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A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice.
Brenner, D., Sieverding, K., Srinidhi, J., Zellner, S., Secker, C., Yilmaz, R., Dyckow, J., Amr, S., Ponomarenko, A., Tunaboylu, E., Douahem, Y., Schlag, J.S., Rodríguez Martínez, L., Kislinger, G., Niemann, C., Nalbach, K., Ruf, W.P., Uhl, J., Hollenbeck, J., Schirmer, L., Catanese, A., Lobsiger, C.S., Danzer, K.M., Yilmazer-Hanke, D., Münch, C., Koch, P., Freischmidt, A., Fetting, M., Behrends, C., Parlato, R. and Weishaupt, J.H.
Journal of Experimental Medicine 221 (5): e20221190. 22 March 2024

GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao, Y., Du Jiang, P., Chao, B.N., Cagdas, D., Kubo, S., Balasubramaniyam, A., Zhang, Y., Shadur, B., NaserEddin, A., Folio, L.R., Schwarz, B., Bohrnsen, E., Zheng, L., Lynberg, M., Gottlieb, S., Leney-Greene, M.A., Park, A.Y., Tezcan, I., Akdogan, A., Gocmen, R., Onder, S., Rosenberg, A., Soilleux, E.J., Johnson, E., Jackson, P.K., Demeter, J., Chauvin, S.D., Paul, F., Selbach, M., Bulut, H., Clatworthy, M.R., Tuong, Z.K., Zhang, H., Stewart, B.J., Bosio, C.M., Stepensky, P., Clare, S., Ganesan, S., Pascall, J.C., Daumke, O., Butcher, G.W., McMichael, A.J., Simon, A.K. and Lenardo, M.J.
Journal of Experimental Medicine 219 (6): e20201405. 6 June 2022

B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice.
Lee, M.S.J., Inoue, T., Ise, W., Matsuo-Dapaah, J., Wing, J.B., Temizoz, B., Kobiyama, K., Hayashi, T., Patil, A., Sakaguchi, S., Simon, A.K., Bezbradica, J.S., Nagatoishi, S., Tsumoto, K., Inoue, J.I., Akira, S., Kurosaki, T., Ishii, K.J. and Coban, C.
Journal of Experimental Medicine 219 (2): e20211336. 7 February 2022

A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15.
Patsalos, A., Halasz, L., Medina-Serpas, M.A., Berger, W.K., Daniel, B., Tzerpos, P., Kiss, M., Nagy, G., Fischer, C., Simandi, Z., Varga, T. and Nagy, L.
Journal of Experimental Medicine 219 (1): e20210420. 3 January 2022

Encephalitis patient-derived monoclonal GABA(A) receptor antibodies cause epileptic seizures.
Kreye, J., Wright, S.K., van Casteren, A., Stoeffler, L., Machule, M.L., Reincke, S.M., Nikolaus, M., van Hoof, S., Sanchez-Sendin, E., Homeyer, M.A., Gómez, C.C., Kornau, H.C., Schmitz, D., Kaindl, A.M., Boehm-Sturm, P., Mueller, S., Wilson, M.A., Upadhya, M.A., Dhangar, D.R., Greenhill, S., Woodhall, G., Turko, P., Vida, I., Garner, C.C., Wickel, J., Geis, C., Fukata, Y., Fukata, M. and Prüss, H.
Journal of Experimental Medicine 218 (11): e20210012. 1 November 2021

Familial thrombocytopenia due to a complex structural variant resulting in a WAC-ANKRD26 fusion transcript.
Wahlster, L., Verboon, J.M., Ludwig, L.S., Black, S.C., Luo, W., Garg, K., Voit, R.A., Collins, R.L., Garimella, K., Costello, M., Chao, K.R., Goodrich, J.K., DiTroia, S.P., O’Donnell-Luria, A., Talkowski, M.E., Michelson, A.D., Cantor, A.B. and Sankaran, V.G.
Journal of Experimental Medicine 218 (6): e20210444. 7 June 2021

