, R.S., Nombela-Arrieta, C., Bach, C., Kerenyi, M., Bartholdy, B.A., Zhang, H., Alberich-Jorda, M., Lee, S., Yang, H., Ng, F., Zhang, J., Leddin, M., Silberstein, L.E., Hoefler, G., Orkin, S.H., Goettgens, B., Rosenbauer, F., Huang, G. and Tenen, D.G.
Molecular Cell 49 (5): 934-946. 7 March 2013

Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathways.
Anton, F., Dittmar, G., Langer, T. and Escobar-Henriques, M.
Molecular Cell 49 (3): 487-498. 7 February 2013

Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes.
Uhlenhaut, N.H., Barish, G.D., Yu, R.T., Downes, M., Karunasiri, M., Liddle, C., Schwalie, P., Hübner, N. and Evans, R.M.
Molecular Cell 49 (1): 158-171. 10 January 2013

2012

The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation.
Shabek, N., Herman-Bachinsky, Y., Buchsbaum, S., Lewinson, O., Haj-Yahya, M., Hejjaoui, M., Lashuel, H.A., Sommer, T., Brik, A. and Ciechanover, A.
Molecular Cell 48 (1): 87-97. 12 October 2012

Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase.
Karanam, K., Kafri, R., Loewer, A. and Lahav, G.
Molecular Cell 47 (2): 320-329. 27 July 2012

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz, A.G., Munschauer, M., Schwanhaeusser, B., Vasile, A., Murakawa, Y., Schueler, M., Youngs, N., Penfold-Brown, D., Drew, K., Milek, M., Wyler, E., Bonneau, R., Selbach, M., Dieterich, C. and Landthaler, M.
Molecular Cell 46 (5): 674-690. 8 June 2012

When noisy neighbors are a blessing: analysis of gene expression noise identifies coregulated genes.
Junker, J.P. and van Oudenaarden, A.
Molecular Cell 45 (4): 437-438. 24 February 2012

2011

In vivo and transcriptome-wide identification of RNA binding protein target sites.
Jungkamp, A.C., Stoeckius, M., Mecenas, D., Gruen, D., Mastrobuoni, G., Kempa, S. and Rajewsky, N.
Molecular Cell 44 (5): 828-840. 9 December 2011

Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR.
Lebedeva, S., Jens, M., Theil, K., Schwanhaeusser, B., Selbach, M., Landthaler, M. and Rajewsky, N.
Molecular Cell 43 (3): 340-352. 5 August 2011

Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.
Mukherjee, N., Corcoran, D.L., Nusbaum, J.D., Reid, D.W., Georgiev, S., Hafner, M., Ascano, M., Tuschl, T., Ohler, U. and Keene, J.D.
Molecular Cell 43 (3): 327-339. 5 August 2011

Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.
Bothmer, A., Robbiani, D.F., Di Virgilio, M., Bunting, S.F., Klein, I.A., Feldhahn, N., Barlow, J., Chen, H.T., Bosque, D., Callen, E., Nussenzweig, A. and Nussenzweig, M.C.
Molecular Cell 42 (3): 319-329. 6 May 2011

2010

Global analysis of nascent RNA reveals transcriptional pausing in terminal exons.
Carrillo Oesterreich, F., Preibisch, S. and Neugebauer, K.M.
Molecular Cell 40 (4): 571-581. 24 November 2010

Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.
Buchberger, A., Bukau, B. and Sommer, T.
Molecular Cell 40 (2): 238-252. 22 October 2010

A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
Hinz, M., Stilmann, M., Coel Arslan, S., Khanna, K.K., Dittmar, G. and Scheidereit, C.
Molecular Cell 40 (1): 63-74. 8 October 2010

Chaperones get RISC loaded.
Landthaler, M.
Molecular Cell 39 (2): 161-162. 30 July 2010

Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2.
Kanhere, A., Viiri, K., Araujo, C.C., Rasaiyaah, J., Bouwman, R.D., Whyte, W.A., Pereira, C.F., Brookes, E., Walker, K., Bell, G.W., Pombo, A., Fisher, A.G., Young, R.A. and Jenner, R.G.
Molecular Cell 38 (5): 675-688. 11 June 2010

2009

Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
Horn, S.C., Hanna, J., Hirsch, C., Volkwein, C., Schütz, A., Heinemann, U., Sommer, T. and Jarosch, E.
Molecular Cell 36 (5): 782-793. 11 December 2009

A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IκB kinase activation.
Stilmann, M., Hinz, M., Coel Arslan, S., Zimmer, A., Schreiber, V. and Scheidereit, C.
Molecular Cell 36 (3): 365-378. 13 November 2009

Ribosomal protein S7 is both a regulator and a substrate of MDM2.
Zhu, Y., Poyurovsky, M.V., Li, Y., Biderman, L., Stahl, J., Jacq, X. and Prives, C.
Molecular Cell 35 (3): 316-326. 14 August 2009

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.
Callen, E., Jankovic, M., Wong, N., Zha, S., Chen, H.T., Difilippantonio, S., Di Virgilio, M., Heidkamp, G., Alt, F.W., Nussenzweig, A. and Nussenzweig, M.
Molecular Cell 34 (3): 285-297. 15 May 2009

2008

A human snoRNA with microRNA-like functions.
Ender, C., Krek, A., Friedlaender, M.R., Beitzinger, M., Weinmann, L., Chen, W., Pfeffer, S., Rajewsky, N. and Meister, G.
Molecular Cell 32 (4): 519-528. 21 November 2008

Modulation of RNA polymerase assembly dynamics in transcriptional regulation.
Gorski, S.A., Snyder, S.K., John, S., Grummt, I. and Misteli, T.
Molecular Cell 30 (4): 486-497. 23 May 2008

Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage.
Batchelor, E., Mock, C.S., Bhan, I., Loewer, A. and Lahav, G.
Molecular Cell 30 (3): 277-289. 9 May 2008

2007

Balancing BMP signaling through integrated inputs into the Smad1 linker.
Sapkota, G., Alarcon, C., Spagnoli, F.M., Brivanlou, A.H. and Massague, J.
Molecular Cell 25 (3): 441-454. 9 February 2007

2006

A genome-wide analysis indicates that yeast pre-mRNA splicing is predominantly posttranscriptional.
Tardiff, D.F., Lacadie, S.A. and Rosbash, M.
Molecular Cell 24 (6): 917-929. 28 December 2006

Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.
Wegener, E., Oeckinghaus, A., Papadopoulou, N., Lavitas, L., Schmidt-Supprian, M., Ferch, U., Mak, T.W., Ruland, J., Heissmeyer, V. and Krappmann, D.
Molecular Cell 23 (1): 13-23. 7 July 2006

2005

Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast.
Lacadie, S.A. and Rosbash, M.
Molecular Cell 19 (1): 65-75. 1 July 2005

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.
Ding, Q., Xia, W., Liu, J.C., Yang, J.Y., Lee, D.F., Xia, J., Bartholomeusz, G., Li, Y., Pan, Y., Li, Z., Bargou, R.C., Qin, J., Lai, C.C., Tsai, F.J., Tsai, C.H. and Hung, M.C.
Molecular Cell 19 : 159-170. 1 January 2005

2004

The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF.
Philippar, U., Schratt, G., Dieterich, C., Mueller, J.M., Galgoczy, P., Engel, F.B., Keating, M.T., Gertler, F., Schuele, R., Vingron, M. and Nordheim, A.
Molecular Cell 16 (6): 867-880. 22 December 2004

