Browse by Journal Title

2024

Epigenetic regulatory layers in the 3D nucleus.
Willemin, A. and Szabo, D. and Pombo, A.
Molecular Cell 84 (3): 415-428. 1 February 2024

Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.
Hofman, D.A. and Ruiz-Orera, J. and Yannuzzi, I. and Murugesan, R. and Brown, A. and Clauser, K.R. and Condurat, A.L. and van Dinter, J.T. and Engels, S.A.G. and Goodale, A. and van der Lugt, J. and Abid, T. and Wang, L. and Zhou, K.N. and Vogelzang, J. and Ligon, K.L. and Phoenix, T.N. and Roth, J.A. and Root, D.E and Hubner, N. and Golub, T.R. and Bandopadhayay, P. and van Heesch, S. and Prensner, J.R.
Molecular Cell 84 (2): 261-276. 18 January 2024

2023

mRNA stability and m(6)A are major determinants of subcellular mRNA localization in neurons.
Loedige, I. and Baranovskii, A. and Mendonsa, S. and Dantsuji, S. and Popitsch, N. and Breimann, L. and Zerna, N. and Cherepanov, V. and Milek, M. and Ameres, S. and Chekulaeva, M.
Molecular Cell 83 (15): 2709-2725. 3 August 2023

Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames.
Sandmann, C.L. and Schulz, J.F. and Ruiz-Orera, J. and Kirchner, M. and Ziehm, M. and Adami, E. and Marczenke, M. and Christ, A. and Liebe, N. and Greiner, J. and Schoenenberger, A. and Mücke, M.B. and Liang, N. and Moritz, R.L. and Sun, Z. and Deutsch, E.W. and Gotthardt, M. and Mudge, J.M. and Prensner, J.R. and Willnow, T.E. and Mertins, P. and van Heesch, S. and Hubner, N.
Molecular Cell 83 (6): 994-1011.e18. 16 March 2023

2022

SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA.
Maharana, S. and Kretschmer, S. and Hunger, S. and Yan, X. and Kuster, D. and Traikov, S. and Zillinger, T. and Gentzel, M. and Elangovan, S. and Dasgupta, P. and Chappidi, N. and Lucas, N. and Maser, K.I. and Maatz, H. and Rapp, A. and Marchand, V. and Chang, Y.T. and Motorin, Y. and Hubner, N. and Hartmann, G. and Hyman, A.A. and Alberti, S. and Lee-Kirsch, M.A.
Molecular Cell 82 (19): 3712-3728.e10. 6 October 2022

The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition.
Zonderland, G. and Vanzo, R. and Amitash, S. and Martín-Doncel, E. and Coscia, F. and Mund, A. and Lerdrup, M. and Benada, J. and Boos, D. and Toledo, L.
Molecular Cell 82 (18): 3350-3365. 15 September 2022

A high-resolution map of human RNA translation.
Chothani, S.P. and Adami, E. and Widjaja, A.A. and Langley, S.R. and Viswanathan, S. and Pua, C.J. and Zhihao, N.T. and Harmston, N. and D'Agostino, G. and Whiffin, N. and Mao, W. and Ouyang, J.F. and Lim, W.W. and Lim, S. and Lee, C.Q.E. and Grubman, A. and Chen, J. and Kovalik, J.P. and Tryggvason, K. and Polo, J.M. and Ho, L. and Cook, S.A. and Rackham, O.J.L. and Schafer, S.
Molecular Cell 82 (15): 2885-2899.e8. 4 August 2022

Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20.
Vieira e Vieira, C.H. and Dauksaite, V. and Sporbert, A. and Gotthardt, M. and Selbach, M.
Molecular Cell 82 (11): 2069-2083. 2 June 2022

ATACing single cells with phages.
Maschmeyer, P. and Haas, S.
Molecular Cell 82 (2): 234-236. 20 January 2022

Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus.
Gjaltema, R.A.F. and Schwämmle, T. and Kautz, P. and Robson, M. and Schöpflin, R. and Ravid Lustig, L. and Brandenburg, L. and Dunkel, I. and Vechiatto, C. and Ntini, E. and Mutzel, V. and Schmiedel, V. and Marsico, A. and Mundlos, S. and Schulz, E.G.
Molecular Cell 82 (1): 190-208.e17. 6 January 2022

