Browse by Journal Title

2024

Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies.
Torke, S. and Walther, W. and Stein, U.
Cancers 16 (7): 1330. 28 March 2024

MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer.
Erdem, M. and Lee, K.H. and Hardt, M. and Regan, J.L. and Kobelt, D. and Walther, W. and Mokrizkij, M. and Regenbrecht, C. and Stein, U.
Cancers 16 (3): 604. 31 January 2024

2023

Establishment and thorough characterization of xenograft (PDX) models derived from patients with pancreatic cancer for molecular analyses and chemosensitivity testing.
Behrens, D. and Pfohl, U. and Conrad, T. and Becker, M. and Brzezicha, B. and Büttner, B. and Wagner, S. and Hallas, C. and Lawlor, R. and Khazak, V. and Linnebacher, M. and Wartmann, T. and Fichtner, I. and Hoffmann, J. and Dahlmann, M. and Walther, W.
Cancers 15 (24): 5753. 8 December 2023

Mechanisms of resistance to small molecules in acute myeloid leukemia.
Lang, T.J.L. and Damm, F. and Bullinger, L. and Frick, M.
Cancers 15 (18): 4573. 15 September 2023

Metastasis associated in colorectal cancer 1 (MACC1) mRNA expression is enhanced in sporadic vestibular schwannoma and correlates to deafness.
Breun, M. and Flock, K. and Feldheim, J. and Nattmann, A. and Monoranu, C.M. and Herrmann, P. and Ernestus, R.I. and Löhr, M. and Hagemann, C. and Stein, U.
Cancers 15 (16): 4089. 14 August 2023

Advanced radio frequency applicators for thermal magnetic resonance theranostics of brain tumors.
Saha, N. and Kuehne, A. and Millward, J.M. and Eigentler, T.W. and Starke, L. and Waiczies, S. and Niendorf, T.
Cancers 15 (8): 2303. 14 April 2023

2022

Multi-omics alleviates the limitations of panel sequencing for cancer drug response prediction.
Baranovskii, A. and Gündüz, I.B. and Franke, V. and Uyar, B. and Akalin, A.
Cancers 14 (22): 5604. 15 November 2022

Pre-diagnostic circulating resistin concentrations are not associated with colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study.
Pham, T.T. and Nimptsch, K. and Aleksandrova, K. and Jenab, M. and Reichmann, R. and Wu, K. and Tjønneland, A. and Kyrø, C. and Schulze, M.B. and Kaaks, R. and Katzke, V. and Palli, D. and Pasanisi, F. and Ricceri, F. and Tumino, R. and Krogh, V. and Roodhart, J. and Castilla, J. and Sánchez, M.J. and Colorado-Yohar, S.M. and Harbs, J. and Rutegård, M. and Papier, K. and Aglago, E.K. and Dimou, N. and Mayen-Chacon, A.L. and Weiderpass, E. and Pischon, T.
Cancers 14 (22): 5499. 9 November 2022

The monocyte, a maestro in the tumor microenvironment (TME) of breast cancer.
Amer, H.T. and Stein, U. and El Tayebi, H.M.
Cancers 14 (21): 5460. 7 November 2022

Radiofrequency electromagnetic fields cause non-temperature-induced physical and biological effects in cancer cells.
Wust, P. and Veltsista, P.D. and Oberacker, E. and Yavvari, P. and Walther, W. and Bengtsson, O. and Sterner-Kock, A. and Weinhart, M. and Heyd, F. and Grabowski, P. and Stintzing, S. and Heinrich, W. and Stein, U. and Ghadjar, P.
Cancers 14 (21): 5349. 30 October 2022

Concomitant cytotoxic effector differentiation of CD4(+) and CD8(+) T cells in response to EBV-Infected B cells.
Tamura, Y. and Yamane, K. and Kawano, Y. and Bullinger, L. and Wirtz, T. and Weber, T. and Sander, S. and Ohki, S. and Kitajima, Y. and Okada, S. and Rajewsky, K. and Yasuda, T.
Cancers 14 (17): 4118. 25 August 2022

Core-clock genes regulate proliferation and invasion via a reciprocal interplay with MACC1 in colorectal cancer cells.
Basti, A. and Malhan, D. and Dumbani, M. and Dahlmann, M. and Stein, U. and Relógio, A.
Cancers 14 (14): 3458. 16 July 2022