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V., Berruezo-Llacuna, M., Altwasser, R., Winkler, W., Sundaravinayagam, D., Balasubramanian, S., Caganova, M., Graf, R., Rahjouei, A., Henke, M.T., Driesner, M., Keller, L., Prigione, A., Janz, M., Akalin, A. and Di Virgilio, M.
Journal of Experimental Medicine 217 (10): e20200137. 5 October 2020

Restriction of memory B cell differentiation at the germinal center B cell positive selection stage.
Toboso-Navasa, A., Gunawan, A., Morlino, G., Nakagawa, R., Taddei, A., Damry, D., Patel, Y., Chakravarty, P., Janz, M., Kassiotis, G., Brink, R., Eilers, M. and Calado, D.P.
Journal of Experimental Medicine 217 (7): e20191933. 6 July 2020

Impaired human hematopoiesis due to a cryptic intronic splicing mutation.
Abdulhay, N.J., Fiorini, C., Verboon, J.M., Ludwig, L.S., Ulirsch, J.C., Zieger, B., Lareau, C.A., Mi, X., Roy, A., Obeng, E.A., Erlacher, M., Gupta, N., Gabriel, S.B., Ebert, B.L., Niemeyer, C.M., Khoriaty, R.N., Ancliff, P., Gazda, H.T., Wlodarski, M.W. and Sankaran, V.G.
Journal of Experimental Medicine 216 (5): 1050-1060. 6 May 2019

Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.
Basheer, F., Giotopoulos, G., Meduri, E., Yun, H., Mazan, M., Sasca, D., Gallipoli, P., Marando, L., Gozdecka, M., Asby, R., Sheppard, O., Dudek, M., Bullinger, L., Döhner, H., Dillon, R., Freeman, S., Ottmann, O., Burnett, A., Russell, N., Papaemmanuil, E., Hills, R., Campbell, P., Vassiliou, G.S.. and Huntly, B.J.P.
Journal of Experimental Medicine 216 (4): 966-981. 1 April 2019

Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities.
Serresi, M., Siteur, B., Hulsman, D., Company, C., Schmitt, M.J., Lieftink, C., Morris, B., Cesaroni, M., Proost, N., Beijersbergen, R.L., van Lohuizen, M. and Gargiulo, G.
Journal of Experimental Medicine 215 (12): 3115. 3 December 2018

B1a B cells require autophagy for metabolic homeostasis and self-renewal.
Clarke, A.J., Riffelmacher, T., Braas, D., Cornall, R.J. and Simon, A.K.
Journal of Experimental Medicine 215 (2): 399-413. 5 February 2018

SORLA attenuates EphA4 signaling and amyloid, β-induced neurodegeneration.
Huang, T.Y., Zhao, Y., Jiang, L.L., Li, X., Liu, Y., Sun, Y., Piña-Crespo, J.C., Zhu, B., Masliah, E., Willnow, T.E., Pasquale, E.B. and Xu, H.
Journal of Experimental Medicine 214 (12): 3669-3685. 4 December 2017

Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.
Chen, X., Poncette, L. and Blankenstein, T.
Journal of Experimental Medicine 214 (11): 3417-3433. 6 November 2017

Developmental origin and maintenance of distinct testicular macrophage populations.
Mossadegh-Keller, N., Gentek, R., Gimenez, G., Bigot, S., Mailfert, S. and Sieweke, M.H.
Journal of Experimental Medicine 214 (10): 2829-2841. 2 October 2017

Gene silencing and a novel monoallelic expression pattern in distinct CD177 neutrophil subsets.
Eulenberg-Gustavus, C., Bähring, S., Maass, P., Luft, F.C. and Kettritz, R.
Journal of Experimental Medicine 214 (7): 2089-2101. 3 July 2017

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.
Textor, A., Schmidt, K., Kloetzel, P.M., Weißbrich, B., Perez, C., Charo, J., Anders, K., Sidney, J., Sette, A., Schumacher, T.N.M., Keller, C., Busch, D.H., Seifert, U. and Blankenstein, T.
Journal of Experimental Medicine 213 (11): 2333-2348. 17 October 2016