2021

The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
Heider, M. and Eichner, R. and Stroh, J. and Morath, V. and Kuisl, A. and Zecha, J. and Lawatscheck, J. and Baek, K. and Garz, A.K. and Rudelius, M. and Deuschle, F.C. and Keller, U. and Lemeer, S. and Verbeek, M. and Götze, K.S. and Skerra, A. and Weber, W.A. and Buchner, J. and Schulman, B.A. and Kuster, B. and Fernández-Sáiz, V. and Bassermann, F.
Molecular Cell 81 (6): 1170-1186. 18 March 2021

Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Nikolay, R. and Hilal, T. and Schmidt, S. and Qin, B. and Schwefel, D. and Vieira-Vieira, C.H. and Mielke, T. and Bürger, J. and Loerke, J. and Amikura, K. and Flügel, T. and Ueda, T. and Selbach, M. and Deuerling, E. and Spahn, C.M.T.
Molecular Cell 81 (6): 1200-1215. 18 March 2021

Protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit.
Kraushar, M.L. and Krupp, F. and Harnett, D. and Turko, P. and Ambrozkiewicz, M.C. and Sprink, T. and Imami, K. and Günnigmann, M. and Zinnall, U. and Vieira-Vieira, C.H. and Schaub, T. and Münster-Wandowski, A. and Bürger, J. and Borisova, E. and Yamamoto, H. and Rasin, M.R. and Ohler, U. and Beule, D. and Mielke, T. and Tarabykin, V. and Landthaler, M. and Kramer, G. and Vida, I. and Selbach, M. and Spahn, C.M.T.
Molecular Cell 81 (2): 304-322. 21 January 2021

2020

Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription.
Cossa, G. and Roeschert, I. and Prinz, F. and Baluapuri, A. and Silveira Vidal, R. and Schülein-Völk, C. and Chang, Y.C. and Ade, C.P. and Mastrobuoni, G. and Girard, C. and Kumar, A. and Wortmann, L. and Walz, S. and Lührmann, R. and Kempa, S. and Kuster, B. and Wolf, E. and Mumberg, D. and Eilers, M.
Molecular Cell 77 (6): 1322-1339. 19 March 2020

A conserved noncoding locus regulates random monoallelic Xist expression across a topological boundary.
Galupa, R. and Nora, E.P. and Worsley-Hunt, R. and Picard, C. and Gard, C. and van Bemmel, J.G. and Servant, N. and Zhan, Y. and El Marjou, F. and Johanneau, C. and Diabangouaya, P. and Le Saux, A. and Lameiras, S. and Pipoli da Fonseca, J. and Loos, F. and Gribnau, J. and Baulande, S. and Ohler, U. and Giorgetti, L. and Heard, E.
Molecular Cell 77 (2): 352-367. 16 January 2020

2019

Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence.
Zhang, H. and Alsaleh, G. and Feltham, J. and Sun, Y. and Napolitano, G. and Riffelmacher, T. and Charles, P. and Frau, L. and Hublitz, P. and Yu, Z. and Mohammed, S. and Ballabio, A. and Balabanov, S. and Mellor, J. and Simon, A.K.
Molecular Cell 76 (1): 110-125. 3 October 2019

Conserved pseudoknots in lncRNA MEG3 are essential for stimulation of the p53 pathway.
Uroda, T. and Anastasakou, E. and Rossi, A. and Teulon, J.M. and Pellequer, J.L. and Annibale, P. and Pessey, O. and Inga, A. and Chillón, I. and Marcia, M.
Molecular Cell 75 (5): 982-995. 5 September 2019

Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis.
Wild, P. and Susperregui, A. and Piazza, I. and Dörig, C. and Oke, A. and Arter, M. and Yamaguchi, M. and Hilditch, A.T. and Vuina, K. and Chan, K.C. and Gromova, T. and Haber, J.E. and Fung, J.C. and Picotti, P. and Matos, J.
Molecular Cell 75 (4): 859-874. 22 August 2019

Regulatory landscaping: how enhancer-promoter communication is sculpted in 3D.
Robson, M.I. and Ringel, A.R. and Mundlos, S.
Molecular Cell 74 (6): 1110-1122. 20 June 2019

