Browse by Journal Title

2024

Expression of mGluR5 in pediatric Hodgkin and Non-Hodgkin lymphoma-a comparative analysis of immunohistochemical and clinical findings regarding the association between tumor and paraneoplastic neurological disease.
Viezens, I., Knierim, E., Deubzer, H.E., Hauptmann, K., Fassbender, J., Morales-Gonzalez, S., Kaindl, A.M., Schuelke, M. and Nikolaus, M.
Cancers 16 (13): 2452. 4 July 2024

L-glyceraldehyde inhibits neuroblastoma cell growth via a multi-modal mechanism on metabolism and Signaling.
Forbes, M., Kempa, R., Mastrobuoni, G., Rayman, L., Pietzke, M., Bayram, S., Arlt, B., Spruessel, A., Deubzer, H.E. and Kempa, S.
Cancers 16 (9): 1664. May 2024

Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies.
Torke, S., Walther, W. and Stein, U.
Cancers 16 (7): 1330. 28 March 2024

MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer.
Erdem, M., Lee, K.H., Hardt, M., Regan, J.L., Kobelt, D., Walther, W., Mokrizkij, M., Regenbrecht, C. and Stein, U.
Cancers 16 (3): 604. 31 January 2024

2023

Establishment and thorough characterization of xenograft (PDX) models derived from patients with pancreatic cancer for molecular analyses and chemosensitivity testing.
Behrens, D., Pfohl, U., Conrad, T., Becker, M., Brzezicha, B., Büttner, B., Wagner, S., Hallas, C., Lawlor, R., Khazak, V., Linnebacher, M., Wartmann, T., Fichtner, I., Hoffmann, J., Dahlmann, M. and Walther, W.
Cancers 15 (24): 5753. 8 December 2023

Mechanisms of resistance to small molecules in acute myeloid leukemia.
Lang, T.J.L., Damm, F., Bullinger, L. and Frick, M.
Cancers 15 (18): 4573. 15 September 2023

Metastasis associated in colorectal cancer 1 (MACC1) mRNA expression is enhanced in sporadic vestibular schwannoma and correlates to deafness.
Breun, M., Flock, K., Feldheim, J., Nattmann, A., Monoranu, C.M., Herrmann, P., Ernestus, R.I., Löhr, M., Hagemann, C. and Stein, U.
Cancers 15 (16): 4089. 14 August 2023

Advanced radio frequency applicators for thermal magnetic resonance theranostics of brain tumors.
Saha, N., Kuehne, A., Millward, J.M., Eigentler, T.W., Starke, L., Waiczies, S. and Niendorf, T.
Cancers 15 (8): 2303. 14 April 2023

2022

Multi-omics alleviates the limitations of panel sequencing for cancer drug response prediction.
Baranovskii, A., Gündüz, I.B., Franke, V., Uyar, B. and Akalin, A.
Cancers 14 (22): 5604. 15 November 2022

Pre-diagnostic circulating resistin concentrations are not associated with colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study.
Pham, T.T., Nimptsch, K., Aleksandrova, K., Jenab, M., Reichmann, R., Wu, K., Tjønneland, A., Kyrø, C., Schulze, M.B., Kaaks, R., Katzke, V., Palli, D., Pasanisi, F., Ricceri, F., Tumino, R., Krogh, V., Roodhart, J., Castilla, J., Sánchez, M.J., Colorado-Yohar, S.M., Harbs, J., Rutegård, M., Papier, K., Aglago, E.K., Dimou, N., Mayen-Chacon, A.L., Weiderpass, E. and Pischon, T.
Cancers 14 (22): 5499. 9 November 2022

The monocyte, a maestro in the tumor microenvironment (TME) of breast cancer.
Amer, H.T., Stein, U. and El Tayebi, H.M.
Cancers 14 (21): 5460. 7 November 2022

Radiofrequency electromagnetic fields cause non-temperature-induced physical and biological effects in cancer cells.
Wust, P., Veltsista, P.D., Oberacker, E., Yavvari, P., Walther, W., Bengtsson, O., Sterner-Kock, A., Weinhart, M., Heyd, F., Grabowski, P., Stintzing, S., Heinrich, W., Stein, U. and Ghadjar, P.
Cancers 14 (21): 5349. 30 October 2022

Concomitant cytotoxic effector differentiation of CD4(+) and CD8(+) T cells in response to EBV-Infected B cells.
Tamura, Y., Yamane, K., Kawano, Y., Bullinger, L., Wirtz, T., Weber, T., Sander, S., Ohki, S., Kitajima, Y., Okada, S., Rajewsky, K. and Yasuda, T.
Cancers 14 (17): 4118. 25 August 2022

