Browse by Journal Title

2024

Abnormal biomarkers predict complex FAS or FADD defects missed by exome sequencing.
Rensing-Ehl, A., Lorenz, M.R., Führer, M., Willenbacher, W., Willenbacher, E., Sopper, S., Abinun, M., Maccari, M.E., König, C., Haegele, P., Fuchs, S., Castro, C., Kury, P., Pelle, O., Klemann, C., Heeg, M., Thalhammer, J., Wegehaupt, O., Fischer, M., Goldacker, S., Schulte, B., Biskup, S., Chatelain, P., Schuster, V., Warnatz, K., Grimbacher, B., Meinhardt, A., Holzinger, D., Oommen, P.T., Hinze, T., Hebart, H., Seeger, K., Lehmberg, K., Leahy, T.R., Claviez, A., Vieth, S., Schilling, F.H., Fuchs, I., Groß, M., Rieux-Laucat, F., Magerus, A., Speckmann, C., Schwarz, K. and Ehl, S.
Journal of Allergy and Clinical Immunology 153 (1): 297-308. January 2024

2022

Filaggrin loss-of-function mutations are associated with persistence of egg and milk allergy.
Kalb, B., Marenholz, I., Jeanrenaud, A.C.S.N., Meixner, L., Arnau-Soler, A., Rosillo-Salazar, O.D., Ghauri, A., Cibin, P., Blümchen, K., Schlags, R., Hansen, G., Seidenberg, J., Keil, T., Lau, S., Niggemann, B., Beyer, K. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 150 (5): 1125-1134. November 2022

2021

Regulating T-cell differentiation through the polyamine spermidine.
Carriche, G.M., Almeida, L., Stüve, P., Velasquez, L., Dhillon-LaBrooy, A., Roy, U., Lindenberg, M., Strowig, T., Plaza-Sirvent, C., Schmitz, I., Lochner, M., Simon, A.K. and Sparwasser, T.
Journal of Allergy and Clinical Immunology 147 (1): 335-348. January 2021

2020

Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression.
Mucha, S., Baurecht, H., Novak, N., Rodríguez, E., Bej, S., Mayr, G., Emmert, H., Stölzl, D., Gerdes, S., Degenhardt, F., Hübenthal, M., Ellinghaus, E., Jung, E.S., Kässens, J.C., Wienbrandt, L., Lieb, W., Müller-Nurasyid, M., Hotze, M., Dand, N., Grosche, S., Marenholz, I., Arnold, A., Homuth, G., Schmidt, C.O., Wehkamp, U., Nöthen, M.M., Hoffmann, P., Paternoster, L., Standl, M., Bønnelykke, K., Ahluwalia, T.S., Bisgaard, H., Peters, A., Gieger, C., Waldenberger, M., Schulz, H., Strauch, K., Werfel, T., Lee, Y.A., Wolfien, M., Rosenstiel, P., Wolkenhauer, O., Schreiber, St., Franke, A., Weidinger, S. and Ellinghaus, D.
Journal of Allergy and Clinical Immunology 145 (4): 1208-1218. April 2020

2019

Eleven loci with new reproducible genetic associations with allergic disease risk.
Ferreira, M.A., Vonk, J.M., Baurecht, H., Marenholz, I., Tian, C., Hoffman, J.D., Helmer, Q., Tillander, A., Ullemar, V., Lu, Y., Rüschendorf, F., Hinds, D.A., Hübner, N., Weidinger, S., Magnusson, P.K., Jorgenson, E., Lee, Y.A., Boomsma, D.I., Karlsson, R., Almqvist, C., Koppelman, G.H. and Paternoster, L.
Journal of Allergy and Clinical Immunology 143 (2): 691-699. February 2019

2018

Mutations affecting the actin regulator WD repeat-containing protein 1 lead to aberrant lymphoid immunity.
Pfajfer, L., Mair, N.K, Jiménez-Heredia, R., Genel, F., Gulez, N., Ardeniz, Ö., Hoeger, B., Bal, S.K., Madritsch, C., Kalinichenko, A., Chandra Ardy, R., Gerçeker, B., Rey-Barroso, J., Ijspeert, H., Tangye, S.G., Simonitsch-Klupp, I., Huppa, J.B., van der Burg, M., Dupré, L. and Boztug, K.
Journal of Allergy and Clinical Immunology 142 (5): 1589-1604.e11. November 2018