FIP200 claw domain binding to p62 promotes autophagosome formation at ubiquitin condensates.
Turco, E. and Witt, M. and Abert, C. and Bock-Bierbaum, T. and Su, M.Y. and Trapannone, R. and Sztacho, M. and Danieli, A. and Shi, X. and Zaffagnini, G. and Gamper, A. and Schuschnig, M. and Fracchiolla, D. and Bernklau, D. and Romanov, J. and Hartl, M. and Hurley, J.H. and Daumke, O. and Martens, S.
Molecular Cell 74 (2): 330-346. 18 April 2019

R-loops enhance polycomb repression at a subset of developmental regulator genes.
Skourti-Stathaki, K. and Torlai Triglia, E. and Warburton, M. and Voigt, P. and Bird, A. and Pombo, A.
Molecular Cell 73 (5): 930-945. 7 March 2019

Small and large ribosomal subunit deficiencies lead to distinct gene expression signatures that reflect cellular growth rate.
Cheng, Z. and Mugler, C.F. and Keskin, A. and Hodapp, S. and Chan, L.Y.L. and Weis, K. and Mertins, P. and Regev, A. and Jovanovic, M. and Brar, G.A.
Molecular Cell 73 (1): 36-47. 3 January 2019

2018

The chromatin reader ZMYND8 regulates Igh enhancers to promote immunoglobulin class switch recombination.
Delgado-Benito, V. and Rosen, D.B. and Wang, Q. and Gazumyan, A. and Pai, J.A. and Oliveira, T.Y. and Sundaravinayagam, D. and Zhang, W. and Andreani, M. and Keller, L. and Kieffer-Kwon, K.R. and Pękowska, A. and Jung, S. and Driesner, M. and Subbotin, R.I. and Casellas, R. and Chait, B.T. and Nussenzweig, M.C. and Di Virgilio, M.
Molecular Cell 72 (4): 636-649. 15 November 2018

Exon junction complexes suppress spurious splice sites to safeguard transcriptome integrity.
Boehm, V. and Britto-Borges, T. and Steckelberg, A.L. and Singh, K.K. and Gerbracht, J.V. and Gueney, E. and Blazquez, L. and Altmüller, J. and Dieterich, C. and Gehring, N.H.
Molecular Cell 72 (3): 482-495. 1 November 2018

Phosphorylation of the ribosomal protein RPL12/uL11 affects translation during mitosis.
Imami, K. and Milek, M. and Bogdanow, B. and Yasuda, T. and Kastelic, N. and Zauber, H. and Ishihama, Y. and Landthaler, M. and Selbach, M.
Molecular Cell 72 (1): 84-98. 4 October 2018

mHTT seeding activity: a marker of disease progression and neurotoxicity in models of Huntington's disease.
Ast, A. and Buntru, A. and Schindler, F. and Hasenkopf, R. and Schulz, A. and Brusendorf, L. and Klockmeier, K. and Grelle, G. and McMahon, B. and Niederlechner, H. and Jansen, I. and Diez, L. and Edel, J. and Boeddrich, A. and Franklin, S.A. and Baldo, B. and Schnoegl, S. and Kunz, S. and Purfürst, B. and Gaertner, A. and Kampinga, H.H. and Morton, A.J. and Petersén, Å. and Kirstein, J. and Bates, G.P. and Wanker, E.E.
Molecular Cell 71 (5): 675-688. 6 September 2018

Bacterial RNA biology on a genome scale.
Hör, J. and Gorski, S.A. and Vogel, J.
Molecular Cell 70 (5): 785-799. 7 June 2018

RNA helicase DDX1 converts RNA G-quadruplex structures into R-loops to promote IgH class switch recombination.
Ribeiro de Almeida, C. and Dhir, S. and Dhir, A. and Moghaddam, A.E. and Sattentau, Q. and Meinhart, A. and Proudfoot, N.J.
Molecular Cell 70 (4): 650-662. 17 May 2018