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
Goehler, H., Lalowski, M., Stelzl, U., Waelter, S., Stroedicke, M., Worm, U., Droege, A., Lindenberg, K.S., Knoblich, M., Haenig, C., Herbst, M., Suopanki, J., Scherzinger, E., Abraham, C., Bauer, B., Hasenbank, R., Fritzsche, A., Ludewig, A.H., Buessow, K., Coleman, S.H., Gutekunst, C.A., Landwehrmeyer, B.G., Lehrach, H. and Wanker, E.E.
Molecular Cell 15 (6): 853-865. 24 September 2004

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.
Meister, G., Landthaler, M., Patkaniowska, A., Dorsett, Y., Teng, G. and Tuschl, T.
Molecular Cell 15 (2): 185-197. 23 July 2004

Ras induces mediator complex exchange on C/EBPβ.
Mo, X.M., Kowenz-Leutz, E., Xu, H. and Leutz, A.
Molecular Cell 13 (2): 241-250. 30 January 2004

A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
Bourbon, H.M., Aguilera, A., Ansari, A.Z., Asturias, F.J., Berk, A.J., Bjorklund, S., Blackwell, T.K., Borggrefe, T., Carey, M., Carlson, M., Conaway, J.W., Conaway, R.C., Emmons, S.W., Fondell, J.D., Freedman, L.P., Fukasawa, T., Gustafsson, C.M., Han, M., He, X., Herman, P.K., Hinnebusch, A.G., Holmberg, S., Holstege, F.C., Jaehning, J.A., Kim, Y.J., Kuras, L., Leutz, A., Lis, J.T., Meisterernest, M., Naar, A.M., Nasmyth, K., Parvin, J.D., Ptashne, M., Reinberg, D., Ronne, H., Sadowski, I., Sakurai, H., Sipiczki, M., Sternberg, P.W., Stillman, D.J., Strich, R., Struhl, K., Svejstrup, J.Q., Tuck, S., Winston, F., Roeder, R.G. and Kornberg, R.D.
Molecular Cell 14 (5): 553-557. 1 January 2004

Healing the wounds inflicted by Sleeping Beauty transposition by double-strand break repair in mammalian somatic cells.
Izsvak, Z., Stuewe, E.E., Fiedler, D., Katzer, A., Jeggo, P.A. and Ivics, Z.
Molecular Cell 13 (2): 279-290. 1 January 2004

Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation.
Meusser, B. and Sommer, T.
Molecular Cell 14 (2): 247-258. 1 January 2004

2002

DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters.
Sporbert, A., Gahl, A., Ankerhold, R., Leonhardt, H. and Cardoso, M.C.
Molecular Cell 10 (6): 1355-1365. December 2002

Phosphorylation by protein kinase CK2: A signaling switch for the caspase-inhibiting protein ARC.
Li, P.F., Li, J.C., Mueller, E.C., Otto, A., Dietz, R. and von Harsdorf, R.
Molecular Cell 10 (2): 247-258. August 2002

2000

The level of C/EBP protein is critical for cell migration during Drosophila oogenesis and is tightly controlled by regulated degradation.
Rorth, P., Szabo, K. and Texido, G.
Molecular Cell 6 : 23-30. 1 July 2000

1999

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src.
Wong, B.R., Besser, D., Kim, N., Arron, J.R., Vologodskaia, M., Hanafusa, H. and Choi, Y.
Molecular Cell 4 (6): 1041-1049. December 1999

A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes.
Kowenz-Leutz, E. and Leutz, A.
Molecular Cell 4 (5): 735-743. November 1999

1998

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates.
Sittler, A., Walter, S., Wedemeyer, N., Hasenbank, R., Scherzinger, E., Eickhoff, H., Bates, G.P., Lehrach, H. and Wanker, E.E.
Molecular Cell 2 (4): 427-436. October 1998

Identification of a tRNA-specific nuclear export receptor.
Kutay, U., Lipowsky, G., Izaurralde, E., Bischoff, F.R., Schwarzmaier, P., Hartmann, E. and Goerlich, D.
Molecular Cell 1 : 359-369. 1 January 1998