Uncovering the contribution of moderate-penetrance susceptibility genes to breast cancer by whole-exome sequencing and targeted enrichment sequencing of candidate genes in women of European ancestry.
Dumont, M. and Weber-Lassalle, N. and Joly-Beauparlant, C. and Ernst, C. and Droit, A. and Feng, B.J. and Dubois, S. and Collin-Deschesnes, A.C. and Soucy, P. and Vallée, M. and Fournier, F. and Lemaçon, A. and Adank, M.A. and Allen, J. and Altmüller, J. and Arnold, N. and Ausems, M.G.E.M. and Berutti, R. and Bolla, M.K. and Bull, S. and Carvalho, S. and Cornelissen, S. and Dufault, M.R. and Dunning, A.M. and Engel, C. and Gehrig, A. and Geurts-Giele, W.R.R. and Gieger, C. and Green, J. and Hackmann, K. and Helmy, M. and Hentschel, J. and Hogervorst, F.B.L. and Hollestelle, A. and Hooning, M.J. and Horváth, J. and Ikram, M.A. and Kaulfuß, S. and Keeman, R. and Kuang, D. and Luccarini, C. and Maier, W. and Martens, J.W.M. and Niederacher, D. and Nürnberg, P. and Ott, C.E. and Peters, A. and Pharoah, P.D.P. and Ramirez, A. and Ramser, J. and Riedel-Heller, S. and Schmidt, G. and Shah, M. and Scherer, M. and Stäbler, A. and Strom, T.M. and Sutter, C. and Thiele, H. and van Asperen, C.J. and van der Kolk, L. and van der Luijt, R.B. and Volk, A.E. and Wagner, M. and Waisfisz, Q. and Wang, Q. and Wang-Gohrke, S. and Weber, B.H.F. and Devilee, P. and Tavtigian, S. and Bader, G.D. and Meindl, A. and Goldgar, D.E. and Andrulis, I.L. and Schmutzler, R.K. and Easton, D.F. and Schmidt, M.K. and Hahnen, E. and Simard, J.
Cancers 14 (14): 3363. 11 July 2022

Prevalence of cancer predisposition germline variants in male breast cancer patients: results of the German Consortium for Hereditary Breast and Ovarian Cancer.
Rolfes, M. and Borde, J. and Möllenhoff, K. and Kayali, M. and Ernst, C. and Gehrig, A. and Sutter, C. and Ramser, J. and Niederacher, D. and Horváth, J. and Arnold, N. and Meindl, A. and Auber, B. and Rump, A. and Wang-Gohrke, S. and Ritter, J. and Hentschel, J. and Thiele, H. and Altmüller, J. and Nürnberg, P. and Rhiem, K. and Engel, C. and Wappenschmidt, B. and Schmutzler, R.K. and Hahnen, E. and Hauke, J.
Cancers 14 (13): 3292. 5 July 2022

A RAS-independent biomarker panel to reliably predict response to MEK inhibition in colorectal cancer.
Pfohl, U. and Loskutov, J. and Bashir, S. and Kühn, R. and Herter, P. and Templin, M. and Mamlouk, S. and Belanov, S. and Linnebacher, M. and Bürtin, F. and Vetter, M. and Reinhard, C. and Wedeken, L. and Regenbrecht, C.R.A.
Cancers 14 (13): 3252. 1 July 2022

Targeting Wnt/β-catenin signaling by TET1/FOXO4 inhibits metastatic spreading and self-renewal of cancer stem cells in gastric cancer.
Qi, J. and Cui, D. and Wu, Q.N. and Zhao, Q. and Chen, Z.H. and Li, L. and Birchmeier, W. and Yu, Y. and Tao, R.
Cancers 14 (13): 3232. 30 June 2022

Evidence for recombinant GRP78, CALR, PDIA3 and GPI as mediators of genetic instability in human CD34+ cells.
Fabarius, A. and Samra, V. and Drews, O. and Mörz, H. and Bierbaum, M. and Darwich, A. and Weiss, C. and Brendel, S. and Kleiner, H. and Seifarth, W. and Greffrath, W. and Hofmann, W.K. and Schmitt, C.A. and Popp, H.D.
Cancers 14 (12): 2883. 11 June 2022

MACC1-induced collective migration is promoted by proliferation rather than single cell biomechanics.
Hohmann, T. and Hohmann, U. and Dahlmann, M. and Kobelt, D. and Stein, U. and Dehghani, F.
Cancers 14 (12): 2857. 9 June 2022

(RB1)-negative retinal organoids display proliferation of cone photoreceptors and loss of retinal differentiation.
Kanber, D. and Woestefeld, J. and Döpper, H. and Bozet, M. and Brenzel, A. and Altmüller, J. and Kilpert, F. and Lohmann, D. and Pommerenke, C. and Steenpass, L.
Cancers 14 (9): 2166. 26 April 2022