HMGB2 loss upon senescence entry disrupts genomic organization and induces CTCF clustering across cell types.
Zirkel, A. and Nikolic, M. and Sofiadis, K. and Mallm, J.P. and Brackley, C.A. and Gothe, H. and Drechsel, O. and Becker, C. and Altmüller, J. and Josipovic, N. and Georgomanolis, T. and Brant, L. and Franzen, J. and Koker, M. and Gusmao, E.G. and Costa, I.G. and Ullrich, R.T. and Wagner, W. and Roukos, V. and Nürnberg, P. and Marenduzzo, D. and Rippe, K. and Papantonis, A.
Molecular Cell 70 (4): 730-744.e6. 17 May 2018

2017

Circ-ZNF609 is a circular RNA that can be translated and functions in myogenesis.
Legnini, I. and Di Timoteo, G. and Rossi, F. and Morlando, M. and Briganti, F. and Sthandier, O. and Fatica, A. and Santini, T. and Andronache, A. and Wade, M. and Laneve, P. and Rajewsky, N. and Bozzoni, I.
Molecular Cell 66 (1): 22-37.e9. 6 April 2017

Translation of circRNAs.
Pamudurti, N.R. and Bartok, O. and Jens, M. and Ashwal-Fluss, R. and Stottmeister, C. and Ruhe, L. and Hanan, M. and Wyler, E. and Perez-Hernandez, D. and Ramberger, E. and Shenzis, S. and Samson, M. and Dittmar, G. and Landthaler, M. and Chekulaeva, M. and Rajewsky, N. and Kadener, S.
Molecular Cell 66 (1): 9-21. 6 April 2017

Identification of an RNA polymerase III regulator linked to disease-associated protein aggregation.
Sin, O. and de Jong, T. and Mata-Cabana, A. and Kudron, M. and Zaini, M.A. and Aprile, F.A. and Seinstra, R.I. and Stroo, E. and Prins, R.W. and Martineau, C.N. and Wang, H.H. and Hogewerf, Wytse and Steinhof, A. and Wanker, E.E. and Vendruscolo, M. and Calkhoven, C.F. and Reinke, V. and Guryev, V. and Nollen, E.A.A.
Molecular Cell 65 (6): 1096-1108. 16 March 2017

Deciphering the ubiquitin code.
Dittmar, G. and Selbach, M.
Molecular Cell 65 (5): 779-780. 2 March 2017

A finer print than TADs: PRC1-mediated domains.
Torlai Triglia, E. and Rito, Tiago and Pombo, A.
Molecular Cell 65 (3): 373-375. 2 February 2017

2016

Stefan Jentsch (1955-2016) Obituary.
Sommer, T. and Hoppe, T. and Rape, M.
Cell Press. 15 December 2016

Eyes on translation.
Chekulaeva, M. and Landthaler, M.
Molecular Cell 63 (6): 918-925. 15 September 2016

Mapping the landscape of a eukaryotic degronome.
Geffen, Y. and Appleboim, A. and Gardner, R.G. and Friedman, N. and Sadeh, R. and Ravid, T.
Molecular Cell 63 (6): 1055-1065. 15 September 2016

Sequential poly-ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase.
Weber, A. and Cohen, I. and Popp, O. and Dittmar, G. and Reiss, Y. and Sommer, T. and Ravid, T. and Jarosch, E.
Molecular Cell 63 (5): 827-839. 1 September 2016

OCT4 acts as an integrator of pluripotency and signal-induced differentiation.
Simandi, Z. and Horvath, A. and Wright, L.C. and Cuaranta-Monroy, I. and De Luca, I. and Karolyi, K. and Sauer, S. and Deleuze, J.F. and Gudas, L.J. and Cowley, S.M. and Nagy, L.
Molecular Cell 63 (4): 647-661. 18 August 2016

The Lupus autoantigen La prevents Mis-channeling of tRNA fragments into the human microRNA pathway.
Hasler, D. and Lehmann, G. and Murakawa, Y. and Klironomos, F. and Jakob, L. and Grässer, F.A. and Rajewsky, N. and Landthaler, M. and Meister, G.
Molecular Cell 63 (1): 110-124. 7 July 2016

Tissue-specific gene repositioning by muscle nuclear membrane proteins enhances repression of critical developmental genes during myogenesis.
Robson, M.I. and de Las Heras, J.I. and Czapiewski, R. and Lê Thành, P. and Booth, D.G. and Kelly, D.A. and Webb, S. and Kerr, A.R.W. and Schirmer, E.C.
Molecular Cell 62 (6): 834-847. 16 June 2016