Core-clock genes regulate proliferation and invasion via a reciprocal interplay with MACC1 in colorectal cancer cells.
Basti, A., Malhan, D., Dumbani, M., Dahlmann, M., Stein, U. and Relógio, A.
Cancers 14 (14): 3458. 16 July 2022

Uncovering the contribution of moderate-penetrance susceptibility genes to breast cancer by whole-exome sequencing and targeted enrichment sequencing of candidate genes in women of European ancestry.
Dumont, M., Weber-Lassalle, N., Joly-Beauparlant, C., Ernst, C., Droit, A., Feng, B.J., Dubois, S., Collin-Deschesnes, A.C., Soucy, P., Vallée, M., Fournier, F., Lemaçon, A., Adank, M.A., Allen, J., Altmüller, J., Arnold, N., Ausems, M.G.E.M., Berutti, R., Bolla, M.K., Bull, S., Carvalho, S., Cornelissen, S., Dufault, M.R., Dunning, A.M., Engel, C., Gehrig, A., Geurts-Giele, W.R.R., Gieger, C., Green, J., Hackmann, K., Helmy, M., Hentschel, J., Hogervorst, F.B.L., Hollestelle, A., Hooning, M.J., Horváth, J., Ikram, M.A., Kaulfuß, S., Keeman, R., Kuang, D., Luccarini, C., Maier, W., Martens, J.W.M., Niederacher, D., Nürnberg, P., Ott, C.E., Peters, A., Pharoah, P.D.P., Ramirez, A., Ramser, J., Riedel-Heller, S., Schmidt, G., Shah, M., Scherer, M., Stäbler, A., Strom, T.M., Sutter, C., Thiele, H., van Asperen, C.J., van der Kolk, L., van der Luijt, R.B., Volk, A.E., Wagner, M., Waisfisz, Q., Wang, Q., Wang-Gohrke, S., Weber, B.H.F., Devilee, P., Tavtigian, S., Bader, G.D., Meindl, A., Goldgar, D.E., Andrulis, I.L., Schmutzler, R.K., Easton, D.F., Schmidt, M.K., Hahnen, E. and Simard, J.
Cancers 14 (14): 3363. 11 July 2022

Prevalence of cancer predisposition germline variants in male breast cancer patients: results of the German Consortium for Hereditary Breast and Ovarian Cancer.
Rolfes, M., Borde, J., Möllenhoff, K., Kayali, M., Ernst, C., Gehrig, A., Sutter, C., Ramser, J., Niederacher, D., Horváth, J., Arnold, N., Meindl, A., Auber, B., Rump, A., Wang-Gohrke, S., Ritter, J., Hentschel, J., Thiele, H., Altmüller, J., Nürnberg, P., Rhiem, K., Engel, C., Wappenschmidt, B., Schmutzler, R.K., Hahnen, E. and Hauke, J.
Cancers 14 (13): 3292. 5 July 2022

A RAS-independent biomarker panel to reliably predict response to MEK inhibition in colorectal cancer.
Pfohl, U., Loskutov, J., Bashir, S., Kühn, R., Herter, P., Templin, M., Mamlouk, S., Belanov, S., Linnebacher, M., Bürtin, F., Vetter, M., Reinhard, C., Wedeken, L. and Regenbrecht, C.R.A.
Cancers 14 (13): 3252. 1 July 2022

Targeting Wnt/β-catenin signaling by TET1/FOXO4 inhibits metastatic spreading and self-renewal of cancer stem cells in gastric cancer.
Qi, J., Cui, D., Wu, Q.N., Zhao, Q., Chen, Z.H., Li, L., Birchmeier, W., Yu, Y. and Tao, R.
Cancers 14 (13): 3232. 30 June 2022

Evidence for recombinant GRP78, CALR, PDIA3 and GPI as mediators of genetic instability in human CD34+ cells.
Fabarius, A., Samra, V., Drews, O., Mörz, H., Bierbaum, M., Darwich, A., Weiss, C., Brendel, S., Kleiner, H., Seifarth, W., Greffrath, W., Hofmann, W.K., Schmitt, C.A. and Popp, H.D.
Cancers 14 (12): 2883. 11 June 2022