Circulating cell-free DNA assessment in biofluids from children with neuroblastoma demonstrates feasibility and potential for minimally invasive molecular diagnostics.
Lodrini, M. and Wünschel, J. and Thole-Kliesch, T.M. and Grimaldi, M. and Sprüssel, A. and Linke, R.B. and Hollander, J.F. and Tiburtius, D. and Künkele, A. and Schulte, J.H. and Lankes, E. and Elgeti, T. and Hundsdörfer, P. and Astrahantseff, K. and Simon, T. and Eggert, A. and Deubzer, H.E.
Cancers 14 (9): 2080. 21 April 2022

Isolation of neoantigen-specific human T cell receptors from different human and murine repertoires.
Grunert, C. and Willimsky, G. and Peuker, C.A. and Rhein, S. and Hansmann, L. and Blankenstein, T. and Blanc, E. and Beule, D. and Keller, U. and Pezzutto, A. and Busse, A.
Cancers 14 (7): 1842. 6 April 2022

Elevated MACC1 expression in colorectal cancer is driven by chromosomal instability and is associated with molecular subtype and worse patient survival.
Vuaroqueaux, V. and Musch, A. and Kobelt, D. and Risch, T: and Herrmann, P. and Burock, S. and Peille, A.L. and Yaspo, M.L. and Fiebig, H.H. and Stein, U.
Cancers 14 (7): 1749. 1 April 2022

Inhibition of MACC1-induced metastasis in esophageal and gastric adenocarcinomas.
Treese, C. and Werchan, J. and von Winterfeld, M. and Berg, E. and Hummel, M. and Timm, L. and Rau, B. and Daberkow, O. and Walther, W. and Daum, S. and Kobelt, D. and Stein, U.
Cancers 14 (7): 1773. 31 March 2022

Refining AML treatment: the role of genetics in response and resistance evaluation to new agents.
Halik, A. and Arends, C.M. and Bullinger, L. and Damm, F. and Frick, M.
Cancers 14 (7): 1689. 26 March 2022

DLBCL 1L-what to expect beyond R-CHOP?
Stegemann, M. and Denker, S. and Schmitt, C.A.
Cancers 14 (6): 1453. 11 March 2022

2021

Combination of Wnt/β-catenin targets S100A4 and DKK1 improves prognosis of human colorectal cancer.
Dahlmann, M. and Monks, A. and Harris, E.D. and Kobelt, D. and Osterland, M. and Khaireddine, F. and Herrmann, P. and Kemmner, W. and Burock, S. and Walther, W. and Shoemaker, R.H. and Stein, U.
Cancers 14 (1): 37. 22 December 2021

Inhibiting lysine demethylase 1A improves L1CAM-specific CAR T cell therapy by unleashing antigen-independent killing via the FAS-FASL axis.
Sulejmani, O. and Grunewald, L. and Andersch, L. and Schwiebert, S. and Klaus, A. and Winkler, A. and Astrahantseff, K. and Eggert, A. and Henssen, A.G. and Schulte, J.H. and Anders, K. and Künkele, A.
Cancers 13 (21): 5489. 31 October 2021

Current applications and future development of magnetic resonance fingerprinting in diagnosis, characterization, and response monitoring in cancer.
Ding, H. and Velasco, C. and Ye, H. and Lindner, T. and Grech-Sollars, M. and O’Callaghan, J. and Hiley, C. and Chouhan, M.D. and Niendorf, T. and Koh, D.M. and Prieto, C. and Adeleke, S.
Cancers 13 (19): 4742. 1 October 2021

Aberrant expression of and cell death induction by engagement of the MHC-II chaperone CD74 in anaplastic large cell lymphoma (ALCL).
Wurster, K.D. and Costanza, M. and Kreher, S. and Glaser, S. and Lamprecht, B. and Schleussner, N. and Anagnostopoulos, I. and Hummel, M. and Jöhrens, K. and Stein, H. and Molina, A. and Diepstra, A. and Gillissen, B. and Köchert, K. and Siebert, R. and Merkel, O. and Kenner, L. and Janz, M. and Mathas, S.
Cancers 13 (19): 5012. 1 October 2021

Elevated Flt3L predicts long-term survival in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms.
Detjen, K.M. and Otto, R. and Giesecke, Y. and Geisler, L. and Riemer, P. and Jann, H. and Grötzinger, C. and Sers, C. and Pascher, A. and Lüdde, T. and Leser, U. and Wiedenmann, B. and Sigal, M. and Tacke, F. and Roderburg, C. and Hammerich, L.
Cancers 13 (17): 4463. 1 September 2021