The CUE domain of Cue1 aligns growing ubiquitin chains with Ubc7 for rapid elongation.
von Delbrück, M. and Kniss, A. and Rogov, V.V. and Pluska, L. and Bagola, K. and Löhr, F. and Güntert, P. and Sommer, T. and Dötsch, V.
Molecular Cell 62 (6): 918-928. 16 June 2016

2015

A regression-based analysis of ribosome-profiling data reveals a conserved complexity to mammalian translation.
Fields, A.P. and Rodriguez, E.H. and Jovanovic, M. and Stern-Ginossar, N. and Haas, B.J. and Mertins, P. and Raychowdhury, R. and Hacohen, N. and Carr, S.A. and Ingolia, N.T. and Regev, A. and Weissman, J.S.
Molecular Cell 60 (5): 816-827. 3 December 2015

Perspectives on unidirectional versus divergent transcription.
Duttke, S.H.C. and Lacadie, S.A. and Ibrahim, M.M. and Glass, C.K. and Corcoran, D.L. and Benner, C. and Heinz, S. and Kadonaga, J.T. and Ohler, U.
Molecular Cell 60 (3): 348-349. 5 November 2015

Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed.
Rybak-Wolf, A. and Stottmeister, C. and Glažar, P. and Jens, M. and Pino, N. and Giusti, S. and Hanan, M. and Behm, M. and Bartok, O. and Ashwal-Fluss, R. and Herzog, M. and Schreyer, L. and Papavasileiou, P. and Ivanov, A. and Öhman, M. and Refojo, D. and Kadener, S. and Rajewsky, N.
Molecular Cell 58 (5): 870-885. 4 June 2015

Single-cell transcriptomics enters the age of mass production.
Junker, J.P. and van Oudenaarden, A.
Molecular Cell 58 (4): 563-564. 21 May 2015

High-resolution chromatin dynamics during a yeast stress response.
Weiner, A. and Hsieh, T.H.S. and Appleboim, A. and Chen, H.V. and Rahat, A. and Amit, I. and Rando, O.J. and Friedman, N.
Molecular Cell 58 (2): 371-386. 16 April 2015

Human promoters are intrinsically directional.
Duttke, S.H.C. and Lacadie, S.A. and Ibrahim, M.M. and Glass, C.K. and Corcoran, D.L. and Benner, C. and Heinz, S. and Kadonaga, J.T. and Ohler, U.
Molecular Cell 57 (4): 674-684. 19 February 2015

2014

circRNA biogenesis competes with pre-mRNA splicing.
Ashwal-Fluss, R. and Meyer, M. and Pamudurti, N.R. and Ivanov, A. and Bartok, O. and Hanan, M. and Evantal, N. and Memczak, S. and Rajewsky, N. and Kadener, S.
Molecular Cell 56 (1): 55-66. 2 October 2014

Unambiguous identification of miRNA:target site interactions by different types of ligation reactions.
Grosswendt, S. and Filipchyk, A. and Manzano, M. and Klironomos, F. and Schilling, M. and Herzog, M. and Gottwein, E. and Rajewsky, N.
Molecular Cell 54 (6): 1042-1054. 19 June 2014

MOV10 is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.
Gregersen, L.H. and Schueler, M. and Munschauer, M. and Mastrobuoni, G. and Chen, W. and Kempa, S. and Dieterich, C. and Landthaler, M.
Molecular Cell 54 (4): 573-585. 22 May 2014

2013

The ZFP-1(AF10)/DOT-1 complex opposes H2B ubiquitination to reduce Pol II transcription.
Cecere, G. and Hoersch, S. and Jensen, M.B. and Dixit, S. and Grishok, A.
Molecular Cell 50 (6): 894-907. 27 June 2013

Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Bagola, K. and von Delbrück, M. and Dittmar, G. and Scheffner, M. and Ziv, I. and Glickman, M.H. and Ciechanover, A. and Sommer, T.
Molecular Cell 50 (4): 528-539. 23 May 2013