MACC1-induced collective migration is promoted by proliferation rather than single cell biomechanics.
Hohmann, T., Hohmann, U., Dahlmann, M., Kobelt, D., Stein, U. and Dehghani, F.
Cancers 14 (12): 2857. 9 June 2022

(RB1)-negative retinal organoids display proliferation of cone photoreceptors and loss of retinal differentiation.
Kanber, D., Woestefeld, J., Döpper, H., Bozet, M., Brenzel, A., Altmüller, J., Kilpert, F., Lohmann, D., Pommerenke, C. and Steenpass, L.
Cancers 14 (9): 2166. 26 April 2022

Circulating cell-free DNA assessment in biofluids from children with neuroblastoma demonstrates feasibility and potential for minimally invasive molecular diagnostics.
Lodrini, M., Wünschel, J., Thole-Kliesch, T.M., Grimaldi, M., Sprüssel, A., Linke, R.B., Hollander, J.F., Tiburtius, D., Künkele, A., Schulte, J.H., Lankes, E., Elgeti, T., Hundsdörfer, P., Astrahantseff, K., Simon, T., Eggert, A. and Deubzer, H.E.
Cancers 14 (9): 2080. 21 April 2022

Isolation of neoantigen-specific human T cell receptors from different human and murine repertoires.
Grunert, C., Willimsky, G., Peuker, C.A., Rhein, S., Hansmann, L., Blankenstein, T., Blanc, E., Beule, D., Keller, U., Pezzutto, A. and Busse, A.
Cancers 14 (7): 1842. 6 April 2022

Elevated MACC1 expression in colorectal cancer is driven by chromosomal instability and is associated with molecular subtype and worse patient survival.
Vuaroqueaux, V., Musch, A., Kobelt, D., Risch, T:, Herrmann, P., Burock, S., Peille, A.L., Yaspo, M.L., Fiebig, H.H. and Stein, U.
Cancers 14 (7): 1749. 1 April 2022

Inhibition of MACC1-induced metastasis in esophageal and gastric adenocarcinomas.
Treese, C., Werchan, J., von Winterfeld, M., Berg, E., Hummel, M., Timm, L., Rau, B., Daberkow, O., Walther, W., Daum, S., Kobelt, D. and Stein, U.
Cancers 14 (7): 1773. 31 March 2022

Refining AML treatment: the role of genetics in response and resistance evaluation to new agents.
Halik, A., Arends, C.M., Bullinger, L., Damm, F. and Frick, M.
Cancers 14 (7): 1689. 26 March 2022

DLBCL 1L-what to expect beyond R-CHOP?
Stegemann, M., Denker, S. and Schmitt, C.A.
Cancers 14 (6): 1453. 11 March 2022

Combination of Wnt/β-catenin targets S100A4 and DKK1 improves prognosis of human colorectal cancer.
Dahlmann, M., Monks, A., Harris, E.D., Kobelt, D., Osterland, M., Khaireddine, F., Herrmann, P., Kemmner, W., Burock, S., Walther, W., Shoemaker, R.H. and Stein, U.
Cancers 14 (1): 37. 2022

2021

Inhibiting lysine demethylase 1A improves L1CAM-specific CAR T cell therapy by unleashing antigen-independent killing via the FAS-FASL axis.
Sulejmani, O., Grunewald, L., Andersch, L., Schwiebert, S., Klaus, A., Winkler, A., Astrahantseff, K., Eggert, A., Henssen, A.G., Schulte, J.H., Anders, K. and Künkele, A.
Cancers 13 (21): 5489. 31 October 2021

Current applications and future development of magnetic resonance fingerprinting in diagnosis, characterization, and response monitoring in cancer.
Ding, H., Velasco, C., Ye, H., Lindner, T., Grech-Sollars, M., O’Callaghan, J., Hiley, C., Chouhan, M.D., Niendorf, T., Koh, D.M., Prieto, C. and Adeleke, S.
Cancers 13 (19): 4742. 1 October 2021

Aberrant expression of and cell death induction by engagement of the MHC-II chaperone CD74 in anaplastic large cell lymphoma (ALCL).
Wurster, K.D., Costanza, M., Kreher, S., Glaser, S., Lamprecht, B., Schleussner, N., Anagnostopoulos, I., Hummel, M., Jöhrens, K., Stein, H., Molina, A., Diepstra, A., Gillissen, B., Köchert, K., Siebert, R., Merkel, O., Kenner, L., Janz, M. and Mathas, S.
Cancers 13 (19): 5012. 1 October 2021