Evaluation of food allergy candidate loci in the Genetics of Food Allergy Study.
Marenholz, I., Grosche, S., Rüschendorf, F., Kalb, B., Blumchen, K., Schlags, R., Harandi, N., Price, M., Hansen, G., Seidenberg, J., Yürek, S., Homuth, G., Schmidt, C.O., Nöthen, M.M., Hubner, N., Niggemann, B., Beyer, K. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 142 (4): 1368-1370. October 2018

A comparative analysis of human bone marrow-resident and peripheral memory B cells.
Becker, S.C., Szyska, M., Mensen, A., Hellwig, K., Otto, R., Olfe, L., Volk, H.D., Dörner, T., Dörken, B., Scheibenbogen, C., Schröder, J., Hocke, A.C. and Na, I.K.
Journal of Allergy and Clinical Immunology 141 (5): 1911-1913. May 2018

A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma.
Asai, Y., Eslami, A., van Ginkel, C.D., Akhabir, L., Wan, M., Yin, D., Ellis, G., Ben-Shoshan, M., Marenholz, I., Martino, D., Ferreira, M.A., Allen, K., Mazer, B., de Groot, H., de Jong, N.W., Gerth van Wijk, R., Dubois, A.E.J., Grosche, S., Ashley, S., Rüschendorf, F., Kalb, B., Beyer, K., Nöthen, M.M., Lee, Y.A., Chin, R., Cheuk, S., Hoffman, J., Jorgensen, E., Witte, J.S., Melles, R.B., Hong, X., Wang, X., Hui, J., Musk, A.W.B., Hunter, M., James, A.L., Koppelman, G.H., Sandford, A.J., Clarke, A.E. and Daley, D.
Journal of Allergy and Clinical Immunology 141 (4): 1513-1516. April 2018

2016

DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis.
Sarnowski, C., Laprise, C., Malerba, G., Moffatt, M.F., Dizier, M.H., Morin, A., Vincent, Q.B., Rohde, K., Esparza-Gordillo, J., Margaritte-Jeannin, P., Liang, L., Lee, Y.A., Bousquet, J., Siroux, V., Pignatti, P.F., Cookson, W.O., Lathrop, M., Pastinen, T., Demenais, F. and Bouzigon, E.
Journal of Allergy and Clinical Immunology 138 (3): 748-753. September 2016

Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes.
Schmitt, J., Schwarz, K., Baurecht, H., Hotze, M., Fölster-Holst, R., Rodríguez, E., Lee, Y.A.E., Franke, A., Degenhardt, F., Lieb, W., Gieger, C., Kabesch, M., Nöthen, M.M., Irvine, A.D., McLean, W.H.I., Deckert, S., Stephan, V., Schwarz, P., Aringer, M., Novak, N. and Weidinger, S.
Journal of Allergy and Clinical Immunology 137 (1): 130-136. January 2016

2015

Prediction and prevention of allergic rhinitis: A birth cohort study of 20 years.
Grabenhenrich, L.B., Keil, T., Reich, A., Gough, H., Beschorner, J., Hoffmann, U., Bauer, C.P., Forster, J., Schuster, A., Schramm, D., Nitsche, O., Zepp, F., Lee, Y.A., Bergmann, R., Bergmann, K., Wahn, U. and Lau, S.
Journal of Allergy and Clinical Immunology 136 (4): 932-940. October 2015

A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis.
Schaarschmidt, H., Ellinghaus, D., Rodríguez, E., Kretschmer, A., Baurecht, H., Lipinski, S., Meyer-Hoffert, U., Harder, J., Lieb, W., Novak, N., Fölster-Holst, R., Esparza-Gordillo, J., Marenholz, I., Ruschendorf, F., Hubner, N., Reischl, E., Waldenberger, M., Gieger, C., Illig, T., Kabesch, M., Zhang, X.J., Xiao, F.L., Lee, Y.A., Franke, A. and Weidinger, S.
Journal of Allergy and Clinical Immunology 136 (3): 802-806. September 2015