The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO.
Mueller-Rischart, A.K. and Pilsl, A. and Beaudette, P. and Patra, M. and Hadian, K. and Funke, M. and Peis, R. and Deinlein, A. and Schweimer, C. and Kuhn, P.H. and Lichtenthaler, S.F. and Motori, E. and Hrelia, S. and Wurst, W and Truembach, D. and Langer, T. and Krappmann, D. and Dittmar, G. and Tatzelt, J. and Winklhofer, K.F.
Molecular Cell 49 (5): 908-921. 7 March 2013

Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.
Staber, P.B. and Zhang, P. and Ye, M. and Welner, R.S. and Nombela-Arrieta, C. and Bach, C. and Kerenyi, M. and Bartholdy, B.A. and Zhang, H. and Alberich-Jorda, M. and Lee, S. and Yang, H. and Ng, F. and Zhang, J. and Leddin, M. and Silberstein, L.E. and Hoefler, G. and Orkin, S.H. and Goettgens, B. and Rosenbauer, F. and Huang, G. and Tenen, D.G.
Molecular Cell 49 (5): 934-946. 7 March 2013

Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathways.
Anton, F. and Dittmar, G. and Langer, T. and Escobar-Henriques, M.
Molecular Cell 49 (3): 487-498. 7 February 2013

Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes.
Uhlenhaut, N.H. and Barish, G.D. and Yu, R.T. and Downes, M. and Karunasiri, M. and Liddle, C. and Schwalie, P. and Hübner, N. and Evans, R.M.
Molecular Cell 49 (1): 158-171. 10 January 2013

2012

The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation.
Shabek, N. and Herman-Bachinsky, Y. and Buchsbaum, S. and Lewinson, O. and Haj-Yahya, M. and Hejjaoui, M. and Lashuel, H.A. and Sommer, T. and Brik, A. and Ciechanover, A.
Molecular Cell 48 (1): 87-97. 12 October 2012

Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase.
Karanam, K. and Kafri, R. and Loewer, A. and Lahav, G.
Molecular Cell 47 (2): 320-329. 27 July 2012

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz, A.G. and Munschauer, M. and Schwanhaeusser, B. and Vasile, A. and Murakawa, Y. and Schueler, M. and Youngs, N. and Penfold-Brown, D. and Drew, K. and Milek, M. and Wyler, E. and Bonneau, R. and Selbach, M. and Dieterich, C. and Landthaler, M.
Molecular Cell 46 (5): 674-690. 8 June 2012

When noisy neighbors are a blessing: analysis of gene expression noise identifies coregulated genes.
Junker, J.P. and van Oudenaarden, A.
Molecular Cell 45 (4): 437-438. 24 February 2012

2011

In vivo and transcriptome-wide identification of RNA binding protein target sites.
Jungkamp, A.C. and Stoeckius, M. and Mecenas, D. and Gruen, D. and Mastrobuoni, G. and Kempa, S. and Rajewsky, N.
Molecular Cell 44 (5): 828-840. 9 December 2011

Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR.
Lebedeva, S. and Jens, M. and Theil, K. and Schwanhaeusser, B. and Selbach, M. and Landthaler, M. and Rajewsky, N.
Molecular Cell 43 (3): 340-352. 5 August 2011

Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.
Mukherjee, N. and Corcoran, D.L. and Nusbaum, J.D. and Reid, D.W. and Georgiev, S. and Hafner, M. and Ascano, M. and Tuschl, T. and Ohler, U. and Keene, J.D.
Molecular Cell 43 (3): 327-339. 5 August 2011

Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.
Bothmer, A. and Robbiani, D.F. and Di Virgilio, M. and Bunting, S.F. and Klein, I.A. and Feldhahn, N. and Barlow, J. and Chen, H.T. and Bosque, D. and Callen, E. and Nussenzweig, A. and Nussenzweig, M.C.
Molecular Cell 42 (3): 319-329. 6 May 2011

2010

Global analysis of nascent RNA reveals transcriptional pausing in terminal exons.
Carrillo Oesterreich, F. and Preibisch, S. and Neugebauer, K.M.
Molecular Cell 40 (4): 571-581. 24 November 2010

Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.
Buchberger, A. and Bukau, B. and Sommer, T.
Molecular Cell 40 (2): 238-252. 22 October 2010

A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
Hinz, M. and Stilmann, M. and Coel Arslan, S. and Khanna, K.K. and Dittmar, G. and Scheidereit, C.
Molecular Cell 40 (1): 63-74. 8 October 2010

