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2017

SORLA attenuates EphA4 signaling and amyloid, β-induced neurodegeneration.
Huang, T.Y. and Zhao, Y. and Jiang, L.L. and Li, X. and Liu, Y. and Sun, Y. and Piña-Crespo, J.C. and Zhu, B. and Masliah, E. and Willnow, T.E. and Pasquale, E.B. and Xu, H.
Journal of Experimental Medicine 214 (12): 3669-3685. 4 December 2017

Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.
Chen, X. and Poncette, L. and Blankenstein, T.
Journal of Experimental Medicine 214 (11): 3417-3433. 6 November 2017

Developmental origin and maintenance of distinct testicular macrophage populations.
Mossadegh-Keller, N. and Gentek, R. and Gimenez, G. and Bigot, S. and Mailfert, S. and Sieweke, M.H.
Journal of Experimental Medicine 214 (10): 2829-2841. 2 October 2017

Gene silencing and a novel monoallelic expression pattern in distinct CD177 neutrophil subsets.
Eulenberg-Gustavus, C. and Bähring, S. and Maass, P. and Luft, F.C. and Kettritz, R.
Journal of Experimental Medicine 214 (7): 2089-2101. 3 July 2017

2016

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.
Textor, A. and Schmidt, K. and Kloetzel, P.M. and Weißbrich, B. and Perez, C. and Charo, J. and Anders, K. and Sidney, J. and Sette, A. and Schumacher, T.N.M. and Keller, C. and Busch, D.H. and Seifert, U. and Blankenstein, T.
Journal of Experimental Medicine 213 (11): 2333-2348. 17 October 2016

M-CSF improves protection against bacterial and fungal infections after hematopoietic stem/progenitor cell transplantation.
Kandalla, P.K. and Sarrazin, S. and Molawi, K. and Berruyer, C. and Redelberger, D. and Favel, A. and Bordi, C. and de Bentzmann, S. and Sieweke, M.H.
Journal of Experimental Medicine 213 (11): 2269-2279. 10 October 2016

miR-23~27~24 clusters control effector T cell differentiation and function.
Cho, S. and Wu, C.J. and Yasuda, T. and Cruz, L.O. and Khan, A.A. and Lin, L.L. and Nguyen, D.T. and Miller, M. and Lee, H.M. and Kuo, M.L. and Broide, D.H. and Rajewsky, K. and Rudensky, A.Y. and Lu, L.F.
Journal of Experimental Medicine 213 (2): 235-249. 8 February 2016

2014

Progressive replacement of embryo-derived cardiac macrophages with age.
Molawi, K. and Wolf, Y. and Kandalla, P.K. and Favret, J. and Hagemeyer, N. and Frenzel, K. and Pinto, A.R. and Klapproth, K. and Henri, S. and Malissen, B. and Rodewald, H.R. and Rosenthal, N.A. and Bajenoff, M. and Prinz, M. and Jung, S. and Sieweke, M.H.
Journal of Experimental Medicine 211 (11): 2151-2158. 20 October 2014

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.
Lancini, C. and van den Berk, P.C.M. and Vissers, J.H.A. and Gargiulo, G. and Song, J.Y. and Hulsman, D. and Serresi, M. and Tanger, E. and Blom, M. and Vens, C. and van Lohuizen, M. and Jacobs, H. and Citterio, E.
Journal of Experimental Medicine 211 (9): 1759-1777. 25 August 2014

Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression.
Vaeth, M. and Mueller, G. and Stauss, D. and Dietz, L. and Klein-Hessling, S. and Serfling, E. and Lipp, M. and Berberich, I. and Berberich-Siebelt, F.
Journal of Experimental Medicine 211 (3): 545-561. 10 March 2014

2013

Cross talk between Wnt/β-catenin and Irf8 in leukemia progression and drug resistance.
Scheller, M. and Schönheit, J. and Zimmermann, K. and Leser, U. and Rosenbauer, F. and Leutz, A.
Journal of Experimental Medicine 210 (11): 2239-2256. 21 October 2013

Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis.
Soler, A. and Serra, H. and Pearce, W. and Angulo, A. and Guillermet-Guibert, J. and Friedman, L.S. and Viñals, F. and Gerhardt, H. and Casanovas, O. and Graupera, M. and Vanhaesebroeck, B.
Journal of Experimental Medicine 210 (10): 1937-1945. 23 September 2013

Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis.
Augustin, I. and Gross, J. and Baumann, D. and Korn, C. and Kerr, G. and Grigoryan, T. and Mauch, C. and Birchmeier, W. and Boutros, M.
Journal of Experimental Medicine 210 (9): 1761-1777. 26 August 2013

2012

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
Kaji, T. and Ishige, A. and Hikida, M. and Taka, J. and Hijikata, A. and Kubo, M. and Nagashima, T. and Takahashi, Y. and Kurosaki, T. and Okada, M. and Ohara, O. and Rajewsky, K. and Takemori, T.
Journal of Experimental Medicine 209 (11): 2079-2097. 22 October 2012

A role for GPx3 in activity of normal and leukemia stem cells.
Herault, O. and Hope, K.J. and Deneault, E. and Mayotte, N. and Chagraoui, J. and Wilhelm, B.T. and Cellot, S. and Sauvageau, M. and Andrade-Navarro, M.A. and Hebert, J. and Sauvageau, G.
Journal of Experimental Medicine 209 (5): 895-901. 7 May 2012

2011

Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
Steininger, A. and Moebs, M. and Ullmann, R. and Koechert, K. and Kreher, S. and Lamprecht, B. and Anagnostopoulos, I. and Hummel, M. and Richter, J. and Beyer, M. and Janz, M. and Klemke, C.D. and Stein, H. and Doerken, B. and Sterry, W. and Schrock, E. and Mathas, S. and Assaf, C.
Journal of Experimental Medicine 208 (8): 1585-1593. 1 August 2011

Platelet-derived serotonin links vascular disease and tissue fibrosis.
Dees, C. and Akhmetshina, A. and Zerr, P. and Reich, N. and Palumbo, K. and Horn, A. and Juengel, A. and Beyer, C. and Kroenke, G. and Zwerina, J. and Reiter, R. and Alenina, N. and Maroteaux, L. and Gay, S. and Schett, G. and Distler, O. and Distler, J.H.
Journal of Experimental Medicine 208 (5): 961-972. 9 May 2011

2009

NOD2 regulates hematopoietic cell function during graft-versus-host disease.
Penack, O. and Smith, O.M. and Cunningham-Bussel, A. and Liu, X. and Rao, U. and Yim, N. and Na, I.K. and Holland, A.M. and Ghosh, A. and Lu, S.X. and Jenq, R.R. and Liu, C. and Murphy, G.F. and Brandl, K. and van den Brink, M.R.M.
Journal of Experimental Medicine 206 (10): 2101-2110. 28 September 2009

2008

The tight junction protein CAR regulates cardiac conduction and cell-cell communication.
Lisewski, U. and Shi, Y. and Wrackmeyer, U. and Fischer, R. and Chen, C. and Schirdewan, A. and Juettner, R. and Rathjen, F.G. and Poller, W. and Radke, M.H. and Gotthardt, M.
Journal of Experimental Medicine 205 (10): 2369-2379. 29 September 2008

Autoregulation of Th1-mediated inflammation by twist1.
Niesner, U. and Albrecht, I. and Janke, M. and Doebis, C. and Loddenkemper, C. and Lexberg, M.H. and Eulenburg, K. and Kreher, S. and Koeck, J. and Baumgrass, R. and Bonhagen, K. and Kamradt, T. and Enghard, P. and Humrich, J.Y. and Rutz, S. and Schulze-Topphoff, U. and Aktas, O. and Bartfeld, S. and Radbruch, H. and Hegazy, A.N. and Lohning, M. and Baumgart, D.C. and Duchmann, R. and Rudwaleit, M. and Haupl, T. and Gitelman, I. and Krenn, V. and Gruen, J. and Sieper, J. and Zeitz, M. and Wiedenmann, B. and Zipp, F. and Hamann, A. and Janitz, M. and Scheffold, A. and Burmester, G.R. and Chang, H.D. and Radbruch, A.
Journal of Experimental Medicine 205 (8): 1889-1901. 4 August 2008

Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness.
Willimsky, G. and Czeh, M. and Loddenkemper, C. and Gellermann, J. and Schmidt, K. and Wust, P. and Stein, H. and Blankenstein, T.
Journal of Experimental Medicine 205 (7): 1687-1700. 7 July 2008

2007

Antiribosomal-P autoantibodies from psychiatric lupus target a novel neuronal surface protein causing calcium influx and apoptosis.
Matus, S. and Burgos, P.V. and Bravo-Zehnder, M. and Kraft, R. and Porras, O.H. and Farias, P. and Barros, L.F. and Torrealba, F. and Massardo, L. and Jacobelli, S. and Gonzalez, A.
Journal of Experimental Medicine 204 (13): 3221-3234. 24 December 2007

CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells.
Schneider, M.A. and Meingassner, J.G. and Lipp, M. and Moore, H.D. and Rot, A.
Journal of Experimental Medicine 204 (4): 735-745. 16 April 2007

2005

Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection.
Kursar, M. and Hoepken, U.E. and Koch, M. and Koehler, A. and Lipp, M. and Kaufmann, S.H. and Mittruecker, H.W.
Journal of Experimental Medicine 201 (9): 1447-1457. 2 May 2005

2004

CCR7 signals are essential for cortex-medulla migration of developing thymocytes.
Ueno, T. and Saito, F. and Gray, D.H.D. and Kuse, S. and Hieshima, K. and Nakano, H. and Kakiuchi, T. and Lipp, M. and Boyd, R.L. and Takahama, Y.
Journal of Experimental Medicine 200 (4): 493-505. 16 August 2004

c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.
Mathas, S. and Lietz, A. and Anagnostopoulos, I. and Hummel, F. and Wiesner, B. and Janz, M. and Jundt, F. and Hirsch, B. and Joehrens-Leder, K. and Vornlocher, H.P. and Bommert, K. and Stein, H. and Doerken, B.
Journal of Experimental Medicine 199 (8): 1041-1052. 19 April 2004

2003

Tumor rejection by modulation of tumor stromal fibroblasts.
Schueler, T. and Koernig, S. and Blankenstein, T.
Journal of Experimental Medicine 198 (10): 1487-1493. 17 November 2003

Regulation of dendritic cell migration to the draining lymph node: Impact on T lymphocyte traffic and priming.
Martin-Fontecha, A. and Sebastiani, S. and Hoepken, U.E. and Uguccioni, M. and Lipp, M. and Lanzavecchia, A. and Sallusto, F.
Journal of Experimental Medicine 198 (4): 615-621. 18 August 2003

Differentiation of effector/memory V ae 2 T cells and migratory routes in lymph nodes or inflammatory sites.
Dieli, F. and Poccia, F. and Lipp, M. and Sireci, G. and Caccamo, N. and Di Sano, C. and Salerno, A.
Journal of Experimental Medicine 198 (3): 391-397. 4 August 2003

Cooperating mechanisms of CXCR5 and CCR7 in development and organization of secondary lymphoid organs.
Ohl, L. and Henning, G. and Krautwald, S. and Lipp, M. and Hardtke, S. and Bernhardt, G. and Pabst, O. and Foerster, R.
Journal of Experimental Medicine 197 (9): 1199-1204. 5 May 2003

Treatment of relapsing paralysis in experimental encephalomyelitis by targeting Th1 cells through atorvastatin.
Aktas, O. and Waiczies, S. and Smorodchenko, A. and Dorr, J. and Seeger, B. and Prozorovski, T. and Sallach, S. and Endres, M. and Brocke, S. and Nitsch, R. and Zipp, F.
Journal of Experimental Medicine 197 (6): 725-733. 17 March 2003

2002

Nucleolin as activator of human papillomavirus type 18 oncogene transcription in cervical cancer.
Grinstein, E. and Wernet, P. and Snijders, P.J.F. and Rosl, F. and Weinert, I. and Jia, W.T. and Kraft, R. and Schewe, C. and Schwabe, M. and Hauptmann, S. and Dietel, M. and Meijer, C.J.L.M. and Royer, H.D.
Journal of Experimental Medicine 196 (8): 1067-1078. 21 October 2002

Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
Hinz, M. and Lemke, P. and Anagnostopoulos, I. and Hacker, C. and Krappmann, D. and Mathas, S. and Doerken, B. and Zenke, M. and Stein, H. and Scheidereit, C.
Journal of Experimental Medicine 196 (5): 605-617. 2 September 2002

Chemokine requirements for B cell entry to lymph nodes and Peyers patches.
Okada, T. and Ngo, V.N. and Ekland, E.H. and Foerster, R. and Lipp, M. and Littman, D.R. and Cyster, J.G.
Journal of Experimental Medicine 196 (1): 65-75. 1 July 2002

Inhibition of methylcholanthrene-induced carcinogenesis by an interferon gamma receptor-dependent foreign body reaction.
Qin, Z. and Kim, H.J. and Hemme, J. and Blankenstein, T.
Journal of Experimental Medicine 195 (11): 1479-1490. 3 June 2002

2001

CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: Modulation by FTY720.
Henning, G. and Ohl, H. and Junt, T. and Reiterer, P. and Brinkmann, V. and Nakano, H. and Hohenberger, W. and Lipp, M. and Foerster, R.
Journal of Experimental Medicine 194 (12): 1875-1881. 17 December 2001

Generation of tumor-associated cytotoxic T lymphocytes requires interleukin 4 from CD8+ T cells.
Schueler, T. and Kammertoens, T. and Preiss, S. and Debs, P. and Noben-Trauth, N. and Blankenstein, T.
Journal of Experimental Medicine 194 (12): 1767-1775. 17 December 2001

Tumor rejection by disturbing tumor stroma cell interactions.
Ibe, S. and Qin, Z.H. and Schueler, T. and Preiss, S. and Blankenstein, T.
Journal of Experimental Medicine 194 (11): 1549-1559. 3 December 2001

Aberrant high expression of B lymphocyte chemokine (BLC/CXCL13) by C11b+CD11c+ dendritic cells in murine lupus and preferential chemotaxis of B1 cells towards BLC.
Ishikawa, S. and Sato, T. and Abe, M. and Nagai, S. and Onai, N. and Yoneyama, H. and Zhang, Y.Y. and Suzuki, T. and Hashimoto, S. and Shirai, T. and Lipp, M. and Matsushima, K.
Journal of Experimental Medicine 193 (12): 1393-1402. 18 June 2001

2000

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production.
Breitfeld, D. and Ohl, L. and Kremmer, E. and Ellwart, J. and Sallusto, F. and Lipp, M. and Foerster, R.
Journal of Experimental Medicine 192 (11): 1545-1551. 4 December 2000

CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function.
Schaerli, P. and Willimann, K. and Lang, A.B. and Lipp, M. and Loetscher, P. and Moser, B.
Journal of Experimental Medicine 192 (11): 1553-1562. 4 December 2000

Suppression of tumorigenicity in breast cancer cells by the microfilament protein profilin 1.
Janke, J. and Schlueter, K. and Jandrig, B. and Theile, M. and Koelble, K. and Arnold, W. and Grinstein, E. and Schwartz, A. and Estevez-Schwarz, L. and Schlag, P.M. and Jockusch, B.M. and Scherneck, S.
Journal of Experimental Medicine 191 (10): 1675-1685. 15 May 2000

Induction and suppression of an autoimmune disease by oligomerized T cell epitopes: enhanced in vivo potency of encephalitogenic peptides.
Falk, K. and Roetzschke, O. and Santambrogio, L. and Dorf, M.E. and Brosnan, C. and Strominger, J.L.
Journal of Experimental Medicine 191 (4): 717-730. 21 February 2000

1999

Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.
Walker, L.S.K. and Gulbranson-Judge, A. and Flynn, S. and Brocker, T. and Raykundalia, C. and Goodall, M. and Foerster, R. and Lipp, M. and Lane, P.
Journal of Experimental Medicine 190 (8): 1115-1122. 18 October 1999

T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice.
Schueler, T. and Qin, Z. and Ibe, S. and Noben-Trauth, N. and Blankenstein, T.
Journal of Experimental Medicine 189 (5): 803-810. 1 March 1999

1998

Interleukin 4 gene-defective mice reconstituted with wild-type bone marrow fail to produce normal immunoglobulin E levels.
Lange, C. and Schueler, T. and Blankenstein, T.
Journal of Experimental Medicine 187 (9): 1487-1493. 4 May 1998