M-CSF improves protection against bacterial and fungal infections after hematopoietic stem/progenitor cell transplantation.
Kandalla, P.K., Sarrazin, S., Molawi, K., Berruyer, C., Redelberger, D., Favel, A., Bordi, C., de Bentzmann, S. and Sieweke, M.H.
Journal of Experimental Medicine 213 (11): 2269-2279. 10 October 2016

Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4.
Uckelmann, H., Blaszkiewicz, S., Nicolae, C., Haas, S., Schnell, A., Wurzer, S., Wagener, R., Aszodi, A. and Essers, M.A.G.
Journal of Experimental Medicine 213 (10): 1961-1971. 19 September 2016

miR-23~27~24 clusters control effector T cell differentiation and function.
Cho, S., Wu, C.J., Yasuda, T., Cruz, L.O., Khan, A.A., Lin, L.L., Nguyen, D.T., Miller, M., Lee, H.M., Kuo, M.L., Broide, D.H., Rajewsky, K., Rudensky, A.Y. and Lu, L.F.
Journal of Experimental Medicine 213 (2): 235-249. 8 February 2016

Progressive replacement of embryo-derived cardiac macrophages with age.
Molawi, K., Wolf, Y., Kandalla, P.K., Favret, J., Hagemeyer, N., Frenzel, K., Pinto, A.R., Klapproth, K., Henri, S., Malissen, B., Rodewald, H.R., Rosenthal, N.A., Bajenoff, M., Prinz, M., Jung, S. and Sieweke, M.H.
Journal of Experimental Medicine 211 (11): 2151-2158. 20 October 2014

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.
Lancini, C., van den Berk, P.C.M., Vissers, J.H.A., Gargiulo, G., Song, J.Y., Hulsman, D., Serresi, M., Tanger, E., Blom, M., Vens, C., van Lohuizen, M., Jacobs, H. and Citterio, E.
Journal of Experimental Medicine 211 (9): 1759-1777. 25 August 2014

Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression.
Vaeth, M., Mueller, G., Stauss, D., Dietz, L., Klein-Hessling, S., Serfling, E., Lipp, M., Berberich, I. and Berberich-Siebelt, F.
Journal of Experimental Medicine 211 (3): 545-561. 10 March 2014

Cross talk between Wnt/β-catenin and Irf8 in leukemia progression and drug resistance.
Scheller, M., Schönheit, J., Zimmermann, K., Leser, U., Rosenbauer, F. and Leutz, A.
Journal of Experimental Medicine 210 (11): 2239-2256. 21 October 2013

Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes.
Kreslavsky, T., Kim, H.J., Koralov, S.B., Ghitza, D., Buch, T., Cantor, H., Rajewsky, K. and von Boehmer, H.
Journal of Experimental Medicine 210 (10): 1911-1918. 23 September 2013

Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis.
Soler, A., Serra, H., Pearce, W., Angulo, A., Guillermet-Guibert, J., Friedman, L.S., Viñals, F., Gerhardt, H., Casanovas, O., Graupera, M. and Vanhaesebroeck, B.
Journal of Experimental Medicine 210 (10): 1937-1945. 23 September 2013

Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis.
Augustin, I., Gross, J., Baumann, D., Korn, C., Kerr, G., Grigoryan, T., Mauch, C., Birchmeier, W. and Boutros, M.
Journal of Experimental Medicine 210 (9): 1761-1777. 26 August 2013

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
Kaji, T., Ishige, A., Hikida, M., Taka, J., Hijikata, A., Kubo, M., Nagashima, T., Takahashi, Y., Kurosaki, T., Okada, M., Ohara, O., Rajewsky, K. and Takemori, T.
Journal of Experimental Medicine 209 (11): 2079-2097. 22 October 2012

A role for GPx3 in activity of normal and leukemia stem cells.
Herault, O., Hope, K.J., Deneault, E., Mayotte, N., Chagraoui, J., Wilhelm, B.T., Cellot, S., Sauvageau, M., Andrade-Navarro, M.A., Hebert, J. and Sauvageau, G.
Journal of Experimental Medicine 209 (5): 895-901. 7 May 2012

Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
Steininger, A., Moebs, M., Ullmann, R., Koechert, K., Kreher, S., Lamprecht, B., Anagnostopoulos, I., Hummel, M., Richter, J., Beyer, M., Janz, M., Klemke, C.D., Stein, H., Doerken, B., Sterry, W., Schrock, E., Mathas, S. and Assaf, C.
Journal of Experimental Medicine 208 (8): 1585-1593. 1 August 2011

Platelet-derived serotonin links vascular disease and tissue fibrosis.
Dees, C., Akhmetshina, A., Zerr, P., Reich, N., Palumbo, K., Horn, A., Juengel, A., Beyer, C., Kroenke, G., Zwerina, J., Reiter, R., Alenina, N., Maroteaux, L., Gay, S., Schett, G., Distler, O. and Distler, J.H.
Journal of Experimental Medicine 208 (5): 961-972. 9 May 2011

CCR6 is expressed on an IL-10–producing, autoreactive memory T cell population with context-dependent regulatory function.
Rivino, L., Gruarin, P., Häringer, B., Steinfelder, S., Lozza, L., Steckel, B., Weick, A., Sugliano, E., Jarrossay, D., Kühl, A.A., Loddenkemper, C., Abrignani, S., Sallusto, F., Lanzavecchia, A. and Geginat, J.
Journal of Experimental Medicine 207 (3): 565-577. 15 March 2010

NOD2 regulates hematopoietic cell function during graft-versus-host disease.
Penack, O., Smith, O.M., Cunningham-Bussel, A., Liu, X., Rao, U., Yim, N., Na, I.K., Holland, A.M., Ghosh, A., Lu, S.X., Jenq, R.R., Liu, C., Murphy, G.F., Brandl, K. and van den Brink, M.R.M.
Journal of Experimental Medicine 206 (10): 2101-2110. 28 September 2009

The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1).
Steinfelder, S., Andersen, J.F., Cannons, J.L., Feng, C.G., Joshi, M., Dwyer, D., Caspar, P., Schwartzberg, P.L., Sher, A. and Jankovic, D.
Journal of Experimental Medicine 206 (8): 1681-1690. 3 August 2009

The tight junction protein CAR regulates cardiac conduction and cell-cell communication.
Lisewski, U., Shi, Y., Wrackmeyer, U., Fischer, R., Chen, C., Schirdewan, A., Juettner, R., Rathjen, F.G., Poller, W., Radke, M.H. and Gotthardt, M.
Journal of Experimental Medicine 205 (10): 2369-2379. 29 September 2008

Autoregulation of Th1-mediated inflammation by twist1.
Niesner, U., Albrecht, I., Janke, M., Doebis, C., Loddenkemper, C., Lexberg, M.H., Eulenburg, K., Kreher, S., Koeck, J., Baumgrass, R., Bonhagen, K., Kamradt, T., Enghard, P., Humrich, J.Y., Rutz, S., Schulze-Topphoff, U., Aktas, O., Bartfeld, S., Radbruch, H., Hegazy, A.N., Lohning, M., Baumgart, D.C., Duchmann, R., Rudwaleit, M., Haupl, T., Gitelman, I., Krenn, V., Gruen, J., Sieper, J., Zeitz, M., Wiedenmann, B., Zipp, F., Hamann, A., Janitz, M., Scheffold, A., Burmester, G.R., Chang, H.D. and Radbruch, A.
Journal of Experimental Medicine 205 (8): 1889-1901. 4 August 2008

Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness.
Willimsky, G., Czeh, M., Loddenkemper, C., Gellermann, J., Schmidt, K., Wust, P., Stein, H. and Blankenstein, T.
Journal of Experimental Medicine 205 (7): 1687-1700. 7 July 2008

Antiribosomal-P autoantibodies from psychiatric lupus target a novel neuronal surface protein causing calcium influx and apoptosis.
Matus, S., Burgos, P.V., Bravo-Zehnder, M., Kraft, R., Porras, O.H., Farias, P., Barros, L.F., Torrealba, F., Massardo, L., Jacobelli, S. and Gonzalez, A.
Journal of Experimental Medicine 204 (13): 3221-3234. 24 December 2007