Chaperones get RISC loaded.
Landthaler, M.
Molecular Cell 39 (2): 161-162. 30 July 2010

Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2.
Kanhere, A. and Viiri, K. and Araujo, C.C. and Rasaiyaah, J. and Bouwman, R.D. and Whyte, W.A. and Pereira, C.F. and Brookes, E. and Walker, K. and Bell, G.W. and Pombo, A. and Fisher, A.G. and Young, R.A. and Jenner, R.G.
Molecular Cell 38 (5): 675-688. 11 June 2010

2009

Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
Horn, S.C. and Hanna, J. and Hirsch, C. and Volkwein, C. and Schütz, A. and Heinemann, U. and Sommer, T. and Jarosch, E.
Molecular Cell 36 (5): 782-793. 11 December 2009

A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IκB kinase activation.
Stilmann, M. and Hinz, M. and Coel Arslan, S. and Zimmer, A. and Schreiber, V. and Scheidereit, C.
Molecular Cell 36 (3): 365-378. 13 November 2009

Ribosomal protein S7 is both a regulator and a substrate of MDM2.
Zhu, Y. and Poyurovsky, M.V. and Li, Y. and Biderman, L. and Stahl, J. and Jacq, X. and Prives, C.
Molecular Cell 35 (3): 316-326. 14 August 2009

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.
Callen, E. and Jankovic, M. and Wong, N. and Zha, S. and Chen, H.T. and Difilippantonio, S. and Di Virgilio, M. and Heidkamp, G. and Alt, F.W. and Nussenzweig, A. and Nussenzweig, M.
Molecular Cell 34 (3): 285-297. 15 May 2009

2008

A human snoRNA with microRNA-like functions.
Ender, C. and Krek, A. and Friedlaender, M.R. and Beitzinger, M. and Weinmann, L. and Chen, W. and Pfeffer, S. and Rajewsky, N. and Meister, G.
Molecular Cell 32 (4): 519-528. 21 November 2008

Modulation of RNA polymerase assembly dynamics in transcriptional regulation.
Gorski, S.A. and Snyder, S.K. and John, S. and Grummt, I. and Misteli, T.
Molecular Cell 30 (4): 486-497. 23 May 2008

Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage.
Batchelor, E. and Mock, C.S. and Bhan, I. and Loewer, A. and Lahav, G.
Molecular Cell 30 (3): 277-289. 9 May 2008

2007

Balancing BMP signaling through integrated inputs into the Smad1 linker.
Sapkota, G. and Alarcon, C. and Spagnoli, F.M. and Brivanlou, A.H. and Massague, J.
Molecular Cell 25 (3): 441-454. 9 February 2007

2006

A genome-wide analysis indicates that yeast pre-mRNA splicing is predominantly posttranscriptional.
Tardiff, D.F. and Lacadie, S.A. and Rosbash, M.
Molecular Cell 24 (6): 917-929. 28 December 2006

Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.
Wegener, E. and Oeckinghaus, A. and Papadopoulou, N. and Lavitas, L. and Schmidt-Supprian, M. and Ferch, U. and Mak, T.W. and Ruland, J. and Heissmeyer, V. and Krappmann, D.
Molecular Cell 23 (1): 13-23. 7 July 2006

2005

Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast.
Lacadie, S.A. and Rosbash, M.
Molecular Cell 19 (1): 65-75. 1 July 2005

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.
Ding, Q. and Xia, W. and Liu, J.C. and Yang, J.Y. and Lee, D.F. and Xia, J. and Bartholomeusz, G. and Li, Y. and Pan, Y. and Li, Z. and Bargou, R.C. and Qin, J. and Lai, C.C. and Tsai, F.J. and Tsai, C.H. and Hung, M.C.
Molecular Cell 19 : 159-170. 1 January 2005

2004

The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF.
Philippar, U. and Schratt, G. and Dieterich, C. and Mueller, J.M. and Galgoczy, P. and Engel, F.B. and Keating, M.T. and Gertler, F. and Schuele, R. and Vingron, M. and Nordheim, A.
Molecular Cell 16 (6): 867-880. 22 December 2004