Effective oncoleaking treatment of pancreatic cancer by claudin-targeted suicide gene therapy with Clostridium perfringens enterotoxin (CPE).
Pahle, J. and Kobelt, D. and Aumann, J. and Behrens, D. and Daberkow, O. and Mokritzkij, M. and Piontek, J. and Stein, U. and Walther, W.
Cancers 13 (17): 4393. 1 September 2021

Spontaneous non-sustained ventricular tachycardia and premature ventricular contractions and their prognostic relevance in patients with cancer in routine care.
Albrecht, A. and Porthun, J. and Eucker, J. and Coats, A.J.S. and von Haehling, S. and Pezzutto, A. and Karakas, M. and Riess, H. and Keller, U. and Landmesser, U. and Haverkamp, W. and Anker, S.D. and Anker, M.S.
Cancers 13 (10): 2303. 12 May 2021

Patient-specific planning for thermal magnetic resonance of glioblastoma multiforme.
Oberacker, E. and Diesch, C. and Nadobny, J. and Kuehne, A. and Wust, P. and Ghadjar, P. and Niendorf, T.
Cancers 13 (8): 1867. 2 April 2021

ECG scoring for the evaluation of therapy-naïve cancer patients to predict cardiotoxicity.
Pohl, J. and Mincu, R.I. and Mrotzek, S.M. and Wakili, R. and Mahabadi, A.A. and Potthoff, S.K. and Siveke, J.T. and Keller, U. and Landmesser, U. and Rassaf, T. and Anker, M.S. and Totzeck, M.
Cancers 13 (6): 1197. 10 March 2021

CD28 co-stimulus achieves superior CAR T cell effector function against solid tumors than 4-1BB co-stimulus.
Textor, A. and Grunewald, L. and Anders, K. and Klaus, A. and Schwiebert, S. and Winkler, A. and Stecklum, M. and Rolff, J. and Henssen, A.G. and Höpken, U.E. and Eggert, A. and Schulte, J.H. and Jensen, M.C. and Blankenstein, T. and Künkele, A.
Cancers 13 (5): 1050. 2 March 2021

Multi-channel RF supervision module for thermal magnetic resonance based cancer therapy.
Han, H. and Oberacker, E. and Kuehne, A. and Wang, S. and Eigentler, T.W. and Grass, E. and Niendorf, T.
Cancers 13 (5): 1001. 28 February 2021

Systematic identification of MACC1-driven metabolic networks in colorectal cancer.
Lisec, J. and Kobelt, D. and Walther, W. and Mokrizkij, M. and Grötzinger, C. and Jaeger, C. and Baum, K. and Simon, M. and Wolf, J. and Beindorff, N. and Brenner, W. and Stein, U.
Cancers 13 (5): 978. 26 February 2021

The relevance of the SH2 domain for c-Src functionality in triple-negative breast cancer cells.
Mayoral-Varo, V. and Sánchez-Bailón, M.P. and Calcabrini, A. and García-Hernández, M. and Frezza, V. and Martín, M.E. and González, V.M. and Martín-Pérez, J.
Cancers 13 (3): 462. 26 January 2021

Cold-shock domains - abundance, structure, properties, and nucleic-acid binding.
Heinemann, U. and Roske, Y.
Cancers 13 (2): 190. 7 January 2021

Gene expression signatures of a preclinical mouse model during colorectal cancer progression under low-dose metronomic chemotherapy.
Ho-Xuan, H. and Lehmann, G. and Glazar, P. and Gypas, F. and Eichner, N. and Heizler, K. and Schlitt, H.J. and Zavolan, M. and Rajewsky, N. and Meister, G. and Hackl, C.
Cancers 13 (1): 49. 2021

2020

Ubiquitination and ubiquitin-like modifications in multiple myeloma: biology and therapy.
Wirth, M. and Schick, M. and Keller, U. and Krönke, J.
Cancers 12 (12): 3764. 14 December 2020

Design, implementation, evaluation and application of a 32-channel radio frequency signal generator for thermal magnetic resonance based anti-cancer treatment.
Han, H. and Eigentler, T.W. and Wang, S. and Kretov, E. and Winter, L. and Hoffmann, W. and Grass, E. and Niendorf, T.
Cancers 12 (7): 1720. 28 June 2020

Small ones to fight a big problem-intervention of cancer metastasis by small molecules.
Kobelt, D. and Dahlmann, M. and Dumbani, M. and Güllü, N. and Kortüm, B. and Vílchez, M.E.A. and Stein, U. and Walther, W.
Cancers 12 (6): 1454. 3 June 2020