Elevated Flt3L predicts long-term survival in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms.
Detjen, K.M., Otto, R., Giesecke, Y., Geisler, L., Riemer, P., Jann, H., Grötzinger, C., Sers, C., Pascher, A., Lüdde, T., Leser, U., Wiedenmann, B., Sigal, M., Tacke, F., Roderburg, C. and Hammerich, L.
Cancers 13 (17): 4463. 1 September 2021

Effective oncoleaking treatment of pancreatic cancer by claudin-targeted suicide gene therapy with Clostridium perfringens enterotoxin (CPE).
Pahle, J., Kobelt, D., Aumann, J., Behrens, D., Daberkow, O., Mokritzkij, M., Piontek, J., Stein, U. and Walther, W.
Cancers 13 (17): 4393. 1 September 2021

Spontaneous non-sustained ventricular tachycardia and premature ventricular contractions and their prognostic relevance in patients with cancer in routine care.
Albrecht, A., Porthun, J., Eucker, J., Coats, A.J.S., von Haehling, S., Pezzutto, A., Karakas, M., Riess, H., Keller, U., Landmesser, U., Haverkamp, W., Anker, S.D. and Anker, M.S.
Cancers 13 (10): 2303. 12 May 2021

Patient-specific planning for thermal magnetic resonance of glioblastoma multiforme.
Oberacker, E., Diesch, C., Nadobny, J., Kuehne, A., Wust, P., Ghadjar, P. and Niendorf, T.
Cancers 13 (8): 1867. 2 April 2021

ECG scoring for the evaluation of therapy-naïve cancer patients to predict cardiotoxicity.
Pohl, J., Mincu, R.I., Mrotzek, S.M., Wakili, R., Mahabadi, A.A., Potthoff, S.K., Siveke, J.T., Keller, U., Landmesser, U., Rassaf, T., Anker, M.S. and Totzeck, M.
Cancers 13 (6): 1197. 10 March 2021

CD28 co-stimulus achieves superior CAR T cell effector function against solid tumors than 4-1BB co-stimulus.
Textor, A., Grunewald, L., Anders, K., Klaus, A., Schwiebert, S., Winkler, A., Stecklum, M., Rolff, J., Henssen, A.G., Höpken, U.E., Eggert, A., Schulte, J.H., Jensen, M.C., Blankenstein, T. and Künkele, A.
Cancers 13 (5): 1050. 2 March 2021

Multi-channel RF supervision module for thermal magnetic resonance based cancer therapy.
Han, H., Oberacker, E., Kuehne, A., Wang, S., Eigentler, T.W., Grass, E. and Niendorf, T.
Cancers 13 (5): 1001. 28 February 2021

Systematic identification of MACC1-driven metabolic networks in colorectal cancer.
Lisec, J., Kobelt, D., Walther, W., Mokrizkij, M., Grötzinger, C., Jaeger, C., Baum, K., Simon, M., Wolf, J., Beindorff, N., Brenner, W. and Stein, U.
Cancers 13 (5): 978. 26 February 2021

The relevance of the SH2 domain for c-Src functionality in triple-negative breast cancer cells.
Mayoral-Varo, V., Sánchez-Bailón, M.P., Calcabrini, A., García-Hernández, M., Frezza, V., Martín, M.E., González, V.M. and Martín-Pérez, J.
Cancers 13 (3): 462. 26 January 2021

Cold-shock domains - abundance, structure, properties, and nucleic-acid binding.
Heinemann, U. and Roske, Y.
Cancers 13 (2): 190. 7 January 2021

Gene expression signatures of a preclinical mouse model during colorectal cancer progression under low-dose metronomic chemotherapy.
Ho-Xuan, H., Lehmann, G., Glazar, P., Gypas, F., Eichner, N., Heizler, K., Schlitt, H.J., Zavolan, M., Rajewsky, N., Meister, G. and Hackl, C.
Cancers 13 (1): 49. 2021

2020

Ubiquitination and ubiquitin-like modifications in multiple myeloma: biology and therapy.
Wirth, M., Schick, M., Keller, U. and Krönke, J.
Cancers 12 (12): 3764. 14 December 2020

Design, implementation, evaluation and application of a 32-channel radio frequency signal generator for thermal magnetic resonance based anti-cancer treatment.
Han, H., Eigentler, T.W., Wang, S., Kretov, E., Winter, L., Hoffmann, W., Grass, E. and Niendorf, T.
Cancers 12 (7): 1720. 28 June 2020