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
Goehler, H. and Lalowski, M. and Stelzl, U. and Waelter, S. and Stroedicke, M. and Worm, U. and Droege, A. and Lindenberg, K.S. and Knoblich, M. and Haenig, C. and Herbst, M. and Suopanki, J. and Scherzinger, E. and Abraham, C. and Bauer, B. and Hasenbank, R. and Fritzsche, A. and Ludewig, A.H. and Buessow, K. and Coleman, S.H. and Gutekunst, C.A. and Landwehrmeyer, B.G. and Lehrach, H. and Wanker, E.E.
Molecular Cell 15 (6): 853-865. 24 September 2004

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.
Meister, G. and Landthaler, M. and Patkaniowska, A. and Dorsett, Y. and Teng, G. and Tuschl, T.
Molecular Cell 15 (2): 185-197. 23 July 2004

Ras induces mediator complex exchange on C/EBPβ.
Mo, X.M. and Kowenz-Leutz, E. and Xu, H. and Leutz, A.
Molecular Cell 13 (2): 241-250. 30 January 2004

A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
Bourbon, H.M. and Aguilera, A. and Ansari, A.Z. and Asturias, F.J. and Berk, A.J. and Bjorklund, S. and Blackwell, T.K. and Borggrefe, T. and Carey, M. and Carlson, M. and Conaway, J.W. and Conaway, R.C. and Emmons, S.W. and Fondell, J.D. and Freedman, L.P. and Fukasawa, T. and Gustafsson, C.M. and Han, M. and He, X. and Herman, P.K. and Hinnebusch, A.G. and Holmberg, S. and Holstege, F.C. and Jaehning, J.A. and Kim, Y.J. and Kuras, L. and Leutz, A. and Lis, J.T. and Meisterernest, M. and Naar, A.M. and Nasmyth, K. and Parvin, J.D. and Ptashne, M. and Reinberg, D. and Ronne, H. and Sadowski, I. and Sakurai, H. and Sipiczki, M. and Sternberg, P.W. and Stillman, D.J. and Strich, R. and Struhl, K. and Svejstrup, J.Q. and Tuck, S. and Winston, F. and Roeder, R.G. and Kornberg, R.D.
Molecular Cell 14 (5): 553-557. 1 January 2004

Healing the wounds inflicted by Sleeping Beauty transposition by double-strand break repair in mammalian somatic cells.
Izsvak, Z. and Stuewe, E.E. and Fiedler, D. and Katzer, A. and Jeggo, P.A. and Ivics, Z.
Molecular Cell 13 (2): 279-290. 1 January 2004

Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation.
Meusser, B. and Sommer, T.
Molecular Cell 14 (2): 247-258. 1 January 2004

2002

DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters.
Sporbert, A. and Gahl, A. and Ankerhold, R. and Leonhardt, H. and Cardoso, M.C.
Molecular Cell 10 (6): 1355-1365. December 2002

Phosphorylation by protein kinase CK2: A signaling switch for the caspase-inhibiting protein ARC.
Li, P.F. and Li, J.C. and Mueller, E.C. and Otto, A. and Dietz, R. and von Harsdorf, R.
Molecular Cell 10 (2): 247-258. August 2002

2000

The level of C/EBP protein is critical for cell migration during Drosophila oogenesis and is tightly controlled by regulated degradation.
Rorth, P. and Szabo, K. and Texido, G.
Molecular Cell 6 : 23-30. 1 July 2000

1999

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src.
Wong, B.R. and Besser, D. and Kim, N. and Arron, J.R. and Vologodskaia, M. and Hanafusa, H. and Choi, Y.
Molecular Cell 4 (6): 1041-1049. December 1999

A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes.
Kowenz-Leutz, E. and Leutz, A.
Molecular Cell 4 (5): 735-743. November 1999

1998

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates.
Sittler, A. and Walter, S. and Wedemeyer, N. and Hasenbank, R. and Scherzinger, E. and Eickhoff, H. and Bates, G.P. and Lehrach, H. and Wanker, E.E.
Molecular Cell 2 (4): 427-436. October 1998

Identification of a tRNA-specific nuclear export receptor.
Kutay, U. and Lipowsky, G. and Izaurralde, E. and Bischoff, F.R. and Schwarzmaier, P. and Hartmann, E. and Goerlich, D.
Molecular Cell 1 : 359-369. 1 January 1998