1997

Impaired inflammatory responses in the reverse arthus reaction through genetic deletion of the C5a receptor.
Hoepken, U.E. and Lu, B. and Gerard, N.P. and Gerard, C.
Journal of Experimental Medicine 186 (5): 749-756. 29 August 1997

1996

Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse.
Morawetz, R.A. and Gabriele, L. and Rizzo, L.V. and Noben-Trauth, N. and Kuehn, R. and Rajewsky, K. and Mueller, W. and Doherty, T.M. and Finkelman, F. and Coffman, R.L. and Morse, H.C.
Journal of Experimental Medicine 184 (5): 1651-1661. 1 November 1996

Proteasome alpha-type subunit C9 is a primary target of autoantibodies in sera of patients with myositis and systemic lupus erythematosus.
Feist, E. and Doerner, T. and Kuckelkorn, U. and Schmidtke, G. and Micheel, B. and Hiepe, F. and Burmester, G.R. and Kloetzel, P.M.
Journal of Experimental Medicine 184 (4): 1313-1318. 1 October 1996

Remnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes.
Sinnis, P. and Willnow, T.E. and Briones, M.R. and Herz, J. and Nussenzweig, V.
Journal of Experimental Medicine 184 (3): 945-954. 1 September 1996

T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.
Davidson, N.J. and Leach, M.W. and Fort, M.M. and Thompson-Snipes, L. and Kuehn, R. and Mueller, W. and Berg, D.J. and Rennick, D.M.
Journal of Experimental Medicine 184 (1): 241-251. 1 July 1996

Blocking of transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in scid mice.
Bargou, R.C. and Wagener, C. and Bommert, K. and Arnold, W. and Daniel, P.T. and Mapara, M.Y. and Grinstein, E. and Royer, H.D. and Doerken, B.
Journal of Experimental Medicine 183 (3): 1205-1213. 1 March 1996

Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice.
Carrera, L. and Gazzinelli, R.T. and Badolato, R. and Hieny, S. and Mueller, W. and Kuehn, R. and Sacks, D.L.
Journal of Experimental Medicine 183 (2): 515-526. 1 February 1996

1995

Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses.
Berg, D.J. and Leach, M.W. and Kuehn, R. and Rajewsky, K. and Mueller, W. and Davidson, N.J. and Rennick, D.
Journal of Experimental Medicine 182 (1): 99-108. 1 July 1995

Molecular mimicry between the immunodominant ribosomal protein PO of Trypanosoma cruzi and a functional epitope on the human beta1-adrenergic receptor.
Ferrari, I. and Levin, M.J. and Wallukat, G. and Elies, R. and Lebesgue, D. and Chiale, P. and Elizari, M. and Rosenbaum, M. and Hoebeke, J.
Journal of Experimental Medicine 182 (1): 59-65. 1 July 1995

1994

Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells.
Schmitz, J. and Thiel, A. and Kuehn, R. and Rajewsky, K. and Mueller, W. and Assenmacher, M. and Radbruch, A.
Journal of Experimental Medicine 179 (4): 1349-53. 1 April 1994

1993

Expression of tumor necrosis factor by different tumor cell lines results either in tumor suppression or augmented metastasis.
Qin, Z. and Krueger-Krasagakes, S. and Kunzendorf, U. and Hock, H. and Diamantstein, T. and Blankenstein, T.
Journal of Experimental Medicine 178 (1): 355-360. 1 July 1993

Characterization of a novel Hodgkin cell-line, HD-MyZ, HD-Myr, with myelomonocytic features mimicking Hodgkin's disease in severe combined immunodeficient mice.
Bargou, R.C. and Mapara, M.Y. and Zugck, C. and Daniel, P.T. and Pawlita, M. and Doehner, H. and Doerken, B.
Journal of Experimental Medicine 177 (5): 1257-1268. 1 May 1993

Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.
Breit, T.M. and Mol, E.J. and Wolvers-Tettero, I.L. and Ludwig, W.D. and van Wering, E.R. and van Dongen, J.J.
Journal of Experimental Medicine 177 (4): 965-977. 1 April 1993

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