Progression-dependent altered metabolism in osteosarcoma resulting in different nutrient source dependencies.
Fritsche-Guenther, R. and Gloaguen, Y. and Kirchner, M. and Mertins, P. and Tunn, P.U. and Kirwan, J.A.
Cancers 12 (6): 1371. 27 May 2020

Controlled release of therapeutics from thermoresponsive nanogels: a thermal magnetic resonance feasibility study.
Ji, Y. and Winter, L. and Navarro, L. and Ku, M.C. and Periquito, J.S. and Pham, M. and Hoffmann, W. and Theune, L.E. and Calderón, M. and Niendorf, T.
Cancers 12 (6): 1380. 27 May 2020

Solving the time- and frequency-multiplexed problem of constrained radiofrequency induced hyperthermia.
Kuehne, A. and Oberacker, E. and Waiczies, H. and Niendorf, T.
Cancers 12 (5): 1072. May 2020

Functional classification of TP53 mutations in acute myeloid leukemia.
Dutta, S. and Pregartner, G. and Rücker, F.G. and Heitzer, E. and Zebisch, A. and Bullinger, L. and Berghold, A. and Döhner, K. and Sill, H.
Cancers 12 (3): 637. 10 March 2020

High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive Ewing sarcoma.
Orth, M.F. and Hölting, T.L.B. and Dallmayer, M. and Wehweck, F.S. and Paul, T. and Musa, J. and Baldauf, M.C. and Surdez, D. and Delattre, O. and Knott, M.M.L. and Romero-Pérez, L. and Kasan, M. and Cidre-Aranaz, F. and Gerke, J.S. and Ohmura, S. and Li, J. and Marchetto, A. and Henssen, A.G. and Özen, Ö. and Sugita, S. and Hasegawa, T. and Kanaseki, T. and Bertram, S. and Dirksen, U. and Hartmann, W. and Kirchner, T. and Grünewald, T.G.P.
Cancers 12 (3): 644. 10 March 2020

Efficacy of crizotinib, ceritinib, and alectinib in ALK-positive non-small cell lung cancer treatment: a meta-analysis of clinical trials.
Hoang, T. and Myung, S.K. and Pham, T.T. and Park, B.
Cancers 12 (3): 526. 25 February 2020

2019

Hypertonicity-affected genes are differentially expressed in clear cell renal cell carcinoma and correlate with cancer-specific survival.
Kandabarau, S. and Leiz, J. and Krohn, K. and Winter, S. and Bedke, J. and Schwab, M. and Schaeffeler, E. and Edemir, B.
Cancers 12 (1): 6. 18 December 2019

A novel predictor tool of biochemical recurrence after radical prostatectomy based on a five-microRNA tissue signature.
Zhao, Z. and Weickmann, S. and Jung, M. and Lein, M. and Kilic, E. and Stephan, C. and Erbersdobler, A. and Fendler, A. and Jung, K.
Cancers 11 (10): 1603. 21 October 2019

Circular RNAs in clear cell renal cell carcinoma: their microarray-based identification, analytical validation, and potential use in a clinico-genomic model to improve prognostic accuracy.
Franz, A. and Ralla, B. and Weickmann, S. and Jung, M. and Rochow, H. and Stephan, C. and Erbersdobler, A. and Kilic, E. and Fendler, A. and Jung, K.
Cancers 11 (10): 1473. 30 September 2019

Circulating MACC1 transcripts in glioblastoma patients predict prognosis and treatment response.
Hagemann, C. and Neuhaus, N. and Dahlmann, M. and Kessler, A.F. and Kobelt, D. and Herrmann, P. and Eyrich, M. and Freitag, B. and Linsenmann, T. and Monoranu, C.M. and Ernestus, R.I. and Löhr, M. and Stein, U.
Cancers 11 (6): 825. 13 June 2019

2018

miR-9-5p in nephrectomy specimens is a potential predictor of primary resistance to first-line treatment with tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma.
Ralla, B. and Busch, J. and Flörcken, A. and Westermann, J. and Zhao, Z. and Kilic, E. and Weickmann, S. and Jung, M. and Fendler, A. and Jung, K.
Cancers 10 (9): 321. 10 September 2018

2016

S100A4 in cancer metastasis: Wnt signaling-driven interventions for metastasis restriction.
Dahlmann, M. and Kobelt, D. and Walther, W. and Mudduluru, G. and Stein, U.
Cancers 8 (6): 59. 20 June 2016