Cryoelectron tomography reveals periodic material at the inner side of subpellicular microtubules in apicomplexan parasites.
Cyrklaff, M., Kudryashev, M., Leis, A., Leonard, K., Baumeister, W., Menard, R., Meissner, M. and Frischknecht, F.
Journal of Experimental Medicine 204 (6): 1281-1287. 11 June 2007

CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells.
Schneider, M.A., Meingassner, J.G., Lipp, M., Moore, H.D. and Rot, A.
Journal of Experimental Medicine 204 (4): 735-745. 16 April 2007

Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells.
Rössig, L., Urbich, C., Brühl, T., Dernbach, E., Heeschen, C., Chavakis, E., Sasaki, K.I., Aicher, D., Diehl, F., Seeger, F., Potente, M., Aicher, A., Zanetta, L., Dejana, E., Zeiher, A.M. and Dimmeler, S.
Journal of Experimental Medicine 201 (11): 1825-35. 6 June 2005

Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection.
Kursar, M., Höpken, U.E., Koch, M., Koehler, A., Lipp, M., Kaufmann, S.H. and Mittrücker, H.W.
Journal of Experimental Medicine 201 (9): 1447-1457. 2 May 2005

CCR7 signals are essential for cortex-medulla migration of developing thymocytes.
Ueno, T., Saito, F., Gray, D.H.D., Kuse, S., Hieshima, K., Nakano, H., Kakiuchi, T., Lipp, M., Boyd, R.L. and Takahama, Y.
Journal of Experimental Medicine 200 (4): 493-505. 16 August 2004

c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.
Mathas, S., Lietz, A., Anagnostopoulos, I., Hummel, F., Wiesner, B., Janz, M., Jundt, F., Hirsch, B., Joehrens-Leder, K., Vornlocher, H.P., Bommert, K., Stein, H. and Doerken, B.
Journal of Experimental Medicine 199 (8): 1041-1052. 19 April 2004

Tumor rejection by modulation of tumor stromal fibroblasts.
Schueler, T., Koernig, S. and Blankenstein, T.
Journal of Experimental Medicine 198 (10): 1487-1493. 17 November 2003

Regulation of dendritic cell migration to the draining lymph node: Impact on T lymphocyte traffic and priming.
Martin-Fontecha, A., Sebastiani, S., Höpken, U.E., Uguccioni, M., Lipp, M., Lanzavecchia, A. and Sallusto, F.
Journal of Experimental Medicine 198 (4): 615-621. 18 August 2003

Differentiation of effector/memory V ae 2 T cells and migratory routes in lymph nodes or inflammatory sites.
Dieli, F., Poccia, F., Lipp, M., Sireci, G., Caccamo, N., Di Sano, C. and Salerno, A.
Journal of Experimental Medicine 198 (3): 391-397. 4 August 2003

Cooperating mechanisms of CXCR5 and CCR7 in development and organization of secondary lymphoid organs.
Ohl, L., Henning, G., Krautwald, S., Lipp, M., Hardtke, S., Bernhardt, G., Pabst, O. and Foerster, R.
Journal of Experimental Medicine 197 (9): 1199-1204. 5 May 2003

Treatment of relapsing paralysis in experimental encephalomyelitis by targeting Th1 cells through atorvastatin.
Aktas, O., Waiczies, S., Smorodchenko, A., Dorr, J., Seeger, B., Prozorovski, T., Sallach, S., Endres, M., Brocke, S., Nitsch, R. and Zipp, F.
Journal of Experimental Medicine 197 (6): 725-733. 17 March 2003

Nucleolin as activator of human papillomavirus type 18 oncogene transcription in cervical cancer.
Grinstein, E., Wernet, P., Snijders, P.J.F., Rosl, F., Weinert, I., Jia, W.T., Kraft, R., Schewe, C., Schwabe, M., Hauptmann, S., Dietel, M., Meijer, C.J.L.M. and Royer, H.D.
Journal of Experimental Medicine 196 (8): 1067-1078. 21 October 2002

Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
Hinz, M., Lemke, P., Anagnostopoulos, I., Hacker, C., Krappmann, D., Mathas, S., Doerken, B., Zenke, M., Stein, H. and Scheidereit, C.
Journal of Experimental Medicine 196 (5): 605-617. 2 September 2002

Chemokine requirements for B cell entry to lymph nodes and Peyers patches.
Okada, T., Ngo, V.N., Ekland, E.H., Foerster, R., Lipp, M., Littman, D.R. and Cyster, J.G.
Journal of Experimental Medicine 196 (1): 65-75. 1 July 2002

Inhibition of methylcholanthrene-induced carcinogenesis by an interferon gamma receptor-dependent foreign body reaction.
Qin, Z., Kim, H.J., Hemme, J. and Blankenstein, T.
Journal of Experimental Medicine 195 (11): 1479-1490. 3 June 2002

CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: Modulation by FTY720.
Henning, G., Ohl, H., Junt, T., Reiterer, P., Brinkmann, V., Nakano, H., Hohenberger, W., Lipp, M. and Foerster, R.
Journal of Experimental Medicine 194 (12): 1875-1881. 17 December 2001

Generation of tumor-associated cytotoxic T lymphocytes requires interleukin 4 from CD8+ T cells.
Schueler, T., Kammertoens, T., Preiss, S., Debs, P., Noben-Trauth, N. and Blankenstein, T.
Journal of Experimental Medicine 194 (12): 1767-1775. 17 December 2001

Tumor rejection by disturbing tumor stroma cell interactions.
Ibe, S., Qin, Z.H., Schueler, T., Preiss, S. and Blankenstein, T.
Journal of Experimental Medicine 194 (11): 1549-1559. 3 December 2001

Aberrant high expression of B lymphocyte chemokine (BLC/CXCL13) by C11b+CD11c+ dendritic cells in murine lupus and preferential chemotaxis of B1 cells towards BLC.
Ishikawa, S., Sato, T., Abe, M., Nagai, S., Onai, N., Yoneyama, H., Zhang, Y.Y., Suzuki, T., Hashimoto, S., Shirai, T., Lipp, M. and Matsushima, K.
Journal of Experimental Medicine 193 (12): 1393-1402. 18 June 2001

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production.
Breitfeld, D., Ohl, L., Kremmer, E., Ellwart, J., Sallusto, F., Lipp, M. and Foerster, R.
Journal of Experimental Medicine 192 (11): 1545-1551. 4 December 2000

CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function.
Schaerli, P., Willimann, K., Lang, A.B., Lipp, M., Loetscher, P. and Moser, B.
Journal of Experimental Medicine 192 (11): 1553-1562. 4 December 2000

Suppression of tumorigenicity in breast cancer cells by the microfilament protein profilin 1.
Janke, J., Schlueter, K., Jandrig, B., Theile, M., Koelble, K., Arnold, W., Grinstein, E., Schwartz, A., Estevez-Schwarz, L., Schlag, P.M., Jockusch, B.M. and Scherneck, S.
Journal of Experimental Medicine 191 (10): 1675-1685. 15 May 2000

Induction and suppression of an autoimmune disease by oligomerized T cell epitopes: enhanced in vivo potency of encephalitogenic peptides.
Falk, K., Roetzschke, O., Santambrogio, L., Dorf, M.E., Brosnan, C. and Strominger, J.L.
Journal of Experimental Medicine 191 (4): 717-730. 21 February 2000

Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.
Walker, L.S.K., Gulbranson-Judge, A., Flynn, S., Brocker, T., Raykundalia, C., Goodall, M., Foerster, R., Lipp, M. and Lane, P.
Journal of Experimental Medicine 190 (8): 1115-1122. 18 October 1999

T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice.
Schueler, T., Qin, Z., Ibe, S., Noben-Trauth, N. and Blankenstein, T.
Journal of Experimental Medicine 189 (5): 803-810. 1 March 1999

Interleukin 4 gene-defective mice reconstituted with wild-type bone marrow fail to produce normal immunoglobulin E levels.
Lange, C., Schueler, T. and Blankenstein, T.
Journal of Experimental Medicine 187 (9): 1487-1493. 4 May 1998