An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex.
Kracker, S., Di Virgilio, M., Schwartzentruber, J., Cuenin, C., Forveille, M., Deau, M.C., McBride, K.M., Majewski, J., Gazumyan, A., Seneviratne, S., Grimbacher, B., Kutukculer, N., Herceg, Z., Cavazzana, M., Jabado, N., Nussenzweig, M.C., Fischer, A. and Durandy, A.
Journal of Allergy and Clinical Immunology 135 (4): 998-1007. April 2015

2014

Dry roasting enhances peanut-induced allergic sensitization across mucosal and cutaneous routes in mice.
Moghaddam, A.E., Hillson, W.R., Noti, M., Gartlan, K.H., Johnson, S., Thomas, B., Artis, D. and Sattentau, Q.J.
Journal of Allergy and Clinical Immunology 134 (6): 1453-1456. December 2014

A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency.
Pieper, K., Rizzi, M., Speletas, M., Smulski, C.R., Sic, H., Kraus, H., Salzer, U., Fiala, G.J., Schamel, W.W., Lougaris, V., Plebani, A., Hammarstrom, L., Recher, M., Germenis, A.E., Grimbacher, B., Warnatz, K., Rolink, A.G., Schneider, P., Notarangelo, L.D. and Eibel, H.
Journal of Allergy and Clinical Immunology 133 (4): 1222-1225. April 2014

Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure.
Scholtens, S., Postma, D.S., Moffatt, M.F., Panasevich, S., Granell, R., Henderson, A.J., Melen, E., Nyberg, F., Pershagen, G., Jarvis, D., Ramasamy, A., Wjst, M., Svanes, C., Bouzigon, E., Demenais, F., Kauffmann, F., Siroux, V., von Mutius, E., Ege, M.J., Braun-Fahrlaender, C., Genuneit, J., Brunekreef, B., Smit, H.A., Wijga, A.H., Kerkhof, M., Curjuric, I., Imboden, M., Thun, G.A., Probst-Hensch, N., Freidin, M.B., Bragina, E.I., Deev, I.A., Puzyrev, V.P., Daley, D., Park, J., Becker, A., Chan-Yeung, M., Kozyrskyj, A.L., Pare, P., Marenholz, I., Lau, S., Keil, T., Lee, Y.A., Kabesch, M., Wijmenga, C., Franke, L., Nolte, I.M., Vonk, J., Kumar, A., Farrall, M., Cookson, W.O.C.M., Strachan, D.P., Koppelman, G.H. and Boezen, H.M.
Journal of Allergy and Clinical Immunology 133 (3): 885-888. March 2014

2013

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.
Saunders, S.P., Goh, C.S.M., Brown, S.J., Palmer, C.N.A., Porter, R.M., Cole, C., Campbell, L.E., Gierlinski, M., Barton, G.J., Schneider, G., Balmain, A., Prescott, A.R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y.A., Tavendale, R., Mukhopadhyay, S., Turner, S.W., Madhok, V.B., Sullivan, F.M., Relton, C., Burn, J., Meggitt, S., Smith, C.H., Allen, M.A., Barker, J.N.W.N., Reynolds, N.J., Cordell, H.J., Irvine, A.D., McLean, W.H.I., Sandilands, A. and Fallon, P.G.
Journal of Allergy and Clinical Immunology 132 (5): 1121-1129. November 2013

A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis.
Esparza-Gordillo, J., Schaarschmidt, H., Liang, L., Cookson, W., Bauerfeind, A., Lee-Kirsch, M.A., Nemat, K., Henderson, J., Paternoster, L., Harper, J.L., Mangold, E., Nothen, M.M., Rüschendorf, F., Kerscher, T., Marenholz, I., Matanovic, A., Lau, S., Keil, T., Bauer, C.P., Kurek, M., Ciechanowicz, A., Macek, M., Franke, A., Kabesch, M., Hubner, N., Abecasis, G., Weidinger, S., Moffatt, M. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 132 (2): 371-377. August 2013

B-cell biology and development.
Pieper, K., Grimbacher, B. and Eibel, H.
Journal of Allergy and Clinical Immunology 131 (4): 959-971. April 2013