Small ones to fight a big problem-intervention of cancer metastasis by small molecules.
Kobelt, D., Dahlmann, M., Dumbani, M., Güllü, N., Kortüm, B., Vílchez, M.E.A., Stein, U. and Walther, W.
Cancers 12 (6): 1454. 3 June 2020

Progression-dependent altered metabolism in osteosarcoma resulting in different nutrient source dependencies.
Fritsche-Guenther, R., Gloaguen, Y., Kirchner, M., Mertins, P., Tunn, P.U. and Kirwan, J.A.
Cancers 12 (6): 1371. 27 May 2020

Controlled release of therapeutics from thermoresponsive nanogels: a thermal magnetic resonance feasibility study.
Ji, Y., Winter, L., Navarro, L., Ku, M.C., Periquito, J.S., Pham, M., Hoffmann, W., Theune, L.E., Calderón, M. and Niendorf, T.
Cancers 12 (6): 1380. 27 May 2020

Solving the time- and frequency-multiplexed problem of constrained radiofrequency induced hyperthermia.
Kuehne, A., Oberacker, E., Waiczies, H. and Niendorf, T.
Cancers 12 (5): 1072. May 2020

Functional classification of TP53 mutations in acute myeloid leukemia.
Dutta, S., Pregartner, G., Rücker, F.G., Heitzer, E., Zebisch, A., Bullinger, L., Berghold, A., Döhner, K. and Sill, H.
Cancers 12 (3): 637. 10 March 2020

High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive Ewing sarcoma.
Orth, M.F., Hölting, T.L.B., Dallmayer, M., Wehweck, F.S., Paul, T., Musa, J., Baldauf, M.C., Surdez, D., Delattre, O., Knott, M.M.L., Romero-Pérez, L., Kasan, M., Cidre-Aranaz, F., Gerke, J.S., Ohmura, S., Li, J., Marchetto, A., Henssen, A.G., Özen, Ö., Sugita, S., Hasegawa, T., Kanaseki, T., Bertram, S., Dirksen, U., Hartmann, W., Kirchner, T. and Grünewald, T.G.P.
Cancers 12 (3): 644. 10 March 2020

Efficacy of crizotinib, ceritinib, and alectinib in ALK-positive non-small cell lung cancer treatment: a meta-analysis of clinical trials.
Hoang, T., Myung, S.K., Pham, T.T. and Park, B.
Cancers 12 (3): 526. 25 February 2020

2019

Hypertonicity-affected genes are differentially expressed in clear cell renal cell carcinoma and correlate with cancer-specific survival.
Kandabarau, S., Leiz, J., Krohn, K., Winter, S., Bedke, J., Schwab, M., Schaeffeler, E. and Edemir, B.
Cancers 12 (1): 6. 18 December 2019

A novel predictor tool of biochemical recurrence after radical prostatectomy based on a five-microRNA tissue signature.
Zhao, Z., Weickmann, S., Jung, M., Lein, M., Kilic, E., Stephan, C., Erbersdobler, A., Fendler, A. and Jung, K.
Cancers 11 (10): 1603. 21 October 2019

Circular RNAs in clear cell renal cell carcinoma: their microarray-based identification, analytical validation, and potential use in a clinico-genomic model to improve prognostic accuracy.
Franz, A., Ralla, B., Weickmann, S., Jung, M., Rochow, H., Stephan, C., Erbersdobler, A., Kilic, E., Fendler, A. and Jung, K.
Cancers 11 (10): 1473. 30 September 2019

Circulating MACC1 transcripts in glioblastoma patients predict prognosis and treatment response.
Hagemann, C., Neuhaus, N., Dahlmann, M., Kessler, A.F., Kobelt, D., Herrmann, P., Eyrich, M., Freitag, B., Linsenmann, T., Monoranu, C.M., Ernestus, R.I., Löhr, M. and Stein, U.
Cancers 11 (6): 825. 13 June 2019

2018

miR-9-5p in nephrectomy specimens is a potential predictor of primary resistance to first-line treatment with tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma.
Ralla, B., Busch, J., Flörcken, A., Westermann, J., Zhao, Z., Kilic, E., Weickmann, S., Jung, M., Fendler, A. and Jung, K.
Cancers 10 (9): 321. 10 September 2018

2016

S100A4 in cancer metastasis: Wnt signaling-driven interventions for metastasis restriction.
Dahlmann, M., Kobelt, D., Walther, W., Mudduluru, G. and Stein, U.
Cancers 8 (6): 59. 20 June 2016