Impaired inflammatory responses in the reverse arthus reaction through genetic deletion of the C5a receptor.
Höpken, U.E., Lu, B., Gerard, N.P. and Gerard, C.
Journal of Experimental Medicine 186 (5): 749-756. 29 August 1997

Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse.
Morawetz, R.A., Gabriele, L., Rizzo, L.V., Noben-Trauth, N., Kühn, R., Rajewsky, K., Müller, W., Doherty, T.M., Finkelman, F., Coffman, R.L. and Morse, H.C.
Journal of Experimental Medicine 184 (5): 1651-1661. 1 November 1996

Proteasome alpha-type subunit C9 is a primary target of autoantibodies in sera of patients with myositis and systemic lupus erythematosus.
Feist, E., Doerner, T., Kuckelkorn, U., Schmidtke, G., Micheel, B., Hiepe, F., Burmester, G.R. and Kloetzel, P.M.
Journal of Experimental Medicine 184 (4): 1313-1318. 1 October 1996

Remnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes.
Sinnis, P., Willnow, T.E., Briones, M.R., Herz, J. and Nussenzweig, V.
Journal of Experimental Medicine 184 (3): 945-954. 1 September 1996

T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.
Davidson, N.J., Leach, M.W., Fort, M.M., Thompson-Snipes, L., Kühn, R., Müller, W., Berg, D.J. and Rennick, D.M.
Journal of Experimental Medicine 184 (1): 241-251. 1 July 1996

Blocking of transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in scid mice.
Bargou, R.C., Wagener, C., Bommert, K., Arnold, W., Daniel, P.T., Mapara, M.Y., Grinstein, E., Royer, H.D. and Doerken, B.
Journal of Experimental Medicine 183 (3): 1205-1213. 1 March 1996

Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice.
Carrera, L., Gazzinelli, R.T., Badolato, R., Hieny, S., Mueller, W., Kühn, R. and Sacks, D.L.
Journal of Experimental Medicine 183 (2): 515-526. 1 February 1996

Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses.
Berg, D.J., Leach, M.W., Kühn, R., Rajewsky, K., Müller, W., Davidson, N.J. and Rennick, D.
Journal of Experimental Medicine 182 (1): 99-108. 1 July 1995

Molecular mimicry between the immunodominant ribosomal protein PO of Trypanosoma cruzi and a functional epitope on the human beta1-adrenergic receptor.
Ferrari, I., Levin, M.J., Wallukat, G., Elies, R., Lebesgue, D., Chiale, P., Elizari, M., Rosenbaum, M. and Hoebeke, J.
Journal of Experimental Medicine 182 (1): 59-65. 1 July 1995

Expression of tumor necrosis factor by different tumor cell lines results either in tumor suppression or augmented metastasis.
Qin, Z., Krueger-Krasagakes, S., Kunzendorf, U., Hock, H., Diamantstein, T. and Blankenstein, T.
Journal of Experimental Medicine 178 (1): 355-360. 1 July 1993

Characterization of a novel Hodgkin cell-line, HD-MyZ, HD-Myr, with myelomonocytic features mimicking Hodgkin's disease in severe combined immunodeficient mice.
Bargou, R.C., Mapara, M.Y., Zugck, C., Daniel, P.T., Pawlita, M., Doehner, H. and Doerken, B.
Journal of Experimental Medicine 177 (5): 1257-1268. 1 May 1993

Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.
Breit, T.M., Mol, E.J., Wolvers-Tettero, I.L., Ludwig, W.D., van Wering, E.R. and van Dongen, J.J.
Journal of Experimental Medicine 177 (4): 965-977. 1 April 1993

Review

Cellular senescence: Neither irreversible nor reversible.
Reimann, M., Lee, S. and Schmitt, C.A.
Journal of Experimental Medicine 221 (4): e20232136. 1 April 2024

Comment

Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells.
Schmitz, J., Thiel, A., Kühn, R., Rajewsky, K., Müller, W., Assenmacher, M. and Radbruch, A.
Journal of Experimental Medicine 179 (4): 1349-53. 1 April 1994