2012

The ANO3/MUC15 locus is associated with eczema in families ascertained through asthma.
Dizier, M.H., Margaritte-Jeannin, P., Madore, A.M., Esparza-Gordillo, J., Moffatt, M.F., Corda, E., Monier, F., Guilloud-Bataille, M., Franke, A., Weidinger, S., Annesi-Maesano, I., Just, J., Pin, I., Kauffmann, F., Cookson, W., Lee, Y.A., Laprise, C., Lathrop, M., Bouzigon, E. and Demenais, F.
Journal of Allergy and Clinical Immunology 129 (6): 1547-1553. June 2012

Genome-wide association study of lung function decline in adults with and without asthma.
Imboden, M., Bouzigon, E., Curjuric, I., Ramasamy, A., Kumar, A., Hancock, D.B., Wilk, J.B., Vonk, J.M., Thun, G.A., Siroux, V., Nadif, R., Monier, F., Gonzalez, J.R., Wjst, M., Heinrich, J., Loehr, L.R., Franceschini, N., North, K.E., Altmüller, J., Koppelman, G.H., Guerra, S., Kronenberg, F., Lathrop, M., Moffatt, M.F., O'Connor, G.T., Strachan, D.P., Postma, D.S., London, S.J., Schindler, C., Kogevinas, M., Kauffmann, Fr., Jarvis, D.L., Demenais, F. and Probst-Hensch, N.M.
Journal of Allergy and Clinical Immunology 129 (5): 1218-28. May 2012

2009

An interaction between filaggrin mutations and early food sensitization improves the prediction of childhood asthma.
Marenholz, I., Kerscher, T., Bauerfeind, A., Esparza-Gordillo, J., Nickel, R., Keil, T., Lau, S., Rohde, K., Wahn, U. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 123 (4): 911-916. April 2009

2007

Neuroimmune crosstalk in asthma: dual role of the neurotrophin receptor p75NTR.
Nassenstein, C., Kammertoens, T., Veres, T.Z., Uckert, W., Spies, E., Fuchs, B., Krug, N. and Braun, A.
Journal of Allergy and Clinical Immunology 120 (5): 1089-1096. November 2007

A common haplotype of the IL-31 gene influencing gene expression is associated with nonatopic eczema.
Schulz, F., Marenholz, I., Foelster-Holst, R., Chen, C., Sternjak, A., Baumgrass, R., Esparza-Gordillo, J., Grueber, C., Nickel, R., Schreiber, S., Stoll, M., Kurek, M., Rueschendorf, F., Huebner, N., Wahn, U. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 120 (5): 1097-1102. November 2007

2006

Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.
Marenholz, I., Nickel, R., Rueschendorf, F., Schulz, F., Esparza-Gordillo, J., Kerscher, T., Grueber, C., Lau, S., Worm, M., Keil, T., Kurek, M., Zaluga, E., Wahn, U. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 118 (4): 866-871. October 2006

2005

Lack of association of the G protein-coupled receptor for asthma susceptibility gene with atopic dermatitis.
Soederhaell, C., Marenholz, I., Nickel, R., Grueber, C., Kehrt, R., Rohde, K., Griffioen, R.W., Meglio, P., Tarani, L., Gustafsson, D., Hoffmann, U., Gerstner, B., Mueller, S., Wahn, U. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 116 (1): 220-221. 1 January 2005

2000

A European study on the genetics of mite sensitization.
Kurz, T., Strauch, K., Heinzmann, A., Braun, S., Jung, M., Rueschendorf, F., Moffatt, M.F., Cookson, W.O.C.M., Inacio, F., Ruffilli, A., Nordskov-Hansen, G., Peltre, G., Forster, J., Kuehr, J., Reis, A., Wienker, T.F. and Deichmann, K.A.
Journal of Allergy and Clinical Immunology 106 (5): 925-932. 1 January 2000

1991

Autoantibodies to beta2-adrenergic receptors with antiadrenergic activity from patients with allergic asthma.
Wallukat, G. and Wollenberger, A.
Journal of Allergy and Clinical Immunology 88 : 581-587. 1 January 1991